65 results about "Triethyl citrate" patented technology

The application provides a bupropion hydrochloride sustained-release tablet and a preparation method, and belongs to the technical field of pharmacy. The pharmaceutical composition contains 150 parts of bupropion hydrochloride, 122.5-157.5 parts of glycerin monostearate, 17.5-22.5 parts of triethyl citrate, 68-104 parts of microcrystalline cellulose and 2-6 parts of magnesium stearate, wherein the bupropion hydrochloride raw material and the glycerin monostearate and the triethyl citrate are prepared into a solid dispersion through a hot melt extrusion process. The application provides a bupropion hydrochloride sustained-release tablet which is stable in drug release, slow in growth of related substances, does not need to be coated and can be taken and eaten, and a preparation method.

The invention belongs to the technical field of biological medicine, and particularly relates to a ganoderma lucidum polysaccharide sustained-release liver protection preparation and a preparation method thereof.The preparation comprises a pellet, the pellet comprises a pellet core, a medicine layer, an inner sustained-release layer and an outer mucous membrane attachment enteric-coated composite layer, and the pellet core is coated with the medicine layer, the inner sustained-release layer and the outer mucous membrane attachment enteric-coated composite layer in sequence; the medicine layer contains high-purity ganoderma lucidum polysaccharide; the inner slow-release layer is composed of ethyl cellulose, triethyl citrate and polyethylene glycol 4000; the outer mucous membrane attachment enteric composite layer is formed by compounding chitosan and a pH sensitive polymer, preferably, an in-situ network structure is formed through calcium ion crosslinking, and the outer mucous membrane attachment enteric composite layer has the enteric function and the mucous membrane attachment function. The invention aims to solve the problems that the existing ganoderan preparation is too fast in release, large in blood concentration fluctuation and short in action time. Through the synergistic effect of the structures, the ganoderma lucidum polysaccharide sustained-release liver protection preparation is stable in stomach, targeted in intestinal tract release and retained in mucous membranes, the sustained-release effect of 12 h or above is achieved, and the bioavailability and the liver protection curative effect are remarkably improved.

A filter material is shown comprising a cellulose fiber-based substrate, an additive and an adhesion promoter, wherein the mass ratio of the additive and the adhesion promoter is at least 1:3 and at most 2:1, and the additive and the adhesion promoter together constitute at least 3% and at most 40% of the mass of the cellulose fiber-based substrate, wherein the additive is triethyl citrate, triacetin or a mixture of these substances, and wherein the adhesion promoter is selected from the group consisting of ethanediol, propanediol, butanediol, pentanediol and glycerin diacetate or mixtures thereof.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating pleural effusion and peritoneal effusion and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, 10-50 parts of traditional Chinese medicine extract, 30-70 parts of filler, 5-20 parts of enteric coating material, 5-15 parts of HPMC, 0.5-2 parts of triethyl citrate and 0.25-1.5 parts of magnesium stearate; poria cocos, polyporus umbellatus, rhizoma alismatis, astragalus membranaceus, curcuma zedoary, cassia twig, oldenlandia diffusa, sculellaria barbata, semen coicis and traditional Chinese medicine extracts are used as cores, the stability of volatile drugs is improved through an inclusion technology, and the volatile drugs are entrapped in a pH intelligent response type enteric coating material composed of aromatic ring-containing vinyl monomers, ethyl acrylate, DMAEMA and MAA. The traditional Chinese medicine preparation has the synergistic effect of efficiently inducing diuresis, activating blood circulation and eliminating tumors and enteric-coated long-acting directional delivery, and is suitable for patients with pleural effusion and peritoneal effusion, especially malignant effusion.

