1679results about "Laser surgery" patented technology

Provided are multi-wavelength phototherapy devices, systems and methods for the treatment of a disorder or disease, including multi-wavelength low level light therapy (“PBM”), in particular to multi-wavelength PBM and other phototherapy systems and methods for improving functionality in and / or restoring functionality to a cell and / or tissue through the coordinated and targeted delivery to the cell or tissue of two or more doses of light having distinct wavelengths, wherein the two or more doses of light, when delivered in a coordinated fashion, can stimulate the activity of two or more light sensitive factors that, when activated, provide and / or enhance a desired target cell functionality. Ophthalmic phototherapy devices, systems, and treatment methods to expose an eye to selected multi-wavelengths of light to promote the healing of damaged or diseased eye tissue. The devices include a housing having an interior; an eyepiece disposed on the housing and configured and arranged for placement of an eye of the patient adjacent the eyepiece; a first light source producing a first light beam having a first therapeutic wavelength and disposed within the housing; a second light source producing a second light beam having a second therapeutic wavelength and disposed within the housing, where the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm.

In an ophthalmic surgical laser system, a patient interface device for coupling a patient's eye to the laser system includes a lens cone with a frustoconical shaped shell for coupling to the laser system and a suction ring for coupling to the patient's eye, the lens cone and the suction ring being joined together by clamping. A cap is provided for use with the lens cone as an installation aid. In the configuration supplied to the user, the lens cone is partially embedded in and snapped to the cap. The cap has a portion with a relatively large diameter and multiple ribs for easy handling. The user holds the cap to install the lens cone on the laser system, and pulls the cap to unsnap it from the lens cone. The lens cone is attached to the laser system with a bayonet mount that provides tactile feedback to the user.

Hardware and software system solutions provide real-time, interactive predictive simulation of an eye (e.g., a human eye or animal eye). A predictive simulation of an individual eye may be created using finite element models (FEM) of ocular structures involved in optical biomechanics, including ocular adjustments. Unlike previous ocular models, the present FEM described herein is a three-dimensional FEM of an adjustment mechanism, including but not limited to the anterior of the human eye that simulates ciliary muscle fiber contraction actions, to predict the dynamic deformation of the crystalline lens required to adjust visual power variations, referred to herein as' Central Visual Power '(COP). The present FEM further describes aqueous / vitreous outflow and fluid flow mechanisms referred to herein as "hydrodynamics". The virtual FEM further describes posterior ocular biomechanics that simulates the actions of the Bruch membrane, retina, vitreous and sieve plates during pre-stretching, non-regulatory and regulatory actions of the eye.

In certain embodiments, ophthalmic laser system includes an auxiliary light system, laser system, imaging system, and computer. The auxiliary light system directs auxiliary light towards a test target according to a planned test pattern to yield one or more actual auxiliary spots of an actual test pattern on the test target. The planned test pattern indicates one or more planned auxiliary spots located relative to a planned laser spot in a predetermined manner. The laser system directs a laser beam to yield an actual laser spot of the actual test pattern on the test target. The imaging system generates a digital image of the actual test pattern. The computer analyzes the digital image to compare the actual to the planned test pattern, detect a deviation of the actual from the planned test pattern, identify an issue indicated by the deviation, and provide output in response to the issue.

Shape-stabilized collagen scaffolds and methods of obtaining such scaffolds are disclosed. Stroma can be harvested, for example, from human or porcine corneal stroma and shaped during excision or in a separate step after excision. Following shaping (and preferably decellularization), the excised stroma portion is subject to pressure, force or vacuum to reduce fluid content and then irradiated or otherwise treated to induce crosslinking of collagen chains or fibrils. In one embodiment, the scaffold can be compacted by removing some or all of the water from the scaffold, and rehydrating the scaffold in a controlled manner (e.g., in a mold or other confining space) such that the scaffold takes a desired compacted shape; and then crosslinking at least a portion of the scaffold to mechanically strengthen it and inhibit subsequent swelling. Various sources of energy can be employed to induce crosslinking of collagen including, for example, ultraviolet (UV) radiation. The scaffolds can also be selectively densified or patterned. The invention is particularly useful in forming stable lenticules of enhanced stiffness and sufficient optical clarity for intracorneal implantation in additive ocular surgery.

A modular ophthalmology device comprising: a first optical device having a light source and an imaging sensor, a first input coupling having an optical interface connection and a physical interface connection for aligning and securing an input optical module, a first optical output, an optical pathway and an output coupling securing a third optical device.

A surgical tool for shearing tissue at a target surgical site, the surgical tool comprising a cannula assembly with a distal end and a proximal end, a cannula opening into the lumen of the cannula at the distal end, a cutting device coupled to the distal end and within the cannula opening, and an axial ball joint coupled to the proximal end of the cannula assembly, that when rotated, causes the cutting device at the distal end to rotate about a longitudinal axis passing axially through the lumen of the cannula assembly, so as to shear a portion of tissue at a target surgical site.

