207 results about "Cataracts" patented technology

The invention relates to the technical field of intelligent medical treatment, and discloses a cataract surgery navigation control method based on multi-modal fusion, which comprises the following steps: carrying out lightweight preprocessing on an eye fundus image, ultrasonic probe data, a corneal topographic map and intraocular pressure parameters through an edge computing architecture, and constructing an efficient feature extraction network by adopting a knowledge distillation technology; self-adaptive feature fusion is realized based on an uncertainty quantification mechanism, real-time structure recognition is provided by utilizing an augmented reality technology, an intelligent navigation strategy is generated by pre-training a reinforcement learning model, an instrument control system with multilayer safety guarantee is established, and continuous optimization of the system is realized by adopting an online learning mechanism. According to the invention, the precision and safety of the operation are effectively improved, and an effective technical scheme is provided for intelligent navigation control of the cataract operation.

The invention provides a fundus image enhancement method based on adaptive fuzzy evaluation and frequency domain enhancement, and the method comprises the following steps: S1, obtaining cataract fundus image samples of different fuzzy levels, and constructing a training data set; s2, constructing an image adaptive enhancement model based on fuzzy evaluation, wherein the image adaptive enhancement model comprises a fuzzy evaluation module, a consistency keeping module and a frequency adaptive enhancement module; and S3, performing model training on the constructed image adaptive enhancement model by using the training data set to obtain a trained image adaptive enhancement model which is used for adaptive enhancement of the cataract eye fundus image. According to the method, the structural definition and color fidelity of the cataract blurred fundus image can be effectively improved, and the diagnosis availability and clinical value of the image are improved.

The invention relates to the field of surgical robots, and particularly discloses an intraoperative risk assessment system for a cataract surgical robot, comprising: a patient biomechanical monitoring unit for collecting a contact force between an instrument and an eye tissue, and calculating an anterior chamber equivalent pressure value according to an axial force component of the contact force and a contact area between the instrument and a cornea; the patient optical imaging monitoring unit is used for collecting microstructure images of the cornea and the lens capsule and quantifying the energy release density of ultrasonic emulsification; the robot motion parameter monitoring unit is used for collecting joint motion resistance, instrument tail end three-dimensional coordinates, motion speed and attitude angle of the robot; the multi-mode joint reasoning unit is used for identifying a high-risk operation state when the contact force is higher than a first preset value and the energy release density is higher than a second preset value; by adopting the technical scheme of the invention, multi-dimensional real-time monitoring can be realized, and a dynamic risk prediction model can be established by fusing heterogeneous data through an intelligent algorithm.

The invention discloses a cataract fundus image automatic grading method based on semi-supervised learning, and belongs to the field of medical artificial intelligence. Characteristic parameters are extracted through multi-modal feature fusion of the eye fundus image of a patient, a semi-supervised learning neural network model is constructed, a pseudo-label training model is formed in combination with a small amount of labeled data and a large amount of unlabeled data, automatic classification of the eye fundus image of cataract is realized, and the problems of low manual classification efficiency and high labeled data acquisition cost are solved. In the preprocessing stage, texture and color multi-dimensional feature parameters of an image are extracted, and image data are obtained through dimension reduction. In the model construction stage, network training data of double convolution activation layers and double maximum pooling layers are adopted, and the model outputs all levels of probabilities to realize grading. The semi-supervised iterative training adopts a pseudo tag generation and model optimization alternating strategy, and a high-confidence sample expansion training set is screened. In the evaluation stage, the performance of the model is comprehensively measured by using multiple indexes and a visualization technology, and finally the model is deployed and applied to provide reliable support for clinical diagnosis.

The invention discloses a dioptric scleroderma cataract dynamic intraocular pressure stable control ultrasonic emulsification system adaptive to a dual-channel operation, which comprises a host control unit, an ultrasonic emulsification handle, a perfusion and suction system, an intraocular pressure monitoring unit, a pressure balance module and a scleroderma fragmentation module, through cooperation of the intraocular pressure control module and the two-way operation type adaptive control module, a high-precision filling valve and a closed-loop suction pump are synchronously adjusted in real time according to anterior chamber built-in and external monitoring fusion data, and intraoperative intraocular pressure fluctuation is controlled within + / -2 mmHg; through pulse modulation and a self-adaptive negative pressure curve of the hardcore fragmentation enhancement module, the stability of the anterior chamber is ensured while the hardcore fragmentation efficiency is improved; fluid dynamics and energy parameters can be automatically optimized according to conventional incisions or micro incisions; according to the system, the anterior chamber stability problem in the high-difficulty cataract surgery is solved.

