86 results about "Lycopersene" patented technology

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of drugs for improving sleep disorder and treating mood disorder or cognitive disorder. The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by mass: 20-30 parts of lycium ruthenicum, 30-40 parts of nitraria fruit, 15-25 parts of gastrodia elata, 13-25 parts of hyperforin perforatum and 2-6 parts of lycopene. The traditional Chinese medicine composition provided by the invention is prepared from lycium ruthenicum, nitraria fruit, gastrodia elata, hyperforin perforatum and lycopene according to a specific ratio, and the composition can effectively relieve anxiety behaviors of chronic stress bound anxiety model mice through ways of resisting oxidation and inflammation, regulating expression of neurotransmitters and the like, prolong sleep time and improve sleep quality. The learning ability and the memory ability of cognitive impairment mice induced by scopolamine are improved, and the neuron density of brain tissues is increased, so that the neuroprotective effect is achieved.

The utility model relates to the field of lycopene content detection, in particular to a sampling device for lycopene content detection, which comprises an outer box body, a panel seat, a top sealing cover and an extraction barrel, a placing groove is arranged on the surface of the outer box body, the panel seat is matched with the right side of the placing groove, the extraction barrel is arranged on the inner side of the panel seat, and the top sealing cover is arranged on the top sealing cover. A through hole is formed in the top of the placement groove, and the top sealing cover is slidably connected with the through hole; the extraction barrel is installed on the panel base, through the split structure of the panel base and the outer box body, the extraction barrel can be conveniently taken out for sampling operation, meanwhile, the extraction barrel can be removed for cleaning, the cleaning effect is guaranteed, meanwhile, the crushing structure is installed on the top sealing cover, cleaning operation of a blade is facilitated, secondary use is facilitated, and the extraction barrel can be conveniently taken out for sampling operation. A filter screen and a filter plate are arranged on the inner side of the extraction barrel, solid-liquid separation operation after tomatoes are smashed is facilitated, liquid enters a bottom liquid storage cavity, solids are retained on the surface of the filter plate, cleaning is conducted by removing the filter plate, and convenience is improved.

The invention relates to a lycopene composition and an emulsion preparation thereof. The lycopene composition is prepared from lutein, beta-carotene, all-trans lycopene, 9-cis lycopene, 11-cis lycopene and 13-cis lycopene. The emulsion preparation also comprises an emulsifier, a co-emulsifier, an antioxidant and water, has good solubility in water, can obtain solutions with chromaticity of L30-35, a35-40 and b25-30, and is concentrated in tone value range and stable in tone coloring.

A heart boosting formulation comprises: L-carnitine, alpha-linolenic acid, citrulline, vitamin D3, lycopene, holy basil, cinnamon and beetroot.

The utility model relates to the technical field of lycopene production, in particular to a lycopene production ingredient blending device which comprises a blending box, a heating sleeve barrel is fixedly connected to the upper end of the blending box, a blending tank is fixedly connected to the interior of the heating sleeve barrel, a lifting air cylinder is fixedly connected to the position, located on the right side of the heating sleeve barrel, of the upper end of the blending box, and a connecting plate is fixedly connected to the output end of the lifting air cylinder; through the use of the stirring rod and the filter barrel I, ingredients are fully stirred and uniformly mixed at different depths, the stirring efficiency is improved, and meanwhile, the scraping blades fully clean and scrape the inner wall of the ingredient tank along with the rotation of the stirring blades, so that the adhesion of the materials is prevented, the mixing effect is improved, the heat transfer is promoted, and blended mixed liquid flows into the filter barrel II; the first filtering barrel rotates to drive the second filtering barrel to rotate synchronously, centrifugal force is generated to conduct double filtration on mixed liquid, the filtering precision is high, and the product quality of lycopene is effectively improved.

