2096 results about "Formic acid" patented technology

The invention provides triazole anthracene methyl formate for a photosensitive resin composition, and relates to the field of photopolymerization. The invention also comprises a photosensitive resin composition containing the triazole anthracene methyl formate, a photosensitive dry film containing the triazole anthracene methyl formate, and applications of the photosensitive resin composition and the photosensitive dry film. The triazole formic acid anthracene methyl ester disclosed by the invention has photosensitivity, can be used as a photosensitizer in the photosensitive resin composition, can improve the adhesive force of the photosensitive resin composition on various metal surfaces, and has the characteristic of low migration; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The invention relates to the field of organic chemical synthesis, in particular to a synthetic method and application of pyrimidone compounds. The invention provides a synthesis method, reactants are o-amino heterocyclic formamide and triethyl orthoformate respectively, a solvent system is a hexafluoroisopropanol solvent, and a product is a heterocyclic pyrimidone compound. The reaction does not need strong acid or strong alkali conditions, does not need additional reducing agents or oxidizing agents, does not need transition metal catalysis, is economical and practical, the reaction conditions are relatively mild, and the synthesized pyrimidone compound has a good antibacterial effect.

The invention belongs to the technical field of nanocrystal nucleus early strength agents, and provides a damp and hot nanocrystal nucleus early strength agent, a tailing solidification filling material and a preparation method and application of the damp and hot nanocrystal nucleus early strength agent and the tailing solidification filling material. The invention discloses a molybdenum ore tailing slurry which is prepared from the following raw materials in parts by weight: 1 part of Portland cement, 4 to 6 parts of molybdenum ore tailings, 0.06 to 0.1 part of zeolite powder, 0.07 to 0.1 part of nanoscale attapulgite powder, 0.06 to 0.1 part of gamma-glycidyl ether oxypropyl trimethoxy silane, 0.03 to 0.1 part of potassium silicate, 0.04 to 0.1 part of sodium hydroxide, 0.06 to 0.1 part of calcium formate, 0.04 to 0.1 part of lithium metaaluminate and 1.25 to 1.75 parts of water. According to the technical scheme, the problem that a filling body prepared from an early strength agent in the prior art is low in early and later strength is solved, and meanwhile, the early strength agent is simple and convenient in preparation mode, low in cost and wide in application range.

The application discloses a thickened oil viscosity reducer for a main viscosity contribution component of colloid and a preparation method thereof. The thickened oil viscosity reducer comprises the following components in percentage by weight: diethylene glycol methyl ether 25-35%, propylene glycol formate 15-25%, dispersant 5-8%, chelating agent 2-4%, anti-coking agent 0.5-1%, anti-swelling agent 1-2% and corrosion inhibitor 1-2%; and the balance is water. The application is a polar + non-aromatic hydrocarbon solvent system; completely avoids high-risk substances such as nonylphenol polyoxyethylene ether, petroleum sulfonate sodium and organic chlorine; is designed in pertinence and can effectively inhibit metal-induced asphaltene bridging; can withstand working conditions from normal temperature to 250 DEG C and up to 300 DEG C; thermal stability is significantly enhanced, and residual carbon after aging is lower than 8%; viscosity reduction efficiency is higher; the system is more stable, flexible in compounding and suitable for field construction.

The invention provides chlorotrifluoroethylene continuously prepared based on a microchannel reactor and a preparation method of the chlorotrifluoroethylene, and the chlorotrifluoroethylene comprises the following raw materials in parts by weight: 1, 1, 2-trifluoro-1, 2, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3, 3 The low-temperature refrigerant refrigerant is prepared from the following components in parts by weight: 90 to 100 parts of 1, 2-trichloroethane, 1 to 5 parts of a zinc fluoride induced palladium-copper bimetallic catalyst, 8 to 15 parts of a cyclohexyl dimethyl ether-formic acid composite hydrogen donor, 0.5 to 2 parts of trifluoroacetic anhydride, 0.1 to 0.5 part of a perfluoropolyether lubricant, a proper amount of a low-temperature mixed refrigerant and 15 to 20 percent by weight of diluted hydrochloric acid. According to the invention, the preparation efficiency and product purity of chlorotrifluoroethylene can be improved, and stable operation of the preparation system and reasonable treatment of byproducts can be guaranteed.

