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200 results about "Bone healing" patented technology

Bone healing, or fracture healing, is a proliferative physiological process in which the body facilitates the repair of a bone fracture. Generally bone fracture treatment consists of a doctor reducing (pushing) displaced bones back into place via relocation with or without anaesthetic, stabilizing their position to aid union, and then waiting for the bone's natural healing process to occur.

Craniomaxillofacial dissimilar metal bone implant with antibacterial property and preparation method thereof

The invention discloses a cranio-maxillofacial dissimilar metal bone implant with an antibacterial property and a preparation method thereof, and relates to the technical field of medical implant prostheses, the preparation method comprises the following steps: step 1, preparing a nano-silver-antibacterial peptide GL13K composite peptide solution with the antibacterial property; 2, based on the selective laser melting technology, titanium alloy powder is prepared into a porous framework; 3, melting zinc powder, and filling pores of the porous skeleton with the molten zinc powder to obtain a semi-finished heterogeneous metal bone implant; step 4, depositing the nano-silver-antibacterial peptide GL13K composite peptide solution prepared in the step 1 on the surface of the semi-finished heterogeneous metal bone implant prepared in the step 3 through a pulse electrodeposition method to obtain a finished heterogeneous metal bone implant; the prepared finished heterogeneous metal bone implant has a remarkable antibacterial effect, the postoperative infection risk can be reduced, and the nano-silver-antibacterial peptide GL13K composite peptide can further promote osteoblast attachment and proliferation and accelerate the bone healing process.
Owner:JILIN UNIVERSITY

Modeling method and system for regulating and controlling bone healing through dynamic stress stimulation

The invention discloses a modeling method and system for regulating and controlling bone healing through dynamic stress stimulation, which are applied to the technical field of bone healing, and the method comprises the following steps: establishing a geometric model of a fracture part; performing mesh generation on the geometric model to generate finite element models of bones and callus; assigning values to the material attributes in the callus at the initial moment; applying dynamic load constraint to the top end of the cortical bone based on the finite element model, and establishing a bone healing model; calculating attributes of new materials in tissue cells, and judging whether the attributes of the new materials reach a preset healing standard or not through the bone healing model; if the preset healing standard is reached, simulation is completed, otherwise, iterative simulation is carried out by dynamically adjusting mechanical parameters until the preset healing standard is reached, and final bone healing data are output. Through the bone healing model, loading parameters are adjusted in real time according to simulation data, and the accuracy and reliability of bone healing simulation are improved.
Owner:SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Artificial intelligence auxiliary analysis system based on orthopedic images

The invention relates to the field of image processing, in particular to an artificial intelligence auxiliary analysis system based on orthopedic images, which comprises an image acquisition module, a grade determination module, a fracture detection module, a treatment detection module and a processing module. The fracture degree and the corresponding healing condition can be more accurately judged by comprehensively analyzing the initial bone image and the post-treatment bone image in combination with factors such as the age and the gender of a patient, the diagnosis accuracy is greatly improved, the bone healing rate is obtained by comparing the initial bone fracture proportion and the post-treatment bone fracture proportion, and the diagnosis accuracy is improved. Reliable data support is provided for evaluating the treatment effect, diagnosis and evaluation time can be greatly shortened, the overall treatment efficiency can be improved, whether the treatment effect is good or not is judged according to clinical data, suggestions about whether an operation needs to be conducted again or rehabilitation guidance needs to be given, the risk of human judgment errors can be reduced, and the treatment efficiency is improved. And the accuracy of diagnosis and treatment decisions is improved.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Bone bonding material with high strength and low immunoreaction as well as preparation method and application method of bone bonding material

