223 results about "Anxiety" patented technology

The invention discloses a sleep aiding method and system based on brain wave data, and the method comprises the steps: synchronously collecting brain waves, electrocardiosignals, environmental noise and user voice data through a flexible electrode array, constructing a multi-mode causal graph, and dynamically recognizing the type of a noise source (electromagnetic interference or psychological noise); the method comprises the following steps of: generating a target antagonistic intervention signal (such as reverse sound wave counteracting electromagnetic noise and binaural rhythm relieving psychological pressure) according to the target antagonistic intervention signal, generating dynamically adaptive light pulse and tactile vibration parameters in combination with a psychological-physiological collaborative model, and synchronously outputting sound, light and tactile intervention signals through a multi-modal actuator. Through causal reasoning and multi-sensory cooperative regulation and control technologies, accurate inhibition of noise interference and personalized induction of the sleep state are realized, the sleep time is remarkably shortened, the deep sleep duration is prolonged, and the method is particularly suitable for complex noise environments and anxiety-related insomnia scenes.

The invention discloses a method and a system for intelligently pushing a live program by a set top box, and relates to the technical field of intelligent pushing. The method comprises the following steps: registering a remote controller input event capturer on an operating system layer to collect and classify user operation events, extracting behavior characteristic data and carrying out standardized preprocessing; a behavior state data set and a situation data set are formed, a remote control behavior anxiety index anx is constructed through the behavior state data set, behavior state evaluation is carried out, the regularity of user operation is evaluated, the influence of the current environment of a user on an operation behavior is analyzed in combination with a situation adaptation matching index cfs, and then an intervention activation comprehensive index sis is calculated. The method is used for judging whether pushing of the pacifying type live program is triggered or not. According to historical statistics, a double intervention threshold is set, a dynamic response type push decision is carried out on the emotional state of the user, identification of potential anxiety behaviors and content intervention control are effectively achieved, and user experience and content adaptability are improved.

The invention relates to the technical field of data processing and intelligent environment control, in particular to a sleep environment feedback control data processing method based on cognitive behavior therapy logic, which comprises the following steps: a reference model construction step: acquiring a non-contact multi-mode time sequence signal, and reconstructing a reference signal balance curve to construct a target signal manifold model; a simulation flow generation step of converting the preset interference characteristics into signal modulation operators and injecting the signal modulation operators into the model to generate a simulation signal flow; a double-track difference calculation step: executing double-track difference operation to respectively extract residual features representing system deviation and theoretical interference; a similarity judgment and control step: calculating the topological similarity of the residual features in a time-frequency domain, judging a deviation dominant type, generating a corresponding control instruction, and driving an execution mechanism to act; according to the method, psychological anxiety and environmental discomfort are effectively distinguished by using a double-track differential mechanism, and accurate attribution analysis of sleep interference sources is realized.

The invention provides a pet behavior data acquisition and emotion monitoring method and an integrated system. The method comprises the following steps: firstly, collecting heart rate, body temperature, environment temperature and humidity and videos, unifying a time base by matching short-distance wireless timestamp broadcasting with local time service, performing face mask, foreground separation and skeleton key point extraction on the videos by an end side, and only uploading structural features including key point coordinates and foreground area ratios; time lag is obtained through normalized cross-correlation of the skeleton key point speed sequence and the heart rate sequence, phase alignment is completed, and a first feature sequence is obtained; frequency domain analysis is conducted on the tail trajectory, the auricle pitch angle and the first feature are connected in series to form a second feature sequence, the second feature sequence is input into a cross-modal attention sequential network, and continuous coordinates and discrete categories such as relaxation, excitation and anxiety are output in a combined mode; a deviation degree is calculated based on an individualized rhythm baseline, and a graded alarm is output when the threshold is exceeded and the standard is continuously reached, so that pet emotion monitoring which is privacy-friendly, reliable in alignment and explainable is realized.

