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38 results about "Biomedical implant" patented technology

Implant tooth guiding device and method for biomedicine

The invention relates to the technical field of implant teeth, in particular to a biomedical implant tooth guiding device and method.The biomedical implant tooth guiding device comprises a positioning base plate, the positioning base plate is clamped to the outer side of a gum through a positioning clamping groove, guiding plates are oppositely arranged on the two sides of a tooth implantation point position, and the ends, located on the tongue side, of the two guiding plates are fixedly connected to the positioning base plate; an opening is formed in the positioning base plate on the cheek side at the tooth implantation point, a guide block is arranged between the two guide plates in a sliding and penetrating manner, and one end, on the tongue side, of the guide block is detachably connected with the positioning base plate through a lock catch assembly; the positioning block can be quickly inserted, pulled and replaced, drill rods with different diameters are all provided with brand-new guide holes, the center lines of the drill rods are highly overlapped, and tooth implantation point positions are completely exposed after the drill rods are moved out and are convenient to clean; the spiral diversion trench and the drill rod form a cooling channel matched with a liquid suction channel, so that cooling liquid is rapidly conveyed and cooled, and waste liquid is timely removed; the clamping assembly is arranged to be integrally assembled outside the oral cavity and then fed into the mouth for accurate positioning at a time.
Owner:HUBEI PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE (AFFILIATED HOSPITAL OF HUBEI UNIV OF TRADITIONAL CHINESE MEDICINE HUBEI INST OF TRADITIONAL CHINESE MEDICINE)

Mechanical metamaterial cell element with zero Poisson's ratio property

The invention discloses a mechanical metamaterial cell element with a zero Poisson's ratio property, and belongs to the technical field of mechanical metamaterials. The upper top plate and the lower bottom plate are symmetrically arranged, the upper cleat nail set and the lower cleat nail set are arranged at the four corners of the inner side faces of the upper top plate and the lower bottom plate, the elastic body set is connected through the upper cleat nail set and the lower cleat nail set, and the flexible hinge component set is arranged at the midpoint position of four side lines of the upper top plate and the lower bottom plate. The flexible hinge component set keeps inward pre-bending through the pre-tension of the elastomer set, and when the cell element bears an axial load, the flexible hinge component set generates coordinated inward bending deformation, so that the cell element shrinks in the axial direction, the transverse size is kept stable, the axial zero Poisson's ratio characteristic is achieved, and meanwhile the energy absorption capacity is achieved. The cell element is based on elastic deformation, has self-recovery capability and long cycle life, adopts modular design, is convenient to assemble, disassemble and maintain, and is suitable for application scenes of aerospace buffer devices, biomedical implants, precise instrument supporting structures and the like.
Owner:CHANGCHUN UNIV OF TECH

Heterostructure high-strength hydrogen embrittlement-resistant commercial pure titanium and preparation method thereof

The invention relates to the technical field of hydrogen embrittlement resistance of metal materials, in particular to high-strength hydrogen embrittlement-resistant commercial pure titanium with a heterostructure and a preparation method thereof. The microstructure of the pure titanium is a heterostructure jointly formed by coarse grains, fine grains, ultra-fine grains, nanocrystalline and high-density deformation twin crystals, and the grain boundary structure of the pure titanium comprises small-angle grain boundaries and twin boundaries. An original pure titanium bar is subjected to multi-pass rotary forging deformation at the liquid nitrogen temperature, the deformed pure titanium is annealed, and the pure titanium which has heterostructures with different grain sizes and contains strong < 0001 > / / stretching direction (TD) fiber textures, a large number of small-angle grain boundaries and high-density deformation twin crystals is obtained. According to the method, the commercial pure titanium with high strength and plasticity matching and good hydrogen embrittlement resistance is obtained by combining rotary forging processing and simple annealing treatment on the commercial pure titanium, the method has the advantages of being high in operability and the like, and a new material choice is provided for design and manufacturing of high-performance ocean engineering equipment and biomedical implants.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI

Morphology-controllable mesoporous nano-hydroxyapatite microspheres, preparation method and application thereof

PendingCN122276688AMicrosphereBiocompatibility
This invention relates to the field of biomaterial preparation technology, and in particular to a morphology-controllable mesoporous hydroxyapatite nanosphere, its preparation method, and its applications. The preparation method includes: S1, mixing an aqueous solution of pyridoxal phosphate with an aqueous solution of calcium chloride, adjusting the pH of the mixed solution to 7-11 to obtain a precursor solution; S2, placing the precursor solution in a microwave reactor for reaction to obtain mesoporous hydroxyapatite nanospheres. The preparation method provided by this invention is simple, the reaction conditions are easily controlled, and it is highly safe and reliable. It enables precise control of the morphology and particle size of the hydroxyapatite microspheres, and the prepared product exhibits excellent biocompatibility and structural regularity. It has good industrial application prospects in the field of biomedical implants such as bone tissue repair and is suitable for large-scale production.
Owner:BEIJING UNIV OF TECH

Magnesium-based medical material containing CaP-CS / diamond-like carbon composite coating as well as preparation method and application of magnesium-based medical material

The invention discloses a magnesium-based medical material containing a CaP-CS / diamond-like carbon composite coating and a preparation method and application thereof.The magnesium-based medical material is composed of a magnesium alloy, the diamond-like carbon coating and the CaP-CS coating, the diamond-like carbon coating is attached to a magnesium alloy substrate, and the CaP-CS coating is attached to the diamond-like carbon coating. The method comprises the following steps: preparing a diamond-like coating on the surface of a magnesium alloy substrate, and soaking the diamond-like coating in a CaP-CS solution to obtain the magnesium-based medical material containing the CaP-CS / diamond-like composite coating. According to the composite coating structure, high hardness and chemical inertness of the diamond-like coating and excellent biocompatibility and osteoinductivity of the CaP-CS coating are integrated, collaborative optimization of corrosion resistance and biocompatibility of the magnesium alloy is achieved, good film-substrate binding force is achieved, and application of the magnesium alloy in the field of biomedical implant materials is promoted.
Owner:XIANGTAN UNIV

A zinc-based alloy composite material and a preparation method and application thereof

PendingCN122279320AZinc alloysAlloy composite
This invention relates to the field of metal matrix composite material preparation technology, specifically to a zinc-based alloy composite material and its preparation method, particularly applicable to the field of biodegradable biomedical implant materials. The zinc-based alloy composite material comprises a zinc alloy matrix and nano-reinforcing particles. The zinc alloy matrix is ​​composed of Zn, Cu, and Li; wherein the mass percentage of Cu in the zinc alloy matrix is ​​1-2 wt%, and the mass percentage of Li in the zinc alloy matrix is ​​0.1-0.9 wt%; the volume percentage of the nano-reinforcing particles in the zinc alloy matrix is ​​<2.5 vol%; the particle size of the nano-reinforcing particles is <100 nm, and the nano-reinforcing particles are uniformly dispersed in the zinc alloy matrix. The invention also relates to the preparation and application of the above-mentioned zinc-based alloy composite material. This invention solves the problems of unstable microstructure and difficulty in balancing strength and ductility in existing zinc-copper-lithium alloys, thus improving the mechanical properties of the zinc-copper-lithium alloy system.
Owner:SICHUAN KEZINKANG BIOTECHNOLOGY CO LTD

Biodegradable zinc-based materials including dispersed nanostructures for biomedical applications

A biomedical device includes a zinc-based material including a matrix including zinc, and nanostructures dispersed in the matrix. Embodiments of this disclosure are directed to zinc (Zn)-based materials including dispersed nanostructures for biomedical applications and devices, such as bioresorbable vascular stents, bioresorbable ureteral stents, endoluminal springs for distraction enterogenesis, biodegradable bone implants with tunable modulus, guided bone generation membranes, bioresorbable dental membranes, and other biomedical implants, as well as other functional applications, such as biodegradable electronics and sensors.
Owner:RGT UNIV OF CALIFORNIA