The invention provides a construction method and application of a fingerprint spectrum of a liver-warming decoction, and belongs to the technical field of medicine detection.The construction method includes the steps that a test solution is prepared through the liver-warming decoction, acetonitrile (A)-0.08-0.12 wt% formic acid aqueous solution (B) serves as a mobile phase, and the fingerprint spectrum of the liver-warming decoction is obtained through high performance liquid chromatography detection; and a standard fingerprint spectrum is established and is used for quality evaluation or control in the whole process of research / development / production / clinical application of the liver-warming decoction. According to the construction method of the fingerprint spectrum of the liver-warming decoction, main medicinal material components in the liver-warming decoction can be detected through high performance liquid chromatography, so that the quality condition of the liver-warming decoction can be reflected more comprehensively.

A method for preparing 1,2-propanediol involves reacting propene with hydrogen peroxide in the presence of a catalyst mixture containing a phase transfer catalyst and a heteropolytungstate, in a liquid reaction mixture containing an aqueous phase with a maximum apparent pH of 6 and an organic phase. The process then involves separating the reaction mixture into an aqueous phase (Pa) containing 1,2-propanediol and an organic phase (Po); recycling at least part of the separated organic phase (Po) to the reaction; and recovering 1,2 propanediol from the separated aqueous phase (Pa). In the recovery, 1,2-propanediol is separated from the aqueous phase (Pa) by distillation and the apparent pH of the separated aqueous phase (Pa) is adjusted to at least 9 prior to the distillation to reduce the content of formic acid and acetic acid in the recovered 1,2-propanediol.

Escherichia coli is modified by means of metabolic engineering, a genetically engineered bacterium for high yield of O-succinyl-L-homoserine is obtained, and a construction method of the genetically engineered bacterium comprises the following steps: weakening a synthetic route of an organic acid metabolic byproduct of a chassis strain E.coli W3110 [delta] metI [delta] metJ [delta] thrB [delta] metB; wherein the synthetic route of the organic acid metabolic byproducts is selected from at least one of a formic acid synthetic route, a lactic acid synthetic route and an ethanol synthetic route. The constructed genetically engineered bacterium is applied to microbial fermentation production of the O-succinyl-L-homoserine, effective accumulation of the O-succinyl-L-homoserine is achieved, the sugar acid conversion rate reaches 46.8%, and a foundation is laid for subsequent construction of high-yield O-succinyl-L-homoserine engineering bacteria.

The invention belongs to the field of PET (polyethylene glycol terephthalate) plastic waste treatment, and particularly relates to preparation of a copper oxide-nickel hydroxide core-shell structure catalytic material and application of the copper oxide-nickel hydroxide core-shell structure catalytic material to preparation of high-added-value formic acid by upgrading electro-catalysis PET plastics, and the preparation method comprises the following steps: (1) placing a copper conductive substrate in an alkali etching mixed solution for alkali etching treatment, obtaining a conductive substrate on which a Cu (OH) 2 precursor grows; (2) placing the conductive substrate on which the Cu (OH) 2 precursor grows in a muffle furnace for heat treatment to obtain a conductive substrate on which CuO nanowires grow; and (3) placing the conductive substrate on which the CuO nanowire grows in a hydrothermal kettle, and obtaining the CuO-coated Ni (OH) 2-x core-shell structure catalyst through a hydrothermal method.

