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41 results about "Diabetic gastroparesis" patented technology

Diabetic gastroparesis is a type of nerve damage that slows digestion. High blood sugar levels from diabetes can damage nerves and tissues in your stomach. The damage prevents your stomach from emptying normally.

Therapy for enteric infections

ActiveUS8772242B2Antibacterial agentsBiocideNervous systemDiverticulitis
There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhea, chronic idiopathic nausea, IBD-associated constipation and diarrhea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment.
Owner:BORODY THOMAS JULIUS

A kind of pharmaceutical composition for treating diabetes

The invention discloses a medicinal composition for treating diabetes. The medicinal composition consists of astragalus, gardenia, Szechuan lovage rhizome, siberian solomonseal rhizome, finger citron, root of red-rooted salvia, cinnamomvine, swordlike atractylodes rhizome, white paeony root, perilla fruit, kudzuvine root, fragrant solomonseal rhizome, oyster shell, rehmannia root, Chinese angelica, common anemarrhena rhizome, honeysuckle flower, heartleaf houttuynia herb, fresh imperata root, Chinese caterpillar fungus, semen nelumbinis, siberian solomonseal rhizome, cornus fruit, prepared rehmannia root, villous amomum fruit, liquoric root, medlar, asparagus, black sesame, tuckahoe, cherokee rose fruit, cistanche deserticola, angelica dahurica, adenophora, dark plum fruit, complanate astragalus seed, cassia seed, mulberry leaf, fresh reed rhizome, mint, oriental waterplantain rhizome, wrinkled gianthyssop herb and parslane herb. The medicinal composition can control the blood sugar level of various patients who suffer from the diabetes and improve the clinical symptoms of diabetes complications effectively. Therefore the medicinal composition can be used for treating the diabetesand the diabetes complications such as diabetic gastroparesis, diabetic nephroma, diabetic foot, diabetic neuropathy, diabetic eye diseases and diabetic pruritus and the like.
Owner:赵国辉

Traditional Chinese medicine preparation for assisting acupuncture treatment of diabetic gastroparesis and preparation method and applications thereof

The invention discloses a traditional Chinese medicine preparation for assisting acupuncture treatment of diabetic gastroparesis and a preparation method and applications thereof. The traditional Chinese medicine preparation is prepared from the following raw materials in parts by weight: 8-10 parts of astragalus membranaceus, 8-10 parts of codonopsis pilosula, 8-10 parts of atractylodes macrocephala koidz, 3-6 parts of fructus amomi, 6-8 parts of hovenia dulcis, 6-8 parts of salvia miltiorrhiza and 6-8 parts of endothelium corneum gigeriae galli. The traditional Chinese medicine preparation is prepared by decocting raw herbal materials with water, then extracting and concentrating. Pharmacodynamic experiments show that the traditional Chinese medicine preparation for assisting acupuncture treatment of diabetic gastroparesis has no obvious adverse reaction, and is safe and reliable; the preparation can be used for promoting the increase of body mass, food intake and stool quantity of mice with diabetic gastroparesis, relieving the gastric electrical activity confusion and improving the gastric antrum ICC ultrastructure very well, so that the expression of positive ICC and SP positive materials of gastric antrum c-kit can be enhanced, and the positive expression of nNOS can be lowered; and the preparation has a good improvement effect on the number increasing, form and signal transduction function of ICC.
Owner:陕西罗麻丹医药有限公司

A traditional Chinese medicine for treating chronic atrophic gastritis and a preparation method thereof

The purpose of the present invention is to provide a traditional Chinese medicine for treating chronic atrophic gastritis and a preparation method thereof, wherein the traditional Chinese medicine includes cassia twig, red ginseng, poria, amomum fruit, alpinia fruit, baked ginger, ginger, cardamom, and prepared pinellia. The traditional Chinese medicine of the present invention has good reversal, alleviating or eliminating effect to intestinal metaplasia pathological changes of chronic atrophic gastritis, and currently, no obvious adverse reactions and side effects are found, so the medicine is safe and reliable. The traditional Chinese medicine of the present invention has good gastric motility promoting effect, and can also be applied to the treatment of patients having functional gastrointestinal disorders with poor gastrointestinal motility, such as the gastroesophageal reflux disease, bile reflux gastritis, functional dyspepsia, diabetic gastroparesis and functional constipation.
Owner:LIUZHOU HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine for treating diabetic gastroparesis

