23 results about "Neotame" patented technology

The invention provides electronic atomized liquid and a preparation method thereof.The electronic atomized liquid comprises organic acid neotame salt, the organic acid neotame salt is dissolved in the electronic atomized liquid to release neotame, and the mass fraction of the neotame in the electronic atomized liquid is larger than 0% and smaller than or equal to 0.2% based on the total mass of the electronic atomized liquid; the electronic atomized liquid comprises at least one of fatty aldehyde acetal and a pH regulator, the mass fraction of the fatty aldehyde acetal is 0%-1% based on the total mass of the electronic atomized liquid, and the pH regulator is used for regulating the pH of the electronic atomized liquid to be 2.5-6.0. According to the embodiment of the invention, the neotame is released by using the organic acid neotame salt, the fatty aldehyde acetal is used for replacing the corresponding fatty aldehyde substance, the pH value of the electronic atomized liquid is adjusted to be acidic, and the three stabilizers are combined or combined in pairs for synergism, so that the stability of the neotame in the electronic atomized liquid is effectively improved.

Disclosed herein are formulations (including sweet proteins and rare sugars) for improving the sweetness of low glycemic index rare sugars without altering the texture and flavor of the rare sugars and methods for improving the sweetness of rare sugars. More specifically, the present invention discloses methods for improving the sweetness of rare sugars without altering the sweetness profile, texture and flavor of the primary sugars. The invention also discloses the addition of Brazitame protein with liquid rare sugars at different temperatures during the synthesis of the rare sugars, before crystallization or before or after caramelization of the rare sugars, to increase sweetness. The Brazilian sweet protein increases the sweetness of rare sugars, but is not limited to D-psicose, D-tagatose, D-allose, isomaltulose, trehalose, sorbose, pinose, leucobiose and the like. The invention also provides for the evaluation of non-nutritional sweeteners (such as aspartame, acesulfame, sodium cyclamate, neotame, saccharin, sucralose, stevioside, etc.), as each has a limitation of taste quality if used with rare sugars. However, the use of Brazilian sweet protein does not alter the flavor and texture of rare sugars, and the taste profile matches sucrose.

The invention belongs to the technical field of ecological water, mainly relates to ecological water for removing fruit peculiar smell, and particularly relates to ecological water for removing fruit peculiar smell and a preparation method thereof. Neotame and glucose modified cortex phellodendri are matched with tupistra chinensis, pogostemon cablin, liquorice and clove to be decocted into a traditional Chinese medicine decoction. According to the invention, lactobacillus plantarum ATCC 8014 and bacillus subtilis ATCC 6633 are used for fermentation. The antibacterial activity of the ecological water is improved, and the bitter taste of the cortex phellodendri is effectively removed due to the synergism of the two sweetening agents, namely the neotame and the glucose. The bacillus subtilis HZ-72 antagonistic bacteria used in the invention can enhance the capability of inhibiting pathogenic bacteria. Syzygium aromaticum has antibacterial activity, pogostemon cablin has an antiviral effect, and the syzygium aromaticum and the pogostemon cablin cooperate to enhance the antibacterial The ecological water prepared by the invention can remove peculiar smell and preserve freshness, and has a great development prospect in the field of fruit preservation.

The present application relates to a kind of urea[ 13 C] reagent, by weight parts, urea[ 13 C] reagent includes urea[ 13 C] 10-75 parts;Citric acid 800-2500 parts;Mannitol 500-3000 parts;And flavoring agent 20-50 parts;Flavoring agent includes at least one of stevioside, sucralose, neotame and thaumatin.The present application reduces the amount of mannitol, without the need for a large amount of mannitol, to meet the quality requirements of product, reduce the risk of patients using drug, product appearance and content are stable and no impurities in normal temperature storage environment, product can be continuously maintained for 6 months in high temperature and high humidity environment.

The invention provides a Chinese pulsatilla root oral liquid preparation and a preparation method thereof.The Chinese pulsatilla root oral liquid preparation per liter comprises 300 g of Chinese pulsatilla roots, 150 g of rhizoma coptidis, 300 g of cortex fraxini, 225 g of cortex phellodendri, 50 ml of PEG-400, 20 g of xanthan gum, 20 g of hydrophilic colloidal silicon dioxide, 5 g of neotame, 1.5 g of ethylparaben and the balance auxiliary materials. The palatability is better, and the clinical effect is obviously improved compared with that of other similar products.

