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499results about How to "Inhibition" patented technology

Scalp care composition and application thereof

The invention relates to the technical field of daily chemical products, in particular to a scalp care composition and application thereof. From the perspective of scalp care, selenium disulfide and piroctone olamine salt are taken as bactericides and compounded with bactericidal and anti-dandruff components to form the organic and integrated anti-dandruff and scalp conditioning composition, and the composition has the effects of removing dandruff, relieving itching, soothing and controlling oil and can effectively relieve the problems of dry dandruff and fungal dandruff. The scalp care composition is added into the shampoo, serves as a main component of the multi-effect repairing and dandruff removing shampoo, can effectively solve the problems of oily dandruff, dry dandruff, scalp itching, scalp hair greasy, scalp sub-health and the like, and has the effects of reducing scalp inflammatory response, promoting updating of scalp cutin, inhibiting generation of scalp redundant sebum and the like; the nursing dimension is more comprehensive, and the application range is wider.
Owner:MENTHOLATUM (CHINA) PHARM CO LTD

Ultraviolet light catalysis assisted gallium nitride wafer polishing method

The invention belongs to the technical field of semiconductor manufacturing, and particularly relates to an ultraviolet light catalysis assisted gallium nitride wafer polishing method which comprises the following steps: S1, fixing a ground and flushed gallium nitride wafer on a clamp of a polishing machine; s2, the sealed cabin of the polishing machine is vacuumized until the vacuum degree reaches a set vacuum degree threshold value, and then the sealed cabin is filled with oxygen until the pressure value of the oxygen in the sealed cabin reaches a set pressure threshold value; s3, an ultraviolet lamp and a heater are turned on, the ultraviolet lamp irradiates the polishing solution, the heater heats the polishing solution to a set temperature and keeps the temperature constant, and then the polishing machine is started to polish the gallium nitride wafer; and S4, cleaning the polished gallium nitride wafer. According to the method, the oxidation rate is increased, and the polishing efficiency of the gallium nitride wafer is further improved.
Owner:SHANDONG JINGGALLIUM SEMICON CO LTD +1

Porous carbon material, silicon-carbon composite material and application thereof

The invention relates to the technical field of batteries, in particular to a porous carbon material, a silicon-carbon composite material and application of the porous carbon material and the silicon-carbon composite material. According to the porous carbon material, the micropore rate phi, the pore volume Pv and the compressive strength Cs meet the relational expression that (Cs * phi) / Pv is larger than or equal to 550 and smaller than or equal to 1050, and the micropore rate phi gt; and the compressive strength Cs is 600 to 850 MPa. The porous carbon material provided by the invention has high microporosity, and the microporosity phi, the pore volume Pv and the compressive strength Cs of the porous carbon material meet the relation that (Cs.phi) / Pv is more than or equal to 550 and less than or equal to 1050, so that the particle size of silicon particles can be effectively reduced, the absolute expansion of silicon in a carbon matrix is reduced, and the first effect and the cycling stability of the silicon-carbon composite material are improved.
Owner:JIANGXI ZICHEN TECH CO LTD

Ferromanganese phosphate precursor with high compaction density and preparation method thereof

The invention discloses a high-compaction-density ferromanganese phosphate precursor and a preparation method thereof, and belongs to the technical field of lithium batteries, and the provided preparation method comprises the following steps: step 1, respectively dissolving a manganese source, an iron source and a phosphorus source in water to form solutions; 2, adding a complexing agent into the iron source solution to form a complexing iron salt solution; step 3, mixing the complexing ferric salt solution, the manganese source solution and the phosphorus source solution, adding an oxidizing agent and alkali liquor, keeping the pH value of the system to be 5.5-8, heating and stirring for reaction, and synchronously introducing oxygen for bubbling during reaction; and 4, after the reaction is finished, carrying out solid-liquid separation, and drying and roasting to obtain the ferromanganese phosphate precursor. According to the method, under the action of the complexing agent, the homogeneity of iron-manganese coprecipitation is improved, oxygen is introduced for bubbling in the reaction process, and excessive growth of crystals is inhibited while the oxidation condition is ensured, so that the ferromanganese phosphate precursor is proper in particle size and uniform in distribution, and the positive electrode material prepared from the precursor has high compaction density and excellent electrochemical performance.
Owner:HUNAN YUNENG NEW ENERGY BATTERY MATERIALS CO LTD

