170 results about "Cataracts" patented technology

The invention relates to the technical field of intelligent medical treatment, and discloses a cataract surgery navigation control method based on multi-modal fusion, which comprises the following steps: carrying out lightweight preprocessing on an eye fundus image, ultrasonic probe data, a corneal topographic map and intraocular pressure parameters through an edge computing architecture, and constructing an efficient feature extraction network by adopting a knowledge distillation technology; self-adaptive feature fusion is realized based on an uncertainty quantification mechanism, real-time structure recognition is provided by utilizing an augmented reality technology, an intelligent navigation strategy is generated by pre-training a reinforcement learning model, an instrument control system with multilayer safety guarantee is established, and continuous optimization of the system is realized by adopting an online learning mechanism. According to the invention, the precision and safety of the operation are effectively improved, and an effective technical scheme is provided for intelligent navigation control of the cataract operation.

The invention provides a fundus image enhancement method based on adaptive fuzzy evaluation and frequency domain enhancement, and the method comprises the following steps: S1, obtaining cataract fundus image samples of different fuzzy levels, and constructing a training data set; s2, constructing an image adaptive enhancement model based on fuzzy evaluation, wherein the image adaptive enhancement model comprises a fuzzy evaluation module, a consistency keeping module and a frequency adaptive enhancement module; and S3, performing model training on the constructed image adaptive enhancement model by using the training data set to obtain a trained image adaptive enhancement model which is used for adaptive enhancement of the cataract eye fundus image. According to the method, the structural definition and color fidelity of the cataract blurred fundus image can be effectively improved, and the diagnosis availability and clinical value of the image are improved.

The invention discloses a cataract fundus image automatic grading method based on semi-supervised learning, and belongs to the field of medical artificial intelligence. Characteristic parameters are extracted through multi-modal feature fusion of the eye fundus image of a patient, a semi-supervised learning neural network model is constructed, a pseudo-label training model is formed in combination with a small amount of labeled data and a large amount of unlabeled data, automatic classification of the eye fundus image of cataract is realized, and the problems of low manual classification efficiency and high labeled data acquisition cost are solved. In the preprocessing stage, texture and color multi-dimensional feature parameters of an image are extracted, and image data are obtained through dimension reduction. In the model construction stage, network training data of double convolution activation layers and double maximum pooling layers are adopted, and the model outputs all levels of probabilities to realize grading. The semi-supervised iterative training adopts a pseudo tag generation and model optimization alternating strategy, and a high-confidence sample expansion training set is screened. In the evaluation stage, the performance of the model is comprehensively measured by using multiple indexes and a visualization technology, and finally the model is deployed and applied to provide reliable support for clinical diagnosis.

The invention discloses a dioptric scleroderma cataract dynamic intraocular pressure stable control ultrasonic emulsification system adaptive to a dual-channel operation, which comprises a host control unit, an ultrasonic emulsification handle, a perfusion and suction system, an intraocular pressure monitoring unit, a pressure balance module and a scleroderma fragmentation module, through cooperation of the intraocular pressure control module and the two-way operation type adaptive control module, a high-precision filling valve and a closed-loop suction pump are synchronously adjusted in real time according to anterior chamber built-in and external monitoring fusion data, and intraoperative intraocular pressure fluctuation is controlled within + / -2 mmHg; through pulse modulation and a self-adaptive negative pressure curve of the hardcore fragmentation enhancement module, the stability of the anterior chamber is ensured while the hardcore fragmentation efficiency is improved; fluid dynamics and energy parameters can be automatically optimized according to conventional incisions or micro incisions; according to the system, the anterior chamber stability problem in the high-difficulty cataract surgery is solved.

