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137 results about "Lycopersene" patented technology

Yarrowia lipolytica engineering bacterium for producing astaxanthin in peroxisome compartment and application of Yarrowia lipolytica engineering bacterium

The invention discloses a Yarrowia lipolytica engineering bacterium for producing astaxanthin in a peroxisome compartment and application of the Yarrowia lipolytica engineering bacterium. A complete astaxanthin synthesis path is expressed in host bacteria by recombinant Yarrowia lipolytica; comprising geranyl geranyl diphosphate synthase CrtE, phytoene synthetase / lycopene cyclase CrtYB, phytoene desaturase CrtI, 3-hydroxy-3-methylglutaryl CoA reductase tHMGR, beta-carotene ketolase CrtW and beta-carotene hydroxylase CrtZ, and the enzymes are relocated into peroxisome, so that the enzyme activity of the peroxisome is improved, and the enzyme activity of the peroxisome is improved. The number of expression hemoglobin genes VHb and peroxisome is increased, the surface area of the hemoglobin genes VHb is enlarged, and one or more of enzymes PEX11, PEX19, DNM1 or PHO85 for prolonging the service life of the hemoglobin genes VHb and peroxisome is / are obtained; the astaxanthin production performance of the recombinant strain is verified based on cytoplasm engineering and subcellular organelle compartment engineering, and the astaxanthin production capacity of the yarrowia lipolytica is further improved.
Owner:NANJING TECH UNIV

Application of genetic transformation of populus sibirica and CRISPR / Cas9 gene editing method in plant breeding

The invention relates to an application of a genetic transformation method of populus sibirica and a CRISPR / Cas9 gene editing method in plant breeding, and belongs to the technical field of plant molecular breeding. The method comprises the following steps: (1) soaking an explant in an infection bacterium solution; (2) spreading on a CM1 culture medium; (3) transferring the explant to a CM2 culture medium for 4-5 weeks; (4) transferring the calluses to a CM3 culture medium until adventitious buds are obtained; (5) transferring the callus with the adventitious buds to a CM4 culture medium until cluster buds are obtained; and (6) cutting off clustered seedlings, and inserting the clustered seedlings on a CM5 culture medium. According to the application of the genetic transformation and CRISPR / Cas9 gene editing method of the poplar in plant breeding, a target gene is transferred into a poplar body to obtain a positive plant, meanwhile, a poplar phytoene dehydrogenase (PDS) gene is taken as an example, a poplar mutant of which the PDS gene is knocked out is successfully obtained by applying a CRISPR / Cas9 gene editing technology, and the method is suitable for plant breeding. And a technical support is provided for application of a CRISPR / Cas9 gene editing technology in molecular breeding of the populus sibirica.
Owner:CHINESE ACAD OF FORESTRY

Lycopene cyclase mutant and application thereof

The invention belongs to the technical field of enzyme mutants, and discloses a mutant of lycopene cyclase and application of the mutant, glutamic acid at the 321 site of wild type lycopene cyclase which is derived from arabidopsis and has an amino acid sequence as shown in SEQ ID NO.1 is mutated into lysine, phenylalanine at the 319 site of the wild type lycopene cyclase is mutated into leucine, cysteine at the 323 site of the wild type lycopene cyclase is mutated into alanine, and the mutant of the lycopene cyclase is obtained. 1, and the lycopene cyclase mutant with the amino acid sequence as shown in SEQ ID NO. 2 is obtained. BTS1, CrtB and CrtI are integrated into a saccharomyces cerevisiae BY4741 strain, and a chassis strain ZA1 for stably producing alpha-carotene precursor lycopene is constructed; mutant expression plasmids are constructed, positive clone strains are screened out, and the epsilon-cyclization ability of mutant enzymes is remarkably higher than the beta-cyclization ability; the method comprises the following steps: by taking lycopene as a substrate, constructing an expression vector lipid droplet surrounding protein PET10; gene PAH1, DGA1 and Cat2 related to TAG synthesis and perilipid droplet protein PET10 are constructed on an expression vector and converted into ZA1, and when lycopene is used as a substrate, the efficiency of catalytic production of alpha-carotene is improved.
Owner:DALIAN POLYTECHNIC UNIVERSITY