The invention belongs to the technical field of material chemistry, and particularly relates to a method for synthesizing an amide hydrogen bond organic framework material based on a one-pot method and gold recovery application. The preparation method comprises the following steps: dissolving a dihydroxybenzidine monomer in a formic acid monomer under 15-minute ultrasonic treatment, then adding ethylene glycol, and then carrying out ultrasonic treatment on the mixture for 5 minutes; then placing the sample bottle in a drying oven at 30 DEG C for constant-temperature evaporation so as to separate out brown blocky crystals; and filtering and collecting crystals, washing with water for multiple times, and carrying out vacuum drying at 60 DEG C to obtain the final material HOF-D. The HOF-D synthesized by the method disclosed by the invention can be used for rapidly recovering Au (III) from an aqueous solution with high selectivity, cycling stability and large capacity (5186 + / -10 mg. G <-1 >), so that the efficient adsorption and recovery of Au (III) in electronic waste liquid are realized, and the HOF-D has a good application prospect.

The invention discloses a dual-band acridine formic acid anthracene methyl ester photocatalyst as well as a preparation method and application thereof, and belongs to the field of heterocyclic compounds. The invention designs and synthesizes a novel acridine formic acid anthracene methyl ester photocatalyst, which has good compatibility in two wavebands of 365 nm and 405 nm, can realize photocatalysis of disulfide compounds and aryl formyl peroxide compounds, and provides a new thought for preparation of sulfoxide compounds with asymmetric structures; the reaction conditions are mild, the reaction time is short, the photocatalyst can be recycled, the circulation loss is low, the circulation efficiency is high, the production efficiency is greatly improved, and the production period and cost are reduced; the product is free of transition metal residues and high in yield.

The invention discloses a preparation process of berberine hydrochloride, and belongs to the technical field of berberine production. The invention relates to a berberine hydrochloride preparation process, which comprises: S1, mixing a ferric sulfate-aluminum sulfate composite salt, sodium chloride, zinc chloride and anhydrous formic acid, pre-activating, adding N-2, 3-dimethoxybenzyl homopiperony lamine hydrochloride, dropwise adding a glyoxal mixed solution, and carrying out a reflux reaction. And S2, cooling the reaction liquid until a solid is separated out, filtering, adding a filter cake and diatomite into purified water, stirring, adjusting alkali, heating, and continuously stirring for 0.5-1 hour. Cooling and filtering, and reserving filtrate; s3, adjusting the acidity of the filtrate, cooling and growing crystals; and filtering, rinsing a filter cake, and carrying out vacuum drying on the filter cake to obtain berberine hydrochloride. The berberine hydrochloride prepared by the method is high in yield and purity, and the preparation process is safe, short in flow and friendly to human bodies and environment.

This invention belongs to the field of chemical synthesis and relates to a method for achieving deuterated methylation of a nucleophile. The invention provides a deuterated methylating reagent, which is obtained by reacting formic acid with deuterated methanol under acidic conditions, followed by a second reaction with thiaanthracite and trifluoromethanesulfonic acid. The nucleophile is then reacted with the deuterated methylating reagent described in claim 1, a base, and a solvent to obtain the deuterated methylated product. This invention also provides a method for achieving deuterated methylation of a nucleophile, which involves dissolving the nucleophile and 5-deuterated methyl-5H-thiophene-5-onium trifluoromethanesulfonate in a suitable solvent, adding a base, and then performing the deuterated methylation reaction at room temperature. In the method provided by this invention, the yield of the product after nucleophile methylation can reach 52% to 95%.

The application provides a surface fluorine-modified bismuth vanadate photoelectrode and a preparation method and application thereof. Fluorine atoms are attached to the surface of the bismuth vanadate, and part of the fluorine atoms replace the two-coordinated oxygen atoms on the surface of the bismuth vanadate, namely the surface fluorine-modified bismuth vanadate photoelectrode. The surface fluorine-modified bismuth vanadate photoelectrode greatly improves the oxidation rate and molecular reaction efficiency of hydroxyl radicals generated by photoelectrolysis of water, effectively improves the glycerol oxidation efficiency, the selectivity of the product formic acid, and reduces the energy consumption of the reaction.