The invention discloses a traditional Chinese medicine for treating diabetic gastroparesis, belonging to the technical field of pure traditional Chinese medicine. The traditional Chinese medicine for treating diabetic gastroparesis comprises pseudostellaria root, Radix Astragali, Chinese yam, bighead atractylodes rhizome, cuttlefish bone, calcined clam shell, hedgehog skin, mutmeg, Hindu daturae flower, immature orange fruit, perilla stem, banksia rose, medicinal evodia fruit, bitter orange, officinal magnolia bark, finger citron, toosendan fruit, silktree albizia bark, vine of tuber fleeceflower, Chinese thorowax root, nutgrass galingale rhizome, radish seed, ginger, pinellia tuber, rehmannia root and hemp seed. A dose of the traditional Chinese medicine is taken each day and decocted twice; 350 to 450 ml of the obtained decoction is extracted and divided into two parts which are respectively taken after meal. Through combination of the above-mentioned bulk drugs, the traditional Chinese medicine exerts spleen-invigorating, qi-benefiting, blood circulation-promoting, blood stasis-dispelling, qi-rectifying, pain-relieving, stomach-harmonizing and adverse-rising energy-claming effects. The traditional Chinese medicine is better than the western medicine--cisapride, has the advantages of small side effects, flexibility in usage, suitability for long-term treatment and a treatment effective rate of more than 93% and is worth popularization and application.
Owner:南阳市宛城区第一人民医院 +1

Treatment for gastroparesis using sepiapterin

The present invention discloses that diabetic rats showed a reduction in nitrergic relaxation of the gastric, impaired nNOS dimerization, decreased BH4 and GTPCH1 levels and thus, are more susceptible to develop diabetic gastroparesis. The use of tetrahydrobiopterin and its derivatives and sex steroid hormones as disclosed herein provides a novel strategy for therapeutic intervention of diabetic gastroparesis and any other gut-related diseases. Additionally, the present invention also discloses methods to determine risk of developing gastroparesis in an individual that are drawn to detecting variations in the activity and levels of GCH gene and in gene encoding sex steroid hormone receptor.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Therapy for enteric infections

ActiveUS20120202738A1Antibacterial agentsBiocideNervous systemDiverticulitis
There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhoea, chronic idiopathic nausea, IBD-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the composition comprising: (i) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers diarrhoea, chronic idiopathic nausea, IBD-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinsons disease, MS, Alzheimers Disease, Motor Neurone Disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment.
Owner:BORODY THOMAS JULIUS

Novel enteric combination therapy

There is disclosed herein a composition for treating gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers' diarrhoea, chronic idiopathic nausea, IBD-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinson's disease, MS, Alzheimer's Disease, Motor Neurone Disease or autism, the composition comprising: (i) at least two anti-Clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (ii) at least one anti-Clostridial agent selected from the above combined with an opioid blocking agent. There is also disclosed herein a method of treating various gastrointestinal or neurological disorders, constipation, functional constipation, irritable bowel syndrome, diverticulitis, travelers' diarrhoea, chronic idiopathic nausea, IBD-associated constipation and diarrhoea, pseudo-obstruction, diabetic gastroparesis, cyclic vomiting, reflux oesophagitis, autism enteropathy, flatulence, halitosis, chronic fatigue, bloating, proctalgia fugax, Parkinson's disease, MS, Alzheimer's Disease, Motor Neurone Disease or autism, the method comprising administering orally, via enema or by suppository: (i) a composition of the invention; (ii) at least two anti-Clostridial agents selected from the group consisting of: vancomycin, vancomycin derivatives, a multi-valent polymer of vancomycin, aminoglycosides, nitroimidazoles, ansamysins, nifuroxazide, colchicine, prucalopride, prokinetic agent and 5-aminosalicylic acid; or (iii) at least one anti-Clostridial agent selected from the above and an opioid blocking agent to a patient in need of such treatment.
Owner:BORODY THOMAS JULIUS

Pressure measuring device for stomach pressure measuring method examination of diabetic gastroparesis patient

