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57 results about "Triclosan" patented technology

Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.

Antibacterial polypeptide and application thereof in preparation of pet shower gel

The invention discloses antibacterial polypeptide and application thereof in preparation of pet shower gel, and belongs to the technical field of antibacterial polypeptide. The antibacterial polypeptide is prepared from the following raw materials in parts by weight: 2 to 5 parts of glycerol, 3 to 5 parts of plant polypeptide, 20 to 40 parts of sorbitol, 1 to 2 parts of sodium carboxymethyl cellulose, 0.5 to 1 part of xanthan gum, 2 to 5 parts of sodium methyl hydroxybenzoate, 0.5 to 1 part of a surfactant, 0.5 to 1 part of chlorhexidine, 0.05 to 0.3 part of triclosan and 100 parts of deionized water. The antibacterial polypeptide prepared by the invention can be applied to the preparation process of pet shower gel, and has good antibacterial performance.
Owner:SUKOTONG BIOTECHNOLOGY (TAIZHOU) CO LTD

Triclosan antibacterial coating surgical suture and preparation method thereof

The invention relates to the technical field of biomedicine, and discloses a triclosan antibacterial coating surgical suture and a preparation method thereof.The suture comprises a base material and a surface antibacterial coating, the base material is selected from one of an absorbable single-strand material, an absorbable multi-strand material, a non-absorbable single-strand material and a non-absorbable multi-strand material, and the surface antibacterial coating is selected from one of an absorbable multi-strand material and a non-absorbable multi-strand material; the antibacterial coating comprises triclosan, a high-molecular carrier and an auxiliary agent, the surface energy of a hydrophobic material is improved, the porosity of a hydrophilic material is increased, the adhesive force between the coating and different base materials is ensured, the base materials can be covered, the uniformity deviation of the coating is avoided, and the coating is free of cracking or falling off through the combination of plasma cleaning and roughening treatment on the surface of the base materials. A synergistic system is formed by triclosan, nano-silver and titanium dioxide, a dual mechanism of targeted destruction of bacterial cell membranes and free radical oxidation is achieved, the antibacterial rate is increased, the MRSA inhibition rate is increased, the degradation rate is regulated and controlled through the polylactic acid-glycolic acid copolymer carrier molecular weight and the lactic acid / glycolic acid proportion, and a curing dynamic formula is combined.
Owner:NANJING JUANRUN MEDICAL TECH CO LTD

Bacterial culture medium for producing algin through liquid fermentation

The invention discloses a bacterial culture medium for producing algin through liquid fermentation. The bacterial culture medium contains triclosan and SDS (Sodium Dodecyl Sulfate). Tests show that the PIB culture medium added with triclosan and SDS can improve the capability of producing algin by PFAC-PAO1 liquid fermentation. Accordingly, the inventor develops innovative research of optimizing the culture medium, the ChinaYin culture medium is finally obtained, and the specific formula of the ChinaYin culture medium is as follows: 20g / L of tryptone, 1.4 g / L of magnesium chloride, 10g / L of potassium sulfate, 20mL / L of glycerol, 50mu g / mL of triclosan and 125mu g / mL of SDS (Sodium Dodecyl Sulfate). Researches show that by applying the culture medium, the polysaccharide yield is higher than that of a PIB culture medium and a USAYu culture medium, the yield in 48 hours is higher than that of 24 hours and 72 hours, the yield of algin powder obtained in each culture bottle can reach 8 g / L, and it is indicated that the ChinaYin culture medium has the potential of being industrially amplified to be used for fermentation production of bacterial algin.
Owner:GUANGXI UNIV

Oral cavity antibacterial paste capable of deeply resisting bacteria and preparation method of oral cavity antibacterial paste