The invention relates to the technical field of preparation of catalytic materials, in particular to a preparation method of a manganese dioxide room-temperature catalyst, which comprises the following steps: dissolving a manganese-containing soluble salt in deionized water to form a solution A; adding an oxidizing agent F into the solution A to form a mixed solution B; s3, carrying out hydrothermal reaction on the mixed solution B to obtain a reaction product; washing the reaction product for multiple times, centrifuging, precipitating and drying to obtain a sample; and calcining the sample to obtain the manganese dioxide catalyst. According to the preparation method of the manganese dioxide room-temperature catalyst, the manganese dioxide phase structure is accurately regulated and controlled, and the manganese dioxide synthesized by the method for regulating and controlling the phase structure has high specific surface area and rich oxygen vacancies; meanwhile, accumulation of intermediate products such as formic acid and CO is effectively inhibited through high-density distribution of defect sites, and the formaldehyde removal rate at the room temperature (25 DEG C) can reach 90% or above.

The invention discloses a Pickering IL emulsion microreactor constructed on the basis of temperature-sensitive double-enzyme Janus spheres and application of the Pickering IL emulsion microreactor to enhanced catalysis of conversion of CO2 into formic acid. A Janus emulsion template method is combined with a photocuring technology to synthesize a nano-scale dual-functional temperature-sensitive Janus sphere, one half of the nano-scale dual-functional temperature-sensitive Janus sphere is a hydrophilic hydrocarbon polymer, the other half of the nano-scale dual-functional temperature-sensitive Janus sphere is a hydrophobic fluorocarbon polymer, and rapid inversion of a Pickering emulsion can be realized by utilizing temperature sensitivity. The method comprises the following steps: preparing a Janus particle hydrophilic / hydrophobic hemisphere, selectively immobilizing formate dehydrogenase FDH and carbonic anhydrase CA on the Janus particle hydrophilic / hydrophobic hemisphere to obtain a temperature-sensitive FDH-Janus-CA composite sphere, introducing a fluorine-functionalized ionic liquid to regulate and control the internal microenvironment of a microreactor, and constructing a Pickering IL emulsion microreactor. The CO2 absorption capacity is increased by 47 times compared with that of a pure water system, the formic acid yield reaches 27.5 mM and is higher than the maximum value 22.8 mM of current enzyme electrocatalysis, the storage and catalysis stability is good, and an efficient and sustainable scheme is provided for CO2 recycling.

The present application belongs to the technical field of the synthesis of chiral boron compounds, and in particular relates to an MOF-Cu(II) / CMC composite material, and a preparation method therefor and the use thereof. The preparation method for an MOF-Cu(II) / CMC composite material of the present application comprises: dropwise adding an aqueous solution of sodium carboxymethyl cellulose to an aqueous solution of a bivalent copper salt, performing solid-liquid separation, mixing obtained composite microspheres with an organic solution of trimesic acid, heating the resulting mixture, and subjecting same to solid-liquid separation, so as to obtain an MOF-Cu(II) / CMC composite material. The MOF-Cu(II) / CMC composite material is used in an asymmetric chiral boron addition reaction. The reaction is performed at room temperature, involves mild conditions, is applicable to a wide range of substrates and has a high yield and enantioselectivity. Moreover, the method can achieve the synthesis of a chiral organic boride in a solvent having simple components, providing an efficient new method for the preparation of drug molecules and active intermediates, and also broadening the range of substrates used for the preparation of chiral organic borides.