The invention discloses a continuous optical zoom slit-lamp microscope system and an inspection method and application thereof, and belongs to the technical field of ophthalmology medical equipment. The system is composed of a continuous zooming module, a light source module, a data processing module, a 3D imaging module and an AI identification module. The inspection method comprises the steps of equipment initialization and head position fixation of an inspected person, AI low-magnification (5 *) preliminary screening, adaptive lens high-magnification (40 *) fine observation, dynamic light source adjustment, three-dimensional data acquisition and cloud intelligent diagnosis. The method is applied to examination and intelligent diagnosis of eye diseases such as cataract. The problems that a traditional slit-lamp microscope is discontinuous in zooming, inconvenient to operate, lack of intelligent diagnosis and free of 3D stereoscopic display are solved, and the objective of the invention is to realize simple and convenient equipment operation, continuous examination process, intelligent diagnosis and stereoscopic display, facilitate collective teaching, significantly improve the diagnosis efficiency and accuracy of eye diseases such as cataract and the like, and improve the diagnosis efficiency and accuracy of eye diseases such as cataract and the like. And DICOM standard data cloud sharing and remote consultation are supported.

Systems, devices and methods are provided that provide assistance in selecting appropriate interventions for treatment of disease and injury to the eye. Systems of the inventive concept provide cloud-based processing and storage of clinical and patient-specific data, which can provide treatment recommendations and projected outcomes to a practitioner using a local device. Systems, devices, and methods can generate interactive physiomechanical models of the eye of a specified individual, which are derived measurements of mechanical properties of structures of the eye. The physiomechanical model is interactive, and can be used to emulate the effects of one or more medical interventions in the eye in order to implement an optimized treatment plan for the individual.

The invention discloses a lens anterior-posterior capsule polisher, which is characterized in that a cleaning part is communicated with a pipeline part to form an integrated instrument. One part of the surface of the cleaning part is provided with a frosted part, and the other part of the surface is provided with a plurality of through holes. The frosted part can polish the anterior lens capsule by utilizing friction force, residual lens cortex and epithelial cells are removed, the postoperative lens capsular bag contraction probability is reduced, and the stability of the intraocular lens and the postoperative vision durability are enhanced. The through hole is matched with the pipeline part, and when the free end of the pipeline part is connected with intraocular perfusate, the perfusate can be sprayed through the through hole in multiple angles and multiple directions to wash and polish the posterior capsule. Compared with a bald needle head used in an existing water polishing technology, the polisher is wider and more uniform in flushing, operation safety can be effectively improved, postoperative vision and visual quality are improved, and the occurrence rate of posterior cataract is reduced. By means of the design, front and rear capsule membranes are polished through a single instrument, frequent instrument replacement in an operation is avoided, operation steps are simplified, and the operation effect and safety are improved.

The invention provides an intelligent follow-up visit monitoring system after cataract operation, and relates to the technical field of image processing. The intelligent follow-up visit monitoring system after the cataract operation comprises an acquisition module used for acquiring a plurality of image samples after the cataract operation; the classification module is used for inputting the plurality of image samples into a pre-trained image classification model and outputting probability values of classification results of various complications after the cataract operation corresponding to the image samples; the determining module is used for determining the uncertain value of each image sample according to the probability value of the classification result of various complications after the cataract operation corresponding to each image sample; the screening module is used for screening out a target image sample according to the uncertain value of each image sample; and the training module is used for training an image classification model according to the target image sample and the labeling result of the target image sample, and the trained image classification model is used for assisting in determining a post-cataract follow-up visit scheme. The method can improve the follow-up visit efficiency after the cataract operation.

The application discloses an ophthalmic disease image classification system based on a big data model, which comprises a data set construction module, an image segmentation module and a model training module.The data set construction module is used for collecting eye images of patients with different ophthalmic diseases in an ophthalmic clinic and performing image marking processing to construct training and test data sets.The image segmentation module adopts YOLOv7 to perform image segmentation on the images taken by the smart phone to obtain eye images containing only the part below the eyebrows and above the zygomatic arch.The model training module adopts a five-fold cross-validation method to train the model on the images, and applies data enhancement technology, white balance adjustment and a transfer learning algorithm.The application relates to the technical field of ophthalmic disease image classification.The ophthalmic disease image classification system based on the big data model has high classification accuracy for diseases such as cataracts, keratitis and pterygium in the development stage test set and different clinical evaluation stages.

