11104 results about "Synthesis methods" patented technology

This invention discloses methods for preparing compositions of cyclodextrin polymers for carrying drugs and other active agents. Methods are also disclosed for preparing cyclodextrin polymer carriers that release drugs under controlled conditions. The invention also discloses methods for preparing compositions of cyclodextrin polymer carriers that are coupled to biorecognition molecules for targeting the delivery of drugs to their site of action. The advantages of the water soluble (or colloidal) cyclodextrin polymer carrier are: (1) Drugs can be used that are designed for efficacy without conjugation requirements. (2) It will allow the use of drugs designed solely for efficacy without regard for solubility. (3) Unmodified drugs can be delivered as macromolecules and released within the cell. (4) Drugs can be targeted by coupling the carrier to biorecognition molecules. (5) Synthesis methods are independent of the drug to facilitate multiple drug therapies.

A self-immolative dendrimer capable of releasing all of its tail units upon a single cleavage event, methods of synthesizing same and uses thereof are disclosed.

Methods of improving the kinetics of bimolecular interactions where reactants are present in low concentrations are provided. Methods of pre-amplifying one or more oligonucleotides using high concentration universal primers are provided. Methods of improving the error rate in oligonucleotide and/or polynucleotide syntheses are also provided. Methods for sequence optimization and oligonucleotides design are further provided.

The present invention relates to a synthesis method of carbon nanotubes, and more particularly to an apparatus for a mass synthesis of carbon nanotubes in gas phase using an atmospheric-pressure microwave plasma torch. The method and apparatus is described for the continuous production of carbon nanotubes by making use of a microwave plasma torch operated at a frequency of 2.45 GHz, by introducing a transition metal catalyst precursor and a carbon containing gas into the microwave plasma torch to produce atomized catalyst metal and to decompose the carbon containing gas, by passing the resulting gaseous mixtures through a furnace, and by quenching rapidly and collecting the products so formed at the exit of the furnace. The resultant products are the carbon nanotubes.

The invention discloses a remote sensing image classification method based on multi-feature fusion, which includes the following steps: A, respectively extracting visual word bag features, color histogram features and textural features of training set remote sensing images; B, respectively using the visual word bag features, the color histogram features and the textural features of the training remote sensing images to perform support vector machine training to obtain three different support vector machine classifiers; and C, respectively extracting visual word bag features, color histogram features and textural features of unknown test samples, using corresponding support vector machine classifiers obtained in the step B to perform category forecasting to obtain three groups of category forecasting results, and synthesizing the three groups of category forecasting results in a weighting synthesis method to obtain the final classification result. The remote sensing image classification method based on multi-feature fusion further adopts an improved word bag model to perform visual word bag feature extracting. Compared with the prior art, the remote sensing image classification method based on multi-feature fusion can obtain more accurate classification result.

The invention provides an automatic synthesis method for a facial image. A user inputs two facial source images, a target image and semantic information of an area to be edited; a model matching module utilizes an active appearance model to automatically search an image and provide facial shape information and facial texture information of the facial image; then, the shapes of the two facial images are aligned by using the characteristics of the model, and the shapes of the source images in the edited area are aligned to a corresponding area in the target image by virtue of the deformation of a sheet sample band; a characteristic synthesis module is used for characteristic synthesis for the shape information and the texture information of the aligned source images and the target image, so as to generate a synthetic image automatically; an occlusion processing module is used for occlusion processing the synthetic image, and the occlusion areas of the source images are divided, matched and seamlessly integrated into the target image. Compared with the traditional facial synthesis, the invention integrates the characteristic areas of the two images and solves the problem of image distortion caused by partial face occlusion in the target image.

The invention provides a medical image synthesis method based on double generative adversarial networks. The method comprises the main content of performing data management, generating the generativeadversarial networks, training a U-NET, establishing assessment indexes and obtaining processed pictures, wherein first, a DRIVE database is used to manage a first-stage GAN, then the first-stage GANgenerates a partitioning mask representing variable geometry of a dataset, a second-stage GAN converts the mask produced at the first stage into an image with a sense of reality, an generator minimizes a loss function of the true data in classification through a descriminator, then the U-NET is trained to assess the reliability of synthetic data, and finally the assessment indexes are establishedto measure a generated model. According to the method, by use of a pair of generative adversarial networks to create a new image generation path, the problem that the synthetic image contains a fake shadow and noise is solved, the stability and the sense of reality of the image are improved, and meanwhile image details are clearer.

