58results about How to "Inhibition" patented technology

This invention belongs to the field of pharmaceutical technology, specifically relating to the application of a small-molecule antioxidant in mitigating vascular damage in type 2 diabetes. To develop an effective solution for addressing vascular damage in diabetic patients, this invention, through research, discovered that Lithospermoside can specifically inhibit XO in the cell membrane anchoring state, effectively reducing ROS production in the thoracic aorta, thereby significantly reducing BUN, E-selectin, MDA, and UACR. Simultaneously, it inhibits the fluorescence intensity of nitrotyrosine staining, thus alleviating vascular endothelial damage in type 2 diabetes with persistent hyperglycemia. It exerts an antioxidant effect to slow down diabetic vascular damage and protect blood vessels, providing an effective material basis and new ideas for the prevention and treatment of vascular damage in type 2 diabetes.

This invention relates to a resin composition for injection molding, comprising a poly(3-hydroxyalkanoate) resin. The poly(3-hydroxyalkanoate) resin comprises at least one copolymer of 3-hydroxybutyrate units and other hydroxyalkanoate units. The average content of 3-hydroxybutyrate units in the poly(3-hydroxyalkanoate) resin is 92 mol% or more and 99 mol% or less. The poly(3-hydroxyalkanoate) resin, obtained by gel permeation chromatography using chloroform solvent, has a polystyrene-converted weight-average molecular weight of 210,000 or more and 380,000 or less, and the proportion of components with a weight molecular weight of 200,000 or less in the weight molecular weight distribution is 35 wt% or more and 60 wt% or less.

This invention discloses a Litsea cubeba extract, its preparation method, and its applications, relating to the field of pharmaceutical compound technology. The Litsea cubeba extract has the structural formula shown in Formula I: (Formula I). ​​This Litsea cubeba extract is isolated from the Litsea cubeba plant. This novel compound can significantly inhibit NO production in an LPS-induced RAW264.7 cell inflammation model; alleviate the immune-inflammatory response in an in vitro 3D skin model of atopic dermatitis; inhibit epidermal thickening and repair skin barrier function; and reduce the inflammatory response by inhibiting the PI3K / Akt signaling pathway. It has clinical application potential in the treatment of atopic dermatitis and can be used to prepare anti-atopic dermatitis drugs, showing promising application prospects.

The application provides a gradient temperature difference processing method for preventing and controlling rancidity and deterioration of rice bran decoction pieces, comprising the following steps: sequentially subjecting newly harvested rice bran to low-temperature rapid cooling, medium-temperature roasting, high-temperature roasting and second ultra-low-temperature rapid cooling after removing impurities by primary screening, so as to prevent and control rancidity and deterioration of rice bran decoction pieces. The application utilizes rapid and strong temperature difference change to prevent and control the reaction after grinding contact oxidation, destroys the autoxidation system of rice bran, effectively prevents and controls the generation of oxidized toxic substances and the breeding and pollution of harmful microorganisms, and ensures the safety and effectiveness of medication.

A compressor drive device includes an inverter device including an inverter circuit that converts direct current into alternating current and a control portion, and a compressor including a motor connected to the inverter circuit and a piston that reciprocates in a cylinder under the action of the motor. The control portion includes a multi-phase PWM signal generation portion that can set a plurality of carrier frequencies for driving the compressor, and a bottom dead center detection portion that detects a bottom dead center of the piston in the compressor. In a case where the carrier frequency is switched from a high frequency to a low frequency during rotation of the compressor, the timing of the switching is made to be the bottom dead center of the compressor. Thus, generation of overcurrent can be well suppressed when the carrier frequency is switched.