The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative. The present invention relates to an ophthalmic composition in the form of an aqueous solution containing levofloxacin or salt or derivative thereof and ketorolac or salt or derivative thereof, for use in a method for the treatment of conjunctivitis and for the prevention or treatment of inflammation or prevention of infection after cataract surgery in a subject, according to a dosage regimen that improves patient compliance and tolerability and enables the prevention and treatment of intermediate / antibiotic-resistant infections.

A method for collecting biometric measurement data of an eye on the basis of different measurement modalities, allowing for physiologically correct, representative, and robust biometric measurement data. In the method, the measurement data for individual measurement variables and the dynamic behavior of the eye are recorded continuously at the highest possible repetition rate over the measurement time. The individual phases of the dynamics of the eye which define the limits of the phase for stable vision are analyzed on the basis of the measurement values, and only the measurement data for the individual measurement variables are output which have been detected during the phase for stable vision. Although the proposed method is provided for collecting biometric measurement data in preparation for a cataract operation, the method can also be applied to other areas of ophthalmology to generate error-free measurement data or recordings of the eye.

There is provided a method for determining type of cataract by an electronic device. The method includes performing vision focus calibration for a user, determining central and peripheral regions of interest on a display of the electronic device based on fixated vision, performing a primary test for obtaining scores for the central and peripheral regions of interest, selecting at least one vision test mode based on the obtained score, and adapting at least one visual display parameter based on the obtained score and the selected at least one vision test mode. The method also includes determining a type of cataract from the selected at least one vision test mode, determining severity of the determined type of cataract, and providing the determined type of cataract and the determined severity with one or more recommendations to the user.

Provided is a polypeptide capable of dissolving protein aggregates. Also provided is a method of treating a phase separation associated diseases, such as phase separation associated visual disorders (e.g., cataracts) using the polypeptide provided herein.

The application discloses an STM2457-PLGA nano drug, an artificial lens and a preparation method and application thereof, and relates to the technical field of biological medicine. The preparation method of the STM2457-PLGA nano drug comprises the following steps: preparing nano microspheres by injecting an oil phase comprising STM2457 and PLGA and a water phase comprising PVA into a microfluidic chip, and obtaining the STM2457-PLGA nano drug after freeze-drying of the nano microspheres, wherein the particle size of the STM2457-PLGA nano drug is 50-300 nm. The long-acting release of STM2457 carried by the surface-modified artificial lens is realized through the controlled release effect of the PLGA nano microspheres, and the slow-release period can cover the high-incidence period of postoperative complications of cataract surgery through process optimization, far exceeding the traditional short-term release system, and can continuously meet the long-term prevention and treatment needs after surgery, and effectively reduce the risk of complications such as after-cataract.

Devices and methods for replacing a human lens after cataract surgery. The device is an insert for the eye capsule and is formed of two or more rings that are connected to one another. A primary lens is affixed to the insert. A secondary add-in lens can be added to the insert in a subsequent surgery to correct, or further optimise, the optical results obtained with the initial surgery.

The invention aims at providing a device for facilitating cornea wetting in cataract surgery, and relates to the technical field of medical instruments, an infusion assembly and an eyelid opening assembly are installed on a support, a water dripping rod is installed on an eyelid opening device of the eyelid opening assembly, and a doctor does not need to hold the device for dripping water by hand; the control panel is arranged on the bracket, so that the running power of the infusion pump, the on-off of the infusion pump and the timing working time of the infusion pump can be controlled flexibly to control the water flow speed of the point water and the timing point water so as to ensure that the cornea is always in an ideal wet state; the distance between the eye speculum on the two sides of the fixed part and the eye speculum on the two sides of the movable part can be adjusted through stretching of the fixed telescopic rod of the fixed part, and therefore the distance between the upper eyelid and the lower eyelid is controlled. The distance between the eye speculum bodies on the two sides of the movable part can be further adjusted by rotating the side screw rods of the movable part, and therefore different opening space shapes are met; the distance between the eye speculum of the movable part and the eye speculum of the fixed part can be adjusted by rotating the movable screw rod, so that the size of the expanded space is adjusted.

