5193 results about "Formic acid" patented technology

A forest fire retardant composition contains a retardant compound that includes a potassium salt. The potassium salt may include a potassium salt of an organic acid, a potassium salt of an inorganic acid, or mixtures thereof. The organic acid may include formic acid, acetic acid, propanoic acid, butanoic acid, lactic acid, oxalic acid, malic acid, gluconic acid, tartaric acid, uric acid, malic acid, or citric acid. The inorganic acid may include sulfuric acid, phosphoric acid, carbonic acid, or hydrochloric acid. The composition may be in the form of a dry concentrate, a liquid concentrate, or a final diluted product. The final diluted product is effective in suppressing, retarding, and controlling forest fires while exhibiting corrosion resistance and low toxicity.

The invention provides wafer-level reflow soldering equipment, belongs to the technical field of reflow soldering, and solves the problems that existing reflow soldering equipment is low in efficiency, poor in wafer reflow soldering treatment effect and the like. Comprising an EFEM system and a process area box arranged on the rear side of the EFEM system, two wafer loading and unloading machines are arranged on the front side of the EFEM system, a control system is arranged on the side portion of the EFEM system, a transfer robot and an equipment fan filter are arranged in the EFEM system, and a rotary welding system, a valve terminal box, a power box, a power distribution cabinet, an exhaust system and a formic acid storage tank are arranged in the process area box. The formic acid storage tank is connected with the rotary welding system through a pipeline, and an air inlet of the formic acid storage tank is connected with an external liquid nitrogen tank through a pipeline. According to the invention, the wafer can be stably carried and placed, temperature rise and temperature reduction suspension uniform heating treatment are carried out, rapid temperature reduction suspension uniform cooling treatment is carried out, positioning loading and auxiliary temperature reduction cooling treatment are realized, high wafer processing efficiency is ensured, and the processing effect is good.

The invention discloses a preparation method of a permanent red pigment for an acid and alkali resistant coating, and belongs to the technical field of pigment preparation, a 2B acid derivative is diazotized and then coupled with 2-hydroxy-3-naphthoic acid, then a calcium chloride aqueous solution is added for color lake to obtain pigment particles, and finally the surfaces of the pigment particles are coated with silicon dioxide to obtain the permanent red pigment for the acid and alkali resistant coating. According to the permanent red pigment for the acid and alkali resistant coating prepared by the preparation method disclosed by the invention, the acid and alkali resistance and environmental stability of the pigment are further enhanced while the excellent characteristics of original pigment red 48: 2 are maintained, and the application performance of the pigment is remarkably improved.

The invention discloses an antistatic polyisoprene rubber anesthesia air storage bag, and relates to the technical field of anesthesia air storage bags. The antistatic polyisoprene rubber anesthesia air storage bag is prepared from the following raw materials in parts by weight: 100 parts of polyisoprene latex, 0.5 to 2 parts of a stabilizer, 1 to 2 parts of a sodium p-styrenesulfonate aqueous solution, 3 to 6 parts of nano silicon dioxide suspension dispersion liquid, 1 to 2 parts of an anti-aging agent, 0.8 to 2 parts of conductive graphite and 3 to 6 parts of a vulcanization bag, the anti-aging agent is prepared by the following steps: reacting 3-(3, 5-di-tert-butyl-4-hydroxyphenyl) propionic acid with glycerol 1-oleyl ether-d5 to generate an esterification product, epoxidizing the esterification product with hydrogen peroxide and formic acid, and reacting the epoxidized product with N-phenyl-1, 3-phenylenediamine, and has excellent migration resistance. By adding the anti-aging agent into the polyisoprene rubber, the anti-aging capability of the anesthesia air storage bag is improved.

A method of increasing delivery of irrigation water and optionally a fertilizer to a predetermined depth in soil containing agricultural crops is disclosed. The method includes introducing formic acid to irrigation water to form a formate-enhanced irrigation water having a formate concentration of from about 10 ppm to about 10,000 ppm, and distributing the formate-enhanced irrigation water to the soil in an amount sufficient to (i) increase a flow rate of the irrigation water through the soil, (ii) reduce a compaction of the soil, and / or (iii) reduce a calcium concentration in the soil.