Application of bacteriophage in reduction of cholera propagation

According to the application of the bacteriophage to reduction of cholera transmission, the bacteriophage phi YSZKA is preserved in the China Center for Type Culture Collection on August 1, 2018, the preservation number is CCTCC NO: M 2018513, and the bacteriophage phi YSZKA is classified and named as klebsiella pneumoniae bacteriophage phi YSZKA. The method solves the problems of secondary pollution, wide transmission of vibrio cholerae and the like of the traditional split bacteriophage. The application of the bacteriophage can reduce the toxin production efficiency of vibrio cholerae in oceans, soil and sewers, thereby providing more possibilities for prevention and control of cholera epidemic situation and alleviation of cholera symptoms.
Owner:NANJING AGRICULTURAL UNIVERSITY

Application of GATA3 inhibitor and PD1 inhibitor in preparation of medicine for treating breast cancer

The invention relates to application of a GATA3 inhibitor and a PD1 inhibitor in preparation of a medicine for treating breast cancer, and belongs to the technical field of biological medicine. The invention discloses application of a GATA3 inhibitor and a PD1 inhibitor in preparation of a medicine for treating breast cancer. The GATA3 regulates the transcription regulation of IFNbeta by inhibiting the enhancer activity of IFNB1, down-regulates an I-type interferon signal channel, inhibits the secretion of an MHC-I antigen presentation channel and a chemotactic factor CCL5 of breast cancer cells, reduces immune recognition, and achieves the purpose of immune escape. The immunotherapy for inhibiting GATA3 combined with the PD1 inhibitor to treat breast cancer effectively treats breast cancer mice, improves the IFN beta level in the mice, promotes the MHC-I antigen presentation pathway of the mice, improves the CCL5 level in the mice, and improves the CD8 + T cell level in a tumor immune microenvironment, thereby reducing tumor occurrence and inhibiting tumor growth.
Owner:THE SEVENTH AFFILIATED HOSPITAL SUN YAT SEN UNIV SHENZHEN

Additive for non-aqueous electrolyte solution, non-aqueous electrolyte solution, and electricity storage device

Disclosed is an additive for a non-aqueous electrolyte solution, which contains a cyclic sulfone compound represented by formula (1). X1 represents a sulfonyl group or a carbonyl group, and Z represents a monovalent group represented by formula (21), (22), (23) or (24). # imgabs0 #
Owner:SUMITOMO SEIKA CHEM CO LTD

Laser cutting device and cutting method thereof

The invention relates to the technical field of laser cutting, in particular to a laser cutting device and a cutting method thereof.The laser cutting device comprises multiple supporting legs, a cutting mechanism is installed at the tops of the multiple supporting legs, the cutting mechanism comprises a conveying frame, and the conveying frame is fixedly installed at the tops of the supporting legs; the number of the conveying frames is two, a first motor is fixedly installed on the side portion of the right conveying frame, the conveying rollers are rotatably installed in the conveying frames, the number of the conveying rollers is two, an output shaft of the first motor is fixedly connected with the rear conveying roller, and a conveying belt is installed on the surfaces of the conveying rollers. Through the arrangement of the cleaning mechanism, the surface of a material needing to be subjected to laser cutting can be subjected to water spraying cleaning, after impurities such as oil stains, dust and an oxide layer on the surface of the material are cleaned, a laser beam can accurately act on the pure surface of the material, and extra impurities cannot be generated on the cleaned surface of the material in the laser cutting process.
Owner:GUANGDONG RUIHUI INTELLIGENT TECH CO LTD

