The present application relates to a
nicotine pellet composition, a
nicotine pellet pouch and a preparation method thereof. The
nicotine pellet composition comprises nicotine, a blank pellet core, a binder, a sweetener, a pH
regulator,
cellulose and
cellulose derivatives, a high-molecular
coating material, a
lubricant, a flavoring agent and a
solvent. The blank pellet core is loaded with the nicotine, and the high-molecular
coating material forms a single layer or multiple
layers of
drug loading or
coating on the blank pellet core. When the high-molecular coating material forms multiple
layers of
drug loading or coating, it comprises, from inside to outside, a separation layer, a
drug-containing layer, a protective layer and a drug-loading layer. The present application provides a nicotine pellet composition and a nicotine pellet pouch with good fluidity, stable nicotine release and stable
aroma release, which can be used for the treatment of
smoking cessation or nicotine dependence.