This application relates to a high-nickel cathode material and its preparation method, and a lithium-ion battery. The chemical formula of the high-nickel cathode material is Li. σ Ni a Co b Mn c M1 x M2 y M3 z O 2+α Wherein, 0.80<σ<1.20, a+b+c+x+y+z=1, 0.7<a<1.0, 0<b<0.05, 0<c<0.3, 0<x<0.3, 0<y<0.3, 0<z<0.3, 0<α<0.1, M1, M2, and M3 are each independently including at least one of Al, Co, Zr, Ti, Mg, Y, La, Sr, Ba, W, Mo, Nb, and Si, and M1, M2, and M3 are all different; the high-nickel cathode material includes a high-nickel material matrix and a coating layer. Cu-Kα rays are used to perform XRD measurements on the high-nickel material matrix and the high-nickel cathode material, respectively. The intensity of the (104) diffraction peak appearing in the diffraction angle range of 44-45° is recorded as I. b (High-nickel material matrix) and I c (High-nickel cathode material), the unit of diffraction peak intensity is counts, let the diffraction peak intensity difference P = I c -I b 0 < P < 1000. The high-nickel cathode material provided in this application has better high-temperature cycling performance and a low DC internal resistance growth rate.

This invention proposes an adaptive virtual impedance droop control method, system, device, and medium, relating to the field of droop control. The method includes: calculating the standardized reactive power of each local node and neighboring node based on the equivalent output impedance and reactive power droop coefficient; generating a correction amount for the virtual impedance based on the accelerated consensus algorithm and the standardized reactive power of each local node and neighboring node; adjusting the virtual impedance in the distributed grid topology according to the correction amount of the virtual impedance to obtain the adjusted dynamic virtual impedance; calculating the virtual impedance voltage drop based on the adjusted dynamic virtual impedance; calculating the feedforward compensation voltage reference value; calculating the common compensation amount of the preset virtual leader node and the local compensation amount of each local node and neighboring node to obtain the total voltage compensation command; adjusting the feedforward compensation voltage reference value according to the total voltage compensation command to obtain a voltage stabilization scheme, using the dynamic virtual impedance as the power distribution scheme.

The application discloses a carbon deposition resistant nickel-based catalyst for a dry reforming reaction of methane and a preparation method of the catalyst, and the preparation method comprises the following steps: step one, mixing lanthanum nitrate hexahydrate, aluminum nitrate nonahydrate and glycine, and adding deionized water, and stirring until a transparent solution is formed; step two, evaporating the transparent solution to form a gel; step three, drying the gel, igniting, and calcining to obtain a fluffy powder; grinding the powder to obtain a modified alumina carrier; step four, loading nickel on the modified alumina carrier by taking nickel nitrate hexahydrate as a precursor, so as to obtain the carbon deposition resistant nickel-based catalyst for the dry reforming reaction of methane.

The present invention aims at achieving labor saving, and achieving low cost of introduction and suppression of the preparation of the moving path, thereby reducing the introduction barrier of the collaborative robot accompanying the movement. The robot system has a robot (10) and a control device (20), the robot (10) has a free dolly (12) and a mechanical arm (11) placed on the free dolly (12), and the control device (20) controls the mechanical arm (11). The control device (20) controls the mechanical arm (11) in order to perform a predetermined task, and controls the mechanical arm (11) in order to move the robot (10) itself.

The invention discloses a sex attractant for yellow rice borers as well as a preparation method and application of the sex attractant, and relates to the technical field of agricultural pest monitoring, prevention and control. The sex attractant comprises an active component which is prepared from (Z)-dodecyl-9-ene-1-yl acetate, (E)-dodecyl-9, 11-diene-1-yl acetate and (7E, 9Z)-dodecyl-7, 9-diene-1-yl acetate, and the sex attractant is prepared from an active component which is prepared from the following components of (Z)-dodecyl-9-ene-1-yl acetate, (E)-dodecyl-9, 11-diene-1-yl acetate and (7E, 9Z)- According to the sex attractant disclosed by the invention, aiming at the current sugarcane area dominant population, the three active components have a synergistic effect, so that the trapping activity of the current sugarcane area dominant population is remarkably improved, and the problems that the trapping activity is low and the specificity is poor due to the fact that a control object is not matched with the dominant population in the existing sex attractant product are solved. Field trials show that the trapping quantity of the sex attractant provided by the invention on the yellow rice borers is obviously higher than that of a control group, the sex attractant has extremely high population specificity, and accurate monitoring and efficient trapping and killing of yellow rice borer populations can be realized.