The invention discloses a quick and efficient synthesis method for silver nanowires. The method comprises the following steps of: 1) introducing inert gas into a reactor, adding 2 volume parts of glycol into the reactor, and stirring, heating, condensing and refluxing the glycol; quickly adding 1 volume part of glycol solution of silver nitrate at molar concentration of between 0.1 and 0.5m into the reactor; slowly dropwise adding 1 to 2 volume parts of PVP at molar concentration of between 0.15 and 0.75m and 4 to 32 mu m of glycol solution of MnCl2 at the same time; and reacting and cooling the mixture to the room temperature to obtain reaction mother liquor of the silver nanowires; and 2) transferring the reaction mother liquor of the silver nanowires into a centrifugal tube; adding acetone into the centrifugal tube and performing centrifugal separation to remove supernatant and retain precipitate; adding de-ionized water or ethanol into the centrifugal tube and performing centrifugal separation to remove the supernatant and retain precipitate, and repeating the operation for 1 to 3 times; and extracting and dispersing the precipitate with ethanol to obtain the silver nanowires. The method shortens the reaction time and also has high selectivity for the synthesis of the silver nanowires under conditions of high concentration.

The invention discloses a preparation method for increasing raman activity of a basement in a surface of a large area of a micro-nano tree structure array, which firstly prepares a large area of a silicon micron cylinder array; a nanometer assembling technology is used for producing a nanometer stick in the silicon micron cylinder array. then a three-dimensional ordered periodic micro-nano structure array is obtained; and various appearance of metal nano-particles are embedded into the three-dimensional ordered periodic micro-nano structure array by using a way of a hydro-thermal synthesis method. A SERS activity basement of the invention can achieve homogenization from a centimeter grade to a large area. The invention designs SERS activity hot-particles on the three-dimensional ordered micro-nano structure, and assembles increasing effect of antenna, the increasing effect of metal/semiconductor intersection and the increasing effect of a gap into one body, then high sensitivity of the SERS activity is obtained, and the SERS activity hot-particles is firmly embedded into the tree micro-nano structure, then the invention is not only applicable for a SERS test of trace liquid-phase analyte, but also for the SERS test of trace gaseous-phase analyte.

The invention relates to a synthesis method of D,L-danshensu isopropyl ester. The method comprises taking protocatechuic aldehyde as an initial raw material, protecting phenolic hydroxyl by benzyl, carrying out Darzens epoxidation, followed by carrying out catalytic reduction with palladium catalyst/hydrogen or Raney nickel/hydrogen, and thus obtaining the D,L-danshensu isopropyl ester. The purity of the product synthesized by the method can reach 98%, and the yield can reach 55%. Moreover, the synthesis method has the advantages of simple and easily obtained raw materials, short routes and high yield, and is suitable for large-scale industrialized production.

The invention relates to a synthesis method of fine grain ZSM-5 zeolite molecular sieve with high silicon aluminium ratio, which comprises using a surface active agent, charging it into acidified aluminium salt solution, then slowly dropping alkaline solution formed from sodium silicate, template agent and seed crystal into aluminium saline solution, the overall composition of the obtained reaction mixture being Na2O:Al2O3:SiO2:H2O=1.5-4.0:1:20-280:500-2000 by mol ratio, then subjecting the reaction mixture to thermal crystallization through the conventional method.

The invention discloses a graphene nano sheet/MoS2 composite nano material and a synthesis method thereof. The method comprises the following steps of: preparing a graphite oxide nano sheet from graphite by using a chemical oxidation method, then dissolving molybdate into deionized water to form a solution of 0.02 to 0.07M, and adding thioacetamide or thiourea serving as a sulfur source and a reducer, wherein the mass ratio of the thioacetamide or the thiourea to the molybdate is 5:1-12:1; and adding the graphite oxide nano sheet into the solution, performing ultrasonic treatment for 1 to 2 hours so that the graphite oxide nano sheet is fully dispersed in a hydrothermal reaction solution, transferring the mixture into a hydrothermal reaction kettle, sealing, reacting for 20 to 36 hours at the temperature of between 220 and 260 DEG C, and obtaining the graphene nano sheet/molybdenum disulfide composite nano material by one-step hydrothermal synthesis, wherein the mass ratio of the graphene nano sheet to the molybdenum disulfide in the composite material is 1:2-4:1. The method has the characteristics of mild reaction condition and simple process. The synthesized graphene nano sheet/molybdenum disulfide composite nano material serving as an electrochemical lithium storage and electrochemical magnesium storage electrode material has wide application.

