34 results about "Cognitive health" patented technology

The invention discloses an old people cognitive health monitoring system based on virtual reality, and relates to the related technical field of virtual health monitoring technologies. Comprising a multi-modal sensing acquisition module, a virtual reality environment generation module, a cognitive nerve feedback module, a real-time feedback module, a deep learning analysis module, a personalized training plan generation module, a data storage and management module, a remote medical platform and a virtual assistant and coach module. The system can help the elderly to improve the work memory ability through a special work memory training task and a cognitive nerve feedback module, and the elderly can be more efficient during daily life activities by improving the work memory and the attention basic cognitive function aiming at the common attention distraction problem of the elderly, so that the life quality is improved, and the elderly can be helped to take care of the elderly. The cognitive neural feedback module not only pays attention to a cognitive function, but also helps the elderly to better manage emotions by adjusting an emotional network, promotes social interaction, and reduces aloneness and anxiety.

The present invention provides systems and methods for assessing the cognitive health of an individual.

The invention relates to novel bacteria of the species Lactobacillus plantarum and to compositions comprising Lactobacillus plantarum, and methods and uses of said compositions for preventing and / or treating mental illness, symptoms affecting mental health and / or conditions associated with chronic stress, in a mammal. The invention can be applied in restoring, maintaining, and / or promoting mental (including cognitive) health and has potential applications, inter alia, in the area of dietary and food supplements, medicaments and pharmaceuticals.

The invention relates to bacteria of the species Lactobacillus paracasei and / or compositions comprising Lactobacillus paracasei for use in preventing and / or treating a mental illness, a symptom affecting mental health and / or a condition associated with chronic stress, in a mammal. The invention further relates to methods and uses of said bacteria of the species Lactobacillus paracasei and / or compositions. The invention can be applied in restoring, maintaining, and / or promoting mental (including cognitive) health and has potential applications, inter alia, in the area of dietary and food supplements, medicaments and pharmaceuticals.

The invention discloses a brain small vascular disease cognitive disorder assessment method based on gait features and ensemble learning, and relates to the technical field of medical and industrial combination. According to the technical scheme, a wearable device is used for collecting gait data; the collected original data are preprocessed; the cognitive impairment prediction method comprises the following steps: predicting the cognitive degree of a CSVD patient by adopting a plurality of types of models, and establishing a cognitive impairment prediction model by using an integrated learning method based on a voting method and adopting a model selection method based on an elimination method; and evaluating the performance of the model by using the accuracy, the precision, the recall rate, the F1 score and the area under the curve as evaluation indexes. The method has the beneficial effects of accurate, objective and reliable evaluation, early prediction and intervention, high adaptability, simplicity and convenience in operation, capability of providing scientific basis and the like; the popularization and application of the method can provide new thoughts and tools for cognitive impairment evaluation of the CSVD patient, and the cognitive health and life quality of the patient can be improved.

Methods and systems for assessing cognitive function using tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, that one or more cognitive functions of a patient can be assessed based on EEG responses obtained during a cognitive health assessment procedure that includes one or more tests. Such cognitive tests and associated functions include: awake and drowsy, auditory evoked potentials, visual evoked potentials, attention and concentration and information processing, and memory-. The cognitive functions assessments can be based on at least one ERP response type, including any of: N100, P200 and P300 responses or any combination thereof, and comparison to demographic values. Each of the cognitive functions can be scored and compared to repeated assessments overtime.

A method and apparatus for use as part of diagnostic analysis of the psychiatric or neurological health of a patient based on use of a normative database of fMRI data results and cognitive task results for a population of prior patients. Embodiments propose to acquire fMRI data of a particular set of one or more regions of the brain of a patient while the patient is performing a cognitive task, and to record at the same time results of the patient's performance in the cognitive task. A combination of both the cognitive task results and the fMRI data for the brain regions is used to provide an indicator as to a cognitive health status of the patient. More particularly, a normative database of fMRI data results and cognitive task results for a population of patients is used as a reference. This may store results both for healthy patients and pathological patients, to provide a normal and abnormal reference.

The invention discloses a role playing data set construction method based on image enhancement. Relates to the technical field of digital human interaction. Comprising the following steps: acquiring a multi-scene image, and processing by using a multi-modal large language model to generate an image text description; based on the image text description, adopting a retrieval enhancement generation method to generate a figure description of the image main body; generating a memory story between the image content and the person settings by using a DeepSeek large language model based on the image text description and the person settings description; performing multiple rounds of interaction according to the memory story by adopting a double-role playing mechanism, and generating a dialogue data set according to an interaction result; and performing supervised fine tuning on the multi-modal large language model by using the generated dialogue data set. According to the method, a high-quality, personalized and emotion-rich Chinese memory therapy dialogue data set can be constructed, and the method has an important application value for improving artificial intelligence and assisting sentiment and cognitive health of old people.