The invention provides a solid acid catalyst and application thereof in esterification reaction of polyethoxy dihydric alcohol and acrylic acid, and relates to the technical field of preparation of polyethylene glycol diacrylate. The solid acid catalyst is a UIO-66-SO3H catalyst based on a UIO-66 framework, the catalyst is prepared from ZrCl4, formic acid, terephthalic acid and 2-sulfonic acid terephthalic acid through a reaction, the catalyst can catalyze an esterification reaction of polyethyoxyl dihydric alcohol and acrylic acid under the solvent-free condition, a subsequent desolventizing step is avoided, energy consumption is reduced, and the method is suitable for industrial production. And the prepared polyethoxy glycol diacrylate product is colorless and transparent in color, high in purity, low in polymerization degree, moderate in viscosity and wider in application space.

The invention provides a Z-type heterojunction material for synchronously removing phosphorus and tetracycline in sewage. The material is composed of a hexagonal flaky nano magnesium-aluminum-iron hydrotalcite matrix with the size of 30-100 nm and a metal oxide growing on the surface. The preparation method of the material comprises the following steps: carrying out hydrothermal treatment on magnesium-aluminum-iron hydrotalcite and trimesic acid in N-N dimethylformamide liquid, growing a metal organic framework compound on the surface of the magnesium-aluminum-iron hydrotalcite in situ through dissolved-out metal ions and trimesic acid, and roasting the metal organic framework compound to obtain the Z-type heterojunction material. The Z-type heterojunction material can synchronously and efficiently remove phosphorus and tetracycline in sewage, the synchronous removal rates of 50 mg of the material to phosphorus and tetracycline are 97.60% and 95.47% respectively in 100 mL of a phosphorus (concentration of 25 mg / L) water sample and a tetracycline (concentration of 50 mg / L) water sample, and the synchronous removal rates of phosphorus and tetracycline are still 87.62% and 85.57% after continuous circulation for five times. The Z-type heterojunction material can be applied to the aspect of phosphorus and tetracycline mixed sewage treatment in the breeding industry.

The application provides a preparation method of finerenone and intermediates thereof. The application discloses a preparation method of a finerenone intermediate 5, which comprises the following steps: step 1: in an organic solvent, a resolution reaction is carried out between a finerenone intermediate 2 and D-tartaric acid diphenyl ester to obtain a resolution salt, then an acid-base reaction is carried out between the resolution salt and a base to obtain the finerenone intermediate 3; step 2: in an organic solvent, a nucleophilic substitution reaction is carried out between the finerenone intermediate 3 and triethyl orthoformate in the presence of an acid to obtain a finerenone intermediate 4; step 3: in a solvent, a hydrolysis reaction is carried out between the finerenone intermediate 4 to obtain the finerenone intermediate 5. The preparation method has the advantages of short reaction steps, high total reaction yield, simple and safe operation, simple post-treatment steps, high product purity, low production cost and suitability for industrial production.

The invention discloses a construction method and application of a protein fingerprint spectrum of Tilletia foetida teliospore. The method comprises the following steps: firstly, preparing immunomagnetic beads by using a monoclonal antibody for resisting Tilletia foetida teliospore, wherein the immunomagnetic beads are used for specifically enriching target teliospore in a wheat sample; then, the captured magnetic bead-teliospore compound is placed in a formic acid-acetonitrile solution and subjected to efficient cracking through steel ball grinding, and internal protein of the teliospore is released. The released protein is subjected to MALDI-TOF-MS analysis, so that a protein fingerprint spectrum of the protein is obtained, and a characteristic protein fingerprint spectrum database of the fungal spores is constructed. The rapid identification of the Tilletia foetida teliospore is realized by comparing and analyzing the mass spectrum of the sample to be detected and the self-established database. The detection time is shortened to be within 1 h, the sensitivity reaches up to 105 spores per gram of samples, and the method has the advantages of being simple, convenient, accurate and efficient and is particularly suitable for on-site rapid screening in the field of food quality safety.

The present disclosure relates to a crystalline form of trans-4-[1-(3-Chloro-phenyl)-7-methoxy-2,4-dioxo-3,4-dihydro-2H-pyrimido[5,4-c]quinolin-3-yl]-cyclohexanecarboxylic acid hydrochloride, methods of preparation, and its use as a therapeutic agent to treat inflammatory diseases.

