178 results about "Long lasting" patented technology

The disclosure provides method of treating cancer in a patient in need thereof, comprising safely and efficaciously administering to the patient PLX038, a long lasting-PEGylated prodrug of the topoisomerase I inhibitor. The disclosure further provides combination therapies of PLX038 with inhibitors of the DNA damage response (DDR).

A circadian rhythm-based time-sharing repair formula and use thereof. A day composition focuses on anti-oxidation, stress resistance and energy metabolism to resist oxidative damage and enhance day vitality and provide long-lasting antioxidation protection. A night composition focuses on DNA repair, anti-inflammation and nerve relaxation to promote cell regeneration and repair and continuously support night repair. The composition of the day composition and the night composition designed according to the circadian rhythm of human metabolism causes the corresponding activities to take effect at the best time, and components are designed to cooperate with each other according to different physiological needs during the day / night, which can greatly improve the anti-aging effect.

The disclosure provides method of treating cancer in a patient with ATM-deficient or ATR-deficient tumors, comprising safely and efficaciously administering to the patient PLXO38, a long lasting-PEGylated prodrug of the topoisomerase I inhibitor. The disclosure further provides combination therapies of PLXO38 with inhibitors of the DNA damage response (DDR).

The invention relates to a composition with a permeation enhancing effect and application thereof. The composition is prepared from the following components in parts by weight: 10 to 15 parts of ethoxydiethylene glycol, 10 to 15 parts of isosorbide dimethyl ether, 5 to 10 parts of folium artemisiae argyi extract and 1 to 6 parts of tea tree essential oil. According to the permeation enhancing composition, traditional azone easy to sensitize and ethyl alcohol easy to cause stimulation are abandoned, the efficient, safe and lasting permeation effect is finally achieved, and the permeation enhancing composition meets the high-activity component delivery requirement of cosmetics.

The invention discloses a protective base film for a polaroid and a preparation method of the protective base film, and belongs to the technical field of optical display equipment protective films. The protective base film comprises an antistatic PET base material layer and a self-adhesive layer, the antistatic PET base material layer is prepared by blending optical-grade PET slices and antistatic master batches, the master batches are prepared by taking ionic liquid dihydric alcohol as a comonomer, and the base film is endowed with lasting and stable intrinsic antistatic performance; the self-adhesive layer is formed by melting and blending a polyurethane acrylate prepolymer, a modified montmorillonite filler, other matrix materials and auxiliaries according to a specific ratio and carrying out an online UV curing process. Through innovative material design and an integrated forming process, the prepared protective base film has excellent optical transparency, lasting antistatic property, appropriate bonding strength, clean stripping property and outstanding damp-heat aging resistance, the comprehensive performance is remarkably superior to that of a traditional gluing protective film, and the production process is more environment-friendly and efficient.

The invention provides an inner hole plasma spraying high-bonding-strength bonding layer and Y2O3 coating material and a preparation technology thereof. The bonding layer comprises a middle transition layer formed after Si and C on the surface of a graphite matrix are subjected to a chemical reaction. The inner hole plasma spraying high-bonding-strength bonding layer provided by the invention is composed of a silicon carbide transition layer generated by in-situ reaction of molten silicon and carbon on the surface of a graphite matrix, and can form a Si-O-M bridged bond with a subsequent ceramic coating, so that interface bonding is converted into chemical bonding from mechanical anchoring, and the bonding strength is improved. And meanwhile, by utilizing the thermal expansion characteristic of silicon carbide between graphite and ceramic, the purposes of buffering thermal mismatch stress step by step on the atomic scale, blocking high-temperature diffusion of carbon elements and endowing the coating with lasting high bonding strength and thermal cycling stability are achieved.