The invention relates to Omarlliptin, in particular to a novel method for preparing Istradafylline, and relates to a preparation method of Istradafylline, in particular to a preparation method of Istradafylline. The method comprises the following steps: carrying out coupling reaction on a compound Ia and TMS acetylene to obtain an intermediate Ib; carrying out bromination reaction on the intermediate Ic under the action of NBS (N-bromosuccinimide) to obtain an intermediate Id; carrying out substitution reaction on the intermediate Id and tert-butyl carbamate under the action of potassium tert-butoxide to obtain an intermediate Ie; reacting the intermediate Ie with paraformaldehyde to obtain an intermediate If; carrying out cycloaddition reaction on the intermediate If and the intermediate Ib to obtain a key intermediate Ig; carrying out asymmetric catalytic hydrogenation reduction on the intermediate Ig to obtain an intermediate Ih; and removing a protecting group from the intermediate Ih in a hydrochloric acid and ethyl acetate system to obtain a final product. The method is short in route, simple and convenient to operate, mild in condition, high in reaction yield, environment-friendly and easy for industrial production, and dangerous and highly toxic products are prevented from being used and hazardous chemicals are supervised. # imgabs0 #

The invention discloses a method for simultaneously detecting ergothioneine, ergosterol, ergosterol peroxide and lentinine in lentinus edodes, and belongs to the technical field of measurement of active ingredients of the lentinus edodes. The method comprises the following steps: detecting a shiitake mushroom extracting solution by adopting an ultra-high performance liquid chromatography-tandem mass spectrometry mode, wherein a chromatographic column is an HILIC or C18 chromatographic column; the mobile phase A and the mobile phase B are an aqueous solution containing formic acid and a methanol or acetonitrile solution containing formic acid respectively; the mass spectrum conditions comprise an electrospray ionization source; a positive ion multiple reaction monitoring mode; the ion spraying temperature is 315-325 DEG C; the temperature of the ion transmission tube is 320-330 DEG C; and the ion spraying voltage is 3500 V to 3700 V. The method has the characteristics of high sensitivity, high selectivity and high accuracy, and is suitable for quantitative detection of ergothioneine, lentinine, ergosterol peroxide and ergosterol compounds in shiitake mushrooms.

The present invention relates to a polyisocyanate composition comprising at least one bridging cistetrahydrofuran-2,5-diyl-dimethylene unit and at least one isocyanurate, iminooxadiazinedione, allophanate, urethane, urea, uretdione, oxadiazinetrione, carbodiimide, thiourethane, thioallophanate and / or biuret structure and / or comprising at least one bridging trans-tetrahydrofuran-2,5-diyl)-dimethylene unit and at least one isocyanurate, iminooxadiazinedione, allophanate, urethane, urea, uretdione, oxadiazinetrione, carbodiimide, thiourethane, thioallophanate and / or biuret structure.

The invention discloses a preparation method of a GLP-1R agonist Orforglipron, which comprises the following reaction steps: carrying out four-step reaction on an oxopiperidine compound (1) and (4-fluoro-3, 5-dimethylphenyl) hydrazine (2) to obtain a compound 8, and carrying out seven-step reaction on 5-bromo-indolecarboxylic acid (9) to obtain a compound 17. Then, the compound 8 and a compound 17 are subjected to an acid amine condensation reaction, and Orforglipron (LY3502970) is obtained. The preparation method is relatively low in cost, easy to operate, relatively short in synthetic route and suitable for industrial production and application, and the total yield can reach 32%.

The invention discloses a formate dehydrogenase mutant and application of the formate dehydrogenase mutant in catalysis of carbon dioxide reduction, the 223 arginine (Arg) of an amino acid sequence of formate dehydrogenase PsFDH48 derived from Paracoccus sp. MKU1 is mutated into proline (Pro) or the 242 proline (Pro) is mutated into phenylalanine (Phe) through a site-specific mutagenesis technology, and the obtained mutants R223P and P242F have higher catalytic activity and can be applied to catalysis of carbon dioxide reduction. The catalyst can catalyze CO2 to generate formic acid more effectively in vitro, and has potential application value in the aspects of efficient activation of CO2 and further conversion of CO2 into other mono-carbon compounds through cascade reaction.