The invention discloses a continuous optical zoom slit-lamp microscope system and an inspection method and application thereof, and belongs to the technical field of ophthalmology medical equipment. The system is composed of a continuous zooming module, a light source module, a data processing module, a 3D imaging module and an AI identification module. The inspection method comprises the steps of equipment initialization and head position fixation of an inspected person, AI low-magnification (5 *) preliminary screening, adaptive lens high-magnification (40 *) fine observation, dynamic light source adjustment, three-dimensional data acquisition and cloud intelligent diagnosis. The method is applied to examination and intelligent diagnosis of eye diseases such as cataract. The problems that a traditional slit-lamp microscope is discontinuous in zooming, inconvenient to operate, lack of intelligent diagnosis and free of 3D stereoscopic display are solved, and the objective of the invention is to realize simple and convenient equipment operation, continuous examination process, intelligent diagnosis and stereoscopic display, facilitate collective teaching, significantly improve the diagnosis efficiency and accuracy of eye diseases such as cataract and the like, and improve the diagnosis efficiency and accuracy of eye diseases such as cataract and the like. And DICOM standard data cloud sharing and remote consultation are supported.

The application discloses an ophthalmic disease image classification system based on a big data model, which comprises a data set construction module, an image segmentation module and a model training module.The data set construction module is used for collecting eye images of patients with different ophthalmic diseases in an ophthalmic clinic and performing image marking processing to construct training and test data sets.The image segmentation module adopts YOLOv7 to perform image segmentation on the images taken by the smart phone to obtain eye images containing only the part below the eyebrows and above the zygomatic arch.The model training module adopts a five-fold cross-validation method to train the model on the images, and applies data enhancement technology, white balance adjustment and a transfer learning algorithm.The application relates to the technical field of ophthalmic disease image classification.The ophthalmic disease image classification system based on the big data model has high classification accuracy for diseases such as cataracts, keratitis and pterygium in the development stage test set and different clinical evaluation stages.

The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative. The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative thereof, for use in a method for the treatment of conjunctivitis and for the prevention or treatment of inflammation or prevention of infection after cataract surgery in a subject, according to a dosage regimen that improves patient compliance and tolerability and enables the prevention and treatment of intermediate / antibiotic-resistant infections.

A method for collecting biometric measurement data of an eye on the basis of different measurement modalities, allowing for physiologically correct, representative, and robust biometric measurement data. In the method, the measurement data for individual measurement variables and the dynamic behavior of the eye are recorded continuously at the highest possible repetition rate over the measurement time. The individual phases of the dynamics of the eye which define the limits of the phase for stable vision are analyzed on the basis of the measurement values, and only the measurement data for the individual measurement variables are output which have been detected during the phase for stable vision. Although the proposed method is provided for collecting biometric measurement data in preparation for a cataract operation, the method can also be applied to other areas of ophthalmology to generate error-free measurement data or recordings of the eye.

There is provided a method for determining type of cataract by an electronic device. The method includes performing vision focus calibration for a user, determining central and peripheral regions of interest on a display of the electronic device based on fixated vision, performing a primary test for obtaining scores for the central and peripheral regions of interest, selecting at least one vision test mode based on the obtained score, and adapting at least one visual display parameter based on the obtained score and the selected at least one vision test mode. The method also includes determining a type of cataract from the selected at least one vision test mode, determining severity of the determined type of cataract, and providing the determined type of cataract and the determined severity with one or more recommendations to the user.

The application discloses an STM2457-PLGA nano drug, an artificial lens and a preparation method and application thereof, and relates to the technical field of biological medicine. The preparation method of the STM2457-PLGA nano drug comprises the following steps: preparing nano microspheres by injecting an oil phase comprising STM2457 and PLGA and a water phase comprising PVA into a microfluidic chip, and obtaining the STM2457-PLGA nano drug after freeze-drying of the nano microspheres, wherein the particle size of the STM2457-PLGA nano drug is 50-300 nm. The long-acting release of STM2457 carried by the surface-modified artificial lens is realized through the controlled release effect of the PLGA nano microspheres, and the slow-release period can cover the high-incidence period of postoperative complications of cataract surgery through process optimization, far exceeding the traditional short-term release system, and can continuously meet the long-term prevention and treatment needs after surgery, and effectively reduce the risk of complications such as after-cataract.