The invention relates to the field of coatings, in particular to an antibacterial formaldehyde-removing art coating and a preparation method thereof.The antibacterial formaldehyde-removing art coating is prepared from, by weight, 35-55 parts of organic silicon modified acrylic emulsion, 10-20 parts of filler, 3-8 parts of antibacterial formaldehyde-removing composite material, 5-10 parts of pigment, 0.1-0.3 part of defoaming agent, 0.1-0.5 part of dispersing agent, 0.2-0.6 part of thickening agent and 10-20 parts of deionized water. According to the prepared coating, the self-crosslinking type organic silicon modified acrylic emulsion is used, a compact and durable paint film can be formed, and stable support is provided for functional components. The antibacterial formaldehyde-removing composite material and the porous filler are introduced, formaldehyde and bacteria are physically adsorbed and enriched through a porous frame of the antibacterial formaldehyde-removing composite material and the porous filler, then a loaded bimetallic complex is used as an efficient catalytic center, formaldehyde is degraded into harmless substances, and meanwhile, the antibacterial formaldehyde-removing composite material also has an efficient and lasting broad-spectrum antibacterial effect.

A kind of fabric of lasting cool feeling, its structure includes breathable surface layer;Skin-friendly bottom layer, be located in the bottom surface of the breathable surface layer;A plurality of active contact type cool feeling structures are equipped on the skin-friendly bottom layer, adopt double-layer fabric with active contact type cool feeling structure, by breathable surface layer, with the skin contact skin-friendly bottom layer cooperate active contact type cool feeling structure to skin and carry out lasting cool feeling contact, even in fabric wrinkle place can actively contact with skin cool feeling, specifically, when external airflow enters breathing type notch by breathable surface layer, airflow will act on breathing cool feeling diaphragm, since the bottom of connecting piece is limited, so that breathing cool feeling diaphragm drives connecting piece top to change, the top of elastic silk column will be stretched and changed, the bottom end of breathing cool feeling diaphragm will be exposed breathing type notch, actively contact with skin.

The present invention provides long-lasting fragrance compositions that impart to a consumer a long-lasting perception and / or intensity of a perfume during fragrance wear. The present invention provides long-lasting fragrance compositions for prolonging the performance of a fragrance oil.

The present invention provides an active energy ray-curable antifogging coating composition capable of forming a cured film having long-lasting antifogging properties and excellent abrasion resistance, bleed resistance, adhesion, and damp heat resistance. The present invention also provides such a cured product and a laminate. The present invention relates to an active energy ray-curable antifogging coating composition including a radically polymerizable compound (A) having a structure of any of formulas (1) to (3) below, and a water-soluble surfactant (B); to a cured product of the active energy ray-curable antifogging coating composition; and to a laminate having a film including the cured product

The invention belongs to the technical field of ceramics, and particularly relates to a preparation method of antibacterial ceramics and an antibacterial ceramic product. The method comprises the following steps: firstly, preparing a ceramic matrix with a compact structure through wet co-grinding, molding and sintering; performing chemical vapor deposition on the surface of the substrate to form a layer of silicon dioxide film; then, a KH550 silane coupling agent is used for surface activation; finally, in the nitrogen atmosphere, 4, 4 '-bipyridine reacts with epoxy chloropropane to form a quaternary ammonium pyridine antibacterial layer on the surface through grafting. The antibacterial functional group is firmly anchored on the surface of the ceramic in a full chemical bonding manner, so that the problems that a traditional physical coating is easy to fall off and is not durable are solved. The obtained antibacterial ceramic has efficient, broad-spectrum and lasting antibacterial performance, the antibacterial rate is still kept at 98.8% or above after friction, and the antibacterial ceramic is suitable for the fields of daily supplies, building decoration, sanitary ware and the like.

The Abstract of this product is to provide a safe hard long-lasting chew for dogs. There is no choking hazard as it is liquid that's dried. Any dog of any size or age can safely consume the product.

The invention relates to the technical field of printing ink curing coatings, and discloses a preparation method of an external wall stone-imitating thermal insulation coating. The coating is prepared from the following components in parts by mass: 30 to 50 parts of acrylic emulsion, 8 to 20 parts of glass powder, 5 to 15 parts of ceramic powder, 15 to 30 parts of natural stone powder, 10 to 25 parts of sand grains, 0.3 to 1.2 parts of thickening agent, 0.5 to 1.5 parts of wetting dispersant, 1.5 to 3.5 parts of coalescing agent, 1 to 5 parts of mildew-proof weather-proof agent and 50 to 80 parts of water. By adding the glass powder, the ceramic powder and other components, a microcosmic heat insulation layer is formed in the coating, heat conduction is effectively reduced, energy consumption of a building is reduced, and a good heat insulation effect is achieved. The mildew-proof and weather-proof agent is a brand new compound, and long-acting bacteriostasis is realized by destroying cell walls of mildew or interfering a metabolic enzyme system of the mildew. The mildew-proof coating has high stability in a humid environment, is not easy to decompose, and can provide lasting mildew-proof protection for buildings.