The invention relates to the technical field of psychological intervention adjustment, in particular to a dynamic structured self-adaptive training method which is applied to a training framework comprising an acquisition terminal, a processing terminal and an execution terminal. The acquisition terminal is used for acquiring a physiological signal, a behavior signal and an environment context of an individual, the processing terminal fuses the information and calculates an anxiety index and an uncertainty probability value, and when the uncertainty probability value is lower than a preset threshold value, an initial task graph is constructed according to a target task and the environment context. The initial task graph is subjected to structure and parameter updating through a preset rule generator in combination with a reward function and an anxiety index, an individualized task graph is generated, cross-age migration is further carried out based on physiological and behavior signals, an execution graph bound with an execution terminal is obtained, and the execution terminal carries out intervention according to the execution graph. The problem that an existing training method is difficult to give consideration to behavior complexity and psychological bearing capacity is solved, and training individuation and stability are improved.

A method, computer-readable media, and system associated with psychiatric and physiologic monitoring of a patient having PTSD or anxiety-related mental health conditions are provided. For example, data associated with a survey or questionnaire that was provided to a patient is received. A score may be determined from the data associated with the survey or questionnaire. A time-series is formed using heart-rate measurements detected by a sensor. Fractal properties, such as a Hurst exponent, may be calculated for the time-series. The score may be contextually matched to a set of reference scores. Further, the contextual matching may be used to determine a range of normative HRV values for determining whether a value associated with the patient is within the range. If the value associated with the patient is not within the range, a notification may be provided.

The invention discloses a cabin mental health adjustment method and device and electronic equipment, and the method comprises the steps: obtaining original data sorted based on a time sequence from multiple dimensions after a vehicle is started; extracting data features of the original data of the multiple dimensions to obtain a data feature vector corresponding to each modal; inputting the data feature vectors into a pre-trained multi-modal time sequence fusion model according to a time sequence to obtain a first recognition result; the first recognition result is used for representing the emotion category and / or emotion intensity of the person in the vehicle; determining at least one target adjustment strategy from an adjustment strategy library based on the first identification result and the attribute information of the person in the vehicle; and adjusting the equipment in the cabin based on the target adjustment strategy. The psychological state of the person in the vehicle can be adjusted in time when negative emotions such as anxiety and fatigue of the driver are found, the driving safety is improved, and the user experience is optimized. According to the invention, user health management is promoted, and vehicle intelligence can be enhanced.

The invention belongs to the technical field of nutritional compositions, and particularly relates to a composition, a preparation method thereof and application of the composition in protecting brain health. The composition provided by the invention is prepared from docosahexaenoic acid, 3-sialic acid lactose and phosphatidylserine. The composition is clear in sleep improvement effect, can effectively solve the problem of sleep maintenance caused by sleep deprivation, has the effects of protecting neural functions, improving memory and relieving anxiety from multiple dimensions, and can repair brain tissue damage and protect brain health. Based on the composition, products for assisting in improving memory, preventing and treating insomnia and anxiety, regulating neurodevelopmental disorders, protecting brain health and improving concentration can be developed, the health requirements of different people are comprehensively met, and the application value is high.

The invention relates to the technical field of nerve regulation and control, and discloses a brain wave frequency modulation instrument which comprises a wearing shell and two groups of brain wave frequency modulation optimization modules which are integrally mounted at two ends of the wearing shell and are configured to acquire brain wave signals of a user in real time, according to the brain wave frequency modulation instrument, the defect of single-frequency static stimulation of traditional equipment is overcome, personalized brain wave regulation and control are achieved through the AI algorithm, and the brain wave frequency modulation instrument has the advantages that the brain wave frequency modulation instrument is simple in structure, convenient to use and high in practicability. Frequency conversion guide field signals can be dynamically matched with the brain wave state of a user, and the central control module can adaptively regulate and control multi-module combination. According to the equipment, brain wave optimization, purification and energizing are synchronously carried out, a closed-loop feedback system improves regulation and control accuracy, the wearable design is portable and easy to use, brain wave disorder can be accurately improved, anxiety and fatigue can be relieved, and multi-directional guarantee is provided for physical and psychological health.

