204 results about "Grape seed" patented technology

The invention belongs to the technical field of hair dyes, and particularly relates to a high-grease repairing ammonia-free low-sensitivity essential oil hair dye cream and a preparation method thereof. The ammonia-free low-sensitivity hair dye comprises the following raw materials in percentage by mass: 32-40% of ammonia-free low-sensitivity essential oil, 5-12% of an emulsifier, 5-10% of a thickener, 3-6% of a hair dye, 3-5% of a pH regulator, 1-3% of a humectant, 0.4-0.8% of an antioxidant, 0.1-0.5% of essence, 0.1-0.3% of a chelating agent, 0.05-0.15% of keratin and the balance of water. The ammonia-free low-sensitivity essential oil is a mixture of coconut oil, camellia seed oil, grape seed oil, macadamia nut seed oil, simmondsia chinensis seed oil and squalane. The high-grease repair ammonia-free low-sensitivity essential oil hair dyeing cream provided by the invention can simultaneously meet the effects of lasting color fixation, repair performance and stable storage.

The invention discloses a grape seed source anti-inflammatory peptide, and belongs to the technical field of biological medicine. The amino acid sequence of the anti-inflammatory peptide is selected from any one of WGF, SHFGF, EGPFF, WAPR, SFYRAF, HFAFL, PGRF or FDSF. A BPS-induced RAW 264.7 mouse mononuclear macrophage inflammation model is established, and the eight synthetic peptides are found to significantly reduce the content level of NO in inflammatory cells and have an inhibition effect on secretion of inflammatory factors TNF-alpha and IL-6. A qRT-PCR (quantitative reverse transcription-polymerase chain reaction) experiment shows that the synthetic peptide can inhibit expression of mRNA (messenger Ribonucleic Acid) of p65, Tnf alpha, Il6, Il1b and Nos2, and can play an anti-inflammatory role by regulating and controlling an NF-kappa B signal channel. According to the method, the high-activity anti-inflammatory peptide is screened from the wine brewing byproduct grape seeds for the first time, and green and high-value utilization of the grape processing byproduct is realized.

The invention relates to a plant lactobacillus and application thereof in fermentation of a grape seed extract. The strain is named as FBL002, and is preserved in the Guangdong Microbial Culture Collection Center, the preservation address is the 5th floor of the Experimental Building, No.100 Court, Middle Xianlie Road, Xiaoxian District, Guangzhou City, Guangdong Province, and the preservation number is GDMCC No.66015. The tolerance of the plant lactobacillus provided by the invention to active ingredients in the grape seed extract is improved by 34%, and meanwhile, the activity of beta-glucosidase is remarkably improved to 204U / mL. In fermentation application, the strain shows excellent biotransformation performance, the content of total phenols and the content of total flavonoids in the fermented grape seed extract are increased by 45% and 98% respectively compared with an unfermented system, and meanwhile, the scavenging rate of antioxidant activity ABTS free radicals and the scavenging rate of DPPH are remarkably increased to 95%. The strain shows important application value in the fields of functional food development and natural cosmetic raw material production, and an innovative solution is provided for high-value utilization of plant resources.

The invention relates to the technical field of preparation of Pickering emulsion stabilizers, in particular to a protein-polyphenol-polysaccharide ternary covalent complex as well as a preparation method and application thereof. The method comprises the following steps: step 1, preparing a whey protein isolate aqueous solution, completely hydrating the whey protein isolate aqueous solution, compounding a grape seed oligomeric proanthocyanidins aqueous solution and a hydrated protein aqueous solution, adjusting the pH value, and carrying out stirring reaction and dialysis freeze-drying to prepare a protein-polyphenol binary compound; and 2, compounding the binary compound solution with the lycium barbarum polysaccharide solution, uniformly stirring, carrying out Maillard reaction to obtain a ternary compound solution, and freeze-drying to obtain the protein-polyphenol-polysaccharide ternary compound. The invention provides a non-toxic, harmless and pollution-free natural emulsifier and stabilizer, and simultaneously prepares a Chinese wolfberry seed oil Pickering emulsion capable of loading nutritional ingredients and active substances, thereby providing reference for screening research of the natural emulsifier and protection of nutritional ingredients of Chinese wolfberry seed oil, which are easy to photodecompose and oxidize; the problem that the effect of protein serving as a Pickering emulsion stabilizer in the prior art is poor is solved.