The invention discloses an anti-static and anti-abnormal-sound coating for a durable automobile sealing strip and a preparation method of the anti-static and anti-abnormal-sound coating in the field of functional coating materials. The coating is prepared from hydroxy acrylic resin, two special functional fillers, auxiliaries and a solvent. Wherein the vinyl functionalized polypyrrole-silver nanowire hybrid conductive fiber provides a lasting static dissipation path, and the epoxy siloxane grafted perfluoropolyether solid lubricating particles provide long-acting lubrication through chemical bonding so as to eliminate abnormal sound. When the coating is prepared, the resin and the adhesion promoter are dissolved in the mixed solvent to form a resin liquid, then the two functional fillers and the lubricating additive are added after being pre-dispersed, and finally the mixture and the cross-linking agent are mixed and cured. The coating is firmly attached to the surface of the sealing strip through chemical bonding and endows the sealing strip with stable and lasting anti-static, noise-reducing and wear-resisting performance, and the process is simple and convenient and suitable for large-scale production.

1. The name of the design product: toothpaste box (long-acting refreshing and deodorizing toothpaste). 2. The use of the design product: the design product is used for the outer package of toothpaste products. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view.

The invention discloses a solid beer-flavor effervescent tablet and a preparation method thereof. The solid beer-flavor effervescent tablet comprises an acid source, an alkali source, a beer-flavor matrix, a sweetening agent, a filling agent, a nutrition enhancer and a processing aid, wherein the acid source comprises anhydrous citric acid, and the alkali source comprises sodium bicarbonate; the beer flavor matrix comprises malt flour, a humulus lupulus extract and a flavor enhancer, and the flavor enhancer comprises flavor essence and concentrated guava juice; the nutrition enhancer comprises vitamin B, mineral salt and an amino acid composition. According to the invention, rich and pure beer flavor and rich, fine and lasting foam can be generated after the beer is disintegrated in water, and the beer has good portability and long shelf life, and has a nutrition supplementing function.

An anti-dandruff composition comprising: (A) piroctone olamine, (B) at least one substance selected from the group consisting of salicylic acid and its derivatives, and (C) decylene glycol. The composition can provide a long-lasting anti-dandruff efficacy, and improve scalp health, scalp sensory properties, and a hydrating and smoothing efficacy of scalp.

The invention provides a damp-heat aging resistant three-layer waterproof adhesive tape as well as a preparation method and application thereof, and belongs to the technical field of waterproof adhesive tapes. The waterproof screen cloth comprises a screen cloth layer and a waterproof layer which are bonded through a bonding adhesive, the waterproof layer is coated with the TPU hot melt adhesive layer; the laminating glue comprises the following components in parts by weight: 95-105 parts of PU glue, 4-6 parts of precipitated silica, 8-12 parts of an isocyanate curing agent and 60-70 parts of butanone; the TPU hot melt adhesive layer is prepared from the following components in parts by weight: 45 to 60 parts of polyester polyol, 10 to 20 parts of polyether polyol, 20 to 25 parts of diphenylmethane diisocyanate (MDI), 5 to 10 parts of chain extender and the like. The adhesive tape solves the problems that the existing adhesive tape is poor in damp-heat aging resistance and the adhesive strength is easy to decrease by improving the formula of the laminating adhesive of the mesh cloth layer and the waterproof layer and the formula of the TPU hot melt adhesive layer, and has excellent damp-heat aging resistance, stable waterproofness and lasting adhesive strength.

