23379 results about "Synthesis methods" patented technology

This invention discloses methods for preparing compositions of cyclodextrin polymers for carrying drugs and other active agents. Methods are also disclosed for preparing cyclodextrin polymer carriers that release drugs under controlled conditions. The invention also discloses methods for preparing compositions of cyclodextrin polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action. The advantages of the water soluble (or colloidal) cyclodextrin polymer carrier are: (1) Drugs can be used that are designed for efficacy without conjugation requirements. (2) It will allow the use of drugs designed solely for efficacy without regard for solubility. (3) Unmodified drugs can be delivered as macromolecules and released within the cell. (4) Drugs can be targeted by coupling the carrier to biorecognition molecules. (5) Synthesis methods are independent of the drug to facilitate multiple drug therapies.

A self-immolative dendrimer capable of releasing all of its tail units upon a single cleavage event, methods of synthesizing same and uses thereof are disclosed.

The invention relates to a novel spirodiclofen compound and a preparation method and application thereof. The structure of the novel spirodiclofen compound is shown in a general formula I. The synthesis method of the novel spirodiclofen compound comprises the steps of: in the presence of an acid binding agent, in an aprotic solvent, reacting a compound with a structure formula II with chloro-carbonic ester with a structure formula shown in the description at room temperature, and separating and purifying a product to prepare the novel spirodiclofen compound. The novel spirodiclofen compound can be used for killing pests or mites.

The present invention provides new compositions containing colloidal nanocrystals with high photoluminescence quantum yields, new synthetic methods for the preparation of highly luminescent colloidal nanocrystals, as well as methods to control the photoluminescent properties of colloidal nanocrystals. The new synthetic methods disclosed herein allow photoemission brightness (quantum yield) to be correlated with certain adjustable nanocrystal growth parameters associated with a given synthetic scheme.

Methods of improving the kinetics of bimolecular interactions where reactants are present in low concentrations are provided. Methods of pre-amplifying one or more oligonucleotides using high concentration universal primers are provided. Methods of improving the error rate in oligonucleotide and/or polynucleotide syntheses are also provided. Methods for sequence optimization and oligonucleotides design are further provided.

The present invention relates to a synthesis method of carbon nanotubes, and more particularly to an apparatus for a mass synthesis of carbon nanotubes in gas phase using an atmospheric-pressure microwave plasma torch. The method and apparatus is described for the continuous production of carbon nanotubes by making use of a microwave plasma torch operated at a frequency of 2.45 GHz, by introducing a transition metal catalyst precursor and a carbon containing gas into the microwave plasma torch to produce atomized catalyst metal and to decompose the carbon containing gas, by passing the resulting gaseous mixtures through a furnace, and by quenching rapidly and collecting the products so formed at the exit of the furnace. The resultant products are the carbon nanotubes.

The invention discloses a remote sensing image classification method based on multi-feature fusion, which includes the following steps: A, respectively extracting visual word bag features, color histogram features and textural features of training set remote sensing images; B, respectively using the visual word bag features, the color histogram features and the textural features of the training remote sensing images to perform support vector machine training to obtain three different support vector machine classifiers; and C, respectively extracting visual word bag features, color histogram features and textural features of unknown test samples, using corresponding support vector machine classifiers obtained in the step B to perform category forecasting to obtain three groups of category forecasting results, and synthesizing the three groups of category forecasting results in a weighting synthesis method to obtain the final classification result. The remote sensing image classification method based on multi-feature fusion further adopts an improved word bag model to perform visual word bag feature extracting. Compared with the prior art, the remote sensing image classification method based on multi-feature fusion can obtain more accurate classification result.

The invention provides an automatic synthesis method for a facial image. A user inputs two facial source images, a target image and semantic information of an area to be edited; a model matching module utilizes an active appearance model to automatically search an image and provide facial shape information and facial texture information of the facial image; then, the shapes of the two facial images are aligned by using the characteristics of the model, and the shapes of the source images in the edited area are aligned to a corresponding area in the target image by virtue of the deformation of a sheet sample band; a characteristic synthesis module is used for characteristic synthesis for the shape information and the texture information of the aligned source images and the target image, so as to generate a synthetic image automatically; an occlusion processing module is used for occlusion processing the synthetic image, and the occlusion areas of the source images are divided, matched and seamlessly integrated into the target image. Compared with the traditional facial synthesis, the invention integrates the characteristic areas of the two images and solves the problem of image distortion caused by partial face occlusion in the target image.

