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567 results about "Triclosan" patented technology

Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including toothpaste, soaps, detergents, toys, and surgical cleaning treatments. It is similar in its uses and mechanism of action to triclocarban. Its efficacy as an antimicrobial agent, the risk of antimicrobial resistance, and its possible role in disrupted hormonal development remains controversial. Additional research seeks to understand its potential effects on organisms and environmental health.

Triclosan-containing medical devices

PCT No. PCT / US96 / 20932 Sec. 371 Date Jun. 30, 1998 Sec. 102(e) Date Jun. 30, 1998 PCT Filed Dec. 23, 1996 PCT Pub. No. WO97 / 25085 PCT Pub. Date Jul. 17, 1997The present invention relates to polymeric medical articles comprising the antiinfective agents chlorhexidine and triclosan. It is based, at least in part, on the discovery that the synergistic relationship between these compounds permits the use of relatively low levels of both agents, and on the discovery that effective antimicrobial activity may be achieved when these compounds are comprised in either hydrophilic or hydrophobic polymers. It is also based on the discovery that chlorhexidine free base and triclosan, used together, are incorporated into polymeric medical articles more efficiently. Medical articles prepared according to the invention offer the advantage of preventing or inhibiting infection while avoiding undesirably high release of antiinfective agent, for example into the bloodstream of a subject.
Owner:COLUMBIA UNIV OF THE CITY OF NEW YORK TRUSTEES OF THE

Triclosan and silver compound containing medical devices

The present invention relates to polymeric medical articles comprising combinations of triclosan and silver-containing compounds. It is based, at least in part, on the discovery that these agents act synergistically, thereby permitting the use of relatively low levels of both agents. While it had been previously found that triclosan can be particularly useful when used in conjunction with chlorhexidine, it has been further discovered that medical articles having suitable antimicrobial properties may be prepared, according to the present invention, which contain triclosan without chlorhexidine. Such medical articles offer the advantage of preventing or inhibiting infection while avoiding undesirable adverse reactions to chlorhexidine by individuals that may have sensitivity to chlorhexidine.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Triclosan-containing medical devices

The present invention relates to polymeric medical articles comprising the antiinfective agents chlorhexidine and triclosan. It is based, at least in part, on the discovery that the synergistic relationship between these compounds permits the use of relatively low levels of both agents, and on the discovery that effective antimicrobial activity may be achieved when these compounds are comprised in either hydrophilic or hydrophobic polymers.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Methods and kits for locking and disinfecting implanted catheters

InactiveUS6685694B2Reduce riskInhibiting fouling and plugging of the lumenDialysis systemsMedical devicesTriclosanThrombus
Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, in a range from 1% to 99% by volume, and an additive in a range from 1% to 99% by volume, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. The use of an alcohol and additive solution can effectively reduce fouling of the catheter, particularly clotting and thrombus in intravascular catheters, as well as eradicate existing infections and / or reduce the risk of potential infections. Existing infections and / or potential infections can be further reduced by employing a catheter body which permits an anti-microbial solution to penetrate into the catheter body and preferably through the catheter into tissue surrounding the implanted catheter.
Owner:EXCELSIOR MEDICAL

Toothpaste comprising bioadhesive submicron emulsion for improved delivery of antibacterial and anticaries agents

Toothpaste incorporating chlorhexidine bigluconate for improved adhesive onto the surface of the teeth. A second embodiment discusses the use of triclosan and in combination with sodium monofluorphosphate for use in the toothpaste.
Owner:ALPHARX

Germ-resistant communication and data transfer/entry products

InactiveUS6358519B1Decreased microbial capacityAvoid multiplicationCordless telephonesBiocideTriclosanGram
Articles and a method related to use of a biocide (e.g., triclosan) incorporated into communication and data transfer / entry products in order to provide cleaner, fresher and more hygienic surfaces by controlling a broad range of gram-positive and gram-negative bacteria, yeast, and fungi on the surfaces of such products.
Owner:CLEAN COMM

