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40 results about "Triclosan" patented technology

Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.

Bacterial culture medium for producing algin through liquid fermentation

The invention discloses a bacterial culture medium for producing algin through liquid fermentation. The bacterial culture medium contains triclosan and SDS (Sodium Dodecyl Sulfate). Tests show that the PIB culture medium added with triclosan and SDS can improve the capability of producing algin by PFAC-PAO1 liquid fermentation. Accordingly, the inventor develops innovative research of optimizing the culture medium, the ChinaYin culture medium is finally obtained, and the specific formula of the ChinaYin culture medium is as follows: 20g / L of tryptone, 1.4 g / L of magnesium chloride, 10g / L of potassium sulfate, 20mL / L of glycerol, 50mu g / mL of triclosan and 125mu g / mL of SDS (Sodium Dodecyl Sulfate). Researches show that by applying the culture medium, the polysaccharide yield is higher than that of a PIB culture medium and a USAYu culture medium, the yield in 48 hours is higher than that of 24 hours and 72 hours, the yield of algin powder obtained in each culture bottle can reach 8 g / L, and it is indicated that the ChinaYin culture medium has the potential of being industrially amplified to be used for fermentation production of bacterial algin.
Owner:GUANGXI UNIV

Medical sterile ultrasonic coupling agent and preparation method thereof

PendingCN120860266AAntibacterial agentsAntisepticsTriclosanMedicine
The invention relates to the technical field of medical coupling agents, and discloses a medical sterile ultrasonic coupling agent which comprises the following components: carbomer, a humectant, a quaternary ammonium salt disinfectant, a preservative, a pH regulator and purified water. A preparation method of the medical sterile ultrasonic coupling agent comprises the following steps: step 1, dispersing the carbomer in part of purified water, stirring until the carbomer is completely swelled, adding the preservative and the pH regulator, and continuously stirring for 20 minutes; step 2, dissolving a quaternary ammonium salt disinfectant and a humectant in the residual purified water, uniformly mixing, adding into the gel in the step 1, and vacuumizing and stirring for 10 minutes; and step 3, performing irradiation sterilization after filling to obtain a finished product. Compared with the prior art, the invention has the advantages that: the quaternary ammonium salt is used for replacing triclosan, so that skin irritation and environmental pollution are avoided, and the safety is high. A solubilizer is not needed, and the production process is simplified. According to the invention, the compatibility problem of quaternary ammonium salt and carbomer is solved through a special process, and the stability and viscosity of the product are ensured.
Owner:SHANDONG JIUER IND GRP CO LTD

Biomarkers for predicting the risk of prostate cancer caused by triclosan and applications thereof

PendingCN122326750ATriclosanProstate cancer
This invention relates to biomarkers and their applications for predicting the risk of prostate cancer induced by triclosan, belonging to the fields of environmental health and tumor biology. This invention systematically identifies oncogenes CHRM5, PLK1, ALB, and TOP2A associated with triclosan exposure and constructs a predictive model for the risk of prostate cancer induced by triclosan using machine learning methods. Therefore, this invention provides novel biomarkers and potential therapeutic targets for predicting the risk of prostate cancer induced by triclosan.
Owner:GUANGZHOU FIRST PEOPLES HOSPITAL (GUANGZHOU DIGESTIVE DISEASE CENT GUANGZHOU FIRST PEOPLES HOSPITAL GUANGZHOU MEDICAL UNIV THE SECOND AFFILIATED HOSPITAL OF SOUTH CHINA UNIV OF TECH)

sutures

PendingEP4670747A2Suture equipmentsTriclosanDrug content
The invention relates to a suture thread material comprising at least one polymer and at least one eutectic mixture. The polymer can be a biocompatible polymer such as polycaprolactone or PLGA. The eutectic mixture comprises triclosan. Other eutectic mixtures can be used in suture thread materials to reduce SSis and / or to decrease pain and / or to increase lubricity of sutures. The invention also provides a method for the production of sutures with drug loadings, the method comprising the use of therapeutic deep eutectic solvent (THEDES) technology to significantly increase drug content in suture matrices.
Owner:QUEENS UNIV OF BELFAST