This utility model relates to the field of relay technology, and provides an anti-arc safety relay for charging piles, including a relay housing and a coil installed at the center of the bottom of the housing; an iron core, which is slidably inserted into a through hole running vertically through the center of the coil; a transmission column, which is installed at the top of the iron core; a moving contact assembly, which is installed at the top of the transmission column; and two arc-extinguishing components, which are symmetrically installed on the left and right side walls near the top of the relay housing. This anti-arc safety relay for charging piles, through the scientific layout of multi-layer arc-extinguishing grids, a fast-rebound disconnection mechanism, and a buffer reset design, can effectively suppress and quickly eliminate the arc generated between the moving and stationary contacts, significantly improving the safety performance and service life of the relay.

This invention relates to a method for seamless welding of multi-cavity profiles and integrated molding of sound insulation layers, as well as a door and window frame. It belongs to the field of building door and window profile processing and manufacturing technology. By moving the injection of the sound insulation composite material before welding, pre-injection is completed when the profile cavity ports are open, solving the problem of material not flowing into the closed corner area and resulting in missing corner sound insulation filling in existing post-injection processes. By applying a heat-activated protective film to the welding end face and implementing a staged heating and pressurization process, the flow homogenization conditions of the molten material on the outer surface are improved, effectively reducing the width of the white weld seam at the corner. By selecting a sound insulation material system with a final curing temperature matching the welding residual heat temperature range, the residual heat during the natural cooling process of the corner after welding drives the final curing of the material, merging the welding process and the sound insulation layer molding process. No structural modifications to existing welding equipment are required, making it easy to promote and apply under existing production conditions.

This invention relates to the field of biopharmaceutical technology, specifically to... SARM1 The application of related reagents in the preparation of products for the diagnosis and / or treatment of hemophagocytic lymphohistiocytosis-like liver injury. The results of this invention demonstrate... SARM1 It is both a circulating biomarker in HLH and an intrinsic regulator of iNKT cell fate. SARM1 By stabilizing LCK and maintaining TCR signaling, excessive iNKT1 bias and IFN-γ-driven liver injury can be prevented. These findings highlight... SARM1 Its important value as a potential diagnostic biomarker and therapeutic target for HLH in children provides a new strategy for the treatment of hemophagocytic lymphohistiocytosis-like liver injury in children.

This invention proposes a culture medium and cultivation method for Tremella fuciformis, belonging to the field of Tremella fuciformis cultivation technology. It is prepared from the following raw materials in parts by weight: 0.5-1 parts antibacterial agent, 5-7 parts traditional Chinese medicine residue, 3-5 parts sugarcane bagasse, 2-3 parts fermentation extract, 30-40 parts cottonseed hulls, 7-10 parts wheat bran, 0.5-1 part gypsum, and 50-60 parts sterile water. The Tremella fuciformis culture medium obtained by this invention can significantly inhibit the growth of pathogenic bacteria during cultivation, reduce the pathogenicity rate, and increase the yield of Tremella fuciformis. Simultaneously, it increases the content and efficacy of active substances in Tremella fuciformis, producing selenium-enriched Tremella fuciformis polysaccharide. The active substances exhibit excellent antioxidant, anti-inflammatory, anti-tumor, moisturizing, hypoglycemic, hypolipidemic, and cardiovascular protective effects. Using this invention's culture medium, along with a suitable ratio of Tremella fuciformis and Clematis chinensis symbiotically, provides a new method and material for Tremella fuciformis cultivation, resulting in Tremella fuciformis with better utilization value and broad application prospects.

