183results about "Oxygen-containing compound preparation" patented technology

The present invention relates to novel iminoamide-type compounds of the general formula (I) and use thereof as ligands in copper-catalyzed coupling reactions of (hetero)aryl halides forming C-C, C-N, C-S, C-O, C-P-bonds and other bonds, in particular the use of the compounds of formula (I) as ligand in copper-catalyzed coupling reactions of aryl halides forming C-O-bonds.

The invention discloses a novel injection containing edaravone and high-purity synthesized (+)-2-borneol, because the (+)-2-borneol is prepared by a chemical synthesis process, the curative effect of the (+)-2-borneol is better than that of natural borneol and (+)-2-borneol extracted from the natural borneol under the same dosage, the toxic and side effects can be reduced, and the product quality is more stable; and the established GC-MS analysis method can more accurately control the content of each coexisting substance and better guarantee the shelf life quality. The injection is more suitable for improving the treatment effect on central nervous system diseases, oxidative stress injuries such as diabetes, retinopathy, diabetic peripheral neuropathy and neurodegenerative diseases and thrombus-related diseases.

The invention relates to a preparation method of 4-chlorophthalic acid, and relates to the technical field of organic synthesis.The preparation method of 4-chlorophthalic acid comprises the following steps that a compound 1 and alcohol are subjected to an alkoxylation reaction, and a compound 2 is obtained; in a reaction system containing acetic acid, the compound 2 and pypocholoride are subjected to a chlorination reaction, and a compound 3 is obtained; and sequentially carrying out hydrolysis reaction and acidification reaction on the compound 3 to obtain the 4-chlorophthalic acid. Compared with the existing 4-chlorophthalic acid monosodium salt technology, the preparation method of 4-chlorophthalic acid provided by the invention has the advantages that by adding acetic acid in the chlorination reaction, the reaction temperature is increased, the reaction time is shortened, the cost is reduced, and the defects in the prior art are made up.

The invention discloses a synthesis method of 2, 4, 5-trifluorophenylacetic acid, which comprises the following steps: by taking cheap and easily available o-chloronitrobenzene as a raw material, reacting with sodium nitrate in a sulfuric acid and trifluoroacetic acid system, separating generated 2, 4-dinitrochlorobenzene through melt crystallization, and continuing to synthesize 2, 4-dinitrochlorobenzene in methyl chloroacetate to obtain 2, 4, 5-trifluorophenylacetic acid. The method comprises the following steps: carrying out indirect aromatic nucleophilic substitution reaction on 2, 4-dinitrophenylacetic acid under the condition of sodium hydride to generate 5-chloro-2, 4-dinitrophenylacetic acid methyl ester, separating, carrying out fluorination reaction on the 5-chloro-2, 4-dinitrophenylacetic acid methyl ester and potassium fluoride under the action of a phase transfer catalyst, carrying out rectification separation to obtain 2, 4, 5-trifluorophenylacetic acid, and carrying out hydrolytic acidification on the 2, 4, 5-trifluorophenylacetic acid in a sodium hydroxide aqueous solution to obtain 2, 4, 5-trifluorophenylacetic acid. And the process route is safer, more environment-friendly, more efficient and lower in cost.

To provide a technique capable of inexpensively decomposing a polyester resin without using an expensive useful chemical substance as a material.SOLUTION: A method for decomposing a polyester resin brings a polyester resin into contact with a solid of an oxide or a hydroxide having a standard oxidation reduction potential in the water higher than a standard oxidation reduction potential of water in the water, and hydrolyzes the polyester resin.SELECTED DRAWING: Figure 1

The invention discloses a recovery process of waste PET (polyethylene glycol terephthalate), which comprises the following steps: dissolving waste PET by using a good solvent, dropwise adding into cold methanol, precipitating, filtering, separating, drying, and hydrolyzing the waste PET by using a low-concentration sodium hydroxide aqueous solution, so that the PET can be effectively hydrolyzed at a relatively low temperature (25-40 DEG C), the reaction conditions are mild, the reaction time is short, the yield is high, and the recovery process is suitable for industrial production. The yield of the product TPA is up to 99%, the product TPA is easy to separate, and the solvent can be recycled.

