3014results about "Carbonyl compound preparation" patented technology

The invention discloses a method for chemically synthesizing berberine hydrochloride. The method comprises the following steps: firstly, synthesizing a methyl substance; synthesizing a condensation compound; then, berberine hydrochloride is synthesized; the synthesis method has the advantages of cheap and easily available raw materials, less generated three wastes, environmental protection, no use of a heavy metal catalyst, no drug safety risk caused by excessive heavy metals in the finished product, no high-temperature and high-pressure reaction, mild reaction conditions, simple required equipment, convenient operation and good controllability, and is suitable for large-scale industrial production; the purity of berberine hydrochloride produced through the method can reach 99.8% or above, the single impurity content is smaller than 0.1%, and the medicine safety and effectiveness are greatly guaranteed.

The invention discloses a method for synthesizing deuterated olefin under catalysis of a palladium membrane by taking D2O as a deuterium source, and belongs to the technical field of synthesis of deuterated olefin building blocks. According to the method, a three-chamber electrolytic tank separated by a palladium membrane and an ion exchange membrane is used as a reactor, the palladium membrane is used as a working electrode, an electrolyte deuterium aqueous solution is used as an electrolyte, deuterium water is electrolyzed through a constant-potential electrolysis method, and formed active deuterium is transmitted to one side of an organic reaction taking absolute ethyl alcohol or cyclohexane as an organic solvent; and catalyzing an alkyne compound by using a palladium membrane modified by sodium thiophenol to perform reduction deuterization so as to synthesize a deuterated olefin compound with high selectivity, and further synthesizing a corresponding deuterated drug. The invention provides a green, efficient, high-universality and low-cost amplification synthesis method for synthesizing a deuterated olefin building block containing a functional group easy to reduce and hydrolyze, and the method has a wide application prospect.

The present disclosure relates to methods and intermediates useful for preparing a compound of formula I:or a co-crystal, solvate, salt or combination thereof.

The invention discloses an immobilized organic base catalyst and a preparation method and application thereof, the immobilized organic base catalyst comprises functionalized activated carbon, the functionalized activated carbon has a Bronsted base site comprising an organic Bronsted base molecular structure, the organic Bronsted alkali molecular structure is connected to the surface of the functionalized activated carbon through a covalent bond. The immobilized organic base catalyst is a heterogeneous active carbon-based immobilized organic # imgabs0 # base catalyst, and has the advantages of low preparation cost, high reaction activity, good stability and the like.

The invention discloses a method for preparing formaldehyde through photocatalytic methane selective oxidation, and relates to the technical field of formaldehyde preparation. The method comprises the following steps: ultrasonically dispersing a titanium dioxide supported copper monatomic catalyst into water, adding into a reaction kettle, sequentially introducing oxygen and methane into the reaction kettle until the required pressure is reached, and stirring and reacting for a period of time under an illumination condition to obtain formaldehyde and other oxidation products, in the reaction process, the dosage of the titanium dioxide supported copper monatomic catalyst is 0.1-10 mg, and the dosage of the water solvent is 0-100 mL; the catalyst is a titanium dioxide supported copper monatomic catalyst. According to the method, methane is used as a raw material, oxygen is used as an oxidizing agent, methane is selectively converted into formaldehyde under the combined action of illumination and the titanium dioxide supported copper monatomic catalyst, the obtained formaldehyde has high generation rate and selectivity, the reaction process is green and economical, and the method has wide application prospects.

The present application provides a device and method for preparing methyl isoamyl ketone. In the method, acetone and isobutyraldehyde are reacted under the catalysis of a condensation catalyst and a hydrogenation catalyst in the presence of hydrogen to obtain the methyl isoamyl ketone, wherein the condensation catalyst comprises an organic base; and the molar ratio of the condensation catalyst to the isobutyraldehyde is (0.02-0.15):1. The MIAK obtained by the method has at least one of the advantages of high conversion rate, simple process flow, low production cost, easy separation of side reaction products, and high product purity.

The invention provides a preparation method of a triazine / heptazine homojunction structure carbon-doped carbon nitride photocatalyst, which comprises the following specific steps: (1) placing mixed powder of melamine and 2, 4, 6-triaminopyrimidine in air, heating to 300-500 DEG C, and calcining for 2-6 hours to form a mixture of carbon-doped melamine and oligomer thereof; (2) placing the mixture obtained in the step (1) in water at 60-70 DEG C, performing ultrasonic dispersion, then slowly cooling to room temperature, oscillating for 12-36 hours, removing moisture through rotary evaporation, and further drying to obtain a solid supramolecular precursor; and (3) fully mixing the solid supramolecular precursor obtained in the step (2) with molten salt, calcining at 500-600 DEG C for 2-6 hours, cooling, fully washing with deionized water, removing mixed salt, separating solid residues, and drying to obtain the triazine / heptazine homojunction structure carbon-doped carbon nitride photocatalyst THCNx-t. The prepared carbon-doped carbon nitride photocatalyst is uniform in homojunction distribution, and has the characteristics of excellent photochemical properties, high photon-generated carrier separation efficiency and excellent photocatalytic benzyl alcohol selective oxidation performance.