Antimicrobial and sporicidal composition

Germicidal compositions with enhanced activity towards killing microbiological spores and vetgetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric alcohols, hydrogen peroxide, iodine, triclocarban, triclosan or combinations thereof with one or more spore coat opening agents. The invention also provides for the application of the germicidal compositions to animate and inanimate surfaces to help kill germs and protect against the risk of infection from bacteria, molds, yeasts, fungi, viruses, and microbiological spores.
Owner:PURE IP LC

Chlorhexidine acetate antiseptic cleaning agent

ActiveUS7704935B1Efficient growth processKilling or preventing/impeding pathogen growthBiocideCosmetic preparationsTriclosanPolyester
An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and / or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.
Owner:BECTON DICKINSON & CO

Anti-tack spandex fibers containing antimicrobial agents therein and fabrics made therefrom

Polyurethane elastomer yams (particularly spandex) containing certain silver-based antimicrobial formulations therein are provided. This invention relates to polyurethane elastomer yams (particularly spandex) containing certain silver-based antimicrobial formulations therein. Such formulations comprise antimicrobial compounds, such as, preferably, triclosan and / or silver-containing ion-exchange resins, such as zirconium phosphate, glass, and / or zeolite compounds. The inventive spandex yarns exhibit excellent antimicrobial qualities as well as surprisingly good anti-tack / frictional characteristics. As a result, antimicrobial spandex yams are provided which exhibit ease in processing, particularly in further knitting, weaving, etc., to produce fabrics therefrom. Such fabrics are also encompassed within this invention.
Owner:MILLIKEN & CO

Combinations of antiseptic and antibiotic agents that inhibit the development of resistant microorganisms

The present invention relates to compositions comprising a combination of one or more antiseptic and an antibiotic. It is based, at least in part, on the discovery that such combinations tend to deter the formation of antibiotic-resistant organisms. In preferred, nonlimiting embodiments of the invention, the antibiotic is minocycline and the antiseptic is a chlorhexidine compound, triclosan, or benzalkonium chloride, and in particular embodiments, a silver salt or a bismuth salt is added. Examples of specific, nonlimiting embodiments of the invention include combinations of (i) minocycline, triclosan, and a bismuth salt; (ii) minocycline, a chlorhexidine compound, and a bismuth salt; and (iii) minocycline, benzalkonium chloride, and a bismuth salt. The present invention further provides for articles, such as, but not limited to, medical articles, which have been treated with or which otherwise comprise a combination of antiseptic and antibiotic.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Antimicrobial compositions containing cationic active ingredients and quaternary sugar derived surfactants

The antimicrobial composition of the present invention comprises a cationic active ingredient, a quaternized sugar-derived surfactant, and an optional foam boosting surfactant. The present antimicrobial compositions are free of the antimicrobial agent triclosan (i.e., 2,4,4′-trichloro-2′hydroxy-diphenylether), have a high cidal activity in a short amount of time, provide stable copious foam and exhibit enhanced tissue (e.g. skin) compatibility as defined by an in vitro whole toxicology assessment method.
Owner:ECOLAB USA INC

Wood preservative formulations comprising Imazalil

InactiveUS20060276468A1Synergistic effect preservationBiocideDead animal preservationTriclosanMedicine
The invention provides a wood preservative composition comprising a synergistic combination of imazalil or imazalil sulfate and one or more co-biocides. Examples of such co-biocides include triclosan, fenarimol, dichlorophen and chlorothalonil. The efficacy of potential wood preservative compositions can be tested by a simple test provided herein.
Owner:OSMOSE

A kind of toothpaste containing Panax notoginseng and propolis and its preparation method