Pharmaceutical compositions, methods for treating various issues of the eyes, and methods of preparing such compositions are described. These pharmaceutical compositions may be for treating glaucoma, in preparation of eye surgery, during eye surgery, various post-op care (e.g., after cataract surgery, laser eye surgery, and the like), for treating dry eyes, and / or for promoting eyelash growth. These pharmaceutical compositions may comprise such active ingredients (APIs) as: timolol, latanoprost, brimonidine tartrate, dorzolamide, moxifloxacin HCl, dexamethasone PO4, phenylephrine HCl, lidocaine HCl, ketorolac tromethamine, bromfenac, prednisolone PO4, gatifloxacin, amniotic cytokine extract (ACE), prostaglandin E2 (PGE2), and combinations thereof.

A noninvasive ophthalmic formulation, comprising a chelator (such as EDTA and its salts), a transport enhancer (such as Methyl Sulfonyl Methane; MSM), a second polyoxyalkylene permeation enhancer such as propylene glycol capable of enhancing permeation through lipid-thickened ocular membranes, a thickening agent such as hydroxyethyl cellulose (HEC) and a surfactant such as polysorbate 80, is provided. The novel combination of the ingredients unexpectedly and beneficially reduces symptoms associated with early-stage, age-related cataracts. Methods for treating cataracts with compositions of the invention and measurement of improved visual function by measuring contrast sensitivity (CS) are provided.

The multifocal intraocular lens 100 includes a first arm 105, a second arm 110 and an optic 115. The lens 100 is positioned on the pupil 120 instead of the cataractous natural lens of the eye. The optic 115 of the lens 100 has three different zones, each zone is defined with different degrees as per the user's requirement. The first zone 125 provide distance vision, the second zone 130 provides intermediate vision and the third zone 135 provides near vision. The zones defined on the optic 115 are adaptable to contraction and expansion of the pupil 120 and provide clear vision in both said states of the pupil 120.

The utility model relates to a device for assisting in improving negative pressure to quickly suck and remove broken nucleus of cataract, which comprises a suction head, a filter tube body, a filter screen and a flow limiting element, the inlet end of the front end of the filter tube body is connected with the suction head, and the outlet end of the rear end of the filter tube body is connected with a negative pressure suction device. A flow limiting element is further arranged between the outlet end of the rear end of the filter pipe body and the negative pressure suction device, and a filter screen is installed in the filter pipe body. The aperture of a single hole of the filter screen is smaller than the inner diameter of the flow-limiting element, and the inner diameter of the suction head is larger than that of the flow-limiting element. The device has the advantages that the flow limiting element is designed and mounted on the rear side of the suction head, and the inner diameter of the suction head is larger than that of the flow limiting element, so that the problems that the anterior chamber in the eyeball is unstable, shallower, disappears and the like under the condition of overhigh negative pressure can be prevented, and the operation is safe and reliable; meanwhile, the filter screen is designed on the filter pipe body, and the pore diameter of the filter screen is smaller than the inner diameter of the flow limiting element, so that broken nuclei are filtered and collected, and the problem of low negative pressure suction efficiency caused by blockage of the flow limiting element by overlarge broken nuclei is prevented.

The application discloses an integrated imaging light field display method and device with cataract correction function, and the position and size of an eye turbidity area of a patient to be corrected are acquired; if the size of the eye turbidity area is less than or equal to a preset size, the position of the eye turbidity area is used to determine a target pixel position on a micro display, the light emitting unit at the target pixel position is turned off, and a corrected image is obtained; if the size is greater than the preset size, the position of a turbidity area with a large size is used to analyze the eye data after the light emitting unit at the target pixel position is turned off, the type of aberration of the patient to be corrected is obtained, a corresponding point spread function is determined according to the type of aberration, the Fourier transform of a blurred image is performed, a transformed image is obtained, the transformed image is corrected by using a corresponding correction function obtained by using the point spread function, and a corrected image is obtained. Through the above method, the correction accuracy of a cataract patient is improved.

1. The name of the design product: ultrasonic emulsification instrument for ophthalmology. 2. The use of the design product: used in ophthalmic operating room, the operation equipment for cataract lens core fragmentation, perfusion and suction and anterior segment vitrectomy and electrocoagulation. 3. The design points of the design product: in shape. 4. The picture or photo that can best show the design points: perspective view 1.