The application provides application of tanshinone or a derivative thereof in preparation of a monkeypox virus resisting drug. In a cell model infected by the monkeypox virus, production of infectious virus particles can be significantly reduced. In a mouse infection model, Tanshinone VII can effectively reduce pathological damage of lung tissues and improve survival rate of animals. The above evidence indicates that Tanshinone VII has potential efficacy in resisting the monkeypox virus. It is inferred that tanshinone or the derivative thereof can play a double role in resisting the monkeypox virus and host protection.

This invention discloses a layered concrete structure with anti-penetration and filtering properties and its preparation method. It solves the problem in existing technologies where only the composition of the concrete layers is changed without improving the overall filtering performance. This invention has the beneficial effects of improving filtering performance and preventing further crack development. The specific solution is as follows: A layered concrete structure with anti-penetration and filtering properties includes a fiber-reinforced concrete layer and an intermediate composite material layer. The intermediate composite material layer is placed between two fiber-reinforced concrete layers. The fiber-reinforced concrete layer and the intermediate composite material layer are periodically arranged to form a layered concrete structure to enhance the filtering performance and improve the anti-penetration performance. The fiber-reinforced concrete layer contains steel fiber reinforcement to enhance the anti-penetration performance of the layered concrete structure. The wave transmittance in the intermediate composite material layer is different from that in the fiber-reinforced concrete layer, and the intermediate composite material layer is bonded to the fiber-reinforced concrete layer.

This utility model discloses a low-noise water heater, comprising: a heating element disposed at the bottom of a cavity; the heating element includes a heating tube and a heat spreader plate, the heating tube and the heat spreader plate being thermally connected, the heat spreader plate being attached to the bottom of the cavity, and the heating tube being spirally arranged; the ratio of the thickness of the heat spreader plate to the surface load of the heating tube is greater than or equal to 40%, and the thickness of the heat spreader plate is 3.5-5mm; wherein, the effective heat transfer area ratio of the heating tube and the heat spreader plate is greater than or equal to 50%, and the heating tube and the heat spreader plate cooperate to homogenize the heat generated by the heating tube; a first through hole is provided on the lower surface of the cavity, and a water inlet pipe passes through the spiral gap of the heating tube and the first through hole in sequence; a bracket is provided on the inner surface of the cavity, the bracket being disposed on the first through hole, and the bracket being used to buffer the water flow of the water inlet pipe. This device fundamentally solves the noise problem caused by uneven heating and bubble bursting during the heating process.

This invention discloses a method for optimizing airflow organization to prevent condensation in a converter cabinet, comprising: arranging miniature infrared thermal imaging and high-frequency humidity sensors inside the cabinet to periodically collect data and generate a thermo-humidity coupled cloud map; identifying local airflow stagnation areas in real time based on the cloud map; adjusting the morphology of the biomimetic adaptive airflow guiding structure to directionally guide airflow to the stagnation area; employing ultrasonic atomization-electrostatic adsorption synergistic dehumidification to treat humid air, and utilizing the self-heating of surrounding components and a phase change heat storage layer to maintain the area temperature above the dew point; constructing a digital twin model to predict potential stagnation areas and generating a pre-control scheme to adjust the airflow guiding structure, phase change layer, and dehumidification parameters in advance; detecting the condensation amount on the surface of easily condensing components, and blowing away droplets through local airflow nozzles when a threshold is reached. This invention can accurately identify and eliminate airflow stagnation, effectively suppress condensation formation, avoid insulation degradation and circuit short circuits, and improve the operational stability and component life of the converter cabinet in high humidity environments.

The utility model discloses a kind of defoaming devices, it is related to laundry detergent production technical field.When laundry detergent is stirred, the fluctuation amplitude of laundry detergent liquid level is larger, leading to the increase of liquid phase air entrainment, thereby intensifying foam generation, so that the efficiency of device defoaming is reduced, thereby affecting the use effect of device.The utility model includes device main body and processing mechanism, processing mechanism is arranged inside device main body, processing mechanism includes the threaded rod of being set at the top end inside device main body.This utility model is provided with device main body, processing mechanism, threaded rod and buoyancy plate, threaded rod can be rotated by rotating driving handle, so that fixed seat can be driven to move up and down, buoyancy plate can be conveniently floated on the surface of laundry detergent, when buoyancy plate contacts liquid surface, physical barrier layer is formed using liquid surface tension, effectively suppress the foam generated due to liquid violent disturbance in stirring process, improve the practicability of device.