The invention relates to toothpaste including radix notoginseng and propolis and a preparation method thereof. The toothpaste comprises the following raw materials according to percentage by weight: 0.1-1.5% of radix notoginseng extract, 0.03-3.2% of propolis powder, 25-46% of natural calcium carbonate, 5-15% of silica, 3-20% of glycerol, -4001-10% of polyethylene glycol, 0.2-1.0% of sodium pyrophosphate, 0.2-1.5% of xanthan gum, 0.1-1.5% of carboxymethyl cellulose, 3-25% of sorbic alcohol, 0.1-1% of saccharin sodium salt, 1-5% of lauryl sodium sulphate, 0.05-0.5% of sodium ethyl p-hydroxybenzoate, 0.02-2% of sodium propylparaben, 0.3-3% of essence, 0.01-0.3% of triclosan, 0.05-2% of zinc citrate, and the balance of water. The natural nursing toothpaste including the radix notoginseng extract has obvious curative effects on gingivitis, bleeding gums, dental ulcer and the like. The propolis has the functions of diminishing inflammation, easing pain and stopping bleeding. The radix notoginseng and the propolis are used in the toothpaste at the same time so that the toothpaste has more obvious effects for stopping pain and resisting gingivitis, bleeding gums and pain.
Owner:YUNNAN PHYTOPHARML

Cyanoacrylate compositions containing anti-microbial agent

A monomeric adhesive composition includes a polymerizable monomer, such as a 1,1-disubstituted monomer such as a cyanoacrylate, and an antimicrobial agent, wherein the antimicrobial agent is a phenolic active compound. Examples of suitable phenolic active compounds include halogenated phenol compounds such as chlorinated phenol compounds (such as triclosan) and brominated phenol compounds.
Owner:ETHICON INC

Cyclodextrins in dental products

Oral rinse and dentifrice compositions, comprising a phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl β-cyclodextrin, hydroxyethyl β-cyclodextrin, hydroxypropyl γ-cyclodextrin, hydroxyethyl γ-cyclodextrin, α-cyclodextrin, methyl β-cyclodextrin, and mixtures thereof. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.
Owner:MCNEIL PPC INC

Whole Mouth Malador Control By A Combination Of Antibacterial And Deodorizing Agents

Disclosed are oral care compositions effective to control mouth and breath malodour comprising in a pharmaceutically acceptable carrier, a combination of an antibacterial agent and a deodorizing or odor-neutralizing agent comprising a compound having the structurewherein R1, R2, R3, and R5 may be identical or different, each representing H, a linear or branched C1-C6 alkyl or alkenyl, phenyl, —OH or —ORa; R4 is —OH, —ORa, phenyl, or a linear or branched C1-C6 alkyl or alkenyl; and Ra is phenyl or a linear or branched C1-C6 alkyl or alkenyl. The odor-neutralizing agent may further comprise one or more of an additional odor-neutralizing compound selected from α-damascenone, α-isomethylionone, α-ionone, β-ionone, pulegone, piperitone, carvone, coenzyme Q10 or cinnamaldehyde.The antibacterial agent may comprise one or a mixture of a quaternary ammonium compound selected from cetylpyridinium chloride, tetradecylpyridinium chloride, N-tetradecyl-4-ethyl pyridinium chloride or domiphen bromide; metal ions such as stannous, zinc or copper; chlorhexidine; triclosan; triclosan monophosphate; or selected essential oils.
Owner:THE PROCTER & GAMBLE COMPANY

Methods and kits for locking and disinfecting implanted catheters

InactiveUS20020010438A1Reduce riskInhibiting fouling and plugging of the lumenDialysis systemsMedical devicesTriclosanThrombus
Implanted catheters are locked with a solution comprising a lower alcohol, typically ethanol, propanol, or butanol, in a range from 1% to 99% by volume, and an additive in a range from 1% to 99% by volume, the additive comprising an anti-microbial, typically taurolidine or triclosan, or an anti-coagulant, typically riboflavin, sodium citrate, ethylene diamine tetraacetic acid, or citric acid. The use of an alcohol and additive solution can effectively reduce fouling of the catheter, particularly clotting and thrombus in intravascular catheters, as well as eradicate existing infections and / or reduce the risk of potential infections. Existing infections and / or potential infections can be further reduced by employing a catheter body which permits an anti-microbial solution to penetrate into the catheter body and preferably through the catheter into tissue surrounding the implanted catheter.
Owner:EXCELSIOR MEDICAL

