96 results about "Zeaxanthin" patented technology

The invention discloses a hydroxytyrosol-ergothioneine eutectic crystal as well as a preparation method and application thereof, and belongs to the technical fields of medicines, foods, daily chemicals and the like. The invention provides a hydroxytyrosol-ergothioneine eutectic crystal. The X-ray powder diffraction pattern of the hydroxytyrosol-ergothioneine eutectic crystal has characteristic diffraction peaks at least corresponding to the positions where the 2 theta value is 4.21 degrees + / -0.2 degrees, 8.36 degrees + / -0.2 degrees, 12.29 degrees + / -0.2 degrees, 15.29 degrees + / -0.2 degrees, 19.40 degrees + / -0.2 degrees, 20.98 degrees + / -0.2 degrees, 23.12 degrees + / -0.2 degrees and 28.73 degrees + / -0.2 degrees. According to the hydroxytyrosol-ergothioneine eutectic, the melting point of hydroxytyrosol is increased, the hygroscopicity of hydroxytyrosol is remarkably reduced, and meanwhile the stability of hydroxytyrosol and ergothioneine is enhanced. In addition, after the ergothioneine hydroxytyrosol forms the eutectic crystal, the ergothioneine hydroxytyrosol can also play better anti-oxidation and anti-aging effects.

The invention relates to the technical field of molecular markers, in particular to a biomarker related to the zeaxanthin content character of sweet corn kernels and application of the biomarker. The RIL population is used for performing QTL positioning on the corn kernel zeaxanthin content character, it is found that a major QTL related to the sweet corn kernel zeaxanthin content exists on the sixth chromosome of corn, the major QTL is located between SNP sites Schr6: 83027949 and Schr6: 84835891, the phenotype contribution rate of the corn kernel zeaxanthin content is 18.69%, and the major QTL is a major QTL related to the sweet corn kernel zeaxanthin content. The major QTL can be used for screening or auxiliary screening of sweet corn with relatively high zeaxanthin content, when the genotype of Schr6: 83027949 is GG and the genotype of Schr6: 84835891 is AA, the zeaxanthin content is relatively high, technical support is provided for molecular marker-assisted breeding, and the major QTL has important significance in improving the nutritional quality of the sweet corn.

A trace element supplement consisting of lutein, zeaxanthin, astaxanthin, anthocyanins, and proanthocyanidins is designed to improve retinal health in children and adolescents, relieve eye strain, and slow the progression of myopia. The daily dose is 1–20 mg lutein, 0.2–4 mg zeaxanthin, 0.5–8 mg astaxanthin, 10–700 mg taurine, and 0.5–8.5 mg zinc; the nighttime dose is 1–100 mg eyebright extract, 10–300 mg chamomile extract, 1–200 mg anthocyanins, and 1–500 mg proanthocyanidins.

Disclosed in the present invention is a genetically-engineered Yarrowia lipolytica strain highly producing carotenoids, which is obtained by constructing a xylose-induced activation system in the genetically-engineered Yarrowia lipolytica strain XK17 to control the induced expression of critical enzymes for synthesis of astaxanthin, wherein the critical enzymes for synthesis of astaxanthin comprise β-carotene hydroxylase CrtZ and β-carotene ketonase CrtW. Further disclosed in the present invention is the use of the genetically-engineered Yarrowia lipolytica strain in fermentation production of carotenoids. The present invention starts from the Yarrowia lipolytica strain XK17 highly producing β-carotene, and uses the xylose-induced activation system to separately control the expressions of the β-carotene hydroxylase (CrtZ) and β-carotene ketonase (CrtW) or only control the expression of the CrtW or the CrtZ, thereby separately achieving highly producing astaxanthin, or canthaxanthin, or zeaxanthin under the functions of a proper xylose induction concentration and induction opportunity.

The invention relates to the technical field of nutritious food, and discloses a DHA microcapsule and a preparation method thereof. The DHA microcapsule contains a core material and a wall material, the core material contains DHA oil, squalene and carotenoid, the carotenoid is selected from at least one of beta-carotene, alpha-carotene, lycopene, xanthophyll and zeaxanthine, and the mass ratio of the DHA oil to the squalene to the carotenoid is 1: (0.1-0.55): (0.04-0.16). The DHA microcapsule has relatively low surface oil and a relatively good embedding effect, and active substances in the DHA microcapsule have a relatively high retention rate.