Preparation method of gradient-structure titanium-based composite material

The invention discloses a gradient structure titanium-based composite material and a preparation method thereof. The preparation method comprises the following steps: performing high-energy ball milling and mixing on titanium powder and reinforced phase powder (at least one of TiB, TiC or TiB with the particle size of 0.5-5 microns) according to different mass fractions (5-30 wt%); preparing a core wire with low content (5-10 wt%) of composite powder through cold isostatic pressing and hot extrusion; a double-barrel powder feeding system (respectively loaded with high-content composite powder and pure titanium powder) is adopted for coaxial laser cladding, and the powder feeding speed is dynamically regulated and controlled to realize gradient distribution of a reinforced phase; and then hot isostatic pressing interface strengthening, multi-pass equal-channel angular pressing refining and high-energy shot peening surface strengthening are carried out. Optionally, laser shock peening and chemical vapor deposition of a TiN coating can also be carried out. The obtained material has a gradient structure of a core part (low-content reinforced phase), a transition layer (gradient change) and a surface layer (high-content reinforced phase), and the microstructure has the characteristics of nanocrystalline (surface layer), ultra-fine crystal (transition layer) and isometric crystal (core part). The room-temperature tensile strength of the material is not less than 1200 MPa, the ductility is not less than 8%, and the surface hardness is not less than 600 HV; the tensile strength at the high temperature of 600 DEG C is larger than or equal to 800 MPa, the creep life is larger than or equal to 500 h (under the load of 300 MPa), the interface bonding strength is high (larger than or equal to 350 MPa), and the alloy is suitable for the fields of aero-engine blades, spacecraft structural parts, biomedical implants and the like.
Owner:JIANGSU UNIV

Porous diamond reinforced polylactic acid composite bone scaffold and preparation method thereof

The invention discloses a porous diamond reinforced polylactic acid composite bone scaffold and a preparation method thereof, and belongs to the technical field of biomedical implants. The stent is integrally formed through a selective laser sintering technology and is composed of a polylactic acid matrix and porous diamonds uniformly dispersed in the polylactic acid matrix, and the mass fraction of the porous diamonds is 2%-16%. The surface of the porous diamond is rich in porous structures and oxygen-containing functional groups, the porous diamond and a polylactic acid matrix form a molecular bonding and mechanical interlocking synergistic enhancement interface, and the mechanical property of the polylactic acid composite bone scaffold is remarkably improved. The preparation method comprises the following steps: (1) weighing polylactic acid powder and porous diamond powder according to a set proportion, and uniformly mixing through vacuum ball milling to obtain composite powder; and (2) performing selective laser sintering on the composite powder in an argon protective atmosphere, and integrally forming to obtain the composite bone scaffold. The problem that traditional diamond particle reinforced phase interface bonding is weak is solved, and the method has wide application prospects in the field of bone tissue engineering.
Owner:CHANGSHA UNIVERSITY

Method for connecting Bi-In-Sn liquid metal coating and titanium alloy matrix

The invention discloses a method for connecting a Bi-In-Sn liquid metal coating and a titanium alloy matrix, and belongs to the technical field of liquid metal application, and the method comprises the following steps: carrying out mechanical polishing on a to-be-connected surface of the titanium alloy matrix to remove an oxide layer and pollutants; the pretreated to-be-connected area is completely wrapped with a low-melting-point Bi-In-Sn alloy; the Bi-In-Sn alloy is heated to 700 DEG C in the inert gas protection atmosphere, heat preservation is conducted for 6 hours, the Bi-In-Sn alloy is molten and fully interdiffused with a titanium alloy matrix, and a compact and continuous diffusion bonding layer is formed; and after cooling, redundant alloy is removed, and then the Bi-based coating is prepared on the diffusion bonding layer through coating, spraying or electroplating. According to the method, the bonding strength of the Bi-based coating and the titanium alloy matrix can be remarkably improved, the interface is free of cracks, holes and other defects, the process stability is high, the adaptability is high, and the application requirements in the fields of biomedical implants, electronic heat management, flexible electronics and the like can be met.
Owner:BEIHANG UNIV +1