Combinations of antiseptic and antibiotic agents containing medical devices

The present invention relates to compositions comprising a combination of one or more antiseptic and an antibiotic. It is based, at least in part, on the discovery that such combinations tend to deter the formation of antibiotic-resistant organisms. In preferred, nonlimiting embodiments of the invention, the antibiotic is minocycline and the antiseptic is a chlorhexidine compound, triclosan, or benzalkonium chloride, and in particular embodiments, a silver salt or a bismuth salt is added. Examples of specific, nonlimiting embodiments of the invention include combinations of (i) minocycline, triclosan, and a bismuth salt; (ii) minocycline, a chlorhexidine compound, and a bismuth salt; and (iii) minocycline, benzalkonium chloride, and a bismuth salt. The present invention further provides for articles, such as, but not limited to, medical articles, which have been treated with or which otherwise comprise a combination of antiseptic and antibiotic.
Owner:MODAK SHANTA M +2

Method of decreasing sebum production

InactiveUS20050053631A1Decreasing sebum synthesisReducing sebum synthesisOrganic active ingredientsCosmetic preparationsTriclosanΑ methylene γ butyrolactone
Cosmetic compositions and methods of decreasing sebum production by contacting sebocytes with a fatty acid synthase inhibitor, including cerulenin, triclosan, α-methylene-γ-butyrolactone, and EGCG, as well as mixtures thereof and analogs thereof. The invention further relates to a cosmetic method of identifying sebum production inhibiting actives comprising contacting the active with FAS and detecting a reduction in sebum amount production in sebocytes.
Owner:UNILEVER HOME & PERSONAL CARE USA DIV OF CONOPCO IN C

Medical devices having antimicrobial properties

Microbial growth on the surface of a valve of a voice prosthesis and optionally the cartridge or ring supporting the valve, is inhibited by providing antimicrobial activity at a level sufficient to retard growth of a microbial film by dispersing an inorganic antimicrobial agent such as silver oxide or an organic antimicrobial agent such as triclosan or butyl paraben dispersed in a medical grade silicone elastomer. The valve, ring or cartridge is in contact with body fluids containing microorganisms and nutrients therefor. The antimicrobial surface can interfere with or inhibit the growth of a biofilm, bacterial layer or a yeast layer. The body of the prosthesis may also contain an antimicrobial surface as long as it is non-toxic to the tissue it contacts.
Owner:FREUDENBERG MEDICAL

Antimicrobial isopropyl alcohol and organofunctional silane solution

A surface of an object may be treated using an antimicrobial wipe presoaked in an antimicrobial treatment solution. Alternatively, the antimicrobial treatment solution may be sprayed directly on the surface. The antimicrobial treatment solution may be made of isopropyl alcohol and an unreacted organofunctional silane antimicrobial substance that is substantially free from arsenic, silver, tin, heavy metals and polychlorinated phenols. The antimicrobial substance may include any one of: 3 trimethoxysilylpropyloctadecyldimethyl ammonium chloride; hyaluronan and its derivatives; triclosan; and a copolymer of chloropropyltrihydroxysilane and octadecylaminodimethyltrihydroxysilylpropyl ammonium chloride.
Owner:PARASOL MEDICAL

Citrus scion pretreatment technology for promoting removal of composite infection pathogens