Yarrowia lipolytica with high yield of beta-carotene as well as construction method and application of yarrowia lipolytica

PendingCN120944727AFungiTransferasesLycopersenePhytoene synthesis
The invention discloses yarrowia lipolytica with high yield of beta-carotene as well as a construction method and application of the yarrowia lipolytica. According to the yarrowia lipolytica engineering bacterium, geranyl diphosphate synthase gene xdGPS, phytoene dehydrogenase gene CarB, phytoene cyclization / phytoene synthesis bifunctional enzyme mutant gene GarRPY27R, acetyl-coenzyme A synthetase mutant gene ACSL641P and pyruvate ferredoxin oxidoreductase gene nifJ are integrated and expressed on a chromosome, and the yarrowia lipolytica engineering bacterium is obtained. Meanwhile, a 3-hydroxy-3-methylglutaryl CoA reductase gene HMGR (3-hydroxy-3-methylglutaryl CoA reductase) derived from the yarrowia lipolytica strain is subjected to overexpression; the yield of the beta-carotene is increased to 13.186 g / L, and the production efficiency is 0.14 g / L / h.
Owner:JIANGNAN UNIV

Traditional Chinese medicine composition and application thereof in preparation of medicine for improving sleep disorder and treating mood disorder or cognitive disorder

PendingCN121466216ANervous disorderDispersion deliveryLycoperseneHypericum perforatum
The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of drugs for improving sleep disorder and treating mood disorder or cognitive disorder. The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by mass: 20-30 parts of lycium ruthenicum, 30-40 parts of nitraria fruit, 15-25 parts of gastrodia elata, 13-25 parts of hyperforin perforatum and 2-6 parts of lycopene. The traditional Chinese medicine composition provided by the invention is prepared from lycium ruthenicum, nitraria fruit, gastrodia elata, hyperforin perforatum and lycopene according to a specific ratio, and the composition can effectively relieve anxiety behaviors of chronic stress bound anxiety model mice through ways of resisting oxidation and inflammation, regulating expression of neurotransmitters and the like, prolong sleep time and improve sleep quality. The learning ability and the memory ability of cognitive impairment mice induced by scopolamine are improved, and the neuron density of brain tissues is increased, so that the neuroprotective effect is achieved.
Owner:TAIYUAN RENRUIDA BIOMEDICAL TECHNOLOGY CO LTD

Sampling equipment for lycopene content detection

The utility model relates to the field of lycopene content detection, in particular to a sampling device for lycopene content detection, which comprises an outer box body, a panel seat, a top sealing cover and an extraction barrel, a placing groove is arranged on the surface of the outer box body, the panel seat is matched with the right side of the placing groove, the extraction barrel is arranged on the inner side of the panel seat, and the top sealing cover is arranged on the top sealing cover. A through hole is formed in the top of the placement groove, and the top sealing cover is slidably connected with the through hole; the extraction barrel is installed on the panel base, through the split structure of the panel base and the outer box body, the extraction barrel can be conveniently taken out for sampling operation, meanwhile, the extraction barrel can be removed for cleaning, the cleaning effect is guaranteed, meanwhile, the crushing structure is installed on the top sealing cover, cleaning operation of a blade is facilitated, secondary use is facilitated, and the extraction barrel can be conveniently taken out for sampling operation. A filter screen and a filter plate are arranged on the inner side of the extraction barrel, solid-liquid separation operation after tomatoes are smashed is facilitated, liquid enters a bottom liquid storage cavity, solids are retained on the surface of the filter plate, cleaning is conducted by removing the filter plate, and convenience is improved.
Owner:XINJIANG TOMATORED BIO-TECH CO LTD

