116 results about "Patchouli" patented technology

The invention discloses a substance-based quality detection method for Xiaohuang powder, and belongs to the technical field of quality detection of traditional Chinese medicines. According to the method, standard control of a classic famous prescription is realized by constructing a multi-dimensional quality control system. The method comprises the following steps: firstly, carrying out specific identification on gardenia, divaricate saposhnikovia root, liquorice and pogostemon cablin in the prescription by adopting a thin-layer chromatography; meanwhile, a multi-index component content determination method is established, and the contents of five components including geniposide, cimicifugin, 5-O-methylvisammioside, liquiritin and glycyrrhizic acid are synchronously determined by applying a high performance liquid chromatography (HPLC). Through a system quality control strategy combining qualitative identification and quantitative analysis, not only is a quality standard system of the substance reference of the Xiaohuang powder perfected, but also reliable technical guarantee is provided for ensuring the stability and consistency of product quality. The establishment of the method establishes a standardized method system for the substance-based quality control of the classical famous prescription Xiaohuang powder.

The invention discloses a saccharomyces cerevisiae recombinant strain based on a uracil metabolism gene URA3 as well as a construction method and application of the saccharomyces cerevisiae recombinant strain. The construction method comprises the following steps: taking saccharomyces cerevisiae rich in farnesyl pyrophosphate as an original strain, introducing a uracil metabolism gene URA3, synchronously overexpressing a ribosome biosynthetic gene UTP10 and an iron metabolism gene FIT3, and utilizing the uracil metabolism gene URA3 to express up-regulation correlation with the ribosome biosynthetic gene UTP10 and the iron metabolism gene FIT3, so as to obtain the farnesyl pyrophosphate-rich saccharomyces cerevisiae. The metabolic flux of the terpenoids is enhanced, and the saccharomyces cerevisiae recombinant strain for efficiently producing the terpenoids is constructed. According to the method, a metabolic network of yeast is systematically optimized, and combined regulation and control on precursor flux distribution, protein translation capability and metal ion steady state are realized, so that the microbial synthesis efficiency of sesquiterpenoids such as patchouli alcohol and beta-elemene is remarkably improved.

The invention provides a pogostemon cablin cold stress response transcription factor and application thereof in resisting cold and increasing pogostemon cablin alcohol content, and belongs to the technical field of gene engineering. The terpene metabolism cold response transcription factor PatbZIP6 and / or PatMYB5 is obtained through screening, the transcription factor obtained through screening can remarkably improve synthesis accumulation of patchouli alcohol through a genetic transformation method, the cold resistance of patchouli is improved, and the transcription factor can be used for breeding new varieties of patchouli.

The invention belongs to the technical field of ecological water, mainly relates to ecological water for removing fruit peculiar smell, and particularly relates to ecological water for removing fruit peculiar smell and a preparation method thereof. Neotame and glucose modified cortex phellodendri are matched with tupistra chinensis, pogostemon cablin, liquorice and clove to be decocted into a traditional Chinese medicine decoction. According to the invention, lactobacillus plantarum ATCC 8014 and bacillus subtilis ATCC 6633 are used for fermentation. The antibacterial activity of the ecological water is improved, and the bitter taste of the cortex phellodendri is effectively removed due to the synergism of the two sweetening agents, namely the neotame and the glucose. The bacillus subtilis HZ-72 antagonistic bacteria used in the invention can enhance the capability of inhibiting pathogenic bacteria. Syzygium aromaticum has antibacterial activity, pogostemon cablin has an antiviral effect, and the syzygium aromaticum and the pogostemon cablin cooperate to enhance the antibacterial The ecological water prepared by the invention can remove peculiar smell and preserve freshness, and has a great development prospect in the field of fruit preservation.

