7 results about "Chronic fatigue" patented technology

This invention discloses a chronic fatigue state monitoring system and method based on a state-space model, comprising a real-time perception layer and a longitudinal analysis layer. The real-time perception layer processes high-frequency raw data streams and outputs daily state vectors that quantify the user's overall fatigue state for the day. The high-frequency data streams include user facial video streams from an image sensor and computer event streams from a human-computer interaction device. The longitudinal analysis layer receives and processes long-term sequences composed of multiple daily state vectors, autonomously learns the user's fatigue accumulation and recovery patterns through end-to-end time-series analysis using a state-space model, and outputs predictive chronic fatigue risk monitoring results. This invention achieves end-to-end automated monitoring and prediction, from millisecond-level behavioral data acquisition to long-term health trend analysis, through the collaborative work of the real-time perception layer and the longitudinal analysis layer.

The invention provides a bifidobacterium longum and longan aril composition capable of synergistically relieving chronic fatigue, the bifidobacterium longum is named as BB36, the preservation number is CGMCC (China General Microbiological Culture Collection Center) NO.34123, and the preservation date is April 8, 2025. By improving the levels of stress hormones and neurotransmitters and reducing the serum inflammation level, the strain significantly improves the chronic fatigue symptom and improves the athletic ability; the invention further develops a bifidobacterium longum and longan aril composition capable of synergistically relieving chronic fatigue, and through compounding of probiotics and longan aril extract, it is found that the probiotics and the longan aril extract can cooperate with each other, and the composition has a synergistic effect in relieving chronic fatigue.

The invention discloses application of lactobacillus rhamnosus to preparation of a product for improving cognitive impairment or neuroinflammation caused by chronic fatigue. The lactobacillus rhamnosus BD4047 is an edible safety strain, and can improve cognitive impairment of a chronic fatigue animal model by reversing short-term spatial learning memory ability and working memory ability; by improving the indole level, lowering the IL-33 level and balancing intestinal flora, the neuroinflammation of a chronic fatigue animal model is relieved, so that the lactobacillus rhamnosus BD4047 can be used as an active ingredient for developing functional foods such as fermented milk, lactobacillus beverages, probiotic powder, viable bacteria water, milk powder and cheese, and has large-scale production and market popularization prospects.

The instant invention relates to the use of a substance with phosphodiesterase-7 inhibitory activity (PDE7 inhibitor) as active ingredient in a therapeutic agent with phosphodiesterase-7 inhibitory activity for the treatment and prevention of different diseases, syndromes, disease states, or conditions associated with chronic fatigue, exhaustion and / or exertional intolerance using PDE7 inhibitors alone or in combination with other therapeutic agents.

The instant invention relates to the use of a substance with phosphodiesterase-7 inhibitory activity (PDE7 inhibitor), such as spiro[[1,3]oxazolo[5,4f-]quinazoline-9,1′-cyclohexan)-7-one derivatives, as active ingredient in a therapeutic agent with phosphodiesterase-7 inhibitory activity for the treatment and prevention of different diseases, syndromes, disease states, or conditions associated with chronic fatigue, exhaustion and / or exertional intolerance using PDE7 inhibitors alone or in combination with other therapeutic agents.

The invention provides a medicine pillow for regulating mind, liver, spleen, lung and kidney based on the theory of five mind of traditional Chinese medicine, and comprehensive regulation of mind stabilization, liver soothing, spleen transformation, lung and kidney qi absorption is realized by implanting a traditional Chinese medicine composition and cooperating with acupoint stimulation. Through clinical verification, the effective rate on insomnia, anxiety and chronic fatigue is greater than 85%. The tea is beneficial to resuscitation and intelligence development, improves learning and memory, and has improvement effects on calming, convulsion resistance, depression resistance, arteriosclerosis resistance, hyperlipidemia resistance, hypertension and cardiovascular and cerebrovascular diseases.

This invention relates to a sports fatigue monitoring and management system and a sports fatigue monitoring and management method. Firstly, it provides a sports fatigue monitoring and management system, including an electronic fabric patch, a multimodal sensing module, and a data transmission and interaction module. The electronic fabric patch can be attached to the skin surface of a subject, and its electrode structure forms a multimodal sensing module capable of detecting flowing sweat or directly monitoring the subject's body. The electronic fabric patch uses porous fabric and gradient micropillar structures to dynamically regulate the accumulation of trace amounts of sweat and the drainage of excessive sweat, simultaneously collecting multidimensional physiological and biochemical indicators such as electromyographic signals, electrolytes, metabolites, and hormones. Additionally, an AI assessment module is deployed, based on a multi-algorithm fusion model trained using observation data during the rest-exercise-recovery process, to identify six types of fatigue-related states and generate intervention plans. In some embodiments, this can reduce fatigue levels by 51.82%, accelerate chronic fatigue recovery, and is suitable for athlete training monitoring and rehabilitation patient exercise management.