The invention relates to the field of oral cleaning products, in particular to oral antibacterial paste capable of deeply resisting bacteria and a preparation method of the oral antibacterial paste. According to the technical scheme, the incision smearing healing medicine capable of achieving rapid treatment is prepared from 15-25 parts of hydrated silica, 53-67 parts of sorbitol, 5.1-9.1 parts of water, 1.5-2.5 parts of cocamidopropyl betaine and 4-6 parts of glycerin, pathogenic bacteria are rapidly killed through triclosan, the micro-ecology is continuously adjusted through probiotics and plant extracts, the risk of drug resistance is reduced, and the healing effect is good. The plant anti-inflammatory components in the traditional Chinese medicine mixed extract are combined with the glycerol, so that red and swollen gums are relieved, wound healing is accelerated, then cocamidopropyl betaine is used for mildly cleaning oral mucosa, assisting in removing food residues and reducing bacterial attachment, and the anti-inflammatory effect is achieved. The toothpaste can deeply clean dead corners such as gingival gaps and deep mucous membranes, and can deeply play a role in the interior by virtue of an anti-bacteria and decomposition technology, so that the problem that a common oral product is limited in cleaning effect and only can clean the surface is solved.
Owner:JIANGSU HAOMIAO TRADITIONAL CHINESE MEDICINE RESEARCH CO LTD

Medical sterile ultrasonic coupling agent and preparation method thereof

The invention relates to the technical field of medical coupling agents, and discloses a medical sterile ultrasonic coupling agent which comprises the following components: carbomer, a humectant, a quaternary ammonium salt disinfectant, a preservative, a pH regulator and purified water. A preparation method of the medical sterile ultrasonic coupling agent comprises the following steps: step 1, dispersing the carbomer in part of purified water, stirring until the carbomer is completely swelled, adding the preservative and the pH regulator, and continuously stirring for 20 minutes; step 2, dissolving a quaternary ammonium salt disinfectant and a humectant in the residual purified water, uniformly mixing, adding into the gel in the step 1, and vacuumizing and stirring for 10 minutes; and step 3, performing irradiation sterilization after filling to obtain a finished product. Compared with the prior art, the invention has the advantages that: the quaternary ammonium salt is used for replacing triclosan, so that skin irritation and environmental pollution are avoided, and the safety is high. A solubilizer is not needed, and the production process is simplified. According to the invention, the compatibility problem of quaternary ammonium salt and carbomer is solved through a special process, and the stability and viscosity of the product are ensured.
Owner:SHANDONG JIUER IND GRP CO LTD

ELISA Kit for Detecting Triclosan Residue Based on Nanobody and Its Application

The present invention provides an ELISA kit for detecting triclosan residues based on nanobody and its application. The kit includes a box body, a detachable enzyme-labeled plate disposed in the box body, and reagents disposed in the box body; wherein, each well of the enzyme-labeled plate is coated with a triclosan artificial antigen, and the reagents include the nanobody shown in SEQ ID NO:1, as well as a triclosan standard solution, an enzyme-labeled secondary antibody, a PBS buffer solution, a PBST washing solution, a chromogenic solution, a reaction termination solution, etc. The kit of the present invention can accurately and sensitively detect triclosan residues in environments such as water, soil, and vegetables. The sample pretreatment process is simple and time-consuming less, and a large number of samples can be detected simultaneously. The sample detection cost is much lower than the traditional instrument detection method.
Owner:CHINA AGRI UNIV

Biomarkers for predicting the risk of prostate cancer caused by triclosan and applications thereof

PendingCN122326750ATriclosanProstate cancer
This invention relates to biomarkers and their applications for predicting the risk of prostate cancer induced by triclosan, belonging to the fields of environmental health and tumor biology. This invention systematically identifies oncogenes CHRM5, PLK1, ALB, and TOP2A associated with triclosan exposure and constructs a predictive model for the risk of prostate cancer induced by triclosan using machine learning methods. Therefore, this invention provides novel biomarkers and potential therapeutic targets for predicting the risk of prostate cancer induced by triclosan.
Owner:GUANGZHOU FIRST PEOPLES HOSPITAL (GUANGZHOU DIGESTIVE DISEASE CENT GUANGZHOU FIRST PEOPLES HOSPITAL GUANGZHOU MEDICAL UNIV THE SECOND AFFILIATED HOSPITAL OF SOUTH CHINA UNIV OF TECH)

sutures

The invention relates to a suture thread material comprising at least one polymer and at least one eutectic mixture. The polymer can be a biocompatible polymer such as polycaprolactone or PLGA. The eutectic mixture comprises triclosan. Other eutectic mixtures can be used in suture thread materials to reduce SSis and / or to decrease pain and / or to increase lubricity of sutures. The invention also provides a method for the production of sutures with drug loadings, the method comprising the use of therapeutic deep eutectic solvent (THEDES) technology to significantly increase drug content in suture matrices.
Owner:QUEENS UNIV OF BELFAST