Application of breast milk oligosaccharide in regulating brain immunity

The invention belongs to the technical field of food, and relates to application of breast milk oligosaccharide in regulating brain immunity. Specifically, the invention relates to the non-therapeutic purpose of adjusting brain immunity by adjusting polarization of microglial cells M1 / M2, and the breast milk oligosaccharide is any one of 3-fucosyllactose, lactose-N-tetraose, lactose-N-neotetraose, 3 '-sialic acid lactose and 6'-sialic acid lactose. Research results show that a specific variety of breast milk oligosaccharides (especially 3-FL) can obviously inhibit the generation of neurotoxic factors NO, inflammatory factors TNF-alpha and IL-1beta in microglial cells, and promote the generation of anti-inflammatory cytokines IL-10 in the microglial cells, so that the state of the microglial cells is improved, damage repair is promoted, and the microglial cells are prevented from being damaged. Therefore, the effect of regulating brain immunity is achieved.
Owner:HEILONGJIANG FEIHE DAIRY CO LTD +1

High-safety flame-retardant lithium ion battery electrolyte with low-reactivity coordination structure

The invention provides a high-safety flame-retardant lithium ion battery electrolyte with a low-reactivity coordination structure, and relates to the technical field of energy storage batteries. High-stability bis (fluorosulfonyl) imide lithium salt is used as lithium salt, an ether solvent with weak solvation ability is used as an auxiliary solvent, and an additive is added. The low-reaction-activity solvent and the high-stability salt are adopted to replace high-reaction-activity components in a traditional electrolyte, the proportion of the lithium salt, the solvent and the additive is regulated and controlled to construct the high-safety flame-retardant lithium ion battery electrolyte with a low-reaction-activity coordination structure, and the thermal safety of the battery can be remarkably improved. According to the electrolyte, the self-heat-production reaction rate of an electrolyte-electrode interface and the generation of combustible gas are effectively inhibited, the thermal failure starting temperature and the triggering temperature of the battery are increased, the maximum temperature of thermal runaway is reduced, the intrinsic thermal safety of the high-energy-density lithium ion battery is greatly improved, and the electrolyte is suitable for the high-specific-energy lithium ion battery.
Owner:UNIV OF SCI & TECH BEIJING +1

Weather-resistant and aging-resistant polyethylene pipe and preparation method thereof

The present invention relates to a weather-resistant and anti-aging polyethylene pipeline and a preparation method thereof, and belongs to the technical field of polymer materials. The pipeline adopts high-density polyethylene resin, linear low-density polyethylene resin, polyimide resin powder, nano silicon dioxide, nano hexagonal boron nitride, polybenzimidazole fiber, carnosic acid, zinc glycyrrhetinate, antioxidant 1010, hindered amine light stabilizer, polydimethylsiloxane titanate cross-linked polymer, 3-methacryloxypropyl triethoxysilane as raw materials; wherein, polyimide resin powder, carnosic acid and zinc glycyrrhetinate are uniformly mixed, and then modified at 300°C to 350°C for 30min to 60min to obtain a modified product, which can better improve the weather resistance and aging resistance of the pipeline. Each component is compatible with each other, and a special modified preparation method is adopted to better play the synergistic effect of the components, and greatly improve the weather resistance and aging resistance of the polyethylene pipeline.
Owner:TIANJIN MANHUA PIPE MATERIAL IND CO LTD

Diffraction optical waveguide, preparation method thereof and head-mounted display equipment

The invention discloses a diffractive optical waveguide and a preparation method thereof, and a head-mounted display device, and relates to the technical field of augmented reality, and the preparation method of the diffractive optical waveguide comprises the steps: obtaining a target eye box range adaptive to a target crowd; according to the human eye parameters of each user group in the target group, splitting the target eye box range to obtain sub-eye box ranges adapted to each user group; diffractive optical waveguides adapted to the user groups are prepared based on the sub-eye box ranges, and the area of a coupled-out grating in each diffractive optical waveguide is smaller than the area of a coupled-out grating of an optical waveguide designed for covering the target eye box range. The optical efficiency and uniformity of the diffractive optical waveguide can be ensured, and the diffractive optical waveguide is prevented from generating obvious rainbow lines, so that the use experience of a user is improved.
Owner:GORE AOLAI OPTICAL TECHNOLOGY (SHANGHAI) CO LTD