The invention relates to a ceramic coating for a gravure etching pot and a coating method of the ceramic coating, and belongs to the technical field of ceramic coatings. The ceramic coating comprises the primer and the finish paint, and the nano silicon dioxide sol, the inorganic pigment and the modified silicon dioxide filler in the primer jointly form a firm primer layer, so that the adhesive force of the coating and a base material is enhanced, and meanwhile, the wear resistance of the coating is improved; the reticular molecular structure of polysiloxane is stable at high temperature, so that the overall temperature resistance of the coating is improved; by adding the hollow glass beads, the density and hardness of the coating can be adjusted, and meanwhile, the heat insulation performance of the coating can be improved; the viscosity of the coating can be optimized by adjusting the contents of formic acid and deionized water, so that the coating is easier to construct and coat; and the polydimethylsiloxane is added into the finish paint, so that the non-stickiness of the coating is remarkably improved, and the surface is smoother and is easy to clean.

The invention belongs to the technical field of water-soluble polymer synthesis and drilling fluid application, and relates to a salt-resistant and high-temperature-resistant polymer micro-manganese dispersing agent as well as a preparation method and application thereof. The invention relates to a preparation method of a salt-resistant and high-temperature-resistant polymer micro-manganese dispersant. The preparation method comprises the following steps: dissolving a carboxylic acid-containing monomer and a sulfonic acid-containing monomer in deionized water; dropwise adding a first functional monomer and a second functional monomer, and then adjusting the pH to be neutral to obtain a mixed solution; introducing nitrogen and heating, adding an initiator aqueous solution after the mixed solution is heated to a preset temperature, and obtaining a polymer solution after the reaction is finished; and dropwise adding the polymer solution into a mixed solution of ethanol and acetone, and filtering to obtain the salt-resistant and high-temperature-resistant polymer micro-manganese dispersing agent. The salt-resistant and high-temperature-resistant polymer micro-manganese dispersing agent is small in dosage and good in effect, when 40% potassium formate water and the micro-manganese content are 36%, only 0.2 wt% of the dispersing agent is used, hot rolling can be conducted for 16 h at the temperature of 210 DEG C, and the viscosity reduction effect is kept to be 40% or above.

The invention discloses a large-size power chip no-pressure low-void-ratio welding method, which comprises the following steps of: determining proper thickness and size of a soldering lug according to the size of a chip and the material of a substrate; then cutting and carrying out plasma cleaning on the soldering lug to remove dirt on the surface of the soldering lug; welding sample assembly is completed through an automatic chip mounter; setting a vacuum welding curve according to the material characteristics of the welding sheet, determining key welding parameters such as formic acid pressure, formic acid reduction temperature, formic acid reduction time, peak temperature, peak temperature holding time, furnace chamber pressure and holding time and the like, and completing chip welding according to the set curve; and finally, measuring the internal void ratio of the welding seam by adopting an X-ray detector. On the basis of the vacuum eutectic welding technology, under the non-pressure welding condition, the air holes in the welding flux layer are discharged by regulating and controlling the environment pressure change in the welding process, and low-void-ratio welding of the large-size chip is achieved.