Described herein are pharmaceutical compositions comprising extended-release pellets and optionally delayed release pellets, wherein each of the extended-release pellets and each of the delayed release pellets comprises a drug pellet and an outer coating; the outer coating of the extended-release pellets is an extended-release outer coating; the outer coating of the delayed release pellets is a delayed release outer coating; the outer coating of the extended-release pellets is an extended-release outer coating; the outer coating of the delayed release pellets is a delayed release outer coating; the drug pellet comprises about 15 wt.% to about 25 wt.% ibudilast, about 60 wt.% to about 70 wt.% sugar sphere, about 5 wt.% to about 10 wt.% hydroxypropyl methylcellulose, and about 4 wt.% to about 8 wt.% silicon dioxide; the extended-release outer coating comprises about 20 wt.% to about 55 wt.% ethyl cellulose, about 20 wt.% to about 55 wt.% hydroxypropyl methylcellulose, about 1 wt.% to about 4 wt.% triethyl citrate, and about 20 wt.% to about 25 wt.% talc, wherein the weight percentages of ethyl cellulose, hydroxypropyl methylcellulose, triethyl citrate, and talc are based on total weight of the extended-release outer coating; and the delayed release outer coating comprises about 55 wt.% to about 65 wt.% copolymer of methacrylic acid and ethyl acrylate, about 3 wt.% to about 9 wt.% triethyl citrate, and about 25 wt.% to about 35 wt.% talc, wherein the weight percentages of the copolymer of methacrylic acid and ethyl acrylate, triethyl citrate, and talc are based on total weight of the delayed release outer coating.

The invention relates to the technical field of cigarette filter stick paper, in particular to paper filter stick paper for cigarettes and a preparation method thereof, and the paper filter stick paper comprises the following raw materials in parts by weight: 250-300 parts of water, 35-40 parts of a first base material, 30-35 parts of a second base material, 6-8 parts of glycerol, 2-3 parts of triethyl citrate, 8-12 parts of aluminum hydroxide, 2-4 parts of citric acid and 8-12 parts of an additive. According to the invention, the corn starch selectively oxidized by sodium periodate is used as a first base material, and the bamboo pulp fiber subjected to fine treatment is used as a second base material, so that the traditional cellulose acetate is completely replaced, the biodegradation rate of the filter stick in the environment is obviously accelerated, and the pollution problem caused by material inertia is fundamentally solved.

The invention provides a preparation method of a waterborne polyurethane emulsion without a volatile solvent, and belongs to the technical field of material preparation. The preparation method comprises the following steps: taking polyether glycol, hexamethylene diisocyanate and 2, 2-dimethylolpropionic acid (DMPA) as raw materials, taking dibutyltin dilaurate as a catalyst, carrying out one-pot polymerization in a specific reaction medium triethyl citrate, and carrying out pH regulation and emulsification to obtain the stable waterborne polyurethane emulsion. The prepared emulsion can form a transparent polyurethane material with good mechanical properties after being dried, the boiling point of triethyl citrate exceeds 250 DEG C, and the transparent polyurethane material has good stability in daily life. According to the preparation method of the waterborne polyurethane, no volatile solvent exists in the whole process, the adopted functional components are safe in source, the treatment process is simple and convenient, and a thought can be provided for development of synthesis of a green solvent-free waterborne polyurethane solution so as to meet the requirement of green sustainable development.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to an acetate fiber thermoplastic coating film as well as preparation and application thereof. The cellulose acetate thermoplastic coating film is prepared by thermoforming cellulose acetate, triethyl citrate and polyethylene glycol which are uniformly mixed as raw materials. The preparation process is high in automation and scale degree, low in environment and equipment requirements, green and environment-friendly, capable of reducing loss and suitable for industrial production. The sustained and controlled release preparation prepared from the cellulose acetate fiber thermoplastic coating film has a good sustained and controlled release effect, and a new coating direction is provided for preparation of the sustained and controlled release preparation.

The invention discloses a bio-based degradable wrapping film and a preparation method thereof in the field of green logistics and environment-friendly packaging. The wrapping film is prepared from polylactic acid, poly (butylene succinate), triethyl citrate, an antioxidant, calcium stearate and two novel inorganic modified compounds. Wherein the zirconium phosphate-sodium carboxymethyl cellulose intercalation compound constructs an organic-inorganic hybrid structure through alkaline intercalation, so that the dispersity and interfacial compatibility of the filler are effectively improved; the lanthanum titanate-zinc oxide core-shell nano hybrid is prepared by combining a solvothermal method with a urea precipitation process, has regular core-shell morphology, can synergistically enhance mechanical properties, regulate and control degradation rate, and endows antibacterial and ultraviolet shielding functions. The wrapping film prepared by melt blending and film blowing processes has high tensile strength, excellent ductility, good transparency and controllable compost degradability.