The utility model relates to the technical field of neotame processing, and discloses an automatic neotame feeding reaction kettle which comprises a reaction kettle body, a supporting frame and a feeding mechanism, the supporting frame is arranged on the other side of the reaction kettle body and connected with the feeding mechanism, a first motor is installed at the position, close to the upper end, of the middle of one side wall of the feeding mechanism, and a second motor is installed on the other side wall of the feeding mechanism. The output end of the first motor is connected with a transmission rod, the other end of the transmission rod is connected with a driving gear, the middle position of the lower side wall of the driving gear is meshed with a driven gear, and the driven gear is rotationally connected with a stirring assembly. According to the utility model, the driven gear acts on the stirring assembly for synchronous rotation, so that the problem that the neotame raw materials are moist due to environmental influence when the equipment is not used and are bonded together to influence the quality of the raw materials is avoided, and the neotame raw materials adsorbed on the inner wall of the feeding mechanism are scraped by the scrapers mounted on the two side walls of the stirring assembly, so that the stirring efficiency is improved. The raw material utilization rate is improved.

A sweetener according to exemplary embodiments comprises: a core including one selected from erythritol, xylitol, sorbitol, maltitol, mannitol, inositol, lactitol, isomalt, and allulose; and a shell surrounding at least a portion of the core and including one selected from stevia, enzyme-treated stevia, steviol glycoside, mogroside, thaumatin, sucralose, aspartame, saccharin, acesulfame potassium, and neotame, wherein a content ratio of the shell to the core may be 0.002 to 0.05. The sweetener has a core-shell structure, wherein the core and the shell are each made into a single raw material without any separate additives (e.g. excipients), and thus is close to zero calories.

The invention discloses a method for simultaneously detecting neotame and glycyrrhizin in tipping paper, which comprises the following steps: (1) sample extraction: weighing the cut tipping paper, adding into an acetonitrile aqueous solution, and carrying out ultrasonic extraction for a period of time to obtain an extracting solution; (2) sample dilution: diluting the extracting solution with a mixed solution of dihydric phosphate, acetonitrile and water, and filtering to obtain a test sample; and (3) sample determination: detecting by adopting a high performance liquid chromatography to obtain the content of neotame and glycyrrhizin in the tipping paper. According to the method disclosed by the invention, the neotame and the glycyrrhizin in the tipping paper can be fully extracted at one time, the chromatographic peak is good, and the detection time is short.

The invention relates to the technical field of tobacco packaging materials, solves the problems that traditional cigarette tipping paper ink is easy to permeate when being in contact with bead blasting oil, so that printed patterns are fuzzy and paper is adhered, and discloses sweet cigarette tipping paper ink capable of preventing bead blasting oil permeation. Comprising the following raw materials in percentage by weight: 10-15% of cellulose acetate butyrate, 5-10% of cellulose nitrate, 1-5% of neotame, 1-5% of saccharin sodium salt, 0.5-1.0% of polytetrafluoroethylene wax, 0.5-1% of modified silicon dioxide and 60-70% of absolute ethyl alcohol, the cellulose acetate butyrate and the cellulose nitrate form a film-forming substrate, the neotame and the saccharin sodium salt serve as a compound sweetening agent, and the absolute ethyl alcohol serves as a solvent. And polytetrafluoroethylene wax and modified silicon dioxide are used as synergistic oil-proof penetrating agents. The anti-explosion bead oil has the advantages that the anti-explosion bead oil permeability of a printed matter under the condition that a sweetening agent is added is improved, the ink layer can prevent the anti-explosion bead oil from permeating after the anti-explosion bead arranged in the cigarette holder is broken, and the surface is kept smooth and not sticky.

The present disclosure addresses the problem of providing a technology for suppressing insolubilization due to storage of a coating film in an encapsulated formulation in which a content including a medium-chain fatty acid triglyceride is encapsulated in the coating film including gelatin.　This encapsulated formulation comprises a content including a medium-chain fatty acid triglyceride, neotame, and sucralose, wherein the content is encapsulated in a coating film including gelatin.

The invention provides a combined prebiotic preparation and application thereof, and belongs to the technical field of feed additives. The combined prebiotic preparation comprises the following components in percentage by weight: 87-95% of prebiotics, 1-3% of astragalus membranaceus, 1-3% of bighead atractylodes rhizome and 1-3% of liquorice. The prebiotics are one or a mixture of more of fructo-oligosaccharide, galactooligosaccharide and yeast cell wall polysaccharide according to an equal ratio, the flavoring agent is one or a mixture of more of banana essence, meat essence and citral according to an equal ratio, the sweetening agent is one or a mixture of more of saccharin sodium and neotame according to an equal ratio, and the sweetening agent is one or a mixture of more of citric acid sodium and neotame according to an equal ratio. The prepared combined prebiotic preparation is used for mixing feed and feeding livestock or poultry, has the effects of promoting growth and development, improving the gastrointestinal environment, enhancing disease prevention and control and the like, and achieves the purposes of promoting the growth of bred animals and improving the health level.