The invention relates to a synthesis method of racemic bornyl beta-(3,4-dihydroxyphenyl)-alpha-hydroxypropionate. The method comprises the following steps: carrying out Darzens epoxidation on an initial raw material benzyl protected protocatechualdehyde, and carrying out palladium catalyst/hydrogen or Raney nickel/hydrogen catalytic reduction to obtain racemic bornyl beta-(3,4-dihydroxyphenyl)-alpha-hydroxypropionate. The purity and the yield of a product synthesized by adopting the method reach 98% and 48.6% respectively. The synthesis method has the advantages of simple and easily available raw material, short route, high yield, and suitableness for large scale industrialized production.

The invention discloses a normal-temperature synthesis method for a polycarboxylic acid water-reducing agent, and belongs to the field of cement concrete water-reducing agents. The water-reducing agent is prepared by the following steps of: copolymerizing polyoxyethylene ether monomer or polyoxyethylene ester monomer a containing unsaturated double bonds, unsaturated monocarboxylic acid and derivative monomer thereof b, unsaturated dicarboxylic acid c and unsaturated sulfonic acid or salt monomer thereof d in aqueous solution under the action of an oxidation reduction initiator, and finally neutralizing the solution by using alkali solution to obtain the water-reducing agent. The reaction can be performed at room temperature by adopting an oxidation reduction initiating system, and the appropriate reaction temperature is between 5 and 30 DEG C; and the synthesis process does not need heating, so energy is saved, and high-temperature side reaction is effectively controlled. The prepared polycarboxylic acid high-performance water-reducing agent has the characteristics of high water-reducing rate and good collapse protecting performance. The water-reducing agent has wide application range, and the method has low production process requirement and is suitable for industrialized large-scale production.

The present invention provides substantially monodisperse colloidal nanocrystals and new preparative methods for the synthesis of substantially monodisperse colloidal nanocrystals. These synthetic methods afford the ability to tune nanocrystal size and size distribution. By using non-coordinating solvents in the synthetic process, these procedures constitute easier, less expensive, safer, and more environmentally “green” methods than those currently in use. This invention is generally applicable to any II-VI or III-V semiconductor material, and may be useful in generating metal-nonmetal compounds involving transition metals as well.

The invention discloses a training method for multiple personalized acoustic models, a voice synthesis method and a voice synthesis device. The training method comprises the following steps: training a reference acoustic model according to first acoustic feature data of training voice data and first text annotation data corresponding to the training voice data; acquiring voice data of a target user; training a first target user acoustic model according to the reference acoustic model and the voice data; generating second acoustic feature data of the first text annotation data according to the first target user acoustic model and the first text annotation data; training a second target user acoustic model according to the first text annotation data and the second acoustic feature data. According to the model training method disclosed by the embodiment, in a process of training a target user acoustic model, the requirement on the scale of voice data of the target user is lowered, and a plurality of personalized acoustic models including the voice features of the target user can be trained by using a small amount of user voice data.

The present teachings are directed toward single metal and alloy nanoparticles and synthesis methods for preparing single metal and alloy nanoparticles.

The invention is a styrene or alpha olefine polymerization catalyzer, the synthesizing method and the use. The catalyzer is a pyridyl di-imine back-transition metal suitable matter, synthesized by pyridyl di-imine and back-transition metal compound and can catalyze the polymerization of styrene or alpha-olefine. The product is mainly ruleless polystyrene.

Synthetic methods for the manufacture of segmented nanoparticles are described.