High-temperature-resistant functional food preservation bag and manufacturing method thereof

PendingCN121378932AContainers preventing decayTriclosanPolypropylene
The invention relates to the technical field of food fresh-keeping bags, and discloses a high-temperature-resistant functional food fresh-keeping bag and a manufacturing method thereof.The food fresh-keeping bag is obtained by taking polyethylene as a base material and taking a high-temperature-resistant modifier, hydroxyapatite antibacterial filler and the like as auxiliary materials through mixing, extrusion, film blowing and bag manufacturing, the high-temperature-resistant modifier contains hydroxyl and a hindered phenol antioxidant structure, and acts with the compatilizer through melt blending, so that the high-temperature-resistant performance of polyethylene is improved, polypropylene is endowed with oxidation resistance, and the problem of oxygen aging is avoided; the hydroxyapatite antibacterial filler is prepared by grafting the triclosan on the hydroxyapatite, the dispersity of the hydroxyapatite is improved through grafting, the strength and toughness of the polyethylene can be effectively improved through uniform dispersion, and the triclosan has broad-spectrum antibacterial property and endows the polyethylene with antibacterial property.
Owner:DONGGUAN ZHENGLI PACKAGING MATERIALS CO LTD

A hydrolysis device for producing triclosan

ActiveCN224686891UBiotechnologyTriclosan
The utility model discloses a kind of hydrolysis devices for producing triclosan, including hydrolysis reactor, hydrolysis reactor;Hydrolysis reactor is equipped with stirring mechanism, and stirring mechanism includes stirring shaft, spiral stirring vane, stirring motor interface, spiral stirring vane is also equipped with multiple non-parallel setting auxiliary stirring vane, spiral stirring vane and auxiliary stirring vane are equipped with turbulence hole;The bottom of stirring shaft is equipped with buffer cavity, and buffer cavity is communicated with the hollow stirring rod of being arranged in the lower portion of stirring shaft, and the main gas outlet hole is equipped on the hollow stirring rod;The bottom of stirring shaft is communicated gas pipeline by swivel joint;The inner wall of hydrolysis reactor is equipped with annular array ultrasonic transducer.This device guarantees that hydrolysis reaction is carried out fully, avoids the occurrence of side reaction, improves the production efficiency of product, and tail gas produced in hydrolysis process is fully treated, avoids its pollution to environment.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

A method for treating a triclosan antibacterial coating on sutures

ActiveCN120586140BSuture equipmentsCoatingsBiotechnologyTriclosan
The present application relates to the technical field of antibacterial coating, in particular to a processing method of triclosan antibacterial coating for suture, and the specific steps are as follows: S1, preparation of moxa tablet-triclosan antibacterial solution; S2, preparation of moxa tablet-triclosan spraying solution; S3, suture pretreatment; S4, suture spraying.The present application has the following beneficial effects: 1. Good versatility: the suture with moxa tablet-triclosan antibacterial coating prepared by the present application is sprayed by ultrasonic spraying machine, and the same production process is used for different suture materials and single or multi-strand sutures, so that the production cost is greatly reduced, and the development of enterprises is facilitated; 2. Broad-spectrum bacteriostasis: the suture has good bacteriostatic rate for staphylococcus aureus, escherichia coli and stenotrophomonas maltophilia; 3. Low allergenicity.
Owner:NANJING JUANRUN MEDICAL TECH CO LTD

A functional fiber membrane for bacterial visual monitoring and response antibacterial and its preparation method and use