The invention discloses a xanthophyll eye-protecting composition and application thereof, and belongs to the field of traditional Chinese medicine technology and food. The eye protection composition is prepared from the following raw materials in parts by weight: 1 to 50 parts of lutein or lutein ester, 1 to 10 parts of zeaxanthin, 1 to 650 parts of anthocyanin, 1 to 5 parts of docosahexaenoic acid, 1 to 40 parts of radix puerariae, 1 to 40 parts of fructus lycii peptide, 1 to 10 parts of vitamin C and 1 to 15 parts of flos inulae nervosae. According to the composition, the raw materials with the eye protection effect are compounded with the specific new food raw materials including the inula nervosa, the bead peptide powder and the chimonanthus salicifolius, blue light damage of human retinal pigment epithelial cells ARPE-19 and inflammatory response caused by the blue light damage can be effectively relieved, and the composition can have the better eye protection effect.

The present invention discloses a β-carotene-grape seed extract eye-care preparation for retinal protection, relating to functional health foods. The preparation comprises active components and food-acceptable excipients. In parts by weight, the active components include 1–4 parts lutein, 0.5 –2 parts meso-zeaxanthin, 2 – 6 parts β-carotene, 8 – 25 parts blueberry extract, 5 – 18 parts grape seed extract, 0.2–1 part L-ergothioneine, 0.5–3 parts saffron extract, and 1–5 parts phosphatidylserine. The excipients comprise a filler, disintegrant, binder, and lubricant, with a weight ratio of active components to excipients of 1:1 to 1:4. By combining these eight components at specific ratios, the invention achieves synergistic effects, protects retinal health, and reduces blue-light damage. Dual-phase microencapsulation based on solubility, together with standardized preparation steps, improves stability and utilization efficiency.

The present invention provides a highly active composition for resisting blue light damage and a preparation method thereof. The composition includes lutein ester and zeaxanthin; the mass ratio of the lutein ester to zeaxanthin is 1:(0.8-1.5); the lutein ester is added in the form of lutein ester microcapsule powder; and the raw materials of the lutein ester microcapsule powder do not contain other oil components except lutein ester crystals. The present invention combines lutein ester and zeaxanthin to have good antioxidant and blue light damage resistance effects; the raw material lutein ester microcapsule powder used in the present invention solves the instability problem caused by high-temperature melting of lutein ester during the preparation process, effectively avoiding the problem of high-temperature sterilization instability or floating precipitation of the lutein ester microcapsule powder during application.

The application discloses corn silk glucan, a structure formula of which is [→4)-β-D-Glcp-(1→]n, wherein n is 6-60, and a molecular weight range is 1-9.8 kDa. By extracting effective components in corn silk, an extract is obtained, the extract is precipitated by 30-90% ethanol, corn silk crude polysaccharide is obtained, and after the corn silk crude polysaccharide is dissolved, the corn silk crude polysaccharide is sequentially subjected to biological membrane dialysis, ion exchange resin column and HPLC-ELSD separation and purification, and corn silk glucan is obtained. The corn silk glucan and zeaxanthin are compounded to form a glucan compound, the glucan compound can stabilize insulin and improve the activity of the insulin in mouse islet cells, and the glucan compound has 2-5 times stronger hypoglycemic activity than that of zeaxanthin alone, and therefore, the glucan compound has important significance for researching new hypoglycemic drugs or health-care food for assisting hypoglycemia.

The present invention relates to the use of a new strain of the microalgae Chlorella vulgaris Chlorella vulgaris for the production of lutein and zeaxanthin, as well as to the method for obtaining it.

The application provides a fermentation method for increasing the content of zeaxanthin and application thereof in eyesight-improving drinks, and comprises the following steps: S1, mixing fruit residues for pretreatment, S2, enzymolysis, S3, preparation of fermentation medium, and S4, inoculation and fermentation. Through the mixing, pretreatment, enzymolysis and fermentation of seabuckthorn fruit residues, loquat fruit residues and sweet potato skin residues, high-content zeaxanthin is produced, the high-value utilization of solid waste resources is realized, the raw material cost is reduced, the production method of zeaxanthin is effectively expanded, and the equipment requirement is low and easy to popularize on a large scale.

