235 results about "Oxidation Activity" patented technology

The invention relates to an anti-oxidation composition based on a reverse micelle synergistic technology and a preparation method and application thereof, the anti-oxidation composition comprises a reverse micelle structure and an aqueous solution containing an anti-oxidation active matter, and the reverse micelle structure wraps the aqueous solution containing the anti-oxidation active matter. The reverse micelle structure is used for wrapping the water-soluble antioxidant active matter, oxidation or degradation discoloration of the water-soluble antioxidant active matter is prevented, after the antioxidant active matter such as hydroxytyrosol, ergothioneine and dipotassium glycyrrhizinate is wrapped by the reverse micelle, the stability and the effect are remarkably improved, and after the reverse micelle wrapping, the effect of the antioxidant active matter is improved by 17% or above compared with an aqueous solution before wrapping.

The invention discloses polypeptide hydrogel based on oxidized ganoderan and application. The polypeptide hydrogel is simple in preparation method, rapid in gelling, good in stability and capable of resisting oxidation activity and inhibiting tyrosinase activity. The polypeptide hydrogel provides a physical barrier for the bioactive peptide, so that the influence of the gastrointestinal tract environment is overcome, 71% of polypeptide is released in the intestinal tract, the bioavailability of the peptide is improved, and the problem that the use condition of the polypeptide is limited is effectively solved.

The invention discloses a nano-carbon supported ruthenium cluster nano-catalyst as well as a preparation method and application thereof. According to the present invention, the synthesis process of the catalyst is simple and easy to perform, the reaction process is controllable, the nanocarbon with characteristics of rich defects and large specific surface area is adopted as the carrier, the ruthenium cluster is loaded on the surface of the nanocarbon, and the nanometer catalyst with characteristics of high specific surface area and high atom utilization rate is synthesized. The catalyst can catalyze persulfate (PDS) to generate products with strong oxidation activity, namely sulfate free radicals (SO4.-), hydroxyl free radicals (. OH) and singlet oxygen (1O2), so that effective inactivation of bacteria is realized. In the invention, the reaction of activating the persulfate to disinfect by the catalyst is carried out at room temperature under neutral conditions, and in a mild reaction environment, the nanocarbon-loaded ruthenium cluster nanocatalyst shows good capability of catalyzing the persulfate to inactivate bacteria, and has huge potential in practical application of water disinfection.

The invention discloses a manganese-containing denitration catalyst and a preparation method thereof, and the preparation method comprises the following steps: 1) adding a manganese source precursor solution and a basic hydroxide solution into a potassium permanganate solution to obtain a mixed solution; continuously stirring the mixed solution at 20-80 DEG C for more than 0.5 h, and then carrying out solid-liquid separation to obtain an initial solid; drying the initial solid to obtain an active manganese oxide; and 2) mixing 30-70 parts by weight of active manganese oxide, 3-12 parts by weight of an active auxiliary agent, 0.5-8 parts by weight of a molding auxiliary agent and 1-6 parts by weight of a pore-forming agent, wetting, kneading, molding, and drying to obtain the manganese-containing denitration catalyst. The manganese-containing denitration catalyst prepared by the preparation method disclosed by the invention has NO low-temperature oxidation activity and relatively good water resistance and sulfur resistance.

The invention discloses a high-entropy metal oxide catalyst as well as a preparation method and application thereof in CO catalytic oxidation, and belongs to the technical field of flue gas treatment. The preparation method comprises the following steps: dissolving copper salt, manganese salt, cerium salt, cobalt salt, vanadium salt and a dispersing agent into water to form a uniform solution, and slowly adding excessive alkali precipitant into the uniform solution to form a solid-liquid mixture; the solid-liquid mixture is transferred into a high-pressure kettle to be subjected to a hydrothermal reaction and then quenched, an obtained hydrothermal reaction product is calcined, and the high-entropy metal oxide catalyst is obtained and is high in catalytic oxidation activity on carbon monoxide at the low temperature, excellent in water resistance and sulfur resistance and particularly suitable for treatment of complex flue gas.