The invention belongs to the technical field of cataract crystal evaluation, and particularly relates to a cataract crystal turbidity degree quantitative evaluation method based on optical coherence tomography. OCT original data are calibrated through standard scatterer signals, the influence of equipment parameters and individual differences is eliminated, the objective comparability of physical quantities such as attenuation coefficients is ensured, and the accuracy of evaluation of the turbidity degree of a cataract crystal is improved. Subregions are accurately divided according to a crystal anatomical structure, attenuation coefficients of depth resolution and spatial texture features are synchronously extracted, limitation of single features is broken through, sensitive analysis of local opacity is realized, finally, multi-region and multi-dimensional parameters are automatically integrated by using a pre-trained feature fusion model, continuous comprehensive opacity quantitative indexes are generated, and the opacity analysis accuracy is improved. Dependence on artificial experience is completely avoided, and the sensitivity and repeatability of evaluation are remarkably improved; finally, closed-loop evaluation of calibration, regionalized decoding and intelligent quantization is formed.

This invention discloses an annular capsular bag for an intraocular lens (IOL), comprising a capsular body with a mitigation structure and a heparin coating. An IOL is implanted within this capsular body, and the IOL has a strip-shaped cap made of acrylic ester around its periphery. This invention uses the mitigation structure to block epithelial cells, preventing them from migrating towards the center of the IOL via the anterior and posterior surfaces, thus avoiding opacity in the central portion of the IOL and preventing vision loss, i.e., preventing secondary cataracts. Furthermore, the strip-shaped cap on the periphery of the IOL eliminates the need for additional fixation structures, simplifying the structure, reducing surgical steps, and accelerating the surgical process. Additionally, the heparin coating on the inner surface of the capsular body reduces the adhesion of the epithelial cells at the equatorial region of the annular capsular bag to the surface of the IOL, making them less prone to adhesion and facilitating subsequent IOL replacement.

The present application relates to the technical field of medicine and provides a lanosterol derivative, a preparation method therefor and a use thereof. The structural formula of the lanosterol derivative provided by the present application is as shown in formula I or II. The lanosterol derivative provided by the present application has both lipid solubility and water solubility, and can effectively penetrate into the pathological site in the body, thereby improving the drug utilization rate. The results of embodiments show that the lanosterol derivative provided by the present application has a significantly higher solubility in water than lanosterol or 25-hydroxylanosterol and shows a significant therapeutic effect on a cataract in animal in vivo experiments. Therefore, the derivative has wide prospects in the preparation of drugs for treating eye diseases or conditions.

Cataract surgery is in recent years more and more augmented and supported by the application of laser cuts in the eye tissue. Such laser systems are separate units from the phacoemulsification system units that are usually used for cataract extraction. The laser systems require the patient to be positioned under the laser unit and then being moved under the surgical microscope next to the phacoemulsification unit. The here described invention relates to systems combining several aspects of the laser system and the phacoemulsification system. In particular, this invention relates to combining at least some parts of the control system and the housing for both systems and thereby minimizing and optimizing setup time, operating room footprint, patient flow and cost. Furthermore the here disclosed invention relates to integrating the laser system under the surgical microscope and thereby significantly reducing the surgery setup and complexity.

An apparatus for aiding the removal of cataracts in which an optical fiber delivers sufficient optical energy of the correct wavelength, pulse duration to achieve controlled non-thermal and non-acoustic dissolution of hard cataract tissue.

The present invention relates to an ocular formulation intended for the treatment of dry eyes and cataracts. The ocular formulation, particularly in the form of eye drop and in-situ gel, comprising gallic acid and quercetin. The invention further describes the method of preparation of ocular formulation.

The utility model discloses a kind of cataract surgery tear capsule auxiliary devices, including vertically arranged U-shaped seat, U-shaped seat is connected in one side of two movable seats by drive assembly, movable seat is fixedly connected in one end of long rod, the other end of long rod is screw-connected with the first screw rod perpendicular to long rod, the one end of first screw rod is equipped with first knob, the other end of first screw rod is equipped with annular groove, the both sides of U-shaped seat are equipped with corresponding connecting block, connecting block is fixed to patient face by corresponding bandage, this kind of cataract surgery tear capsule auxiliary device uses, first, by bandage, the whole is fixed to patient face, then by drive assembly, two movable seats drive corresponding first screw rod in opposite or opposite direction synchronous movement, to tear open by two first screw rods respectively to upper eyelid and lower eyelid, annular groove is equipped on first screw rod, support eyelid by annular groove, it is convenient to tear capsule to eyeball.