The invention provides a method for continuously synthesizing a precursor of a lithium ion battery positive material, relating to an improvement of a synthesis method of a nickle cobalt manganese termary positive material nickle cobalt lithium manganate of the lithium ion battery positive material. The method is characterized in that the synthesis process is as follows: merging a complexing agent ammonia, an aqueous solution of metal nickle cobalt manganese ions and a precipitator sodium hydroxide solution and then continuously adding the substances into a reaction kettle for a synthesis reaction under the strong stirring condition in the presence of protective gas; and aging, filtering and washing the effluent from the reaction kettle, and then drying to obtain the lithium ion battery positive material precursor spherical nickle cobalt manganese termary hydroxide. The method has the advantages that the preparation process is continuous, the particle size of the prepared nickle cobalt manganese compound hydroxide powder is controlled in a range of 5-20 microns, and the prepared nickle cobalt manganese compound hydroxide powder is even in distribution and excellent in electrochemistry property. The method has the advantages of high production efficiency, low production cost and significant economic and social benefits, and the energy is saved.

The invention relates to a football video highlight automatic synthesis method based on an event model. The method comprises the following steps: to a football match video highlight, defining whether a football video highlight clip can be separated into a football video event composed of a plurality of motions; constructing a core-surrounding event model to express a football highlight clip; utilizing football match video and corresponding text narration to construct a training set, selecting goals and red and yellow cards as two types of football highlights, and training the event model; inputting a segment of football match video without narration, identifying an appearance position of a football highlight clip in the input video, and giving a matching mark; according to a user requirement, automatically synthesizing a football highlight clip with a highest mark to be a football video highlight. According to a method of generating the football video highlight in the invention, restriction of factors such as a lens distance of the input video, and the method can be widely applied and popularized to fields of personal digital entertainment, physical education movie and television production and the like.

The invention provides a method for preparing a multilevel porous carbon base composite phase change material, and belongs to the field of composite phase change materials. The method comprises the following steps: at first, preparing an organic metal skeleton material by using such methods as a solution method, a solvothermal method or a stirring synthesis method; with the organic metal skeleton material as a template, high temperature carbonizing under the protection of an inert gas, and changing the carbonizing temperature and the post treatment manner to obtain a multilevel porous carbon material with a super-large specific surface area and a super-large pore volume; selecting proper solvents according to different kinds of phase change core materials, preparing the phase change core materials to a solution, dispersing the porous carbon material into the solution, removing the solvent by such manners as heating, and meanwhile the phase change core materials are adsorbed and limited in the porous carbon material. The composite phase change material prepared by the method provided by the invention has good thermal storage property, can effectively avoid the leakage problem of the phase change core material, and has the advantages of excellent heat transfer property, good cycling stability and wide application range, and the process is simple and is suitable for large-scale production.

Compositions and methods for dual imaging and for dual chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns compounds comprising the structure X₁-Y-X₂, wherein Y comprises two or more carbohydrate residues covalently attached to one another, X₁ and X₂ are diagnostic or therapeutic moieties covalently attached to Y, provided that when Y does not comprise a glucosamine residue, X₁ and X₂ are diagnostic moieties. The present invention also concerns methods of synthesis of these compounds, application of such compounds for dual imaging and treatment of hyperproliferative disease, and kits for preparing a radiolabeled therapeutic or diagnostic compound.

The invention relates to a catalytic synthesis method for polyoxymethylene dimethyl ethers (PODE) by molecular sieves, mainly solving the problem of relatively high cost in the conventional method which adopts trioxymethylene as a raw material. In the method, methanol, methylal and paraformaldehyde are adopted as raw materials based on the mass ratio of (0-10): (0-10):1, the raw materials contactwith a catalyst to react and generate PODE, wherein the dosages of the methanol and the methylal can not be zero at the same time; the reaction temperature is 70-200 DEG C; the reaction pressure is 0.1-6MPa; and the adopted catalyst is selected from at least one of beta zeolite, X zeolite, Y zeolite, ZSM-5 molecular sieve, MCM-22, MCM-56, UZM-8 or SAPO-34 molecular sieve. The technical scheme adopted by the invention solves the above problem preferably, thus being applicable to industrialized production of the PODE.