The invention belongs to the technical field of hydrogel preparation, and relates to a cartilage-imitating multifunctional drug release hydrogel material and a preparation method thereof. According to the invention, biocompatible high polymer materials such as polyvinyl alcohol, chitosan, grape seed protein, acyl chloride, sulphobetaine methacrylate and lecithin are used as raw materials, a cartilage structure is simulated to prepare the multilayer hydrogel, gelatin and plant polyphenol are mixed as an adhesive to improve the binding capacity with subosseous bones, and a drug is loaded to improve the biological activity. The preparation method of the hydrogel material comprises the five steps of preparation of high-strength anti-swelling precursor hydrogel, introduction of double bonds through surface modification, introduction of a poly SBMA molecular brush through interfacial polymerization, drug loading and preparation of an adhesion layer. The hydrogel has excellent anti-swelling ability, lubricating property, anti-pollution ability, free radical scavenging ability, self-adhesion characteristic, drug controlled release ability and biocompatibility, and has important significance for widening the application of the hydrogel in the field of artificial cartilage.

The invention relates to the technical field of traditional Chinese medicine health-care products, and particularly discloses an earthworm protein peptide composition for improving vascular embolism and a preparation method thereof.The earthworm protein peptide composition is prepared from, by weight, 28-34 parts of earthworm protein peptide, 20-26 parts of active pharmaceutical ingredients, 1-5 parts of ginkgo biloba extract, 12-15 parts of corn oligopeptide powder and 4-8 parts of auxiliary materials; lumbricus protein peptide, active pharmaceutical ingredients, ginkgo biloba extract and corn oligopeptide powder are used as raw materials, a solubilizing component is added in the preparation process, the solubilizing component is prepared by mixing functional extract, nattokinase and tween-80 according to a certain proportion, the functional extract is prepared by coating grape seed extract with hydroxypropyl-beta-cyclodextrin, and the solubilizing component is prepared by mixing the functional extract, the nattokinase and the tween-80 according to a certain proportion. Through the synergistic effect of the components, the antithrombotic effect of the earthworm protein peptide composition is synergistically enhanced.

The invention relates to the technical field of fermented beverages, in particular to a preparation method of a high-activity fruit and vegetable probiotic fermented beverage, which comprises the following steps: adding composite fruit and vegetable juice after enzymolysis, mineral water, xylooligosaccharide, grape seed extract, yeast extract and xanthan gum into a fermentation tank, and stirring until the materials are completely dissolved; then carrying out sterilization treatment by adopting high-temperature instantaneous sterilization; adding probiotic microcapsules into the sterilized mixed liquid, and performing staged temperature-controlled fermentation to obtain fermentation liquid; and performing homogenization treatment on the fermentation liquid, and finally performing vacuum degassing to obtain the high-activity fruit and vegetable probiotic fermented beverage. A composite wall material (sodium alginate-eucheuma powder-gellan gum) of the probiotic microcapsule forms a compact gel network to effectively isolate phenols, organic acids and other antibacterial components in fruits and vegetables, so that the damage of pH fluctuation and temperature change to thalli is resisted.

The invention discloses a formula composition which is prepared from the following components in parts by weight: 100 to 400 parts by weight of grape seed procyanidine, 100 to 300 parts by weight of pomegranate polyphenol, 10 to 100 parts by weight of ergothioneine, 50 to 200 parts by weight of catechin and 100 to 400 parts by weight of astragalus polysaccharide. According to the invention, cell-level anti-aging is taken as a core logic, five active ingredients of grape seed procyanidine, pomegranate polyphenol, ergothioneine, catechin and astragalus polysaccharide are scientifically compounded, a multi-dimensional anti-oxidation defense system is constructed, and multiple effects of scavenging free radicals, repairing cell damage, delaying an aging process and the like can be realized.