A production method for multi-stage disinfection and aseptic packaging of medical cotton swabs

The present invention discloses a method for producing multi-stage disinfected and aseptically packaged medical cotton swabs. In the present invention, the antimicrobial agent is prepared through a sophisticated process to ensure uniform dispersion and stable bonding of nanosilver particles to the cotton swab material, maximizing the beneficial effects of the antimicrobial agent. This carefully designed formula provides sustained antimicrobial action. The large specific surface area of ​​the nanosilver particles ensures ample contact with microorganisms, rapidly killing or inhibiting their growth. The addition of triclosan and quaternary ammonium salts enhances the antimicrobial spectrum, making it effective against a variety of pathogens. During the preparation process, a sustained-release carrier effectively controls the release rate of the antimicrobial agent, ensuring that the antimicrobial agent continues to work over an extended period. The sustained-release carrier allows the antimicrobial agent to be slowly released from the surface or interior of the cotton swab, maintaining its antimicrobial effect over a longer period of time, reducing the need for frequent replacement of disinfectant products and enhancing the stability of the antimicrobial agent.
Owner:SICHUAN SUINING KANGDA HEALTH MATERIALS CO LTD

An upconversion composite nanomaterial for detecting triclosan, and its preparation method and application

The present invention discloses an upconversion composite nanomaterial for detecting triclosan, its preparation method and application, and belongs to the technical field of triclosan detection. The upconversion composite nanomaterial provided by the present invention comprises carbon dots, upconversion nanoparticles and ruthenium salt; the upconversion nanoparticles are core-shell structures, which are NaYF4:Yb 3+ / Er 3+ The nanoparticles are the core, and the surface of the core is coated with NaYF4:Eu 3+ The carbon dots and upconversion nanoparticles are connected via an amide bond. The upconversion composite nanomaterial provided by the present invention is low-cost, has a relatively simple preparation method, and exhibits high fluorescence emission intensity. It can be used to detect triclosan concentration in a simple, convenient, and low-cost manner, while enabling on-site detection and real-time monitoring.
Owner:DEZHOU UNIV

High-temperature-resistant functional food preservation bag and manufacturing method thereof

The invention relates to the technical field of food fresh-keeping bags, and discloses a high-temperature-resistant functional food fresh-keeping bag and a manufacturing method thereof.The food fresh-keeping bag is obtained by taking polyethylene as a base material and taking a high-temperature-resistant modifier, hydroxyapatite antibacterial filler and the like as auxiliary materials through mixing, extrusion, film blowing and bag manufacturing, the high-temperature-resistant modifier contains hydroxyl and a hindered phenol antioxidant structure, and acts with the compatilizer through melt blending, so that the high-temperature-resistant performance of polyethylene is improved, polypropylene is endowed with oxidation resistance, and the problem of oxygen aging is avoided; the hydroxyapatite antibacterial filler is prepared by grafting the triclosan on the hydroxyapatite, the dispersity of the hydroxyapatite is improved through grafting, the strength and toughness of the polyethylene can be effectively improved through uniform dispersion, and the triclosan has broad-spectrum antibacterial property and endows the polyethylene with antibacterial property.
Owner:DONGGUAN ZHENGLI PACKAGING MATERIALS CO LTD