The invention discloses a pogostemon cablin essential oil clathrate compound preparation device, and relates to the technical field of medicine preparation, the pogostemon cablin essential oil clathrate compound preparation device comprises a kettle body, the bottom of the kettle body is an arc-shaped lower sealing head structure; the flow guide cone is arranged in the center of the bottom of the kettle body, and baffles are vertically arranged on the inner wall of the kettle body in a circumferential array mode; the stirring assembly is arranged in the kettle body, and the stirring assembly is used for being matched with the flow guide cone and the baffle and is used for guiding liquid in the kettle body to circularly flow up and down; the outer circulation high-shearing assembly comprises a high-speed shearing device, a suction inlet assembly is arranged at the side bottom of the kettle body and communicated with a feeding port of the high-speed shearing device, and a backflow port is formed in the side wall of the kettle body and communicated with a discharging port of the high-speed shearing device; an outer circulation passage is formed between the kettle body and the high-speed shearing device; the ultrasonic-assisted assembly is arranged near the suction inlet assembly; and the essential oil injection pipe is arranged in the flow guide cone.

This invention relates to the field of external moxibustion devices in traditional Chinese medicine, and in particular to a moxa stick for clearing dampness using the thunder-fire method, and its preparation method. The moxa stick comprises moxa wool, compound Chinese herbal powder, and moxa leaf paper; the compound Chinese herbal powder includes principal, assistant, adjuvant, and guiding herbs; the principal herbs include Evodia rutaecarpa, Cinnamomum cassia, and Ligusticum chuanxiong; the assistant herbs include stir-fried Atractylodes lancea, Poria cocos, Polyporus umbellatus, Alisma plantago-aquatica, stir-fried Atractylodes macrocephala, Astragalus membranaceus, and Amomum villosum; the adjuvant herbs include stir-fried Phellodendron chinense, Sophora flavescens, Artemisia capillaris, Gardenia jasminoides, Akebia quinata, Pinellia ternata, Centella asiatica, and Rosa laevigata root; the guiding herbs include Angelica dahurica, Pogostemon cablin, Angelica sinensis, Paeonia lactiflora, Glycyrrhiza uralensis, and Nelumbo nucifera leaf. This invention, guided by compound formulation theory, material innovation, process optimization, and packaging design, provides a thunder-fire moxa stick with strong targeted dampness-clearing properties, stable combustion performance, safety, portability, and controllable quality, showing promising application prospects.

The invention discloses a preparation method and application of a repairing and soothing composition. Aiming at the dissolvability difference of different components in the three extracts, a step-by-step combined extraction process is adopted for extraction, that is, stephania tetrandra is subjected to composite enzymolysis and then subjected to microwave-assisted extraction, citrus peel is subjected to low-temperature fermentation and then subjected to subcritical water extraction, and pogostemon cablin leaves are subjected to supercritical CO2 extraction and then subjected to ethanol gradient elution. After the three extracts extracted by the process are compounded, the composition has excellent skin barrier repairing, moisturizing and skin relieving effects, is safe and non-irritant, and can be used for uncomfortable skin after medical beauty and season change.

This invention provides a method for the separation, purification, and aroma quality control of biosynthesized patchouli essential oil, belonging to the field of daily chemical product purification technology. It solves the technical problems of low separation efficiency, insufficient purity, easy destruction of heat-sensitive components, and low aroma matching in existing essential oils. This method uses metabolically engineered brewer's yeast fermentation broth as raw material, sequentially undergoing pretreatment, multi-stage countercurrent extraction, three-stage high-vacuum distillation, column chromatography purification, activated carbon decolorization and deodorization, aroma component recombination, and product stabilization to obtain high-purity patchouli essential oil with high aroma matching. This invention is adapted to the three-stage distillation process of biosynthetic systems, achieving efficient separation of solvents, sesquiterpenes, and patchouli alcohol, resulting in high purity; the product aroma has a high matching degree with natural Indonesian essential oils; the process is mild throughout, can be stably scaled up from small-scale to ton-scale, and is low-cost. This invention provides a complete, efficient, and green technical solution for the industrialization of natural fragrances derived from synthetic biology.

