The present invention provides
a peptide for promoting the regeneration of
hard tissue and / or dental pulp tissue and for treating
dentin-pulp
disease and / or
periodontal disease, as well as a pharmaceutical composition, a quasi-
drug composition, and a
functional health food composition containing the
peptide. [Solution] In one embodiment, the present invention provides
a peptide comprising an
amino acid sequence of the general formula KY-R1-R2-R3-R4-R5 (R1 and R2 are
arginine,
lysine,
glutamine, or
asparagine, respectively, and R3, R4, and R5 are
arginine or
lysine, respectively), which has been modified by
acetylation, amidation, or
methylation at the N-terminus or C-terminus, introduction of a D-
amino acid, modification of
a peptide bond of CH2-NH, CH2-S, CH2-S=O, or CH2-CH2, backbone modification, and
side chain modification; and a pharmaceutical composition, a quasi-
drug composition, and a
functional health food composition each containing the
peptide.