Oroxylum indicum extract serving as skin oil control active matter as well as preparation method and application of oroxylum indicum extract

The invention relates to an oroxylum indicum extract serving as a skin oil control active matter as well as a preparation method and application of the oroxylum indicum extract. Wherein the oroxylum indicum extract serving as the skin oil control active matter at least comprises the following components in percentage by mass: 25%-35% of oroxylum indicum A and 20%-35% of oroxylum indicum B. The oroxylum indicum extract serving as the skin oil control active matter is natural and mild, can effectively inhibit skin oil secretion, can inhibit inflammation and can reduce lipid peroxidation products, so that the prepared cosmetics have excellent oil control and soothing effects, and are safe, green, natural and mild.
Owner:PROYA COSMETICS CO LTD

Acne removing essence and preparation method thereof

The invention discloses an acne-removing essence and a preparation method thereof, and particularly relates to the technical field of skin care products, the acne-removing essence comprises the following components by mass: 0.5-5% of salicylic acid; 1%-5% of tartaric acid; 2%-6% of nicotinamide; 0.5%-2% of colloidal sulfur; 1.5%-3% of tea tree essential oil; 1%-2% of hyaluronic acid; 0.5%-1% of ceramide; 1%-3% of glycerol; 1%-2% of trehalose; the salicylic acid is used for penetrating into skin, helping to relieve dead skin cells, reducing inflammation and accelerating skin renewal; the tartaric acid is used for realizing a stripping effect, can remove aged cuticles on the surface of the skin and promote the generation of new cells, so that the problem of acnes is helped to be improved. The acne-removing essence prepared by the invention has a relatively good moisturizing effect, so that skin barrier can be well maintained, keratin metabolism is promoted, grease secretion is inhibited, acne is effectively prevented, inflammatory response of the acne is relieved, and the actual use effect of the acne-removing essence is relatively good.
Owner:GUANGZHOU YOUYANG COSMETICS CO LTD

Composition with function of stabilizing skin enzyme activity as well as preparation method and application of composition

The invention provides a composition with a function of stabilizing skin enzyme activity as well as a preparation method and application of the composition, and the composition is prepared from the following components in parts by mass: 0.001 to 0.01 part of superoxide dismutase, 0.001 to 0.05 part of nicotinamide adenine dinucleotide, 0.11 to 12 parts of a polypeptide compound a and 0.005 to 0.5 part of a polypeptide compound b. The invention also provides a preparation method of the composition and application of the composition in preparation of skin care products for improving skin enzyme activity, repairing skin and resisting aging. The composition can be prepared into emulsion, solution, paste, gel or spray. The composition can effectively improve the enzyme activity of skin, improve the texture and appearance of the skin and repair the skin, and is beneficial to delaying the aging of the skin at the same time.
Owner:WANWANSHENG BIOTECHNOLOGY (SHENZHEN) CO LTD

UHPC (Ultra High Performance Concrete) based on carbon nanotube modified aggregate as well as preparation method and application of UHPC

The invention discloses UHPC based on carbon nanotube modified aggregate and a preparation method and application thereof, and belongs to the technical field of novel building materials. The raw materials comprise 1417 to 1517 parts of cement, 135 to 165 parts of silica fume, 35 to 43 parts of steel fiber, 800 to 1000 parts of sintered bauxite aggregate, 4.22 to 10.56 parts of carboxyl functionalized carbon nanotube, 410 to 510 parts of water and 6 to 12 parts of a water reducing agent; wherein the sintered bauxite aggregate is modified by carboxyl functionalized carbon nanotubes. The chemical reaction of oxygen-containing functional groups (carboxyl) in the carboxyl functionalized carbon nanotubes is utilized to form covalent bonds, the hydration reaction in cement is catalyzed and promoted, and the carboxyl functionalized carbon nanotubes provide more nucleation sites, so that the microstructure of the cement-based material is improved, and the integrity of the cement-based material is improved.
Owner:SHANDONG UNIV