The invention provides triazole anthracene methyl formate for a photosensitive resin composition, and relates to the field of photopolymerization. The invention also comprises a photosensitive resin composition containing the triazole anthracene methyl formate, a photosensitive dry film containing the triazole anthracene methyl formate, and applications of the photosensitive resin composition and the photosensitive dry film. The triazole formic acid anthracene methyl ester disclosed by the invention has photosensitivity, can be used as a photosensitizer in the photosensitive resin composition, can improve the adhesive force of the photosensitive resin composition on various metal surfaces, and has the characteristic of low migration; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The invention relates to a method for synthesizing tetrasubstituted-1, 3-allene dicarboxylic acid, and discloses a method for synthesizing tetrasubstituted-1, 3-allene dicarboxylic acid by taking 1, 3-enyne and iodide as raw materials, potassium formate as a formate source, DABCO as a hydrogen transfer catalyst, Ir (bpy) 2 (dtbpy) PF6 as a photocatalyst and cesium carbonate as alkali through the following steps: introducing CO2 at normal pressure; the allene dicarboxylic acid compound can be obtained at excellent to good yield under the irradiation of visible light at room temperature for 24 hours, the reaction condition is mild, the regioselectivity is good, the functional group tolerance is good, and many defects in the prior art are overcome.

The invention relates to an electrolyte for an aqueous zinc ion battery and the zinc ion battery. The electrolyte consists of soluble zinc salt, an electrolyte additive and solvent water, and the electrolyte additive is a thiazole derivative containing functional groups such as sulfydryl, amino, sulfonic acid group and formic acid group. According to the electrolyte provided by the invention, the electrolyte additive can regulate and control the coordination environment through coordination with zinc ions so as to realize uniform deposition of zinc, meanwhile, the electrolyte additive can also be grafted to the surface of zinc through functional groups such as sulfydryl, amino, sulfonic acid group and formic acid group so as to form a layer of stable protective film, and the protective film has good zinc affinity; direct contact between an electrolyte and the zinc negative electrode can be effectively blocked, chemical corrosion and hydrogen evolution reaction of the zinc negative electrode can be reduced, interface ion transmission can be regulated and controlled, zinc dendrite growth is effectively inhibited, the cycling stability of the zinc negative electrode is improved, the cycle life of the battery is prolonged, the rate performance of the battery is improved, and the method is easy and convenient to prepare, low in cost, high in safety and suitable for industrial production. The large-scale production is easy to realize.

The invention belongs to the field of biological pharmacy and biological conversion, and particularly relates to a lipase mutant and application thereof. The lipase CALB mutant disclosed by the invention is obtained by carrying out single-point mutation or combined mutation on the 40th site, the 134 site, the 154 site, the 189th site, the 278th site and the 281 site of an amino acid sequence as shown in SEQ ID NO.1. Compared with a wild type, the mutant has the advantage that the stereoselectivity is greatly improved when the mutant is used for catalyzing racemization 3-cyclohexene-1-methyl formate to produce (S)-3-cyclohexene-1-formic acid. Compared with a traditional chemical method for preparing (S)-3-cyclohexene-1-formic acid, the lipase CALB mutant provided by the invention is high in stereoselectivity, mild in reaction condition, environment-friendly, low in equipment requirement, capable of greatly reducing the production cost and wide in application prospect in industrial application.

The invention belongs to the technical field of mine filling materials, and discloses a solid-waste-based mine filling material and a preparation method thereof. The filling material comprises 70-100 parts of red mud, 1-10 parts of fly ash, 1-10 parts of slag, 5-20 parts of an acid activator, 10-30 parts of aggregate, 1-5 parts of a water reducing agent and 50-100 parts of water. The doping amount of the red mud of the filling material can reach 60% or above, the red mud is used as a main cementing material, formic acid, acetic acid, oxalic acid and other small-molecular organic acids are used as an acid activator, and an acid environment provided by the acid activator can reduce the alkalinity of the red mud and promote the dissolution of the red mud; the water and calcium silicate in the red mud can be more easily subjected to hydration reaction to generate a large amount of hydration products such as C-S-H gel, so that the strength of the filling material is enhanced. The acid activator used in the invention is low in cost, the cementing material and the aggregate are industrial solid wastes, and the cost of the mine filling material is reduced while the problem of resource utilization of the industrial solid wastes is solved.