A hydrolysis device for producing triclosan

ActiveCN224686891UBiotechnologyTriclosan
The utility model discloses a kind of hydrolysis devices for producing triclosan, including hydrolysis reactor, hydrolysis reactor;Hydrolysis reactor is equipped with stirring mechanism, and stirring mechanism includes stirring shaft, spiral stirring vane, stirring motor interface, spiral stirring vane is also equipped with multiple non-parallel setting auxiliary stirring vane, spiral stirring vane and auxiliary stirring vane are equipped with turbulence hole;The bottom of stirring shaft is equipped with buffer cavity, and buffer cavity is communicated with the hollow stirring rod of being arranged in the lower portion of stirring shaft, and the main gas outlet hole is equipped on the hollow stirring rod;The bottom of stirring shaft is communicated gas pipeline by swivel joint;The inner wall of hydrolysis reactor is equipped with annular array ultrasonic transducer.This device guarantees that hydrolysis reaction is carried out fully, avoids the occurrence of side reaction, improves the production efficiency of product, and tail gas produced in hydrolysis process is fully treated, avoids its pollution to environment.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

A method for treating a triclosan antibacterial coating on sutures

The present application relates to the technical field of antibacterial coating, in particular to a processing method of triclosan antibacterial coating for suture, and the specific steps are as follows: S1, preparation of moxa tablet-triclosan antibacterial solution; S2, preparation of moxa tablet-triclosan spraying solution; S3, suture pretreatment; S4, suture spraying.The present application has the following beneficial effects: 1. Good versatility: the suture with moxa tablet-triclosan antibacterial coating prepared by the present application is sprayed by ultrasonic spraying machine, and the same production process is used for different suture materials and single or multi-strand sutures, so that the production cost is greatly reduced, and the development of enterprises is facilitated; 2. Broad-spectrum bacteriostasis: the suture has good bacteriostatic rate for staphylococcus aureus, escherichia coli and stenotrophomonas maltophilia; 3. Low allergenicity.
Owner:NANJING JUANRUN MEDICAL TECH CO LTD

A functional fiber membrane for bacterial visual monitoring and response antibacterial and its preparation method and use

ActiveCN118087155BTriclosanFiber
The application provides a functional fiber membrane for bacterial visual monitoring and response antibacterial and a preparation method and application thereof, and belongs to the field of biological medical materials. The functional fiber membrane is a fiber membrane with a double-layer structure. A lower membrane of the fiber membrane is prepared from TCS@ZIF-8 nanoparticles and poly-epsilon-caprolactone as raw materials. An upper membrane of the fiber membrane is prepared from poly-epsilon-caprolactone, polyethylene glycol and bromo-musk toluene phenol blue as raw materials. The TCS@ZIF-8 nanoparticles are prepared from the following raw materials in a weight ratio: zinc nitrate hexahydrate 1-5 parts, triclosan 1-5 parts and 2-methyl imidazole 1-5 parts. The functional fiber membrane can realize naked-eye monitoring of various bacteria in a short time, has high monitoring sensitivity and can meet the clinical diagnosis requirements. Meanwhile, the membrane has excellent antibacterial performance and can synergistically antibacterial with photocatalysis. The functional fiber membrane has a simple preparation process, is convenient to operate and is convenient to carry, provides a feasible scheme for bacterial monitoring and has application prospects.
Owner:SICHUAN UNIV +3

Preparation process of deodorization electrostatic spinning solution and method for producing deodorization yarn

The invention discloses a preparation process of a deodorizing electrostatic spinning solution, which comprises the following steps: step 1, weighing TPU (thermoplastic polyurethane), dissolving the TPU in N, N-dimethylformamide, and controlling the mass fraction of the TPU in the solution to be 5-15%; and 2, weighing 2-4% of triclosan, 0.5-2% of nano zinc oxide, 1-4% of tea polyphenol and 1-4% of beta-cyclic refined paste based on the total mass of the solution, mechanically stirring for 24 hours, and dispersing in the solution to prepare the deodorizing electrostatic spinning solution. According to the invention, the deodorizing functional auxiliary agent is compounded into the spinning substrate by utilizing an electrostatic spinning technology, and the deodorizing functional fiber is wrapped in the middle of the card sliver, so that a finished fabric made of the yarn has a high deodorizing effect.
Owner:JIANGSU YDTEX GRP LTD

A ratiometric fluorescent probe for detecting triclosan based on metal-organic framework materials and its preparation and application