The invention discloses a high-strength low-immunoreaction bone bonding material and a preparation and application method thereof. The bone binding material comprises tetracalcium phosphate, serine phosphate, magnesium phosphate and a sodium citrate solution. According to the preparation method, tetracalcium phosphate, phosphoserine, magnesium phosphate powder and a sodium citrate solution are fully mixed and reacted by utilizing a hedging device consisting of a screw injector and a connecting pipe. And extruding the mixed liquid material through a filter membrane to complete the preparation of the bone adhesive material. The bone binding material can be used for preparing bionic sclerotin, binding broken bones in comminuted fractures or smearing the bone binding material to bone gaps, and in the decomposition process, the bone binding material can continuously release magnesium ions, so that the immune environment of early bone repair is regulated and controlled, the bone repair process is accelerated, and bone healing is promoted. Meanwhile, experimental data prove that the bone adhesive material provided by the invention can provide stable supporting strength, has no potential toxicity to fibroblasts, and is good in biocompatibility.
Owner:HANGZHOU ORIGO BIOTECHNOLOGY CO LTD

Bone healing time sequence evaluation method, system, equipment and medium

The invention discloses a bone healing time sequence evaluation method, system and device and a medium, and the method comprises the steps: obtaining a multi-time-point CT image data set through an image preprocessing and data enhancement method; performing feature extraction on the CT image at each time point by using a convolutional neural network to obtain spatial features of bone healing; and inputting the extracted features into an LSTM network, capturing time sequence changes between different periods, and finally outputting an evaluation result of the bone healing state through a full connection layer. According to the method, the limitation of single-time-point image analysis in the prior art can be overcome, more accurate and reliable bone healing evaluation is provided, and important decision support is provided for clinicians.
Owner:NANXINDA IMAGING TECH ENG SUZHOU CO LTD

Lumbar interbody fusion cage and implementation method thereof

The invention discloses a lumbar interbody fusion cage and an implementation method thereof.The lumbar interbody fusion cage comprises a base body, the base body comprises an upper end plate and a lower end plate, and the surface curvature of the upper end plate and the surface curvature of the lower end plate are matched with the lumbar interbody curvature of the human body; the porous coatings comprise a single coating and a multi-coating, the porous coatings cover the outer surfaces of the upper end plate and the lower end plate, the porous coatings are made of biological materials, the multi-coating is composed of a plurality of different biological material layers, and each layer of the multi-coating has different porosity and biocompatibility; the supporting structure comprises a flexible hinge, a through hole is formed in the inner side of the base body, the through hole penetrates through the left side and the right side of the base body, and the flexible hinge is matched with the through hole to enable the base body to be bent to a certain extent when the base body is subjected to external force. According to the lumbar interbody fusion cage, through optimization design, the biomechanical suitability, the biocompatibility and the bone healing effect are remarkably improved.
Owner:SUZHOU SINOMED BIOMATERIALS CO LTD

Polyaryletherketone composite implant material as well as preparation method and application thereof

The invention discloses a polyaryletherketone composite implant material and a preparation method and application thereof, and belongs to the technical field of medical materials.The preparation method of the polyaryletherketone composite implant material comprises the following steps that a carbon fiber reinforced polyaryletherketone substrate with the surface provided with a groove structure and conductivity is prepared; based on a precipitation method, a calcium compound, a magnesium compound and a phosphoric acid aqueous solution are used for preparing white calcium stone; the preparation method comprises the following steps: carrying out surface modification on the white calcium phosphate by utilizing polydopamine, so as to obtain modified white calcium phosphate; adding the modified white calcium phosphate and a degradable piezoelectric polymer into a solvent, and mixing to obtain a mixed solution; and coating a carbon fiber reinforced polyaryletherketone substrate with the mixed solution, and performing drying and annealing treatment to form a coating, thereby obtaining the polyaryletherketone composite implant material. According to the invention, the degradable piezoelectric composite coating doped with the white phosphorus calcium stone, which has piezoelectric characteristics and ion release capability, is constructed, so that double biomimetic effects of an electric signal and a chemical signal in a bone healing microenvironment are realized.
Owner:JILIN UNIVERSITY