The invention discloses a thin-layer chromatography identification method for cinnamon and ginger in vitality-preserving granules, and belongs to the technical field of pharmaceutical analysis. Aiming at the problems of step-by-step detection, serious cinnamic acid tailing and dependence on toxic solvents in the existing method, the method comprises the following steps: dissolving vitality-preserving particles in water, carrying out ultrasonic treatment, extracting filtrate by using absolute ether, merging extract liquor, evaporating to dryness, and dissolving by adding ethyl acetate to obtain a test solution; preparing a cinnamon reference medicinal material solution and a cinnamic acid and 6-gingerol reference substance solution; a silica gel GF254 thin-layer plate is adopted, petroleum ether-normal hexane-ethyl formate-formic acid is used as a developing solvent for developing, and inspection is conducted under the ultraviolet light of 254 nm and the ultraviolet light of 365 nm respectively. Cinnamon and ginger can be synchronously identified, spots are clear and free of trailing, no toxic solvent exists, durability is high, cost is low, and an accurate and reliable basis can be provided for quality control of the vitality-preserving granules.

The invention discloses a citric acid coordination regulated amino-functionalized palladium-silver alloy catalyst as well as a preparation method and application thereof. Nitrogen-doped carbon is used as a carrier, and the palladium-silver alloy catalyst is constructed through coordination-confinement in-situ reduction of citric acid. According to the preparation method, citric acid is introduced, and synergistic interaction of sub-nano-scale dispersion and efficient interface mass transfer is achieved through dual synergistic regulation and control of the size and the interface; the coordination effect enables the palladium-silver alloy to achieve sub-nano-scale superfine dispersion; as a competitive hydrogen bond acceptor / donor, the polycarboxyl group can effectively break an interface hydrogen bond network and inhibit the formation of a tight gas film from the source. The mechanism ensures that the catalyst is always in full contact with a mixed aqueous solution containing formic acid and formate and hydrogen is quickly released during formic acid dehydrogenation hydrogen production reaction, so that the catalyst has excellent anti-poisoning cycling stability while keeping high intrinsic activity, and the technical problem that high activity and long-term stability are difficult to consider at the same time is solved.

The invention belongs to the technical field of chemical production, and particularly relates to a novel process for separating pentaerythritol by a membrane method and application of the novel process. The membrane separation comprises the steps of separating sodium formate by using an ion exchange membrane and separating pentaerythritol by using a low-pressure nanofiltration membrane device. The dealdehyding liquid is separated through different membranes, and formic acid, pentaerythritol, dipentaerythritol and other substances can be effectively separated. The process greatly shortens the process flow and saves the cost. According to the technical scheme, the quality and performance of the pentaerythritol product are remarkably improved, the added value of the product is increased, and a new technical scheme is provided for industrial production of pentaerythritol.

The invention discloses a preparation method and application of double-doped biochar, and belongs to the technical field of biochar preparation, and the preparation method comprises the following steps: cleaning, drying and crushing apple branches to obtain branch powder with uniform particles; uniformly blending the branch powder, urea and potassium formate with deionized water, drying, and carrying out calcination reaction at 600-800 DEG C; cooling to room temperature, sequentially washing with diluted hydrochloric acid and deionized water until the pH is constant, and drying to obtain N-doped biochar; and uniformly blending the N-doped biochar and ammonium fluoride by using deionized water, drying, and carrying out calcination reaction at 400-600 DEG C to obtain the double-doped biochar. Compared with single N doping, the preparation method of the N and F double-doped biochar provided by the invention can more efficiently regulate and control pore development of the biochar, the step-by-step preparation method can accurately regulate and control the introduction effect of doped elements, the specific surface area of the prepared N and F double-doped biochar is greatly increased, and the preparation method is suitable for large-scale industrial production. And a sufficient structure bearing foundation is provided for the high-efficiency adsorption performance of the material.