ActiveCN118087155BTriclosanFiber
The application provides a functional fiber membrane for bacterial visual monitoring and response antibacterial and a preparation method and application thereof, and belongs to the field of biological medical materials. The functional fiber membrane is a fiber membrane with a double-layer structure. A lower membrane of the fiber membrane is prepared from TCS@ZIF-8 nanoparticles and poly-epsilon-caprolactone as raw materials. An upper membrane of the fiber membrane is prepared from poly-epsilon-caprolactone, polyethylene glycol and bromo-musk toluene phenol blue as raw materials. The TCS@ZIF-8 nanoparticles are prepared from the following raw materials in a weight ratio: zinc nitrate hexahydrate 1-5 parts, triclosan 1-5 parts and 2-methyl imidazole 1-5 parts. The functional fiber membrane can realize naked-eye monitoring of various bacteria in a short time, has high monitoring sensitivity and can meet the clinical diagnosis requirements. Meanwhile, the membrane has excellent antibacterial performance and can synergistically antibacterial with photocatalysis. The functional fiber membrane has a simple preparation process, is convenient to operate and is convenient to carry, provides a feasible scheme for bacterial monitoring and has application prospects.
Owner:SICHUAN UNIV +3

A ratiometric fluorescent probe for detecting triclosan based on metal-organic framework materials and its preparation and application

The present invention relates to a ratiometric fluorescent probe for detecting triclosan based on a metal-organic framework material, and its preparation and application. The fluorescent probe is prepared by the following method: UiO-67-bpy powder is first reacted with EuCl3 to generate Eu@UiO-67-bpy, which is then reacted with CDs to obtain a pale yellow Eu / CDs@UiO-67-bpy solid powder, which is the target product. Compared with the prior art, the fluorescent probe of the present invention can detect triclosan with ultrafast response speed, excellent selectivity, good anti-interference ability, high sensitivity, no interference from environmental factors, and higher accuracy without the need for tedious pretreatment and professional operation, and can still have excellent selectivity for triclosan in the presence of other organic substances with similar structures to triclosan.
Owner:SHANGHAI NORMAL UNIVERSITY

Antimicrobial cyanoacrylate formulations

PendingUS20260115350A1Surgical adhesivesTriclosanPolymer science
Described herein are polymerizable compositions useful as surgical adhesives, where the compositions include at least one antimicrobial agent dissolved in a cyanoacrylate monomer, where the at least one antimicrobial agent includes a cinnamon derivative comprising at least one of cinnamaldehyde, a cinnamic ester, a cinnamon essential oil, and where the at least one antimicrobial agent optionally further includes triclosan or a derivative thereof and / or povidone iodine. The antimicrobial agent is soluble in and compatible with the cyanoacrylate monomer.
Owner:CHEMENCE MEDICAL

Application of compound triclosan in preparation of medicine for treating toxoplasmosis

The invention discloses application of a compound triclosan in preparation of a medicine for treating toxoplasmosis. The medicine is used for inhibiting toxoplasmosis proliferation. The medicine is used for relieving pathological injuries of one or more organs caused by toxoplasma gondii infection, and the organs comprise the heart, the liver, the spleen, the kidney and the brain. The medicine is used for protecting brain tissues or penetrating a blood brain barrier to treat toxoplasma gondii infection of a central nervous system; the medicine comprises a therapeutically effective amount of triclosan and a pharmaceutically acceptable carrier or auxiliary material, the dosage form of the medicine is an oral preparation; the application has the beneficial effects that the broad-spectrum antibacterial agent triclosan is proved to have a new application of remarkably treating toxoplasmosis for the first time, in-vivo and in-vitro experiments prove that triclosan can effectively inhibit the proliferation of toxoplasmosis, the effect is dose-dependent, and in an acute infection mouse model, triclosan can remarkably improve the survival rate of mice and reduce the ascites insect-bearing quantity, so that the effect of treating toxoplasmosis is achieved. The pathological injury of multiple organs such as heart, liver, spleen and kidney can be relieved.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS +1

A compound traditional Chinese medicine detoxification ointment and a preparation method thereof

