37 results about "Sebum production" patented technology

The present invention relates to acne and rosacea compositions by a six-prong synergistic combination treatment strategy that includes (1) control of excess sebum production, (2) control of undesirable bacteria or mites, (3) control of inflammation, (4) enhanced desquamation of follicular infundibulum cells, (5) reduction of irritation from anti-acne or rosacea compositions themselves, and (6) enhancement of the topical bioavailability of anti-acne and rosacea compositions. This is achieved by a synergistic combination of commonly utilized topical anti-acne and rosacea ingredients with a topical bioavailability enhancement composition, which results in enhanced anti-acne and rosacea action from such ingredients. Moreover, additional inclusion of an anti-inflammatory composition, and also a vascular micro-circulation enhancement composition, further results in synergistic superior anti-acne and rosacea benefits from such compositions. The present invention discloses additional surprising synergistic combinations for the control of acne and rosacea that are suitable for a variety of delivery systems and packaging forms.

Provided herein are methods of using gaseous nitric oxide and / or at least one nitric oxide source to or decrease sebum production in the skin of a subject. In some embodiments, the nitric oxide source includes small molecule and / or macromolecular NO-releasing compounds.

Cosmetic compositions and methods of decreasing sebum production by contacting sebocytes with a fatty acid synthase inhibitor, including cerulenin, triclosan, α-methylene-γ-butyrolactone, and EGCG, as well as mixtures thereof and analogs thereof. The invention further relates to a cosmetic method of identifying sebum production inhibiting actives comprising contacting the active with FAS and detecting a reduction in sebum amount production in sebocytes.

The present invention relates to a nutritional product, dietary supplement or pharmaceutical composition for the treatment of acne and related skin disorders. The invention also relates to a composition having a combination of ingredients such that it reduces symptoms associated with acne and related skin disorders. The invention relates to such a composition containing a variety of vitamins, minerals and one or more herbal medicine sources. In one preferred embodiment, the vitamins, minerals and one or more herbal medicine sources are present in an amount such that its mechanism of action is through inhibition of the growth of Propionobacterium acnes (P. acnes) and the inhibition of lipogenesis of sebum production. In another preferred embodiment, the invention contains a Vitamin A source to normalize keratinoid maturation, proliferation and turnover of skin cells. In another preferred embodiment, the invention further contains at least one of a Vitamin E source or Selenium. In another preferred embodiment, the invention further contains at least one of a Vitamin B6 source, a Pantothenic Acid source, Zinc or any active salt, and Chromium or any active salt. In another preferred embodiment, the invention further contains any one or more of an herbal source of Berberis aquifolium (Oregon grape root), Barberis vulgaris (barberry), Hydrastis Canadensis (goldenseal), or other herbal source of the compound berberine. The present invention also relates to a method of administering a therapeutically effective amount of the combination of ingredients for the treatment of acne and related skin disorders.

A muscarinic receptor antagonist is useful for the treatment or prevention of a condition associated with excess sebum production or excretion.

An improved method, formulation and kit for the treatment of acne vulgaris are disclosed. The formulation is effective in inhibiting or killing the Proprionibacterium microorganism without utilizing antibiotics A preferred formulation alleviates the four pathogenic factors involved in the development of acne a) the putative pathogen of acne, Proprionibacterium acnes, b) abnormal desquamation of sebaceous-follicle epithelium (comedogenesis), c) the androgen-induced excessive sebum production, and d) the follicular reactivity (inflammation). The formulations are preferably applied as a cream, lotion or an emulsion.

Halosalicylic acid compounds of the present invention, having at least one halogen substituent on the aromatic ring, are employed to produce desquamation of skin, treat nail disorders or dandruff, remove calluses, control acne and excess sebum production, reduce skin pore size or control blackheads. Topical compositions containing the halosalicylic acid compound and a cosmetically acceptable vehicle are disclosed.