The application discloses a grape seed development gene VvPHERES1 and application thereof. The nucleotide sequence of the development gene VvPHERES1 is shown as SEQ ID NO:1. The amino acid sequence of a Type I MADS transcription factor is shown as SEQ ID NO:2. The application clones a grape seed development related gene VvPHERES1 for the first time and studies the gene function. A pCAMBIA2300-VvPHERES1 overexpression vector and a heterologous Micro-Tom tomato plant are constructed. By comparing the changes of seed traits in the overexpression transgenic tomato and the wild type plant, the result shows that the seed quantity in the overexpression transgenic tomato is obviously increased. The application provides a grape seed development related gene, and provides a basis for breeding of seedless grape new varieties.

The utility model discloses an automatic grape seed screening, cleaning and draining integrated device, and relates to the technical field of grape seed processing. The device comprises a workbench, one side of the top of the workbench is fixedly connected with a supporting frame, the top of the supporting frame is provided with a screening assembly, the top of the workbench is fixedly connected with a cleaning assembly, and one side of the top of the workbench is fixedly connected with a draining assembly. The placing frame and the supporting frame are movably connected through the hinge, the inclination angle is controlled through the second electric push rod, after screening is completed, screened grape seeds can be automatically and accurately poured into the cleaning barrel, efficient and automatic connection of the screening link and the cleaning link is achieved, manual intervention is reduced, the pollution risk is reduced, and the working efficiency is improved. Due to the design of an annular pipe and a plurality of nozzles of the cleaning assembly, all-directional spraying cleaning can be conducted on the grape seeds from multiple angles, it is ensured that each grape seed can be fully covered with cleaning liquid, and various pollutants on the surface of the grape seed are effectively removed.

The invention discloses a whitening composition and a preparation method thereof, and belongs to the technical field of functional food, the whitening composition comprises the following components by mass: 20.7-40.7 parts of astaxanthin oil, 45-65 parts of grape seed oil, 5-7 parts of gamma-aminobutyric acid, 4-6 parts of purified water, 1.4-1.8 parts of a grape seed extract (resveratrol), 0.1-0.3 part of a white tomato extract, 0.6-1 part of a polygonatum odoratum extract, and 0.6-0.8 part of a mulberry leaf extract. The whitening composition disclosed by the invention has a good melanin inhibition effect.

The invention discloses antibacterial mouthwash as well as a preparation method and application thereof, and belongs to the technical field of daily chemical products. According to the invention, egg white lysozyme, ferulic acid and grape seed procyanidine are taken as core components, and the mouthwash with an efficient bacteriostatic effect is developed. And the antibacterial rates of streptococcus mutans and porphyromonas gingivalis are 96.88% and 96.30% respectively. Researches show that bacterial biofilms can be destroyed by using the mouthwash, and the biofilm quantity is reduced by 53.7% after the bacterial biofilms are treated for 24 hours; extracellular polysaccharide is inhibited, the content of water-insoluble glucan is reduced by 62.3%, and synthesis of a key cariogenic matrix is hindered; the acid production capacity is regulated and controlled, the pH change of 24-hour culture is only 1.50, and xylitol competitively inhibits glycolysis and cooperates with ferulic acid to block bacterial metabolism. The mouthwash prepared by the invention avoids the problem of enzyme activity inhibition of the ionic surfactant of the traditional mouthwash, takes effect more quickly, and provides a basis for developing natural, safe and efficient functional mouthwash.