Design method of structural mechanical gradient regulation and control interbody fusion cage aiming at end plate defect

The invention discloses a design method of a structural mechanical gradient regulation and control interbody fusion cage for end plate defects. The design method comprises the following steps of data acquisition and model construction; analyzing the shape of the defective end plate; carrying out interface mechanical adaptation design on the defect end plate and the structural gradient fusion cage; performing multi-objective optimization; the invention relates to a 3D printing defect endplate mechanical and biological adaptive spinal fusion cage. The individual end plate defect model can be established according to the difference of different patients, the local elastic modulus of the fusion cage is dynamically adjusted through morphological analysis and typing, the stress conduction height matching with the defect end plate is realized, the settlement risk is reduced, and the fusion effect is improved; by combining the biological adaptation design of the end plate, the pore structure and material characteristics of the fusion cage are optimized, and bone healing is promoted; through the scheme of image analysis, digital design, intelligent optimization and precise manufacturing, a mechanical and biological dual-adaptive fusion cage system solution is provided for a patient with the defect of the end plate.
Owner:QIDONG PEOPLES HOSPITAL (QIDONG INST FOR PREVENTION & TREATMENT OF LIVER CANCER)

Resetting and fixing orthopedic equipment for orthopedics department

InactiveCN120616878ARoller massageFractureOrthopedic departmentLocalized swelling
The invention belongs to the technical field of orthopaedic orthopaedics, and particularly discloses a reduction and fixation orthopaedic orthopaedic device for orthopaedics, the upper side and the lower side of a positioning part are slidably connected with sliding rods, the side, close to the sliding rods, of the positioning part is fixedly connected with an adjusting part, and the positioning part comprises two positioning frames. According to the reduction and fixation orthopedic equipment for the orthopedics department, the positioning component is arranged, and a cooling mechanism is arranged in the middle of the inner side of the positioning frame, so that ice compress detumescence can be directly carried out on a bruise position, local swelling and pain caused by fracture or correction operation of a patient are relieved in time, local blood circulation is promoted, and favorable conditions are created for bone healing; when the positioning frame is worn for a long time, the contact mechanism can massage and relieve the corresponding part of the patient, muscle stiffness and discomfort caused by long-time fixation are relieved, the wearing comfort of the patient is improved, and the patient can better cooperate with treatment.
Owner:NO 2 PEOPLES HOSPITAL HUAIAN CITY

A method and a computer program for performing scaffold design optimization towards enhanced bone healing, and a method to manufacture a scaffold

The invention concerns a method, in particular a computer-implemented method, for performing scaffold design optimization (h) towards enhanced bone healing, the method comprising the steps of a) Inputting a set of parameters comprising information about a geometry and a material of a scaffold (3) to a computational model, the computational model comprising a finite element model and a mechano-biological computational model, wherein the finite element model determines and provides a set of mechanical information data for the set of parameters to the mechano-biological computational model, wherein the mechano-biological computational model determines from the set of mechanical information data a regenerated bone volume; b) Determining a plurality of regenerated bone volumes for a plurality of sets of parameters according to step a), such as to generate a scaffold bone data associating the regenerated bone volume with the corresponding set of parameters; c) Determining a computational surrogate model consisting of an analytical expression configured to associate the regenerated bone volumes with the sets of parameters from the scaffold bone data; and d) Determining from the computational surrogate model an optimum set of parameters for which the computational surrogate model puts out a maximum regenerated bone volume. The invention also concerns a computer program and a method to manufacture a scaffold (3).
Owner:DUDA GEORG +1

Knee replacement implants and instruments

Knee arthroplasty implants, instruments, systems, and methods of implanting the same. The knee arthroplasty implants may include a femoral implant and a tibial tray implant, each with trabecular surfaces configured to contact bone to provide a scaffold for bone healing and interdigitation. The implants may also include fixation pegs with bulleted profiles to increase the surface area for bone ingrowth. An inserter instrument may include a sliding rack, which is incrementally extended with a rotatable shaft, thereby allowing for quick lock and release of various tibia trays.
Owner:GLOBUS MEDICAL INC