The invention relates to a hydrogen storage material, in particular to a load porous metal organic hydrogen storage material, being a load metal-porous metal organic compound composite material. The hydrogen storage material is made according to the following steps: (1) inorganic salt and organic acid are used as reagents, water or an organic solvent is adopted, a porous metal organic compound is prepared by a hydro-thermal synthesis method or a solvent-thermal synthesis method; (2) the porous material is loaded by soluble metal salt; the load metal-porous metal organic compound composite material is made by adopting a liquid phase method or a hydrogen reducing method; the loading amount of the metal is 2 to 20 percent of the mass of the composite material. The hydrogen storage material has simple preparation process and low cost; the chemical modification of the organic frame material of the porous metal can effectively improve the hydrogen absorbing and releasing performance of the material under a moderate condition, thereby providing a novel hydrogen storage material which realizes good hydrogen absorbing and releasing under the moderate condition.

Zearalanol compounds are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various disorders. Methods of synthesis and use of such compounds are also described and claimed.

In one embodiment of the present disclosure, a series of conjugated polymers used, among other things, as polymer solar cell or polymer photovoltaic device active layer materials, is provided. In one embodiment, the conjugated polymers have the general structure and formula shown in (I), wherein: R1 and R2 are independently selected from proton, halogens, alkyls, aryls and substituted aryls; Ar is selected from the group consisting of monocyclic, bicyclic and polycyclic arylene, or monocyclic, bicyclic and polycyclic heteroarylene. In another embodiment, the conjugated photovoltaic polymers are comprised of repeated units having the general structure of formula (II), wherein, R1, R2, R3, R4, R5, and R6 are independently selected from proton, alkyls, halogens, aryls, substituted aryls, and other kinds of substituents. Synthesis methods of several polymers of the present disclosure are provided, and absorption spectra and electrochemical cyclic voltammetry data of some polymers, and also the photovoltaic properties of the polymers in this present disclosure are also provided.

The invention relates to a video abstraction method based on moving target detection, and the method comprises the following steps of: carrying out moving target detection and analysis processing on an initial image sequence frame so as to obtain visual feature information of a moving object in each frame of an original video, carrying out target tracking and merging processing between frames and extracting index information of each moving target of the original video; reordering each moving target in time and space, and generating an abstract video by fusing background images, and recording the index information of each moving target in the abstract video; and establishing index correlation for moving targets of each frame of the abstract video and the moving targets of the original video. The invention further discloses a video abstraction device based on moving target detection. The target tracking synthesis method provided by the invention is simple and effective, and can be used for achieving fast and accurate abstraction and concentration of a surveillance video; and the use of index allows freely convenient browsing of the original video clip to which the moving objects occur during playing. The video abstraction method and system based on moving target detection can be used for generating an abstract video at a fast speed, are high in accuracy, and are easily used.

The invention discloses a controllable synthesizing method of an N-doped graphitized carbon ball with hollow structures. The method comprises the following steps: (1) dissolving silicon source, soluble metal salt and a catalyst to the solvent according to the molar ratio, transferring the solvent to the thermal water kettle to conduct hydro-thermal synthesis after being stirred until being thoroughly dissolved, and cleaning, filtering and drying the sediment to obtain a primary commodity; (2) reducing the primary commodity at high temperature under the protection of gas in a high-temperature reaction furnace; and (3) soaking the product obtained by high-temperature reducing in acidic solution, and obtaining the graphitized carbon ball nitrogen doping with the hollow structure after cleaning, filtering and drying. The graphitized carbon ball with the hollow structures provided by the invention has the advantages that the carbon sphere has a uniform appearance, the carbon shell has millipore structures, a mesoporous carbon support structure is formed inside the carbon sphere and a better graphitize degree is provided, and can be used in the field of high-efficient catalyzing and transforming, energy storage and transforming, medicine releasing, substance adsorptive separation and the like. The non-template hydrothermal synthesis technique provided by the invention is simple and controllable, and can be used in large scale production.

The invention relates to the field of specific molecular identification and diagnosis reagent and in particular discloses a near infrared fluorescent dye with structural formulas I and II; and the invention also discloses a near infrared molecular probe which is obtained through covalent bonding between the near infrared fluorescent dye with the structural formulas I and II and a ligand of specific molecules. The near infrared molecular probe can be used for early diagnosis of turmour diseases.