523 results about "Hydrophobic polymer" patented technology

The invention belongs to the technical field of hydrophilic gel and water extraction from air, and particularly relates to surface-hydrophobic core-shell structure composite moisture absorption hydrogel and a preparation method and application thereof.The preparation method specifically comprises the steps that hydrophilic gel loaded with moisture absorption salt is placed in a hydrophobic polymer solution, and a phase inversion method is used for preparing the core-shell structure composite moisture absorption hydrogel; a porous hydrophobic polymer shell layer is loaded on the surface of the hydrophilic gel, so that the composite moisture absorption hydrogel with the moisture absorption salt loaded hydrophilic gel as a core layer and the porous hydrophobic polymer as the shell layer is obtained, and the prepared composite moisture absorption hydrogel can prevent leakage of the moisture absorption salt and is high in water absorption performance, good in long-term use stability and simple in preparation method. The prepared composite moisture absorption hydrogel can be widely applied to the fields of air water taking, humidity control and agricultural moisturizing.

The invention discloses a hydrophobic-hydrophilic Janus water collecting film and an efficient preparation method thereof, and belongs to the field of water collecting materials. An electrostatic spinning process is adopted, and a hydrophobic polymer is accurately deposited on the surface of a hydrophilic substrate in the form of a nanofiber array, so that the Janus composite membrane with an asymmetric wetting gradient structure is successfully constructed. The unique double-sided wettability difference drives the liquid drops to realize directional transmission, and the core mechanism of the liquid drops is derived from capillary force regulation and control caused by interfacial wetting potential energy difference. The Janus membrane shows excellent performance in the aspect of air moisture trapping, the ultra-fast moisture absorption characteristic and the surface regeneration capacity are achieved, and compared with a traditional single-layer hydrophilic membrane, the water collecting efficiency is remarkably improved by 110%. A one-step forming process is adopted for preparation, the diameter of the nanofibers is controllable, complex post-treatment procedures are not needed, and energy consumption required by equipment is low. The high-performance water collecting film has important application value in the fields of atmospheric water taking in arid regions, dehumidification of precise instruments and the like.

The invention provides a fiber dressing for promoting wound healing and a preparation method and application thereof, and belongs to the technical field of biological materials. The shell of the fiber dressing contains the first medicine for promoting polarization of macrophages, and the first medicine can promote polarization of macrophages at normal and diabetic wound surfaces from M1 type to M2 type; a shell substrate is a mixture of hydrophilic and hydrophobic polymers, so that painless adhesion and stripping of a wound surface can be realized by absorbing seepage and spraying non-irritant normal saline on the wound surface, and secondary injury of the wound surface is reduced; an inner core contains a second medicine and a third medicine which are used for inducing death of M1 type macrophages, so that wound inflammatory response can be reduced, wound bacteria can be killed, wound infection degree can be reduced, and wound healing can be accelerated; the core matrix is a mixture of hydrophilic and hydrophobic polymers with good biocompatibility, can provide mechanical support for the fiber dressing, and provides a slow release effect for the two substances in the core. By controlling the composition of the inner core and the shell, the healing of normal wounds and diabetic wounds can be effectively promoted.

The invention discloses a conductive and heat-conducting hydrophobic polymer composite membrane as well as a preparation method and application thereof. The method comprises the following steps: preparing a PU nanofiber membrane through an electrostatic spinning technology; then AgNPs is adsorbed on the surface of the PU nanofiber through an interface hydrogen bond, contact thermal resistance and resistance are effectively reduced, MWCNTs are attached to the upper surface and the lower surface of the composite film through suction filtration and hot pressing, a sandwich structure is formed, and hydrophobicity is guaranteed while the resistance and the thermal resistance are further reduced. The resistance and the heat conductivity of the polymer composite film respectively reach 14.8 m omega / sq and 7.9 W (m K) <-1 >, and the water contact angle is 132.8 degrees. The excellent durability of the composite film is guaranteed through strong interface interaction, and the composite film has potential application prospects in multifunctional electric conduction and heat conduction composite materials.