The invention relates to the field of organic chemical synthesis, in particular to a synthetic method and application of pyrimidone compounds. The invention provides a synthesis method, reactants are o-amino heterocyclic formamide and triethyl orthoformate respectively, a solvent system is a hexafluoroisopropanol solvent, and a product is a heterocyclic pyrimidone compound. The reaction does not need strong acid or strong alkali conditions, does not need additional reducing agents or oxidizing agents, does not need transition metal catalysis, is economical and practical, the reaction conditions are relatively mild, and the synthesized pyrimidone compound has a good antibacterial effect.

The invention discloses an implantable passive pressure sensor and a preparation method thereof. The passive pressure sensor comprises electrode layers, a dielectric layer clamped between the electrode layers and a packaging layer wrapping the electrode layers, the electrode layers are coils made of patterned conductor materials, and the dielectric layer and the packaging layer are both made of silk fibroin films; the method comprises the following steps: dissolving degummed silk in a halide salt-formic acid solution to obtain a regenerated silk fibroin solution, curing the regenerated silk fibroin solution at room temperature to form a silk fibroin gel film, then freeze-drying the silk fibroin gel film to obtain a porous silk fibroin film, and preparing a dielectric layer and a packaging layer by using the porous silk fibroin film. And packaging the patterned conductor material between the dielectric layer and the packaging layer. The silk fibroin is used for preparing the sensing device, the overall degradation rate of the device can be more conveniently regulated and controlled, synchronous degradation of all parts of the device is ensured, short-term monitoring of pressure sensing is achieved, and secondary taking-out operation is not needed after implantation.

The invention provides a construction method and application of a fingerprint spectrum of a dampness-removing stomach-poria cocos decoction, and belongs to the technical field of drug detection.The construction method comprises the steps that the dampness-removing stomach-poria cocos decoction is used for preparing a test solution, and then the fingerprint spectrum of the dampness-removing stomach-poria cocos decoction is obtained through high performance liquid chromatography detection with acetonitrile (A)-0.18-0.22 wt% formic acid aqueous solution as a mobile phase; a standard fingerprint spectrum is established by adopting a traditional Chinese medicine chromatographic fingerprint spectrum similarity evaluation system and is used for quality evaluation or control in the whole process of research / development / production / clinical application of the dampness-removing stomach-poria decoction. According to the construction method of the fingerprint spectrum of the dampness-eliminating stomach-poria cocos decoction, main medicinal material components in the dampness-eliminating stomach-poria cocos decoction can be detected only through high performance liquid chromatography, so that the quality condition of the dampness-eliminating stomach-poria cocos decoction can be reflected more comprehensively.

The invention discloses a synthesis method of 2-bromomethyl-5-trifluoromethyl furan, which comprises the following steps: S1, carrying out reaction on acetoacetate and halogenated trifluoroacetone under the action of an alkaline substance and a catalyst to generate a 2-acetyl-5, 5, 5-trifluoro-4-oxovalerate crude product; s2, carrying out a cyclization reaction on the 2-acetyl-5, 5, 5-trifluoro-4-oxovalerate crude product, so as to obtain a 2-methyl-5-(trifluoromethyl) furan-3-formate crude product, and carrying out a cyclization reaction on the 2-acetyl-5, 5, 5-trifluoro-4-oxovalerate crude product to obtain a 2-methyl-5-(trifluoromethyl) furan-3-formate crude product; s3, adding an alkaline substance into the crude product, carrying out hydrolysis, and adding acid to adjust the pH value after the hydrolysis is completed, so as to obtain 2-methyl-5-(trifluoromethyl) furan-3-formic acid; s4, the 2-methyl-5-(trifluoromethyl) furan-3-formic acid is subjected to a heating decarboxylation reaction, and 2-methyl-5-(trifluoromethyl) furan is obtained; and S5, carrying out a bromination reaction on the 2-methyl-5-(trifluoromethyl) furan and a bromination reagent to obtain a final product 2-bromomethyl-5-(trifluoromethyl) furan. The raw materials used in the synthesis method are easy to obtain, use of control chemicals is not involved, and industrialization is easy to achieve.