The invention discloses a citrus scion pretreatment technology for promoting removal of composite infection pathogens. The citrus scion pretreatment technology includes acquiring citrus branches, pruning the citrus branches to remove leaves and leaf stalks and disinfecting the surfaces of the citrus branches by the aid of sodium hypochlorite (NaClO) aqueous solution; detecting molecules of scions of the citrus branches with the disinfected surfaces; performing detoxification treatment on scion materials by the aid of insecticides if the detected citrus branches are infected by HLB (huanglongbing) viruses and CTV (citrus tristeza viruses), acquiring virus-free shoots and completing the citrus scion pretreatment detoxification step. The citrus scion pretreatment technology has the advantages that the citrus branches are treated by the aid of small-molecule bactericide triclosan (TCL) and a plurality of antibiotics, so that virus-free stem tip materials without the citrus tristeza viruses (CTV) and huanglongbing (HLB) pathogens can be acquired; the detoxification efficiency is high, and a good effect can be realized; the virus-free stem tip materials can be provided for further stem tip micro-shoot grafting or tender-shoot grafting.
Owner:HUAZHONG AGRI UNIV

Flavoured mouth wash composition

The present invention provides a flavoured product comprising four or more flavour materials having antimicrobial properties and selected from the group comprising nonanol, decanol, nonanal, decanal, amyl propionate, anethole synthetic, anisic aldehyde, basil oil, benzyl benzoate, benzyl butyrate, benzyl formate, camomile oil, cinnamic aldehyde, cis-3-hexenol, clove bud oil, damascone, ethyl acetoacetate, eucalyptus oil, ginger, isoamyl acetate, menthol laevo, methyl cinnamate, methyl salicylate, orange oil, rosemary oil, tarragon, Tea Tree oil, and peppermint oil; and one or more antimicrobial agents selected from the group comprising triclosan, pyrophosphates, zinc salts, cetylpyridinium chloride, parabens, stannous salts, sodium dodecyl sulphate, chlorhexidine, copper salts, strontium salts, peroxides and sanguinarine.
Owner:QUEST INTERNATIONAL

Biological complex enzyme toothpaste and preparation method thereof

The invention relates to biological complex enzyme toothpaste and a preparation method thereof. The toothpaste is prepared from the following components by weight percentage: 5-10% of sorbierite, 15-20% of hydrous silica, 10-20% of aluminum hydroxide, 10-20% of glycerin, 2-3% of sodium lauroyl sarcosine, 1-1.3% of flavor, 0.8-1.2% of cellulose gum, 0.3-0.6% of carrageenin, 0.3-0.5% of droxyethylcellulose, 0.5-1.2% of sodium phytate, 0.15-0.3% of saccharin sodium, 0.3-0.5% of strontium chloride, 0.1-0.3% of trisodium phosphate, 0.00003-0.00008% of staphylococcus lysozyme, 0.00005-0.00015% of muramidase, 0.00001-0.00004% of proteolytic enzyme, 0.00002-0.00005% of glycosidic hydrolase, 0.00002-0.00005% of peroxydase, 0.08-0.15% of borneol, 0.1-0.15% of borax, 0.08-0.1% of vermilion, 0.1-0.15% of natrii sulfas exsiccatus, 0.05-0.1% of triclosan, 0.1-0.4% of allantoin, and the balance of water. The total weight percentage of the components is 100%. The biological complex enzyme toothpaste has complete function.
Owner:JIANGSU XUE BAO DAILY CHEM CO

Cleaning-free hand sanitizer and preparation thereof

The invention relates to a disinfectant, in particular to a cleaning-free hand sanitizer and preparation thereof. The cleaning-free hand sanitizer comprises the following components: 47%-56% of absolute ethanol, 0.001%-0.3% of triclosan, 0.1%-0.3% of Carbomer U20, 0.01%-2% of sodium hyaluronate, 0.01%-10% of glycerin, 0.02%-0.11% of an acid-base modifier, 0.01%-1% of nursing modifier and 20%-50% of deionized water. The cleaning-free hand sanitizer can be widely applied to daily life and has good sterilization effect and low skin harm property, thus being applicable to disinfection, sterilization and bactriostasis on the surface of skin and objects for preventing contact infectious diseases.
Owner:上海绿色建材研究中心有限公司