The invention discloses a preparation method of composite roasted peanut essence, which belongs to the technical field of essence, and comprises the following steps: preheating peanut oil and caprylic / capric triglyceride; the preparation method comprises the following steps: dissolving ethyl maltol, vanillin, methyl cyclopentenolone, 2, 3, 5-trimethylpyrazine and 2-acetylpyrazine; vanillin propylene glycol acetal, isovaleraldehyde propylene glycol acetal, triethyl citrate, delta-decalactone, delta-dodecalactone and 5-hydroxyethyl-4-methylthiazole are fused to obtain a mixture; dispersing the roasted peanut extract; 2, 3-dimethylpyrazine, 2-methoxyl-5-methylpyrazine and 4-methylthiazole are fused, and then the mixture is subjected to a reaction; the preparation method comprises the following steps: fusing cocaal, dimethyl sulfide, 2-ethyl-3, 5, 6-dimethylpyrazine, 2, 3, 5, 6-tetramethylpyrazine, 2-methylpyrazine, 2-acetylpyridine, 2-methoxy-3. 5. 6-isopropyl pyrazine, 2-methylthio-3-methylpyrazine, isovaleric acid, 1-octylene-3-alcohol, 5-methylfurfural and 3, 4-dimethyl-1, 2-cyclopentanedione; standing is performed; filtering is performed; the fragrance of the roasted peanuts is closer to that of the roasted peanuts which are just taken out of a furnace, and the natural flavor of the roasted peanut essence is increased.

To provide an oral composition that contains an azulene compound while effectively inhibiting color change of the composition itself.SOLUTION: An oral composition comprising the following components (A) and (B): (A) one or two or more azulene compounds selected from azulene, azulene sulfonic acid and a salt thereof, and guaiazulene; and (B) one or two or more fragrance components selected from thymol, terpinolene, β-ionone, nerol, carvone, anisaldehyde, vanillin, cis-3-hexenone, menthyl lactate, benzyl alcohol, diethyl malonate, isopulegol, triethyl citrate, and citronellol.SELECTED DRAWING: None

One embodiment of the present invention aims to provide a palbociclib tablet in which the formation of acetyl adducts of palbociclib is suppressed. [Solution] According to one embodiment of the present invention, a palbociclib-containing tablet is provided, comprising a core tablet containing palbociclib or a pharmaceutically acceptable salt thereof, and a film coat layer covering the core tablet, wherein the film coat layer contains an acetyl group-free plasticizer. The acetyl group-free plasticizer may be at least one selected from the group consisting of triethyl citrate, polyvinyl alcohol, polyethylene glycol, and hydroxypropyl cellulose.

The invention relates to the technical field of plant protection, in particular to a timed release pesticide and a preparation method and application thereof. The timed release pesticide comprises a core material and a coating coated on the surface of the core material, the core material is a pyrazosulfuron-pretilachlor effervescent tablet; the coating is prepared from eudragit, ethyl cellulose and triethyl citrate. Compared with pyrazosulfuron-pretilachlor effervescent tablets, the timed release pesticide disclosed by the invention has the advantages that the proportion of a coating material can be adjusted according to needs, the release time can be controlled, rice transplanting or mechanical transplanting and pesticide application can be synchronously carried out, labor saving is realized, and the timed release pesticide has a good control effect on gramineous weeds and broadleaf weeds; moreover, phytotoxicity to rice caused by application of pyrazosulfuron-pretilachlor effervescent tablets during transplanting is avoided.

An insect repellent composition for animals is disclosed. The insect repellent composition includes plant-based active ingredients and inert ingredients. The active ingredients include geraniol, clove oil, peppermint oil, and rosemary oil. The inert ingredients include mineral oil, isopropyl myristate, isopropyl alcohol, oleic acid, lauric acid, triethyl citrate, ethyl lactate, and vanillin.