This invention discloses a compound traditional Chinese medicine detoxifying ointment and its preparation method. The compound traditional Chinese medicine detoxifying ointment comprises a traditional Chinese medicine extract, triclosan, a gel matrix, a cooling and antipruritic agent, a moisturizer, a surfactant, a pH adjuster, and purified water. The traditional Chinese medicine extract is prepared by a group extraction process using five medicinal slices—honeysuckle, scutellaria, coptis, rhubarb, and corydalis—in a specific ratio: honeysuckle, scutellaria, and corydalis form the first group, while coptis and rhubarb form the second group. These are extracted separately by ethanol reflux extraction and microfiltration purification, then a colloidal dispersion system is formed using a pH segmented control method, followed by concentrating the extracts. This invention, through the synergistic combination of the traditional Chinese medicine extract, low-concentration triclosan, and the cooling and antipruritic agent, enables the product to possess multiple effects, including highly effective broad-spectrum antibacterial properties, cooling and antipruritic effects, and blood-activating and analgesic effects. Furthermore, it is non-irritating to the skin, exhibits good stability, and is suitable for industrial production.
Owner:HANGZHOU CHILDRENS HOSPITAL +1

Self-adaptive phase-change microstructure antibacterial antifouling coating as well as preparation method and application thereof

The invention discloses a self-adaptive phase-change microstructure antibacterial antifouling coating as well as a preparation method and application thereof. The method comprises the following steps: (1) synthesizing a bacteriostatic active silane functional element; (2) synthesizing a phase change type active silane functional element; (3) synthesizing antibacterial organic silicon resin with a phase change function; and (4) preparing the composite array microstructure antibacterial antifouling coating. The preparation method comprises the following steps: firstly constructing a triclosan and / or coumarin-based synergistic antibacterial element, then preparing a long-chain alkyl phase-change functional element, then preparing organic silicon resin through polycondensation, and finally compounding the organic silicon resin with a nano filler, and molding to obtain the array microstructure coating. Under high temperature or strong light, the modulus of the microstructure coating is reduced, large-amplitude swing is generated, and contamination attachment is inhibited; in a low-temperature or dark environment, the modulus is increased, the microstructure is stable, and the durability is improved. A phase change driven modulus regulation and control mechanism is coupled with antibacterial elements, microstructures and low surface energy characteristics of organic silicon, so that self-adaptive antifouling in a complex environment is realized.
Owner:QUZHOU RES INST OF ZHEJIANG UNIV

Method for producing amino water reducer by using triclosan etherification wastewater extract

The invention relates to the technical field of industrial wastewater, in particular to a method for producing an amino water reducing agent by using triclosan etherification wastewater extract, which comprises the following steps: (1) taking collected triclosan etherification wastewater, adjusting the pH value to be acidic, layering, and collecting upper-layer extract and lower-layer wastewater; (2) taking lower-layer wastewater, adding an extracting agent, stirring, and concentrating and crystallizing the collected lower-layer potassium chloride solution to obtain a potassium chloride product; an upper-layer extract and condensate water are reserved for use; and (3) taking condensate water, adding phenol, sodium sulfanilate, the upper-layer extract and the upper-layer extract, stirring, adjusting the pH value to be alkaline, heating, dropwise adding formaldehyde, continuously heating for reaction, cooling, adjusting the pH value, and adding water to adjust the solid content, thereby obtaining the amino water reducer. According to the method, zero discharge of the triclosan etherification waste liquid is realized, the current pollution situation of the phenol-containing waste water is effectively improved, the environment is protected, the triclosan etherification waste water is comprehensively utilized, and the method has good economic benefits and environmental protection benefits.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

Bacteriostatic nursing gel with immunity enhancing effect and preparation method thereof