An ophthalmological device and system is described that allows the simultaneous imaging of an eye using both scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Further the device and system is capable of targeting and delivering a treatment laser for treatment of an eye condition. The system further can include a machine learning algorithm to provide a suggested treatment procedure.

In certain embodiments, an ophthalmic laser system includes a laser system, imaging system, and computer. The laser system accesses a planned test pattern of planned laser spots and directs a laser beam towards a test target located at a target plane according to the planned test pattern to yield an actual test pattern of actual laser spots on the test target. The actual laser spots correspond to the planned laser spots. The imaging system has a digital camera that generates a digital image of the actual test pattern. The computer analyzes the digital image to: compare the actual test pattern to the planned test pattern; detect a deviation of the actual from the planned test pattern; identify an issue indicated by the deviation; and provide output in response to the identified issue.

The invention relates to the technical field of femtosecond laser, and discloses a multifunctional ophthalmology femtosecond device and a use method, and the device comprises a scanning imaging module which is used for emitting a detection light beam and carrying out OCT imaging; the femtosecond laser scanning module is used for receiving the detection light beam and irradiating the detection light beam to the target tissue; the femtosecond laser scanning module is also used for generating femtosecond laser and focusing the femtosecond laser to the target tissue; the operating microscope module is used for receiving the detection light beam and irradiating the detection light beam to a target tissue; the operating microscope module is also used for carrying out microscope imaging. According to the method, the optical coherence tomography technology is fused, more imaging information is added on the basis of an original visible light image, the re-alignment precision can be effectively improved, and the problem that a separation hook enters a wrong corneal lens layer is avoided.

A system (20) includes a laser (48), configured to irradiate a target site (41) in an iris (35) of an eye (25), and a controller (44). The controller is configured to identify, in one or more images of at least part of the iris, an indication of fluid flow through the target site, and in response to identifying the indication, inhibit the laser from further irradiating the target site. Other embodiments are also described.

Images of a patient's eye can be imaged and the images processed to detect and track floaters within the patient's eye. The floater detection and tracking can be used to identify characteristics of the floaters as well as possibly perform laser treatment of the floaters.

Features can be tracked across frames. The features are first identified in an initial frame using an image processing technique which may take a relatively long time to complete, such as the length of several frames. When the features are being identified within the initial frame, subsequent frames are stored in a fast track buffer and once the features are identified in the initial image, the features can be tracked across the frames in the fast track buffer using a relatively fast process, such a one that is able to process the buffer at a higher frame rate than the frames are received at.

A therapeutic laser for use in treating ophthalmological conditions can be modulated by a spatial light modulation device in order to focus the therapeutic laser on a plurality of target locations simultaneously.

A computer program is provided, comprising an artificial intelligence-based model, wherein the computer program is designed to, when executed by a computer, induce the computer, by means of the model, to determine a treatment plan for refractive eye surgery based on information characterizing a patient and information characterizing a refractive error in one of the patient's eyes that is to be corrected by means of refractive eye surgery.

Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable intraocular lens can comprise an optic portion and one or more haptics. The optic portion can comprise an anterior element, a posterior element, and a fluid-filled optic chamber. At least part of the optic portion can be made of a composite material. The base power of the optic portion can be configured to change in response to an external energy directed at the composite material.

Devices and methods are disclosed for improved followability in laser-based ocular procedures. In some embodiments, an ophthalmic instrument comprises a projection located at the distal end of the shaft or cannula, the projection having a distal surface in proximity to the distal end of the optical fiber, the distal surface adapted to be positioned facing the treatment area during use of the ophthalmic instrument. An example method includes delivering laser energy through an optical fiber to the treatment area, wherein the distal surface of the projection inhibits bubbles formed during the procedure from moving distally away from the distal end of the ophthalmic instrument.

An ophthalmological device and system is described that allows the simultaneous imaging of an eye using both scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Further the device and system is capable of targeting and delivering a treatment laser for treatment of an eye condition.

Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be affected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

Devices and methods are disclosed for improved removal of cortical material. In certain embodiments, an ophthalmic surgical instrument includes a shaft having a distal end configured to be inserted into an eye of a patient toward a treatment area, and a projection located at the distal end of the shaft, the projection having a distal surface that extends at an angle to a longitudinal axis of the shaft, the distal surface configured to be positioned facing the treatment area during use of the ophthalmic surgical instrument. The projection is located on a tip or a sleeve of the ophthalmic surgical instrument.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and / or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user's body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

Systems and methods for compensating for tilt of an intraocular lens (IOL) and systems and methods for adjusting an IOL are disclosed herein. For example, one of the methods may include capturing one or more optical coherence tomography (OCT) images of a subject's eye while implanting the IOL within the subject's eye. The method may further include generating a fixation target such that the fixation target is visible to an eye of the subject; and moving the fixation target until the lateral plane of the IOL is perpendicular or substantially perpendicular to the optical axis of the ophthalmic system. The method may also include directing a laser beam generated by a laser of the ophthalmic system at the IOL.