An environmentally-clean aqueous-based fire extinguishing biochemical liquid concentrate to be mixed with a proportioned quantity of water, to produce a fire extinguishing water stream that produces good immediate extinguishing effects when applied to extinguish a burning or smoldering fire, and good long-term fire inhibiting effects when being proactively applied to protect combustible surfaces against the threat of fire. The environmentally-clean aqueous-based fire extinguishing biochemical liquid concentrate includes: a dispersing agent realized in the form of a quantity of water, for dispersing potassium ions dissolved in water; a fire inhibiting agent in the form of at least one alkali metal salt of a nonpolymeric saturated carboxylic acid, specifically potassium citrate, for providing potassium ions dispersed in the quantity of water when the potassium citrate is dissolved in the quantity of water; and a dispersing agent in the form of triethyl citrate, an ester of citric acid, for dispersing the potassium ions in the quantity of water, and lowering the surface tension of the liquid solution formed when the potassium citrate is dissolved in the quantity of water, forming of a fire extinguishing liquid solution, for mixing with a proportioned amount of water, to produce a fire extinguishing water stream having good immediate extinguishing effects when applied to extinguish a burning or smoldering fire, and good long-term fire inhibiting effects when applied proactively to protect combustible surfaces against the threat of fire ignition and flame spread of an incident fire.

An environmentally-clean fire inhibiting liquid biochemical composition for application on combustible surfaces to inhibit fire ignition and flame spread in the presence of fire. The environmentally-clean fire inhibiting liquid biochemical composition including a dispersing agent realized in the form of a quantity of water, for dispersing metal ions dissolved in water; a fire inhibiting agent in the form of at least one alkali metal salt of a nonpolymeric saturated carboxylic acid, for providing metal ions dispersed in the water when the alkali metal salt of a nonpolymeric saturated carboxylic acid is dissolved in the quantity of water; and a coalescing agent in the form of an organic compound containing three carboxylic acid groups, or salt / ester derivatives thereof, specifically triethyl citrate (TEC), an ester of citric acid, for dispersing and coalescing the metal ions when the fire inhibiting liquid composition is applied to combustible surfaces to be protected against fire, while water molecules in the water evaporate to the environment during drying, and the metal ions cooperate to form thin alkali metal salt crystalline coatings on the combustible surfaces. The alkali metal salt of nonpolymeric saturated carboxylic acid may be selected from the group consisting of: alkali metal salts of citric acid; alkali metal salts of oxalic acid; alkali metal salts of gluconic acid; and alkali metal salts of tartaric acid. The alkali metal salt of nonpolymeric saturated carboxylic acid may be selected from the group consisting of the alkali salt of lithium, the alkali salt of sodium, the alkali salt of potassium, the alkali salt of cesium and the alkali salt of rubidium. Preferably, the alkali metal salt of nonpolymeric saturated carboxylic acid is an alkali salt of potassium, namely tripotassium citrate (TPC).

The invention discloses a preparation method of an antibacterial fiber, the antibacterial fiber and a storage box containing the antibacterial fiber, and relates to the technical field of functional fiber materials.The preparation method is technically characterized by comprising the following steps that S1, 2-4 parts by weight of nanoscale titanium dioxide, 1-3 parts by weight of nanoscale zinc oxide, 2-5 parts by weight of triethyl citrate, 1-3 parts by weight of polyethylene glycol 400 and 89-94 parts by weight of deionized water are mixed, and a mixture is obtained; performing high-speed shearing dispersion and ultrasonic treatment to obtain a uniform and stable activating agent pretreatment solution; s2, immersing a polymer slice into the activating agent pretreatment liquid obtained in the step S1 for constant-temperature impregnation, then taking out the polymer slice, and performing vacuum drying to obtain the polymer slice subjected to activation pretreatment; through a unique non-antibacterial activator and a synergistic process, a stable functional layer is constructed in the fiber, and the fiber is endowed with intrinsic antibacterial property. The antibacterial property still keeps a higher level after being washed for more than or equal to 100 times.

This invention provides a halogen-free no-clean flux and its preparation method, belonging to the field of flux technology. The method includes the following steps: Step S1: L-histidine and itaconic acid are compounded and reacted, then concentrated under reduced pressure, dried, pulverized, and sieved to obtain a histidine-itaconic acid composite activator; Step S2: Polyvinyl butyral is added to a mixed solvent of isopropanol, anhydrous ethanol, and dipropylene glycol methyl ether for wetting, dispersion, and dissolution, followed by the addition of hydrogenated rosin and triethyl citrate to obtain a resin-based solution; Step S3: The histidine-itaconic acid composite activator is added to a mixed system of deionized water, isopropanol, and anhydrous ethanol to obtain an activator solution; Step S4: The activator solution is slowly added to the resin-based solution, defoamed, filtered, and cured to obtain a halogen-free no-clean flux. This invention achieves the goals of good soldering activity, controllable residue, high system uniformity, and good storage stability in halogen-free no-clean flux.