The invention provides a composite peptide dietary supplement for improving damp-heat constitution as well as a preparation method, a preparation and application of the composite peptide dietary supplement, and belongs to the technical field of food biology. In the first aspect, the invention provides the composite peptide dietary supplement, and the composite peptide dietary supplement comprises the following raw materials: dandelion, poria cocos, lophatherum gracile, white hyacinth bean, coix seed, fresh rhizoma phragmitis, agastache rugosus, phaseolus calcaratus, honeysuckle and round cardamom; on the second aspect, the invention provides a preparation method of the composite peptide dietary supplement; and thirdly, the invention provides a preparation of the composite peptide dietary supplement. In the fourth aspect, the invention also provides application of the composite peptide dietary supplement and the preparation thereof in preparation of food or medicines suitable for people with damp-heat constitution.

The invention discloses zero-additive total-effect mouthwash and a preparation method thereof, and belongs to the technical field of oral care. The mouthwash comprises a natural substrate, a bacteriostatic and deodorant component, an anti-dental calculus, whitening and repairing component, a gingival maintenance component, a natural fragrance retention system and a natural solubilizer, purified water is added to 100%, and the pH value is adjusted to 5.5-6.5. All the components are from pure plants or natural minerals, do not contain alcohol, chemical preservatives, artificial pigments, artificial essence, SLS and chlorhexidine, and can be swallowed. The green tea extract, the pomegranate peel extract and the pogostemon cablin alcohol are compounded to realize synergistic bacteriostasis, and the nano zinc-loaded hydroxyapatite is combined to resist dental calculus and the papain is used for mildly whitening, so that multiple oral care effects are realized. The preparation method is simple in process and suitable for industrial production.

The invention discloses a nerve calming and sleep promoting incense, which has treatment and health care potential, and citrus plants such as citrus, bergamot, grapefruit and the like are considered to have soothing and relaxing effects; plants such as pepper, geranium and lavender are considered to have the characteristics of calming and promoting sleep; pogostemon cablin, cedar, vetiver grass and other plants may help relieve anxiety and pressure.

A cosmetic composition is provided, which comprises a carrier and a Patchouli stem extract, in particular an extract from exhausted Patchouli stems. This composition provides anti-oxidant, anti-elastase, anti-hyaluronase, and anti-tyrosinase activities.

This invention discloses a traditional Chinese medicine olfactory preparation for treating cough and asthma caused by phlegm obstructing the airways, and its preparation method, belonging to the field of traditional Chinese medicine technology. The olfactory preparation is made from the following raw materials in parts by weight: 6-15 parts of melon seeds, 1-6 parts of soapberry thorns, 3-10 parts of kelp, 6-15 parts of ginkgo leaves, 1-6 parts of coltsfoot flowers, 6-15 parts of goat horn, 1-6 parts of mulberry leaves, 3-12 parts of patchouli, 3-12 parts of cardamom, and 3-12 parts of peppermint. The preparation method includes: drying at 60℃ for 8 hours, mixing and pulverizing, stirring in both directions for 30 minutes, and then dispensing using a dispenser and sealing with gauze. This olfactory preparation is administered through nasal inhalation, utilizing the principle of "qi carrying qi, like qi seeking each other," directly reaching the lungs. It has the effects of resolving phlegm and relieving cough, softening and dispersing nodules, clearing obstructions and regulating qi, lowering qi and relieving asthma, and relieving spasms and astringing the lungs. It can be used for cough and asthma caused by phlegm obstructing the airways, airway congestion, phlegm and qi stagnation, and impaired lung function. The preparation process of this invention is simple, easy to use, non-irritating, safe and effective.

The application provides a compound essential oil and a preparation method, application and mosquito repellent thereof. The compound essential oil is prepared from raw materials including the following components by weight: 1-20 parts of mint, 1-10 parts of patchouli, 1-10 parts of duckweed, 1-10 parts of water calamus and 1-8 parts of rosemary. Compared with the prior art, the compound essential oil is composed of five aromatic Chinese herbal medicines, follows the principle of combination of monarch, minister, assistant and messenger, has the effects of dispelling mosquitoes and relieving itching, relieving superficies and removing dampness and aromatherapy and brain refreshing, and can effectively resist the symptoms of summer damp-heat stagnation of lung qi and normal operation of the spleen and stomach.