Titanium-magnesium hollow screw system capable of promoting fracture healing

The invention discloses a titanium-magnesium hollow screw system capable of promoting fracture healing and a manufacturing method. The titanium-magnesium hollow screw system comprises a titanium-based supporting structure and a magnesium filling layer. The titanium-based supporting structure comprises a main body part, the surface of the main body part is provided with an imitated bone trabecula part, and a plurality of bone gaps are formed in the imitated bone trabecula part; wherein bone gaps are filled with the magnesium filling layer, and the magnesium filling layer is combined with the titanium-based supporting structure in a physical embedding mode; the titanium-based supporting structure bears and maintains initial fixation and long-term bearing, so that the strength and the stability of the screw are ensured; the surface imitated bone trabecula and the communicated bone gaps increase the surface area and provide a physical channel for vascularization and bone tissue ingrowth, so that synostosis is promoted; the magnesium filling layer releases magnesium ions after being locally controllably degraded, so that osteogenesis and angiogenesis are favorably stimulated, the local biological environment is improved, instant mechanical support after an operation is ensured, bone healing is promoted through local biological activity release and structural orientation, the healing time is favorably shortened, and the healing quality is favorably improved.
Owner:BEIJING LUHE HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV

Anti-inflammatory osteogenesis-promoting titanium-based implant as well as preparation method and application thereof

The invention discloses an anti-inflammatory osteogenesis-promoting titanium-based implant which comprises a titanium base material, a TiO2 nanotube array layer is constructed on the surface of the titanium substrate in situ; iL-4 is loaded in the TiO2 nanotube array layer, and the surface of the TiO2 nanotube array layer is grafted with a gate molecule mPEG2000-PLGLAL-(PEG4)-C. The invention further discloses a preparation method of the TiO2 nanotube array. The anti-inflammatory osteogenesis-promoting titanium-based implant can respond to MMP concentration change of a surrounding microenvironment so as to regulate and control the release rate of IL-4, in the early stage of bone healing, IL-4 is slowly released, M1 macrophages are dominant, a short and moderate inflammatory reaction is kept, along with response to MMP in the microenvironment, IL-4 is rapidly released, M1 polarization is inhibited, and the osteogenesis-promoting titanium-based implant has the advantages of being good in anti-inflammatory effect and capable of promoting osteogenesis. And inflammation is eliminated in time, M2 polarization is promoted, wound repair is accelerated, osseointegration is further promoted, dynamic regulation of immune response is realized, and a new strategy is provided for promoting bone tissue regeneration through immune regulation.
Owner:SOUTH CHINA UNIV OF TECH

Multifunctional fusion peptide modified 3D printing Ti implant constructed by fusion peptide platform and preparation method and application thereof

The invention belongs to the technical field of biological medicine, and provides a multifunctional fusion peptide modified 3D printing Ti implant constructed by a fusion peptide platform and a preparation method and application thereof. The antibacterial peptide KR-12 and the adhesion peptide GFOGER are simultaneously loaded on the surface of the 3D printing titanium implant through the specific targeting peptide minTBP-1. The sequence of the fusion peptide platform is divided into four main components: bioactive polypeptide sequences KR-12 and GFOGER; a connection unit (Linker); a lysine residue; a specific anchoring group minTBP-1; the composite material has specific loading and slow release capabilities, and utilizes synergistic antibacterial and osteogenesis functions to cope with continuous challenges of implant infection and insufficient osseointegration in biomedical equipment. Meanwhile, sterilization and bone regeneration promotion are achieved, and the method is of great importance to bone healing and enhancement of bone combination around the implant. In addition to the antibacterial effect, the synergistic effect of the antibacterial peptide KR-12 and the adhesive peptide GFOGER can significantly promote osteogenesis of the BMSCs.
Owner:STOMATOLOGICAL HOSPITAL OF SHANXI MEDICAL UNIVERSITY