To provide a fluorinating agent that can be produced using a simple method, and a fluorination method that uses a fluorinating agent that can be produced using a simple method.SOLUTION: The present disclosure provides a fluorinating agent that comprises a fluorine-containing compound and fluoride ions.SELECTED DRAWING: None

The invention discloses a catalyst for preparing acrolein and acrylic acid through selective oxidation of propylene, a preparation method of the catalyst and a preparation method of acrolein and acrylic acid. The general formula of the catalyst is MoBiaFebXcYdZePfOj, X is selected from at least one of Mg, Co, Ni, Ca, Cu, Zn and Mn, Y is selected from at least one of Nb, Sb and W, and Z is selected from at least one of K, Rb, Na, Li and Cs. The catalyst is used for preparing acrolein and acrylic acid through olefin oxidation, especially propylene oxidation, has the advantage of high total yield of acrolein and acrylic acid, and is good in structural stability.

The invention discloses microchannel reaction equipment and a method for continuously synthesizing beta-ionone. The micro-channel reaction equipment comprises a low-temperature pipe section and a high-temperature pipe section communicated with the tail end of the low-temperature pipe section; the low-temperature pipe section and the high-temperature pipe section respectively comprise two wavy reaction pipes which are arranged in a staggered manner; the two reaction tubes of the low-temperature tube section accord with the trend of a cosine function curve along the axial extension direction, and the two reaction tubes of the high-temperature tube section accord with the trend of a sine function curve along the axial extension direction. By adopting the micro-channel reaction equipment to continuously react and synthesize beta-ionone, the generation of other isomers and tar substances can be controlled, so that the reaction is mainly carried out towards the generation direction of the beta-ionone, and the subsequent separation operation does not need rectification operation with a high theoretical plate number; therefore, a high-purity beta-ionone product can be obtained.

The invention discloses a supported iron-molybdenum catalyst for formaldehyde production and a preparation method and application thereof, and belongs to the field of catalysts.The catalyst comprises a core-shell structure, the core of the catalyst is a carrier, molybdenum trioxide is supported on the carrier, and the shell of the catalyst is iron molybdate. The carrier is selected from at least one of silicon dioxide, aluminum oxide, titanium oxide, magnesium oxide, magnesium silicate, a molecular sieve, white carbon black and hydroxyapatite; the preparation method comprises the following steps: firstly, loading molybdenum trioxide on a carrier, then dispersing the carrier in deionized water, dropwise adding a molybdenum source solution and an iron source solution in a parallel flow manner under stirring to perform deposition loading of iron molybdate, and performing aging, drying, forming and calcining to obtain the catalyst. The catalyst is used for preparing formaldehyde by oxidizing methanol, dimethyl ether and methylal; according to the catalyst disclosed by the invention, the raw material cost and the pollutant treatment capacity are obviously reduced due to the reduction of the dosage of molybdenum and iron components, and the catalyst has relatively good activity and stability.

The invention relates to a spherical chiral covalent organic framework and a preparation method and application thereof.The spherical chiral covalent organic framework is a spherical chiral L-DTP-TAPB COF material containing a proline fragment, and the L-DTP-TAPB COF material has high crystallinity and spherical morphology, contains rich tetrahydropyrrole chiral catalytic sites, and has the advantages of being high in catalytic activity and high in catalytic activity. The catalyst can be applied to asymmetric aldol reaction and shows excellent catalytic activity. In catalysis of a reaction of p-nitrobenzaldehyde and cyclohexanone, the reaction yield is up to 96%, the ee value can reach 87%, and the catalytic performance of the chiral COFs and chiral metal organic framework catalysts is higher than that of most reported chiral COFs and chiral metal organic framework catalysts. And meanwhile, excellent recycling performance is also shown.