The present invention relates generally to methods and compositions useful for concealing skin imperfections. The method can include applying a topical composition to facial skin, for example skin under the eye. The composition can include Glycyrrhiza glabra root extract, disteardimonium hectorite, trisiloxane, triethyl citrate, cetyl dimethicone, and cetyl PEG / PPG-10 / 1 dimethicone.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine pill coating with high humidity resistance and a preparation method thereof. The technical scheme adopted by the invention is characterized by comprising the following components in parts by weight: 50-60 parts of ethyl cellulose (with the viscosity of 18-22 mPas), 10-15 parts of hydroxypropyl methyl cellulose (with the viscosity of 100 mPas), 1-3 parts of nano silicon dioxide, 13-16 parts of microcrystalline cellulose and 11-14 parts of triethyl citrate.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses a traditional Chinese medicine composition with liver protecting and nourishing effects and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition with the liver protecting and nourishing effects is prepared from the following raw materials: chitosan quaternary ammonium salt, 4, 4 '-dihydroxyazobenzene, acrylic resin S100, mesoporous silica nanoparticles, triethyl citrate, polyethylene glycol, a radix puerariae extract, a hovenia dulcis thunb extract, an emblic leafflower fruit extract, pseudo-ginseng powder, microcrystalline cellulose, polyvinylpolypyrrolidone and magnesium stearate. The traditional Chinese medicine composition disclosed by the invention has an enzyme-pH dual response mechanism, ensures that the medicine is only released in the colon, solves the gastric stimulation problem of medicine components such as emblic leafflower fruit and the like, effectively improves the bioavailability of active components and realizes stable and lasting blood concentration due to the absorption promotion effect of colon-targeted combination with chitosan quaternary ammonium salt. The preparation method of the traditional Chinese medicine composition is advanced, efficient and controllable, and the superiority and stability of product quality are guaranteed.

The application relates to the technical field of high polymer materials, and particularly discloses super-transparent glue and BOPP (Biaxially-oriented polypropylene) lightening film containing the glue. The super-transparent glue is composed of butyl acrylate, isooctyl acrylate, triethyl citrate, vinyl acetate, octadecyl trimethyl ammonium chloride, methyl oleate, 3-methoxy propylamine, an initiator and a solvent. The application has the advantage of improving the transparency of the glue.

The invention discloses a green and safe essence stabilizer as well as a preparation method and application thereof. The green and safe essence stabilizer is prepared from the following components in percentage by mass: 5-15% of diethylaminohydroxybenzoyl hexyl benzoate, 5-15% of diethylaminohydroxybenzoyl hexyl benzoate, 5-15% of diethylaminohydroxybenzoyl hexyl benzoate and the balance of water. 6% to 18% of ethylhexyl methoxycinnamate; 1%-10% of isooctyl salicylate and 10%-40% of an antioxidant; and the balance of solvent. The antioxidant is prepared by compounding butylated hydroxytoluene and butylated hydroxyanisole according to a certain proportion, and the solvent is prepared by compounding isopropyl myristate and triethyl citrate according to a mass ratio of (30-50): 1 with the other three components, so that the colored daily chemical essence is not easy to discolor and not easy to change flavor for at least 2 months under UV light, and meanwhile, relatively good clarity is kept; and the problem of pain points in the industry all the time is solved.

A smoking article filter and a smoking article are provided. The smoking article filter includes lyocell tow containing lyocell fibers and a phenol-reducing substance dispersed in the lyocell tow, the phenol-reducing substance including triethyl citrate (TEC), and the content of the triethyl citrate per mm of the lyocell tow is 0.11 mg to 1.85 mg.