The utility model relates to mixed device technical field, and disclose a kind of grape seed oil and vitamin B5 mixing device, including mixing tank body, stirring mechanism, annular plate, radial shear hole, lower opening annular gap.Adopt this structure, stirring mechanism can drive grape seed oil and vitamin B5 in mixing tank body fast stirring mix, and radial tilt arrangement's push flow board can push material to annular plate direction, make material constantly pass radial shear hole on annular plate;Radial shear hole inner diameter is greater than outer diameter, and radial arrangement, fluid passes and will produce high-frequency alternate tangential velocity field, so that fluid occurs stretch, folding and rupture, while material from lower opening annular gap backflow to annular plate inside, form circulation, further speed up mixing efficiency, improve mixing uniformity.

A shampoo granule and a preparation method thereof are provided. The shampoo granule includes the following components in parts by weight: 0.0008-0.0072 parts of a softener, 53-92 parts of a surfactant, 5-25 parts of an adsorbent, 1-10 parts of a moisturizer, 0.5-6 parts of an anti-caking agent, 0.4-5 parts of a hair regulator, 0.1-1 part of a pH regulator, 0.2-1.4 parts of a preservative, 0.1-1 part of a thickener and 0.5-1.5 parts of a fragrance; where the surfactant is a mixture of sodium cocoyl hydroxyethylsulfonate and sodium lauryl glutamate; the softener is a mixture of acanthus kernel oil, avocado fruit oil, grapeseed oil and Lactobacillus / rye flour ferment filtrate. The shampoo granule has excellent gentleness and nourishing cleansing efficacy, and is easy to rinse without residue, which can significantly reduce water consumption during use. The shampoo granule also has advantages of easy transportation and carrying.

The present invention discloses a β-carotene-grape seed extract eye-care preparation for retinal protection, relating to functional health foods. The preparation comprises active components and food-acceptable excipients. In parts by weight, the active components include 1–4 parts lutein, 0.5 –2 parts meso-zeaxanthin, 2 – 6 parts β-carotene, 8 – 25 parts blueberry extract, 5 – 18 parts grape seed extract, 0.2–1 part L-ergothioneine, 0.5–3 parts saffron extract, and 1–5 parts phosphatidylserine. The excipients comprise a filler, disintegrant, binder, and lubricant, with a weight ratio of active components to excipients of 1:1 to 1:4. By combining these eight components at specific ratios, the invention achieves synergistic effects, protects retinal health, and reduces blue-light damage. Dual-phase microencapsulation based on solubility, together with standardized preparation steps, improves stability and utilization efficiency.

The invention provides a composition. The composition is prepared from probiotics, a plant extract and acceptable auxiliary materials according to a specific content ratio. Wherein the probiotics comprise the following components: Weizmannia coagulans AUSA001, Lactobacillus plantarum AUSA002, Bifidobacterium longum subsp. Longum FL006, and the probiotics comprise the following components: the Weizmannia coagulans AUSA001, the Lactobacillus plantarum AUSA002, the Bifidobacterium longum subsp. Longum FL006, the Lactobacillus plantarum AUSA002 and the Bifidobacterium longum subsp. Longum FL006. The plant extract comprises a kudzuvine root extract, a grape seed extract and a turmeric extract. The composition has a synergistic effect, can reduce the content of human intestinal trimethylamine and serum trimethylamine oxide, and is used for prevention or adjuvant therapy of related diseases.

The invention relates to the technical field of grape seed germination methods, and discloses a method for promoting rapid germination of grape seeds, which comprises the following steps: collecting ripe grape fruits, stripping the seeds, washing with clear water for 3-5 times, drying the seeds in the shade, sub-packaging the seeds in centrifugal tubes, preserving at 4 DEG C for later use, placing the seeds in 75% alcohol, oscillating for 5 minutes, washing with sterile water for 3-5 times, and taking out the seeds. Transferring into a 1% sodium hypochlorite solution, oscillating for 30 minutes at the speed of 150r / min, cleaning with sterile water for 3-5 times, cutting off beaks and cotyledon ends of the seeds by using disinfection scissors, simultaneously cutting off the beaks and the cotyledon ends, not performing treatment, immersing the treated seeds into a 150mg / L gibberellin solution, oscillating for 8 hours at the room temperature at the speed of 150r / min, cleaning with sterile water for 3-5 times, absorbing moisture with filter paper, laying the filter paper and sterile gauze in a culture dish, and transplanting the seeds into the culture dish. Adding sterile water until the seeds are wet and free of accumulated water, setting three repetitions for each treatment group, uniformly placing 50 seeds for each repetition, culturing at 25 + / -2 DEG C, alternating illumination / darkness for 12 hours, supplementing water every 3 days, and recording the germination number and the root length.