Shapeable hemostatic putty as well as preparation method and application thereof

The invention provides moldable hemostatic putty as well as a preparation method and application thereof. The hemostatic putty comprises hemostatic powder and a solvent, wherein the hemostatic powder comprises gelatin particles and a polysaccharide compound containing an aldehyde group or a succinimide ester group, and the gelatin particles are cross-linked gelatin particles coated with an active substance. The hemostatic putty disclosed by the invention has good flexibility, moldability, adhesion plugging property and degradability, can be kneaded and molded into any shape to be filled at a bleeding part of a bone wound surface, and forms adhesion plugging on the bleeding part, so that a good plugging hemostatic effect is realized. Active substances are wrapped in a network structure of crosslinked gelatin to form a stable core-shell structure, so that the active substances can be prevented from influencing the adhesion plugging property and hemostatic effect of a final product, and the active substances can be slowly released along with degradation of the gelatin, so that generation of new callus is induced or accelerated, and bone healing is accelerated.
Owner:MEDPRIN REGENERATIVE MEDICAL TECH

Orthopedic surgery risk assessment method and system

The invention relates to the field of orthopedic surgery risk assessment, in particular to an orthopedic surgery risk assessment method and system. The method comprises the following steps: acquiring preoperative data and intra-operative data of an orthopedic surgery of a patient, performing data preprocessing on the preoperative data and the intra-operative data, and extracting bone microstructure spatial features in initial orthopedic surgery data by using a cascade feature extraction network; calculating an association weight of the image data and the biological signal through a cross-modal attention mechanism, and constructing a patient specific skeleton model based on finite element analysis to perform real-time scene simulation on the characteristic orthopedic surgery data; the influence of joint contact stress distribution under different osteotomy angles, a bone implant interface micro-motion threshold after implantation of an internal fixation instrument and hemodynamic changes on a bone healing microenvironment is simulated in real time, complications caused by misoperation are remarkably reduced, and the success rate of an operation is increased.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Hydrogel for remodeling aging microenvironment to promote rotator cuff injury repair and preparation method thereof

PendingCN120132063AProsthesisRotator cuff injuryQuercitrin
The invention discloses hydrogel for remodeling an aging microenvironment and promoting rotator cuff injury repair and a preparation method of the hydrogel. The hydrogel comprises ordered hydroxyapatite super-long nanowire / gelatin-hyaluronic acid composite hydrogel and quercetin loaded in the ordered hydroxyapatite super-long nanowire / gelatin-hyaluronic acid composite hydrogel. According to the ordered hydroxyapatite ultra-long nanowire (AHNW) / gelatin-hyaluronic acid (GH) hydrogel compound loaded with Quercetin, the repairing capacity of bone marrow-derived mesenchymal stem cells (BMSCs) and tendon-derived stem cells (TDSCs) is improved by remodeling an aging microenvironment, so that tendon-bone healing is promoted, the integration effect is improved, and the application prospect is wide. A new treatment strategy is provided for the patient with the rotator cuff injury, especially the patient with the osteoporosis.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL

A method and system for risk assessment in orthopedic surgery

This invention relates to the field of orthopedic surgical risk assessment, and in particular to a method and system for orthopedic surgical risk assessment. By acquiring preoperative and intraoperative data of a patient's orthopedic surgery, the method preprocesses the preoperative and intraoperative data, extracts the spatial features of bone microstructure from the initial orthopedic surgical data using a cascaded feature extraction network, calculates the correlation weights between imaging data and biological signals through a cross-modal attention mechanism, and constructs a patient-specific bone model based on finite element analysis to simulate the characteristic orthopedic surgical data in real time. The method simulates the distribution of joint contact stress at different osteotomy angles, the impact of micromotion thresholds at the bone implant interface and hemodynamic changes on the bone healing microenvironment after internal fixation device implantation, significantly reducing complications caused by improper operation and improving the surgical success rate.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Traumatic injury pill and preparation method thereof