The invention discloses a preparation method of a lithium metal negative electrode with an ultrathin lithium-loving high-entropy alloy interface layer, and belongs to the technical field of lithium metal batteries. The preparation method comprises the following steps: dispersing a carbon nanotube coated high-entropy alloy composite material, lithium tin alloy powder and a hydrophobic polymer in a non-organic solvent, coating a copper foil with the mixture, and drying the copper foil to obtain an ultrathin, pre-lithiated and lithium-loving negative electrode of a high-entropy alloy interface layer. According to the preparation method of the lithium metal negative electrode with the ultrathin lithium-loving high-entropy alloy interface layer, catalytic elements in the high-entropy alloy composite material coated with the carbon nanotubes are used for inducing the carbon nanotubes to form a 3D conductive network framework, so that the current density of the electrode can be effectively reduced, lithium metal deposition can be accommodated, and the lithium metal negative electrode has a good application prospect. And meanwhile, release of lithium ions in the lithium tin alloy can be activated for lithium pre-supplement, so that generation of lithium dendrites and dead lithium is inhibited, the volume change of a lithium metal negative electrode in the charge-discharge cycle process is slowed down, and the cycle stability of the battery is improved.

The invention provides a high-temperature-resistant salt-resistant cross-linked hydrophobic polymer, and belongs to the technical field of hydrophobic polymers. The polymer is prepared by carrying out copolymerization on 2-acrylamido-2-methylpropanesulfonic acid, an alkenyl polycyclic monomer, a divinyl monomer and fluorine-containing short carbon chain acrylic ester, the mass ratio of the 2-acrylamido-2-methylpropanesulfonic acid to the alkenyl polycyclic monomer to the divinyl monomer to the fluorine-containing short carbon chain acrylate is 20: (5-8): (0.5-2): (3-5). The molecular structure of the high-temperature-resistant salt-resistant cross-linked hydrophobic polymer contains a vinyl polycyclic structural unit and a fluorine-containing group which can inhibit thermal degradation of acrylamide under a high-temperature condition, and functional groups such as ester and ether which are easy to degrade at a high temperature do not exist in molecules, so that the high-temperature-resistant salt-resistant cross-linked hydrophobic polymer has good temperature resistance; the aqueous solution viscosity can be kept stable for a long time under a high-temperature condition.

The instant disclosure is drawn to a cosmetic or personal care compositions in the form of oil-in-water dispersions, wherein the dispersion comprises oil droplets having a size from about 10 nm to about 1 μm. The compositions also include: (a) a hydrophobic polymer formed from a reaction product of a natural or food-derived oil and a methacrylate or acrylate polymer; (b) one or more solvents capable of solubilizing the hydrophobic polymer; (c) one or more biosurfactants, and optionally, one or more co-surfactants; and (d) water. Methods for making and using the compositions and methods for boosting foam are also disclosed.

The invention provides a high-modulus low-friction heterogeneous gel material as well as a preparation method and application thereof. The heterogeneous gel material is obtained through the steps that hydrophilic monomers are subjected to free radical polymerization in a hydrophobic polymer solution to obtain a heterogeneous polymer with a hydrophobic phase and a hydrophilic phase in a continuous phase separation structure, then the heterogeneous polymer is swelled, and the mass fraction of the hydrophobic phase in the heterogeneous polymer is 20-50%; the molecular weight of the hydrophobic polymer is 8000 to 50000 Da; wherein the tensile modulus of the heterogeneous gel material is 10 MPa-1 GPa, and the friction coefficient of the heterogeneous gel material under the contact pressure of 1 to 50 MPa is 0.005 to 0.03. The heterogeneous gel material has a bicontinuous phase separation structure, so that the technical problem that the mechanical property and the lubricity of a traditional hydrophilic material are mutually restricted and are difficult to balance can be effectively solved.

The invention discloses a phase-change heat-storage fluffy fiber and a preparation method thereof. According to the method, polyethylene glycol, microcapsules, fatty acid, paraffin or alkane and the like are used as phase change heat storage materials, elastic polymers such as polystyrene, polyurethane, polyamide and the like are used as elastic spinning materials, and hydrophobic polymers such as polyacrylonitrile, polysulfone, polytetrafluoroethylene, polyvinylidene fluoride and the like are used as hydrophobic spinning materials; the phase-change heat-storage fluffy fiber is prepared in a high-humidity environment through an electrostatic spinning method. The phase-change heat-storage fluffy fiber synthesized by the method is in a flexible fluffy form and has the advantages of good phase-change stability, low heat conductivity coefficient and the like, and the environmental temperature is kept stable through an accompanying heat absorption or heat release effect when phase change occurs at the phase-change temperature; the material can be used as a thermal insulation filling material and has wide application prospects in human body and environment thermal management and other aspects.