The invention provides mutagenic chlorella capable of realizing high yield of phytoene and application of the mutagenic chlorella, and belongs to the technical field of chlorella. The mutagenic algal strain SZU-C49 of the mutagenic chlorella pyrenoidosa is preserved in the Guangdong Microbial Culture Collection Center, the preservation number is GDMCC No: 66780, the preservation time is July 30, 2025, and the preservation address is the 5th floor, No. 59 building, No. 100 Courtyard, Xianlie Middle Road, Guangzhou. The algal strain is obtained by carrying out chemical mutagenesis and screening on a mutagenic chlorella wild type common chlorella original strain. The mutagenic chlorella disclosed by the invention is cultured for 72 hours under an optimized culture condition, the content of phytoene in cells of the strain reaches 25799 mg / g (dry weight) and is more than 100 times that of an original strain, and the mutagenic chlorella can be widely applied to the fields of functional foods, health-care products, cosmetics, medicines and the like.

The invention provides recombinant saccharomyces cerevisiae for producing beta-carotene and application of the recombinant saccharomyces cerevisiae, and belongs to the field of genetic engineering. According to the invention, a beta-carotene metabolic pathway is constructed in saccharomyces cerevisiae, screening is carried out on a key gene lycopene cyclase gene in the metabolic pathway, and site-directed mutagenesis is carried out on lycopene cyclase derived from Rhizomucor circinelloides f. Lusitanius, so that a mutant is constructed. According to the invention, the constructed mutant is expressed in saccharomyces cerevisiae, so that the titer of beta-carotene is remarkably improved.

1. Name of the product in this design: Packaging Box (Lycopene Oleoresin Soft Capsules). 2. Application of this design: This design relates to a packaging box for lycopene oleoresin soft capsules. 3. The key design features of this product are the combination of pattern and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color.

The application provides genes SlSGR1 and SlLCY-B1 for bidirectional regulation of lycopene content in plants and application thereof, relates to the technical field of biotechnology, and discloses application of SlSGR1 protein or related biological materials of the SlSGR1 protein and SlLCY-B1 protein or related biological materials of the SlLCY-B1 protein in regulation of lycopene content in plants. By gene editing, the SlSGR1 protein and the SlLCY-B1 protein are inactivated, the activity of SlPSY1 is improved to promote synthesis, and SlLCY-B1 is inactivated to stop metabolism. SlPSY1 and SlLCY1 interact through PDS, ZDS and CRTISO to improve the content of lycopene. Experiments prove that SlPSY1 and SlLCY-B1 are expressed in fruits, and gene editing does not affect the functions of other genes in the family in stems, leaves and other parts. A new approach for establishing efficient, safe and high-lycopene germplasm is provided.

The invention discloses an efficient and stable lycopene isomerization method which comprises the following steps: dissolving trans-lycopene in an organic solvent, adding a transition metal-based catalyst, adding a catalytic medium (namely confined water molecules) in a reaction system, keeping out of light, heating and stirring, thereby efficiently catalyzing lycopene isomerization. According to the method disclosed by the invention, the isomerization efficiency of cis-lycopene can be improved to 82.2%, which is far higher than 37.6% of thermal isomerization in the prior art; and under the process conditions, the lycopene has a higher retention rate of 90.3%, and later application of the lycopene is facilitated.

The invention discloses a Yarrowia lipolytica engineering bacterium for producing astaxanthin based on a fusion protein method and application of the Yarrowia lipolytica engineering bacterium. A complete astaxanthin synthesis path is expressed in host bacteria by recombinant Yarrowia lipolytica; comprising geranyl geranyl diphosphate synthase CrtE, phytoene synthetase / lycopene cyclase CrtYB, phytoene desaturase CrtI, 3-hydroxy-3-methylglutaryl CoA reductase tHMGR, beta-carotene ketoalcohol enzyme CrtW and beta-carotene hydroxylase CrtZ, and astaxanthin synthesis key enzymes CrtW and CrtZ are subjected to fusion expression by using a short peptide or Linker, so that the astaxanthin is obtained. Meanwhile, the expression of hemoglobin VHb from vitreoscilla is increased; the astaxanthin production performance of the recombinant strain is verified on the basis of protein engineering and fermentation engineering, and the astaxanthin production capacity of the yarrowia lipolytica is further improved.