The invention relates to a traumatic injury pill and a preparation method thereof. The twenty traditional Chinese medicinal materials are selected, the production method is optimized according to different characteristics of the traditional Chinese medicinal materials, the Chinese angelica, the divaricate saposhnikovia root and the cassia twig contain volatile components and cannot be treated at a high temperature, temperature-controlled crushing needs to be performed preferentially, and the fried frankincense, the fried myrrh and the catechu are easy to soften in the crushing process, are adhered to a crusher and are not easy to crush, so that the traditional Chinese medicinal materials are difficult to crush. And finally, the powder is mixed and crushed with other medicinal powder, so that the crushing effect can be effectively improved. The obtained traumatic injury pill has the effects of promoting blood circulation to remove blood stasis, relieving swelling and pain and promoting reunion of fractured tendons and bones, and can be used for traumatic injury, tendon fracture and blood stasis swelling and pain.
Owner:HARBIN XIAS ORTHOPEDICS HOSPITAL CO LTD

Application of didymoside in medicine for promoting postoperative tendon-bone interface fibrous cartilage regeneration

The invention discloses an application of didymoside in a medicine for promoting postoperative tendon-bone interface fibrous cartilage regeneration. According to the application, an important way for treating the tendon-bone interface injury and preventing the tendon-bone healing disorder is obtained through the research of macrophages on fibrous cartilage tendon-bone interface repair and the influence of didymoside on interface bone formation and structure, fibrous cartilage formation and macrophage polarization regulation, so that the tendon-bone interface injury is further treated.
Owner:NINGXIA HUI AUTONOMOUS REGION PEOPLES HOSPITAL

Gradient degradation type personalized absorbable sternum fracture fixing plate and preparation process

The invention discloses a gradient degradation type personalized absorbable sternum fracture fixing plate and a preparation process, and belongs to the technical field of medical implant materials. Comprising an anatomical adaptive plate body and an integrated locking assembly, the plate body is of a partitioned structure of a middle supporting area and an edge buffering area, a gradient pore array penetrating through the thickness direction is formed in the surface of the plate body, and a hydroxyapatite-collagen composite coating is loaded on the inner wall of a pore; the plate body is made of a composite absorbable material through 3D printing forming and hot pressing post-treatment, and the composite absorbable material comprises, by weight, 60%-70% of polylactic acid-glycolic acid copolymer (PLGA, LA / GA = 75 / 25), 15%-20% of silanized magnesium alloy microwires, 5%-10% of hydroxyapatite nano-particles and 5%-10% of polycaprolactone (PCL). Space-time matching of the degradation rate and the bone healing process is achieved through the partition gradient structure, the magnesium alloy microwires enhance the mechanical property and release active ions to promote osteogenesis, and the method has the advantages of personalized adaptation, gradient degradation, bone regeneration promotion and the like.
Owner:ZHANGZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE FUJIAN PROVINCE

Swim bladder-based bioactive patch for rotator cuff tendon repair and preparation method of swim bladder-based bioactive patch

The invention provides a swim bladder-based bioactive patch for rotator cuff tendon repair and a preparation method thereof, and relates to the technical field of biological materials.The swim bladder-based bioactive patch is composed of a swim bladder substrate and a metal-phenol toughening network component, has good tensile strength and biological activity and can be used for repairing rotator cuff tendons. The compound can support cell adhesion and proliferation, stimulate differentiation and phenotype maintenance of various cells derived from tendon-bone tissue, and is expected to be used for repairing rotator cuff tendon injury and promoting tendon-bone healing. Besides, the invention provides a preparation method of the swim bladder-based rotator cuff patch, a special microstructure of directionally arranged nano-matrix fibers is reserved, and a metal-phenol network further plays roles in toughening the patch and enhancing the biological activity of the material. Particularly, the metal-network has an active oxygen free radical response function, excessive free radicals at the shoulder joint part can be removed, and metal ions are released, so that the patch has the effects of resisting bacteria, resisting inflammation, resisting oxidation and improving healing.
Owner:AFFILIATED HOSPITAL OF NANTONG UNIV