The invention relates to the technical field of compound synthesis, in particular to a neotame preparation method which comprises the following steps: adding 3, 3-dimethylbutyraldehyde, aspartame, acetic acid and a raney nickel catalyst into a methanol solvent to obtain a first mixed solution, introducing hydrogen into the first mixed solution to carry out hydrogenation reduction reaction, and after the hydrogenation reduction reaction is finished, separating and purifying to obtain neotame. The acetic acid is used for inhibiting the transesterification side reaction caused by the methanol solvent; performing reduced pressure distillation on the second mixed solution, adding an alkaline regulator to regulate the pH value of the second mixed solution, separating out a neotame crude product, and refining and purifying the neotame crude product to obtain neotame. Therefore, the crystallization efficiency and the product purity of the neotame crude product are improved.

The invention provides a neotame composition, an electronic atomization liquid and an electronic atomization system. The neotame composition comprises neotame, a neotame stabilizer and a first solvent in a mass ratio of 1: (0.01-2): (0.1-40), wherein the neotame stabilizer comprises a first stable component, and the first stable component comprises one or two of carotenoid and a rosemary extract. According to the neotame composition provided by the invention, the neotame and the neotame stabilizer are cooperatively used, and the carotenoid and the rosemary extract are rich in carnosic acid and rosmarinic acid, so that the neotame composition has relatively high oxidation resistance, and the stability of the neotame can be effectively improved.

The present application relates to the technical field of Parkinson's disease model construction of zebrafish, and specifically discloses a method for constructing a Parkinson's disease model of zebrafish induced by artificial sweetener neotame and application thereof, and the technical points are as follows: the method comprises the following steps: mixing neotame with water to obtain a neotame aqueous solution mother liquor with a mass concentration of 1 g / L; diluting the mother liquor into a working solution with a mass concentration of 1-100 mg / L by using breeding water; and breeding zebrafish in the working solution for 4 weeks to obtain a Parkinson's disease animal model of zebrafish induced by neotame. The present application also provides a model constructed by the method, an evaluation method of the model and application thereof. The model can be used for research on nervous system diseases, screening of neotame neurotoxicity, evaluation of neotame neurotoxicity in food and high-throughput screening of anti-Parkinson drugs.

The invention provides a method for acquiring a region of interest of a hyperspectral image of tipping paper for cigarettes, which comprises the following steps of: acquiring the hyperspectral image of the tipping paper for cigarettes and performing background removal processing to generate an initial region of interest; extracting spatial features and spectral features of the initial region of interest, performing clustering segmentation on the initial region of interest by using a spatial-spectral feature fusion method, and dividing the initial region of interest into a plurality of homogeneous sub-regions; and according to the average hyperspectral curve of each sub-region, identifying an abnormal region and cleaning the abnormal region, and reconstructing the cleaned sub-regions to form a final region of interest. The invention also provides a method for detecting the content of neotame in the tipping paper for cigarettes on the basis of the method for acquiring the region of interest of the hyperspectral image of the tipping paper for cigarettes. According to the method, a stable and reliable region of interest of a pure base material is output through triple technical guarantee of deep feature fusion, region clustering segmentation and intelligent post-processing, and reliable technical support is provided for high-precision and high-efficiency online quality detection of tipping paper for cigarettes.

The invention discloses a sample processing method for detecting neotame content in food, which is characterized by comprising the following steps: 1) preparing a sample to be tested; 2) extracting the sample: 2.1) adding the sample into a container, adding an extracting solution, and adjusting the pH value to 4-5; the addition amounts of the sample and the extracting solution satisfy the following ratio: 1 g: 5-10 mL; 2.2) heating the sample in a water bath at 50-70° C., adding n-hexane, centrifuging, and discarding the n-hexane layer; the addition amounts of the sample and n-hexane satisfy the following ratio: 1 g: 0.8-1.2 mL; 2.3) adding an 80-100 g / L potassium ferrocyanide aqueous solution and a 150-200 g / L zinc acetate aqueous solution, centrifuging, and transferring the supernatant; the addition amounts of the sample, potassium ferrocyanide aqueous solution, and zinc acetate aqueous solution satisfy the following ratio: 1 g: 0.1 mL-0.4 mL: 0.1 mL-0.4 mL. This sample pretreatment method is suitable for testing a variety of food matrices, covering the 14 major food categories specified in GB 2760-2014. It is highly versatile and improves detection accuracy and efficiency. The recovery rate of Niutian is 80% to 110%.