The invention provides a medical image synthesis method based on double generative adversarial networks. The method comprises the main content of performing data management, generating the generativeadversarial networks, training a U-NET, establishing assessment indexes and obtaining processed pictures, wherein first, a DRIVE database is used to manage a first-stage GAN, then the first-stage GANgenerates a partitioning mask representing variable geometry of a dataset, a second-stage GAN converts the mask produced at the first stage into an image with a sense of reality, an generator minimizes a loss function of the true data in classification through a descriminator, then the U-NET is trained to assess the reliability of synthetic data, and finally the assessment indexes are establishedto measure a generated model. According to the method, by use of a pair of generative adversarial networks to create a new image generation path, the problem that the synthetic image contains a fake shadow and noise is solved, the stability and the sense of reality of the image are improved, and meanwhile image details are clearer.

The invention discloses a quick and efficient synthesis method for silver nanowires. The method comprises the following steps of: 1) introducing inert gas into a reactor, adding 2 volume parts of glycol into the reactor, and stirring, heating, condensing and refluxing the glycol; quickly adding 1 volume part of glycol solution of silver nitrate at molar concentration of between 0.1 and 0.5m into the reactor; slowly dropwise adding 1 to 2 volume parts of PVP at molar concentration of between 0.15 and 0.75m and 4 to 32 mu m of glycol solution of MnCl2 at the same time; and reacting and cooling the mixture to the room temperature to obtain reaction mother liquor of the silver nanowires; and 2) transferring the reaction mother liquor of the silver nanowires into a centrifugal tube; adding acetone into the centrifugal tube and performing centrifugal separation to remove supernatant and retain precipitate; adding de-ionized water or ethanol into the centrifugal tube and performing centrifugal separation to remove the supernatant and retain precipitate, and repeating the operation for 1 to 3 times; and extracting and dispersing the precipitate with ethanol to obtain the silver nanowires. The method shortens the reaction time and also has high selectivity for the synthesis of the silver nanowires under conditions of high concentration.

The invention discloses a preparation method for increasing raman activity of a basement in a surface of a large area of a micro-nano tree structure array, which firstly prepares a large area of a silicon micron cylinder array; a nanometer assembling technology is used for producing a nanometer stick in the silicon micron cylinder array. then a three-dimensional ordered periodic micro-nano structure array is obtained; and various appearance of metal nano-particles are embedded into the three-dimensional ordered periodic micro-nano structure array by using a way of a hydro-thermal synthesis method. A SERS activity basement of the invention can achieve homogenization from a centimeter grade to a large area. The invention designs SERS activity hot-particles on the three-dimensional ordered micro-nano structure, and assembles increasing effect of antenna, the increasing effect of metal/semiconductor intersection and the increasing effect of a gap into one body, then high sensitivity of the SERS activity is obtained, and the SERS activity hot-particles is firmly embedded into the tree micro-nano structure, then the invention is not only applicable for a SERS test of trace liquid-phase analyte, but also for the SERS test of trace gaseous-phase analyte.

The invention relates to a synthesis method of D,L-danshensu isopropyl ester. The method comprises taking protocatechuic aldehyde as an initial raw material, protecting phenolic hydroxyl by benzyl, carrying out Darzens epoxidation, followed by carrying out catalytic reduction with palladium catalyst/hydrogen or Raney nickel/hydrogen, and thus obtaining the D,L-danshensu isopropyl ester. The purity of the product synthesized by the method can reach 98%, and the yield can reach 55%. Moreover, the synthesis method has the advantages of simple and easily obtained raw materials, short routes and high yield, and is suitable for large-scale industrialized production.

The invention relates to a synthesis method of fine grain ZSM-5 zeolite molecular sieve with high silicon aluminium ratio, which comprises using a surface active agent, charging it into acidified aluminium salt solution, then slowly dropping alkaline solution formed from sodium silicate, template agent and seed crystal into aluminium saline solution, the overall composition of the obtained reaction mixture being Na2O:Al2O3:SiO2:H2O=1.5-4.0:1:20-280:500-2000 by mol ratio, then subjecting the reaction mixture to thermal crystallization through the conventional method.