The invention discloses a cell cellulose composition and application thereof in skin care products, and belongs to the technical field of cellulose preparation. According to the composition, bacterial cellulose, modified amphiphilic grafted cellulose micelles and cellulose nanocrystals are taken as cores, an isoflavone active group is grafted to a cellulose chain through an RAFT polymerization technology, an amphiphilic carrier capable of loading an oil-soluble active matter is formed, grape seed oil, resveratrol and other active ingredients can be loaded, slow release and controlled release are achieved, and the composition has a good application prospect. A bacterial cellulose three-dimensional network and nanocrystals form a protective film on the skin surface, hyaluronic acid can enhance cuticle lipid arrangement and accelerate skin barrier function reconstruction, an isoflavone grafted structure provides ultraviolet protection and anti-inflammatory pathway regulation and control, inflammatory factor release is remarkably inhibited, and the anti-inflammatory effect is achieved. A cellulose nanocrystal and bacterial cellulose composite network is provided to improve the stability of the emulsion, the problem that a traditional product is prone to layering is solved, and the emulsion has the effects of physical barrier, long-acting moisturizing and repairing and is suitable for anti-allergy repairing type skin care products such as essence and masks.

The present invention discloses a composite flocculant, its preparation method, and application. The preparation method comprises: soaking grape seed powder in an alkaline solution, drying, and plasma-treating under pure oxygen conditions to obtain modified grape seeds; soaking the modified grape seeds in an ethanol solution of a silane coupling agent so that the silane coupling agent coats the surface of the modified grape seeds; and drying to obtain amino-functionalized grape seeds; soaking the amino-functionalized grape seeds in the mixed solution and subjecting them to ultrasound-microwave combined treatment to polymerize acrylamide monomers on the surface of the amino-functionalized grape seeds to form polyacrylamide, which is then grafted onto the surface of the amino-functionalized grape seeds to obtain a solid composite flocculant. The composite flocculant of the present invention exhibits excellent suspended solids settling rate and pollutant removal rate when used to treat winery wastewater.

The invention discloses an acidic high-content collagen beverage, which is prepared from the following raw materials in percentage by mass: 30 to 34 percent of collagen peptide, 8 to 12 percent of collagen tripeptide, 0.05 to 0.3 percent of elastin peptide, 0.01 to 0.05 percent of hyaluronic acid, 0.1 to 0.3 percent of grape seed extract, 0.05 to 0.1 percent of xylooligosaccharide, 0.01 to 0.03 percent of sweetening agent, 0.8 to 1.5 percent of acidulant and the balance of water. The pH value of the acidic high-content collagen beverage is less than or equal to 4.6. The acidic high-content collagen beverage disclosed by the invention has the characteristics of excellent taste, high collagen content, acidity, no bad flavor and stable quality.

This invention discloses a natural composite light stabilizer for animal fats and its preparation method. The components and their mass percentages of the natural composite light stabilizer are as follows: rosemary extract: 45%–55%, vitamin E: 20%–25%, grape seed extract: 1%–5%, and olive leaf extract: 24%–25%; the sum of the mass percentages of the components is 100%. The vitamin E, rosemary extract, grape seed extract, and olive leaf extract selected in this invention are all natural and safe raw materials. Under the optimized combination ratio of the four components in this application, the synergistic effect between the components is fully utilized, thereby inhibiting the oxidation rate of edible animal fats under high temperature and light conditions. Its effect is significantly better than commonly used synthetic antioxidants in fats, such as BHA and TBHQ.