The application belongs to the technical field of medicine, and particularly relates to a composition for alleviating and repairing testicular damage caused by heat stress and application thereof. The composition for alleviating and repairing testicular damage caused by heat stress comprises the following raw materials: lycopene inclusion compound, ginsenoside Re, modified chitosan nanoparticles and a solvent. The amount of the modified chitosan nanoparticles is 10-15 wt% of the ginsenoside Re. The application innovatively designs a combination formula with lycopene and ginsenoside Re as the core. Both of the two main effective components in the formula are natural plant or traditional Chinese medicine extract, which effectively avoids the conflict between the medicinal properties of traditional Chinese medicines and has good biological safety. The composition can significantly repair the testicular damage caused by heat stress and accelerate the recovery after heat stress damage.

The application discloses a Liriodendron LCYE gene, an expression protein thereof and application, and relates to the technical field of plant genetic engineering.The Liriodendron LCYE gene disclosed by the application comprises LcLCYE gene, or / and LtLCYE gene, or / and variant gene LcLCYE-alpha, or / and variant gene LtLCYE-alpha; and the nucleotide sequences of the genes correspond to SEQ ID NO.1, 3, 5 and 7 respectively.The results of the examples of the application show that the Liriodendron LCYE homologous protein has traditional LCYE enzyme activity, and also has LCYB enzyme activity for catalyzing lycopene to form gamma-carotene and beta-carotene; and the C-terminal structure of the Liriodendron LCYE homologous protein is necessary for the LCYE enzyme activity function, but does not affect the LCYB enzyme activity function.

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, fructus lycii and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.

The application relates to the technical field of vinegar production equipment, and discloses a preparation process for adding lycopene into balsamic vinegar, which solves the problem that the current production and processing steps are relatively complicated because lycopene is added after the vinegar is filled, and the preparation process comprises a base, a packaging bottle conveying mechanism is arranged on the top of the base, a simultaneous feeding mechanism is arranged on the top of the packaging bottle conveying mechanism, and a collecting mechanism is arranged on the simultaneous feeding mechanism; the application is characterized in that the cooperation between the lifting plate, the limiting rod and the U-shaped frame facilitates the longitudinal movement of the lifting plate, the balsamic vinegar feeding pipe and the lycopene feeding pipe can be simultaneously inserted into two adjacent packaging bottles to add balsamic vinegar and lycopene respectively, the packaging bottle located below the lycopene feeding pipe has been added with balsamic vinegar, the simultaneous addition of balsamic vinegar and lycopene can be realized along with the conveying of the packaging bottles, and therefore the production and processing speed is improved.

The invention provides anti-aging oral liquid and a preparation method thereof, and belongs to the technical field of oral liquid. Ginseng, turmeric, astragalus membranaceus and ginger are subjected to bidirectional fermentation through a ganoderma lucidum seed solution, a product is subjected to alcohol precipitation to obtain traditional Chinese medicine polysaccharide, and active components are obtained through freeze drying; the preparation method comprises the following steps: extracting cod skin to obtain a collagen peptide-copper compound, mixing the collagen peptide-copper compound with egg yolk protein for enzymolysis to obtain an egg yolk protein-collagen peptide-copper composition, adding the egg yolk protein-collagen peptide-copper composition into water, embedding the egg yolk protein-collagen peptide-copper composition with active components to obtain an active component embedding solution, adding traditional Chinese medicine polysaccharide, resveratrol, taurine and lycopene, homogenizing and filtering to obtain the anti-aging oral liquid. The anti-aging oral liquid prepared by the invention is simple in preparation method and wide in raw material source, and the prepared oral liquid has excellent anti-oxidation, anti-aging and anti-cancer effects, is relatively low in cost, is easy to realize industrial production, and has a wide application prospect.

