104 results about "Bone healing" patented technology

The invention discloses a polyaryletherketone composite implant material and a preparation method and application thereof, and belongs to the technical field of medical materials.The preparation method of the polyaryletherketone composite implant material comprises the following steps that a carbon fiber reinforced polyaryletherketone substrate with the surface provided with a groove structure and conductivity is prepared; based on a precipitation method, a calcium compound, a magnesium compound and a phosphoric acid aqueous solution are used for preparing white calcium stone; the preparation method comprises the following steps: carrying out surface modification on the white calcium phosphate by utilizing polydopamine, so as to obtain modified white calcium phosphate; adding the modified white calcium phosphate and a degradable piezoelectric polymer into a solvent, and mixing to obtain a mixed solution; and coating a carbon fiber reinforced polyaryletherketone substrate with the mixed solution, and performing drying and annealing treatment to form a coating, thereby obtaining the polyaryletherketone composite implant material. According to the invention, the degradable piezoelectric composite coating doped with the white phosphorus calcium stone, which has piezoelectric characteristics and ion release capability, is constructed, so that double biomimetic effects of an electric signal and a chemical signal in a bone healing microenvironment are realized.

The invention discloses a titanium-magnesium hollow screw system capable of promoting fracture healing and a manufacturing method. The titanium-magnesium hollow screw system comprises a titanium-based supporting structure and a magnesium filling layer. The titanium-based supporting structure comprises a main body part, the surface of the main body part is provided with an imitated bone trabecula part, and a plurality of bone gaps are formed in the imitated bone trabecula part; wherein bone gaps are filled with the magnesium filling layer, and the magnesium filling layer is combined with the titanium-based supporting structure in a physical embedding mode; the titanium-based supporting structure bears and maintains initial fixation and long-term bearing, so that the strength and the stability of the screw are ensured; the surface imitated bone trabecula and the communicated bone gaps increase the surface area and provide a physical channel for vascularization and bone tissue ingrowth, so that synostosis is promoted; the magnesium filling layer releases magnesium ions after being locally controllably degraded, so that osteogenesis and angiogenesis are favorably stimulated, the local biological environment is improved, instant mechanical support after an operation is ensured, bone healing is promoted through local biological activity release and structural orientation, the healing time is favorably shortened, and the healing quality is favorably improved.

This invention relates to the field of orthopedic surgical risk assessment, and in particular to a method and system for orthopedic surgical risk assessment. By acquiring preoperative and intraoperative data of a patient's orthopedic surgery, the method preprocesses the preoperative and intraoperative data, extracts the spatial features of bone microstructure from the initial orthopedic surgical data using a cascaded feature extraction network, calculates the correlation weights between imaging data and biological signals through a cross-modal attention mechanism, and constructs a patient-specific bone model based on finite element analysis to simulate the characteristic orthopedic surgical data in real time. The method simulates the distribution of joint contact stress at different osteotomy angles, the impact of micromotion thresholds at the bone implant interface and hemodynamic changes on the bone healing microenvironment after internal fixation device implantation, significantly reducing complications caused by improper operation and improving the surgical success rate.

The invention discloses a gradient degradation type personalized absorbable sternum fracture fixing plate and a preparation process, and belongs to the technical field of medical implant materials. Comprising an anatomical adaptive plate body and an integrated locking assembly, the plate body is of a partitioned structure of a middle supporting area and an edge buffering area, a gradient pore array penetrating through the thickness direction is formed in the surface of the plate body, and a hydroxyapatite-collagen composite coating is loaded on the inner wall of a pore; the plate body is made of a composite absorbable material through 3D printing forming and hot pressing post-treatment, and the composite absorbable material comprises, by weight, 60%-70% of polylactic acid-glycolic acid copolymer (PLGA, LA / GA = 75 / 25), 15%-20% of silanized magnesium alloy microwires, 5%-10% of hydroxyapatite nano-particles and 5%-10% of polycaprolactone (PCL). Space-time matching of the degradation rate and the bone healing process is achieved through the partition gradient structure, the magnesium alloy microwires enhance the mechanical property and release active ions to promote osteogenesis, and the method has the advantages of personalized adaptation, gradient degradation, bone regeneration promotion and the like.