Lycopene composition and emulsion preparation thereof

The invention relates to a lycopene composition and an emulsion preparation thereof. The lycopene composition is prepared from lutein, beta-carotene, all-trans lycopene, 9-cis lycopene, 11-cis lycopene and 13-cis lycopene. The emulsion preparation also comprises an emulsifier, a co-emulsifier, an antioxidant and water, has good solubility in water, can obtain solutions with chromaticity of L30-35, a35-40 and b25-30, and is concentrated in tone value range and stable in tone coloring.
Owner:CHENGUANG BIOTECH GRP CO LTD

Preparation for improving male erectile function and sperm quality and preparation process

The invention discloses a preparation for improving male erectile function and sperm quality. The health-care food is characterized by being prepared from the following raw materials in parts by weight: 30-50 parts of herba epimedii extract, 20-40 parts of herba cistanche extract, 15-30 parts of fructus lycii extract, 18-35 parts of semen cuscutae extract, 10-25 parts of herba cynomorii extract, 8-20 parts of maca powder, 6-18 parts of raspberry extract, 0.5-2 parts of lycopene, 1-3 parts of L-carnitine and 0.3-1 part of vitamin B family (vitamin B1, vitamin B2, vitamin B6 and vitamin B12 are mixed according to the mass ratio of 1: 1: 2: 0.5). The herba epimedii extract is selected as a main component, the content of icariin is regulated to be not lower than 60%, the high-content icariin can more effectively promote sex hormone secretion, enhance sexual desire and improve erectile function, the total content of echinacoside and verbascoside in the herba cistanche extract is not lower than 45%, and the herba epimedii extract and the herba cistanche extract have the effect of promoting sex hormone secretion, enhancing sexual desire and improving erectile function. The two components have the effects of tonifying kidney yang and benefiting essence and blood, and can enhance kidney functions.
Owner:TIANJIN ZHENBIAN BIANSE ENTERPRISE MANAGEMENT CO LTD

Blending device for lycopene production ingredients

The utility model relates to the technical field of lycopene production, in particular to a lycopene production ingredient blending device which comprises a blending box, a heating sleeve barrel is fixedly connected to the upper end of the blending box, a blending tank is fixedly connected to the interior of the heating sleeve barrel, a lifting air cylinder is fixedly connected to the position, located on the right side of the heating sleeve barrel, of the upper end of the blending box, and a connecting plate is fixedly connected to the output end of the lifting air cylinder; through the use of the stirring rod and the filter barrel I, ingredients are fully stirred and uniformly mixed at different depths, the stirring efficiency is improved, and meanwhile, the scraping blades fully clean and scrape the inner wall of the ingredient tank along with the rotation of the stirring blades, so that the adhesion of the materials is prevented, the mixing effect is improved, the heat transfer is promoted, and blended mixed liquid flows into the filter barrel II; the first filtering barrel rotates to drive the second filtering barrel to rotate synchronously, centrifugal force is generated to conduct double filtration on mixed liquid, the filtering precision is high, and the product quality of lycopene is effectively improved.
Owner:XINJIANG TOMATORED BIO-TECH CO LTD

Mutagenic chlorella capable of realizing high yield of phytoene and application of mutagenic chlorella

The invention provides mutagenic chlorella capable of realizing high yield of phytoene and application of the mutagenic chlorella, and belongs to the technical field of chlorella. The mutagenic algal strain SZU-C49 of the mutagenic chlorella pyrenoidosa is preserved in the Guangdong Microbial Culture Collection Center, the preservation number is GDMCC No: 66780, the preservation time is July 30, 2025, and the preservation address is the 5th floor, No. 59 building, No. 100 Courtyard, Xianlie Middle Road, Guangzhou. The algal strain is obtained by carrying out chemical mutagenesis and screening on a mutagenic chlorella wild type common chlorella original strain. The mutagenic chlorella disclosed by the invention is cultured for 72 hours under an optimized culture condition, the content of phytoene in cells of the strain reaches 25799 mg / g (dry weight) and is more than 100 times that of an original strain, and the mutagenic chlorella can be widely applied to the fields of functional foods, health-care products, cosmetics, medicines and the like.
Owner:SHENZHEN UNIV