The invention belongs to the technical field of functional food, and particularly relates to a brain-strengthening and eyesight-improving composition as well as a preparation method, a product and application thereof. The composition is prepared from algal oil, linseed oil, arachidonic acid, marigold extract, zeaxanthin suspension oil, NA nervonic acid and PS phosphatidylserine according to a specific weight part ratio. Wherein the marigold extract is prepared by adopting freeze-grinding pretreatment, combining enzymolysis and an ultrasonic-microwave synergistic extraction technology, and performing nanofiltration membrane concentration and vacuum freeze-drying. According to the composition, through the synergistic effect of all the components and an innovative extraction process, the effects of efficiently strengthening the brain and improving eyesight are achieved, and compared with a traditional formula and an extraction method, the component activity retention and the effective component extraction rate are remarkably improved.

This invention discloses a method for preparing avermectin nanoparticles supported on zein-sodium lignin sulfonate, and its applications. The preparation method involves dissolving avermectin and zein in an organic solvent to form a solution (stream 1), and dissolving sodium lignin sulfonate or modified sodium lignin sulfonate in deionized water to form a solution (stream 2). Both streams are simultaneously injected into a dual-channel confined counter-current mixer for rapid mixing. The resulting nanoparticle suspension is then collected, completing the preparation process. This invention utilizes the compatibility of hydrophobic zein with avermectin, combined with the self-assembly properties of zein and the use of sodium lignin sulfonate or modified sodium lignin sulfonate as a stabilizer, to prepare avermectin nanoparticles with high drug encapsulation efficiency and excellent drug release performance. Furthermore, these nanoparticles exhibit excellent resistance to UV photodegradation, effectively reducing the photodegradation of avermectin. The method is simple, rapid, and easy to control.

The invention relates to a lutein zeaxanthin soft capsule and a production process thereof, and belongs to the technical field of health care products. The xanthophyll and the zeaxanthin are used as main active components, and the DHA, the blueberry extract, the glutathione and the lactoferrin are used as auxiliary materials to synergistically enhance the eye protection effect of the capsule. The beeswax, the wheat germ oil and the active ingredients are mixed and homogenized by a high-pressure homogenizer, so that uniform dispersion of the ingredients is ensured, the absorption efficiency of the ingredients is enhanced, and the effect of the capsule is further improved through stability and release control of the active ingredients in wrapping of the active ingredients.

The application provides a method for promoting the weight increase of saffron offsprings by enhancing illumination, comprising the following steps: transplanting the mother corms into the soil for vegetative growth after picking the filaments, the illumination intensity is 20000 Lux, and periodic maintenance management is implemented, water is supplemented once every two weeks, and the morphological indexes of the offsprings are observed, the offsprings are harvested after all the leaves wither. The experimental results show that increasing the illumination intensity reduces the expression level of CsCCD2L in the leaves, increases the content of zeaxanthin, and is conducive to photosynthesis, thereby providing nutrition for the development of the offsprings; the increase of the weight of the offsprings can significantly increase the number of flowers and improve the yield of saffron, and is expected to solve the bottleneck problem of low saffron yield.

Carotenoid compositions are described for management, treatment, and / or prevention of stress by reducing cortisol levels and / or improving distribution and / or density of macular pigment and thus improving overall health status. More particularly, a subject in need thereof for the method has disturbed macular pigment optical density or increased levels of cortisol as markers of psychological and physiological stress. Methods are also described of administering macular carotenoid compositions in daily doses of at least or about 0.005 mg / kg body weight of lutein, and at least or about 0.001 mg / kg body weight of meso-zeaxanthin and zeaxanthin isomer along with at least one food grade excipient and evaluating overall health status. The composition may be derived from plant extract containing xanthophylls and / or xanthophylls esters. The composition also reduces cortisol levels in the blood and relieves physiological stress, thus improving overall health status of a subject in need thereof.

The invention relates to application of zeaxanthine in improving cold resistance of plants, and belongs to the technical field of agriculture. The invention provides an application of zeaxanthine in improving the cold resistance of a plant. The plant is dendrobium nobile. According to the method, zeaxanthine aqueous solutions with different concentrations are sprayed to the low-temperature-stressed dendrobium nobile, and by measuring various parameters of the dendrobium nobile, results show that the yellow leaf rate, the leaf falling rate and the relative electric conductivity of plants can be reduced by spraying the zeaxanthine aqueous solution with the concentration of 50 mg / L to the low-temperature-stressed dendrobium nobile plants, the low-temperature semi-lethal temperature of the plants is reduced, and the yield of the plants is increased. The content of malonaldehyde, soluble protein, soluble sugar, proline and chlorophyll in the plants can be increased, the stress resistance of the plants is enhanced, damage caused by low temperature is relieved, and it is comprehensively known that the cold resistance of the dendrobium nobile can be enhanced by externally applying the zeaxanthine aqueous solution with the concentration of 50 mg / L.