The present invention relates to a ratiometric fluorescent probe for detecting triclosan based on a metal-organic framework material, and its preparation and application. The fluorescent probe is prepared by the following method: UiO-67-bpy powder is first reacted with EuCl3 to generate Eu@UiO-67-bpy, which is then reacted with CDs to obtain a pale yellow Eu / CDs@UiO-67-bpy solid powder, which is the target product. Compared with the prior art, the fluorescent probe of the present invention can detect triclosan with ultrafast response speed, excellent selectivity, good anti-interference ability, high sensitivity, no interference from environmental factors, and higher accuracy without the need for tedious pretreatment and professional operation, and can still have excellent selectivity for triclosan in the presence of other organic substances with similar structures to triclosan.
Owner:SHANGHAI NORMAL UNIVERSITY

Antimicrobial cyanoacrylate formulations

Described herein are polymerizable compositions useful as surgical adhesives, where the compositions include at least one antimicrobial agent dissolved in a cyanoacrylate monomer, where the at least one antimicrobial agent includes a cinnamon derivative comprising at least one of cinnamaldehyde, a cinnamic ester, a cinnamon essential oil, and where the at least one antimicrobial agent optionally further includes triclosan or a derivative thereof and / or povidone iodine. The antimicrobial agent is soluble in and compatible with the cyanoacrylate monomer.
Owner:CHEMENCE MEDICAL

High-strength corrosion-resistant inflatable boat material and preparation method thereof

The invention discloses a high-strength corrosion-resistant inflatable boat material and a preparation method thereof, and relates to the technical field of inflatable boat material processing. The method comprises the following steps: preparing 90-100 parts of TPU particles, 20-30 parts of aramid fibers, 15-20 parts of polyester fibers, 5-8 parts of nano silicon dioxide, 10-15 parts of an epoxy resin modifier, 2-3 parts of an anti-ultraviolet agent, 3-5 parts of nano zirconium phosphate, 8-10 parts of a flame retardant, 1-2 parts of a silane coupling agent, 0.5-1 part of an antioxidant and 8-13 parts of an antibacterial intermediate; wherein the antibacterial intermediate is prepared by the following steps: step 1, adding triclosan, nano silicon dioxide and polyethylene wax into a mixing machine; the antibacterial intermediate is added into the raw materials, the nano silicon dioxide is subjected to silanization treatment, and the synergistic effect of the antibacterial intermediate and the silanized nano silicon dioxide is utilized, so that double optimization of the surface performance and the internal structure of the material is realized.
Owner:JIANGSU NEW RAINBOW MSTAR TECH LTD

Application of compound triclosan in preparation of medicine for treating toxoplasmosis

The invention discloses application of a compound triclosan in preparation of a medicine for treating toxoplasmosis. The medicine is used for inhibiting toxoplasmosis proliferation. The medicine is used for relieving pathological injuries of one or more organs caused by toxoplasma gondii infection, and the organs comprise the heart, the liver, the spleen, the kidney and the brain. The medicine is used for protecting brain tissues or penetrating a blood brain barrier to treat toxoplasma gondii infection of a central nervous system; the medicine comprises a therapeutically effective amount of triclosan and a pharmaceutically acceptable carrier or auxiliary material, the dosage form of the medicine is an oral preparation; the application has the beneficial effects that the broad-spectrum antibacterial agent triclosan is proved to have a new application of remarkably treating toxoplasmosis for the first time, in-vivo and in-vitro experiments prove that triclosan can effectively inhibit the proliferation of toxoplasmosis, the effect is dose-dependent, and in an acute infection mouse model, triclosan can remarkably improve the survival rate of mice and reduce the ascites insect-bearing quantity, so that the effect of treating toxoplasmosis is achieved. The pathological injury of multiple organs such as heart, liver, spleen and kidney can be relieved.
Owner:LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS +1

A compound traditional Chinese medicine detoxification ointment and a preparation method thereof