Yarrowia lipolytica engineering bacterium for producing esterified astaxanthin as well as construction method and application thereof

The invention discloses yarrowia lipolytica engineering bacteria for producing esterified astaxanthin as well as a construction method and application of the yarrowia lipolytica engineering bacteria. According to the invention, acyltransferase ScDGAT2-1 from fission vibrio is integrated in a genome of a yarrowia lipolytica engineering strain DN20, diacylglycerol acyltransferase DGA1 and phosphatidic acid phosphatase PAH1 are knocked out, and the corn oil lipoprotein Oleosin and the acyltransferase ScDGAT2-1 from fission vibrio are subjected to fusion expression, so that the yarrowia lipolytica engineering strain DN20 is obtained. According to the present invention, the Yarrowia lipolytica engineering bacterium capable of producing esterified astaxanthin at a high yield is constructed by using SBT06-005 as a raw material and integrating beta-carotene hydroxylase CrtZ, endogenous truncated 3-hydroxy3-methylglutaryl coenzyme A reductase tHMG1, phytoene synthase CarRP and beta-isopropyl malate dehydrogenase LEU2, and the SBT06-005 can produce 166.6 mg / L esterified astaxanthin and 1097.0 mg / L total astaxanthin in a 5L fermentation tank.
Owner:EAST CHINA UNIV OF SCI & TECH

Composition for improving sexual life and / or prostate symptoms and preparation method thereof

The invention discloses a composition for improving sexual life and / or prostate symptoms and a preparation method thereof. The composition is prepared from the following components in parts by weight: 30 to 50 parts of algal polysaccharides, 15 to 25 parts of phospholipid, 8 to 12 parts of euphausia superba oil, 8 to 12 parts of magnesium oxide, 8 to 12 parts of lycopene, 2 to 4 parts of zinc gluconate, 1 to 3 parts of radix ginseng extract, 0.8 to 1.2 parts of flos sophorae immaturus extract, 0.8 to 1.2 parts of fructus rubi extract, 0.8 to 1.2 parts of mulberry fruit extract, 0.8 to 1.2 parts of fructus lycii extract and 0.8 to 1.2 parts of sodium selenite. By limiting the raw materials and the dosage, under the combined action of the raw materials, the prepared composition can improve erectile, ejaculation and anterior lacrimal gland symptoms, can improve the quality of sexual life, and has no side effect on the body.
Owner:HAINAN LEYUN BIOTECHNOLOGY CO LTD

Recombinant saccharomyces cerevisiae for producing beta-carotene and application thereof

PendingCN121427898AFungiMicroorganism based processesLycoperseneCarotene metabolism
The invention provides recombinant saccharomyces cerevisiae for producing beta-carotene and application of the recombinant saccharomyces cerevisiae, and belongs to the field of genetic engineering. According to the invention, a beta-carotene metabolic pathway is constructed in saccharomyces cerevisiae, screening is carried out on a key gene lycopene cyclase gene in the metabolic pathway, and site-directed mutagenesis is carried out on lycopene cyclase derived from Rhizomucor circinelloides f. Lusitanius, so that a mutant is constructed. According to the invention, the constructed mutant is expressed in saccharomyces cerevisiae, so that the titer of beta-carotene is remarkably improved.
Owner:HEILONGJIANG NHU BIOTECH CO LTD +1

Packaging box (lycopene oleoresin soft capsules)