The application belongs to the technical field of stem cells, and specifically discloses a mesenchymal stem cell-containing composition and application of the mesenchymal stem cell-containing composition in preparation of a product with an anti-inflammatory effect. The lycopene and oleuropein are added to an activation culture medium. On one hand, the lycopene and the oleuropein can protect the biological activity of the mesenchymal stem cells, improve the immune regulation function of the mesenchymal stem cells, further promote the repair of tissues, improve the proliferation capacity of the mesenchymal stem cells, and promote the generation and secretion of active factors with an anti-inflammatory effect in the mesenchymal stem cells and effectively protect the activity of the active factors. On the other hand, the synergistic effect of the lycopene and the oleuropein can more effectively reduce the tissue damage caused by oxidative stress and inflammation, and significantly improve the anti-inflammatory effect of the composition.

The invention discloses a method for enhancing the synthesis capacity of a yeast double-metabolic-pathway pigment product and application, and belongs to the field of synthetic biology and metabolic engineering. The method comprises the following steps: constructing a saccharomyces cerevisiae engineering strain capable of simultaneously synthesizing violacein and lycopene; constructing a mutant library of the global transcription factor SPT15; transforming the mutant library into the engineering strain, and screening the mutant strain with increased yield based on bacterial colony color visualization. According to the invention, a single global transcription factor SPT15 is modified, so that the cell metabolism is regulated and controlled on the whole, the synergistic interaction of a diheterologous synthesis pathway is realized, and the tedious multi-gene rational modification is avoided. The method is easy and convenient to operate and short in period, and a new strategy is provided for efficient construction of yeast cell factories for high-yield pigment and other double-way products.

The present invention relates to the use of phytoene dehydrogenase (PDS), said method for controlling weeds comprising applying a herbicide containing an effective dose of phytoene dehydrogenase inhibitor (PDSi) to a field in the presence of at least one transgenic plant, the present invention relates to a transgenic plant comprising a polynucleotide sequence encoding phytoene dehydrogenase in its genome, said transgenic plant having reduced plant damage and / or increased plant yield compared to other plants that do not have a polynucleotide sequence encoding phytoene dehydrogenase. The phytoene dehydrogenase PDS1, the phytoene dehydrogenase PDS3, the phytoene dehydrogenase PDS4, the phytoene dehydrogenase PDS5, the phytoene dehydrogenase PDS6, the phytoene dehydrogenase PDS7 and the phytoene dehydrogenase PDS8 have high tolerance to PDS inhibitor herbicides, plants containing the polynucleotide sequence for coding the phytoene dehydrogenase have high tolerance to the PDS inhibitor herbicides, and the phytoene dehydrogenase has high tolerance to diflufenican and diflufenican with the 4-time field concentration. Therefore, the application prospect on plants is wide.

The invention relates to the field of astaxanthin synthesis, and discloses recombinant saccharomyces cerevisiae as well as a construction method and application thereof. The recombinant saccharomyces cerevisiae provided by the invention comprises the following exogenous genes: coding genes of beta-carotene hydroxylase CrtZ, beta-carotene ketolase CrtW, nicotinamide adenine dinucleotide kinase, ferredoxin-NADPH (nicotinamide adenine dinucleotide phosphate) oxidoreductase and ferredoxin; on the basis of the gene, other related genes are further introduced to realize that CrtZ and CrtW are positioned in lipid droplets by lipid droplet targeting peptide Olesion, so that the yield of astaxanthin is increased, finally geranyl-geranyl diphosphate synthase, phytoene dehydrogenase and phytoene synthase are targeted to endoplasmic reticulum through endoplasmic reticulum targeting peptide, and the yield of astaxanthin is increased. Therefore, the yield of the fermentation tank is up to 440mg / L. The recombinant saccharomyces cerevisiae provided by the invention is clear in genetic background, can stably and efficiently produce astaxanthin, and has a wide application prospect.