This invention discloses a compound traditional Chinese medicine detoxifying ointment and its preparation method. The compound traditional Chinese medicine detoxifying ointment comprises a traditional Chinese medicine extract, triclosan, a gel matrix, a cooling and antipruritic agent, a moisturizer, a surfactant, a pH adjuster, and purified water. The traditional Chinese medicine extract is prepared by a group extraction process using five medicinal slices—honeysuckle, scutellaria, coptis, rhubarb, and corydalis—in a specific ratio: honeysuckle, scutellaria, and corydalis form the first group, while coptis and rhubarb form the second group. These are extracted separately by ethanol reflux extraction and microfiltration purification, then a colloidal dispersion system is formed using a pH segmented control method, followed by concentrating the extracts. This invention, through the synergistic combination of the traditional Chinese medicine extract, low-concentration triclosan, and the cooling and antipruritic agent, enables the product to possess multiple effects, including highly effective broad-spectrum antibacterial properties, cooling and antipruritic effects, and blood-activating and analgesic effects. Furthermore, it is non-irritating to the skin, exhibits good stability, and is suitable for industrial production.
Owner:HANGZHOU CHILDRENS HOSPITAL +1

Self-adaptive phase-change microstructure antibacterial antifouling coating as well as preparation method and application thereof

The invention discloses a self-adaptive phase-change microstructure antibacterial antifouling coating as well as a preparation method and application thereof. The method comprises the following steps: (1) synthesizing a bacteriostatic active silane functional element; (2) synthesizing a phase change type active silane functional element; (3) synthesizing antibacterial organic silicon resin with a phase change function; and (4) preparing the composite array microstructure antibacterial antifouling coating. The preparation method comprises the following steps: firstly constructing a triclosan and / or coumarin-based synergistic antibacterial element, then preparing a long-chain alkyl phase-change functional element, then preparing organic silicon resin through polycondensation, and finally compounding the organic silicon resin with a nano filler, and molding to obtain the array microstructure coating. Under high temperature or strong light, the modulus of the microstructure coating is reduced, large-amplitude swing is generated, and contamination attachment is inhibited; in a low-temperature or dark environment, the modulus is increased, the microstructure is stable, and the durability is improved. A phase change driven modulus regulation and control mechanism is coupled with antibacterial elements, microstructures and low surface energy characteristics of organic silicon, so that self-adaptive antifouling in a complex environment is realized.
Owner:QUZHOU RES INST OF ZHEJIANG UNIV

Method for producing amino water reducer by using triclosan etherification wastewater extract

The invention relates to the technical field of industrial wastewater, in particular to a method for producing an amino water reducing agent by using triclosan etherification wastewater extract, which comprises the following steps: (1) taking collected triclosan etherification wastewater, adjusting the pH value to be acidic, layering, and collecting upper-layer extract and lower-layer wastewater; (2) taking lower-layer wastewater, adding an extracting agent, stirring, and concentrating and crystallizing the collected lower-layer potassium chloride solution to obtain a potassium chloride product; an upper-layer extract and condensate water are reserved for use; and (3) taking condensate water, adding phenol, sodium sulfanilate, the upper-layer extract and the upper-layer extract, stirring, adjusting the pH value to be alkaline, heating, dropwise adding formaldehyde, continuously heating for reaction, cooling, adjusting the pH value, and adding water to adjust the solid content, thereby obtaining the amino water reducer. According to the method, zero discharge of the triclosan etherification waste liquid is realized, the current pollution situation of the phenol-containing waste water is effectively improved, the environment is protected, the triclosan etherification waste water is comprehensively utilized, and the method has good economic benefits and environmental protection benefits.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

Bacteriostatic nursing gel with immunity enhancing effect and preparation method thereof

The invention discloses antibacterial nursing gel with an immunity enhancing effect and a preparation method thereof. Comprising the following raw materials in parts by weight: 0.5 to 3 parts of carbomer, 0.5 to 3 parts of triethanolamine, 80 to 94 parts of purified water, 0.1 to 1 part of chitosan, 0.01 to 0.1 part of triclosan, 0.1 to 0.3 part of phenoxyethanol, 0.5 to 5 parts of a radix stemonae extract, 0.01 to 0.5 part of a saffron crocus extract, 0.5 to 3 parts of a cortex phellodendri extract, 0.5 to 3 parts of a fructus cnidii extract and 0.5 to 3 parts of a radix sophorae flavescentis extract. The prepared gel product is suitable for treating or preventing skin and mucous membrane infection, inflammation and related symptoms, meanwhile, the immune function can be adjusted, the body resistance is improved, and comprehensive protection is provided for female health.
Owner:GUANGZHOU SAIMEI PHARM CO LTD