A Peripheral Nerve Stimulation (PNS) system and method are disclosed. The system includes a headset with ear hooks and electrodes for placement on the mastoid processes. A stimulation device connected to the headset via lead wires delivers a pulsed electrical current to the electrodes. The device communicates with a computing device equipped with a mobile application that controls the stimulation characteristics. The mobile application allows users to adjust settings, monitor progress, and access treatment sessions. The system also includes snap ports for electrode attachment, self-adhesive hydrogel electrodes, and current control mechanisms using a digital potentiometer and waveform generator. The method includes pre- and post-session anxiety rating, personalized treatment based on user inputs, and tracking of physiological biomarkers. The application supports multiple operating systems, secure cloud data storage, and enables data sharing with healthcare providers. The invention provides a comprehensive, customizable, safe solution for managing anxiety and insomnia.

1. The name of the design product: pacifier (ear type). 2. The use of the design product: to help babies relieve anxiety and meet the needs of sucking. 3. The design points of the design product: in the shape of the product structure. 4. The picture or photo that best indicates the design points: perspective drawing.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of drugs for improving sleep disorder and treating mood disorder or cognitive disorder. The invention provides a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by mass: 20-30 parts of lycium ruthenicum, 30-40 parts of nitraria fruit, 15-25 parts of gastrodia elata, 13-25 parts of hyperforin perforatum and 2-6 parts of lycopene. The traditional Chinese medicine composition provided by the invention is prepared from lycium ruthenicum, nitraria fruit, gastrodia elata, hyperforin perforatum and lycopene according to a specific ratio, and the composition can effectively relieve anxiety behaviors of chronic stress bound anxiety model mice through ways of resisting oxidation and inflammation, regulating expression of neurotransmitters and the like, prolong sleep time and improve sleep quality. The learning ability and the memory ability of cognitive impairment mice induced by scopolamine are improved, and the neuron density of brain tissues is increased, so that the neuroprotective effect is achieved.

The invention belongs to the field of traditional Chinese medicines, and provides application of a valerian extract in preparation of a medicine for preventing and treating climacteric syndrome. Pharmacological experiments show that the valerian extract has a regulation effect on a hypothalamic-pituitary-neuroendocrine system, and has important significance in regulating postmenopausal endocrine conditions of middle-aged and old women and improving anxiety, insomnia, dysphoria and other climacteric symptoms related to FSH (follicle stimulating hormone) and LH (luteinizing hormone). In addition, the valerian extract has a good regulation effect on secretion of related sex hormones and hypothalamus neurotransmitters of climacteric rats, and has a certain correction effect on the central monoamine neurotransmitter disorder state of the climacteric rats. The traditional Chinese medicine composition can improve clinical symptoms of climacteric syndrome.

The invention discloses a lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 for transforming curcumin to produce tetrahydrocurcumin to relieve nervous anxiety, and belongs to the technical field of microorganisms. The lactobacillus delbrueckii subsp. Bulgaricus CCFM1520 screened by the invention has the capability of converting curcumin, and can utilize curcumin and generate tetrahydrocurcumin. The invention further provides a synbiotic preparation prepared from the lactobacillus gasseri CCFM1481 and curcumin, the synbiotic preparation can be used as an anti-fatigue functional medicine, the individual behavioral memory level can be improved, the imbalance of body neurotransmitters (DA, 5-HT and NE) can be slowed down, the expression of body neuroprotection related genes (BDNF, TrkB, DRD1 and TH) can be improved, and the synbiotic preparation has a huge application prospect.

The utility model discloses a pediatric nursing sputum aspiration auxiliary device, including inlet portion, flaring portion and silicone rubber layer, the inside of the inlet portion is through and is square tube structure, the inside of the flaring portion is through and is round tube structure, the inlet portion and the flaring portion are mutually connected and through, the silicone rubber layer is sleeved on the inlet portion. The tongue of a child is pressed through the inlet part according with the ergonomic design, displacement is not prone to occurring, the inlet part is sleeved with the silicon rubber layer, a child patient can conduct oral cavity operation such as chewing and biting, and therefore anxiety and impatience caused by the fact that the oral cavity of the child patient cannot move are avoided; therefore, the emotion of the child patient can be well relieved, the comfort of the child patient is effectively improved, a medical worker can insert a sputum suction pipe into the oral cavity to suck sputum after the sputum suction pipe sequentially penetrates through the flaring part and the inlet part, and reliability is high.