The invention discloses antibacterial nursing gel with an immunity enhancing effect and a preparation method thereof. Comprising the following raw materials in parts by weight: 0.5 to 3 parts of carbomer, 0.5 to 3 parts of triethanolamine, 80 to 94 parts of purified water, 0.1 to 1 part of chitosan, 0.01 to 0.1 part of triclosan, 0.1 to 0.3 part of phenoxyethanol, 0.5 to 5 parts of a radix stemonae extract, 0.01 to 0.5 part of a saffron crocus extract, 0.5 to 3 parts of a cortex phellodendri extract, 0.5 to 3 parts of a fructus cnidii extract and 0.5 to 3 parts of a radix sophorae flavescentis extract. The prepared gel product is suitable for treating or preventing skin and mucous membrane infection, inflammation and related symptoms, meanwhile, the immune function can be adjusted, the body resistance is improved, and comprehensive protection is provided for female health.
Owner:GUANGZHOU SAIMEI PHARM CO LTD

A device for preparing triclosan

ActiveCN224405096Uincrease profitResidue reductionXylyleneTriclosan
The utility model discloses a triclosan preparation device relates to triclosan production technical field, including first reactor, the inlet of first reactor is respectively through pipeline intercommunication with 2,4 - dichlorophenol jar, sodium hydroxide solution jar, xylene jar I and tetrabutyl ammonium bromide jar, the outlet of first reactor is through pipeline intercommunication with second reactor, the inlet of second reactor is respectively through pipeline intercommunication with 2 - chloro - 5 - nitrobenzene methyl ether jar, dilute hydrochloric acid solution jar, ZnCl2 - Al2O3 solid acid jar, nano TiO2 jar and xylene jar II, the outlet of second reactor is through pipeline intercommunication with third reactor, the inlet of third reactor is through pipeline intercommunication with acetic acid jar, the top gas phase export of third reactor is through pipeline intercommunication with first condenser, and the outlet of first condenser is through pipeline intercommunication with crude product jar, improves the yield of product.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

Formulation

ActiveUS12599555B2Organic active ingredientsAerosol deliveryTriclosanNedocromil Sodium
A composition, for example an oil-in-water emulsion, comprising an amphoteric surfactant, alkoxylated cetyl alcohol, a polar dmg and a preservative, wherein the total amount of preservative present in the composition is about 0.2% w / w or less and is not benzyl alcohol and / or triclosan. The drug may be sodium cromoglicate and / or nedocromil sodium. The formulation may be useful in the treatment of skin diseases such as atopic dermatitis.
Owner:HEWLETT HEALTHCARE LTD

Dental implant, surface treatment method thereof and composite material for dental implant

PendingCN121466370ATissue regenerationCoatingsTriclosanSilicic acid
The invention relates to the technical field of dental implants, in particular to a dental implant, a surface treatment method of the dental implant and a composite material for the dental implant. The surface treatment method of the dental implant comprises the following steps: uniformly mixing zirconium oxide, tricalcium phosphate, monocalcium phosphate, tricalcium silicate, calcium hydroxide, triclosan and polyethylene glycol according to a preset proportion to obtain an initial mixture; grinding the initial mixed material to obtain a composite material; carrying out sand blasting-acid etching treatment on the cleaned and pretreated dental implant, and cleaning and drying; and coating the surface of the cleaned and dried dental implant with the composite material to finish surface treatment. According to the treatment method, the antibacterial property and hydrophilicity of the dental implant can be improved.
Owner:CHANGZHOU SIFARY MEDICAL TECH CO LTD