The invention relates to the field of cosmetics, in particular to a skin care composition containing pogostemon cablin, a preparation method of the skin care composition and cosmetics. The invention provides a skin care composition containing pogostemon cablin, which is prepared from the following components in percentage by mass: 10-25% of tea tree oil, 10-25% of pogostemon cablin, 10-25% of pogostemon cablin, 10-25% of pogostemon cablin, 10-25% of 15-30% of pogostemon cablin volatile oil; and 50 to 65% of evening primrose oil. According to the composition disclosed by the invention, all the components generate a synergistic effect, so that the inhibition effect on a propionibacterium acnes S21016 strain and staphylococcus aureus is improved; the anti-inflammatory effect is realized. The propionibacterium acnes and the staphylococcus aureus are closely related to the acnes; by inhibiting growth and reproduction of propionibacterium acnes and staphylococcus aureus bacteria, the effect of treating the acnes through bacteriostasis and sterilization is achieved.

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition provided by the invention comprises astragalus membranaceus, cinnamon, semen cassiae, lotus leaves, poria cocos, lophatherum gracile, malt, hawthorn, rose, pogostemon cablin, sophora flower, semen torreya and emblic leafflower fruit. The formula takes the effects of tonifying spleen and promoting diuresis, soothing liver and regulating qi, and removing food retention and dissolving turbidity as the core, and has multiple effects of promoting urination and relieving stasis. The traditional Chinese medicine composition provided by the invention can regulate and control abnormal signal pathways of fatty liver and atherosclerosis; the compound has no obvious inhibition effect on a hepatic cell line HepG2 and has an inhibition effect on a hepatic stellate cell line LX2; the obvious lipid-lowering effect is achieved on a HepG2 high-lipid model; liver fat accumulation and liver injury in a TAA-induced zebrafish fatty liver model can be remarkably improved.

This invention discloses a method for determining the content of a traditional Chinese medicine compound containing honeysuckle, isatis root, and scutellaria. The method includes the following steps: taking a test solution of the traditional Chinese medicine compound, a first reference solution, and a second reference solution for detection. The chromatographic conditions are as follows: using a chromatographic column packed with octadecyl-bonded silica gel; mobile phase A selected from one or more of acetonitrile, methanol, and tetrahydrofuran; and mobile phase B being an acidic aqueous solution, an alkaline aqueous solution, and / or a buffer salt aqueous solution. The traditional Chinese medicine compound includes honeysuckle, isatis root, scutellaria, indigo leaf, forsythia, platycodon, patchouli, and licorice. The reference standards are baicalin, ammonium glycyrrhizate, honeysuckle saponin B, and dipsacus saponin B. The detection method of this invention is simple, accurate, efficient, stable, precise, reproducible, convenient, and easy to master. It can effectively save energy and reduce analytical costs, while this technology is not disclosed in existing technologies.

The invention belongs to the technical field of water-resistant materials, and particularly relates to a water-resistant material and application of the water-resistant material in water insulation and preparation of an environment-friendly cinerary urn. Comprising the following raw materials in parts by weight: 60-90 parts of active soil, 8-12 parts of an insect prevention and sterilization composition and 30-45 parts of sand, the insect-preventing and sterilizing composition is prepared from 1.3 to 1.6 parts of herba pogostemonis powder, 1.1 to 2.2 parts of herba menthae powder, 1.2 to 1.5 parts of folium artemisiae argyi powder, 1.6 to 2.3 parts of fructus anisi stellati powder, 1.1 to 2.2 parts of flos caryophylli powder and 1.7 to 2.2 parts of camphor powder. Through improvement of a material formula and components, the material has sterilization and water insulation effects, the material is hardened after meeting water, and when the material is used as a cinerary casket filler, a better protection effect can be formed on the cinerary casket; by making the bone ash pot, the bone ash pot has a waterproof, insect-proof and hardened material or the bone ash pot, and when the pressure exceeds 0.8 MPa, the bone ash pot is broken and does not need to be degraded, so that the environment is protected.