The invention relates to the technical field of organic synthesis, and provides a method for efficiently preparing 1, 3-cyclohexanedione through selective hydrogenation, which comprises the following steps: preparing hexagonal mesoporous silicon oxide by taking tetraethoxysilane as a silicon source and dodecylamine as a structure-directing agent, compounding the hexagonal mesoporous silicon oxide with titanium oxide to obtain a carrier, and taking palladium as a catalytic active component to prepare a catalyst I; preparing a copper-based coordination polymer by taking copper chloride dihydrate and phenylacetylene as raw materials; preparing a catalyst II by taking nickel as a catalytic active component; the method comprises the following steps: reacting resorcinol with hydrogen under the combined action of alkali, water, a catalyst I and a catalyst II, and then acidizing and recrystallizing to obtain the target product 1, 3-cyclohexanedione. According to the method, resorcinol is taken as a raw material, the self-made catalyst I and the self-made catalyst II are adopted for concerted catalytic hydrogenation, 1, 3-cyclohexanone with relatively high purity is prepared, and the catalysts are high in catalytic activity, easy to separate and still have very good catalytic performance after being recycled for multiple times.

The invention relates to a method for preparing cyclohexanone by conversion of acetone and 1, 3-propylene glycol, and belongs to the technical field of chemical engineering. The method comprises the following steps: catalyzing a dialkylation reaction of acetone and 1, 3-propylene glycol by virtue of a supported nickel or palladium catalyst and a potassium phosphate cocatalyst, and removing water from acetone and 1, 3-propylene glycol which are equal in molar weight, so as to obtain cyclohexanone. The method contributes to the production of bulk chemicals and fine chemicals by a fermentation method, and makes a contribution to the strategic goal of low-carbon development.

The invention provides a preparation method of a shape-controllable iron-molybdenum formaldehyde catalyst, and belongs to the technical field of catalyst preparation. The preparation method of the catalyst comprises the following steps: firstly, respectively mixing ammonium heptamolybdate tetrahydrate, ferric nitrate nonahydrate and a complexing agent, and dissolving in water to prepare a molybdenum-containing solution and an iron-containing solution; then mixing the molybdenum-containing solution and the iron-containing solution, adjusting the pH value, carrying out vacuum rotary evaporation to form sol, finally drying the sol to form xerogel, and roasting the xerogel to obtain a catalyst finished product. The coordination environment of Mo and Fe in the precursor solution is regulated and controlled through the complexing agent, uneven distribution of components is prevented, the uniform precursor solution is formed, the morphology and particle size of the catalyst are influenced by adjusting the pH of the solution and changing the precipitation rate of the precursor and the growth process of particles, and the catalyst with different morphologies and excellent comprehensive performance is prepared.

The invention discloses a preparation method of 6-methyl-5-octylene-2-ketone, and belongs to the technical field of organic synthesis. According to the method, 5-chloro-2-pentanone is taken as a starting raw material, carbonyl protection is carried out with trimethyl orthoformate under the catalysis of acid, then a Grignard reagent is prepared, condensation dehydration is carried out on the Grignard reagent and 2-butanone, deprotection is carried out under the acidic condition, and 6-methyl-5-octylene-2-ketone is prepared with high yield, the raw materials are easy to obtain and low in price, and the reaction can be catalyzed by using a conventional catalyst.

The invention provides a preparation method of rotaxane mechanical interlocking molecules. According to the preparation method, under the condition of not adding a catalyst, dibenzene-24-crown-8, benzene-21-crown-7, an isocyanate derivative and a rod-shaped compound are subjected to a reaction by adopting a one-pot method to obtain the rotaxane mechanical interlocking molecule. The preparation method not only can reach 100% of atom economy and meet the requirements of green chemistry, but also can reach the yield of 65% or above, and realizes efficient preparation of rotaxane mechanical interlocking molecules.

The invention provides a catalyst for preparing hydroxyaldehyde through olefine aldehyde hydration and a preparation method and application thereof.The catalyst comprises a styrene acid resin matrix and metal ions bonded to the styrene acid resin matrix, the metal ions are combined with the styrene acid resin matrix through acid groups carried by the styrene acid resin matrix, the content of the metal ions in the catalyst is 10-10000 ppm, the acid equivalent is 3.5-5.4 mmol / g, and the content of the metal ions in the catalyst is 10-10000 ppm. The metal ions are selected from one or more of alkali metal ions, alkaline earth metal ions, transition metal ions and amphoteric metal ions. By utilizing the catalyst for preparing the hydroxyaldehyde through the hydration of the olefine aldehyde, the acidity of a reaction solution for preparing the hydroxyaldehyde through the hydration of the olefine aldehyde can be controlled, side reactions in a system can be reduced, the selectivity of the hydration reaction is improved, the service life of the catalyst for the subsequent hydrogenation reaction is prolonged, and the product quality can also be improved. The method can avoid the problem that the subsequent separation difficulty is increased due to the fact that organic acid is additionally added to adjust acidity and reduce the concentration of reaction raw materials to increase yield.