Devices and methods for replacing a human lens after cataract surgery. The device is an insert for the eye capsule and is formed of two or more rings that are connected to one another. A primary lens is affixed to the insert. A secondary add-in lens can be added to the insert in a subsequent surgery to correct, or further optimise, the optical results obtained with the initial surgery.

Pharmaceutical compositions, methods for treating various issues of the eyes, and methods of preparing such compositions are described. These pharmaceutical compositions may be for treating glaucoma, in preparation of eye surgery, during eye surgery, various post-op care (e.g., after cataract surgery, laser eye surgery, and the like), for treating dry eyes, and / or for promoting eyelash growth. These pharmaceutical compositions may comprise such active ingredients (APIs) as: timolol, latanoprost, brimonidine tartrate, dorzolamide, moxifloxacin HCl, dexamethasone PO4, phenylephrine HCl, lidocaine HCl, ketorolac tromethamine, bromfenac, prednisolone PO4, gatifloxacin, amniotic cytokine extract (ACE), prostaglandin E2 (PGE2), and combinations thereof.

A noninvasive ophthalmic formulation, comprising a chelator (such as EDTA and its salts), a transport enhancer (such as Methyl Sulfonyl Methane; MSM), a second polyoxyalkylene permeation enhancer such as propylene glycol capable of enhancing permeation through lipid-thickened ocular membranes, a thickening agent such as hydroxyethyl cellulose (HEC) and a surfactant such as polysorbate 80, is provided. The novel combination of the ingredients unexpectedly and beneficially reduces symptoms associated with early-stage, age-related cataracts. Methods for treating cataracts with compositions of the invention and measurement of improved visual function by measuring contrast sensitivity (CS) are provided.

The multifocal intraocular lens 100 includes a first arm 105, a second arm 110 and an optic 115. The lens 100 is positioned on the pupil 120 instead of the cataractous natural lens of the eye. The optic 115 of the lens 100 has three different zones, each zone is defined with different degrees as per the user's requirement. The first zone 125 provide distance vision, the second zone 130 provides intermediate vision and the third zone 135 provides near vision. The zones defined on the optic 115 are adaptable to contraction and expansion of the pupil 120 and provide clear vision in both said states of the pupil 120.

The utility model relates to a device for assisting in improving negative pressure to quickly suck and remove broken nucleus of cataract, which comprises a suction head, a filter tube body, a filter screen and a flow limiting element, the inlet end of the front end of the filter tube body is connected with the suction head, and the outlet end of the rear end of the filter tube body is connected with a negative pressure suction device. A flow limiting element is further arranged between the outlet end of the rear end of the filter pipe body and the negative pressure suction device, and a filter screen is installed in the filter pipe body. The aperture of a single hole of the filter screen is smaller than the inner diameter of the flow-limiting element, and the inner diameter of the suction head is larger than that of the flow-limiting element. The device has the advantages that the flow limiting element is designed and mounted on the rear side of the suction head, and the inner diameter of the suction head is larger than that of the flow limiting element, so that the problems that the anterior chamber in the eyeball is unstable, shallower, disappears and the like under the condition of overhigh negative pressure can be prevented, and the operation is safe and reliable; meanwhile, the filter screen is designed on the filter pipe body, and the pore diameter of the filter screen is smaller than the inner diameter of the flow limiting element, so that broken nuclei are filtered and collected, and the problem of low negative pressure suction efficiency caused by blockage of the flow limiting element by overlarge broken nuclei is prevented.