The invention discloses a novel compound plant essential oil feed additive, which is prepared from the following raw materials: compound plant essential oil: origanum vulgare or thyme essential oil, cinnamon, clove, agastache rugosus, lemon, green tea and mosla chinensis or purple perilla essential oil. The synergistic effect of different components is utilized, the efficacy of the feed additive is comprehensively improved, and the comprehensive effects of enhancing animal immunity, promoting growth and improving the health condition are achieved; the preparation process is optimized, the stability of the compound plant essential oil is improved, the volatilization and oxidation loss in the feed processing, storage and transportation processes is reduced, and meanwhile, the effective release and absorption of the compound plant essential oil in animal digestive tracts are ensured; the palatability of the product is improved, the influence of strong odor or irritant components on the food consumption of animals is avoided, and the potential risk on the health of animals and human bodies is reduced by virtue of the safety of natural plant components; the problems of single effect and limited application in the prior art are solved, and an efficient and safe solution is provided for green breeding.

The invention discloses a pharmaceutical composition for rhinitis health care and respiratory tract circulation improvement and a preparation method thereof.The pharmaceutical composition is prepared from pogostemon cablin, osmanthus fragrans, geranium, wild chrysanthemum flowers, semen armeniacae amarae, astragalus membranaceus, pericarpium citri reticulatae, platycodon grandiflorum, mint and menthol through processing and liquefying, and through the synergistic effect of all the pharmaceutical ingredients, the pharmaceutical composition has the effects of inducing resuscitation with fragrance, dissolving turbidity and dredging resuscitation; the condition of unsmooth ventilation of the nose can be effectively improved, and uncomfortable symptoms such as nasal obstruction can be relieved; the spreading and descending of lung qi are regulated, and the normal physiological function of the respiratory tract is maintained; the whole resistance of the body and local qi and blood nourishing of the nose are enhanced, and repair and regeneration of nose tissues are promoted; the invasion of external heat toxin to the nose is resisted, and the inflammatory response is relieved. Long-term use of the nasal mask can significantly promote respiratory tract microcirculation, enhance the immune defense function of the nose, and effectively prevent occurrence and recurrence of nasal diseases.

This invention belongs to the field of traditional Chinese medicine, specifically relating to the preparation and application of a traditional Chinese medicine aromatherapy spray / ointment based on multiple effects. The composition of the aromatherapy is selected from at least eight of the following: peppermint, calamus, clove, patchouli, jasmine, atractylodes, artemisia, eupatorium, ligusticum, lavender, olive leaf, rose, mugwort, nutmeg, sophora japonica, honeysuckle, scutellaria, peppermint, and cinnamon. The extract of this herbal combination exhibits significant inhibitory effects on Staphylococcus aureus and Streptococcus epidermidis. Application surveys show it possesses significant pharmacological activities such as air freshening, mosquito repellent, antibacterial properties, and the ability to refresh the mind in the morning and calm the nerves at night. Furthermore, this herbal combination extraction greatly reduces the dosage of traditional Chinese medicine used, increasing the release efficiency and efficacy of the spray / ointment. The raw materials are inexpensive and readily available, the resulting herbal combination extract is easy to preserve, the production process is simple, the effects are obvious, the operation is simple and convenient, environmentally friendly and hygienic, easy to clean, and pollution-free.

The invention relates to the technical field of biological medicine, in particular to pogostemon cablin alcohol lipid cubic liquid crystal nanoparticles as well as a preparation method and application thereof. The pogostemon cablin alcohol lipid cubic liquid crystal nanoparticles comprise the following components: glyceryl monooleate, polyethylene glycol 400, poloxamer 407, D (+)-glucose and pogostemon cablin alcohol. The pogostemon cablin alcohol lipid cubic liquid crystal nanoparticle is of a core-shell structure, a shell is of a skeleton structure jointly formed by the glyceryl monooleate, the polyethylene glycol 400, the poloxamer 407 and the D (+)-glucose, and a core is the pogostemon cablin alcohol. The patchouli alcohol lipid cubic liquid crystal nanoparticles are good in in-vitro stability, have a slow release effect compared with free drugs, and have good development and application prospects in the field of chemotherapeutic intestinal injury treatment.