The invention relates to the field of medical apparatus and instruments, and discloses a fracture fixing device, comprising: a screw comprising a rod body and a screw head connected to one end of the rod body, the rod body being of a hollow structure, the screw head being provided with an opening communicating with the inside of the rod body, the outer side of the rod body being provided with a communicating hole communicating with the inside of the rod body; the degradable part is arranged in the rod body, and the degradable part is right opposite to the communicating hole; a mounting hole is formed in the fixing plate, and the end, away from the screw head, of the rod body penetrates through the mounting hole. After the screw is implanted into a bone, needed mechanical support can be provided, connection and fixation of a fracture part are facilitated, and factors beneficial to bone repair and healing and bacteriostasis and anti-inflammation are released through the degradable part; therefore, bone healing and rehabilitation are better promoted, and the fracture rehabilitation effect is improved.

This invention discloses a medicinal wine for treating sprains and bruises, promoting tendon and bone healing, and its preparation method. It belongs to the technical field of bone-healing medicinal wines. This bone-healing wine is made from the following raw materials in parts by weight: 1 part small sprain bone, 1 part large sprain bone, 1 part white crane lingzhi, 1 part moha han, and 10 parts baijiu (Chinese liquor) with an alcohol content of 50 degrees or higher. The preparation method includes: cutting the fresh or dried leaves and branches of small sprain bone, large sprain bone, white crane lingzhi, and moha han into sections, and then soaking the medicinal materials in baijiu with an alcohol content of 50 degrees or higher to obtain this product. This formula can treat sprains and bruises. This invention, as an external medicinal wine for treating sprains and bruises, promotes tendon and bone healing, and has the effects of promoting blood circulation, dispelling wind and dampness, dispersing blood stasis, promoting tendon and bone healing, clearing meridians and collaterals, reducing swelling, promoting blood circulation and removing blood stasis, dispelling wind and relieving pain, tonifying fire and strengthening the body, strengthening tendons and bones, and promoting fracture healing.

This invention discloses a method for depositing hydroxyapatite in a three-dimensional porous sample, comprising: S1, pretreatment of the three-dimensional porous sample; S2, placing the three-dimensional porous sample in an O... 2 In a plasma spraying apparatus; S3, prepare SBF1, immerse the sample treated in step S2 into SBF1, seal the container tightly, and place it in an incubator. After immersion in SBF1, remove the sample, wash and dry it. SBF1 contains the following components: CaCl2, MgCl2·6H2O, NaHCO3, K2HPO4·3H2O, Na2SO4, KCl, and NaCl; S4, prepare SBF2, immerse the sample treated in step S3 into SBF2, seal the container tightly, and place it in an incubator at 37°C. SBF2 contains the following components: NaCl, CaCl2, and K2HPO4·3H2O; S5, remove the sample, wash and dry it to obtain a three-dimensional porous sample with deposited hydroxyapatite. The method provided by this invention uniformly deposits HA in the porous three-dimensional void surface, and the composite interface can accelerate early bone healing, increase the integration of the bone implant surface with the bone, and promote the early stability of the implant.

The invention relates to the technical field of medical image processing, in particular to an orthopedic surgery visualization method and device, equipment and a storage medium. Through multi-angle shooting of an operation area, providing of rich information, reduction of single-view-angle missing and accurate presentation of an actual situation, elastic imaging data reflects tissue elastic features, in the aspects of feature extraction and model construction, key information of shooting data and a three-dimensional point cloud coordinate set are extracted by using an accelerated robust feature algorithm, and a three-dimensional point cloud coordinate set is obtained. Constructing a rendering elastic model to visually display tissue elastic distribution; meanwhile, relevant data are acquired from a preset database, a skeleton healing evaluation model is constructed by using a clustering analysis algorithm, and the skeleton healing condition is scientifically evaluated; in a data analysis and result application stage, elastic imaging data are analyzed based on the two models to obtain visual data, and doctors are assisted to formulate a reasonable treatment scheme, so that the doctors can comprehensively understand an operation area and make a decision accurately and quickly, and the operation efficiency and quality are improved.