The invention discloses a pressure measuring device for stomach pressure method examination of a diabetic gastroparesis patient, which comprises a main body bin serving as a main frame of the pressure measuring device for stomach pressure method examination, a positioning rotating shaft connected to the upper side of the rear surface of the main body bin, and a sealing plate connected to the outer side of the positioning rotating shaft, meanwhile, a positioning buckle is fixed to the front surface of the sealing plate, the detection pipe is arranged on the outer side of the detection end in a sleeving and sealing mode, the tail end of the detection pipe is connected with a pressure detection module, and the pressure detection module is electrically connected with the display control panel; and the signal conversion module is arranged at the central position of the front surface of the detection bin. The pressure measuring device for stomach pressure method examination of the diabetic gastroparesis patient is simple in overall structure and convenient to disassemble and assemble, the gastrointestinal contraction function of the patient can be detected, information can be intelligently stored and recorded, and follow-up comparison of medical staff can be facilitated.
Owner:南通市第一老年病医院

Constraint type stomach massager for diabetic gastroparesis patient

The invention discloses a constraint type stomach massager for the diabetic gastroparesis patient, which comprises a body and a massage frame; a constraint belt is connected to the lower side of the body, a positioning clamping groove is formed in the outer side of the body, a positioning protruding block is fixed to the inner side of the positioning clamping groove, and a splicing assembling block is connected to the outer side of the positioning protruding block; positioning sliding grooves are formed in the inner sides of the splicing assembling blocks, buffer bins are fixed to the inner sides of the splicing assembling blocks, positioning springs are arranged in the buffer bins, adjusting plates are arranged on the inner sides of the positioning springs, the massage frame is arranged on the inner sides of the positioning sliding grooves, and massage bins are arranged on the inner side of the massage frame. According to the invention, multiple groups of splicing assembly blocks canbe communicated through the arranged positioning sliding grooves, so that the subsequent massage frame can slide conveniently, the normal use of the device is facilitated, the friction force between the splicing assembly blocks and the massage frame can be reduced through the arranged balls, and the service life of the massage frame can be prolonged.
Owner:THE SECOND PEOPLES HOSPITAL OF NANTONG

Pressure measuring device for stomach pressure measuring method examination of diabetic gastroparesis patient

PendingCN114569106AAvoid damageAvoid problems with rubbing the patient's nasal passagesCatheterLavatory sanitoryNasal passagesNasal Cavity Epithelium
The invention discloses a pressure measurer for stomach pressure method examination of diabetic gastroparesis patients, which comprises a recorder, a display screen is embedded in the front surface of the recorder, a control box is mounted below the recorder, and the right side of the control box is slidably connected with a telescopic plate; the telescopic adjuster is fixed to the upper surface of the right end of the telescopic plate, a shaping hose is installed on the right side of the telescopic adjuster, a threaded connector is in threaded connection with the outer side of the lower end of the shaping hose, a detection sleeve is integrally connected to the lower end of the threaded connector, and a positioning balloon is installed on the outer side of the lower end of the detection sleeve. A detection inner pipe is installed in the lower end of the detection sleeve in a telescopic mode, and a detection window is formed in the outer side of the lower end of the detection inner pipe. The pressure measuring catheter is provided with the detection sleeve and the detection inner tube, the detection inner tube can be telescopically adjusted relative to the detection sleeve, the problem that the nasal cavity of a patient is rubbed due to the fact that the pressure measuring catheter is integrally telescoped is effectively solved, and damage to the interiors of the noses of the patient can be reduced.
Owner:彭婷瑜

Composition for treating diabetic gastroparesis and application thereof

The invention belongs to the field of traditional Chinese medicine application, and particularly discloses a composition for treating diabetic gastroparesis and an application thereof. The composition contains ginseng, bighead atractylodes rhizome, colla corii asini, polygonum multiflorum, fructus lycii, semen cassiae, aloe and fructus aurantii immaturus. The traditional Chinese medicine adopts pure traditional Chinese medicine raw materials, is complete in monarch, minister, assistant and guide, and is suitable for cases. The clinical medication feedback shows that the composition can effectively treat gastroparesis syndrome, especially diabetic gastroparesis, and is short in treatment course and good in effect; and animal experiments show that the effective rate of the medicine for treatment is 95% or above. The traditional Chinese medicine composition can be added into health-care products and food according to a certain proportion to prepare products with the same curative effect.
Owner:LUNAN PHARMA GROUP CORPORATION
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