ActiveCN309830713SBiotechnologyLycopersene
1. Name of the product in this design: Packaging Box (Lycopene Oleoresin Soft Capsules). 2. Application of this design: This design relates to a packaging box for lycopene oleoresin soft capsules. 3. The key design features of this product are the combination of pattern and color. 4. The image or photograph that best illustrates the design's key features: the front view. 5. The design for which protection is sought includes color.
Owner:XINJIANG XIYU GUOBAO BIOTECHNOLOGY CO LTD

Iron-free deoxygen composition

The invention provides an iron-free oxygen removal composition. The iron-free deoxidizing composition comprises ascorbyl palmitate, a natural antioxidant, activated carbon, adsorption silica gel, a 4A molecular sieve and water. The natural antioxidant comprises lycopene, ginger, orange and lemon powder. In the composition, the ratio of ascorbyl palmitate to lycopene powder to other components (activated carbon, adsorption silica gel with the water activity of 0.47-0.60 and a 4A molecular sieve) is maintained to be 3.2: 1.1: 1.4. The iron-free deoxidant composition has enhanced oxygen uptake capability, and can remove oxygen, moisture and peculiar smell in the package at the same time. The iron-free deoxidant composition is environment-friendly, and can prolong the shelf life of medicines, foods and nutritional health-care products.
Owner:马尼什·贾恩

Genes slsgr1 and sl lcy-b1 for bidirectional regulation of lycopene content in plants and application thereof

ActiveCN119351460BBiotechnologyLycopersene
The application provides genes SlSGR1 and SlLCY-B1 for bidirectional regulation of lycopene content in plants and application thereof, relates to the technical field of biotechnology, and discloses application of SlSGR1 protein or related biological materials of the SlSGR1 protein and SlLCY-B1 protein or related biological materials of the SlLCY-B1 protein in regulation of lycopene content in plants. By gene editing, the SlSGR1 protein and the SlLCY-B1 protein are inactivated, the activity of SlPSY1 is improved to promote synthesis, and SlLCY-B1 is inactivated to stop metabolism. SlPSY1 and SlLCY1 interact through PDS, ZDS and CRTISO to improve the content of lycopene. Experiments prove that SlPSY1 and SlLCY-B1 are expressed in fruits, and gene editing does not affect the functions of other genes in the family in stems, leaves and other parts. A new approach for establishing efficient, safe and high-lycopene germplasm is provided.
Owner:XINJIANG PRODION & CONSTR CORPS NO 6 DIV AGRI SCI INST

Efficient and stable lycopene isomerization method

The invention discloses an efficient and stable lycopene isomerization method which comprises the following steps: dissolving trans-lycopene in an organic solvent, adding a transition metal-based catalyst, adding a catalytic medium (namely confined water molecules) in a reaction system, keeping out of light, heating and stirring, thereby efficiently catalyzing lycopene isomerization. According to the method disclosed by the invention, the isomerization efficiency of cis-lycopene can be improved to 82.2%, which is far higher than 37.6% of thermal isomerization in the prior art; and under the process conditions, the lycopene has a higher retention rate of 90.3%, and later application of the lycopene is facilitated.
Owner:CHINA PHARM UNIV

Lycopene-loaded targeted nano NK cell exosome gel and application thereof

The invention relates to the technical field of biological medicine, and particularly discloses a targeted nano NK cell exosome gel loaded with lycopene and application thereof, the targeted nano NK cell exosome gel loaded with lycopene is prepared from the following components in percentage by mass: 0.1 to 1 weight percent of lycopene oleoresin, 0.5 to 5 weight percent of NK cell exosome, 60 to 80 weight percent of gel system and the balance of ultrapure water; the lycopene oleoresin is prepared by the following steps: firstly, adding a eutectic solvent into a tomato fermentation extracting solution, carrying out ultrasonic extraction on lycopene, and then uniformly mixing the lycopene, sophorolipid and vegetable oil. According to the application, the NK cell exosome and the lycopene are organically matched, the NK cell exosome directly acts on the local part of the cervix uteri through the NK cell, and meanwhile, the lycopene can repair the damaged cervix uteri cell and restore the damaged cervix uteri cell to a normal structure, so that the purposes of removing viruses and preventing and treating cervical cancer are achieved.
Owner:URUMQI TIANJI HONGYA BIOTECHNOLOGY CO LTD