The application discloses an automatic control method for oxidation flocculation parameters in mancozeb wastewater treatment, and belongs to the technical field of industrial wastewater treatment and automatic control. In view of the problem that the existing process relies on manual experience and the oxidation and flocculation stages are improperly connected, the multifunctional modified material containing dithiocarbamate salt groups, quinone groups and pre-complexed manganese and zinc ions is prepared first; the material and hydrogen peroxide are synchronously added in the acid oxidation stage, and the control system monitors the redox potential change rate in real time; when the redox potential reaches the preset threshold value and the characteristic change point with the first derivative of zero or the change from positive to negative appears and is maintained for the preset maintenance time, the system is automatically adjusted to be alkaline, the modified material triggers the net capture and chelation crosslinking reaction, and finally solid-liquid separation is carried out; the polymer skeleton is protected from indiscriminate attack of free radicals, the problem of drug antagonism is overcome, and the stable and up-to-standard effluent quality is realized.

The application provides an In-MOF crystal material and a preparation method and application thereof, and the molecular formula of the In-MOF crystal material is [In(phen)(BDC) 1.5 ]·H2O, wherein phen is 1,10-phenanthroline, and BDC is terephthalic acid ligand; the crystal belongs to a monoclinic crystal system P2 1 / n with a space group, and the cell parameters are alpha=90°, beta=97.774(2)°, gamma=90°, a=12.3359(3)Å, b=14.1993(4)Å, c=15.4995(4)Å, the cell volume is 2689.96(12)Å 3 , and Z=4. The application synthesizes an In-MOF crystal material by using a simple room temperature solvent evaporation method, and the In-MOF crystal material can be used as a catalyst for electrocatalytic carbon dioxide reduction, and realizes efficient carbon dioxide reduction to form formic acid.

The application provides a method for establishing a fingerprint spectrum of Wenshoujieyu granules and the fingerprint spectrum, and relates to the technical field of traditional Chinese medicine preparation detection. The method for establishing the fingerprint spectrum adopts high performance liquid chromatography to detect the Wenshoujieyu granules, and in the method, the chromatographic conditions are as follows: Agilent 5TC-C 18 (2) (4.6mm*250nm, 5um) is used as a chromatographic column; acetonitrile and 0.1% formic acid aqueous solution are used as mobile phases; the flow rate is 1mL*min ‑1 ; the column temperature is 45 DEG C; the injection amount is 15ul; and the detection wavelength is 300nm. The method for detecting the fingerprint spectrum of the Wenshoujieyu granules established by the application is simple in operation, reliable in result, high in stability and precision, and good in repeatability; the fingerprint spectrum provided by the application can be used to comprehensively and effectively control the quality of the preparation, and ensure the stability, reliability and safety of the preparation.

The application discloses a kind of ruthenium grafting manganese aluminum hydrotalcite and catalytic method for C02 hydrogenation preparation formic acid, belong to catalyst technical field, in the application, under the optimized reaction condition, with methanol:water mixture as solvent (5:1), total pressure is 60bar, 60 DEG C, reaction 24 hours, with temperature controller to be heated to the temperature required for reactor.When the temperature inside the reactor reaches the specified temperature, start stirring at a fixed stirring speed (200-800 revolutions / min), after the required reaction time, stop stirring and heating, and allow the reactor to cool to room temperature. The hydrogenation products were analyzed by high performance liquid chromatography, the conversion number (TON) of formic acid reached more than 8000; RuMnAl-LDH was prepared by coprecipitation method, and RuMnAl hydrotalcite catalyst was obtained by heating and activation in a muffle furnace. The preparation process is simple, and the raw materials are easy to obtain. The RuMnAl-LDH catalyst prepared by the application has good catalytic activity and stability in the catalytic hydrogenation of formic acid to formic acid reaction, and has wide application prospect.