The invention belongs to the technical field of biomedical materials, and particularly discloses a zinc-based alloy guided bone regeneration barrier membrane as well as a preparation method and application thereof. Based on Zn, Cu, Li and Mg element selection, by reasonably setting the proportion of each alloy component, the degradable zinc-based guided bone regeneration membrane which has excellent biocompatibility, proper degradation speed, mechanical property, bone healing promotion, bone regeneration capability and antibacterial property is preferably selected; and meanwhile, adverse effects on bone regeneration caused by over-high degradation rate of other metal films such as magnesium alloy and hydrogen generated in the release process of the metal films are also avoided. The Zn-2Cu-0.8 Li-0.2 Mg alloy film is optimally selected from the comprehensive aspects of degradation speed, mechanical property, biocompatibility, guided bone regeneration performance, antibacterial performance and the like, and a high-quality guided bone regeneration material is provided for repairing bone defects such as alveolar bones.

The invention relates to a device for bone formation, bone reshaping or healing of bone in dental, oral and maxillofacial applications, specifically in connection with installation of dental implants. The device comprises a sheet structure made of an inert material, wherein the sheet structure has an inner surface intended to be directed towards the bone and an outer surface intended to be directed away from the bone. The geometrical features of the cavity formed between the inner surface of the device and the initial bone surface when the device is installed at the intended location is further used to improve and plan the treatment. The device is customized by means of digital planning based on the initial and the optimal bone volume for the intended treatment. Modifications of the device can be introduced to facilitate a combined installation of dental implants with the device.

The invention provides a shape memory nano short fiber stent with self-adaptive capacity and preparation and application thereof, and belongs to the technical field of tissue engineering materials. The preparation method comprises the following steps: firstly, preparing flexible polylactic acid-fullerol composite nanofibers containing uniformly dispersed fullerol nanocrystals by utilizing an electrospinning technology, then dividing the flexible polylactic acid-fullerol composite nanofibers into short fibers by virtue of homogenization and freeze-drying processes, and assembling the short fibers into a three-dimensional porous scaffold by taking chitosan as an adhesive. The porous scaffold material disclosed by the invention has excellent biological characteristics and a water-triggered shape memory effect, and due to the fact that chitosan has excellent antioxidant activity and inherent bone induction characteristics, the nanofiber scaffold with the controllable and recoverable shape developed by the invention is expected to effectively promote osteoporotic bone healing.

The invention discloses a bone trabecular bionic implant, and relates to the field of bone trabecular bionic planting, the bone trabecular bionic implant comprises a bone trabecular bionic body, the lower end of the bone trabecular bionic body is fixedly connected with a fixed threaded part, and a reserved filling cavity is formed in the bone trabecular bionic body; an external threaded piece is arranged at the lower end of the bone trabecula bionic body. According to the bone trabecular bionic implant, the whole bone trabecular bionic body is made of a tantalum metal material, the tantalum metal has bone healing force and supporting strength, and the surface of the bone trabecular bionic body is of a porous structure, so that attachment and ingrowth of muscle fulcrums are facilitated, fulcrums are provided for long-term stability of nodules and muscles, exertion of muscle force is facilitated, and the bone trabecular bionic implant has a good application prospect. The bone trabecula bionic body is filled with gel biological factor substances through a reserved filling cavity, the bone trabecula bionic body is mainly applied to implant operation after femoral head necrosis in early and middle stages and drilling decompression, and other drugs can be plugged into micropores in the surface of the bone trabecula bionic body and are slowly released.