The invention discloses an elderly cognitive intervention and emotion companion system and method based on a multi-modal large model and dialect adaptation, and the system comprises a multi-modal perception and feature extraction module which is used for collecting multi-modal perception data, processing the multi-modal perception data, and obtaining a multi-modal feature vector flow; the dialect adaptive processing engine module is used for performing dialect acoustic adaptation and emotion semantic adaptation processing on the multi-modal feature vector flow to obtain a semantic vector and an emotion vector; the cognitive state real-time evaluation module is used for performing multi-dimensional linguistic feature extraction on the multi-modal perception data to obtain a cognitive health index of the user; the emotion companion and intervention generation agent module is used for generating a reply text and a multi-mode emotion control label which are adaptive to the user based on the semantic vector, the emotion vector and the cognitive health index; and the multi-modal feedback synthesis module is used for calling a dialect speech synthesis model to generate speech feedback according to the reply text and the multi-modal emotion control label.

This invention relates to the field of cognitive health companionship technology, specifically to a multimodal companionship system for patients with cognitive impairment based on AI technology. The invention receives memory materials from a family member's terminal, constructs an interactive virtual scene, configures guiding questions, records the patient's answers to all guiding questions, sets the initial difficulty level of cognitive training based on an assessed memory recall integrity score, and collects performance data after the patient completes cognitive training tasks to determine if the initial difficulty level needs adjustment. This achieves precise matching of cognitive training difficulty to the patient's current cognitive level. Simultaneously, based on the performance data of cognitive training tasks within a subsequently set training period, a cognitive ability report is generated and compared with historical cognitive ability reports in multiple dimensions to assess the patient's cognitive ability improvement. This reflects the dynamic changes and improvement trajectory of the patient's cognitive ability, effectively improving the targeting and effectiveness of cognitive training.

The present application relates to a kind of cognitive function evaluation and intervention method based on spatial navigation video game, the method includes: obtaining user identity information to establish file;Present three-dimensional virtual environment with first person view, execute route repetition and backtracking task and record direction selection accuracy;According to weighted formula, calculate comprehensive score, compare with preset threshold and output cognitive state discrimination result;According to the real-time performance of user, dynamically adjust path complexity and moving speed, form personalized training;After completing training, evaluate again, generate post-intervention discrimination result;Record and show score change trend and difficulty progression trajectory.The present application integrates screening and intervention, through objective behavior data and adaptive algorithm, can effectively distinguish healthy elderly people and mild cognitive impairment elderly people, and improve cognitive function through personalized training, provides efficient digital solution for elderly cognitive health management.

The invention relates to the use of scyllo-inositol alone or in combination with other active ingredients including the compound N-acetylcysteine or a derivative thereof to support cognitive health in a subject that takes the product or combination product. The compositions, which are inclusive of oral dosage forms such as tablets or capsules, are provided to the subject which is inclusive of humans or other mammals such as dogs or cats or other animals in need of cognitive improvement. The combination product(s) break up amyloid beta aggregates and promote the clearance of amyloid beta fibrils from the glymphatic system as well as the treatment of disease and conditions that are acerbated by free radicals.

The present invention relates to the use of scyllo-inositol alone or in combination with other active ingredients, including the flavone apigenin, to support cognitive health in subjects taking the product or combination product. The present invention relates to compositions comprising scyllo-inositol alone or in combination with other agents, including, but not limited to, flavones or other substances that prevent the upregulation or downregulation of aquaporin 4 channels. The compositions, including oral dosage forms such as tablets or capsules, are provided to subjects, including humans or other mammals such as dogs or cats, or other animals, in need of cognitive improvement. The combination product(s) degrade amyloid-β aggregates and promote the clearance of amyloid-β fibrils from the glymphatic system.

The invention relates to the technical field of data processing, and discloses a mild cognitive impairment detection system based on multi-level data, and the system comprises a terminal device which is used for collecting physiological monitoring data, clinical narrative data and multi-modal test data of a user; the data processing module is used for performing interference identification and information purification on the multi-modal test data to generate a purified cognitive response matrix; the cognitive evaluation module is used for performing cognitive ability decoupling and group benchmarking based on the purified cognitive response matrix and outputting an individual ability level; and the closed-loop management module is used for constructing a longitudinal decline slope model based on a score sequence of individual historical multiple evaluations and carrying out risk early warning and intervention recommendation. According to the method, passive disease screening of cognitive health management is converted into an active, personalized and continuous risk monitoring and intervention process, and a powerful technical tool is provided for delaying cognitive decline.