The invention relates to a lipase mutant and application thereof in preparation of epoxide, in particular to a lipase mutant which is derived from Tilletia indica and has remarkably improved peroxidation activity, a coding nucleic acid of the lipase mutant, a recombinant expression vector and a recombinant expression transformant containing a nucleic acid sequence, and an application of the lipase mutant in preparation of epoxide. The recombinant lipase or the recombinant expression transformant is used as a catalyst for preparing peroxy acid, and the peroxy acid reacts with olefin to generate epoxide. Compared with other methods (including a chemical method or a biological method and the like) for preparing alpha-epoxy pinane, the enzyme and the technical method thereof disclosed by the invention have the advantages of mild reaction conditions, environmental friendliness, lower cost, simplicity and convenience in operation, easiness in amplification and the like, and have a very good application prospect in the field of producing epoxy products by taking carbon-carbon double bonds as substrates.

The present invention discloses a Nitrospira The invention relates to nitrite oxidizing bacteria and their applications, belonging to the field of microbial and environmental protection technology. The strain is named Nitrospira sp. Z02, with a deposit number of GDMCC No: 66050, and was deposited in Guangdong Provincial Microbial Culture Collection Center on March 25, 2025. The strain is a new species, belongs to chemoautotrophic type, and expands Nitrospira The strains are diverse and can oxidize nitrite under different oxygen concentrations, have good adaptability to oxygen concentrations, retain oxidation activity within the pH range of 5.5 to 8.5, and can tolerate weakly acidic conditions. They can grow on solid plates and have the potential for molecular modification. Therefore, this strain has good application value in the treatment of nitrite-containing wastewater.

The invention provides a lactobacillus gasseri strain A21120 with anti-oxidation, anti-inflammatory and anti-tumor functions as well as a probiotic agent and application of the lactobacillus gasseri strain A21120, and belongs to the technical field of functional microorganisms. The strain A21120 is separated and screened from intestinal feces of healthy old people of 100 years old, and belongs to lactobacillus gasseri through morphological identification and molecular identification. The strain has good gastrointestinal fluid resistance and bovine choline resistance and has the potential of colonizing intestinal tracts. The lactobacillus gasseri strain A21120 provided by the invention has bacteriostatic activity, anti-inflammatory activity, anti-oxidation activity and anti-tumor activity, and provides a new way for treatment of clinical related diseases, drug development and preparation of in-vitro preparations or daily necessities.

The invention relates to the technical field of biological agents, in particular to abalone-derived polypeptide with antioxidant activity and a preparation method thereof. According to the invention, Haliotis discus hannai Ino is taken as a research object, a small peptide library is established by using a virtual enzymolysis technology from an important anti-oxidation pathway of cells, namely a Keap1-Nrf2 pathway, an abalone-derived anti-oxidation peptide DEDEDEDK with relatively strong binding capacity with Keap1 is screened out by using a molecular docking technology, and then, the anti-oxidation activity of the abalone-derived anti-oxidation peptide DEDEDEDK is verified by using a cell oxidative damage model, so that the abalone-derived anti-oxidation peptide DEDEDEDK can be used for preparing the anti-oxidation peptide DEDEDEDK with relatively strong binding capacity with Keap1. And a theoretical basis is provided for research and application of the antioxidant peptide.

The invention belongs to the technical field of biological culture, and particularly relates to a chlorella extracellular fluid and a preparation method and application thereof.The preparation method of the chlorella extracellular fluid comprises the following steps that a BG11 culture medium is inoculated with a chlorella solution cultured to the logarithmic phase, oxcarbazepine is added, and the chlorella extracellular fluid is obtained; the preparation method comprises the following steps: placing chlorella in an intermittent illumination environment with the temperature of 20-30 DEG C and the rotating speed of 100-200 rpm for growth, centrifuging the chlorella to obtain supernate after the chlorella grows to the 10th-16th day, filtering, sub-packaging, and performing cryopreservation to obtain the chlorella extracellular fluid. By adding oxcarbazepine, the chlorella extracellular fluid prepared in a specific culture medium and a specific growth environment has high oxidation activity, excellent stability and excellent degradation capacity, and a new thought is provided for solving the pollution treatment problem of current environmental pollutants such as pharmaceutical products, polycyclic aromatic hydrocarbons and dyes.

The present invention discloses a method for regulating spinel-type high-entropy oxides using electrospinning. The method is characterized in that metal sources, polyacrylonitrile, and dimethylformamide of varying concentrations are fully mixed to form a precursor solution, followed by preparing a spinel-type high-entropy oxide having a nanofiber structure by electrospinning. Results show that, compared to conventional methods for preparing high-entropy oxides, electrospinning facilitates a lower phase transition temperature and promotes the formation of nanoscale high-entropy oxides. Furthermore, the fibers formed are significantly affected by the precursor solution. By varying the amount of total metal added, the final fiber state of the catalyst can be effectively regulated, exhibiting significant differences in ethyl acetate catalytic oxidation activity. The preparation process is simple, enhancing the application value of high-entropy oxides in the field of heterogeneous catalysis.