The present application relates to the technical field of medicine and provides a lanosterol derivative, a preparation method therefor and a use thereof. The structural formula of the lanosterol derivative provided by the present application is as shown in formula I or II. The lanosterol derivative provided by the present application has both lipid solubility and water solubility, and can effectively penetrate into the pathological site in the body, thereby improving the drug utilization rate. The results of embodiments show that the lanosterol derivative provided by the present application has a significantly higher solubility in water than lanosterol or 25-hydroxylanosterol and shows a significant therapeutic effect on a cataract in animal in vivo experiments. Therefore, the derivative has wide prospects in the preparation of drugs for treating eye diseases or conditions.

Cataract surgery is in recent years more and more augmented and supported by the application of laser cuts in the eye tissue. Such laser systems are separate units from the phacoemulsification system units that are usually used for cataract extraction. The laser systems require the patient to be positioned under the laser unit and then being moved under the surgical microscope next to the phacoemulsification unit. The here described invention relates to systems combining several aspects of the laser system and the phacoemulsification system. In particular, this invention relates to combining at least some parts of the control system and the housing for both systems and thereby minimizing and optimizing setup time, operating room footprint, patient flow and cost. Furthermore the here disclosed invention relates to integrating the laser system under the surgical microscope and thereby significantly reducing the surgery setup and complexity.

The present invention relates to an ocular formulation intended for the treatment of dry eyes and cataracts. The ocular formulation, particularly in the form of eye drop and in-situ gel, comprising gallic acid and quercetin. The invention further describes the method of preparation of ocular formulation.

The utility model discloses a kind of cataract surgery tear capsule auxiliary devices, including vertically arranged U-shaped seat, U-shaped seat is connected in one side of two movable seats by drive assembly, movable seat is fixedly connected in one end of long rod, the other end of long rod is screw-connected with the first screw rod perpendicular to long rod, the one end of first screw rod is equipped with first knob, the other end of first screw rod is equipped with annular groove, the both sides of U-shaped seat are equipped with corresponding connecting block, connecting block is fixed to patient face by corresponding bandage, this kind of cataract surgery tear capsule auxiliary device uses, first, by bandage, the whole is fixed to patient face, then by drive assembly, two movable seats drive corresponding first screw rod in opposite or opposite direction synchronous movement, to tear open by two first screw rods respectively to upper eyelid and lower eyelid, annular groove is equipped on first screw rod, support eyelid by annular groove, it is convenient to tear capsule to eyeball.

The utility model discloses an improved capsular bag tension section which comprises a main body ring, the whole main body ring is in an arc shape, the span of a main body is 120 degrees, clamping positioning holes are formed in the two ends of the main body ring, the main body ring and the clamping positioning holes are connected in a smooth transition mode, and a sclera fixing hook is arranged on the inner side of the middle of the main body ring. According to the utility model, fixed support can be realized in a small-range area of the capsular bag, permanent support can be realized through sclera suture, a plurality of capsular bag tension sections can be used in the same capsular bag when necessary, and when circumferential support is needed, the capsular bag tension sections can be combined with a capsular bag tension ring for use, so that the use is convenient. According to the utility model, 360-degree expansive force cannot be generated, the device can be used for suspension ligament fracture in a larger range, the stable capsular bag can be used before cataract ultrasonic emulsification, the tension section of the capsular bag can be implanted after a crystalline lens is sucked away, and the device is particularly suitable for children with small capsular bag diameter and incomplete dislocation of crystalline lens or small spherical crystalline lens patients.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition, a preparation method thereof and application of the traditional Chinese medicine composition in preparation of medicines for treating ophthalmic diseases. The traditional Chinese medicine composition provided by the invention is prepared from the following raw materials: flos chrysanthemi, concha haliotidis, semen cassiae torae, honey-fried licorice root and a component A, wherein the component A is selected from at least one of herba schizonepetae, radix puerariae and herba menthae. The composition has the effects of removing heat from the liver and purging heat, and treating red and astringent eye pain, and experiments show that the composition can improve the tear secretion amount, prolong the tear film rupture time and / or protect the corneal epithelium. The traditional Chinese medicine composition can be clinically used for treating dry eyes, asthenopia, keratoconjunctivitis, cataract and vitreous opacity.