Packaging box (Prostate Health Lycopene)

1. Name of the product in this design: Packaging Box (Prostate Health Lycopene). 2. Purpose of this design: For packaging health products. 3. The key design features of this product are the combination of shape and color. 4. The picture or photo that best illustrates the key points of the design: main view. 5. The design for which protection is sought includes color.
Owner:ZHEJIANG CONBA PHARM SALES CO LTD

Green environment-friendly polyurethane finish paint as well as preparation method and application thereof

The invention relates to the field of polyurethane coatings, in particular to a green and environment-friendly polyurethane finish paint as well as a preparation method and application thereof. The polyurethane finish paint comprises a component A and a component B, the component A comprises a fish gelatin-lycopene dispersion, a branched polyether / polyester dispersion and a filler, and the component B is aliphatic polyisocyanate resin. According to the invention, fish gelatin-lycopene dispersoid is introduced into polyurethane finish paint, so that fish gelatin-lycopene is uniformly embedded into a net structure of aliphatic polyisocyanate resin, the three-dimensional net structure of a polymer is prolonged, and the emission of volatile organic compounds is reduced; the hardness, the stability, the glossiness and the fullness of the polyurethane finish paint are improved.
Owner:QINGYUAN HUAWAN MATERIALS RES INST CO LTD

Composition for improving prostate health based on plant synergistic interaction as well as preparation method and application of composition

The invention discloses a composition for improving prostate health based on plant synergistic interaction and a preparation method and application thereof.The composition is prepared from, by weight, 10-20 parts of saw palmetto extract, 5-15 parts of lycopene microcapsules, 15-30 parts of pumpkin seed powder, 5-10 parts of green tea extract, 3-8 parts of curcumin microcapsules and 15-40 parts of auxiliary materials; the auxiliary materials comprise a filling agent, a disintegrating agent and a lubricating agent, the filling agent accounts for 50-70% of the total weight of the auxiliary materials, the disintegrating agent accounts for 20-35% of the total weight of the auxiliary materials, and the lubricating agent accounts for 5-15% of the total weight of the auxiliary materials. According to the present invention, the plant components in the specific ratio are subjected to precise compatibility, and the differentiation microcapsule technology and the process optimization are combined so as to achieve the hormone regulation-anti-oxidation-anti-inflammatory synergistic effect, and the effect is far better than the effect of the single component; the bioavailability of raw material components can be effectively improved, the problem of absorption of fat-soluble components is solved, and an efficient and safe innovative scheme is provided for prostate health maintenance.
Owner:WEIHAI BAIHE BIOTECH

Recombinant yarrowia lipolytica strain for producing astaxanthin based on fusion protein method and application of recombinant yarrowia lipolytica strain

The invention discloses a Yarrowia lipolytica engineering bacterium for producing astaxanthin based on a fusion protein method and application of the Yarrowia lipolytica engineering bacterium. A complete astaxanthin synthesis path is expressed in host bacteria by recombinant Yarrowia lipolytica; comprising geranyl geranyl diphosphate synthase CrtE, phytoene synthetase / lycopene cyclase CrtYB, phytoene desaturase CrtI, 3-hydroxy-3-methylglutaryl CoA reductase tHMGR, beta-carotene ketoalcohol enzyme CrtW and beta-carotene hydroxylase CrtZ, and astaxanthin synthesis key enzymes CrtW and CrtZ are subjected to fusion expression by using a short peptide or Linker, so that the astaxanthin is obtained. Meanwhile, the expression of hemoglobin VHb from vitreoscilla is increased; the astaxanthin production performance of the recombinant strain is verified on the basis of protein engineering and fermentation engineering, and the astaxanthin production capacity of the yarrowia lipolytica is further improved.
Owner:NANJING TECH UNIV +1