Systems, devices and methods are provided for transcutaneously delivering energy impulses to bodily tissues for therapeutic purposes, such as for enhancing the body's bone healing process in spinal fusion patients. A therapeutic stimulator system comprises a housing for an energy source and a signal generator. The system further includes one or more electrodes coupled to the signal generator. A processor is coupled to the housing and configured to determine usage levels of the signal generator and / or motion data of the housing. The system may include a mobile device that allows the patient to input user status data, such as pain levels, and compare the user status data with the usage levels and / or the motion data, thereby improving patient compliance with a prescribed therapy regimen.

The application discloses a kind of polyaryletherketone composite implant materials and preparation method and application, and belongs to medical material technical field, wherein, the preparation method of the polyaryletherketone composite implant material includes the following steps: preparation surface has recess structure and the carbon fiber reinforced polyaryletherketone base of conductivity;Based on precipitation method, white brushite is prepared using calcium compound, magnesium compound and phosphoric acid aqueous solution;White brushite is surface modified using polydopamine, to obtain modified white brushite;Modified white brushite is mixed with degradable piezoelectric polymer into solvent, to obtain mixed solution;Mixed solution is coated on carbon fiber reinforced polyaryletherketone base, after drying, annealing treatment, form coating, to obtain polyaryletherketone composite implant material.The application constructs white brushite doped degradable piezoelectric composite coating with piezoelectric characteristics and ion release capacity simultaneously, realizes the dual bionics of electric signal and chemical signal in bone healing microenvironment.

The invention discloses a computational mechanical analysis system for evaluating bone growth induced by a bone healing scaffold, and relates to the technical field of bone healing evaluation, and the computational mechanical analysis system is specifically characterized in that under unified external load and time gating, quantitative indexes such as a regional average osteogenesis rate curve, an accumulated bone mass, time for reaching a preset healing threshold value, a cross section bridging rate and the like are used for evaluating bone growth induced by a bone healing scaffold; the induction osteogenesis effects of different stent structures are fairly compared, shape scoring and subjective weight are avoided, reproducibility and calibration are emphasized, the method can be used for preoperative structure screening and parameter sensitivity analysis and can also be in butt joint with follow-up images and experimental data, online calibration and treatment course optimization of individualized digital twinning are further supported, and the method is suitable for popularization and application. According to the method, the period boundary, the time-varying supply gating and the multi-physics field coupling of the RVE can be unified into the same calculation framework, and the defects of the prior art in microscopic geometric maintenance, time rhythm expression and biomechanical closed loop are effectively overcome.

The invention discloses traditional Chinese medicine external medicinal liquor for treating bone diseases and a preparation method and application thereof. The medicinal liquor is prepared from, by weight, 30 g of ginseng under forest, 60 g of raw radix astragali, 90 g of dragon's blood, 60 g of sargentgloryvine stem, 30 g of radix clematidis, 60 g of radix angelicae, 30 g of scorpion, 60 g of lumbricus, 60 g of dried river crab, 30 g of silkworm larva, 60 g of ground beetle, 30 g of frankincense, 30 g of myrrh, 60 g of teasel root and 60 g of rhizoma drynariae. The traditional Chinese medicine is prepared from 60 g of native copper, 30 g of amber, 30 g of pericarpium zanthoxyli, 25 g of radix aconiti, 25 g of radix aconiti agrestis, 60 g of caulis spatholobi, 30 g of cortex erythrinae, 45 g of semen strychni, 15 g of musk and 30 g of borneol. The medicinal liquor achieves the effects of rapidly relieving swelling and pain, promoting bone healing, dispelling wind and eliminating dampness and the like through the synergistic effect of multiple targets, is especially suitable for arthralgia type osteoarticular diseases and traumatic injuries, and has remarkable curative effects on osteoproliferation, fracture recovery and the like and high safety according to clinical cases.