The invention discloses a ZIF-7-OH surface modified polysulfone composite oil-water separation membrane as well as a preparation method and application thereof. Through simple blending and non-solvent induced phase inversion, the method comprises the following specific steps: firstly, synthesizing a hydrophobic polymer through free radical polymerization, and then blending the hydrophobic polymer with a polysulfone matrix to form a membrane casting solution; secondly, hydroxylated ZIF-7 (ZIF-7-OH) particles are fixed to the surface of the membrane through a non-solvent induced phase inversion method; wherein due to the introduction of hydroxyl, particles and hydrophobic polymers with siloxane groups can be coupled and fixed on the membrane, so that the stability of the particles on the surface of the membrane is improved, and finally, the super-hydrophobic polysulfone composite membrane for efficient oil-water emulsion separation is obtained. The ZIF-7 particles are creatively hydroxylated and fixed to the surface of the membrane through a coupling effect, and the micro-nano rough structure and the low-surface-energy substance have a synergistic effect, so that the membrane is endowed with super-hydrophobicity and excellent self-cleaning performance, and the composite membrane has efficient oil-water emulsion separation capacity.

A sodium secondary battery positive electrode material and a preparation method therefor, a positive electrode sheet, a sodium secondary battery, and an electric device. The sodium secondary battery positive electrode material comprises a sodium-containing positive electrode material and a coating material located on at least part of the surface of the sodium-containing positive electrode material, wherein the coating material comprises a hydrophobic polymer.

The invention belongs to the technical field of fuel cells, and relates to a microporous layer with a humidity self-adjusting function and a preparation method thereof, and the microporous layer with the humidity self-adjusting function is of a hydrophilic and hydrophobic mixed structure and is arranged between a cathode catalyst layer and a cathode gas diffusion layer. Comprising a carbon material, a hydrophobic polymer and a ceramic oxide modified by a sulfonic acid group, the proton exchange membrane fuel cell adopting the microporous layer has a humidity self-adjusting function during working; the preparation method comprises the following steps: uniformly dispersing a carbon material and a ceramic oxide modified by a sulfonic acid group in ethanol and / or isopropanol to obtain a dispersion liquid, adding a water repellent agent into the dispersion liquid, uniformly mixing to obtain a microporous layer slurry, and finally coating the microporous layer slurry on the gas diffusion layer to obtain the gas diffusion layer. And drying at a constant temperature to obtain the microporous layer with the humidity self-adjusting function. With the adoption of the microporous layer, the comprehensive performance and the long-term stability of the fuel cell can be remarkably improved; the preparation method is simple.

The invention discloses wear-resistant plastic particles and a preparation method thereof, and relates to the technical field of plastic particles. Comprising the following raw materials in parts by mass: 70-90 parts of polypropylene, 80-100 parts of polyethylene, 6-8 parts of friction-increasing filler, 1-2 parts of polyol ester, 1-2 parts of calcium stearate, 2-3 parts of polyamide, 1-2 parts of a plasticizer, 1-2 parts of a high-impact-resistance toughening agent, 1-3 parts of a hydrophobic polymer, 2-3 parts of an antioxidant and 2-4 parts of an adhesive. When the plastic particles are manufactured, a mixed substance composed of silicon dioxide, glass fibers, carbon fibers and nano-particles is adopted as a friction increasing filler to be matched with the high-impact-resistance toughening agent, so that the wear resistance of the plastic particles can be effectively improved, and the wear resistance of the plastic particles is improved while the wear resistance is improved. Therefore, the plastic particles have wear resistance and also have various properties such as good flame retardance, supporting property and hydrophobicity.

The invention discloses a carbon-coated nickel-based super-hydrophobic catalyst as well as a preparation method and application thereof, and belongs to the technical field of catalysts and high alcohol synthesis. The preparation method comprises the following steps: dissolving nickel salt and citric acid in water, and then heating and stirring the obtained mixed solution to obtain a precursor; roasting the precursor in an inert atmosphere to obtain a carbon-coated nickel-based catalyst; and carrying out ball-milling mixing on the carbon-coated nickel-based catalyst and polytetrafluoroethylene to obtain the carbon-coated nickel-based super-hydrophobic catalyst. According to the invention, the carbon-coated nickel-based catalyst is firstly prepared, then the carbon-coated nickel-based catalyst is coupled with the hydrophobic polymer polytetrafluoroethylene to form a new super-hydrophobic catalyst, and the nickel-based catalyst and the polytetrafluoroethylene are subjected to ball-milling mixing, so that the hydrophobic property of the nickel-based catalyst is improved, the water poisoning phenomenon of the catalyst is relieved, and further coupling of low-carbon alcohol to higher alcohol is promoted; the yield of the high alcohol and the selectivity of the C6 < + > high alcohol are improved, and the method has a wide application prospect.