Disclosed herein are topical dermal compositions comprising particles, wherein the particles comprisea) a biodegradable polymer, andb) a retinoid selected from the group consisting of:or a pharmaceutically acceptable salt thereof, wherein the particles have an average diameter between 0.1 μm and 10 μm, and wherein the variables are as defined in the specification. The compositions are useful for treating a condition associated with excess sebum production.

The present invention is directed to the topical application of the malonamide ACAT inhibitors described by Formula I. Other aspects of the invention are directed to topical formulations of these diamides, their use to treat sebaceous gland disorders and their use to alleviate oily skin.

Compositions that include Psidium guajava fruit extract or Kunzea ericoides leaf extract or both for reducing sebum production in sebaceous glands are disclosed.

An improved method, formulation and kit for the treatment of acne vulgaris are disclosed. The formulation is effective in inhibiting or killing the Proprionibacterium microorganism without utilizing antibiotics A preferred formulation alleviates the four pathogenic factors involved in the development of acne a) the putative pathogen of acne, Proprionibacterium acnes, b) abnormal desquamation of sebaceous-follicle epithelium (comedogenesis), c) the androgen-induced excessive sebum production, and d) the follicular reactivity (inflammation). The formulations are preferably applied as a cream, lotion or an emulsion.

A method for treatment of acne by applying to human skin a topical composition. The method involves contacting the human skin of area of an afflicted subject with an effective amount of the composition containing chromium and magnesium sulfate, for a period of time sufficient to reduce the redness and blemishes associated with acne. The topical composition is formulated into a pharmaceutically acceptable medium to properly regulate the keratin and sebum production of the skin cells, thereby inhibiting the appearance of acne therefore. The preferred use of the foregoing composition and method is in the treatment of acne.

Sebum production inhibitors containing as an active ingredient a compound of general formula (1) below having a glucuronic acid derivative and a glucosamine derivative in the structure or a pharmacologically acceptable salt thereof

The present invention relates to a composition containing a material for regulating the expression of ABH antigens and, more specifically, to a composition capable of: controlling sebum production and alleviating skin trouble by regulating the expression of ABH antigens; preventing skin pore enlargement by providing antioxidant effects; and defending against skin irritation production.

The present invention discloses cosmetic compositions based on phytic acid and used for skin resurfacing, treating hyper pigmentation, control sebum production, for pore size reduction and combating acne and a method of application. The trichloroacetic acid can be added to the composition, containing phytic acid for more deep peels. The compositions and the methods of application of the composition containing phytic acid and the composition, containing trichloroacetic acid and phytic acid are claimed.

The present disclosure provides compositions comprising fatty acids, or derivatives thereof (e.g., C1-C4 esters) including, for example, DGLA, 15-OHEPA and / or 15-HETrE, used singly or in combination with anti-bacterial agents for the inhibition of sebum production.

The invention discloses an oil-control moisturizing hair composition containing double proteins. The hair composition disclosed by the invention is prepared from mango leaf extract, zinc lactate and zinc gluconate, and wheat protein, silk protein and panthenol can be further supplemented, so that the effects of controlling oil and preserving moisture are achieved. The hair composition can be applied to hair washing and caring products with a grease balancing function, such as oil-control shampoo or hair conditioner, and after the hair composition is used, grease secretion can be effectively controlled, and sebum production can be inhibited. The hair composition has multiple effects of balancing grease secretion, inhibiting bacteria, preserving moisture, relieving itching and the like, can remarkably improve the hair quality, soften the hair and repair the hair, and can simultaneously realize the effects of controlling oil and preserving moisture of scalp and softening the hair.

The present invention is directed to the topical application of the malonamide ACAT inhibitors described by Formula I. Other aspects of the invention are directed to topical formulations of these diamides, their use to treat sebaceous gland disorders and their use to alleviate oily skin.

The present invention provides topical dermal compositions including microsphere encapsulated isotretinoin. Pharmaceutically acceptable salts, esters, or amides of isotretinoin are also contemplated for use in the practice of the invention. The compositions of the invention are useful for treating a variety of conditions associated with excess sebum production, such as, for example, acne.