The invention belongs to the technical field of medicines, and particularly relates to a multi-dosage-form skin care product composition containing dendrobium nobile, radix polygonati officinalis, radix ophiopogonis, pogostemon cablin and liquorice extracts and a preparation method of the multi-dosage-form skin care product composition. The skin care product composition is a plant extract composition, and the plant extract composition is extracted from the following five raw materials in parts by weight: 4-10 parts of dendrobium nobile, 4-10 parts of radix polygonati officinalis, 2-6 parts of radix ophiopogonis, 1-4 parts of pogostemon cablin and 1-4 parts of liquorice. In the composition disclosed by the invention, the dendrobium nobile is rich in active ingredients such as polysaccharide, and has remarkable effects of moisturizing and enhancing skin immunity; the main functional component of polygonatum odoratum is a flavonoid compound, so that the polygonatum odoratum has good anti-oxidation and anti-inflammatory performance; the radix ophiopogonis has the advantage of saponin components, and has a key effect of repairing a skin barrier; volatile oil components of pogostemon cablin can play antibacterial and deodorizing effects; and glycyrrhizic acid and other components in the liquorice can further synergistically enhance the anti-inflammatory effect and the like.

This invention provides a traditional Chinese medicine preparation for treating or relieving functional constipation in children, belonging to the field of traditional Chinese medicine technology. The preparation is made from raw Atractylodes macrocephala, banana root, Citrus reticulata, mulberry, Lophatherum gracile, Hovenia dulcis leaf, Ziziphus jujuba leaf, Pogostemon cablin, Citrus reticulata peel, Torreya grandis seed, and licorice. This traditional Chinese medicine preparation significantly increases the number of fecal particles in constipation model rats over 24 hours, increases fecal water content, and improves intestinal propulsion rate, thus improving intestinal peristalsis. In clinical observation, this traditional Chinese medicine preparation effectively relieves the core symptoms of children, shortens the interval between defecation, softens stool, and alleviates straining during defecation. It also improves accompanying symptoms such as abdominal distension and halitosis. After the course of treatment, bowel regularity returns, and there is no significant recurrence during follow-up, providing a new option for the clinical treatment of functional constipation in children.

The invention provides several kinds of natural saccharification leavening agents and a method for brewing yellow rice wine in a koji-free mode through the natural saccharification leavening agents. The natural saccharification leavening agent is biomass which is harvested from the nature, is not subjected to artificial inoculation and cultivation and has a saccharification or / and fermentation effect; comprising green seedlings of grains, ears of grains in a milk-ripe stage, pine pollen, bee pollen, flowers of edible flowers in a full-bloom stage, part of green vegetables and green edible aromatic plants, part of medicinal and edible plants, medicinal plants and the like. Such as wheat seedlings, green wheat kernels, pine pollen, corn bee pollen, rape bee pollen, kale, peanut seedlings, basil, rosemary, roses, sweet-scented osmanthus, mint, agastache rugosus, lotus leaves, mulberry leaves, leonurus, grape leaves and the like; the raw materials of the natural saccharification leavening agent are easy to obtain, various in variety and convenient to process, the brewed yellow wine can have faint scent, strong fragrance, medicine fragrance and flower fragrance at the same time through reasonable combination, the wine body taste is harmonious, fresh and mellow, the taste is pleasant, and meanwhile multiple health preserving and health care functions are achieved; the natural saccharification leavening agent can be used for grain fermentation at high temperature (about 35 DEG C) without rancidification, so that the stability of a wine brewing process is remarkably improved, and the failure probability of wine brewing is greatly reduced.