Springback inhibitor for sprayed concrete as well as preparation method and application of springback inhibitor

The invention discloses a springback inhibitor for sprayed concrete as well as a preparation method and application of the springback inhibitor. The rebound inhibitor is prepared from the following components in percentage by mass: 2-5% of magnesium aluminum silicate, 19.8-29.8% of silica fume, 1-4% of a macromolecular tackifier, 2-5% of aluminum sulfate slag powder, 38-51% of superfine stone powder, 9-16% of fly ash microspheres, 1-2% of a water reducing agent, 2-3% of redispersible milk powder, 2-5% of inorganic mineral fibers and 0.01-0.2% of modified plant fibers. The springback inhibitor disclosed by the invention has a remarkable effect on reducing the springback rate of the sprayed concrete, and can enhance the water dispersibility resistance of the sprayed concrete and improve the cohesiveness of the sprayed concrete. The preparation method disclosed by the invention is simple in industry and easy for large-scale production.
Owner:THE THIRD ENG CO LTD OF CHINA RAILWAY SEVENTH GRP +2

Self-compacting concrete and preparation method thereof

The invention relates to the field of concrete, and particularly discloses self-compacting concrete and a preparation method thereof. The self-compacting concrete comprises the following raw materials in parts by weight: 320-370 parts of cement; 800 to 840 parts of coarse aggregate; 750 to 780 parts of fine aggregate; 12 to 19 parts of a fiber composition; 55 to 70 parts of fly ash; 20-35 parts of steel slag powder; 1-3 parts of a water reducing agent; 140 to 175 parts of water; 8-14 parts of an expanding agent; the fiber composition is hybrid fibers of steel fibers and sisal fibers, and the weight ratio of the steel fibers to the sisal fibers is (9-13): (3-6). The self-compacting concrete has the effects of inhibiting self-constriction and plastic constriction of the self-compacting concrete, reducing generation of harmful cracks and improving the strength and impermeability of the self-compacting concrete.
Owner:SHANWEI GUANGTOU CONSTR ENG CO LTD

Bacillus amyloliquefaciens and application thereof in biological fermentation feed

The invention discloses bacillus amyloliquefaciens with the characteristic of inhibiting mould growth and application of the bacillus amyloliquefaciens, and belongs to the field of microorganisms and fermentation engineering, the bacillus amyloliquefaciens is preserved in China General Microbiological Culture Collection Center on August 5, 2024, and the preservation number is CGMCC No.31538. The strain is bacillus amyloliquefaciens obtained by screening, separating and purifying from peasant pickles, and the strain can inhibit the growth of escherichia coli, clostridium perfringens and mould. The bacillus amyloliquefaciens disclosed by the invention solves the problem of insufficient effect of a microorganism mildew-proof method of the existing fermented feed, and the bacillus amyloliquefaciens is added into the biological fermented feed, so that the quantity of harmful microorganisms in the biological fermented feed can be effectively reduced, the generation of mycotoxin is inhibited, the feed is prevented from mildewing and going bad, and the shelf life of the feed is prolonged.
Owner:TANGRENSHEN GRP CO LTD

Microneedle patch loaded with sorafenib and copper-doped Prussian blue nano material and application of microneedle patch in in-situ triple-negative breast cancer treatment

The invention discloses a microneedle patch loaded with a sorafenib and copper-doped Prussian blue nano material and application of the microneedle patch in in-situ triple-negative breast cancer treatment. The sorafenib and the copper-doped Prussian blue nano material are loaded in a needle body of the microneedle patch. The microneedle patch can accurately deliver nanoparticles and sorafenib to tumor tissues, the chemical kinetics effect is enhanced through an efficient and mild photothermal therapy, the ferroptosis of triple negative breast cancer cells is enhanced through ferroptosis induced by the nanoparticles and sorafenib in cooperation with drugs, then cell death is induced, and the curative effect is improved. And a brand-new and promising treatment method is provided for in-situ triple-negative breast cancer treatment.
Owner:ANHUI MEDICAL UNIV