The invention relates to the technical field of adhesives, and particularly discloses an electrogenerated viscosity-reducing adhesive as well as a preparation method and application thereof. The electrogenerated viscosity-reducing glue is prepared from the following raw materials in parts by weight: 100 to 150 parts of polyacrylate, 30 to 50 parts of polyvinyl alcohol, 20 to 40 parts of functional monomer, 1 to 5 parts of conductive agent, 2 to 6 parts of alkenyl-containing ionic liquid, 1 to 5 parts of lithium salt, 1 to 5 parts of tackifier, 1 to 2 parts of dispersant, 0.1 to 2 parts of initiator and 60 to 100 parts of organic solvent, and the conductive agent is obtained by synergistically modifying hydroxylated carbon nanotubes with 2-thiophenecarboxylic acid and 2-picolinic acid. The electrogenerated viscosity-reducing adhesive is applied to the electrogenerated viscosity-reducing adhesive tape, and the obtained adhesive tape is excellent in peel strength and shear strength, high in power-on viscosity-reducing efficiency, free of adhesive residue during peeling, reusable and wide in application prospect.

The invention relates to the field of conveying, in particular to a gap bridge conveying mechanism and a formic acid furnace. The gap bridge conveying mechanism comprises a first conveying line, a second conveying line and a gate gap bridge unit, and the first conveying line is configured in the first furnace chamber so as to convey trays; the second conveying line is configured in the second furnace chamber so as to convey the trays; the gate gap bridge unit is arranged between the first furnace chamber and the second furnace chamber and comprises a supporting bridge, an elastic element, a door frame, a gate and an opening and closing power assembly. The opening and closing power assembly is used for driving the gate to move so as to open or close the door hole. The supporting bridge is movably arranged in the door frame; the elastic element is used for applying elastic force to the supporting bridge to enable the supporting bridge to reach a working position; and the supporting bridge at the working position is used for supporting a tray which is transferred between the first conveying line and the second conveying line and passes through the door hole. Trays can be stably conveyed between the first conveying line and the second conveying line, and the positions of products in the trays are prevented from being changed.

The invention belongs to the technical field of liquid chromatography-mass spectrometry detection pretreatment, and particularly relates to a pretreatment method for liquid chromatography-tandem mass spectrometry analysis of pesticide and veterinary drug residues in serum, which comprises the following steps: (S1) carrying out heating reaction on Sc (III) salt, Cu (II) salt and 1H-pyrazole-4-formic acid (H2PyC) in a polar aprotic solvent, and cooling to obtain a green crystal, namely MOF-919; the chemical formula of the MOF-919 is [Sc < 3 > (mu3-O) (OH) < 3 >] [Cu3 (mu3-O) (mu-PyC) < 3 > (H2O) < 6 >] < 2 >; (S2) mixing the serum sample with an acetonitrile solution containing formic acid, carrying out ultrasonic treatment, vortex oscillation and centrifugation, taking supernate, and diluting the supernate with an aqueous solution containing formic acid to obtain a to-be-purified solution; and (S3) adding MOF-919 into the to-be-purified liquid, mixing, performing ultrasonic treatment, performing vortex oscillation, centrifuging, and taking supernate, thereby completing the pretreatment of the to-be-purified liquid. According to the method, the MOF-919 is used for adsorbing chemical pollutant residues in serum, especially phospholipids, so that the purpose of removing the chemical pollutant residues in blood is achieved. The method is simple and convenient to operate, small in organic solvent consumption and good in purification effect, and can be widely applied to residue analysis of chemical pollutants in serum.

The invention relates to a method and device for preparing formic acid and hydrogen through electrolysis. According to the method, an alkaline electrolyte containing methanol is electrolyzed, a cathode electrode for electrolysis takes foamed nickel as a base material to load iron-cobalt-nickel nanoparticles, an anode electrode takes foamed nickel as a base material to load cobalt-nickel particles, and a cathode chamber generates hydrogen; and collecting the electrolyte obtained after electrolysis in the anode chamber in the electrolysis device for bipolar membrane electrodialysis, and obtaining a primary formic acid solution in the acid chamber of the bipolar membrane electrodialysis device. The device comprises an electrolysis device and a bipolar membrane electrodialysis device, a cathode electrode, a first bipolar membrane, a positive membrane, a negative membrane, a second bipolar membrane and an anode electrode are sequentially arranged in the bipolar membrane electrodialysis device, and an acid chamber, a salt chamber and an alkali chamber are sequentially divided among the first bipolar membrane, the positive membrane, the negative membrane and the second bipolar membrane. Compared with an existing methyl formate hydrolysis method for preparing formic acid, an intermediate methyl formate is toxic to a human body, formic acid and hydrogen can be safely prepared, and production safety accidents are prevented.