Skin antibacterial gel and preparation method thereof

The invention relates to the technical field of external medicine preparations, discloses skin antibacterial gel and a preparation method thereof, and aims to solve the technical problems that in the prior art, extraction of multi-polar active ingredients of Mongolian medicine is insufficient, and when natural extracts and chemical bacteriostatic agents are compounded, uneven dispersion, high irritation and poor stability are prone to occurring. The skin antibacterial gel is composed of Mongolian medicine extract, polyvinyl alcohol, xanthan gum, triclosan, glycerin, nicotinamide and other auxiliary materials. The preparation method is characterized in that the Mongolian medicine is extracted by adopting a gradient process combining ultrasonic water extraction and microwave alcohol extraction, so that active ingredients with different polarities are fully reserved; the triclosan is subjected to composite microencapsulation treatment through a trehalose and sodium hyaluronate compounded wall material; according to the preparation method, polyvinyl alcohol and xanthan gum are used for constructing an interpenetrating network matrix, laurocapram is introduced for optimizing the transdermal performance, the Mongolian medicine ingredient extraction efficiency is improved, and the obtained gel is reliable in antibacterial effect, stable in long-term storage performance, low in skin irritation and capable of meeting the skin antibacterial nursing requirement.
Owner:ORDOS MONGOLIAN MEDICINE HOSPITAL (ORDOS MONGOLIAN MEDICINE RES INST)

Cashmere scarf with antibacterial property and preparation method thereof

The invention relates to the technical field of wool scarves, and discloses an antibacterial cashmere scarf and a preparation method thereof.The preparation method includes the following steps of pretreatment of high-quality cashmere, blending of antibacterial fibers, spinning, weaving, antibacterial after-treatment and finished product detection.The surface of the scarf is provided with antibacterial-treated real silk embroidery decorative threads; silver zeolite antibacterial agents are loaded on the real silk threads through an impregnation method, the edge of the scarf is of a special edge covering structure and comprises a built-in antibacterial fiber woven belt and a medical grade antibacterial silica gel edge sealing strip, and the silica gel edge sealing strip contains 3%-5% of triclosan antibacterial agents. Through a dual protection mechanism of fiber embedded antibacterial and surface antibacterial finishing, the problem that a single antibacterial mode is easy to lose efficacy is solved, a synergistic antibacterial effect is generated through compounding of nano-silver and chitosan, and then an antibacterial agent and fibers are firmly combined through a special after-finishing process, so that the antibacterial effect is good. Therefore, the long-acting antibacterial and washing-resistant effects are achieved through multiple antibacterial synergistic effects.
Owner:JIANGSU XINKAISHENG ENTERPRISE DEV

Bacteriostatic polypeptide and application thereof in preparation of pet shower gel

The application discloses a kind of bacteriostatic polypeptide and its preparation pet shower gel application, belong to bacteriostatic polypeptide technical field.The bacteriostatic polypeptide includes the following weight parts of raw materials: glycerol 2-5 parts, plant polypeptide 3-5 parts, sorbitol 20-40 parts, carboxymethyl cellulose 1-2 parts, xanthan gum 0.5-1 part, sodium methyl hydroxybenzoate 2-5 parts, surfactant 0.5-1 part, chlorhexidine 0.5-1 part, triclosan 0.05-0.3 part, deionized water 100 parts;The bacteriostatic polypeptide prepared in the application can be applied in the preparation process of pet shower gel, and has good bacteriostatic performance.
Owner:SUKOTONG BIOTECHNOLOGY (TAIZHOU) CO LTD

Finishing method for improving washability and mildew resistance of textile fabric

PendingCN121087784AFibre typesBiotechnologyTriclosan
The invention discloses a finishing method for improving washability and mildew resistance of a textile fabric. The finishing method provided by the invention comprises the following steps: treating the textile fabric by using an aqueous solution containing a mildew preventive; the mildew preventive is selected from one or more of triclosan, parachlorometaxylenol and 1, 2-benzisothiazolin-3-one, and the mildew preventive is selected from one or more of the following components; the pH value of the aqueous solution containing the mildew preventive is 8.0-9.5. After the textile fabric is treated by the finishing method provided by the invention, the textile fabric not only has excellent mildew-proof performance, but also has good fastness to washing, is suitable for products with high washing frequency for home textiles and outdoor wearing equipment, effectively prolongs the service life of the textile fabric product, and improves the health safety. Meanwhile, reagents used in the method are wide in source and easy to obtain, the preparation process is simple, the cost is relatively low, and the method is suitable for mass production of enterprises.
Owner:BEIJING CTA NEW CENTURY BIOTECH +1