The invention discloses a center positioning system and method for a femtosecond laser ophthalmic corneal refraction operation, and relates to the technical field of image processing. The method comprises the following steps of S1, performing multi-source data synchronous acquisition on eyeballs of a patient before an operation; s2, fusing and preprocessing the collected multi-source data; s3, establishing an eyeball dynamics method, outputting six-degree-of-freedom position data in real time, and predicting the position of a laser action point; s4, dynamically adjusting the dual coordinate system according to the cornea; s5, constructing a real-time feedback system, and realizing closed-loop control, safety boundary control and a fault-tolerant mechanism; and S6, generating parameters of an operation process, constructing a four-dimensional cutting model, and performing path planning of the laser model. According to the method, the OCT, the Placido ring and the iris vein composite features are combined, the positioning precision is improved, Kalman filtering and neural network prediction compensation are utilized, eyeball movement is tracked in real time, and the accuracy of operation pupil positioning is improved.

The invention relates to a method for providing control data for an ophthalmic laser (12) of a treatment device (10).The procedure comprises the following steps: determining a preoperative corneal thickness profile (24) of a cornea (16) of a human or animal eye from predetermined examination data; determining a target corneal thickness profile (26) of the cornea (16), wherein at least one corneal thickness of the target corneal thickness profile (26) is set to a predetermined corneal thickness value (28) present at at least one predetermined position of the preoperative corneal thickness profile (24); determining tissue removal data to generate the target corneal thickness profile (26), wherein in the tissue removal data only tissue (14) at positions between the preoperative corneal thickness profile (24) and the target corneal thickness profile (26) is defined as tissue (14) to be removed; and providing control data for controlling the ophthalmic laser (12), which includes the tissue removal data.

Embodiments described herein relate to systems and methods of delivering medicinal components to target regions of an eye of a subject and / or patient. In some aspects, an apparatus includes a housing; a medicament container configured to accommodate a medicinal component; a sensor configured to measure a physical property of a subject; and an injector coupled to the medicament container and configured to produce a stream of the medicinal component directed towards a region of the eye of the subject based on the measured physical property.

The invention relates to the technical field of ophthalmology medical treatment, in particular to an excimer laser cutting parameter optimization method for presbyopia correction, which comprises the following steps: (1) collecting eye data of a patient: collecting eye structure data and vision information of the patient; (2) establishing a personalized eye model: constructing a personalized eye three-dimensional model of the patient based on the collected eye data; (3) determining an optimization objective function: comprehensively considering the correction effects of far vision, near vision and middle vision and the risk of postoperative complications, and determining the optimization objective function; and (4) constructing a cutting parameter constraint condition: setting the cutting parameter constraint condition according to the eye condition of the patient. The method aims at solving the problems that in the prior art, an excimer laser cutting parameter optimization method for presbyopia correction is insufficient in the aspects of individuation, accuracy, comprehensiveness, safety and the like.

A system for performing ophthalmic surgery includes a robotic positioning system including an end effector. The robotic positioning system is configured to position the end effector with at least five degrees of freedom. An ophthalmic surgical instrument is mounted to the end effector along with an accessory device configured to facilitate performance of an ophthalmic treatment by the ophthalmic surgical instrument. The robotic positioning system may be controlled to enforce anatomical boundaries and implement predefined motion profiles.

The present disclosure relates to an ophthalmological device for surgical treatment of a cornea of an eye, the ophthalmological device comprising a laser source, a focusing optics, a scanner system and an electronic circuit. The electronic circuit is configured to control a first scanner device of the scanner system to move the focal spot with a first scanning speed along a line, thereby forming a scan line, to control a second scanner device of the scanner system to move the scan line with a second scanning speed along a predetermined processing path, which extends inside the cornea, for treating the cornea, and to control the ophthalmological device to vary at least one of: a geometrical parameter of the scan line or a physical parameter of the scan line, along the predetermined processing path.

A method of lamellar corneal graft implantation is disclosed herein. The method includes the steps of: (i) forming one or more intrastromal incisions in a cornea of an eye of a patient; (ii) removing a cut portion of the cornea defined by the one or more intrastromal incisions from the eye of the patient; (iii) applying laser energy to a lamellar corneal graft using an excimer laser so as to modify the refractive power of the lamellar corneal graft, the lamellar corneal graft being in the form of a autologous corneal graft or a homologous corneal graft; and (iv) implanting the lamellar corneal graft into the eye of the patient in a location previously occupied by the cut portion of the cornea so as to correct the refractive power of the eye of the patient.

The present disclosure provides a system capable of determining a first plurality of focal lengths associated with a respective plurality of locations in a plane orthogonal to a laser beam, for each location of the plurality of locations, determining a second plurality of focal lengths associated with the respective plurality of locations, determining a plurality of intensity values ​​associated with each of the plurality of intermediate focal lengths, each intermediate focal length being greater than a respective focal length of the first plurality of focal lengths associated with that location, determining an intermediate focal length each associated with a maximum intensity value, determining the focal length as the intermediate focal length, and determining a depth of at least one incision in the eye based on a difference between at least each of the second plurality of focal lengths and a respective one of the first plurality of focal lengths.