The present application relates to a kind of bubble drinks for high uric acid population, production method, equipment, belong to functional food processing technical field.It includes the following weight parts of component: acid-eliminating composition extract: 6 to 9 parts by crude drug amount;Alkalization acid-eliminating regulator: 0.9 to 1.5 parts;Natural sweet and functional agent: 0.5 to 6 parts;And the balance of water;Acid-eliminating composition extract is prepared from chicory, tuckahoe and gardenia;Alkalization acid-eliminating regulator is composed of food-grade sodium bicarbonate and citric acid, both are reacted in water to generate sodium citrate buffer pair, and the mass ratio of citric acid and sodium bicarbonate is 1:(1.2-2.0), and the final pH of the bubble drink is 6.2-6.8.Utilize the sodium citrate buffer generated by alkalization acid-eliminating regulator reaction, fundamentally resolve uric acid crystallization, prevent uric acid kidney stone.Combined with acid-eliminating composition extract, physiological level of synthesis inhibition and excretion promotion and physicochemical level of urine alkalization and solubility promotion are realized.

The utility model relates to a kind of recycled aggregate durable pavement structure, it includes: stratiform main body, the stratiform main body sequentially includes from bottom to top: recycled aggregate particle compaction layer, mortar concrete pouring lower layer, mortar concrete pouring upper layer and inorganic cementing material reinforcing layer;The thickness of the recycled aggregate particle layer is 2~4cm, recycled aggregate particle is obtained by waste tyre;The thickness of the mortar concrete pouring lower layer is 8~12cm, the thickness of the mortar concrete pouring upper layer is 7~8cm;The thickness of the inorganic cementing material reinforcing layer is 5~10cm.

This invention discloses a method for controlling corner cracks in continuously cast slabs of low-manganese peritectic steel, belonging to the field of continuous casting production technology in iron and steel metallurgy. This method targets low-manganese peritectic steel with a carbon content of 0.12%-0.16% and a manganese content of 0.35%-0.9%. It solves the problem of corner cracks in continuously cast slabs of low-manganese peritectic steel by employing a combination of dual control of primary cooling water, control of the liquid level in the crystallizer, selection and use of protective slag, zoned control of the specific water volume in the secondary cooling water, dual acceptance of the crystallizer's perpendicularity, and synergistic adjustment of the straight guide section and the fan-shaped section. This invention eliminates the need for subsequent slab re-grinding, enabling hot slab delivery, reducing production costs, and improving production efficiency.

This invention discloses a method for purifying reducing agent coal used in industrial silicon production, belonging to the field of chemical raw material purification technology. The invention provides a purifying agent that enters the interior of the reducing agent coal through the pores to carry out an iron removal reaction. Nonylphenol polyoxyethylene ether promotes the dissolution of oxalic acid in water and inhibits foam formation. Iron in reducing agent coal used in industrial silicon production mainly exists in two modes: Fe2O3 accounts for 40%-50%, and FeS accounts for 50%-60%. Since Fe2O3 can react with oxalic acid (H2C2O4) to form a precipitate that is insoluble in water, washing with water after soaking achieves the purpose of iron removal. The method of purifying reducing agent coal used in industrial silicon production using a purifying agent can significantly remove trace impurities such as Fe, Al, and Ca that affect the quality of industrial silicon products.