The invention provides a carrier material for supporting a protein drug. The carrier material comprises an inner core, a calcium carbonate coating layer coating the inner core and a polyethylene glycol-polyglutamic acid diblock copolymer chain segment anchored on the coating layer. The intracellular protein delivery carrier provided by the invention can effectively support various metal ions and protein drugs with the Fenton / Fenton-like reaction catalysis effect, and after the intracellular protein delivery carrier is endocytosed by cells, the protein drugs, calcium ions and the metal ions with the Fenton / Fenton-like reaction catalysis effect are released; metal ions can catalyze hydrogen peroxide in the endosome / lysosome to generate hydroxyl radicals with high oxidation activity, lipid molecules are oxidized, and a lysosome membrane is destroyed; the released calcium ions can cause mitochondrial calcium overload, improve the level of hydrogen peroxide in cells, promote generation of hydroxyl radicals in endosome / lysosome and damage of membranes of the hydroxyl radicals, induce efficient rupture of the endosome / lysosome and deliver protein drugs into cytoplasm so as to play the functions of the protein drugs.

The invention discloses a preparation method of a catalytic oxidation peroxyacetic acid self-release oxygen membrane and application thereof in the field of water treatment, and belongs to the technical field of water pollution control. The invention aims to solve the problems of unbalanced release rate and oxidation activity, self-decomposition loss of an oxidant, secondary pollution risk, and insufficient dynamic cleaning and long-acting anti-pollution capability in the traditional oxygen release technology. According to the invention, peroxyacetic acid is taken as an oxidizing agent, and a self-oxygen-release membrane for catalytic oxidation of peroxyacetic acid is taken as a catalyst, so that an oxygen-release membrane system is constructed, the water treatment efficiency and membrane performance are remarkably improved, the operation energy consumption of the system is greatly reduced, and an innovative solution is provided for development of an intelligent water treatment technology. The method has wide application scenarios, and is suitable for different water quality and treatment requirements. The high-efficiency degradation capability on pollutants such as antibiotics and endocrine pollutants is realized, the high-efficiency interception on complex pollutants such as humic acid, protein and colloid is realized, and the high-efficiency degradation capability is suitable for water supply sources, municipal sewage, industrial wastewater and reclaimed water treatment scenes.

The invention belongs to the technical field of sulfur recovery, and particularly relates to an organic sulfur hydrolysis synergistic sulfur recovery catalyst as well as a preparation method and application thereof. Comprising the following steps: (1) dissolving strontium salt; (2) adding transition metal salt; (3) adding a titanium source; (4) adding an alkali metal compound; (5) stirring reaction; (6) hydro-thermal treatment; and (7) centrifuging, washing, drying and roasting. The general formula of the prepared catalyst is SrTi (1-x) MxO3, in the formula, x is equal to 0.05-0.2, and M is a transition metal element. The prepared catalyst is high in material composition and structure adjustability, rich in surface acid-base sites, excellent in organic sulfur hydrolysis reaction activity and H2S selective oxidation activity, and capable of realizing efficient and synergistic proceeding of organic sulfur hydrolysis and H2S selective oxidation and removing sulfur-containing components in process gas in one step.

The invention provides liquorice seed oil as well as a preparation method and application thereof, and relates to the field of vegetable oil extraction. The preparation method of the licorice seed oil comprises the following steps: crushing licorice seeds to obtain licorice seed powder; extracting the licorice seed powder with n-hexane, and concentrating under reduced pressure to obtain crude oil; and refining the crude oil to obtain the licorice seed oil. The invention further provides application of the liquorice seed oil in preparation of anti-tumor or anti-cancer drugs, preparation of health-care foods or drugs with anti-inflammatory activity and preparation of health-care foods or drugs with anti-oxidation activity. The method is of great significance to utilization and popularization of liquorice seed resources.