An environmentally-clean fire inhibiting liquid biochemical composition for application on combustible surfaces to inhibit fire ignition and flame spread in the presence of fire. The environmentally-clean fire inhibiting liquid biochemical composition includes: a dispersing agent realized in the form of a quantity of water, for dispersing potassium ions dissolved in the water; a fire inhibiting agent realized in the form of potassium citrate, for providing potassium ions dispersed in the water when the potassium citrate is dissolved in the water; and a coalescing agent realized in the form of triethyl citrate, an ester of citric acid, for dispersing and coalescing the potassium ions when the fire inhibiting liquid composition is applied to a combustible surfaces to be protected against fire ignition and flame spread, and while water molecules in the water evaporate during drying, the potassium ions cooperate to form a thin potassium salt crystalline coating on the treated combustible surface that proactively protects the treated combustible surfaces against fire ignition and flame spread, in the presence of fire.

Disclosed is a rinse-free cleansing composition. The cleansing composition comprises a solute part in an amount ranging 1.13% w / w to 12.25% w / w with respect to a total weight of the rinse-free cleansing composition. Herein, the solute part comprises, a surfactant composition in an amount ranging 0.02% w / w to 1.2% w / w with respect to the total weight of the rinse-free cleansing composition, at least one humectant, at least one buffer agent, a preservative composition, and triethyl citrate; and a solvent part in amount ranging 87.75% w / w to 98.87% w / w with respect to the total weight of the rinse-free cleansing composition.

The application discloses a preparation method of a tea polyphenol-based antibacterial material and application of the antibacterial material in tobacco extract liquid. The antibacterial material comprises a core material and a pH response coating layer coated on the surface of the core material. The core material comprises the following components in parts by mass: tea polyphenol 10-40%, ethyl cellulose 30-50%, microcrystalline cellulose 20-40% and propylene glycol 5-10%. The pH response coating layer comprises hydroxypropyl methyl cellulose phthalate, triethyl citrate and talc powder in a mass ratio of 100:(12-18):(15-25). The mass ratio of the core material to the pH response coating layer is 100:(10-15). The application realizes self-catalytic closed-loop slow release of tea polyphenol by means of nano-pore diffusion and pH response dissolution controlled release mechanism, relies on pH change of the system, can efficiently inhibit microbial proliferation in the tobacco extract liquid, supports tablet recycling and reuse, and provides a safe, green, long-acting and stable antibacterial solution for the tobacco extract liquid.

The invention discloses a degradable composite film based on modified straw microfibrillated cellulose and a preparation method of the degradable composite film, and relates to the field of preparation of degradable composite films. Comprising the following steps: preparing a suspension of modified straw microfibrillated cellulose through carboxylation modification and shearing treatment; heating the suspension of the modified straw microfibrillated cellulose, sequentially adding an acidic solution of chitosan, a mixed solution of triethyl citrate and pre-emulsified rosin glyceride and citric acid, and fully mixing and reacting to obtain a uniform film-forming composite solution; carrying out low-temperature concentration on the composite liquid, standing for defoaming, casting on a flat plate, and carrying out gradient heating drying; and after drying is completed, the thin film is peeled off and cooled after hot pressing treatment, and the composite thin film is obtained. The degradable composite film is prepared from the waste straw, and the composite film has good mechanical strength, flexibility and water resistance at the same time.

A perfumed composition in a solid or semi-solid form, where the composition includes from 5 to 40% by weight of the total weight of the perfume composition, and from 10 to 15% by weight of the total weight of the trihydroxystearin composition. The composition includes a solvent, preferably triethyl citrate. One or more embodiments relate to the field of perfumes and perfumed compositions. It finds advantageous application in the field of fine perfumery, cosmetics, hygiene products to be rinsed off or not, and home fragrances or indoor deodorisers or air fresheners.

The invention discloses a degradable pigment and a preparation method thereof, and belongs to the technical field of pigment preparation. The preparation method comprises the following steps: adding polylactic acid, a natural pigment, a flame retardant and modified sodium alginate into a high-speed dispersing agent machine, dispersing and mixing for 20-30 minutes, then adding triethyl citrate and ethylene bisstearamide into a dispersion system, stirring and mixing for 10-20 minutes, and drying to obtain the degradable pigment. The degradable pigment disclosed by the invention has the advantages of degradability, favorable weather resistance and favorable flame retardancy.