Fracture fixing device

The invention relates to the field of medical apparatus and instruments, and discloses a fracture fixing device, comprising: a screw comprising a rod body and a screw head connected to one end of the rod body, the rod body being of a hollow structure, the screw head being provided with an opening communicating with the inside of the rod body, the outer side of the rod body being provided with a communicating hole communicating with the inside of the rod body; the degradable part is arranged in the rod body, and the degradable part is right opposite to the communicating hole; a mounting hole is formed in the fixing plate, and the end, away from the screw head, of the rod body penetrates through the mounting hole. After the screw is implanted into a bone, needed mechanical support can be provided, connection and fixation of a fracture part are facilitated, and factors beneficial to bone repair and healing and bacteriostasis and anti-inflammation are released through the degradable part; therefore, bone healing and rehabilitation are better promoted, and the fracture rehabilitation effect is improved.
Owner:HUAMEI MEDICAL TECHNOLOGY (SUZHOU) CO LTD

A medicinal wine for treating sprains and bruises and promoting tendon and bone healing, and its preparation method.

This invention discloses a medicinal wine for treating sprains and bruises, promoting tendon and bone healing, and its preparation method. It belongs to the technical field of bone-healing medicinal wines. This bone-healing wine is made from the following raw materials in parts by weight: 1 part small sprain bone, 1 part large sprain bone, 1 part white crane lingzhi, 1 part moha han, and 10 parts baijiu (Chinese liquor) with an alcohol content of 50 degrees or higher. The preparation method includes: cutting the fresh or dried leaves and branches of small sprain bone, large sprain bone, white crane lingzhi, and moha han into sections, and then soaking the medicinal materials in baijiu with an alcohol content of 50 degrees or higher to obtain this product. This formula can treat sprains and bruises. This invention, as an external medicinal wine for treating sprains and bruises, promotes tendon and bone healing, and has the effects of promoting blood circulation, dispelling wind and dampness, dispersing blood stasis, promoting tendon and bone healing, clearing meridians and collaterals, reducing swelling, promoting blood circulation and removing blood stasis, dispelling wind and relieving pain, tonifying fire and strengthening the body, strengthening tendons and bones, and promoting fracture healing.
Owner:蔡梓豪

A method of depositing hydroxyapatite in a three-dimensional porous sample

PendingCN122272903ABone implantHydroxylapatite
This invention discloses a method for depositing hydroxyapatite in a three-dimensional porous sample, comprising: S1, pretreatment of the three-dimensional porous sample; S2, placing the three-dimensional porous sample in an O... 2 In a plasma spraying apparatus; S3, prepare SBF1, immerse the sample treated in step S2 into SBF1, seal the container tightly, and place it in an incubator. After immersion in SBF1, remove the sample, wash and dry it. SBF1 contains the following components: CaCl2, MgCl2·6H2O, NaHCO3, K2HPO4·3H2O, Na2SO4, KCl, and NaCl; S4, prepare SBF2, immerse the sample treated in step S3 into SBF2, seal the container tightly, and place it in an incubator at 37°C. SBF2 contains the following components: NaCl, CaCl2, and K2HPO4·3H2O; S5, remove the sample, wash and dry it to obtain a three-dimensional porous sample with deposited hydroxyapatite. The method provided by this invention uniformly deposits HA in the porous three-dimensional void surface, and the composite interface can accelerate early bone healing, increase the integration of the bone implant surface with the bone, and promote the early stability of the implant.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

A magnesium alloy composite coating with corrosion resistance for promoting bone healing, its preparation method, and a medical magnesium alloy