Silicon-carbon composite material and application thereof

The invention relates to the technical field of batteries, in particular to a silicon-carbon composite material and application thereof. The silicon-carbon composite material comprises a porous carbon material and nano silicon particles positioned in pores of the porous carbon material, in a dQ / dV curve of lithium intercalation for the first time of the silicon-carbon composite material, the ratio of the intensity value of a lithium intercalation peak at 0.30-0.45 V to the strongest peak value within 0-0.25 V is less than 0.05. The silicon-carbon composite material has the advantages of high compressive strength, high charge-discharge capacity and good cycle stability.
Owner:JIANGXI ZICHEN TECH CO LTD

Air preheater anti-blocking method for reducing NH3 escape and SO3 content

PendingCN119617456Arestore activityreduce escape rateFuel supply regulationEmission preventionAir preheaterPtru catalyst
The invention discloses an air preheater anti-blocking method for reducing NH3 escape and SO3 content, and relates to the field of air preheater anti-blocking. Comprising the steps of step-by-step soot blowing optimization, dynamic soot blowing parameter adjustment, ammonia escape precise control, coal type bin-divided blending, combustion parameter optimization control and wall temperature increase treatment. According to the invention, step-by-step soot blowing strengthens removal of ash on the surface of the catalyst and reduces the ammonia escape concentration through fixed-point retention and dynamic adjustment; the ammonia escape detection system monitors and adjusts the ammonia spraying amount in real time to ensure that the ammonia escape concentration is lower than 3 ppm, and generation of NH4HSO4 is reduced; the SO3 generation amount is reduced through coal type bin-dividing blending and combustion parameter optimization control, and the blocking risk is restrained from the source; in the wall temperature increasing treatment, the wall temperature is increased to 210 DEG C or above in a circulating air bin heating and single-side temperature increasing mode, and coagulated materials are promoted to be gasified and fall off. According to the method, the problem of blockage of the air preheater is effectively solved, and the operation efficiency and stability of a boiler system are improved.
Owner:CHINA RESOURCES POWER (LIUZHI) CO LTD

Flame-retardant silicon carbide ceramic rubber material and preparation method thereof

The invention relates to the technical field of rubber materials, and discloses a flame-retardant silicon carbide ceramic rubber material and a preparation method thereof. The flame-retardant silicon carbide ceramic rubber material is prepared by taking methyl vinyl silicone rubber as a main base material and adding MIL-100 (Fe, Co) coated CSiCNS, modified mica powder and other auxiliaries, not only has excellent high temperature resistance and corrosion resistance of silicone rubber, but also has excellent wear resistance of a ceramic material; wherein the MIL-100 (Fe, Co)-coated CSiCNS is prepared by taking a silicon carbide nanosheet as a substrate for modification, and is used as an inorganic flame-retardant component in the substrate, so that the flame-retardant property of the rubber material is improved; the modified mica powder serving as a ceramic forming filler not only endows the matrix with a certain flame retardant property, but also can be subjected to melting and eutectic reaction with the silicone rubber at high temperature to form a hard ceramic body, so that the flame retardant property of the matrix is further improved.
Owner:东莞市广亚新材料有限公司

In-situ control device and method for inhibiting metal additive manufacturing cracking