This utility model relates to the field of conference equipment technology, specifically an array-type pickup module for conference microphones. It includes a pickup disc for the microphone, with an array microphone embedded in the center of the top surface of the pickup disc, and a fixed base on the bottom surface of the pickup disc. This utility model achieves efficient sound pickup for conferences through the pickup disc and the array microphone embedded in the center of its top surface. The pickup disc and the fixed base are integrally molded, enhancing the overall structural stability. The impact-resistant outer shell and anti-corrosion coating on the outer wall of the pickup disc effectively protect the internal components from external impacts and corrosion. A large-capacity battery embedded in the center of the bottom surface of the fixed base provides long-lasting power support for the array microphone. A power switch and several sets of touch buttons are located on the top edge of the fixed base for convenient operation and control. Several grooves on the outer wall of the fixed base facilitate lifting and moving the device.

The present application relates to a kind of self-cleaning coating for waterproofing membrane, waterproofing membrane and its preparation method, self-cleaning coating includes water-based acrylate emulsion and water-based fluorocarbon resin emulsion;Water-based fluorocarbon resin emulsion is by first polymeric monomer in the presence of solvent and the action of initiator first solution polymerization, obtain prepolymer, then join unsaturated isocyanate monomer and obtain photo-crosslinkable prepolymer, then join photo-initiator mixture, remove solvent, emulsification preparation is obtained by adding water.The self-cleaning coating prepared by redesigning fluorocarbon resin emulsion and using water-based acrylate emulsion can be used on waterproofing membrane, realize long-lasting stain resistance, while it can greatly slow down the aging of the membrane caused by environmental factors during outdoor use, improve the long-term durability of the membrane.

To provide a fabric and clothing made from it that quickly absorbs moisture, dries quickly, does not cause stickiness or discomfort from sweating, has a soft feel like natural fibers, and has a long-lasting cooling effect. [Solution] The material comprises a surface layer (2), a back layer (3), and an intermediate layer (4). The surface layer (2) is composed of surface yarns (20) containing hydrophilic fiber yarns, the intermediate layer (4) is composed of connecting yarns (40) made of water-absorbing fiber yarns, and the back layer (3) is composed of back yarns (30) made of fiber yarns in which water-absorbing fiber yarns are coated with water-non-water-absorbing fibers. The intermediate layer (4) is positioned between the surface layer (2) and the back layer (3), and the connecting yarns (40) constituting the intermediate layer (4) connect the surface yarns (20) constituting the surface layer (2) and the back yarns (30) constituting the back layer (3), forming an integral structure.

The invention relates to a method for producing a motor flange (1) for an electric motor (2), in which - a bearing bush (3) made of steel is provided, - the bearing bush (3) is inserted into a casting mould for the motor flange (1), - the motor flange (1) is cast from aluminium, - the motor flange (1) is finished-machined together with the cast-in bearing bush (3). As a result, a cost-effective and at the same time long-lasting integration of the bearing bush (3) in the motor flange (1) can be ensured.

An eyelash molding device includes an applicator interface including a concave molding surface, a plurality of ribs extending across the concave molding surface, a plurality of vents, wherein a vent is placed between two adjacent ribs, an air propulsion unit that delivers air to the vents, and a heating element that heats the air prior to exiting through the vents.

The application belongs to the field of oral products, and specifically discloses an oral product and a preparation method and application thereof. The oral product comprises the following components in percentage by mass: a curing agent 0.1-20%, a filler 5-80%, traditional Chinese medicine powder 0.2-60%, and plant essential oil 0.5-20%. The curing agent contains at least one functional group selected from a carboxyl group, an ester group and a hydroxyl group. The oral product in the application uses traditional Chinese medicine powder as a main component for refreshing the mind, and the plant essential oil is solidified by a curing agent and then mixed with the filler and the traditional Chinese medicine powder to prepare a natural, green, healthy and pleasant-smelling oral product for refreshing the mind. The oral product in the application not only solves the problem of unacceptable smell of traditional Chinese medicine, but also solves the problems of easy evaporation, yellowing and discoloration of natural plant essential oil through solidification of the plant essential oil. The prepared oral product still has a strong fragrance and a long-lasting refreshing effect after long-term storage.