Lysozyme and BZK-based degerming and acarus-killing laundry detergent and preparation method thereof

The degerming and acarus killing laundry detergent based on lysozyme and BZK is prepared from the following raw materials in percentage by mass: 0.01 to 0.5 percent of lysozyme, 0.01 to 1.0 percent of BZK benzalkonium chloride, 0.02 to 1.5 percent of triclosan, 0.01 to 1.5 percent of chelating agent, 12 to 35 percent of composite surfactant, 0.01 to 0.5 percent of protease, 0.01 to 0.5 percent of lipase, 0.05 to 2.0 percent of modified cellulose derivative, 0.01 to 1.5 percent of pH regulator and the balance of deionized water. According to the invention, the lysozyme can synergistically remove bacteria and mites, the effect is remarkable, after the lysozyme destroys bacterial cell walls, the BZK and the triclosan can quickly kill residual microorganisms, the 20-min bacteriostasis rate on escherichia coli, staphylococcus aureus and candida albicans is greater than or equal to 99.9% aiming at mite body surface penetration, the mite removal rate is greater than or equal to 99.9%, and the problem that the effect of a single component is limited is solved.
Owner:WEIBULO DAILY NECESSITIES (GUANGDONG) CO LTD

Ultrathin films for triclosan transfer to metal medical devices

ActiveUS12446933B2Liquid surface applicatorsEther/acetal active ingredientsTriclosanInhibition zone
Provided are orthopedic implants and systems and kits containing orthopedic implants that include biodegradable polymer thin films containing an antimicrobial agent, wherein the implants produce an effective zone of inhibition around a periphery of the surface of the implant and do not produce a loss of release torque between interlocking implant components.
Owner:DEPUY SYNTHES PROD INC

Disinfectant containing plant extract and preparation method thereof

The invention discloses a disinfectant containing plant extracts and a preparation method of the disinfectant. The core of the disinfectant is that a honeysuckle extract, a scutellaria baicalensis extract, a coptis chinensis extract, a rheum officinale extract and triclosan are compounded through a nano-loading technology and placed in a gel matrix to form a slow-release system. The preparation method comprises the following steps: performing HPLC quantitative monitoring on the plant active ingredients; the triclosan and the nano-carrier are processed into a nano-carrier with the average particle size smaller than or equal to 100 nm through technologies such as high-pressure homogenization; and mixing the components with the gel base material, and stabilizing the pH value of the system at 5.5-6.5 by using a pH regulator. The disinfectant disclosed by the invention realizes rapid and broad-spectrum killing of gram-positive bacteria, gram-negative bacteria and fungi by virtue of a synergistic effect of multiple components, and has lasting antibacterial ability by virtue of a nano slow-release effect. The pH value of the product is close to the skin, and the product is detected to be in a non-irritating level and has the advantages of good stability, high safety and suitability for mothers and infants.
Owner:HANGZHOU XIZI SANITARY DISINFECTION MED MASCH CO LTD

A skin bacteriostatic gel and a preparation method thereof

The application relates to the technical field of external drug preparations, and discloses a skin bacteriostatic gel and a preparation method thereof, and aims to solve the technical problems that in the prior art, Mongolian medicine multi-polar active ingredient extraction is insufficient, and when natural extract and chemical bacteriostatic agents are compounded, uneven dispersion, strong irritability and poor stability are prone to occur. The skin bacteriostatic gel is composed of Mongolian medicine extract, polyvinyl alcohol, xanthan gum, triclosan, glycerol, nicotinamide and other auxiliary materials; and the key of the preparation method is that: the Mongolian medicine is extracted by adopting a gradient process combining ultrasonic water extraction and microwave alcohol extraction, so that different polar active ingredients are fully reserved; triclosan is subjected to compound micro-capsulation treatment by being compounded with trehalose and sodium hyaluronate wall materials; an interpenetrating network matrix is constructed by using polyvinyl alcohol and xanthan gum, and laurocapram is introduced to optimize the transdermal performance, so that the extraction efficiency of the Mongolian medicine components is improved; the obtained gel has reliable bacteriostatic effect, stable long-term storage performance and low skin irritability, and can meet the skin bacteriostatic care demand.
Owner:ORDOS MONGOLIAN MEDICINE HOSPITAL (ORDOS MONGOLIAN MEDICINE RES INST)