The invention discloses a method for synthesizing phenolic compounds by catalyzing hydroxylation reaction of aromatic compounds by iron, which comprises the following step: in a solvent, catalyzing and oxidizing aromatic compounds to synthesize phenolic compounds by taking iron as a catalyst and amino acid or derivatives thereof as ligands under the action of an oxidizing agent and a reducing agent. According to the method, the phenolic compound is synthesized by carrying out hydroxylation on the C-H bond of the catalytic oxidation aromatic compound. The method has the advantages that the catalyst is wide in source and low in cost; the oxidant is wide in source, safe and environment-friendly; the compatibility of substrate functional groups is good, and the reaction selectivity is good; complex small molecules can be well converted into hydroxylated products, and the like. According to the method disclosed by the invention, under optimized reaction conditions, the yield of the separated target product can reach 95%.

The invention relates to the field of organic synthesis, in particular to a synthetic method of 1-(2, 6, 6-trimethyl-1, 3-cyclohexadiene-1-yl) ethanone, and particularly relates to a synthetic method of 1-(2, 6, 6-trimethyl-1, 3-cyclohexadiene-1-yl) ethanone by taking 4-acetyl-3, 5, 5-trimethylcyclohexene as a raw material and carrying out bromination and elimination steps to synthesize the 1-(2, 6, 6-trimethyl-1, 3-cyclohexadiene-1-yl) ethanone. The method has the advantages of easily available raw materials and high reaction yield, and can be industrially implemented on a large scale.

A process for the production of methyl methacrylate is disclosed, the method comprising: a) producing methacrolein from propionaldehyde and formaldehyde; and b) reacting the methacrolein in an oxidative esterification reaction to obtain methyl methacrylate. Reacting the methacrolein in an oxidative esterification reaction comprises introducing a reaction mixture comprising the methacrolein, methanol, and an oxygen-containing gas to a reactor system comprising a heterogeneous noble metal-containing catalyst. A liquid phase stream exiting the reactor system contains at least 30 wt % methanol based on the total weight of the liquid phase stream. The liquid phase stream exiting the reactor system contains less than 30 wt % methacrolein based on the total weight of the liquid phase stream. The liquid phase stream exiting the reactor system comprises greater than 0.1 ppm and less than 5000 ppm methyl isobutyrate. A gas phase stream exiting the reactor system comprises between 1 mol % and 7.5 mol % oxygen based on the total amount of the gas phase stream.

The invention discloses a low-temperature waste heat recovery method and system of a phenol-acetone device and application of the low-temperature waste heat recovery method and system. The method comprises the following steps: generating first steam and first condensate by a low-pressure flash tank of a phenol-acetone device, and carrying out primary heat exchange on the first condensate and an oxidation feed to obtain the first condensate after heat exchange; changing the first condensate after heat exchange to normal pressure, mixing the first condensate with the second condensate to obtain third condensate, and performing secondary heat exchange on the third condensate and the gas-phase material at the top of the benzene tower to obtain third condensate after heat exchange; the third condensate obtained after heat exchange is subjected to pressure reduction and then subjected to flash evaporation treatment, low-temperature negative-pressure steam and condensate are generated, and part of the condensate serves as second condensate to be used; heating and pressurizing the low-temperature negative-pressure steam, and then carrying out steam-water separation to obtain second steam; the first steam and the second steam are optionally recycled. Waste heat of condensed water in the low-pressure flash tank is fully utilized, integrated heat exchange and optimized utilization are carried out on the waste heat and materials of the device, and the energy-saving and consumption-reducing effects are achieved.

The invention belongs to the technical field of catalytic degradation, and particularly relates to a bismuth cluster / CTF composite photocatalyst and a preparation method and application thereof. The bismuth cluster and CTF are compounded through a hydrothermal method, photocatalytic cracking of lignin can be achieved, efficient separation of photo-induced electrons and holes of the photocatalyst can be achieved, fine adjustment of the electron structure of the photocatalyst is achieved by adjusting the addition amount of the bismuth cluster precursor, generation of h < + > and. O < 2-> in the photocatalytic process is improved, and the photocatalytic performance of the photocatalyst is improved. Therefore, the yield of the aromatic monomer prepared by cracking the lignin is improved, the cracking conversion rate can reach 78.5%, the yield of benzoic acid can reach 65.2%, the yield of benzaldehyde can reach 81.4%, the yield of phenyl formate can reach 52.6%, and the method is green, clean and safe.

