2391results about "Laser surgery" patented technology

Provided are multi-wavelength phototherapy devices, systems and methods for the treatment of a disorder or disease, including multi-wavelength low level light therapy (“PBM”), in particular to multi-wavelength PBM and other phototherapy systems and methods for improving functionality in and / or restoring functionality to a cell and / or tissue through the coordinated and targeted delivery to the cell or tissue of two or more doses of light having distinct wavelengths, wherein the two or more doses of light, when delivered in a coordinated fashion, can stimulate the activity of two or more light sensitive factors that, when activated, provide and / or enhance a desired target cell functionality. Ophthalmic phototherapy devices, systems, and treatment methods to expose an eye to selected multi-wavelengths of light to promote the healing of damaged or diseased eye tissue. The devices include a housing having an interior; an eyepiece disposed on the housing and configured and arranged for placement of an eye of the patient adjacent the eyepiece; a first light source producing a first light beam having a first therapeutic wavelength and disposed within the housing; a second light source producing a second light beam having a second therapeutic wavelength and disposed within the housing, where the second therapeutic wavelength differs from the first therapeutic wavelength by at least 25 nm.

Adjustable flow glaucoma shunts are disclosed herein. In one embodiment, for example, an adjustable flow shunt can include an outflow drainage tube having a proximal inflow region and a distal outflow region. The proximal inflow region can include aperture(s) defining a fluid inlet area positioned to allow fluid to flow therethrough. The shunt further comprises an inflow control assembly at the proximal inflow region. The inflow control assembly can include a control element configured to slidably engage the proximal inflow region and a spring element. The spring element is configured to be activated by non-invasive energy and, upon activation, slidably move the control element along the proximal inflow region such that (a) the one or more apertures are accessible and have a first fluid flow cross-section or (b) the one or more apertures are at least partially covered by the control element and have a second, different fluid-flow cross-section.

The use of machine learning (ML) can provide good results in annotating features present in images. However training the ML process can require a large amount of training images that have had the individual features correctly annotated. An ML process and training technique is described that can train and use a classifier in order to annotate features in an image. The training uses saliency loss propagation (SLP) to train the classifier on portions of images that include important features.

Disclosed herein are systems and methods for compensating for a tilt of an intraocular lens (IOL) and systems and methods for adjusting the IOL. For example, one of the methods can comprise capturing one or more optical coherence tomography (OCT) images of an eye of a subject when the IOL is implanted within the eye of the subject. The method can also comprise generating a fixation target such that the fixation target is visible to the eye of the subject and moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system. The method can also comprise directing a laser beam generated by a laser of the ophthalmic system at the IOL.

In an ophthalmic surgical laser system, a patient interface device for coupling a patient's eye to the laser system includes a lens cone with a frustoconical shaped shell for coupling to the laser system and a suction ring for coupling to the patient's eye, the lens cone and the suction ring being joined together by clamping. A cap is provided for use with the lens cone as an installation aid. In the configuration supplied to the user, the lens cone is partially embedded in and snapped to the cap. The cap has a portion with a relatively large diameter and multiple ribs for easy handling. The user holds the cap to install the lens cone on the laser system, and pulls the cap to unsnap it from the lens cone. The lens cone is attached to the laser system with a bayonet mount that provides tactile feedback to the user.

Hardware and software system solutions provide real-time, interactive predictive simulation of an eye (e.g., a human eye or animal eye). A predictive simulation of an individual eye may be created using finite element models (FEM) of ocular structures involved in optical biomechanics, including ocular adjustments. Unlike previous ocular models, the present FEM described herein is a three-dimensional FEM of an adjustment mechanism, including but not limited to the anterior of the human eye that simulates ciliary muscle fiber contraction actions, to predict the dynamic deformation of the crystalline lens required to adjust visual power variations, referred to herein as' Central Visual Power '(COP). The present FEM further describes aqueous / vitreous outflow and fluid flow mechanisms referred to herein as "hydrodynamics". The virtual FEM further describes posterior ocular biomechanics that simulates the actions of the Bruch membrane, retina, vitreous and sieve plates during pre-stretching, non-regulatory and regulatory actions of the eye.

Disclosed herein are systems and methods for compensating for a tilt of an intraocular lens (IOL) and systems and methods for adjusting the IOL. For example, one of the methods can comprise capturing one or more optical coherence tomography (OCT) images of an eye of a subject when the IOL is implanted within the eye of the subject. The method can also comprise generating a fixation target such that the fixation target is visible to the eye of the subject and moving the fixation target until a transverse plane of the IOL is perpendicular or substantially perpendicular to an optical axis of an ophthalmic system. The method can also comprise directing a laser beam generated by a laser of the ophthalmic system at the IOL.

In certain embodiments, ophthalmic laser system includes an auxiliary light system, laser system, imaging system, and computer. The auxiliary light system directs auxiliary light towards a test target according to a planned test pattern to yield one or more actual auxiliary spots of an actual test pattern on the test target. The planned test pattern indicates one or more planned auxiliary spots located relative to a planned laser spot in a predetermined manner. The laser system directs a laser beam to yield an actual laser spot of the actual test pattern on the test target. The imaging system generates a digital image of the actual test pattern. The computer analyzes the digital image to compare the actual to the planned test pattern, detect a deviation of the actual from the planned test pattern, identify an issue indicated by the deviation, and provide output in response to the issue.