A composition for alleviating, repairing testicular damage caused by heat stress and use thereof

The application belongs to the technical field of medicine, and particularly relates to a composition for alleviating and repairing testicular damage caused by heat stress and application thereof. The composition for alleviating and repairing testicular damage caused by heat stress comprises the following raw materials: lycopene inclusion compound, ginsenoside Re, modified chitosan nanoparticles and a solvent. The amount of the modified chitosan nanoparticles is 10-15 wt% of the ginsenoside Re. The application innovatively designs a combination formula with lycopene and ginsenoside Re as the core. Both of the two main effective components in the formula are natural plant or traditional Chinese medicine extract, which effectively avoids the conflict between the medicinal properties of traditional Chinese medicines and has good biological safety. The composition can significantly repair the testicular damage caused by heat stress and accelerate the recovery after heat stress damage.
Owner:NANJING BIODE CO LTD

Application of astragaloside in regulating development of parthenogenetic activated embryos

The invention belongs to the technical field of biology, and particularly relates to application of astragaloside in regulation of parthenogenetic activation embryo development. According to the method disclosed by the invention, the maturation rate of the oocytes can be obviously improved by adding substances such as astragaloside into the sheep oocyte in-vitro maturation liquid. The preparation method comprises the following steps: firstly, respectively adding lycopene, astragaloside, isoliquiritigenin, forsythin and baicalein into an oocyte maturation solution, and screening out the optimal dosage of each additive according to the first polar body discharge rate, the cleavage rate and the blastocyst rate; and finally, adding an additive combination into the oocyte maturation liquid according to the screened optimal dosage, detecting the first polar body discharge rate, the cleavage rate and the blastocyst rate to determine an optimal composition, and detecting the levels of ROS, GSH, mitochondrial membrane potential, oxidative stress and apoptosis related genes of the optimal composition to further determine the application effect of the composition.
Owner:SHIHEZI UNIVERSITY

Liriodendron chinense LCYE gene and expression protein and application thereof

The application discloses a Liriodendron LCYE gene, an expression protein thereof and application, and relates to the technical field of plant genetic engineering.The Liriodendron LCYE gene disclosed by the application comprises LcLCYE gene, or / and LtLCYE gene, or / and variant gene LcLCYE-alpha, or / and variant gene LtLCYE-alpha; and the nucleotide sequences of the genes correspond to SEQ ID NO.1, 3, 5 and 7 respectively.The results of the examples of the application show that the Liriodendron LCYE homologous protein has traditional LCYE enzyme activity, and also has LCYB enzyme activity for catalyzing lycopene to form gamma-carotene and beta-carotene; and the C-terminal structure of the Liriodendron LCYE homologous protein is necessary for the LCYE enzyme activity function, but does not affect the LCYB enzyme activity function.
Owner:NANJING FORESTRY UNIV

Pharmaceutical composition for delaying senescence and resisting oxidation

The invention discloses a pharmaceutical composition for delaying senescence and resisting oxidation, and belongs to the technical field of biological medicine and health food. The composition comprises vitamin A, beta-carotene, vitamin complex B, vitamin C, vitamin D, vitamin E, vitamin k, macroelements including calcium, phosphorus, potassium and magnesium, microelements including zinc, selenium, iron, chromium, copper, molybdenum, iodine, fluorine and manganese, traditional Chinese medicines including ginseng, astragalus membranaceus, fructus lycii and radix polygoni multiflori preparata, and condition essential nutrient nucleic acid. The bioactive components comprise lycopene, tea polyphenol, taurine, lutein, lutein fat, zeaxanthin, chlorophyll and the like; is mainly suitable for middle-aged and elderly people; the composition eliminates multiple factors causing aging from multiple systems, multiple links and multiple targets, can significantly delay aging, has health-care and tonifying effects such as oxidation resistance, and can improve the life quality of middle-aged and elderly people while delaying aging; the composition has no incompatibility, and does not generate any toxic or side effect after being taken for a long time.
Owner:BEIJING GUANWUZHOU BIOSCIENCE INSTITUTION (CN)