An implantable device for delivery of a macromolecular drug compound is provided. The device comprises a core having an outer surface and a membrane layer positioned adjacent to the outer surface of the core. The core comprises a core polymer matrix within which is dispersed a drug compound having a molecular weight of about 5 kDa or more, the polymer matrix containing a hydrophobic polymer. The membrane polymer matrix includes from about 70 wt. % to about 99 wt. % of an ethylene vinyl acetate copolymer.

The invention provides an EICP-based sandy soil curing agent, a sandy soil curing method and application thereof, and relates to the technical field of rock and soil reinforcement. The sandy soil curing agent comprises a urease solution, a cementing fluid and a hydrophobic polymer, wherein the urease solution is prepared by salting out a urease crude extract and then carrying out solid-liquid separation; the cementing liquid comprises calcium salt, magnesium salt and urea. The curing agent is convenient to use, the solidified soil body is stable in structure, and the curing agent has excellent disintegration resistance. The invention further provides a sandy soil curing method and application of the sandy soil curing agent or the sandy soil curing method.

The invention discloses a high-performance Mg < 2 + > / Li < + > separation nanofiltration membrane and a preparation method thereof, the Mg < 2 + > / Li < + > separation nanofiltration membrane is a polymer composite membrane, and is composed of a surface separation layer and a support layer; the surface separation layer is formed by self-assembling a polycation electrolyte and a polyanion electrolyte layer by layer, the supporting layer is formed by ultraviolet grafting of any one or two of sodium polystyrene sulfonate, polymethylacrylic acid 3-sulfonic acid propyl ester potassium salt and polyacrylic acid on the surface of a hydrophobic polymeric membrane, and the surface of the supporting layer is negatively charged. The negative charge amount of the supporting layer is gradually reduced from top to bottom; the whole separation membrane has the characteristics that the upper layer is hydrophilic and the lower layer is hydrophobic. By adjusting the charge density and aperture of the supporting layer, the structure of the surface separation layer is influenced, the charge repulsion effect, aperture screening effect and built-in electric field intensity of the whole membrane are enhanced, and the Mg < 2 + > / Li < + > separation factor is increased. Permeation and rapid transportation of water are promoted by virtue of a hydrophilic upper-layer and hydrophobic lower-layer structure, and the membrane flux is improved; the preparation process is simple, and the used solvent is water, so that the method is green and environment-friendly and has a good application prospect.

The invention relates to a wet response fiber and a preparation method and application thereof. The wet response fiber is a double-component parallel type composite fiber. Wherein the first component comprises a wet response factor and a polymer; the second component includes a hydrophobic polymer. The two components in the two-component wet response fiber material are controllable and adjustable, the driving effect is obvious, the spinning process is simple, continuous preparation can be achieved, various textile processes can be easily matched, and customized wet response textured fabric is achieved. The wet response fiber disclosed by the invention is expected to be used in the fields of intelligent wearing, sports health, medical assistance, high-end equipment, environmental perception, information acquisition, artificial muscles, soft robots and the like.

The invention discloses an SERS (Surface Enhanced Raman Scattering) substrate for nano plastic detection based on metal nanoparticle domain aggregation and a preparation method of the SERS substrate, and belongs to the technical field of nanomaterial science and optical analysis. And the two layers of noble metal nanoparticles are successively deposited in a designated area of the hydrophilic microporous polymer film through suction filtration to obtain the nano plastic detection SERS substrate. According to the present invention, the hydrophilic and hydrophobic polymer film and the microporous structure thereof are utilized to sequentially aggregate the silver nanoparticle domains with different sizes to the surface of the hydrophilic polymer film, such that the high-sensitivity detection of the nano-plastic in the aqueous solution is achieved, and the problem of the large nano-plastic detection difficulty caused by the small size is overcome;

A method of stimulating a subterranean formation includes preparing an aqueous dispersion including one or more cellulosic nanoparticles. The cellulosic nanoparticles have respective surfaces functionalized with one or more hydrophilic polymers or ligands. one or more hydrophobic polymers or ligands, or a combination thereof. The method also includes pumping the aqueous dispersion into the subterranean formation.