Shape-stabilized collagen scaffolds and methods of obtaining such scaffolds are disclosed. Stroma can be harvested, for example, from human or porcine corneal stroma and shaped during excision or in a separate step after excision. Following shaping (and preferably decellularization), the excised stroma portion is subject to pressure, force or vacuum to reduce fluid content and then irradiated or otherwise treated to induce crosslinking of collagen chains or fibrils. In one embodiment, the scaffold can be compacted by removing some or all of the water from the scaffold, and rehydrating the scaffold in a controlled manner (e.g., in a mold or other confining space) such that the scaffold takes a desired compacted shape; and then crosslinking at least a portion of the scaffold to mechanically strengthen it and inhibit subsequent swelling. Various sources of energy can be employed to induce crosslinking of collagen including, for example, ultraviolet (UV) radiation. The scaffolds can also be selectively densified or patterned. The invention is particularly useful in forming stable lenticules of enhanced stiffness and sufficient optical clarity for intracorneal implantation in additive ocular surgery.

The invention discloses a femtosecond laser refractive surgery cutting center positioning method and device, and relates to the field of refractive surgery cutting center localization, and the method comprises the steps: obtaining a lying position eye image and a sitting position eye image of a to-be-operated patient under set illumination brightness, and determining a first iris image and a first relative position; determining a second iris image according to the lying position eye image; according to the first iris image and the second iris image, a first eyeball rotation angle is determined, a second visual axis center and a second relative position of the patient to be operated can be further calculated, negative pressure suction is guided, and before negative pressure suction and after the center of a negative pressure suction ring is aligned with the second visual axis center, if movement occurs, the first eyeball rotation angle is determined; a third iris image in the negative pressure suction process is shot, then the center of a third visual axis is calculated, the center of the negative pressure suction ring is aligned to the center of the third visual axis, and the center of the third visual axis serves as the cutting center for operation. The cutting center can be accurately positioned.

Tracking of a patient's retina, or eye movements, may be useful when treating the patient's eye. The tracking may be done using an imaging system and may use two tracking processes. A first tracking process may determine eye movement based on a comparison between full frames of images. The second tracking process determines eye movement based on partial frames, or strips, of the images. The first tracking process must wait until the full frame is received, while the second tracking process may be performed quicker as it only requires a portion of the image to be received.

A modular ophthalmology device comprising: a first optical device having a light source and an imaging sensor, a first input coupling having an optical interface connection and a physical interface connection for aligning and securing an input optical module, a first optical output, an optical pathway and an output coupling securing a third optical device.

A surgical tool for shearing tissue at a target surgical site, the surgical tool comprising a cannula assembly with a distal end and a proximal end, a cannula opening into the lumen of the cannula at the distal end, a cutting device coupled to the distal end and within the cannula opening, and an axial ball joint coupled to the proximal end of the cannula assembly, that when rotated, causes the cutting device at the distal end to rotate about a longitudinal axis passing axially through the lumen of the cannula assembly, so as to shear a portion of tissue at a target surgical site.

An ophthalmological device and system is described that allows the simultaneous imaging of an eye using both scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Further the device and system is capable of targeting and delivering a treatment laser for treatment of an eye condition. The system further can include a machine learning algorithm to provide a suggested treatment procedure.

In certain embodiments, an ophthalmic laser system includes a laser system, imaging system, and computer. The laser system accesses a planned test pattern of planned laser spots and directs a laser beam towards a test target located at a target plane according to the planned test pattern to yield an actual test pattern of actual laser spots on the test target. The actual laser spots correspond to the planned laser spots. The imaging system has a digital camera that generates a digital image of the actual test pattern. The computer analyzes the digital image to: compare the actual test pattern to the planned test pattern; detect a deviation of the actual from the planned test pattern; identify an issue indicated by the deviation; and provide output in response to the identified issue.

Devices, methods, and systems related to a robot-assisted ophthalmic surgical platform for cataract surgery are provided. For example, there is a computer-controlled ophthalmic robotic surgical system including: a multimodal visualization subsystem; a tool exchange system; a plurality of robotic arms configured to receive and manipulate surgical tools; an artificial intelligence (Al) subsystem configured to produce outputs using the imaging data from the visualization subsystem, including: acquired data of the operative eye, extracted patient-specific metrics from the data for the operative eye; a trajectory planner configured to determine a trajectory path for a selected one of a plurality of surgical tools; and a control system configured to receive and execute the determined trajectory path on the operative eye, in which the trajectory path is modified in real-time based on data from one or more of the visualization subsystem and Al subsystem.