The invention provides a method for promoting weight increase of saffron crocus progeny corms by enhancing illumination, which comprises the following steps: picking filaments, transplanting mother corms into soil for vegetative growth under the illumination intensity of 20000Lux, implementing periodic maintenance management, supplementing water once every two weeks, observing morphological indexes of the progeny corms, and harvesting the progeny corms after all leaves are withered. Experimental results show that the expression level of CsCCD2L in leaves is reduced by increasing illumination intensity, so that the content of zeaxanthin is increased, photosynthesis is further facilitated, and nutrition is provided for development of filial generation corms; the increase of the corm weight of the filial generation can significantly increase the flowering number, improve the yield of saffron crocus, and hopefully solve the bottleneck problem of low yield of saffron crocus.

The present invention relates to a dietary supplement indicated for the treatment of macular degeneration, more specifically a dietary supplement designed to assist in combating macular degeneration. The formulation is based on fish oil (a source of omega-3 TG) combined with cysteine, taurine, lutein, zeaxanthin, and vitamins, supporting visual health through a synergistic action of its components, enhanced by the benefits of omega-3. The present invention also relates to a capsule comprising said dietary supplement and the use of said supplement for combating macular degeneration.

Described herein are methods and compositions that comprise an amount of at least one active agent, such as at least one carotenoid and an ingredient or extract of bilberry, preferably an amount of at least one of: lutein, zeaxanthin, β-carotene, lycopene, and an ingredient or extract of bilberry; and an additive.

The present invention relates to the use of a new strain of the microalgal species Chlorella vulgaris for producing lutein and zeaxanthin, as well as to the method for obtaining it.

The invention discloses an euphausia superba oil composition for promoting growth of retinal cells and improving oxidative damage of the retinal cells and application of the euphausia superba oil composition, and belongs to the technical field of functional foods.The euphausia superba oil composition is prepared from, by weight, 0.1-500 parts of euphausia superba oil, 0.1-25 parts of lutein ester and 0.1-5 parts of zeaxanthin; the content of phospholipid in the euphausia superba oil is greater than or equal to 38 wt%, and the content of omega-3 polyunsaturated fatty acid is greater than or equal to 9 wt%. The raw materials of the composition are easy to obtain, the safety is high, retinal cell proliferation can be promoted, the inhibition effect of H2O2 on retinal cells is improved, H2O2-induced high inflammation and high oxidative stress states are relieved, damage of H2O2 to retinal cells is relieved, and the composition has wide application prospects in the aspect of preparing products for optic nerve protection.

The invention provides a feed additive and feed for improving the quality of poultry eggs and application of the feed additive and the feed, and belongs to the technical field of feed. The invention provides a feed additive, which is prepared from the following components in parts by mass: 20 to 30 parts of lycopene, 10 to 20 parts of capsorubin, 20 to 30 parts of pumpkin powder and 20 to 30 parts of zeaxanthine. Lycopene and zeaxanthine have the effects of resisting oxidation, improving immunity and the like; capsorubin has the effects of resisting oxidation, resisting inflammation, enhancing immunity, resisting cancer and the like; the pumpkin powder has the effects of regulating blood sugar, promoting digestion, delaying senescence, enhancing immunity and the like. According to the feed additive provided by the invention, the lycopene, the capsorubin, the pumpkin powder and the zeaxanthine are combined for use, so that the effects of improving the egg yield of egg laying poultry, improving the egg quality and improving the nutritional value of eggs can be synergistically exerted.

This invention discloses a catalyst composition, a method for preparing zeaxanthin ester, and the zeaxanthin ester itself. The catalyst composition, comprising an alkaline catalyst and a carbonyl iron catalyst, is used to isomerize lutein ester into zeaxanthin ester. Under alkaline conditions, the catalyst composition of this invention allows the carbonyl iron catalyst to complex with the double bond electron cloud of the 4', 5' carbon atom on the terminal benzene ring of the lutein ester molecule, significantly reducing the energy required for the terminal carbon to capture protons. This facilitates the migration of protons from one negative carbon ion site (6' carbon atom) to another site (4' carbon atom), accelerating the transfer of the double bond position. This reduces the activation energy, decreases the amount of alkaline catalyst required, shortens the reaction time, lowers the reaction temperature, and improves the conversion rate and yield of lutein ester.