The invention provides a novel biodegradable magnesium-hydroxyapatite-graphene biological material system for an advanced orthopedic implant, and relates to the technical field of implants, and the novel biodegradable magnesium-hydroxyapatite-graphene biological material system for the advanced orthopedic implant comprises magnesium, hydroxyapatite and a graphene nanosheet. Hydroxyapatite and graphene nanosheets are uniformly distributed in a magnesium matrix, and the mechanical property is very close to that of a human skeleton; the mechanical adaptation of magnesium is combined with the osseointegration performance of hydroxyapatite and the strengthening and corrosion resistance of the graphene nanosheets, the orthopedic implant is naturally integrated in vivo and can be gradually decomposed and completely degraded in vivo, the problem that traditional non-degradable materials (such as titanium or stainless steel) need to be taken out through a secondary operation is solved, the graphene nanosheets inhibit pitting corrosion, and the mechanical property of the orthopedic implant is improved. The corrosion rate is reduced by about 50%, the orthopedic implant has corrosion resistance, the service life of the implant is prolonged, and hydroxyapatite promotes bone growth and accelerates bone healing.

The invention discloses an ultrasonic bone healing therapeutic apparatus which comprises a probe and a host which are in signal connection. The host comprises a shell, a control assembly, a battery, a display assembly and a key assembly, the control assembly comprises a microcomputer main control module, a signal excitation module, a power amplifier module and a terminal matching module, and the microcomputer main control module is in signal connection with the display assembly, the key assembly, the signal excitation module, the power amplifier module and the no-load protection module; the terminal matching module is in signal connection with the power amplifier module, the no-load protection module and the probe. And the microcomputer main control module adopts a PWM (Pulse Width Modulation) technology to control the frequency and the pulse width of a modulation signal by outputting a pulse square wave to obtain modulation sine wave signals with different duty ratios. The device is small in size, convenient to carry and suitable for families, hospitals, outdoors and other scenes; the battery is a rechargeable lithium battery and can be suitable for an outdoor scene without a power supply; moreover, the charger can be used for many times through one-time charging.

The invention discloses a magnesium-based bone implant material surface modified composite coating and a preparation method thereof, and relates to the technical field of biomedical materials. The modified composite coating comprises a micro-arc oxidation ceramic layer, a bone healing promoting functional layer and an antibacterial functional layer, wherein the micro-arc oxidation ceramic layer covers the surface of the magnesium-based bone implant material; the bone healing promoting functional layer and the antibacterial functional layer are sequentially loaded on the micro-arc oxidation ceramic layer; the bone healing promoting functional layer comprises a sustained-release material and icariin wrapped in the sustained-release material; the antibacterial functional layer comprises antibacterial peptide, and the antibacterial peptide is grafted on the bone healing promoting functional layer. The composite coating effectively regulates and controls release behaviors of bone healing promoting components and antibacterial components, and realizes dynamic regulation of a microenvironment of a bone repair part; moreover, the magnesium-based bone implant material also has excellent biocompatibility, can provide a good cell basis for bone regeneration, and is beneficial to large-scale application of the magnesium-based bone implant material in bone wound healing.

The utility model relates to a kind of nanostructure of laser surface treatment aggregate, wherein the surface of the aggregate is titanium metal, and at least one microchannel with titanium dioxide (TiO2) after cooling is formed by laser melting and sputtering to form molten titanium, at least one microchannel includes: at least one micropore, at least one guide channel, and at least one nano-wall formed at least one nano-bulge layer and at least one nano-wall. The following bone healing and antibacterial index effects and purposes are achieved: A. accelerate bone healing related protein deposition, B. accelerate bone cell attachment, C. induce neovascularization, D. accelerate early calcification and bone mineralization, E. improve nutrient exchange, F. stabilize surface bone structure, and G. resist plaque formation.