The invention discloses an in-situ control device and method for inhibiting metal additive manufacturing cracking, and belongs to the technical field of metal additive manufacturing. According to the device, the two propelling structures are arranged on the two sides of the core base plate with the transverse gap, the two propelling structures make contact with the core base plate from the two sides of the core base plate correspondingly, so that in the additive manufacturing process, the two propelling structures assist in extruding shrinkage of the core base plate from the two sides of the core base plate; and it is ensured that the shrinkage speed of the core substrate can be matched with the shrinkage speed required by the formed part. The device disclosed by the invention is a device for regulating and controlling the local structure deformation of the substrate in situ, and the local deformation of the substrate is regulated and controlled in real time in the additive manufacturing process, so that the distribution and evolution of a stress field are regulated, the tensile stress is successfully converted into the pressure stress, and the generation and expansion of cracks are effectively inhibited.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Uric acid reducing composition containing fructus gardeniae and preparation method of uric acid reducing composition

The invention provides a uric acid reducing composition containing fructus gardeniae and a preparation method of the uric acid reducing composition, and belongs to the technical field of medicines. The preparation method comprises the following steps: fermenting mulberry leaves, chicory, cape jasmine and kudzu vine roots through lactobacillus rhamnosus and bifidobacterium longum, separating probiotics from fermentation liquor, adding immobilized ionic liquid into the fermentation liquor, introducing carbon dioxide for adsorption, filtering, adding solids into ethanol, heating for desorption, concentrating to obtain an extract 1, precipitating filtrate with ethanol to obtain an extract 2, and carrying out freeze-drying to obtain the folium mori-chicory-cape jasmine extract. The preparation method comprises the following steps: embedding probiotics together with sodium alginate to prepare a uric acid-reducing embedding material, and uniformly mixing the uric acid-reducing embedding material with the extract 1, vitamin C and tea polyphenol to prepare the uric acid-reducing composition containing fructus gardeniae. The prepared uric acid reducing composition containing fructus gardeniae can promote uric acid excretion, inhibit sodium urate crystallization, improve the antioxidant effect, repair intestinal barriers, relieve inflammation, inhibit xanthine oxidase (XOD) activity and expression and reduce the blood uric acid level, has a good uric acid reducing effect and has a wide application prospect.
Owner:FOSHAN GOLDEN HEALTH TECH CO LTD +1

Multifunctional DNA nano-material, preparation method thereof and application of multifunctional DNA nano-material in treatment of traumatic brain injury secondary encephaledema

The invention belongs to the field of biological materials, and particularly relates to a multifunctional DNA nanometer material, a preparation method and application of the multifunctional DNA nanometer material in treatment of traumatic brain injury secondary encephaledema. The multifunctional DNA nano material comprises a plurality of deoxyribozyme (DNAzyme) targeting C1q mRNA (messenger Ribonucleic Acid) and a repeating unit which is integrally connected with G-quadruplex / Hemin in series, wherein the G-quadruplex / Hemin is labeled by streptavidin SA and biotin and is used for scavenging free radicals. The DNAzyme for silencing the C1q gene of the mouse is designed on the basis of a bioinformatics method, and the C1q gene overexpressed in an inflammation model can be knocked down to an approximate normal level. The RCA technology mediated self-assembled nano material SA-B / H has excellent enzyme mimetic activity, can effectively remove free radicals such as H2O2 and O2 <.->, and has the potential of in-vivo oxidation resistance. In-vitro experiments prove that SA-B / H can effectively relieve high-level oxidative stress of cells caused by H2O2 stimulation.
Owner:TIANJIN UNIV

Preparation method of spherical lithium manganese iron phosphate positive electrode material with high compaction density

The invention discloses a preparation method of a spherical lithium manganese iron phosphate positive electrode material with high compaction density, relates to the technical field of preparation of a lithium battery positive electrode material, and aims to improve the compaction density of the lithium manganese iron phosphate positive electrode material through low-cost, simple and controllable steps. The preparation method comprises the following steps: grinding and refining a lithium source, a phosphorus source, an iron source, a manganese source and a carbon source to obtain a primary precursor with a micro-nano size; slowly adding a flocculating agent into the primary precursor slurry, dividing the primary precursor slurry into at least two parts, respectively centrifuging at different rotating speeds, and mixing each part of centrifuged slurry to obtain high-solid-content precursor aqueous slurry with different particle size distributions; adjusting the viscosity of the precursor water-based slurry by using a thickening agent until the viscosity meets the granulation requirement, and then carrying out secondary granulation treatment to obtain spherical precursor powder; and in a protective gas atmosphere, calcining the powder, and cooling to obtain the high-compaction-density lithium manganese iron phosphate material. The method is simple and easy to control, low in cost, high in production efficiency and good in product compaction density.
Owner:SINOSTEEL ANHUI TIANYUAN TECH +1