The invention relates to a novel compound as a 5-HT2A receptor inverse agonist, and a preparation method and a pharmaceutical composition thereof. The invention also relates to application of the compound or the pharmaceutical composition in preparation of drugs for treating 5-HT2A receptor related diseases, wherein the diseases comprise non-motor symptoms caused by Parkinson's disease, such as delusional disorder, hallusion, depression, anxiety, cognitive disorder and sleep disorder; dementia-related mental disorders; major depression; or negative symptoms of schizophrenia and the like.

The present invention relates to a pyridino aryl or heteroaryl derivative having a Kappa receptor antagonistic activity. In particular, the present invention relates to a compound represented by general formula (IV) or general formula (VII), a stereoisomer thereof, a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable salt of the stereoisomer. The invention also relates to a pharmaceutical composition containing the compound, a preparation method of the pharmaceutical composition, and a treatment method and application of diseases related to the antagonistic activity of the Kappa receptor, such as depression, depression with pleasant sensation deficiency, bipolar affective disorder, anxiety and other mental diseases. Wherein each substituent in the general formula (IV) or the general formula (VII) is as defined in the specification.

The application relates to a facial expression recognition-based method and system for evaluating anxiety of children in dental treatment. The method comprises the following steps: acquiring a three-dimensional facial point cloud sequence, a two-dimensional micro-expression texture image sequence and a bone conduction audio signal sequence in the process of dental treatment of children; performing point cloud cleaning and three-dimensional reference grid reconstruction on the three-dimensional facial point cloud sequence to obtain a geometric base grid sequence, and performing texture mapping to obtain a texture-mapped three-dimensional face grid sequence; extracting an acoustic feature sequence, a facial action unit intensity sequence and a facial micro-motion intensity sequence; normalizing the data before treatment as a calibration baseline to obtain a relative action unit intensity sequence and a relative micro-motion intensity sequence; performing multi-modal fusion to obtain a continuous emotional disturbance index; grading to obtain a dynamic Frankel behavior scale result, calculating an individualized fear survey score, and fusing to obtain a dental treatment anxiety index of children. The method can realize dynamic evaluation of dental treatment anxiety of children and improve the accuracy of anxiety evaluation.

The invention discloses an AI psychological counseling method and system, and the method comprises the steps: collecting the physiological signal data, behavior signal data, text signal data and individual attribute data of an individual, and the individual attribute data at least comprises the gender; extracting physiological features from the physiological signal data, extracting behavior features from the behavior signal data, extracting text features from the text signal data, and determining the individual attribute data based on the physiological features, the behavior features and the text features in combination with the individual attribute data. Respectively calculating a depression risk value, an anxiety risk value, a pressure load risk value and a crisis warning risk value to form a four-dimensional theme risk vector; calculating a total risk value according to the four-dimensional theme risk vector; and comparing the total risk value with a preset threshold sequence, and determining individual risk levels including a health level, a mild level, a moderate level, a severe level and a crisis level. According to the method and the system, the technical problem of large single-mode error in the traditional psychological service is solved.

The present invention relates to a compound, of the formula:Wherein variables are as defined in the specification and pharmaceutical composition comprising thereof, more specifically compound of the present invention is thiophenyl and pyrrolyl azepine compound; The compound is serotonin receptor (5-HT2c) ligand, useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT2c) is desired (e.g. addiction, anxiety, depression, obesity, and others).

The application discloses a polypeptide GRN-E and application thereof in preparation of a medicine or preparation for perimenopausal emotional disorder. It is found for the first time that a GRN-E fragment (a C-terminal domain of PGRN, an amino acid sequence is SEQ ID NO. 1 in a sequence listing) can pass through a blood-brain barrier and has a unique effect in relieving perimenopausal anxiety and depression. As a key functional fragment, the GRN-E has a more concentrated effect on a central nervous system and can effectively avoid off-target effects of a full-length protein. The polypeptide GRN-E of the application can be applied to preparation of a medicine or preparation for perimenopausal emotional disorder as an innovative treatment target and a novel biological preparation and has a high clinical conversion value.