The invention discloses a method for depolymerizing polyester. The method comprises forming a polyester comprising the following components (a), (b) and (c): (a) a polyester, (b) one or more basic compounds selected from the group consisting of alkali metal hydroxides, alkali metal carbonates, alkali metal bicarbonate salts, alkaline earth metal hydroxides, alkaline earth metal carbonates and alkaline earth metal bicarbonate salts, and (c) and a step of depolymerizing the polyester in the mixture of a solvent containing at least one of an alcohol-based solvent and a ketone-based solvent. The temperature of the mixture at the time when the mixture containing the total amount of the polyester, the basic compound, and the solvent is formed is 75 DEG C or less. The ratio of the amount of the polyester to the amount of the solvent is 0.2-20 by mass.

The present invention relates to a method for producing terephthalic acid in an environmentally friendly manner using waste polyester. In particular, according to one embodiment of the present invention, the method for producing terephthalic acid includes the steps of (1) subjecting waste polyester to alcoholysis using C4 or higher alcohol to produce a liquid composition containing the compound represented by formula 1, and (2) subjecting the liquid composition to hydrolysis, and thus can produce terephthalic acid in an environmentally friendly manner, improve processability, and reduce process costs.

The invention provides a preparation method of unsaturated fatty acid, which obviously reduces the residual amount of dioxin in grease through tromethamine treatment, effectively separates EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) through magnesium acetate precipitation, and improves the cycle use frequency of silver nitrate cycle use liquid through stannous chloride treatment and alkaline alumina treatment. And the unsaturated fatty acid separation capability of the silver nitrate recycling liquid is maintained.

The invention belongs to the technical field of separation, and particularly relates to a separation process of ethyl acetate and butanone, which comprises the following steps: a butanone-ethyl acetate-ethanol mixture to be treated enters the middle part of a butanone separation tower, liquid produced from the top of the butanone separation tower is continuously introduced into an ethanol separation tower, and a butanone product is continuously produced from the bottom of the butanone separation tower; continuously introducing tower top produced liquid of the ethanol separation tower into an ethyl acetate separation tower, and continuously producing an ethanol product from the tower bottom of the ethanol separation tower; liquid produced from the top of the ethyl acetate separation tower returns to the butanone separation tower, and ethyl acetate products are continuously produced from the bottom of the ethyl acetate separation tower. According to the method, the ethanol is introduced as an entrainer, the azeotropic ratio of the ethanol to the ethyl acetate and the butanone is obviously changed by changing the operation pressure, and the operation is performed in different rectification areas generated under different pressure conditions, so that the operation difficulty of direct pressure swing rectification separation of the ethyl acetate and the butanone is reduced, and the separation of the ethyl acetate and the butanone is realized.

The invention discloses a device and a method for removing free fatty acids from waste vegetable oil, and belongs to the technical field of devices and methods for removing free fatty acids from waste vegetable oil. The device comprises a tank body, a heater and a control cabinet, and is characterized in that the tank body comprises a reaction layer and a separation layer, a waste vegetable oil inlet pipe is arranged at the left part of the reaction layer, an alkali solution inlet pipe is arranged at the right part of the reaction layer, a steam inlet pipe is arranged at the upper part of the reaction layer, a stirring device is arranged in the reaction layer, the stirring device comprises a shell, a connecting rod, a fixing rod and a stirring paddle, a rotating shaft is arranged in the shell, a group of moving blades are arranged on the rotating shaft, a group of fixing frames are arranged between the inner wall of the reaction layer and the shell, a steam exhaust pipe is arranged between the fixing frames on the left part of the shell, the right end of the steam exhaust pipe is arranged between the fixing frames and passes through the left part of the shell, a circuit box is arranged on the right side of the reaction layer, a water vapor exhaust pipe, a waste vegetable oil inlet pipe, an alkali solution inlet pipe, a soap solution exhaust pipe and a glycerin exhaust pipe are arranged in the circuit connection box in order from top to bottom, a solenoid valve 1 is arranged on the water vapor exhaust pipe, a control box is arranged at the bottom of the circuit connection box, a circuit line is connected with the control box, and a control panel is arranged on the control box.