Supramolecular biomedical polymers

The present invention relates to supramolecular biomedical polymers comprising quadruple hydrogen bonding units and to a process for preparing such a supramolecular biomedical polymer and porous biomedical implants thereof. The supramolecular biomedical polymers are particularly suitable for the production of porous biomedical implants that need high strength, elasticity, durability, and slow biodegradation, e.g. medical implants for living tissue regeneration within a mammal, such as the treatment of cardio-vascular diseases, medical prolapses, and hernias.
Owner:SUPRAPOLIX

A Mo-Mn biodegradable molybdenum alloy, its preparation method and application

This invention discloses a Mo-Mn biodegradable molybdenum alloy, its preparation method, and its applications. The alloying elements include Mo and Mn, with Mn accounting for >0-30% by mass, and the remainder being Mo. Manganese-doped molybdenum powder is prepared by wet chemical methods or mechanical alloying. The manganese-doped molybdenum powder is then subjected to hot pressing sintering or multi-step spark plasma sintering to obtain the Mo-Mn alloy. The Mo-Mn biodegradable molybdenum alloy of this invention possesses excellent mechanical properties, providing long-term effective mechanical support in vivo, and exhibits good cell compatibility, blood compatibility, and tissue / organ compatibility, making it suitable for use as a biomedical implant.
Owner:PEKING UNIV

Silicon nitride / magnesium silicon nitride powder with core-shell structure as well as preparation method and application of silicon nitride / magnesium silicon nitride powder

ActiveCN121553909ANitrogen-metal/silicon/boron binary compoundsImplantBiomedical implant
The invention relates to core-shell structure silicon nitride / silicon magnesium nitride powder as well as a preparation method and application thereof, and belongs to the technical field of structural ceramic materials. The method comprises the following steps: providing silicon nitride powder, and carrying out oxidation pretreatment to obtain silicon nitride pretreated powder with an oxidation film layer on the surface; magnesium powder is provided and heated to form magnesium steam, the silicon nitride pretreated powder is placed in a mixed atmosphere containing nitrogen and the magnesium steam to be subjected to a high-temperature sintering reaction, and composite powder is obtained; and carrying out residual magnesium removal treatment on the composite powder, and calcining to obtain the core-shell structure silicon nitride / silicon magnesium nitride powder. The silicon nitride / silicon magnesium nitride powder with the core-shell structure takes silicon nitride as a core and silicon magnesium nitride as a shell, has the advantages of promoting low-temperature high-density sintering of silicon nitride and improving the purity and performance of ceramic, and is suitable for the fields of aerospace engine parts, precision mechanical shaft pumps, cutting tools, biomedical implants, electronic packaging thermal management materials and the like.
Owner:YONGJIANG LAB

Core-shell structure silicon nitride / silicon nitride magnesium powder, preparation method and application thereof

The application relates to a core-shell structure silicon nitride / silicon nitride magnesium powder and a preparation method and application thereof, and belongs to the technical field of structural ceramic materials. The method comprises the following steps: providing silicon nitride powder, performing oxidation pretreatment to obtain silicon nitride pretreated powder with an oxidation film layer on the surface; providing magnesium powder, heating to form magnesium vapor, and placing the silicon nitride pretreated powder in a mixed atmosphere comprising nitrogen and the magnesium vapor to perform high-temperature sintering reaction, so as to obtain a composite powder; and performing residual magnesium removal treatment on the composite powder, and performing calcination to obtain the core-shell structure silicon nitride / silicon nitride magnesium powder. The core-shell structure silicon nitride / silicon nitride magnesium powder takes silicon nitride as a core and silicon nitride magnesium as a shell, has the advantages of promoting low-temperature high-density sintering of silicon nitride, improving ceramic purity and performance, and is suitable for fields of aerospace engine components, precision mechanical shaft pumps, cutting tools, biomedical implants and electronic packaging thermal management materials.
Owner:YONGJIANG LAB

A method for preparing Zr-2.5Nb alloy by hot pressing and sintering coarse-grained pre-alloyed spherical powder below the β phase transformation temperature.