The present invention relates to a customized device made of inert and rigid ceramics for rebuilding bone, bridge bone defects or reshaping bone, and more particularly, to the combination of material properties and design to protect fractured portions or volumes to form new bone from movements and external forces that may interfere with bone formation and bone healing. This contributes to the best situation for natural bone healing, thereby improving clinical outcomes. The design of the implant member (1) is based on the initial bone structure (2) and the intended treatment, in which at least a portion of the bone-oriented inner surface (9) of the implant member (1) follows irregularities of the initial bone structure (2) to mechanically support the area around the fixation screws (6) for connecting the implant member to the initial bone structure (2).

The utility model provides an acetabulum posterior wall fixing plate, and belongs to the technical field of medical instruments. The acetabulum posterior wall fixing plate comprises a fixing transverse plate and a fixing hook plate, a plurality of sets of first fixing holes are formed in the fixing transverse plate, the fixing hook plate is arranged on the upper end face of the fixing transverse plate, and the hook portion of the fixing hook plate is arranged towards the inner side wall, close to the bone surface, of the fixing transverse plate. The acetabulum posterior wall fixing plate is suitable for treating acetabulum posterior wall fractures, acetabulum posterior column fractures and acetabulum edge posterior wall fractures, the fixing hook plate is arranged at the upper end of the fixing transverse plate, the fixing hook plate is hung on the acetabulum posterior wall of a patient, fixing of a device is facilitated, stable fixing of the acetabulum edge fractures is facilitated, and the acetabulum posterior wall fixing plate is suitable for being used for treating acetabulum posterior wall fractures, acetabulum posterior column fractures and acetabulum edge posterior wall fractures. The fixing plate can be used independently, and can also be matched with other fixing plates for cooperative fixation.

A biodegradable, biocompatible metal alloy composition suitable for orthopedic implants, consisting of magnesium as the main component (at least 50 wt%) and at least one alloying element selected from calcium, zinc, manganese and strontium, wherein the alloy exhibits a controlled degradation rate and sufficient mechanical strength under physiological conditions to support bone healing.

The invention provides a preparation method and application of a fiber material with a nanopore structure. The preparation method of the fiber material with the nano-pore structure comprises the following steps: preparing polyether-ether-ketone fibers, constructing a chelate coating formed by chelating phytic acid and strontium ions on the surfaces of the polyether-ether-ketone fibers, and carrying out electron bombardment treatment on the chelate coating to form the nano-pore structure on the surfaces of the chelate coating. The application is that the fiber material with the nano-pore structure is woven into the artificial ligament fabric. According to the invention, the biological activity of strontium, the chelation function of phytic acid and the physical advantages of a nano-pore structure are creatively combined to realize a synergistic effect of multiple functions, continuous and controllable strontium ion release can be provided, osteogenesis biochemical signals can be activated, bionic physical attachment points are provided for cells, cell behaviors are guided, and the bioactivity of the cells is improved. The composite material can be used for adjusting the microenvironment around the implant and relieving oxidative stress injury, provides a novel solution and material for promoting tendon-bone healing and bone regeneration, and has great popularization and application values.

The application discloses a bone implant with a lampshade-expanding locking and self-energy-supplying coating and a preparation method thereof, and belongs to the medical implant field. The bone implant is designed according to the contraction structure of a lampshade, is in an elongated form below a martensite phase transition temperature, and is in an open lampshade form above an austenite phase transition temperature. The bone implant realizes self-adaptive expansion and surface locking in a marrow cavity by using the super-elasticity and shape memory effect of a memory alloy, and provides instant three-dimensional mechanical stability beyond traditional bone plates and intramedullary nails. The surface of the bone implant is coated with a functional gradient coating, which can actively capture biochemical energy and mechanical energy in the body, and intelligently and time-sequentially regulate growth factor release and cell behavior according to the biochemical energy and the mechanical energy, so that the continuous glucose metabolism and physiological activities in the body are directly converted into electric energy and control signals for driving bone healing, and energy self-provision and logic autonomy are realized.