The invention discloses a halide solid electrolyte with a multilayer hierarchical core-shell structure, which sequentially comprises an inner core halide solid electrolyte, a first conductive polymer high-molecular coating layer and a second hydrophobic polymer high-molecular coating layer from inside to outside, the first conductive polymer high-molecular coating layer is formed by copolymerizing conductive polymer monomers with ether oxygen groups-O-or carbonyl C = O, and the second hydrophobic polymer high-molecular coating layer is prepared by ball-milling, sintering and coating a high-molecular hydrophobic material on the surface of the first conductive polymer high-molecular coating layer; and a chemical bonding interface is formed between the first conductive polymer high-molecular coating layer and the inner core halide solid electrolyte through an ether oxygen group-O-or carbonyl C = O in a molecular chain segment. The thickness of the prepared halide solid electrolyte membrane can be reduced to be less than 100 microns, the growth of lithium dendrites is inhibited by the interface self-adaptive characteristic, and the capacity retention rate is gt after 200 cycles; 80%; the sintering temperature is less than or equal to 300 DEG C, the energy consumption is reduced, and lattice distortion is avoided.

According to the sodium lipoate-based agglomerate biological adhesive and the preparation method thereof, the local concentration of sodium lipoate in the agglomeration process is improved, so that a five-membered ring disulfide bond of sodium lipoate can be opened to initiate a polymerization reaction, and a strong bidentate salt bridge hydrogen bond can be formed between sodium polylipoate and guanidyl monomer molecules to effectively reduce the potential energy of a system; therefore, the aggregate can be stable for a long time at room temperature and can form a transparent amorphous patch after the solvent is volatilized. Based on the hydrophobicity of a condensation body, the mobility of a polymer chain and abundant guanidyl and carboxylate radical groups on a skeleton of the condensation body, the adhesive can realize long-term stable adhesion to wet tissues such as skin and the like.

To provide a gel preparation kit, a gel preparation material, a medicinal drug, and a medical device that suppress a reaction with a medicine or a cell, and promote inclusion of a hydrophobic medicine into the gel or cell proliferation.SOLUTION: A gel preparation kit comprising a polymer (A) and a polymer (B), where the polymer (A) includes a hydrophilic polymer portion (A1) with 2 to 8 branches, a hydrophobic polymer portion (A2) that is bonded to the side chains or ends of each branch of the hydrophilic polymer portion (A1), and a click-reactive group (A3) that is bonded to at least one side chain or end of the hydrophobic polymer portion (A2), and polymer (B) includes a hydrophilic polymer portion (B1) with 2 to 8 branches, a hydrophobic polymer portion (B2) that is bonded to the side chains or ends of each branch of the hydrophilic polymer portion (B1), and a click-reactive group (B3) that is bonded to at least one side chain or end of the hydrophobic polymer portion (B2). The click-reactive groups (A3) and (B3) can be cross-linked through a click reaction.SELECTED DRAWING: None

Mineral sunscreen compositions are described, having (a) a hydrophobic polymer formed as a reaction product of a natural or food-derived oil and a methacrylate or acrylate polymer; (b) one or more solvents capable of solubilizing the hydrophobic polymer; (c) one or more mineral UV filtering agents; (d) one or more surfactants; and (e) water; wherein the composition is an oil-in-water emulsion. Methods from making and using the mineral sunscreen compositions are also described.

The invention relates to a microflow control preparation method of leuprorelin acetate microspheres, which comprises the following steps: (1) dissolving a hydrophilic-hydrophobic polymer in an organic solvent, adding a leuprorelin acetate aqueous solution, stirring, evaporating and self-assembling for 30 + / -15 minutes to form a W / O type polymer microemulsion; (2) adding the polymer microemulsion into the pregel component, stirring, mixing and volatilizing for 1-2 hours, and removing the organic solvent to form a microgel precursor; and (3) taking the solution in the step (2) as a dispersion phase A, the pre-gel component as a dispersion phase B and fluorinated oil containing 2% of a surfactant Pico-Surf as a continuous phase to be connected into a micro-droplet generation system to generate monodispersed micro-droplets, and performing cross-linking curing, washing out and freeze-drying to obtain the leuprorelin acetate microspheres. The prepared microspheres are uniform in size and good in quality consistency, have the advantages of being high in encapsulation efficiency and drug loading capacity, controllable in drug sustained release, free of obvious burst release and the like, and are more suitable for meeting clinical requirements.