This invention discloses a method for preparing Zr-2.5Nb alloy by hot-pressing sintering coarse-grained pre-alloyed spherical powder below the β phase transformation temperature. The method includes: 1. Selecting coarse-grained spherical Zr-2.5Nb alloy pre-alloyed powder prepared by the plasma rotating electrode method as raw material; 2. Placing the raw material into a mold and placing it in a hot press furnace under vacuum; 3. Heating to a temperature below the β phase transformation temperature of Zr-2.5Nb alloy and holding at that temperature for hot-pressing sintering; 4. Cooling to room temperature to obtain a dense Zr-2.5Nb alloy. This invention utilizes the characteristics of coarse-grained spherical Zr-2.5Nb alloy pre-alloyed powder—namely, its fine grain structure, crystal defects, and metastable α′ martensitic phase transformation activity—to achieve efficient densification at lower temperatures and suppress grain coarsening, resulting in a Zr-2.5Nb alloy material with uniform structure, high density, and excellent overall performance, suitable for the field of biomedical implants.
Owner:NORTHWEST INSTITUTE FOR NONFERROUS METAL RESEARCH

Method for manufacturing biomedical implant, and biomedical implant

PCT designated stageWO2026070920A1StentsBiomedical engineeringImplant
A method for manufacturing a biomedical implant (100) comprises a circumferential diameter reduction step for preparing a porous structure for use in a biological implant, which is to include a diameter-expandable tubular stent (10) and a porous structure (20) arranged to cover the stent and configured to expand as the stent expands, and reducing the diameter of the porous structure in the circumferential direction from a state where the porous structure has an outer diameter larger than a first outer diameter when mounting the porous structure onto the stent.
Owner:TERUMO KK

Resonant induction wireless power transmission converter with power factor correction

The invention discloses a resonance induction wireless power transmission converter with a power factor correction function, and belongs to the technical field of wireless power supply. According to the converter, a single-stage integrated framework is adopted, an interlaced power factor correction sub-stage and a resonant induction type wireless power transmission sub-stage are deeply fused, and an intermediate DC-DC conversion stage of a traditional multi-stage framework is omitted; the resonant induction WPT sublevel realizes non-contact energy transmission through the transmitting coil, the receiving coil and the mutual inductor, and power switch tubes of the full-bridge inverter all realize zero-voltage switching, so that the switching loss is reduced; and the output side provides stable direct current through the full-bridge rectification and filtering module. The device is compact in size, high in efficiency and suitable for medium-low-power wireless power supply scenes such as consumer electronics and biomedical implants.
Owner:NORTHEASTERN UNIV CHINA

Hybrid Magnetic-Ultrasonic Wireless Interrogation of Millimeter-Scale Biomedical Implants With Magnetoelectric Transducer

Embodiments can relate to an implant stimulation and recording system. The system can include a receiver. The system can include an interrogator having a transmitter coil and an ultrasound transducer. The system can include an implant having an integrated circuit and a magnetoelectric transducer. Low-frequency magnetic fields are generated by the transmitter coil and are converted into an electric voltage by the magnetoelectric transducer. Ultrasound energy is generated by the transducer and converted into an electric voltage by the magnetoelectric transducer. When voltage is applied to the magnetoelectric transducer, the magnetoelectric transducer generates magnetic fields and ultrasound waves, wherein the receiver detects the magnetic fields and ultrasound waves generated by the magnetoelectric transducer.
Owner:THE PENN STATE RES FOUND INC

Method for preparing spherical Ti-X alloy powder through powder metallurgy-atomization powder preparation