This invention proposes an electropolymerized polymer electrolyte, its preparation method, and a lithium battery. The preparation method includes the following steps: S1, mixing an alkali metal salt, an electrolyte solvent, a positive electrode additive, and a polymer monomer to obtain an electrolyte precursor; S2, injecting the electrolyte precursor between the positive and negative electrodes to assemble a battery; S3, subjecting the battery to a pre-cycling process of "constant current charging-constant voltage charging-constant current discharging" to obtain the polymer electrolyte; wherein the polymer monomer includes electropolymerizable cyclosiloxane compounds, and the constant voltage charging voltage is 4.5~4.7V. This invention utilizes electropolymerizable cyclosiloxane compounds to undergo ring-opening polymerization at high voltage, synergistically with positive electrode additives such as lithium difluorooxalate borate, to achieve in-situ construction of a dense and stable polymer electrolyte layer at the high-voltage positive electrode interface. This significantly suppresses solvent oxidation and electrode side reactions, improving the battery's excellent cycle stability and safety even at high voltages.

This invention discloses a sulfur-containing 5-aminosalicylic acid prodrug and its uses, belonging to the field of biomedical technology. The sulfur-containing 5-aminosalicylic acid prodrug of this invention has the structure shown in general formula I. This type of compound has good intervention effects on inflammation-related diseases, exhibiting more ideal anti-inflammatory activity than 5-ASA and sulfasalazine. It can also inhibit the production of hypochlorous acid and related inflammatory mediators by inhibiting myeloperoxidase (MPO), and can be used to prepare drugs for the prevention and / or treatment of inflammatory bowel disease, and drugs for the prevention and / or treatment of diseases related to abnormal oxidative stress.

The application discloses a composite nanofiber membrane, a modified nanofiber membrane and application thereof, and relates to the technical field of nanofiber membranes.The composite nanofiber membrane comprises a first electrolyte layer, a modified nanofiber membrane and a second electrolyte layer arranged in sequence.The first electrolyte layer comprises iron phthalocyanine, a first polymer and a first electrolyte lithium salt, and the second electrolyte layer comprises a second polymer and a second electrolyte lithium salt.The modified nanofiber membrane comprises modified nanofibers and a three-dimensional porous structure grown in situ on the modified nanofibers.The modified nanofibers contain ferrous iron, and the material of the three-dimensional porous structure contains iron phthalocyanine.The composite nanofiber membrane greatly improves the content of the electrolyte amorphous region, improves the dissociation of the electrolyte lithium salt, promotes the increase of ionic conductivity and ionic transference number, reduces the generation of side reactions, and is beneficial to realizing stable and long-acting interface performance.

This invention belongs to the field of polymer composite materials technology, and provides a low-odor flame-retardant polypropylene composite material and its preparation method. The preparation of this composite material includes the following steps: mixing polypropylene, a flame retardant, a lubricant, an antioxidant, and a defoamer to obtain a premix; mixing the premix and an odor inhibitor to obtain an intermediate product; and melt-extruding and granulating the intermediate product to obtain the low-odor flame-retardant polypropylene composite material. This invention eliminates odorous volatile substances generated during the preparation of the premix by heating, defoaming with a defoamer, and vacuuming. Furthermore, after eliminating the odorous volatile substances, an odor inhibitor is added to further suppress the generation of unpleasant odors. The resulting polypropylene composite material has advantages such as low odor and high flame retardancy.

This invention relates to a pretreated reinforced recycled aggregate concrete and its preparation method, comprising the following raw materials: 320-360 parts cement; 20-40 parts fly ash; 80-120 parts mineral powder; 585-670 parts manufactured sand; 1050-1200 parts recycled coarse aggregate; 156-172 parts water; and 11-12.3 parts admixtures. After pretreatment, the concrete prepared from the recycled coarse aggregate exhibits significantly improved performance compared to the untreated recycled coarse aggregate. The synergistic effect of multiple pretreatment methods significantly improves the water absorption, crushing index, and apparent density of the raw coarse aggregate. Pretreatment of the recycled coarse aggregate provides enhanced conditions for internal hydration in the recycled concrete and simultaneously improves the surface roughness of the recycled coarse aggregate, thus enhancing the workability and increasing the strength of the concrete.