The present invention relates to a composition for sebum control and pore minimizing and, more specifically, to an external use skin preparation composition comprising, as an active ingredient, extracts of one or more medicinal herbs selected from the group consisting of Cimicifugae rhizoma, Solani nigri herba, Glycyrrhizae radix, Clematis chinensis osbeck, Acanthopanax senticosus, Inulae radix and Dioscorea japonica, and thus sebum production can be controlled, skin problems can be alleviated, antioxidant effects are provided, pore enlargement is prevented, and the occurrence of skin irritation is defended against.

The present invention relates to a peptide exhibiting physiological activities and a composition including the peptide. Because the peptide of the present invention exhibits various physiological activities such as muscle relaxation, skin wrinkle improvement, sebum production suppression, and the like, the peptide may be used as an active ingredient in a pharmaceutical composition for muscle relaxation, or cosmetics for improving skin wrinkles, suppressing sebum production, or ameliorating acne.

The invention relates to the use of arjunolic acid for increasing sebum production, and to preparations comprising arjunolic acid and 1,2-pentanediol.

Pharmaceutical, odontological, cosmetic and dermatological compositions comprising addition salts of trichloroacetic acid, one or more hydroxyacids and optionally glutamic acid or glutamic acid bioisosteres and phytic acid are useful for the peeling of the gingival collar, skin peeling, for resurfacing, treating skin hyper pigmentation, control sebum production, acne, pore size reduction and reducing the appearance of scars without causing undesirable side effects and contrast in coloration of the treated skin, for stimulation of the fibroblasts, transdermal biorevitalization, stimulation of the production of new collagen, for aesthetic improvement, for skin lightening, skin beautifying, skin firming and skin rejuvenation.

A composition containing a material for regulating the expression of ABH antigens and, more specifically, to a composition capable of: controlling sebum production and alleviating skin trouble by regulating the expression of ABH antigens; preventing skin pore enlargement by providing antioxidant effects; and defending against skin irritation production and method of using the composition are disclosed.

The invention discloses a processing technology of a lavender paper diaper. The technology comprises the steps of lavender collection, lavender drying, lavender powder processing, flow guide layer chopping, waist-surrounding non-woven fabric slitting, cavity transferring and packaging processing. The process has rigorous steps, a lavender powder is arranged, and the lavender powder is fixed between the upper package and the lower package in a bonding mode. Under the action of the lavender, the paper diaper is suitable for any skin, promotes cell regeneration, accelerates wound healing, improves acne, abscess and eczema, balances sebum secretion, can inhibit bacteria, reduces peculiar smell of paper diapers, increases the multifunctionality of paper diapers, and improves the wearing comfortof infants.

A composition for reducing sebum production in the skin of a user, the composition comprising:a liquid carrier; andPyridoxine Cyclic Phosphate;wherein the Pyridoxine Cyclic Phosphate is present in the composition in a concentration sufficient to reduce sebum production in the skin of a user when the composition is applied to the skin of a user.

The invention discloses a novel gulcomannan heteroglycan peptide and a preparation method and application thereof.The novel gulcomannan heteroglycan peptide is a fermentation product of alpha-hemolytic streptococcus 33 # and is separated and purified through a concentration and alcohol precipitation method and an ultrafiltration method to obtain uniform polysaccharide peptide, and the structure of the novel gulcomannan heteroglycan peptide is identified through physical and chemical analysis; the monosaccharide composition of the novel gulcomannan heteroglycan peptide comprises mannose, rhamnose and glucose in a molar ratio of 8.22: 1: 6.46, the weight-average molecular weight of the novel gulcomannan heteroglycan peptide is 10045Da, and the molecular weight distribution coefficient of the novel gulcomannan heteroglycan peptide is 1.31; when applied to acne-removing cosmetics, the acne-removing essence has an obvious moisturizing effect, is relatively long in moisturizing time, has an effect of inhibiting propionibacterium acnes in engine oil, achieves the effects of diminishing inflammation and removing acnes, and can balance sebum secretion on the surface of human skin, so that the repaired skin can be fuller, and the residue of acne marks is reduced; skin surface looseness and pore blockage can be avoided.