The invention discloses a method for preparing spherical Ti-X alloy powder by utilizing powder metallurgy-atomization powder preparation, which comprises the following steps: preparing a Ti-X alloy blank with uniform components through a powder metallurgy process, and carrying out atomization powder preparation by taking the blank as a raw material. According to the method, the problem of component uniformity is solved through powder metallurgy, the sphericity degree of the powder is guaranteed in combination with atomization powder preparation, repeated smelting is avoided, the production period is remarkably shortened, and the obtained powder is uniform in component and high in sphericity degree and meets the requirements of additive manufacturing or other fields; the material has wide application prospects in the fields of biomedical implants, nuclear reactor radiation shielding materials, aerospace high-temperature parts and the like.
Owner:XIAN UNIV OF TECH

Method for preparing polycaprolactone through rapid cooling crystallization

PendingCN121450074ACrystallinityQuenching
The invention provides a method for preparing polycaprolactone through rapid cooling crystallization, and belongs to the technical field of high polymer materials. The method comprises the following steps: preparing a nano nucleating agent containing an amide group through photopolymerization; performing high-shear mixing on the melt; quenching and curing; and performing two-stage infrared heat treatment. Through cooperation of high-shear pre-orientation and ultra-fast phase change, the semi-crystallization time is controlled within 1.5 min, through infrared heat treatment, the crystallinity reaches 85% or above, the defect that molecular chains in a low-temperature section of a traditional process cannot be arranged in order is overcome, and the method is suitable for the fields of biomedical implant materials, high-precision 3D printing, high-temperature packaging and the like and has remarkable industrial application value.
Owner:SHENZHEN ESUN IND

Ti6al4v surface diamond-doped micro-arc oxidation wear-resistant bioactive coating and preparation method thereof

The application is a kind of Ti6Al4V surface diamond doped micro-arc oxidation wear-resistant bioactive coating, which is composed of a ceramic layer mainly of TiO2 and randomly distributed nano-diamond particles formed after micro-arc oxidation on the surface of Ti6Al4V base material, and the Al and V contents in the coating are less than 1.0wt% and 0.1wt% respectively. The preparation method comprises the following steps: configuring sodium silicate, sodium phosphate or beta-glycerophosphorus sodium, sodium hydroxide into electrolyte, adding nano-diamond powder and anti-settling agent to make nano-diamond uniformly dispersed in the electrolyte, and then using micro-arc oxidation technology to prepare low Al and low V diamond doped micro-arc oxidation bioactive coating in the electrolyte. The application scheme is simple and easy to operate, the wear resistance of the coating can be improved by 2-5 times, in addition, the harmful elements Al and V in the coating are low, which is suitable for being used as biomedical implant materials.
Owner:TAIYUAN UNIVERSITY OF TECHNOLOGY

Polyvinylidene fluoride-trifluoroethylene film having nanorod array on surface and preparation thereof

The application discloses a polyvinylidene fluoride trifluoroethylene film with nanorod array on the surface and a preparation method thereof, and belongs to the field of biomedical materials. The preparation method comprises the following steps: preparing a polyvinylidene fluoride trifluoroethylene film by a solution casting method, and performing annealing crystallization treatment; stacking the polyvinylidene fluoride trifluoroethylene film on an anodic aluminum oxide template, heating and heat preservation on a hot plate, and naturally cooling along with the hot plate; then, dissolving the anodic aluminum oxide template by using a sodium hydroxide solution, cleaning multiple times by using deionized water and ethanol to remove residual sodium hydroxide, and drying; and performing polarization treatment. The preparation method is simple, and the cost is relatively low; the polyvinylidene fluoride trifluoroethylene film with nanorod array on the surface can be obtained, the polyvinylidene fluoride trifluoroethylene film has good piezoelectric performance, can provide electrical signal stimulation to cells or tissues, and has good biocompatibility, so that the polyvinylidene fluoride trifluoroethylene film can be used as a biomedical implant, and cell growth and tissue repair and regeneration can be promoted.
Owner:ZHEJIANG UNIV