The invention relates to the technical field of femtosecond laser, and discloses a multifunctional ophthalmology femtosecond device and a use method, and the device comprises a scanning imaging module which is used for emitting a detection light beam and carrying out OCT imaging; the femtosecond laser scanning module is used for receiving the detection light beam and irradiating the detection light beam to the target tissue; the femtosecond laser scanning module is also used for generating femtosecond laser and focusing the femtosecond laser to the target tissue; the operating microscope module is used for receiving the detection light beam and irradiating the detection light beam to a target tissue; the operating microscope module is also used for carrying out microscope imaging. According to the method, the optical coherence tomography technology is fused, more imaging information is added on the basis of an original visible light image, the re-alignment precision can be effectively improved, and the problem that a separation hook enters a wrong corneal lens layer is avoided.

A system (20) includes a laser (48), configured to irradiate a target site (41) in an iris (35) of an eye (25), and a controller (44). The controller is configured to identify, in one or more images of at least part of the iris, an indication of fluid flow through the target site, and in response to identifying the indication, inhibit the laser from further irradiating the target site. Other embodiments are also described.

Images of a patient's eye can be imaged and the images processed to detect and track floaters within the patient's eye. The floater detection and tracking can be used to identify characteristics of the floaters as well as possibly perform laser treatment of the floaters.

Features can be tracked across frames. The features are first identified in an initial frame using an image processing technique which may take a relatively long time to complete, such as the length of several frames. When the features are being identified within the initial frame, subsequent frames are stored in a fast track buffer and once the features are identified in the initial image, the features can be tracked across the frames in the fast track buffer using a relatively fast process, such a one that is able to process the buffer at a higher frame rate than the frames are received at.

Systems, devices, and methods for treating a glaucomatous eye are provided. An amount of pulsed laser energy is delivered to the pars plana of the eye by a hand-holdable device which comprises a hand-holdable elongate member and a contact member disposed on an end of the elongate member. A contact surface of the contact member is placed in direct contact with the eye so that a reference edge of the contact member aligns with the limbus and a treatment axis defined by the elongate member is angularly offset from the optical axis of the eye. The amount of pulsed laser energy delivered is insufficient to effect therapeutic photocoagulation but is sufficient to increase uveoscleral outflow so as to maintain a reduction from pre-laser treatment intraocular pressure. Amounts of pulsed laser energy will be transmitted to a circumferential series of tissue regions of the eye.

A therapeutic laser for use in treating ophthalmological conditions can be modulated by a spatial light modulation device in order to focus the therapeutic laser on a plurality of target locations simultaneously.

The invention relates to a method for providing control data for an ophthalmic laser (12) of a treatment device (10). A control unit (18) determines (S10) corneal parameters of an anterior surface (24) of a cornea (16) from predetermined examination data; determines (S12) an epithelial map of an epithelial layer (26) of the cornea (16) from the predetermined examination data, wherein the thickness of the epithelial layer (26) is provided in the epithelial map; calculates (S14) a stromal wavefront map as a function of the determined corneal parameters of the anterior surface (24) of the cornea and the determined epithelial map; determines (S16) correction data for correcting a refractive error based on the stromal wavefront map; and provides (S18) the control data comprising the correction data determined on the basis of the stromal wavefront map.

A computer program is provided, comprising an artificial intelligence-based model, wherein the computer program is designed to, when executed by a computer, induce the computer, by means of the model, to determine a treatment plan for refractive eye surgery based on information characterizing a patient and information characterizing a refractive error in one of the patient's eyes that is to be corrected by means of refractive eye surgery.

Disclosed are adjustable intraocular lenses and methods of adjusting intraocular lenses post-operatively. In one embodiment, an adjustable intraocular lens can comprise an optic portion and one or more haptics. The optic portion can comprise an anterior element, a posterior element, and a fluid-filled optic chamber. At least part of the optic portion can be made of a composite material. The base power of the optic portion can be configured to change in response to an external energy directed at the composite material.

Devices and methods are disclosed for improved followability in laser-based ocular procedures. In some embodiments, an ophthalmic instrument comprises a projection located at the distal end of the shaft or cannula, the projection having a distal surface in proximity to the distal end of the optical fiber, the distal surface adapted to be positioned facing the treatment area during use of the ophthalmic instrument. An example method includes delivering laser energy through an optical fiber to the treatment area, wherein the distal surface of the projection inhibits bubbles formed during the procedure from moving distally away from the distal end of the ophthalmic instrument.

Methods and systems for planning and performing a corneal laser ablation procedure that may comprise a wavefront aberrometer and a corneal topography measuring device. Data from each of these devices may be compared for generating an astigmatism treatment to be incorporated into a laser ablation treatment map. Corrections derived from epithelial thickness measurements may also be incorporated into the treatment map.

An ophthalmological device and system is described that allows the simultaneous imaging of an eye using both scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Further the device and system is capable of targeting and delivering a treatment laser for treatment of an eye condition.

Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be affected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

Devices and methods are disclosed for improved removal of cortical material. In certain embodiments, an ophthalmic surgical instrument includes a shaft having a distal end configured to be inserted into an eye of a patient toward a treatment area, and a projection located at the distal end of the shaft, the projection having a distal surface that extends at an angle to a longitudinal axis of the shaft, the distal surface configured to be positioned facing the treatment area during use of the ophthalmic surgical instrument. The projection is located on a tip or a sleeve of the ophthalmic surgical instrument.