The invention relates to compositions comprising Lactobacillus plantarum, and methods and uses of said compositions for preventing and / or treating mental illness, symptoms affecting mental health and / or conditions associated with chronic stress, in a mammal. The invention can be applied in restoring, maintaining, and / or promoting mental (including cognitive) health and has potential applications, inter alia, in the area of dietary and food supplements, medicaments and pharmaceuticals.

A method and apparatus are provided for use as part of a diagnostic analysis of a patient's psychiatric or neurological health based on the use of a normative database of fMRI data results and cognitive task results for a population of previous patients. An embodiment proposes to acquire a specific set of fMRI data of one or more regions of the patient's brain while the patient is performing a cognitive task, and at the same time record the results of the patient's performance in the cognitive task. A combination of both the cognitive task results and the fMRI data for the brain regions is used to provide an indication regarding the patient's cognitive health. The normative database of fMRI data results and cognitive task results for a population of patients is used as a reference. It may store results for both healthy and pathological patients to provide normal and abnormal references.

The invention relates to the technical field of biological agents, and discloses a dietary supplement for regulating and controlling neurotransmitters and a preparation method and application of the dietary supplement for regulating and controlling the neurotransmitters. 20 to 60 parts of Omega-3 fatty acid; 5 to 20 parts of magnesium glycinate mitochondria energizing chelate; 0.1 to 0.5 part of a nerve anti-inflammatory peptide LL-37; 10 to 40 parts of a South African drunken solanum extract; 10 to 30 parts of a hericium erinaceus extract; 5 to 20 parts of a rhodiola rosea extract; 5 to 10 parts of a blue lotus-kalon composition; 5 to 20 parts of phosphatidylserine wrapped by nano liposome; and 5 to 20 parts of S-adenosylmethionine. The dietary supplement provided by the invention aims to optimize the functions of neurotransmitters and support emotion stability and cognitive health by combining a plurality of active ingredients from natural sources.

The application discloses a cognitive impairment recognition method based on natural behavior analysis, comprising the following steps: S1, video acquisition and individual separation, real-time acquisition of activity scene video stream, detection of the boundary box of all human bodies, and cross-frame tracking of the detected human body target; S2, natural behavior feature extraction, posture estimation, expression recognition, social interaction analysis and task participation analysis are carried out, and after all the features are normalized, the fixed-length feature vectors are packaged and uploaded to the cloud; S3, mapping of behavior features to cognitive dimensions, the cloud receives the time sequence feature flow of each human body target, calls the pre-trained multi-level mapping model to perform time sequence coding, attention fusion, cognitive dimension decoding, risk identification and suggestion generation; S4, result storage and display, the risk identification result and the suggestion of each time are stored into a time sequence database, and a personal cognitive health atlas is constructed. The application can realize high ecological validity, low cost, high acceptance and fine early screening.

Systems and methods for assessing cognitive function are described that use tracked electrical activity of the brain of the individuals in response to a specific sequence of stimuli in generating data sets, which, for example, can be encapsulated as a data structure. The data sets can include tracked specific response types, at different times and amplitudes, including, but not limited to, event related potential signal components. Brainwave features including, event related potentials, are tracked in relation to both pre-attentive brain responses and consciously controlled attention responses.

Provided herein are systems and methods for a rapid microfluidic in vivo bioassay for evaluating the cognitive health benefits of compounds.

To provide a composition for enhancing, improving, or maintaining cognitive health and / or function.SOLUTION: The present invention provides an oral administration composition for enhancing, improving, or maintaining cognitive health and / or function in a mammal undergoing normal aging cognitive changes, rather than dementia, wherein the composition comprises a water extract of spearmint plant at a dose of 1.6 to 32 mg / kg / day, wherein the water extract comprises about 5 to 15 wt.% of rosmarinic acid, and wherein the extract is administered for a period of at least 90 days.SELECTED DRAWING: Figure 1

The invention discloses a cognitive health management system and method based on cognitive age. The system comprises a cognition evaluation unit used for carrying out cognition evaluation on a user; the data collection unit is used for collecting cognitive score data sets of subjects of different age groups in advance; the norm construction unit is used for constructing norm distribution corresponding to each age group; the age analysis unit is used for analyzing the cognitive score data to calculate a distance value between the cognitive score data and an average value of norm distribution of each age group; the data processing unit is used for carrying out normalization processing on all the distance values so as to output a probability value that the user belongs to each age group; the output unit is used for outputting the age group with the highest probability as the cognitive age of the user; and the feedback unit is used for feeding back personalized cognitive health maintenance and improvement suggestions to the user. The system has the advantages of being economical and practical, easy and convenient to operate, high in user acceptability, high in universality, wide in applicability, scientific, reliable and the like.