Mechanical metamaterial cell with zero poisson's ratio properties

The application discloses a mechanical metamaterial cell with zero Poisson's ratio, and belongs to the technical field of mechanical metamaterials. The cell comprises symmetrically arranged upper and lower plates, upper and lower sets of horn pegs arranged at the four corners of the inner sides of the plates, an elastic body set connected by the upper and lower sets of horn pegs, and a set of flexible hinge components arranged at the midpoint positions of the four edges of the upper and lower plates. The pre-tension of the elastic body set keeps the set of flexible hinge components pre-bent inward. When the cell bears an axial load, the set of flexible hinge components produces coordinated inward bending deformation, so that the cell shrinks along the axial direction and keeps the lateral dimension stable, realizes the axial zero Poisson's ratio characteristic, and has energy absorption capacity. The cell has self-recovery capability and high cycle life based on elastic deformation, and is modular in design, convenient to assemble, disassemble and maintain, and suitable for application scenarios such as aerospace buffer devices, biomedical implants and precision instrument supporting structures.
Owner:CHANGCHUN UNIV OF TECH

Antibacterial alloy material for biomedical implants and instruments

An antibacterial alloy material suitable for making biomedical implants and surgical instruments and devices associated with biomedical implantation is disclosed. The alloy material comprises about 50–99.99 wt.% Ti, about 1–49 wt.% Cu, and about 0.01–10 wt.% SiO2. The antibacterial alloy material imparts antibacterial properties by enabling controlled ion release to inhibit biofilm formation, addressing issues like peri-implantitis associated with conventional bio-inert materials. In addition, the antibacterial alloy material enhances osseointegration and improves the mechanical durability of the resulting implants and surgical instruments and devices, including hardness and wear resistance. In addition, the antibacterial alloy material exhibits anti-corrosive properties and may be fabricated via techniques like spark plasma sintering (SPS).
Owner:TITAN64 INC

Bone implant as well as preparation method and application thereof

The invention discloses a bone implant as well as a preparation method and application thereof, and belongs to the technical field of biomedical implants and medical instruments. A hierarchical micro-nano composite structure is arranged on the surface of the bone implant and comprises a curved surface micron structure array regularly distributed on a titanium or titanium alloy substrate and a titanium dioxide nanotube array growing in situ on the surface of the curved surface micron structure array. According to the method, a femtosecond laser processing technology is adopted, according to a preset computer-aided design pattern, accurate ablation is carried out on the surface of a titanium or titanium alloy substrate, a periodic curved surface micron structure array is etched, and then anodic oxidation treatment is carried out; a layer of titanium dioxide nanotube array can be uniformly grown on the surface of the whole curved surface micron structure array in situ. The structure can regulate and control the expression of cell osteogenesis related genes through mechanical stimulation, and is expected to realize faster and stronger osseointegration in the implant implantation process of complicated patients with diabetes, osteoporosis and the like.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

A method for preparing photopolymer additive manufacturing ceramic biomimetic structural composite materials

This invention belongs to the field of additive manufacturing technology for ceramic biomimetic materials, and provides a method for preparing ceramic biomimetic structural composite materials by photopolymerization additive manufacturing. This method utilizes a layer-by-layer scanning strategy and parameterized control of the gaps and interlayer overlaps of the curing units to construct a three-dimensional interconnected porous structure with gradient, periodic, or biomimetic morphology during the forming stage. Optimized ultrasonic cleaning and staged precise degreasing processes ensure the integrity of the preform. The composite material is then achieved through melt infiltration, impregnation, or sol-gel processes. This invention solves the technical problems in existing photopolymerization manufacturing, such as the difficulty in accurately constructing biomimetic multi-level structures, uneven interfacial bonding of composite materials, and easy deformation of the preform during heat treatment. It is suitable for preparing high-performance composite materials such as bamboo-inspired gradient structures and shell-inspired periodic structures, and has significant application value in fields such as biomedical implants.
Owner:西安国宏天易智能科技有限公司