The invention relates to the field of medical instruments, and discloses an assembly for promoting bone healing, comprising: an implantation main body, the surface of which is provided with a mounting hole; the degradable part is arranged in the mounting hole, an open groove is formed in the surface of the degradable part, and the degradable part is elastically extruded in the direction from the outer side to the open groove, the degradable part is stably arranged in the implantation body, healing factors can be released in an oriented mode according to the operation position, the bone healing rehabilitation speed is increased, and the operation efficiency is improved. In addition, the implantation main body keeps providing a required mechanical supporting function for an operation position, so that the bone healing and rehabilitation effect can be ensured.

The application provides biodegradable bone glue and a preparation method and use thereof, and belongs to the technical field of biological medicine. The bone glue is prepared from raw materials in a mass ratio of europium-doped polyphosphoric calcium: phosphorylated amino acid: polyacrylic acid: polyether glycol: metal-carboxyl-containing aromatic compound coordination complex=(1-3):(1-3):(2-5):(2-4):(0.1-0.3). The bone glue has significantly improved adhesion in a humid biological environment, and has excellent injectability, adhesion and low interfacial adhesion, and also has excellent biocompatibility, antibacterial and anti-inflammatory activity and osteogenesis promoting activity, effectively improves inflammation and oxidative stress problems in the bone healing process, and provides a more efficient and reliable repair material for clinical bone repair.

The application provides a graphene oxide hydrogel for treating rotator cuff injury and a preparation method thereof, and relates to the technical field of medical materials. The preparation method comprises the following steps: uniformly dispersing graphene oxide into water to form a graphene oxide suspension; dissolving a water-soluble synthetic high-molecular skeleton material in water to obtain a skeleton material solution, and then adding a pore-forming auxiliary agent to form a mixed solution after dissolution; and sequentially adding the graphene oxide suspension, an anion crosslinking agent and a solution stabilizer into the mixed solution, and then uniformly mixing, cooling to room temperature, low-temperature freezing and freeze-drying to obtain the graphene oxide hydrogel. In-vivo evidence is provided, which proves for the first time that the above material can promote microfracture treatment of rotator cuff injury and significantly enhances tendon-bone healing in a rat model. A transformable combination strategy is verified, which directly solves the limitation of microfracture lacking of a support, and provides a promising method for improving rotator cuff repair.

This invention discloses a traditional Chinese medicine composition for bone setting and burn treatment based on a family secret recipe, and its application. The composition is a powder preparation, processed using a specific technique. For internal use in bone setting and tendon repair, it should be taken with warm yellow rice wine. After taking the medicine, the patient should sweat profusely, with dampness in the wrists and ankles, and strictly avoid foods such as eggs, beef, mutton, donkey, horse, dog meat, old sow, and boar meat until the fracture has clinically healed. For external use in treating burns, the powder should be mixed with sesame oil to form a paste and applied to the wound. No pre-sterilization is required. Blisters should be punctured before applying the medicine. This composition significantly promotes bone healing (cycle 2-8 weeks) and burn wound healing (cycle 1-8 weeks), leaving no scars after burn healing, with a cure rate of over 99.7% and no toxic side effects.

The present invention provides a nanostructure of a laser surface-treated bone material. [Solution] The surface of the bone material is titanium metal 3, and molten titanium metal is formed by laser sputtering. After cooling, it has at least one microchannel 10 made of titanium dioxide (TiO2). The nanostructure of the bone material includes at least one micropore 12, at least one guide channel 16, at least one nanoprotrusion particle layer 111 formed by at least one nanowall 11, and at least one nanowall. The effects and purposes of improving bone healing and antibacterial indicators are achieved: A. accelerating the deposition of bone healing-related proteins; B. accelerating the attachment of bone cells; C. inducing neovascularization; D. accelerating early calcification and bone mineralization; E. improving the exchange of nutrients; F. stabilizing the surface bone structure; and G. inhibiting plaque formation.