The invention relates to a high-stability palladium-based molecular sieve catalyst as well as a preparation method and application thereof. The high-stability palladium-based molecular sieve catalyst comprises an SSZ-13 hydrophobic modified molecular sieve and an active component loaded on the SSZ-13 hydrophobic modified molecular sieve, the active component comprises palladium oxide particles; based on 100 wt% of the total mass of the high-stability palladium-based molecular sieve catalyst, the content of the active component in the high-stability palladium-based molecular sieve catalyst is 0.5 wt%-5 wt%. According to the high-stability palladium-based molecular sieve catalyst, an SSZ-13 hydrophobic modified molecular sieve is used as a carrier, so that the adsorption capacity of the catalyst to water is weakened, the purpose of reducing water poisoning inactivation of palladium oxide substances is achieved, inactivation of the palladium oxide substances under the high-temperature hydrothermal condition is avoided, and the methane catalytic oxidation activity, the hydrothermal aging performance and the stability of the catalyst are obviously improved.

The invention discloses recombinant human VII type collagen as well as a preparation method and application thereof, and belongs to the technical field of biochemical engineering. The recombinant human VII type collagen comprises a plurality of amino acid residue repetitive units shown as SEQ ID NO.1. Compared with natural VII type collagen, the recombinant human VII type collagen obtained by repeating the repetitive units for multiple times has the advantages that the molecular weight is smaller, the sequence is more easily and efficiently secreted and expressed in a pichia pastoris system after optimization, and the recombinant human VII type collagen can be used for preparing the recombinant human VII type collagen. The method has the characteristics of high yield, low cost, simplicity in operation and easiness in large-scale production. Meanwhile, the anti-oxidation activity is excellent, the skin moisturizing and repairing capacity and the wound healing capacity are promoted, due to the fact that the collagen is derived from human collagen, the risks of allergy and rejection reaction can be remarkably reduced, and the safety is extremely high. Therefore, the recombinant collagen can be used as a core active component to be widely applied to the fields of cosmetics, medicines and the like, and has a good application prospect.

The invention relates to a transition metal nickel monatomic difunctional electrocatalyst and a preparation method and application thereof, and belongs to the technical field of carbon dioxide electrolysis. The catalyst takes a transition metal nickel monatomic as an active component, the loading capacity of the active component is 2-5wt.%, a nitrogen-doped carbon material is taken as a carrier, and the microstructure of the carrier is a rhombic dodecahedron with the particle size of 100-200nm. The difunctional electrocatalyst used in the invention has excellent double functions of carbon dioxide electroreduction and sulfur dioxide electrooxidation activity, is applied to the constructed novel carbon dioxide electrolysis system, has lower electric energy consumption and operation cost compared with the traditional electrolysis system, and has huge application potential.

The application discloses a bifunctional In-doped Ni2Mo3N@Mo2C binary heterojunction catalyst and a preparation method and application thereof. A dimethyl imidazole solution is slowly added into a Mo salt solution to obtain a suspension liquid containing a Mo metal organic framework Mo-MOF; the suspension liquid is left to stand, and a precipitate is centrifuged and washed, and vacuum dried to obtain the Mo-MOF containing the Mo metal organic framework; a Ni salt, an In salt and the Mo-MOF are added into an anhydrous ethanol solution to perform ion exchange, and the precursor is vacuum dried to obtain the bifunctional In-doped Ni2Mo3N@Mo2C binary heterojunction catalyst. The catalyst material has excellent basic oxygen evolution and urea oxidation activity, and has a good application prospect in electrocatalytic decomposition of water, urea-assisted electrolysis of water and treatment of sewage containing urea.

The invention discloses an oxidoreductase mutant and application thereof, and belongs to the field of enzyme engineering. The invention provides a recombinant oxidoreductase HbKR mutant which is used for catalytically producing (R)-decalactone. The oxidoreductase HbKR mutant disclosed by the invention realizes soluble expression in Escherichia coli BL21 (DE3), and the oxidation activity of the oxidoreductase HbKR mutant is improved by 4.61 times compared with that of a parent enzyme. An oxidoreductase HbKR mutant and lactone hydrolase Rpa3624 derived from Rhodopseudomonas palustris are combined for use, reaction is performed for 0.5 h under the conditions that the temperature is 35 DEG C and the pH value is 10.5, compared with a wild type, the yield of (R)-delta-decalactone is increased to 48.2% from 42.3%, and the stereoselectivity is increased to 98.7% from 94.2%.