The invention firstly provides an enzyme system for improving the yield of astaxanthin. The enzyme system comprises beta-carotene hydroxylase crtZ, beta-carotene ketolase crtW and lycopene cyclase crtY which are found by the inventor and have remarkably improved conversion rate. The beta-carotene hydroxylase crtZ has an amino acid sequence as shown in SEQ ID NO: 2, the beta-carotene ketolase crtW has an amino acid sequence as shown in SEQ ID NO: 3, and the lycopene cyclase crtY has an amino acid sequence as shown in SEQ ID NO: 1. On the basis, coding genes of the beta-carotene hydroxylase crtZ, the beta-carotene ketolase crtW and the lycopene cyclase crtY are over-expressed in a basic strain for producing the lycopene, and an escherichia coli recombinant strain for producing the astaxanthin at high yield is constructed. When the recombinant escherichia coli is used for producing astaxanthin through fermentation, the yield and the conversion rate of the astaxanthin are obviously improved; according to the present invention, glycerol is adopted as a substrate, and fermentation is performed in a 5 L fermentation tank for 60 h to obtain 1.54 g / L of astaxanthin (1.18 g / L in the prior art), such that the technical problem of low yield of astaxanthin produced through microbial fermentation in the prior art is solved, the foundation is laid for the industrial production of astaxanthin, and wide application prospects and huge market values are provided.

An entrained polymer is provided that includes in a blended form, a base polymer and a conjugated olefin, optionally lycopene or a derivative thereof. The resulting entrained polymer is useful in the manufacture of packaging for the protection of oxygen-sensitive contents. Also provided are systems and methods for reducing contamination in a product due to oxidation. Also provided are related methods of manufacture and methods of use.

The invention discloses a nutrient composition for improving the male fertility function and a preparation method and application of the nutrient composition. The composition is composed of zinc, selenium, coenzyme Q10, L-acetyl carnitine, folic acid, vitamin D3, natural lycopene, vitamin E, L-arginine and core components such as standardized herba epimedii, fructus lycii and maca extract according to a specific ratio, and three pairs of key mass ratios of zinc / selenium, L-acetyl carnitine / coenzyme Q10 and natural lycopene / vitamin E are limited for the first time. The composition can synergistically improve sperm quality, reduce oxidative stress and improve serum testosterone level in a multi-target manner, the invention further provides a preparation method of the composition, the uniformity and stability of the composition are ensured through the processes of graded mixing, low-temperature sterilization and the like, and the composition can be used for preparing dietary supplements or health care products for improving oligospermia, asthenozoospermia and abnormal spermatozoospermia.

The invention provides a composition helpful for maintaining prostate health. The composition comprises the following raw materials in parts by weight: 3-5 parts of rape pollen, 0.1-0.5 part of lycopene powder, 0.1-0.2 part of a turmeric ethanol extract, 1-2 parts of a chicory extract, 1-2 parts of a dandelion extract and 1-2 parts of auxiliary materials. The invention also provides a preparation method and application of the composition helpful for maintaining prostate health. According to the invention, the rape pollen, the lycopene powder, the turmeric ethanol extract, the chicory extract and the dandelion extract have a synergistic effect to form a multi-target synergistic effect mechanism of reducing androgen metabolism, preventing inflammatory response and reducing oxidative damage, so that the traditional Chinese medicine composition can prevent and treat prostatic hyperplasia, also has an excellent effect on abacterial prostatitis, and is free of toxic and side effects. And the traditional Chinese medicine composition is safe, efficient and suitable for long-term administration. The invention belongs to the technical field of food and health care product processing.

The invention relates to a recombinant yarrowia lipolytica strain with high yield of astaxanthin as well as a construction method and application thereof. The preparation method comprises the following steps: expressing geranyl geranyl diphosphate synthase CrtE, phytoene synthetase / lycopene cyclase CrtYB, phytoene desaturase CrtI, 3-hydroxy-3-methylglutaryl CoA reductase tHMGR, beta-carotene ketolase CrtW, beta-carotene hydroxylase CrtZ, ATP (adenosine triphosphate) citrate lyase ACL, acetyl-CoA synthase ACS, choline kinase CK and inositol polyphosphate kinase IPK in host bacteria, so as to obtain a recombinant bacterium; the expression cassettes of farnesyl diphosphate synthase ERG20 and isopentenyl pyrophosphate isomerase IDI are obtained. Meanwhile, a photocatalytic material O-g-C3N4 / PEI is added to receive visible light excitation and generate reducing electrons, synthesis of intracellular NADPH is promoted, and then accumulation of astaxanthin is promoted. And continuous fed-batch fermentation is carried out in a 5L fermentation tank, so that the production performance of yarrowia lipolytica is greatly improved, and a foundation is laid for industrial production of high-value terpenoids.