A preparation process of adding lycopene in balsamic vinegar

The application relates to the technical field of vinegar production equipment, and discloses a preparation process for adding lycopene into balsamic vinegar, which solves the problem that the current production and processing steps are relatively complicated because lycopene is added after the vinegar is filled, and the preparation process comprises a base, a packaging bottle conveying mechanism is arranged on the top of the base, a simultaneous feeding mechanism is arranged on the top of the packaging bottle conveying mechanism, and a collecting mechanism is arranged on the simultaneous feeding mechanism; the application is characterized in that the cooperation between the lifting plate, the limiting rod and the U-shaped frame facilitates the longitudinal movement of the lifting plate, the balsamic vinegar feeding pipe and the lycopene feeding pipe can be simultaneously inserted into two adjacent packaging bottles to add balsamic vinegar and lycopene respectively, the packaging bottle located below the lycopene feeding pipe has been added with balsamic vinegar, the simultaneous addition of balsamic vinegar and lycopene can be realized along with the conveying of the packaging bottles, and therefore the production and processing speed is improved.
Owner:ZHENJIANG DANHE VINEGAR

Anti-aging oral liquid and preparation method thereof

The invention provides anti-aging oral liquid and a preparation method thereof, and belongs to the technical field of oral liquid. Ginseng, turmeric, astragalus membranaceus and ginger are subjected to bidirectional fermentation through a ganoderma lucidum seed solution, a product is subjected to alcohol precipitation to obtain traditional Chinese medicine polysaccharide, and active components are obtained through freeze drying; the preparation method comprises the following steps: extracting cod skin to obtain a collagen peptide-copper compound, mixing the collagen peptide-copper compound with egg yolk protein for enzymolysis to obtain an egg yolk protein-collagen peptide-copper composition, adding the egg yolk protein-collagen peptide-copper composition into water, embedding the egg yolk protein-collagen peptide-copper composition with active components to obtain an active component embedding solution, adding traditional Chinese medicine polysaccharide, resveratrol, taurine and lycopene, homogenizing and filtering to obtain the anti-aging oral liquid. The anti-aging oral liquid prepared by the invention is simple in preparation method and wide in raw material source, and the prepared oral liquid has excellent anti-oxidation, anti-aging and anti-cancer effects, is relatively low in cost, is easy to realize industrial production, and has a wide application prospect.
Owner:JOY (GUANGDONG) PHARMACEUTICAL BIOTECHNOLOGY CO LTD

A composition containing mesenchymal stem cells and its use in the preparation of products with anti-inflammatory action

The application belongs to the technical field of stem cells, and specifically discloses a mesenchymal stem cell-containing composition and application of the mesenchymal stem cell-containing composition in preparation of a product with an anti-inflammatory effect. The lycopene and oleuropein are added to an activation culture medium. On one hand, the lycopene and the oleuropein can protect the biological activity of the mesenchymal stem cells, improve the immune regulation function of the mesenchymal stem cells, further promote the repair of tissues, improve the proliferation capacity of the mesenchymal stem cells, and promote the generation and secretion of active factors with an anti-inflammatory effect in the mesenchymal stem cells and effectively protect the activity of the active factors. On the other hand, the synergistic effect of the lycopene and the oleuropein can more effectively reduce the tissue damage caused by oxidative stress and inflammation, and significantly improve the anti-inflammatory effect of the composition.
Owner:深圳惠善生物科技有限公司