A device for preparing triclosan

The utility model discloses a triclosan preparation device relates to triclosan production technical field, including first reactor, the inlet of first reactor is respectively through pipeline intercommunication with 2,4 - dichlorophenol jar, sodium hydroxide solution jar, xylene jar I and tetrabutyl ammonium bromide jar, the outlet of first reactor is through pipeline intercommunication with second reactor, the inlet of second reactor is respectively through pipeline intercommunication with 2 - chloro - 5 - nitrobenzene methyl ether jar, dilute hydrochloric acid solution jar, ZnCl2 - Al2O3 solid acid jar, nano TiO2 jar and xylene jar II, the outlet of second reactor is through pipeline intercommunication with third reactor, the inlet of third reactor is through pipeline intercommunication with acetic acid jar, the top gas phase export of third reactor is through pipeline intercommunication with first condenser, and the outlet of first condenser is through pipeline intercommunication with crude product jar, improves the yield of product.
Owner:SHANDONG AOYOU BIOLOGICAL TECH CO LTD

Formulation

ActiveUS12599555B2Organic active ingredientsAerosol deliveryTriclosanNedocromil Sodium
A composition, for example an oil-in-water emulsion, comprising an amphoteric surfactant, alkoxylated cetyl alcohol, a polar dmg and a preservative, wherein the total amount of preservative present in the composition is about 0.2% w / w or less and is not benzyl alcohol and / or triclosan. The drug may be sodium cromoglicate and / or nedocromil sodium. The formulation may be useful in the treatment of skin diseases such as atopic dermatitis.
Owner:HEWLETT HEALTHCARE LTD

Dental implant, surface treatment method thereof and composite material for dental implant

The invention relates to the technical field of dental implants, in particular to a dental implant, a surface treatment method of the dental implant and a composite material for the dental implant. The surface treatment method of the dental implant comprises the following steps: uniformly mixing zirconium oxide, tricalcium phosphate, monocalcium phosphate, tricalcium silicate, calcium hydroxide, triclosan and polyethylene glycol according to a preset proportion to obtain an initial mixture; grinding the initial mixed material to obtain a composite material; carrying out sand blasting-acid etching treatment on the cleaned and pretreated dental implant, and cleaning and drying; and coating the surface of the cleaned and dried dental implant with the composite material to finish surface treatment. According to the treatment method, the antibacterial property and hydrophilicity of the dental implant can be improved.
Owner:CHANGZHOU SIFARY MEDICAL TECH CO LTD

Skin antibacterial gel and preparation method thereof

The invention relates to the technical field of external medicine preparations, discloses skin antibacterial gel and a preparation method thereof, and aims to solve the technical problems that in the prior art, extraction of multi-polar active ingredients of Mongolian medicine is insufficient, and when natural extracts and chemical bacteriostatic agents are compounded, uneven dispersion, high irritation and poor stability are prone to occurring. The skin antibacterial gel is composed of Mongolian medicine extract, polyvinyl alcohol, xanthan gum, triclosan, glycerin, nicotinamide and other auxiliary materials. The preparation method is characterized in that the Mongolian medicine is extracted by adopting a gradient process combining ultrasonic water extraction and microwave alcohol extraction, so that active ingredients with different polarities are fully reserved; the triclosan is subjected to composite microencapsulation treatment through a trehalose and sodium hyaluronate compounded wall material; according to the preparation method, polyvinyl alcohol and xanthan gum are used for constructing an interpenetrating network matrix, laurocapram is introduced for optimizing the transdermal performance, the Mongolian medicine ingredient extraction efficiency is improved, and the obtained gel is reliable in antibacterial effect, stable in long-term storage performance, low in skin irritation and capable of meeting the skin antibacterial nursing requirement.
Owner:ORDOS MONGOLIAN MEDICINE HOSPITAL (ORDOS MONGOLIAN MEDICINE RES INST)