To provide a method for producing a cyclohexanedicarboxylic acid-based compound which can simply obtain a cyclohexanedicarboxylic acid-based compound such as DMCD from a polymer having a terephthalic acid skeleton at a sufficient yield at low cost.SOLUTION: A method for producing a cyclohexanedicarboxylic acid-based compound includes performing exchange reaction of an ester group or an amide group and alcohol or water in the presence of a catalyst A, and nuclear hydrogenation reaction in the presence of the catalyst A and a nuclear hydrogenation catalyst B, on a polymer having a terephthalic acid skeleton containing an ester group or an amide group, and thereby obtaining a cyclohexanedicarboxylic acid or a cyclohexanedicarboxylic acid ester, wherein the catalyst A containing at least one selected from Group 2 elements (excluding strontium) and Group 3 elements, and the nuclear hydrogenation catalyst containing at least one selected from a catalyst containing ruthenium, and a platinum-carrying catalyst in which platinum is carried on silica are used.SELECTED DRAWING: None

Depolymerization of polyalkylene terephthalate resin using Alcosilis, providing a superior depolymerization method. [Solution] The method for depolymerizing a polyalkylene terephthalate resin according to the present disclosure is a method for depolymerizing a polyalkylene terephthalate resin by alcoholization of the polyalkylene terephthalate resin, wherein the polyalkylene terephthalate resin includes a polybutylene terephthalate resin, and the alcohol used for alcoholization contains tetrahydrofuran in a proportion of more than 0 ppm by mass and 100,000 ppm or less by mass.

The present invention provides a method for asymmetric synthesis of cyclobutane derivatives. Compound 2 and PhBpin are used as substrates, and are mixed with a catalyst, a ligand, an additive, an oxidant, a base, water, and a solvent for reaction to generate a target compound 1. The reaction formula is as follows: wherein R 1 The present invention forms a chiral complex by using a chiral α-amino spirocyclic ligand and a Pd(II) center, thereby achieving high yield and high enantioselectivity and providing a new approach to the asymmetric synthesis of cyclobutane derivatives.

The invention relates to a method for synthesizing (R)-3-methylheptanoic acid. According to the method, the application range of steroid sapogenin degradation waste is further expanded. According to the method disclosed by the invention, the (R)-3-methyl-heptanoic acid can be conveniently obtained by taking the (R)-4-methyl-gamma-butyric acid lactone obtained by degrading steroid sapogenin as a raw material. According to the method provided by the invention, the use of highly toxic and controlled reagents is avoided, high-risk reactions such as hydrogenation in the prior art are avoided, and the method is mild in reaction condition and low in synthesis cost. Meanwhile, the utilization rate of steroid sapogenin resources is increased, and waste generated in the utilization process of the steroid sapogenin resources is reduced.

The present invention discloses an auxiliary material feeding device for glycerol production, which relates to the field of glycerol processing. It includes a reaction tank, wherein vegetable oil and sodium hydroxide solution are poured into the interior of the reaction tank. A stepping motor is arranged at the top of the adjusting plate, and an output end of the stepping motor is provided with a telescopic shaft mechanism. The telescopic shaft mechanism is connected to a lifting mechanism, and an activated carbon stirring disk is arranged on the telescopic shaft mechanism. Activated carbon balls are hung on the activated carbon stirring disk. In the present invention, the activated carbon balls to be treated are placed inside the arc-shaped blades. The activated carbon balls inside the arc-shaped blades are thrown out from the ports of the arc-shaped blades under the action of centripetal force, and the arc-shaped blades will stir the activated carbon balls to move in the solution and adsorb pigments. When the stirring disk rotates in the reverse direction, the arc-shaped blades will expand away from the stirring disk, and the activated carbon balls will penetrate through the storage port and enter the interior of the arc-shaped blades for re-collection and salvage.