The present application relates to the technical field of medicine, and provides a lanosterol derivative, a preparation method and application thereof.The structural formula of the lanosterol derivative provided by the present application is shown as formula I or formula II.The lanosterol derivative provided by the present application has both fat solubility and water solubility, can effectively penetrate into the pathological site in the body, and improves the drug utilization degree;the results of examples show that the solubility of the lanosterol derivative provided by the present application in water is obviously higher than that of lanosterol or 25-hydroxy lanosterol, and the lanosterol derivative shows obvious cataract treatment effect in animal body experiments, and has a broad prospect in the preparation of drugs for treating eye diseases or conditions.

The invention provides an electric capsulorhexis knife for a cataract capsulorhexis operation and an operation method of the electric capsulorhexis knife, and relates to the field of cataract capsulorhexis. The device comprises a handle, the using end of the handle is fixedly connected with a connecting rod; the other end of the connecting rod is fixedly connected with an extending rod; a rotating device is arranged on the surface of the lower side of the extending rod and located at the end; a cutting device is arranged at the end of the rotating device and located on the lower side surface of the stretching-in rod. The inner side wall of the handle is slidably connected with a clamping device; and a control button is arranged on the inner side surface of the handle. Through the arrangement of a clamping device, a clamping block and a silica gel cover, the clamping of the clamping block is controlled by the clamping device, so that the torn front capsule film is conveniently taken out, the efficiency of taking out the front capsule film is improved, and the radius length of the torn film is adjusted through the arrangement of a rotating rod, an adjusting device and a cutting device in a rotating device; meanwhile, the cutting depth of the anterior capsular membrane is adjusted to prevent the internal posterior capsular membrane from being damaged.

A cataract classification method based on color equivariant and frequency domain attention belongs to the technical field of computer vision and medical artificial intelligence, uses eye images shot by a slit lamp as an input data source, and constructs a CFC-Mama classification network integrated with a color equivariant fusion module and a frequency domain channel attention module to classify cataracts. The model can effectively extract color robust features with unchanged equipment, and the high-frequency detail perception capability of the cataract lesion boundary is enhanced; a color isotropic convolution and cross attention fusion mechanism is adopted to solve the color shift problem caused by different imaging devices, and the cross-device robustness of feature extraction is ensured; through a frequency domain channel attention module, in combination with Fourier transform, high-pass filtering and a double-path channel attention strategy, high-frequency features of lesion boundaries are highlighted, and the fine-grained feature expression ability is improved. The invention further provides a cataract classification system based on color equivariant and frequency domain attention. According to the invention, high-precision classification of multi-granularity cataract is realized.

The invention discloses an intelligent head bracket for ophthalmologic operation. The intelligent head bracket comprises a mounting frame, a positioning rod, a head frame adapter, a bracket body, a head supporting tray, an air pressure type lifting assembly, an adjusting structure and a head fixing structure. Through cooperation of a separated expansion structure and a press-fit closed structure, intelligent distribution of air paths is achieved with the dead weight of the head of a patient as a control signal, the air paths in a pressed area are closed to form a firm bearing face, and the air paths in an unpressed neck area are smooth; by combining a multi-cavity independent fine adjustment structure, a multi-dimensional angle adjustment system and a mechanical locking type head fixing structure, personalized supporting of the head and the neck, fine hardness adjustment in an operation, multi-dimensional body position adjustment and reliable fixing are achieved. The head fixing device can adapt to patients with different head shapes / neck lengths without an electronic sensor, is high in supporting stability and good in comfort, does not interrupt the operation process during operation adjustment, and provides a reliable head fixing solution for high-precision ophthalmologic operations such as cataract and vitrectomy.

