The invention provides multifunctional pure natural mouthwash and a preparation method thereof. The mouthwash contains sweetening agent, acidity agent, wetting agent, essence, alcohol, 0.5-1% of active constituent stabilizing agent, 0.01-0.3% of active constituent modifier and 0.05-0.1% of the active constituent deionized water, wherein the active constituents are at least two of tea polyphenol, propolis and Magnolia officinalis. The preparation method comprises the following steps of: dissolving the sweetening agent and the acidity agent into water, and adding with the wetting agent to form water-soluble cleaning liquid; and dissolving the active constituents into the alcohol, adding with the active constituent stabilizing agent, the essence and the active constituent modifier, and stirring to form oily solution; slowly adding the oily solution into the cleaning liquid, evenly mixing, statically putting for a night, filtering, and aseptically processing to obtain final products. Because of the combined action of the active constituents, the multifunctional pure natural mouthwash has an effect for multiply preventing and curing oral problems, such as decayed tooth, and has the functions of diminish inflammation and sterilization, desensitization, hemostasis, breath freshening, etc.