Formula and preparation method of marine organism preventing grease block and marine organism preventing effect monitoring method

The invention discloses a marine organism preventing grease block formula, a preparation method and a marine organism preventing effect monitoring method.The marine organism preventing grease block formula is prepared by adding aloe-emodin, potassium permanganate, triclosan, methylchavicol, calcium hypochlorite, water glass, geraniol and sodium stearate into a mixed solution composed of water and vegetable oil according to the proportion, conducting stirring, conducting filtering, collecting solids, and conducting drying to obtain the marine organism preventing grease block. The solid is dried and formed, the grease block is obtained, and the prepared grease block can effectively resist attachment of marine organisms in complex structure areas of marine facilities. When the marine organism prevention grease block is applied to marine organism adhesion prevention, the marine steel structure complex node marine organism prevention device is adopted, the cage type net is adopted for fixing the grease block, the concentration is increased, durability and stability are improved, the grease block is replaced every three months, and the consumption of the grease block is continuously supplemented; the monitoring device can monitor the marine organism prevention effect of a complex steel structure area in real time, and traditional methods such as video observation, underwater observation and weighing in the past are avoided.
Owner:CNOOC INFORMATION TECHNOLOGY CO LTD

Cr-MOF coated triclosan long-acting antibacterial mildew-proof leather finishing agent prepared based on tannery wastewater and method thereof

The invention discloses a Cr-MOF coated triclosan long-acting antibacterial mildew-proof leather finishing agent prepared based on tannery wastewater and a method thereof, the tannery wastewater is treated to obtain a CrCl3 solution, a terephthalic acid solution is added into the CrCl3 solution, the mixture is transferred into a high-pressure reaction kettle for reaction, the obtained product is centrifuged, washed and dried to obtain Cr-MOF particles, and the Cr-MOF particles are dried to obtain the Cr-MOF coated triclosan long-acting antibacterial mildew-proof leather finishing agent. The preparation method comprises the following steps: adding triclosan into a Cr-MOF dispersion liquid, stirring, centrifuging, washing and drying to obtain triclosan Cr-MOF nanoparticles, and blending the triclosan Cr-MOF nanoparticles with a polyurethane emulsion to obtain the antibacterial and mildew-proof composite leather finishing agent. According to the polyurethane-based triclosan Cr-MOF long-acting antibacterial mildew-proof leather finishing agent prepared on the basis of the tannery wastewater, resource utilization of the tannery wastewater is achieved, the prepared leather finishing agent with the long-acting antibacterial mildew-proof performance can prevent leather from being invaded by bacteria and molds, the quality of leather products is improved, and the service life of the leather products is prolonged.
Owner:SHAANXI UNIV OF SCI & TECH

Cashmere scarf with antibacterial property and preparation method thereof

The invention relates to the technical field of wool scarves, and discloses an antibacterial cashmere scarf and a preparation method thereof.The preparation method includes the following steps of pretreatment of high-quality cashmere, blending of antibacterial fibers, spinning, weaving, antibacterial after-treatment and finished product detection.The surface of the scarf is provided with antibacterial-treated real silk embroidery decorative threads; silver zeolite antibacterial agents are loaded on the real silk threads through an impregnation method, the edge of the scarf is of a special edge covering structure and comprises a built-in antibacterial fiber woven belt and a medical grade antibacterial silica gel edge sealing strip, and the silica gel edge sealing strip contains 3%-5% of triclosan antibacterial agents. Through a dual protection mechanism of fiber embedded antibacterial and surface antibacterial finishing, the problem that a single antibacterial mode is easy to lose efficacy is solved, a synergistic antibacterial effect is generated through compounding of nano-silver and chitosan, and then an antibacterial agent and fibers are firmly combined through a special after-finishing process, so that the antibacterial effect is good. Therefore, the long-acting antibacterial and washing-resistant effects are achieved through multiple antibacterial synergistic effects.
Owner:JIANGSU XINKAISHENG ENTERPRISE DEV