The invention discloses a graphene nano sheet/MoS2 composite nano material and a synthesis method thereof. The method comprises the following steps of: preparing a graphite oxide nano sheet from graphite by using a chemical oxidation method, then dissolving molybdate into deionized water to form a solution of 0.02 to 0.07M, and adding thioacetamide or thiourea serving as a sulfur source and a reducer, wherein the mass ratio of the thioacetamide or the thiourea to the molybdate is 5:1-12:1; and adding the graphite oxide nano sheet into the solution, performing ultrasonic treatment for 1 to 2 hours so that the graphite oxide nano sheet is fully dispersed in a hydrothermal reaction solution, transferring the mixture into a hydrothermal reaction kettle, sealing, reacting for 20 to 36 hours at the temperature of between 220 and 260 DEG C, and obtaining the graphene nano sheet/molybdenum disulfide composite nano material by one-step hydrothermal synthesis, wherein the mass ratio of the graphene nano sheet to the molybdenum disulfide in the composite material is 1:2-4:1. The method has the characteristics of mild reaction condition and simple process. The synthesized graphene nano sheet/molybdenum disulfide composite nano material serving as an electrochemical lithium storage and electrochemical magnesium storage electrode material has wide application.

The invention relates to a synthesis method of racemic bornyl beta-(3,4-dihydroxyphenyl)-alpha-hydroxypropionate. The method comprises the following steps: carrying out Darzens epoxidation on an initial raw material benzyl protected protocatechualdehyde, and carrying out palladium catalyst/hydrogen or Raney nickel/hydrogen catalytic reduction to obtain racemic bornyl beta-(3,4-dihydroxyphenyl)-alpha-hydroxypropionate. The purity and the yield of a product synthesized by adopting the method reach 98% and 48.6% respectively. The synthesis method has the advantages of simple and easily available raw material, short route, high yield, and suitableness for large scale industrialized production.

The invention discloses a normal-temperature synthesis method for a polycarboxylic acid water-reducing agent, and belongs to the field of cement concrete water-reducing agents. The water-reducing agent is prepared by the following steps of: copolymerizing polyoxyethylene ether monomer or polyoxyethylene ester monomer a containing unsaturated double bonds, unsaturated monocarboxylic acid and derivative monomer thereof b, unsaturated dicarboxylic acid c and unsaturated sulfonic acid or salt monomer thereof d in aqueous solution under the action of an oxidation reduction initiator, and finally neutralizing the solution by using alkali solution to obtain the water-reducing agent. The reaction can be performed at room temperature by adopting an oxidation reduction initiating system, and the appropriate reaction temperature is between 5 and 30 DEG C; and the synthesis process does not need heating, so energy is saved, and high-temperature side reaction is effectively controlled. The prepared polycarboxylic acid high-performance water-reducing agent has the characteristics of high water-reducing rate and good collapse protecting performance. The water-reducing agent has wide application range, and the method has low production process requirement and is suitable for industrialized large-scale production.

The present invention provides substantially monodisperse colloidal nanocrystals and new preparative methods for the synthesis of substantially monodisperse colloidal nanocrystals. These synthetic methods afford the ability to tune nanocrystal size and size distribution. By using non-coordinating solvents in the synthetic process, these procedures constitute easier, less expensive, safer, and more environmentally “green” methods than those currently in use. This invention is generally applicable to any II-VI or III-V semiconductor material, and may be useful in generating metal-nonmetal compounds involving transition metals as well.

The invention discloses a training method for multiple personalized acoustic models, a voice synthesis method and a voice synthesis device. The training method comprises the following steps: training a reference acoustic model according to first acoustic feature data of training voice data and first text annotation data corresponding to the training voice data; acquiring voice data of a target user; training a first target user acoustic model according to the reference acoustic model and the voice data; generating second acoustic feature data of the first text annotation data according to the first target user acoustic model and the first text annotation data; training a second target user acoustic model according to the first text annotation data and the second acoustic feature data. According to the model training method disclosed by the embodiment, in a process of training a target user acoustic model, the requirement on the scale of voice data of the target user is lowered, and a plurality of personalized acoustic models including the voice features of the target user can be trained by using a small amount of user voice data.

The present teachings are directed toward single metal and alloy nanoparticles and synthesis methods for preparing single metal and alloy nanoparticles.

The invention is a styrene or alpha olefine polymerization catalyzer, the synthesizing method and the use. The catalyzer is a pyridyl di-imine back-transition metal suitable matter, synthesized by pyridyl di-imine and back-transition metal compound and can catalyze the polymerization of styrene or alpha-olefine. The product is mainly ruleless polystyrene.

Synthetic methods for the manufacture of segmented nanoparticles are described.