The invention discloses a recombinant host cell capable of biosynthesizing cannabinoid phenolic acid, a construction method of the recombinant host cell and a method for biosynthesizing the cannabinoid phenolic acid through the recombinant host cell, and belongs to the field of biotechnology and medicine. The saccharomyces cerevisiae is used as a host, firstly, cannabinoid synthase and cannabinoid phenolic acid synthase are over-expressed in the host, then a metabolic pathway for synthesizing a precursor compound oleylic acid of cannabinoid phenolic acid by using saccharides is constructed in the host, and a metabolic pathway from caproic acid to oleylic acid is further constructed in the host; finally, an endogenous mevalonic acid pathway of a host and a metabolic pathway of acetyl coenzyme A are optimized, the recombinant saccharomyces cerevisiae capable of biologically synthesizing cannabinoid phenolic acid is obtained, a new pathway for producing cannabinoid phenolic acid with high additional value from a cheap carbon source is provided, the production efficiency is high, the period is short, the cost is low, and large-scale production of cannabinoid phenolic acid is facilitated.