The invention provides a preparation method of a Zn-Cr spinel oxide catalyst and application of the Zn-Cr spinel oxide catalyst in CO2-assisted ethane dehydrogenation, and relates to the technical field of composite catalysts. Wherein the Zn-Cr spinel oxide catalyst is prepared by firstly preparing a Zn1Crx oxide carrier by adopting a coprecipitation method and then loading Cr on the surface of the Zn1Crx oxide carrier by adopting an impregnation method, and in the process, strong metal-carrier interaction can be formed between the loading of Cr on the surface of the carrier and the Zn1Crx oxide carrier, so that the oxygen vacancy concentration on the surface of the catalyst is regulated and controlled and the desorption of ethylene is promoted; according to the present invention, the Zn1Crx carrier is used as the catalyst to inhibit the excessive oxidation of the Zn1Crx carrier so as to significantly improve the selectivity of ethylene, and the metal Cr forms the compact covering layer on the surface of the Zn1Crx carrier so as to reduce the number of the strong oxidation active sites, synergistically promote the rapid desorption of ethylene, and inhibit the occurrence of the side reactions such as dry reforming and hydrogenolysis.

The invention discloses a method for preparing a solvent soluble component through lignite ozone oxidation depolymerization, and belongs to the technical field of lignite deep processing. The method comprises the following steps: weighing lignite, adding the lignite into acetic acid or water, introducing a mixed gas of ozone and oxygen into a system, and carrying out a stirring reaction at room temperature; and after the reaction is finished, centrifugally filtering the mixture, and collecting a liquid sample. According to the method, the solvent-soluble component is prepared through depolymerization of ozone oxidation lignite, the ozone production cost is low, the oxidation activity is high, accurate regulation and control of the oxidation depolymerization depth of lignite macromolecules can be achieved under the mild condition, the lignite macromolecules are promoted to be directionally converted into the solvent-soluble component under the mild condition, the yield of solvent-soluble substances is high, and the method is suitable for industrial production. And a new thought is provided for clean and efficient utilization of coal.

The invention belongs to the field of catalytic materials, and particularly discloses a double noble metal supported molecular sieve catalyst for catalyzing oxygen to oxidize methane to prepare acetic acid. The preparation method comprises the following steps: mixing a chloroauric acid solution and another noble metal chloride solution as precursors with a molecular sieve, adjusting a certain pH value, stirring and aging at a proper water bath temperature for a certain time, and then filtering, drying and calcining to obtain the catalyst. According to the catalyst, a molecular sieve is used as a carrier, gold is used as an oxidation active center, carbon-carbon coupling is achieved with another precious metal, high-selectivity acetic acid preparation through methane pure oxygen direct oxidation can be achieved under the mild condition of 120-240 DEG C, and the selectivity reaches up to 97.2%. The catalyst preparation method adopted by the invention is simple in process, green and pollution-free, high in noble metal loading efficiency, low in price and easy for expanded production, and provides a thought for developing and preparing a high-efficiency catalyst for direct selective oxidation of methane under mild conditions.

The invention relates to a preparation method and application of an adsorption-photocatalysis bifunctional MILs material with oxygen vacancy defect and optical excitation high-valence iron oxidation activity, and belongs to the technical field of water pollution treatment materials. The novel adsorption-photocatalysis dual-function MILs material is prepared aiming at organic pollutants existing in a trace amount in a water environment and the defects that an existing water treatment method is low in treatment efficiency, high in cost and the like. According to the bifunctional material, MIL-101 (Fe) serves as a precursor, metal elements are introduced through one-step doping, especially Ti element (named Ti / Fe-MIL-101) is prepared, oxygen vacancy defects are constructed, photon-generated carrier separation is promoted, and Fe (IV) is generated to participate in oxidative degradation of organic pollutants. The apparent degradation rate of the Ti / Fe-MIL-101 to diclofenac sodium is 0.0287 min <-1 >, and compared with MIL-101 (Fe), the apparent degradation rate of the Ti / Fe-MIL-101 is respectively improved by 7.56 times, 2.43 times, 2.79 times and 5.52 times; the adsorption capacity of the material to diclofenac sodium is 2.580 mmol / g, and compared with MIL-101 (Fe), the adsorption capacity of the material to the diclofenac sodium is increased by 1.30 times, 1.20 times, 1.17 times and 1.37 times respectively, and the adsorption capacity of the material to the diclofenac sodium is increased by 1.20 times, 1.17 times and 1.37 times respectively.