The invention discloses a butyl-containing waste liquid treatment method, and belongs to the technical field of chemical engineering, the method comprises the following steps: converting 1-chlorobutane into n-butyl alcohol through alkaline resin, hydrolyzing n-butyl acetate in an alkaline reagent to obtain n-butyl alcohol, and then recovering high-purity n-butyl alcohol through extractive distillation; according to the method, the n-butyl alcohol is efficiently recovered from the waste liquid and returns to the front end again to serve as a raw material to be input, and the resin and the extraction agent used in the method can be recycled; and the treated waste liquid is simple to treat and low in cost, so that the production cost of preparing glufosinate-ammonium is reduced, the pollution to the environment is reduced, and the method has very high industrial application value.

To achieve high-yield recovery of dicarboxylic acids and diols, which are polyester monomers, from a polyester composition containing an acrylic component and / or a silicone component.SOLUTION: The present invention provides dicarboxylic acid and / or diol obtained by a process that involves hydrothermally decomposing a polyester composition including an acrylic component and / or a silicone component and a polyester component, at 180°C or more and 350°C or less in the presence of an alkaline component.SELECTED DRAWING: None

The invention discloses a biodegradable polyester recovery method, which comprises: carrying out a hydrolysis reaction on biodegradable polyester in the presence of a catalyst, wherein the catalyst is selected from ferric chloride and / or strong acid. The method is simple, environment-friendly, low in cost, high in recovery rate and suitable for industrial production.

The invention discloses hump conjugated linoleic acid, a hump conjugated linoleic acid microcapsule and a preparation method and application of the hump conjugated linoleic acid microcapsule, and belongs to the technical field of deep processing of hump fat. According to the method, petroleum ether is used as a solvent, crude fat is extracted from hump fat through a Soxhlet extraction method, NaOH-ethanol is used for saponifying the crude fat, then a low-temperature crystallization method is combined with a urea adduction method, and finally, the conjugated linoleic acid is effectively separated and purified. The determination of the free radical scavenging ability of DPPH and ABTS shows that the obtained CLA has oxidation resistance. Extracted and purified conjugated linoleic acid is used as a core material, whey protein isolate and maltodextrin are selected as wall materials, an emulsion is prepared, and microcapsule powder is prepared by a direct vacuum freeze-drying method. Experiments show that the prepared conjugated linoleic acid microcapsule has a complete structure and good thermal stability.

To improve the recovery rate of alcohol, which is a constituent monomer of polyester resin, in a method for decomposing polyester resin using high-temperature water. [Solution] A method for decomposing polyester resin, comprising step (i) of hydrothermally treating polyester resin in the presence of polyamide resin, wherein step (i) includes proceeding with hydrolysis of the polyester resin at a temperature of 150°C or higher.

The present invention provides, inter alia, a process for preparing a compound of formula (I) wherein the substituents are as defined in claim 1. JPEG2025515043000048.jpg33159

The invention relates to novel salts of N-substituted 2-amino-4-methylpyrimidine-5-yl-carboxylic acids having the formula (I), where the values of the radicals are disclosed in the claims, and the use of said salts as a growth stimulator for plants and fungi. The invention further relates to embodiments of methods for producing N-substituted 2-amino-4-methylpyrimidine-5-ylcarboxylic acids having the formula (I). The technical result is the production of novel salts of N-substituted 2-amino-4-methylpyrimidine-5-yl-carboxylic acids having the formula (I) which exhibit improved plant growth stimulator properties.

The present invention proposes a synthetic method for 8-oxo-2,2,14,14-tetramethylpentadecanedioic acid, the method comprising: (1) adding water and lithium hydroxide to a reaction vessel, heating and stirring until clarified; (2) adding a mixed solution containing 8-oxo-2,2,14,14-tetramethylpentadecanedioic acid diethyl ester and dimethyl sulfoxide to a container; (3) stirring the reaction solution obtained in the previous step and heating to a predetermined temperature, insulating and stirring for a predetermined time, so as to obtain the 8-oxo-2,2,14,14-tetramethylpentadecanedioic acid. Utilizing the method of the present invention, 8-oxo-2,2,14,14-tetramethylpentadecanedioic acid can be efficiently synthesized, and the product purity is high, the impurities are few, and the yield is high. In the post-processing process, there is no need to refine with an organic solvent such as methyl tert-butyl ether, which is more environmentally friendly, safe, reduces production costs, simplifies operation, and is suitable for industrialized large-scale production.

