37 results about "Sebum production" patented technology

The present invention relates to acne and rosacea compositions by a six-prong synergistic combination treatment strategy that includes (1) control of excess sebum production, (2) control of undesirable bacteria or mites, (3) control of inflammation, (4) enhanced desquamation of follicular infundibulum cells, (5) reduction of irritation from anti-acne or rosacea compositions themselves, and (6) enhancement of the topical bioavailability of anti-acne and rosacea compositions. This is achieved by a synergistic combination of commonly utilized topical anti-acne and rosacea ingredients with a topical bioavailability enhancement composition, which results in enhanced anti-acne and rosacea action from such ingredients. Moreover, additional inclusion of an anti-inflammatory composition, and also a vascular micro-circulation enhancement composition, further results in synergistic superior anti-acne and rosacea benefits from such compositions. The present invention discloses additional surprising synergistic combinations for the control of acne and rosacea that are suitable for a variety of delivery systems and packaging forms.

Provided herein are methods of using gaseous nitric oxide and/or at least one nitric oxide source to or decrease sebum production in the skin of a subject. In some embodiments, the nitric oxide source includes small molecule and/or macromolecular NO-releasing compounds.

An improved method, formulation and kit for the treatment of acne vulgaris are disclosed. The formulation is effective in inhibiting or killing the Proprionibacterium microorganism without utilizing antibiotics A preferred formulation alleviates the four pathogenic factors involved in the development of acne a) the putative pathogen of acne, Proprionibacterium acnes, b) abnormal desquamation of sebaceous-follicle epithelium (comedogenesis), c) the androgen-induced excessive sebum production, and d) the follicular reactivity (inflammation). The formulations are preferably applied as a cream, lotion or an emulsion.

Halosalicylic acid compounds of the present invention, having at least one halogen substituent on the aromatic ring, are employed to produce desquamation of skin, treat nail disorders or dandruff, remove calluses, control acne and excess sebum production, reduce skin pore size or control blackheads. Topical compositions containing the halosalicylic acid compound and a cosmetically acceptable vehicle are disclosed.

Disclosed herein are topical dermal compositions comprising particles, wherein the particles comprise

a) a biodegradable polymer, and

b) a retinoid selected from the group consisting of:

or a pharmaceutically acceptable salt thereof, wherein the particles have an average diameter between 0.1 μm and 10 μm, and wherein the variables are as defined in the specification. The compositions are useful for treating a condition associated with excess sebum production.

The present invention is directed to the topical application of the malonamide ACAT inhibitors described by Formula I. Other aspects of the invention are directed to topical formulations of these diamides, their use to treat sebaceous gland disorders and their use to alleviate oily skin.

Compositions that include Psidium guajava fruit extract or Kunzea ericoides leaf extract or both for reducing sebum production in sebaceous glands are disclosed.

Cosmetic compositions and methods of decreasing sebum production and/or pore size by contacting skin with a hair growth inhibitor, including polyamine derivatives and/or analogs; DFMO, N-acetyl cysteines; neutralized salts of a non-hydroxy C2-C40 dicarboxylic acids, preferably malonate salts; and mixtures thereof. Additional sebum and/or pore size reducing agents, such as carboxyalkylates of branched alcohols and/or ethoxylates thereof, cerulenin, triclosan, α-methylene-γ-butyrolactone, and EGCG, as well as mixtures thereof and analogs thereof, may be included in the inventive compositions and methods.

A method for treatment of acne by applying to human skin a topical composition. The method involves contacting the human skin of area of an afflicted subject with an effective amount of the composition containing chromium and magnesium sulfate, for a period of time sufficient to reduce the redness and blemishes associated with acne. The topical composition is formulated into a pharmaceutically acceptable medium to properly regulate the keratin and sebum production of the skin cells, thereby inhibiting the appearance of acne therefore. The preferred use of the foregoing composition and method is in the treatment of acne.

The present disclosure provides compositions comprising fatty acids, or derivatives thereof (e.g., C1-C4 esters) including, for example, DGLA, 15-OHEPA and/or 15-HETrE, used singly or in combination with anti-bacterial agents for the inhibition of sebum production.

The present invention relates to a peptide exhibiting physiological activities and a composition including the peptide. Because the peptide of the present invention exhibits various physiological activities such as muscle relaxation, skin wrinkle improvement, sebum production suppression, and the like, the peptide may be used as an active ingredient in a pharmaceutical composition for muscle relaxation, or cosmetics for improving skin wrinkles, suppressing sebum production, or ameliorating acne.

The invention relates to the use of arjunolic acid for increasing sebum production, and to preparations comprising arjunolic acid and 1,2-pentanediol.

Pharmaceutical, odontological, cosmetic and dermatological compositions comprising addition salts of trichloroacetic acid, one or more hydroxyacids and optionally glutamic acid or glutamic acid bioisosteres and phytic acid are useful for the peeling of the gingival collar, skin peeling, for resurfacing, treating skin hyper pigmentation, control sebum production, acne, pore size reduction and reducing the appearance of scars without causing undesirable side effects and contrast in coloration of the treated skin, for stimulation of the fibroblasts, transdermal biorevitalization, stimulation of the production of new collagen, for aesthetic improvement, for skin lightening, skin beautifying, skin firming and skin rejuvenation.

The invention discloses a processing technology of a lavender paper diaper. The technology comprises the steps of lavender collection, lavender drying, lavender powder processing, flow guide layer chopping, waist-surrounding non-woven fabric slitting, cavity transferring and packaging processing. The process has rigorous steps, a lavender powder is arranged, and the lavender powder is fixed between the upper package and the lower package in a bonding mode. Under the action of the lavender, the paper diaper is suitable for any skin, promotes cell regeneration, accelerates wound healing, improves acne, abscess and eczema, balances sebum secretion, can inhibit bacteria, reduces peculiar smell of paper diapers, increases the multifunctionality of paper diapers, and improves the wearing comfortof infants.

A composition for reducing sebum production in the skin of a user, the composition comprising:

• • a liquid carrier; and
  • Pyridoxine Cyclic Phosphate;
  • wherein the Pyridoxine Cyclic Phosphate is present in the composition in a concentration sufficient to reduce sebum production in the skin of a user when the composition is applied to the skin of a user.

The invention discloses a novel gulcomannan heteroglycan peptide and a preparation method and application thereof.The novel gulcomannan heteroglycan peptide is a fermentation product of alpha-hemolytic streptococcus 33 # and is separated and purified through a concentration and alcohol precipitation method and an ultrafiltration method to obtain uniform polysaccharide peptide, and the structure of the novel gulcomannan heteroglycan peptide is identified through physical and chemical analysis; the monosaccharide composition of the novel gulcomannan heteroglycan peptide comprises mannose, rhamnose and glucose in a molar ratio of 8.22: 1: 6.46, the weight-average molecular weight of the novel gulcomannan heteroglycan peptide is 10045Da, and the molecular weight distribution coefficient of the novel gulcomannan heteroglycan peptide is 1.31; when applied to acne-removing cosmetics, the acne-removing essence has an obvious moisturizing effect, is relatively long in moisturizing time, has an effect of inhibiting propionibacterium acnes in engine oil, achieves the effects of diminishing inflammation and removing acnes, and can balance sebum secretion on the surface of human skin, so that the repaired skin can be fuller, and the residue of acne marks is reduced; skin surface looseness and pore blockage can be avoided.