This disclosure relates to polyethylene glycol (PEG)-functionalized nanoparticles comprising a functional agent, and preparation methods, properties and applications thereof. The nanoparticle represented by PEG-L-G / P, comprising a type of hydrophilic PEG, a hydrophobic functional agent G, which are covalently linked by L: a linker or a chemical bond, and a type of hydrophobic polymer P. The G and P form the hydrophobic core, while the PEG constitutes the hydrophilic outer layer of the nanoparticle in an aqueous medium. The functional agent comprises one or more functional compounds including a therapeutic drug, an imaging diagnostic agent, a photoelectric responsive diagnostic agent, an immune-stimulating agent, or a combination thereof. The nanoparticles comprising such functional agent can offer various applications in multiple biomedical fields.

The invention relates to the technical field of sewage treatment, and particularly discloses a high-porosity slow-release microelement anti-mineralization sulfur autotrophic denitrification filter material and a preparation method thereof. The sulfur autotrophic denitrification filter material is of a core-shell structure, a complex of sulfur, volcanic rock micro powder and a curing fungicide is used as an inner core, and a hydrophobic polymer coating layer and a porous ceramic bonding layer are sequentially coated on the surface of the inner core; the hydrophobic polymer coating layer is a hydrophobic breathable composite film formed by crosslinking a polydimethylsiloxane prepolymer and calcium alginate. The volcanic rock natural trace elements are utilized to realize waste control by waste, surface mineralization is effectively prevented through the hydrophobic middle layer, the activity of the microbial inoculum is protected in combination with a low-temperature flexible sintering process, and the whole device has the advantages of high porosity, light weight, quick start, long service life, low backwashing energy consumption and the like. Compared with the prior art, the invention has remarkable innovativeness and creativity in the aspects of structural design, material selection and process integration.

This disclosure relates to polyethylene glycol (PEG) -functionalized nanoparticles comprising a functional agent, and preparation methods, properties and applications thereof. The nanoparticle represented by PEG-L-G / P, comprising a type of hydrophilic PEG, a hydrophobic functional agent G, which are covalently linked by L: a linker or a chemical bond, and a type of hydrophobic polymer P. The G and P form the hydrophobic core, while the PEG constitutes the hydrophilic outer layer of the nanoparticle in an aqueous medium. The functional agent comprises one or more functional compounds including a therapeutic drug, an imaging diagnostic agent, a photoelectric responsive diagnostic agent, an immune-stimulating agent, or a combination thereof. The nanoparticles comprising such functional agent can offer various applications in multiple biomedical fields.

The invention relates to the technical field of composite biological coatings. Specifically, the invention relates to a hydrophobic composite layer on a medical degradable magnesium alloy matrix and a preparation method of the hydrophobic composite layer. In the preparation method, firstly, a porous ceramic oxide layer is formed on a magnesium alloy matrix through micro-arc oxidation treatment, so that the corrosion rate of the magnesium alloy is reduced; then, a strontium-doped hydroxyapatite layer is prepared on the surface of the micro-arc oxidation layer by using a chemical deposition method, so that the biocompatibility of the magnesium alloy is improved; and finally, dipping and pulling the magnesium alloy subjected to micro-arc oxidation and chemical deposition treatment in a polylactic acid solution containing nano-hydroxyapatite for one time or multiple times, so as to form a hydrophobic polymer layer. According to the hydrophobic composite layer prepared by the method, the corrosion resistance and the biocompatibility of the magnesium alloy are improved at the same time. The invention also relates to a magnesium alloy implant article comprising the hydrophobic composite layer.

The invention discloses a medical pressure-sensitive adhesive patch based on citric acid, a preparation method and application, the medical pressure-sensitive adhesive patch is composed of an adhesion layer and an anti-adhesion layer, and the thickness ratio of the adhesion layer to the anti-adhesion layer is 1: 1-100: 1; the adhesion layer is obtained by polymerizing a citric acid unit and a polyhydroxy compound unit; the hydrophobic high-molecular polymer is selected from at least one of a polylactic acid-glycolic acid copolymer, polylactic acid, polyurethane and polyether urethane. According to the preparation method, three carboxyl groups in the citric acid not only can be used for esterification reaction with polyhydric alcohols to form a network, but also can provide excellent adhesive force for contact between the adhesive patch and the tissue surface through electrostatic interaction or hydrogen-bond interaction. The anti-sticking layer prepared from the hydrophobic high-molecular polymer can effectively resist invasion of external moisture and bacteria, so that the service time of the adhesive patch is prolonged; meanwhile, the anti-sticking layer can also play a supporting role, so that the mechanical strength of the adhesive tape is improved.