The present invention relates to a novel refractive intraocular lens (IOL) having a continuous range of view, extended depth of field (EDOF), capable of providing a continuous clear field of view for cataract patients when objects from far to near while minimizing halo and glare phenomena. The novel refractive EDOF continuous visual range artificial lens provided by the invention has the advantage that the extended focal depth can be provided, so that a patient can obtain continuous vision from a far position to a near position (35-40cm). The spherical aberration of each area on the front surface of the artificial lens is optimized, halo and glare are reduced to the maximum extent, the 60-degree refraction section of the fourth area is used for providing balanced energy distribution when the pupil diameter is large, the pupil is irrelevant to magnification distribution, and the lens magnification and the extension focal depth are not affected by the pupil size or light conditions. The partition modification of the intraocular lens can be used as a controllable switch, and the focal depth can be adjusted according to requirements, namely, the focal depth is adjusted from a far vision field to a near vision field or from the far vision field to a middle vision field.

The application discloses a pre-cataract surgery visual function expectation evaluation method, collects preoperative basic examination data, subjective expectation expression data and a preset visual task scene library, and screens a candidate visual task scene set; a scene acceptance result set is obtained through patient acceptance interaction discrimination; subjective expectation expression data are combined and analyzed to generate a visual function requirement parameter set; a visual task tolerance threshold is further quantified and structured and coded into an expectation feature vector, and a preoperative visual function expectation evaluation result is output, which is used for preoperative lens matching, preoperative communication prompting or postoperative satisfaction risk prediction.

FIELD: ophthalmology.SUBSTANCE: used to remove residual cortical masses that have migrated to the equatorial region after cataract extraction (CE) in patients after keratoprosthetics. To do this, the optical cylinder of the keratoprosthesis is unscrewed using a key. Residual cortical masses are visualized through the opening of the optical cylinder (OOC) and removed using a Simcoe cannula or a straight cannula with a flat tip mounted on a 10 ml syringe. The optical cylinder is screwed back in using a key.EFFECT: invention reduces the risk of developing intra- and postoperative complications and accelerates visual rehabilitation of patients by reducing the time of surgical intervention and without performing additional approaches.1 cl, 1 ex

This application discloses a method for detecting corneal thickness after phacoemulsification cataract surgery based on anterior segment OCT, belonging to the field of image analysis technology. The method includes: dividing the cornea into multiple first regions based on a region growing algorithm and initial corneal thickness data; obtaining second regions based on each first region; obtaining multiple partial boundaries based on the second regions; obtaining fibrotic regions based on each partial boundary; and adjusting the scanning density and refractive index of the second regions based on the fibrotic regions and a scanning density correction coefficient to obtain the final corneal thickness data. This application combines the fibrotic regions and the scanning density correction coefficient to adjust the scanning density and refractive index of the second regions, avoiding the errors of calculations using a uniform refractive index in existing technologies, ultimately achieving accurate measurement of corneal thickness and solving the technical problem that existing OCT detection cannot accurately measure corneal regional thickness.

The invention belongs to the technical field of ophthalmologic surgical instruments, and provides a posterior capsular membrane polisher in a cataract surgery in order to solve the problem that existing manual operation is low in accuracy. Comprising a head fixing module for fixing the head of a patient; the movable positioning module is arranged on the head fixing module and comprises up-down telescopic assemblies arranged on the two sides of the head fixing module, a longitudinal moving assembly and a transverse moving assembly are arranged on the up-down telescopic assemblies, and a polishing module mounting frame is arranged on the transverse moving assembly; the polishing head multifunctional integrated module comprises a supporting frame connected through a polishing module mounting frame, the supporting frame is provided with an eye periphery supporting rod and a micro-pressure induction push rod, the micro-pressure induction push rod is connected with a connecting plate, the connecting plate is connected with a polishing rod, and a polishing head is arranged in the polishing rod. By means of the integrated design, it can be guaranteed that the operation is completed through one-time polishing operation, errors caused by manual operation are avoided, previous tedious steps are omitted, the operation time is shortened, and the operation risk is reduced.