The present invention relates to a magnesium alloy composite coating with corrosion resistance for promoting bone healing, a preparation method thereof, and a medical magnesium alloy. The magnesium alloy composite coating includes a bottom coating and a surface coating sequentially arranged from the surface of the magnesium alloy outward. The bottom coating includes microporous channels, and the components of the bottom coating include magnesium hydroxide and / or magnesium oxide. The surface coating includes a polymer material, and the polymer material includes polylactic acid or a mixture of polylactic acid and polycaprolactone. The surface coating fills the microporous channels of the bottom coating and covers the surface of the bottom coating. The magnesium alloy composite coating provided by the present invention is connected in an interlaced and inserted manner by the bottom coating formed by a chemical conversion method and the surface coating formed by a polymer material, has good firmness, strength, and toughness, improves the corrosion resistance of the magnesium alloy, and meets the requirements for promoting bone healing.
Owner:HUA RONG KE CHUANG BIOTECHNOLOGY(TIAN JIN) CO LTD

External electronic patch for accelerating bone healing or regeneration after trauma

An electronic patch, for stimulating tissue healing at a target site, is flexible enough to generally conform to a body surface adjacent to the target site, and includes a battery or an arrangement of multiple batteries less than 5 mm thick; a capacitor connected durectly with a coil in series; and pulse generating circuitry, powered by the battery or batteries. The circuitry repeatedly changes the voltage across the capacitor and coil, to produce pulses of current in the coil. The current produces a pulsed electromagnetic field at the target site for stimulating tissue healing, most of the electromagnetic field energy of each pulse being converted into electrostatic energy of the capacitor at the end of the pulse and back into electromagnetic field energy of the next pulse.
Owner:PULSAR MEDTECH LTD

Portable orthopedic rehabilitation nursing device

The invention discloses a portable orthopedic rehabilitation nursing device, and relates to the technical field of orthopedic rehabilitation nursing. Comprising a thigh bracket, limiting blocks are symmetrically installed at the bottom of the thigh bracket, connecting parts are movably installed on the limiting blocks, limiting holes are formed in the side edges of the connecting parts, the limiting blocks penetrate through the limiting holes, folding rods are arranged at the protruding ends of the connecting parts, and shank brackets are arranged on the folding rods. Arc-shaped holes are formed in the inner side of the shank bracket at equal intervals, a mounting disc is fixedly mounted on the inner sides of the arc-shaped holes, and a jacking assembly is arranged on the inner side of the mounting disc. The jacking assembly is driven through the autonomous leg lifting movement of a patient, joint motion range training and soft tissue massage are combined, the synergistic effect of intermittent axial stress stimulation and the muscle pump effect needed by bone healing is achieved in the non-load-bearing state, and callus formation and venous return are effectively promoted.
Owner:ZHEJIANG UNIV

Orthopedic surgery visualization method, device and equipment and storage medium

The invention relates to the technical field of medical image processing, in particular to an orthopedic surgery visualization method and device, equipment and a storage medium. Through multi-angle shooting of an operation area, providing of rich information, reduction of single-view-angle missing and accurate presentation of an actual situation, elastic imaging data reflects tissue elastic features, in the aspects of feature extraction and model construction, key information of shooting data and a three-dimensional point cloud coordinate set are extracted by using an accelerated robust feature algorithm, and a three-dimensional point cloud coordinate set is obtained. Constructing a rendering elastic model to visually display tissue elastic distribution; meanwhile, relevant data are acquired from a preset database, a skeleton healing evaluation model is constructed by using a clustering analysis algorithm, and the skeleton healing condition is scientifically evaluated; in a data analysis and result application stage, elastic imaging data are analyzed based on the two models to obtain visual data, and doctors are assisted to formulate a reasonable treatment scheme, so that the doctors can comprehensively understand an operation area and make a decision accurately and quickly, and the operation efficiency and quality are improved.
Owner:GUANGZHOU YINGHUIXING TECH CO LTD