The invention relates to the use of an animal-protein-free botulinum toxin composition to treat a disease, disorder or condition in a patient in need thereof whereby the animal-protein-free botulinum toxin composition exhibits a longer lasting effect in the patient compared to an animal-protein-containing botulinum toxin composition.

The present application relates to the technical field of freeze-dried powder, and in particular to a freeze-dried powder composition for hair regeneration and a preparation method thereof. The freeze-dried powder composition comprises 5-15 parts of vascular endothelial growth factor, 3-10 parts of platelet-derived growth factor, 1-5 parts of copper peptide, 0.5-3 parts of acetyl tetrapeptide-3, 2-8 parts of baicalein, 1-5 parts of asiaticoside, 20-40 parts of freeze-drying protectant, and 1-3 parts of nano-silicon dioxide. The preparation method comprises mixing the pretreated vascular endothelial growth factor, platelet-derived growth factor, copper peptide, acetyl tetrapeptide-3, baicalein, and asiaticoside with the freeze-drying protectant and nano-silicon dioxide, and then freeze-drying. The freeze-dried powder composition can promote the growth of hair, improve the microenvironment of the scalp, and provide long-lasting support for the healthy growth of hair. The preparation method improves the stability and biological activity of the active ingredients, and enhances the overall performance and safety of the product.

The invention relates to the field of daily cosmetics, and mainly relates to a high-stability thickening system and application. The high-stability thickening system is prepared from the following components in parts by mass: 0.001 to 5.0 parts of cetostearyl alcohol, 0.001 to 3.0 parts of cocamide MEA, 0.001 to 3.5 parts of cocamide DEA and 0.1 to 3.0 parts of di (hydrogenated tallow) phthalic acid amide. The invention provides a thickening system with high stability and excellent skin feeling, and when the thickening system is applied to a personal care product, a lasting pearl effect can be brought, and the thickening system adapts to a wider formula environment.

The present application relates to the technical field of ink curing coating, and discloses a preparation method of external wall stone-like thermal insulation coating, which is composed of the following components in mass fraction: 30-50 parts of acrylic emulsion, 8-20 parts of glass powder, 5-15 parts of ceramic powder, 15-30 parts of natural stone powder, 10-25 parts of sand, 0.3-1.2 parts of thickening agent, 0.5-1.5 parts of wetting dispersant, 1.5-3.5 parts of film-forming aid, 1-5 parts of mildew-resistant weathering agent and 50-80 parts of water. The external wall stone-like thermal insulation coating of the present application forms a micro heat insulation layer in the coating by adding components such as glass powder and ceramic powder, effectively reduces heat conduction, reduces the energy consumption of buildings, and achieves good thermal insulation effect. The mildew-resistant weathering agent used is a new compound, which can achieve long-term bacteriostasis by destroying the cell wall of mold or interfering with its metabolic enzyme system. It has high stability and is not easy to decompose in a humid environment, and can provide long-lasting mildew protection for buildings.

The present invention relates to denture adhesive compositions. The compositions comprise (a) carboxymethylcellulose, (b) a cross-linked polyacrylic acid homopolymer and (c) an alkyl vinyl ether-maleic acid copolymer or salt thereof. Advantageously, the compositions provide an immediate, strong and long-lasting hold.

The application discloses a protective base film for a polarizing plate and a preparation method thereof, and belongs to the technical field of optical display device protective films; the protective base film comprises an antistatic PET base material layer and a self-adhesive layer; the antistatic PET base material layer is made of optical-grade PET chips and antistatic master batches; the master batches are prepared by taking ionic liquid dihydric alcohol as a comonomer, and the master batches endow the base film with long-lasting and stable intrinsic antistatic properties; the self-adhesive layer is formed by melt blending polyurethane acrylate prepolymer, modified montmorillonite fillers and other matrix materials and auxiliaries in a specific ratio, and through an online UV curing process. Through innovative material design and integrated forming process, the prepared protective base film has excellent optical transparency, long-lasting antistatic property, suitable adhesive strength, clean peelability and excellent moisture and heat aging resistance, and the comprehensive performance is significantly better than that of a traditional glue-coated protective film, and the production process is more environmentally friendly and efficient.