A computer-implemented method for determining cognitive health state of a subject. The method includes receiving fNIRS data of the subject. The fNIRS data is acquired using a system operable to perform fNIRS, and the fNIRS data contains information associated with cognitive task related cerebral hemodynamics of the subject. The method further includes processing the fNIRS data to obtain cognitive task related cerebral hemodynamics data, processing the cognitive task related cerebral hemodynamics data using at least a model, and determining, based at least in part on the processing of the cognitive task related cerebral hemodynamics data, the cognitive health state of the subject.

The invention relates to the use of scyllo-inositol alone or in combination with other active ingredients including the flavone apigenin to support cognitive health in a subject that takes the product or combination product. The invention relates to compositions comprising scyllo-inositol alone or in combination with other agents including but not limited to a flavone or other substance that upregulates or prevents the downregulation of aquaporin 4 channels. The compositions, which are inclusive of oral dosage forms such as tablets or capsules, are provided to the subject which is inclusive of humans or other mammals such as dogs or cats or other animals in need of cognitive improvement. The combination product(s) break up amyloid beta aggregates and promote the clearance of amyloid beta fibrils from the glymphatic system.

1. Name of the design product: Swan Lake, cognitive health brain helmet for the elderly. 2. Use of the design product: used for cognitive health management of the elderly in community scenarios. 3. Design points of the design product: in shape. 4. Picture or photo that best indicates the design points: perspective view.

The invention provides a mild cognitive impairment patient screening model training data acquisition method and device and electronic equipment, and relates to the technical field of training data acquisition, and the method comprises the steps: constructing a community natural population cognitive health queue, and obtaining related evaluation data of queue research sample cognition; on the basis of a literature review method, a professional domain knowledge injection method, a domain expert consultation method and a Shap interpretable machine learning method, characteristic variables related to the mild cognitive impairment are screened out from the evaluation data and serve as model training data. The degree of association between the model training data obtained through the method and the mild cognitive impairment is higher, the data source is more real, and the method has more practical application significance.

The invention relates to application of wood frog seeds and extracts thereof in preparation of products for preventing and improving depression, and belongs to the technical field of cognitive health. The product can be a medicine, a health food, a special dietary food or a food for special medical purposes, is particularly suitable for preventing and improving the depression state caused by chronic stress, and can improve depression-like behaviors such as despair behaviors and slow response and regulate related physiological indexes such as 5-HT, TNF-alpha and IL-1beta. The extract is a mixture obtained by hydrolyzing and extracting wood frog seeds or a grease component directly extracted from the wood frog seeds. The application of the wood frog seed and the wood frog seed extract in preventing and improving the depression state provides a new scheme for intervention of depression, and the wood frog seed water extract and the wood frog seed oil not only improve the behavior state of depression, but also play a role in neurotransmitter and immune inflammatory factors; a new natural, safe and effective choice is provided for the field of preventing and improving depression.

This invention relates to the field of cognitive health management technology, specifically a cognitive health management system for the elderly based on virtual reality technology. The system includes an initial login module, a scene acquisition module, a data acquisition module, a cognitive health assessment module, a decision generation module, and a cognitive health management module. The initial login module acquires various selection data from the user. The data acquisition module collects various physical and audio-visual data from the user in real time. The decision generation module generates cognitive health training decisions based on the causes of abnormalities and a preset information database. The cognitive health management module processes the scene training decisions and user feedback to obtain rehabilitation training scenarios and plans that meet the user's needs. This invention addresses the problem of infrequent communication between the elderly and doctors, making it difficult to accurately determine the elderly's cognitive health level based solely on examination data, leading to diagnostic errors.

This invention discloses a cognitive health assessment method based on inspirational texts, comprising: acquiring inspirational texts, wherein the inspirational texts include at least one of dream records, daily inspiration records, and creative notes; extracting complexity features, emotional features, and logical features of the texts; inputting the features into a weighted model to calculate a health score; recording time-series data to generate a trend graph; and triggering an alert when the score continuously declines. This invention is hardware-independent, can be tracked long-term, objectively quantifies cognitive status, and is low-cost and highly compliant.

Extracts of plants of the Lamiaceae family are shown to improve cognitive health and function.