The invention relates to a composition which comprises the following components in parts by weight: 11.2-30.8 parts of a sweetening agent combination and 69.2-88.8 parts of a solvent for dissolving the sweetening agent combination, the sweetening agent combination consists of neotame, sucralose, glucosyl stevioside, erythritol and glycyrrhizic acid, and the sweetening agent combination consists of neotame, sucralose, glucosyl stevioside, erythritol and glycyrrhizic acid. Wherein the weight ratio of the neotame to the sucralose to the glucosyl stevioside to the erythritol to the glycyrrhizic acid is 1: (1-3): (1-3.5): (2.5-7.5): (0.1-0.4). According to the composition, the taste of the atomized liquid during smoking is improved, and meanwhile, the sweetening speed is increased. The invention also relates to a nebulized liquid, a nebulizer and a nebulizing device comprising the sweetener combination, and the use of the sweetener for preparing the nebulized liquid.

The invention discloses a sour and sweet composition, atomized liquid and an electronic atomization device.The sour and sweet composition comprises a first sour component, a second sour component, a first sweet component and a second sweet component, the first sour component comprises at least one of acetic acid and propionic acid, and the second sour component comprises at least one of lactic acid, citric acid and malic acid; the first sweet component comprises at least one of neotame and sucralose, and the second sweet component comprises at least one of perilla lepidium and damascenone B; wherein the sour and sweet composition is prepared from the following components in parts by mass: 12 to 18 parts of a first sour component, 4.5 to 10 parts of a second sour component, 1.5 to 2 parts of a first sweet component and 0.13 to 0.6 part of a second sweet component. The sour and sweet composition provided by the invention can enrich the sour taste and increase the sweet feeling and the juice feeling of the oral cavity at the same time, so that the user experience can be improved.

The invention discloses a liquid chromatography method for simultaneously detecting three sweeteners in tipping paper, which comprises the following steps: (1) sample extraction: weighing the cut tipping paper, adding into an acetic acid-ammonium acetate-acetonitrile aqueous solution, and carrying out ultrasonic extraction for a period of time to obtain an extracting solution; and (2) sample determination: detecting by adopting a high performance liquid chromatography to respectively obtain the contents of neotame, sucralose and glycyrrhizin in the tipping paper. According to the method disclosed by the invention, the neotame, the sucralose and the glycyrrhizin in the tipping paper can be fully extracted at one time, and the detection time is short.

The invention relates to the technical field of conveying, in particular to a detecting and sampling device and process in neotame production, comprising a middle plate, the lower surface of the middle plate is connected with a bottom plate through a lifting mechanism, a charging barrel is fixedly mounted in the middle of the upper surface of the middle plate, and a liquid outlet is fixedly embedded in the front end of the lower surface of the charging barrel; a connecting sleeve is fixedly arranged at the front edge of the upper surface of the middle plate, a rotating seat is rotationally embedded in the inner side of the connecting sleeve, a discharge pipe fixedly penetrates through the middle of the rotating seat, an upper end opening of the discharge pipe is communicated with a lower end opening of the liquid discharge opening through a hose, and a notch is formed in the lower rear surface of the rotating seat; according to the invention, cuvettes can be conveniently and quickly arranged and sampled, so that an operation table top is tidier, and the use of scattered tools is reduced; the problems of liquid dropping and liquid leakage at the port can be prevented, and the environment is clean and tidy; the device has good adaptability, can be used for guiding and sampling according to the shape of a cuvette, and brings convenience.

The application provides a neotame composition, an electronic atomizing liquid and an electronic atomizing system. The neotame composition comprises neotame, a neotame stabilizer and a first solvent in a mass ratio of 1:(0.01-2):(0.1-40); wherein the neotame stabilizer comprises a first stabilizing component, and the first stabilizing component comprises one or both of carotenoids and rosemary extract. The neotame composition provided by the application can effectively improve the stability of neotame by using the combination of neotame and the neotame stabilizer, and the carotenoids and rosemary extract contain rich carnosic acid and rosmarinic acid, and have strong antioxidant properties.

The invention belongs to the field of food additives, and particularly relates to a compound mogroside sweetening agent and a preparation method thereof. Various sweetening agents such as mogroside, siraitia grosvenorii powder, sucralose and neotame are compounded, and the optimal proportion range is obtained through multiple tests, so that the defect of single mogroside is overcome, the sweetness can be further increased, the bad taste can be reduced, and the stability of the product can be improved and stabilized.

The present application relates to a kind of for detecting helicobacter pylori and its preparation method, by weight parts, its raw material includes: urea [ 13 C]10~75 portions, sodium bicarbonate 5~110 portions, lactose 15~45 portions, citric acid 1000~2500 portions, flavoring agent 50~150 portions.The flavoring agent includes at least one of stevioside, sucralose, aspartame, neotame, thaumatin, acesulfame potassium.The present application adopts the way of citric acid and tablet storage separately, effectively solves the problem of flavoring agent addition, avoids the problem of impurity generation due to citric acid addition;At the same time, mannitol is not used in medicine, reduces the risk of patient using medicine.