Self-adhesive silk fibroin-based soft tissue repair patch as well as preparation method and application thereof

The invention belongs to the technical field of biomedical implant materials, and particularly relates to a self-adhesive silk fibroin-based soft tissue repair patch as well as a preparation method and application thereof. The invention provides a self-adhesive silk fibroin-based soft tissue repair patch. The self-adhesive silk fibroin-based soft tissue repair patch comprises a substrate layer and an adhesive layer attached to the surface of one side of the substrate layer, the substrate layer is a silk fibroin woven mesh; the bonding layer comprises a viscous molecule, a polyphenol cross-linking agent and a moisturizing regulator, the viscous molecule is a modified molecule obtained by grafting a catechol group on a main chain of a natural high-molecular compound, and the polyphenol cross-linking agent and the viscous molecule form a cross-linked network. The self-adhesive silk fibroin-based soft tissue repair patch provided by the invention can be stored in a dry state, can be activated after being rehydrated, realizes wet self-adhesion through covalent binding, does not need suture fixation, simplifies surgical operation, can be suitable for various surgical scenes such as open and endoscopic surgery (or minimally invasive surgery) and has good clinical application value.
Owner:ZHEJIANG XINGYUE BIOTECH

Reduction sintering method of silicon nitride ceramic and application thereof

PendingCN121377788AImplantGrain boundary
The invention belongs to the field of ceramic materials, and discloses a reduction sintering method and application of silicon nitride ceramic. According to the method, a specific reducing agent is introduced into ceramic powder, surface oxygen is effectively removed, formation of a grain boundary glass phase is inhibited, and the sintering densification process is remarkably promoted through a gas phase transmission mechanism. The grain size of the prepared silicon nitride ceramic is less than or equal to 200 nm. The silicon nitride ceramic prepared by the invention has excellent mechanical properties and thermal properties: the density is greater than or equal to 98%, the bending strength is greater than or equal to 1000 MPa, the fracture toughness is greater than or equal to 9 MPa.m < 1 / 2 >, the hardness is greater than or equal to 1800 HV1.0, the residual oxide content is less than or equal to 3%, and the thermal conductivity is greater than or equal to 80 W / m.K. The material is suitable for the fields of aerospace engine parts, precision mechanical bearings, cutting tools, biomedical implants, electronic packaging heat management materials and the like.
Owner:YONGJIANG LAB

Electrolyte for surface micro-arc oxidation treatment of TC4 / Mg alloy three-dimensional interpenetrating composite material, application and composite material

An electrolyte for micro-arc oxidation treatment of TC4 / Mg alloy three-dimensional interpenetrating composite materials comprises the following components: a main film-forming agent of 18-22 g / L, a complexing agent of 3-5 g / L, an additive of 7-10 g / L, a pH adjuster of 4-6 g / L, a stabilizer of 5-7 mL / L, and the balance being deionized water; the pH of the electrolyte is 12-14. This invention is the first to discover that the concentration of EDTA-2Na has completely opposite regulatory effects on the roughness of the TC4 titanium alloy framework phase and the Mg alloy phase coating: increasing the concentration decreases the roughness of the TC4-PEO coating side and increases the roughness of the Mg-PEO coating side. This invention is the first to reveal the opposite regulatory laws of the roughness of the two phases, provides an optimal formulation for balancing the wear resistance of the two phases, and elucidates the synergistic wear mechanism, thereby achieving a balance in the wear resistance of the two phases of the three-dimensional interpenetrating composite material. The electrolyte of this invention, when used for surface micro-arc oxidation treatment, can improve the wear resistance of materials; therefore, the electrolyte of this invention can be used for surface modification of materials in aerospace, biomedical implants, and vehicle engineering fields.
Owner:AVIC TEST GOLD STONE TESTING TECH (WUXI) CO LTD