The present invention relates to a composition, a kit and a detection method for detecting hydrogen peroxide on the basis of self-biotinylation according to the peroxidation activity of a guanine quadruplex, and, more specifically, to a composition, a kit and a detection method for detecting hydrogen peroxide, the composition comprising: i) a guanine quadruplex-hemin complex (G-quadruplex-hemin complex); ii) biotinyl tyramide; and iii) a probe capable of binding to the guanine quadruplex.

This invention provides a composite catalyst, its preparation method, and its application, as well as a method for the catalytic oxidation of alcohols to aldehydes, belonging to the field of organic synthesis technology. In the composite catalyst provided by this invention, elemental chromium improves the dispersibility of elemental silver on modified γ-Al₂O₃, thereby enhancing the oxidation activity of the composite catalyst for ethanol, reducing side reactions (further oxidation of aldehydes to acids or decomposition) during the catalytic oxidation of alcohols to aldehydes, and improving the selectivity, yield, and purity of aldehydes. The modified γ-Al₂O₃ has a more developed pore structure than uncalcined γ-Al₂O₃, and when used as a support, it improves the mechanical strength of the composite catalyst. Moreover, the composite catalyst provided by this invention reduces the reaction temperature and energy consumption for the catalytic oxidation of alcohols to aldehydes without affecting the alcohol conversion rate and aldehyde selectivity, thus reducing the cost of aldehyde preparation and making it more suitable for industrial use in the catalytic oxidation of alcohols to aldehydes.

The present invention relates to novel enzyme nanoparticles capable of converting methane into methanol, in which key active sites of methane-oxidizing bacteria are fused with each other and expressed on a protein that can be self-assembled in cells to form nanoparticles, and specifically to enzyme nanoparticles including a protein having methane monooxygenase (MMO) activity and active sites of the methane oxidase, a method for production thereof, a recombinant microorganism into which a nucleic acid encoding the protein and the active site of the methane oxidase is introduced, and immobilized enzyme nanoparticles including the enzyme nanoparticles loaded on a carrier.

The present application relates to a kind of anti-poisoning catalyst for blast furnace gas organic sulfur hydrolysis and its preparation method.Each component is as follows in percentage by weight: active component K2CO3 4-12%;Active component Cs2CO3 2-5%;Catalyst aid MoO3 3-8%;Catalyst aid La2O3 0.5-2%;Molding aid SiO2 1-5%;And composite metal oxide carrier Al2O3-TiO2 68-89.5%, the pore size of the composite metal oxide carrier Al2O3-TiO2 is three channel distribution.First, composite metal oxide carrier is prepared, and after being formed with silicon dioxide, active component and catalyst aid are impregnated to prepare catalyst.The catalyst prepared by the present application has excellent catalytic hydrolysis activity for organic sulfur in blast furnace gas, and has anti-sulfur, anti-chlorine and anti-oxygen poisoning performance and has persistent catalytic oxidation activity.

The present application relates to the technical field of non-noble metal catalysts, and provides a sulfur-doped cobalt-based material with a core-shell porous structure, which has Co nanoparticles as an inner core, and a porous carbon layer containing Co9S8 coated on the surface of the Co nanoparticles. The present application significantly enhances the catalytic capacity of the material by regulating the micro-morphology and surface active site composition and structure of the material through sulfur doping. On the one hand, the metal sulfide obtained by S doping improves the electrical conductivity of the catalyst, and on the other hand, the S element can regulate the microstructure and morphology of the material due to its strong reducing effect, so that S doping is beneficial to promoting the exposure of active sites and the diffusion of target molecule, thereby significantly enhancing the oxygen molecule activation efficiency and improving the benzyl alcohol oxidation activity and selectivity.

The invention discloses a label for time indication as well as a preparation method and a design method of the label. The label comprises a label main body, an oxidation color-changing film arranged on the surface of one side of the label main body, and an oxygen permeation regulation and control layer wrapping the label main body and the oxidation color-changing film. According to the label for time indication, the nano-metal material has high specific surface area and high oxidation activity, and the oxidation rate of the nano-metal material is not restricted by the passivation layer. Meanwhile, after the nano metal particles are coated with the high-molecular polymer film, a stable oxygen permeation rate of the film is controlled, a stable oxygen environment is provided for the label, the oxidation discoloration process of the label can be accurately controlled, and the label is in approximately linear positive correlation with the air contact time. The preparation method is simple and convenient, and the indication period of the label is adjusted by adjusting the activity of the oxidation discoloration rate regulating agent and the oxygen permeability of the oxygen permeability regulating layer.