The invention discloses an AI-assisted insomnia typing and personalized intervention system, which belongs to the field of medical artificial intelligence, and comprises a multi-modal data acquisition module used for synchronously acquiring psychological assessment data, physiological index data, clinical diagnosis data and dynamic behavior data of an insomnia patient, the psychological assessment data comprises a DCPR semi-structured interview text, a PSSS scale score, a PSQI scale score, an AIS scale score, an ESS scale score, an HAMA scale score and an HAMD scale score; according to the method, the DCPR semi-structured interview text, the EEG / PSG physiological signal and the wearable device behavior data are subjected to time-space synchronization integration, the semantic features of the psychological text are analyzed through BiLSTM + attention mechanism, and precise classification of healthy anxiety type, persistent psychosomatic type and other psychosomatic syndrome subtypes is realized in combination with hierarchical clustering and random forest algorithms, so that the accuracy of psychosomatic syndrome subtypes is improved, and the accuracy of psychosomatic syndrome subtypes is improved. The limitation of traditional ICSD-3 / DSM-5 single-dimension diagnosis is broken through, and the clinical significance of subtype distinguishing is improved.

This invention provides an intelligent delivery room care system integrating multimodal environmental control based on sound, light, and temperature, belonging to the field of medical care equipment technology. By integrating multimodal environmental sensing and control capabilities based on sound, light, and temperature, combined with real-time analysis of the mother's physiological and behavioral states, this invention achieves intelligent, personalized, and contextualized management of the delivery room environment. Its main advantages include: significantly reducing the mother's anxiety and pain perception during childbirth, increasing the success rate of natural childbirth; reducing the burden of environmental control operations on medical staff, improving nursing efficiency; supporting adaptive environmental switching across multiple stages and scenarios, meeting the needs of the entire cycle from labor to postpartum recovery; ensuring the dignity of the mother and data security through non-invasive monitoring and privacy protection design; and a modular system design that facilitates integration with existing hospital information systems (HIS) and intelligent ward platforms.

A display device for assessing and analyzing social media addiction, anxiety, and depression, comprising a mobile base (1), characterized in that the top of the mobile base (1) is fixedly connected to a fixing column (2), a lifting groove (3) is formed on the top of the fixing column (2), a cylinder (4) is fixedly connected in the lifting groove (3), the output end of the cylinder (4) is fixedly connected to a lifting column (5), the front end of the lifting column (5) is fixedly connected to a fixing seat (6), a rotary rod (7) is passed through the fixing seat (6) and rotatably connected to it, the two sides of the outer circumference of the rotary rod (7) are fixedly connected to connecting blocks (8), the left end of the rotary rod (7) is fixedly connected to a worm gear (9), the front end of the lifting column (5) is fixedly connected to a connecting plate (20), and the top of the connecting plate (20) is fixedly connected to a first motor (10).the output end of the first motor (10) is fixedly connected to a worm shaft (11), the front ends of the two connecting blocks (8) are fixedly connected to a display (12), the four corners of the mobile base (1) are fixedly connected to fixing cylinders (13), extension grooves (14) are formed on the undersides of the four fixing cylinders (13), second motors (15) are fixedly connected in the extension grooves (14), the output ends of the second motors (15) are fixedly connected to threaded spindles (16), the outer circumferences of the threaded spindles (16) are threaded to lifting blocks (17), and the outer circumferences of the lifting blocks (17) are fixedly connected to extension cylinders (18).

The application discloses an application of Campanula medium in treatment of perimenopausal depression, and a method is as follows: Campanula medium is added into 10 times of distilled water in weight, decocted for 1 h and filtered, residues are added with 8 times of distilled water, and then decocted for 1 h and filtered, and filtrates are combined, and concentrated into 1 g / mL of medicinal liquid according to medicinal material, so that Campanula medium medicinal liquid is obtained. According to the experimental result, Campanula medium can improve the depression and anxiety behavior of PMD model mice. Campanula medium can improve the hippocampus tissue morphology and structure of the PMD model mice, increase the neuron Nissl body abundance of the hippocampus, promote the ER-BDNF-TrkB path, improve the monoamine neurotransmitter level, correct the HPA axis hyperactivity, and thus improve the depression behavior.