To provide a technique relating to treatment of nausea and / or vomiting.SOLUTION: Administering to a subject in need thereof a therapeutically effective amount of a C50 carotenoids compound. The C50 carotenoids compound is selected from the group consisting of decaprenoxanthin, C50 - astaxanthin, C50 - beta-carotene, C50 - carotene (n = 3) (1616 - diisopentenylphytoene), C50 - zeaxanthin, C50 - caroxanthin, C50 - nostoxanthin, sarsinaxanthin, sarprenoxanthin, acyclic C50 carotenoids bacterioruberin, C50 - canthaxanthin, - lycopene, - phytoene, and combinations thereof. C50 C50.SELECTED DRAWING: Figure 1A

Recombinant microorganisms configured for enhanced production of carotenoids and other compounds and methods of using the recombinant microorganisms for the production of same. The recombinant microorganism can include a modification that decreases phytoene synthase (CrtB) activity, a modification that decreases lycopene-forming phytoene desaturase (CrtI) activity, a modification that decreases lycopene cyclase (CrtY) activity, a modification that decreases beta-carotene hydroxylase (CrtZ) activity, a modification that decreases 2,2′-beta hydroxylase (CrtG) activity, and / or a modification that increases beta-carotene ketolase (CrtW) activity. The recombinant microorganism can be from the genus Novosphingobium, such as Novosphingobium aromaticivorans.

The invention relates to a lycopene and lutein compounded eye-protecting soft capsule and a production process thereof, and discloses a lycopene and lutein compounded eye-protecting soft capsule which improves the bioavailability and stability of fat-soluble components by optimizing the component proportion and the production process and adopting a high-speed emulsification and antioxidant protection treatment technology. The eye-protecting soft capsule and the production process thereof are used for realizing more efficient retina protection and asthenopia relieving. The composition is characterized by comprising the following components in percentage by mass: 2%-10% of lutein ester, 1%-5% of lycopene, 0.5%-3% of zeaxanthin, 10%-25% of DHA algal oil, 0.5%-2% of vitamin E, 20%-40% of medium chain triglyceride, 30%-40% of gelatin, 15%-25% of glycerol and 15%-25% of purified water.

The present disclosure relates essentially to a supplement, the function of which is to enhance immunity, prevent various diseases and assist in therapeutic treatments of various diseases, said supplement includes: 100 mg of lipoic acid, 1 mg of astaxanthin, 10 mg of glutathione, 5 mg of resveratrol, 5 mg of lycopene, 50 mg of epigallocatechin, 300 mg of curcumin, 400 mg of quercetin, 10 mg of coenzyme Q1 and 100 mg of dry açaí extract; formulated with the intention of combining substances that serve functions of assisting in the treatment of various diseases, such as: lipoic acid, which helps in the prevention of liver damage from intoxication, and can be used as a coadjuvant for the treatment of liver cirrhosis due to alcoholism and a coadjuvant for the treatment of diabetes and cataracts.

The application discloses an Escherichia coli genetically engineered strain for producing pyruvic acid derivative compounds, and discloses a method for improving the yield of pyruvic acid derivative compounds in the Escherichia coli, and discloses the application of the Escherichia coli genetically engineered strain in biosynthesis of poly-3-hydroxybutyric acid lactate, 3-hydroxypropionic acid, free fatty acid and lycopene. The application can widely enhance the synthetic metabolic flow with pyruvic acid as a key node by knocking out a leucine response regulator gene, and the modification can effectively strengthen the synthesis capacity of the engineered strain for the four target products, i.e., poly-3-hydroxybutyric acid lactate, 3-hydroxypropionic acid, free fatty acid and lycopene under the condition of various carbon sources. Moreover, the knockout of the gene can specifically promote the lactic acid precursor flux, thereby improving the molar proportion of lactic acid monomers in the product P(3HB-LA). lrp co ​​