The invention discloses health-preserving tea with multiple effects and a preparation method thereof. The health-preserving tea comprises the following raw materials in parts by weight: 5-15 parts of honeysuckle, 5-15 parts of radix isatidis, 3-10 parts of pogostemon cablin, 5-15 parts of codonopsis pilosula, 10-20 parts of astragalus membranaceus, 5-10 parts of medlar, 5-15 parts of poria cocos, 3-10 parts of polyporus umbellatus, 3-8 parts of elecampane, 5-15 parts of salvia miltiorrhiza, 5-15 parts of radix puerariae, 5-15 parts of radix rehmanniae and 3-10 parts of radix achyranthis bidentatae. The health-care efficacy is remarkably improved through the multi-target synergistic effect, immune-metabolic axis synergistic regulation is achieved, the physiological homeostasis is reconstructed through blood-yin co-tonifying, a double-way drainage and detumescence mechanism is achieved, and the time-space stepwise effect of activating blood circulation and removing blood stasis is achieved.

The application relates to the technical field of plant genetic engineering, and particularly discloses application of a patchouli alcohol synthase PcENO3 in preparation of a product for regulating patchouli alcohol biosynthesis. The application first discovers that the patchouli alcohol synthase PcENO3 is an interaction protein of the patchouli alcohol synthase, and proves that the patchouli alcohol synthase PcENO3 interacts with the patchouli alcohol synthase PcPTS, and can effectively improve the in-vitro enzyme catalytic activity of the PcPTS and the content of the patchouli alcohol. Cloning of the protein coding gene and biological function verification have important theoretical and practical significance for the molecular mechanism research of the interaction protein in regulating patchouli alcohol biosynthesis, and particularly for biosynthesis of the patchouli alcohol through a metabolic pathway or yeast fermentation engineering.

The present invention relates to new classes of odorous 3-(2-methylenealkoxy)alkanenitrile derivatives of formula (I) which are useful as fragrance or flavor materials in particular in providing dry, woody, dusty, earthy, and / or patchouli notes together with optional coriander, aldehydic, citrus, mandarin, pear, cinnamon, and / or petal floral-like notes to perfume, aroma or deodorizing / masking compositions.

The application relates to the technical field of traditional Chinese medicine compositions, in particular to a mosquito-repelling sachet and a preparation method thereof. The mosquito-repelling sachet comprises the following raw materials in parts by weight: 60-80 parts of artemisia argyi, 40-60 parts of pachouli, 20-40 parts of rhizoma acori graminei, 20-40 parts of pterocephalus totatus, 3-5 parts of peppermint oil, 1-3 parts of clove oil, 3-5 parts of rosemary oil and 1-3 parts of lavender oil. The preparation method of the mosquito-repelling sachet is as follows: S1: taking the prepared artemisia argyi, pachouli, rhizoma acori graminei and pterocephalus totatus according to the parts by weight, and low-temperature vacuum drying until the moisture content is lower than 15%; S2: putting the dried medicinal materials into a mixing machine, firstly stirring and mixing in the clockwise direction, pausing for a period of time, and then stirring and mixing in the counterclockwise direction; S3: crushing the medicinal material mixture into coarse powder and sieving; S4: spraying the sieved coarse powder with the peppermint oil, clove oil, rosemary oil and lavender oil and uniformly mixing; S5: taking the quantitative mixed coarse powder, putting the coarse powder into the sachet and sealing, and placing the sachet in a closed cool place to obtain the mosquito-repelling sachet.

The invention provides a Huoxiang Zhengqi direct-taking taste-masking composition and a preparation method, and belongs to the technical field of pharmaceutical preparations, the Huoxiang Zhengqi direct-taking particle composition comprises the following components by weight: 60-100 parts of a traditional Chinese medicine composition, 1-5 parts of a taste regulator, 1-10 parts of an anti-sticking agent, 1-5 parts of a plasticizer, and 10-50 parts of a polymer coating material; the traditional Chinese medicine composition comprises the following raw materials: pogostemon cablin, folia perillae acutae, radix angelicae, pericarpium arecae, poria cocos, rhizoma atractylodis macrocephalae, pericarpium citri reticulatae, mangnolia officinalis, raw pinellia ternate, platycodon grandiflorum and liquorice. The prepared Huoxiang Zhengqi direct-taking taste-masking composition is remarkable in taste-masking effect, the compliance is improved, the bad taste is completely masked through the powder coating technology, the taste-masking composition is combined with other flavoring agents, the cool and sweet taste can be provided, and the medication compliance of a patient is remarkably improved.