Antibiotic paint and method for preparing the same

The invention relates to antibacterial paint and a production process, which comprises raw materials with following parts by weight of 1-10 parts of antibacterial agent. 2-30 parts of organic silicate, 10-40 parts of silane coupling agent and 40-90 parts of water, wherein antibacterial agent is triclosan and pyridine thione. The preparation process comprises adding water with required quantity in a liquid mixing container, adding organic silicate with required quantity into water, adding silane coupling agent after evenly agitated, continuing to agitate to make solution evenly mix, adding anti-bacterial agent of triclosan and pyridine thione, and continuing to agitate for 20 minutes. The invention solves the technical problem that fungicide and addition agent which are adopted by current anti-bacterial paint can affect environment and the health of persons, and has significant mildew proof, anti-bacterial and bacterial inhibiting property. And anti-bacterial material which is adopted belongs to no toxic material, has no harmful affect to environment and human health, and can realize anti-bacterial effect with long-term and high efficiency.
Owner:CHINA BANKNOTE PRINTING & MINTING

Compositions for the relief of xerostomia and the treatment of associated disorders

New liquid compositions are described for the relief of the xerostomia and the treatment of associated disorders, in which the compositions contain: a) saline saliva substitute agents selected from the group consisting of sodium chloride, potassium chloride, sodium bicarbonate, monobasic potassium phosphate, and dibasic phosphate potassium; b) saliva production stimulation agents selected from the group consisting of citric acid or its alkali metal salts and malic acid or its alkali metal salts; c) oral antiseptics selected from the group consisting of triclosan, chlorhexidine and its salts, benzalkonium and its salts, and cetylpyridinium chloride; d) anticariogenic agents selected from the group consisting of fluoride sodium, sodium monofluorophosphate, and xylitol; and e) oral mucosa protective agents selected from the group consisting of vitamin E acetate, panthenol, dipotassium glycyrrhizinate and extracts of aloe vera.The aforementioned compositions are presented in the form of mouthwashes, sprays, oral gels, and toothpastes.
Owner:LACER SA

Chlorhexidine acetate antiseptic cleaning agent

ActiveUS8343525B2Efficient growth processKilling or preventing/impeding pathogen growthCosmetic preparationsBiocidePolyesterTriclosan
An antiseptic cleaning agent, generally, comprising chlorhexidine acetate and a solvent, such as an alcohol and / or water. The chlorhexidine acetate acts as a highly effective biocide. Additionally, the chlorhexidine acetate allows the cleaning agent to dry without leaving a tacky residue. Where the cleaning agent comprises one or more alcohols, the alcohols may comprise any suitable alcohols, including lower alcohols having from 1 to 6 carbon atoms, such as ethanol and isopropanol. Where the ratio of ethanol to isopropanol may be from between about 1:1000 to about 1000:1. In addition to chlorhexidine acetate, the cleaning agent optionally comprises another non-alcohol biocide, such as triclosan. The cleaning agent can be used in any suitable manner. For instance, the cleaning agent may be impregnated in an absorbent material, such as a towelette, swabstick, or gauze. Additionally, the absorbent material may comprise a positively charged or a non-ionic substance, such as polypropylene or polyester.
Owner:BECTON DICKINSON & CO

Viricidal composition

A non-staining composition which is bactericidal, fungicidal and viricidal when applied, comprising in combination; an iodine free bactericide and / or fungicide having a residual efficacy lasting longer than 3 hours on surfaces against bacteria and fungi and a peroxide. A carrier may also be present. The bactericide and / or fungicide may be for example triclosan or a quaternary ammonium compound, or preferably a PVP-phenolic biocide complex (eg PVP-triclosan) or PVAIc / quaternary ammonium compound complex (eg PVP / benzalkonium chloride). The peroxide may be hydrogen peroxide.
Owner:NOVAPHARM RES AUSTRALIA
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