This invention provides a head positioning device for neurosurgical testing, belonging to the technical field of neurosurgical medical equipment. It includes a housing, with a first electric slide rail nested at the front end of the housing. A head fixation mechanism is installed at the output end of the first electric slide rail. A second electric slide rail is laterally installed at the front end of the housing. The head fixation mechanism is used to position and fix the patient's head. A noise reduction mechanism is installed at the front end of the housing, positioned below the head fixation mechanism. This noise reduction mechanism is used to fix the ears on both sides of the patient's head and reduce noise to alleviate the patient's anxiety. This invention solves the problems of physical sound insulation and psychological stress by fixing the patient's ears on both sides through the noise reduction mechanism. The bite fixation mechanism allows the patient's mouth to bite down on the bite device and supports the patient's jaw, preventing slight head movement and effectively improving the stability of the test data.

This invention relates to the fields of animal behavior, animal welfare, and mental health conditioning, specifically a music conditioning system and method for pets and laboratory animals. It is a pure PC-based software system, including an audio editing and playback control module, a music library management module, and a music playback module. The output of the audio editing and playback control module is connected to the input of the music playback module, and the music library management module and the audio editing and playback control module have a bidirectional data connection. This invention precisely matches different animals through three parameters: pitch shifting, speed adjustment, and volume adjustment, significantly improving audio compatibility. The effects of emotional stabilization, anxiety relief, and sleep promotion are significantly better than general music. One-click templates are suitable for quick home use. Customizable visual editing is suitable for pet hospitals, laboratory animal centers, and research institutions to establish standardized programs. Waveform graphs, spectrograms, and acoustic spectrograms are displayed synchronously in real time, allowing users to intuitively judge the audio structure. Adjustment accuracy is improved by more than 80%, requiring no professional audio knowledge.

The invention relates to the technical field of sleep regulation and control, and discloses a method for regulating and controlling anxiety insomnia based on LPAG brain region GABAergic neurons, which takes the regulation effect of LPAG on sleep-awakening as an entry point, adopts in-vivo multichannel recording, EEG / EMG polysleep synchronous recording, photoelectrode recording and opto-genetics manipulation on a cell-loop level, and realizes the regulation and control of anxiety insomnia. The system analyzes the effect of the LPAG in sleep-awakening, and proves the regulation effect of the LPAG on anxiety sleep disorder.

This invention relates to the finding that testis development related protein (TDRP; also termed Immuno-moodulin or Imood herein) is a circulatory anxiogenic factor that modulates anxiety-like behaviour in mammalian models through the regulation of the immune system. Methods of treatment of mental disorders, such as anxiety, and TDRP antagonists for use in such methods are provided. Methods of diagnosing or monitoring a mental disorder in an individual by determining levels of TDRP in a sample and methods of screening for compounds that reduce levels of TDRP are provided.

System and Method for Contextual Relationship-Analytics A computer-implemented relationship-analytics system ingests time-stamped multimodal communication between a first and second human subject together with public-web persona data and first-subject annotations. Natural-language processing transforms the combined corpus into (i) an attachment-style vector that classifies anxiety-avoidance orientation and (ii) an affinity-language vector that identifies a dominant affection modality. Both vectors are stored in typed fields of an Emotional Digital Fingerprint (EDF) record. Concurrently, a wearable sensor supplies a biosignal, which is digitized to compute a normalized Balance-Load Index (BLI) tagged with a precise time-stamp. The BLI is correlated with co-occurring interaction data within a configurable window; correlation weights update the stored vectors, and a link identifier tying the BLI to its interaction subset is persisted in the EDF. An inference engine reads the updated EDF to output probabilities of long-term compatibility and incompatibility, which are transmitted to a client device for user guidance.