The invention relates to a fluoropolymer coating solution and a weather-resistant coating obtained therefrom. Fluoroplastics have excellent dielectric property and chemical corrosion resistance, high and low temperature resistance, and other excellent weatherability. At the same time, fluoroplastics also have the properties of waterproofness, no stickness, low friction coefficient, and good self-lubricating performance, etc. Currently, fluoroplastics are widely used in chemicals, electronics, electrical engineering, aviation, aerospace, semiconductors, machinery, textiles, construction, medicines, automobiles and other industrial fields. However, due to the intrinsic characteristics of fluoroplastics, the processing difficulty is very large. After long-term in-depth study, the inventor of the invention finds that the fluoropolymer coating solution provided in the invention can overcome the above disadvantages in the prior art. The coating obtained from the fluoropolymer coating solution provided in the invention has the characteristics of high fluorocarbon content, room temperature curing, good bonding strength with various substrates, no need of adhesive, convenient use and the like. The coating solution can be subjected to on-site construction under a variety of circumstances, and while improving the using performance, the use cost is reduced.