Production system for triclosan diazonium reaction process

The utility model relates to the technical field of triclosan production, in particular to a production system for a triclosan diazonium reaction process, which comprises an amino sulfate reaction kettle, a discharge port of the amino sulfate reaction kettle is communicated with a heat exchanger, and a discharge port of the heat exchanger is communicated with a first feed port of a tubular static mixer. The nitrosyl sulfuric acid conveying pipeline is communicated with a second feed port of the tubular static mixer, a discharge port of the tubular static mixer is communicated with a feed pipe of the tubular reactor, the feed pipe is provided with an external circulation inlet, and a discharge pipe of the tubular reactor is respectively communicated with the external circulation inlet and the dilution kettle. According to the production system, amino sulfate is prepared in advance through the amino sulfate reaction kettle, part of reaction heat is diluted in one step, the risk of concentrated release of the reaction heat is reduced, and the production safety is improved. The tubular reactor is adopted, so that the reaction time is shortened, side reactions are reduced, the reaction controllability and the reaction yield are improved, and the subsequent post-treatment difficulty and the production cost are reduced.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

Detection method for drugs and personal care products in soil

PendingCN121476453AComponent separationTriclosanSolid phase extraction
The invention relates to the technical field of analysis and detection, in particular to a method for detecting drugs and personal care products in soil. According to the extraction, separation and enrichment steps of the traditional Chinese medicines and the personal care products, accelerated solvent extraction and solid-phase extraction are combined, so that the extraction rate of the various medicines and the personal care products in the soil can be remarkably increased, the sample loss rate is reduced, and the extraction time is shortened. According to the method, accelerated solvent extraction and solid-phase extraction are combined with a high-performance liquid chromatography coupling technique, isocratic elution is performed for 15-20 minutes, so that various trace drugs and personal care products with different structures and different polarities, such as ibuprofen, carbamazepine, bisphenol A and triclosan, which are remained in soil can be simply, quickly, accurately and universally detected, and the sensitivity is high. Moreover, the detection method provided by the invention is high in accuracy and good in reproducibility, and a rapid, accurate, visual, qualitative and quantitative determination method for the soil traditional Chinese medicines and the personal care products is provided for environmental detection departments, governments and enterprises.
Owner:SHANGHAI ACAD OF AGRI SCI

Iron-manganese modified recycled aggregate wetland filler and triclosan removal method

PendingCN122627586AConstructed wetlandTriclosan
The present application relates to the technical fields of environmental water treatment, artificial wetland filler preparation and building solid waste resource utilization, and discloses an iron-manganese modified recycled aggregate wetland filler and a triclosan removal method. The filler takes waste concrete recycled aggregate as a base body, is subjected to crushing, screening, washing and drying, and then is subjected to hydrochloric acid washing activation, sodium hydroxide alkali washing pore expansion and in-situ iron-manganese component deposition and loading in sequence, and then is dried and calcined, so that iron-manganese composite oxides are fixed on the outer surface of the aggregate and in the surface layer connected pores, and an iron-manganese active interface is formed. When water containing triclosan flows through the modified filler layer, triclosan enters the surface layer pores of the filler, and is enriched and fixed on the rough pore wall and the surface of the iron-manganese composite oxides, so as to reduce the triclosan concentration of the effluent. In the operation process of the method, no powder adsorbent or oxidant needs to be continuously added, the filler particle morphology is stable, and the method can be used for purification treatment of urban tail water, landscape water supplement and surface runoff affected by domestic source pollution.
Owner:NINGXIA UNIVERSITY