The utility model discloses a separating device for zeaxanthin microencapsulation preparation, which comprises a box body, the lower end of the box body is fixedly connected with supporting legs, the inner wall of the box body is connected with a screen body in a sliding manner, the box body is provided with a separating mechanism capable of screening, and the separating mechanism is provided with a separating mechanism. The separating mechanism comprises a mounting plate, a driving motor, a connecting shaft, a cam, a mounting block, a groove, a limiting rod, a spring and a supporting rod, the mounting plate is fixedly connected to the outer side of the box body, and the driving motor is fixedly mounted at the upper end of the mounting plate. The sieve body is driven to move, then the sieve body is reset under the action of gravity and elasticity of the springs, materials needing to be separated in the sieve body can be toggled up by repeating the process, the sieve body can be effectively prevented from being blocked by large particles in the mode, and the sieving speed can be increased in the mode that the sieve body is cushioned for sieving.

The present application relates to the technical field of molecular marker, in particular to a biomarker related to the trait of maize xanthophyll content in sweet corn kernels and application thereof. The present application locates QTL of the trait of maize xanthophyll content in kernels by using RIL population, finds that there is one major QTL related to the trait of maize xanthophyll content in sweet corn kernels on the 6th chromosome of maize, which is located between SNP sites S_chr6:83027949 and S_chr6:84835891, and contributes to the phenotype of maize xanthophyll content in kernels by 18.69%, the major QTL can be used for screening or assisting in screening sweet corn with relatively high maize xanthophyll content, when the genotype of S_chr6:83027949 is GG and the genotype of S_chr6:84835891 is AA, the maize xanthophyll content is relatively high, which provides technical support for molecular marker assisted breeding, and has important significance for improving the nutritional quality of sweet corn.

The invention discloses a lycium ruthenicum anthocyanin-containing composition for improving visual fatigue and wet macular degeneration as well as a preparation method and application of the lycium ruthenicum anthocyanin-containing composition, and belongs to the technical field of biological medicines. The composition is prepared from the following raw materials in parts by weight: 50 to 99 parts of lycium ruthenicum anthocyanin extract, 0.5 to 25 parts of lutein ester microcapsule powder and 0.5 to 25 parts of zeaxanthin microcapsule powder. According to the composition disclosed by the invention, the lycium ruthenicum anthocyanin extract, the lutein ester microcapsule powder and the zeaxanthin microcapsule powder are compounded, so that the effect of improving visual fatigue and the effect of improving wet macular degeneration can be improved.

The invention discloses a pharmaceutical composition for preventing birth defects and improving memory, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium and microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including glossy privet fruit, astragalus membranaceus, fructus lycii, semen cuscutae and nucleic acid, and bioactive components including lutein, lutein fat, zeaxanthin, grape seed extract, chlorophyll and taurine. The device is mainly used for pre-pregnancy preparation of pregnant women, dosages thereof, pregnant women and wet nurses. The composition eliminates various factors causing birth defects from multiple systems, multiple links and multiple targets, can significantly reduce the total occurrence rate of birth defects, has the effect of improving memory, is beneficial to the health of parents and children, has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The invention provides application of zeaxanthine in preparation of a product for preventing and / or treating tauopathy, and relates to the field of biological medicine. It is found that zeaxanthine can inhibit expression and abnormal phosphorylation of tau protein and has the effects of prolonging the service life and improving the exercise ability, and a new way is provided for preventing and / or treating tauopathy.

A composition for eye protection against blue light and for the relief of eye fatigue, which is taken once by a child or adolescent, comprises the ingredients in the amounts of: a) lutein in an amount of about 10.0 to about 15.0 mg; b) zeaxanthin in an amount of about 2.0 to about 3.0 mg; c) blueberry extract (Vaccinium corymbosum) in an amount of about 2.5 to about 3.0 mg; d) bilberry extract (Vaccinium myrtillus L.) in an amount of about 2.5 to about 3.0 mg; e) blackcurrant extract in an amount of about 2.5 to about 3.0 mg; f) blackberry juice concentrate in an amount of about 3.0 to about 3.5 mg; g) chokeberry juice concentrate in an amount of about 2.0 to about 2.5 mg; h) vitamin C in an amount of about 10.0 to about 12.0 mg;i) niacin in an amount of about 8.0 to about 10.0 mg;j) vitamin E in an amount of about 6.0 to about 8.0 mg; andk) zinc in an amount of about 2.5 to about 3.0 mg.