The invention relates to the technical field of preparation of catalytic materials, in particular to a preparation method of a modified BN two-dimensional catalytic material and application of the modified BN two-dimensional catalytic material in methane conversion. S2, preparing a boron nitride material; s3, modification of a boron nitride material; and S4, post-processing. The modeling modification liquid prepared from the oxygen stability enhancing liquid and the boron nitride material form a heterojunction structure, separation of photo-induced electron-hole pairs is remarkably promoted, solar driven catalytic reaction kinetics is improved, oxygen doping sites on the surface of the boron nitride material can be dynamically adjusted, oxygen elements are prevented from being lost in the reaction, and the service life of the boron nitride material is prolonged. The long-acting stability of the catalytic material is ensured. According to the method, the efficiency of solar catalytic methane conversion is improved, a large amount of carbon dioxide is generated, high-yield generation of high-value chemicals such as methanol or formaldehyde under the mild condition is achieved, and a new way is provided for green methane conversion.

This method for producing a deuterium-labeled compound is characterized by comprising: supplying a proton supply source and heavy water to the anode side of a membrane electrode assembly including an electrode and a proton conductive membrane; supplying a compound to be deuterated to the cathode side of the membrane electrode assembly; and energizing the membrane electrode assembly to deuterate the compound on the cathode side.

The invention belongs to the technical field of photocatalytic oxidation of gaseous alkanes, and particularly relates to a method and system for photocatalytic oxidation of gaseous alkanes, and the method comprises the following steps: under illumination, enabling a photocatalyst, bubbles containing gaseous alkanes and chlorine-containing active substances to react at an interface of a two-phase system containing an organic phase and a water phase to generate an oxidation product, the oxidation product comprises one or more of acid, alcohol and aldehyde, and the organic phase can dissolve the chlorine-containing active substance. The method provided by the invention is beneficial to improving the generation rate of oxidation products and the apparent light quantum efficiency of photocatalytic reaction.

The invention discloses a Mo-Bi-based catalyst and a preparation method and application thereof.The catalyst comprises active components, the active components comprise spherical particles and molybdenum oxide nanorods attached to the surfaces of the spherical particles, and the spherical particles contain molybdenum and / or molybdenum oxide and bismuth and / or bismuth oxide. When the catalyst is applied to propylene oxidation synthesis of acrolein, the catalyst has the technical effect of high acrolein selectivity.

The invention belongs to the technical field of chiral boron compound synthesis, and particularly relates to an MOF-Cu (II) / CMC composite material and a preparation method and application thereof. The preparation method of the MOF-Cu (II) / CMC composite material comprises the following steps: dropwise adding an aqueous solution of sodium carboxymethyl cellulose into an aqueous solution of bivalent copper salt, carrying out solid-liquid separation, mixing obtained composite microspheres and an organic solution of trimesic acid, heating, and carrying out solid-liquid separation to obtain the MOF-Cu (II) / CMC composite material. The composite material is applied to an asymmetric chiral boron addition reaction, the reaction is carried out at room temperature, the conditions are mild, the use range of a substrate is wide, and the yield and enantioselectivity are high. According to the method, the chiral organic boride can be synthesized in a simple component solvent, an efficient new method is provided for preparation of drug molecules and active intermediates, the substrate range of preparation of the chiral organic boride is widened, and the method has important theoretical and practical significance.

The invention provides structures and synthesis of a class of piezoelectric monomers and COFs with fluorine-substituted side chains tethered on the peripheral position of an aromatic moiety (thus different functional side chains). The multi-fluoro groups on the mentioned piezoelectric COFs provide abundant piezoelectric active sites, which enable the application as the active layer for PENGs. The exemplary embodiments also provide a process for the fabrication of a piezoelectric COF and a process for the fabrication of the piezoelectric nanogenerator utilizing mentioned piezoelectric COF.

This invention belongs to the field of high-value utilization technology of biomass resources, and discloses a method for catalyzing the depolymerization of lignin into phenolic compounds using a RuNiZn / Nb2O5 catalyst. The method includes: uniformly mixing the RuNiZn / Nb2O5 catalyst, lignin-containing biomass feedstock, and water; stirring under hydrogen atmosphere to carry out the depolymerization reaction; after the reaction, cooling to room temperature and performing solid-liquid separation; evaporating the solvent to obtain the hydrogenated depolymerization product containing monophenols. In this invention, the RuNiZn / Nb2O5 catalyst employs a technique of replacing precious metals with various non-precious metals, which improves the catalyst's reactivity and reduces the amount of precious metals used. This increases the yield of lignin depolymerization products, provides milder depolymerization reaction conditions, and ultimately significantly reduces the catalyst preparation cost and the energy cost of the lignin depolymerization process.