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A traditional Chinese medicine composition for treating diabetic gastroparesis and its preparation method

A technology of diabetic gastroparesis and composition, which is applied to the traditional Chinese medicine composition and its preparation for treating diabetic gastroparesis, and the field of traditional Chinese medicine composition and its preparation, which can solve problems such as fatigue, short duration of effect, unsuitable for long-term use, etc.

Active Publication Date: 2020-09-11
DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, although western medicine for the treatment of gastroparesis has quick results, the duration of the effect is short, and there are many adverse reactions such as fatigue, drowsiness, lactation, etc., and it is not suitable for long-term use.

Method used

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  • A traditional Chinese medicine composition for treating diabetic gastroparesis and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Raw materials: bergamot 10g, citron 10g, Cyperus cyperi 10g, inula 10g, ocher 10g, black medicine 10g, tangerine peel 10g, heterophylla 30g, pinellia 10g;

[0033] Preparation method: Take the above-mentioned raw materials in proportion, add water to decoct twice, each time for 1 hour, filter, and combine the decoctions to obtain the product.

Embodiment 2

[0035] Raw materials: bergamot 9g, citron 13g, Cyperus cyperi 9g, inula 13g, ocher 9g, black medicine 12g, tangerine peel 8g, heterophylla 32g, pinellia 9g;

[0036] Preparation method: Take the raw material drug in proportion, add 60% ethanol to reflux extraction twice, each time for 1 hour, filter, and combine the filtrates to obtain the product.

Embodiment 3

[0038] Raw materials: bergamot 14g, citron 8g, Cyperus cyperi 15g, inula 9g, ocher 13g, black medicine 9g, tangerine peel 13g, heterophylla 28g, pinellia 15g;

[0039] Preparation:

[0040] In step a, the volatile oils of bergamot, citron, and cyperus are extracted by steam distillation to obtain volatile oils, aqueous solutions, and medicinal residues; the medicinal residues are extracted with water, and the extract and aqueous solution are combined to obtain extract A;

[0041] Step b, adding water to extract ocher, tangerine peel, inula, heterophylla, pinellia, and black medicine six flavors to obtain extract B;

[0042] Step c, combine the extracts A and B, precipitate with alcohol, the ethanol solubility is 60%, filter, recover ethanol from the filtrate, and concentrate.

[0043] In step d, the concentrated solution obtained in step c is mixed with the volatile oil obtained in step a to obtain the product.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating diabetic gastroparesis. The traditional Chinese medicine composition is prepared from active pharmaceutical ingredientsincluding fructus citri sarcodactylis, fructus citri, rhizoma cyperi, inula flowers, ochre, radix linderae, pericarpium citri reticulatae, radix pseudostellariae and rhizoma pinelliae. The traditional Chinese medicine composition can be used for obviously relieving relevant symptoms of diabetic gastroparesis patients. The total effectiveness rate reaches 93.3 percent.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating diabetic gastroparesis and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Diabetic gastroparesis (DGP), also known as diabetic gastroparesis or diabetic gastric retention, is one of the common chronic complications of diabetes; it is a clinical syndrome characterized by decreased gastric motility, slow gastric emptying, and gastric rhythm disorder ; Common symptoms include nausea, vomiting, abdominal distension, early satiety, loss of appetite, and there may be only disturbance of gastric motility without obvious symptoms. In recent years, DGP has been on the rise with the increase of the incidence of diabetes. It has been reported that among diabetic patients, the incidence of gastrointestinal motility disorder...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61K47/69A61P3/10A61P1/00A61P11/14A61K33/26
CPCA61K33/26A61K36/28A61K36/36A61K36/54A61K36/752A61K36/8888A61K36/8905A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 杨晓晖
Owner DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE
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