Whitening and moisturizing essence as well as preparation process and application thereof

ActiveCN119499147Astay hydratedInhibition lossCosmetic preparationsToilet preparationsBiotechnologyAlthaea officinalis flower extract
The invention provides whitening and moisturizing essence as well as a preparation process and application thereof, and belongs to the technical field of cosmetics. The essence is prepared from tranexamic acid, nicotinamide, macromolecular hyaluronic acid, micromolecular hyaluronic acid, hexapeptide-2, an althaea rosea flower extract, a rhodiola sachalinensis extract, a glycyrrhiza glabra extract, a coast pine needle extract, a polyhydric alcohol humectant, vegetable fat and the like. Wherein the hollyhock flower extract, the rhodiola sachalinensis extract, the glycyrrhiza glabra extract and the coast pine needle extract are respectively obtained by adopting a special enzymolysis method. The tranexamic acid and the nicotinamide are used for synergistically whitening, the hyaluronic acid, the polyhydric alcohols and the vegetable fat are used for jointly moisturizing, the plant extract is used for enhancing oxidation resistance, whitening and safety, the components are ensured to be uniform and stable through a reasonable preparation process, and the effect of the essence is favorably improved.
Owner:GUANGZHOU ZHUANGZE BIO TECH CO LTD

Preparation method and application of iron-doped molybdenum disulfide / polymer-based composite solid electrolyte

The invention discloses a preparation method and application of an iron-doped molybdenum disulfide / polymer-based composite solid-state electrolyte, and relates to the technical field of solid-state batteries. After the iron element is doped, defects are introduced into the structure of the modified molybdenum disulfide, phase change is induced, dissociation of the lithium salt is promoted through synergism of the modified molybdenum disulfide and the iron element, and more free lithium ions are released; and meanwhile, the proportion of an amorphous region of the polymer electrolyte is increased, so that the ionic conductivity is improved, and the oxidation resistance is enhanced. In addition, the iron-doped molybdenum disulfide can effectively catalyze decomposition of lithium salt anions, and construction of a uniform and stable solid electrolyte interface (SEI) layer on the surface of the electrode is facilitated. The all-solid-state lithium metal battery assembled based on the modified solid electrolyte shows excellent electrochemical performance.
Owner:XIANGTAN UNIV

Auxiliary machining device for inertia friction welding of dissimilar materials and working method of auxiliary machining device

The invention provides an inertia friction welding auxiliary machining device for dissimilar materials and a working method of the inertia friction welding auxiliary machining device, and belongs to the technical field of friction welding. The problem that in the prior art, the heat preservation effect cannot be improved at any time of welding according to the process requirement is solved. The device comprises a main shaft side box body, a main shaft side clamp, an external blowing assembly, a main shaft side to-be-welded piece, a movable sliding table box body, a lathe bed, a tailstock side clamp, a tailstock side to-be-welded piece and a heating mechanism, the main shaft side box body is installed on one side of the lathe bed, and the movable sliding table box body is installed on the other side of the lathe bed in a sliding mode through a movable sliding table rail; the main shaft side clamp is installed in the main shaft side box body through the main shaft fixing seat, the external blowing assembly is arranged on the outer side of a welding area of a main shaft side to-be-welded piece, the tailstock side clamp is installed in the movable sliding table box body through the tailstock fixing seat, and the heating mechanism is arranged on the outer side of the welding area of the tailstock side to-be-welded piece. The device is mainly used for protecting the welding area of friction welding.
Owner:HARBIN WELDING INST LTD