A growth inhibitor for forming a thin film, a method for forming a thin film using the same, and a semiconductor substrate prepared therefrom are disclosed. The growth inhibitor is represented by Chemical Formula 1 [AnBmXo]. In the Chemical Formula 1, A is carbon or silicon, B is hydrogen or a C1-C3 alkyl, X is a halogen, n is an integer from 1 to 15, o is an integer of 1 or more, and m is from 0 to 2n+1. Side reactions are suppressed to appropriately lower a thin film growth rate and remove process byproducts in the thin film, thereby preventing corrosion or deterioration and greatly improving step coverage and thickness uniformity of a thin film even when the thin film is formed on a substrate having a complicated structure.

The invention relates to a method for removing heavy metals in borneol. Specifically, the invention provides a method for reducing the content of heavy metals in borneol, and the method comprises the following steps: (1) mixing a borneol crude product with an organic solvent to obtain a borneol crude product solution; and (2) adding propolis and activated carbon into the borneol crude product solution obtained in the step (1), stirring, filtering, concentrating the filtrate under reduced pressure, crystallizing and filtering the obtained concentrated solution, and drying the obtained solid to obtain the borneol pure product, thereby reducing the content of heavy metals in the borneol. The method provided by the invention can effectively reduce the content of heavy metals such as arsenic, lead, mercury, cadmium and copper in the borneol, so that the heavy metals in the borneol can be effectively controlled, and the application value of the borneol is improved.

[Problem] To provide a method for recycling a polyester-containing substance by a new means. [Solution] The method for recycling a polyester-containing substance comprises a step in which the polyester-containing substance is subjected to alcoholysis in a solvent in the presence of a catalyst and an alcohol and a step in which an alcoholysis product obtained in the above-mentioned step is isolated. Specifically, the method is performed using a device including a tank for holding a polyester-containing substance therein and a tank and / or a path for isolating a product of alcoholysis of the polyester.

This invention provides a novel method for manufacturing fluorinated carboxylate compounds, for producing formula (P1): (B 1f ) mp (A) 1 ) np [B] 1f RfCOO; Rf is a hydrocarbon group having one or more fluorine atoms; A 1 It is a group other than H; mp is (A 1 The valence of () × np and is 1 or 2; np is mp / (A 1 The valence of A is 1; 1 The method of manufacturing a compound having a valence of 1 or 2 includes: making formula (S1): (B 1f (R) 1 ) [R 1 The compound shown is an organic group and is related to formula (S2): (A 1 ) ms2 (B) 2 ) ns2 [B] 2 It is OH, CO3 or HCO3; ms2 is (B 2 (valence) × ns2 / (A) 1 The valence of ns is 1 or 2; ns2 is (A 1 (value) × ms² / (B) 2 The reaction of the compound or its hydrate shown in the figure (with a valence of 1 or 2) is a step A.

The application discloses a polyester degradation method. Specifically, the polyester degradation method comprises the following steps: degrading the polyester under the action of a carboxylic acid and a catalyst, namely, the polyester is degraded; the polyester comprises repeating units formed by a dibasic carboxylic acid and a dihydric alcohol; and the catalyst is a Lewis acid and / or a sulfonic acid organic acid. The degradation method has wide application range, the obtained product dicarboxylic acid is simple to separate and can be used for resynthesis of the polyester, the catalyst can be recycled and reused, the obtained product dihydric alcohol dicarboxylic acid ester can be reduced by hydrogenation to form a carboxylic acid, and the carboxylic acid and the catalyst in the degradation solution are repeatedly used for degradation of the polyester, so that the industrial benefits of the polyester degradation are maximized.