The invention belongs to the technical field of nanocrystal nucleus early strength agents, and provides a damp and hot nanocrystal nucleus early strength agent, a tailing solidification filling material and a preparation method and application of the damp and hot nanocrystal nucleus early strength agent and the tailing solidification filling material. The invention discloses a molybdenum ore tailing slurry which is prepared from the following raw materials in parts by weight: 1 part of Portland cement, 4 to 6 parts of molybdenum ore tailings, 0.06 to 0.1 part of zeolite powder, 0.07 to 0.1 part of nanoscale attapulgite powder, 0.06 to 0.1 part of gamma-glycidyl ether oxypropyl trimethoxy silane, 0.03 to 0.1 part of potassium silicate, 0.04 to 0.1 part of sodium hydroxide, 0.06 to 0.1 part of calcium formate, 0.04 to 0.1 part of lithium metaaluminate and 1.25 to 1.75 parts of water. According to the technical scheme, the problem that a filling body prepared from an early strength agent in the prior art is low in early and later strength is solved, and meanwhile, the early strength agent is simple and convenient in preparation mode, low in cost and wide in application range.

The invention discloses a construction method and an identification method of characteristic chromatograms of a senecio scandens medicinal material as well as decoction pieces, standard decoction and formula granules thereof, and relates to the technical field of traditional Chinese medicine identification. The construction method of the specific chromatogram comprises the following steps: extracting a to-be-detected sample with methanol to obtain a test solution; the method comprises the following steps: dissolving 5-caffeoylquinic acid, chlorogenic acid, caffeic acid, 4-caffeoylquinic acid, rutin, hyperoside, isoquercitrin and 4, 5-dicaffeoylquinic acid with methanol to obtain a reference solution; and a liquid chromatograph is adopted for determination. A chromatographic column of the liquid chromatograph takes phenyl-methyl polysiloxane as a stationary phase, acetonitrile as a mobile phase A and 0.05 vol%-0.3 vol% formic acid aqueous solution as a mobile phase B for gradient elution. The information of the characteristic chromatogram constructed by the method is rich, and the quality of the senecio scandens medicinal material, decoction pieces, standard decoction and formula granules can be quickly and comprehensively reflected.

The disclosure provides a catalyst reaction mixture including a ligand having a backbone with at least one phosphorus atom and at least one nitrogen atom, a chromium compound, and a solvent mixture including decalin and at least one additional solvent, wherein the solvent mixture comprises decalin in an amount of less than 20 wt. % and, optionally, perhydroindane in an amount of 50 wt. % or less, based on the total weight of the solvent mixture. A method of forming a linear alpha olefin through ethylene oligomerization is also provided, the method including contacting ethylene gas with a reaction mixture in a reactor, the reaction mixture including the catalyst reaction mixture of the disclosure; and withdrawing a product stream including at least one linear alpha olefin, such as 1-butene, 1-hexene, or 1-octene, from the reactor.

The invention discloses a preparation method of 6-methyl-5-octylene-2-ketone, and belongs to the technical field of organic synthesis. According to the method, 5-chloro-2-pentanone is taken as a starting raw material, carbonyl protection is carried out with trimethyl orthoformate under the catalysis of acid, then a Grignard reagent is prepared, condensation dehydration is carried out on the Grignard reagent and 2-butanone, deprotection is carried out under the acidic condition, and 6-methyl-5-octylene-2-ketone is prepared with high yield, the raw materials are easy to obtain and low in price, and the reaction can be catalyzed by using a conventional catalyst.