The invention relates to the technical field of functional beverages, and discloses a wild jujube and grape seed plant beverage which comprises the following raw materials: purified water, wild jujube (14.28%), spina date seeds, pistachio nuts, a grape seed extract (100mg), sodium alginate, gamma-cyclodextrine, nicotinamide and sucralose. According to the wild jujube and grape seed plant beverage and the preparation method thereof, the wild jujube, the spina date seed and the pistachio nut (sleep-aiding group) are scientifically matched with the grape seed extract and the nicotinamide (beautifying group), so that the double effects of sleep aiding and beautifying are integrated, the market blank is filled up, and all the components have a multi-channel synergistic effect (such as neurotransmitter regulation of sleep-aiding components and synthesis of melatonin), so that the sleep-aiding and beautifying effects of the wild jujube and grape seed plant beverage are achieved. The health-care beverage has the advantages that the efficacy of a single component is improved by 1.5-2 times (the efficacy can be verified through animal experiments or human trial feeding data), and the health-care beverage is mainly prepared from medicinal and edible components, is free of nerve stimulation side effects of chemical components such as melatonin, is free of harmful components and is suitable for long-term drinking.

The invention relates to a lifting and tightening composition for skin as well as a preparation method and application thereof, and belongs to the technical field of cosmetics, the composition is prepared from the following raw materials: compound fermentation liquor, acetylated sodium hyaluronate, glycosylglycerol and a solvent, the compound fermentation liquor comprises a plant compound ingredient, cellulase, a lactobacillus rhamnosus activating solution, a saccharomyces cerevisiae activating solution and a fruit wine yeast activating solution; the plant compound ingredients comprise Chinese wolfberry fruits, litchi pericarp and grape seeds; the composition also comprises a sophora flower extract, a linden flower extract and Arabic gum. The lycium barbarum, the litchi pericarp and the grape seeds are compounded to serve as raw materials and fermented, the technology of first enzymolysis and then fermentation is adopted, the raw materials supplement one another, and the finished product effectively enables skin to have elasticity; in addition, the finished product prepared by the invention also has the effects of resisting aging, replenishing water and preserving moisture; in other words, multiple aspects in the system cooperate with one another, skin laxity is effectively improved, and the skin is lifted and tightened.

This invention discloses a fermented feed for improving the natural antibacterial and antioxidant properties of duck eggs. The fermented feed is prepared through a two-stage fermentation process using a fermentation substrate comprising the following components in parts by weight: 35-60 parts corn, 15-30 parts soybean meal, 5-15 parts wheat bran, 4-10 parts rice bran, 5-9 parts extruded flaxseed, 2-6 parts grape seed meal, 1-4 parts moringa flavonoid powder, 0.5-2.5 parts dicalcium phosphate, 0.5-3 parts limestone powder, 0.1-0.5 parts salt, and 0.1-0.8 parts compound premix. The two-stage fermentation involves first inoculating with Bacillus for aerobic fermentation, followed by inoculation with lactic acid bacteria and the addition of chitosan oligosaccharides for anaerobic fermentation. This invention significantly increases the content of active proteins such as lysozyme and ovotransferrin in duck egg white, enhancing its antibacterial properties and antioxidant capacity, and providing an efficient and economical technical path for the development of highly active duck egg white raw materials.

The application relates to the field of cosmetics, and relates to an anti-aging cosmetic, grape pomace oil and a preparation method thereof. The anti-aging cosmetic comprises grape pomace oil; characteristic components of the grape pomace oil include oleanolic acid, alpha-guaiacwoodene, beta-tocotrienol, beta-sitosterol, campesterol, soybean sapogenol E, ganoderic acid F, ganoderol I and D-erythro-dihydrosphingosine; the total phenol content of the grape pomace oil is greater than or equal to 1 mg / g, the total sterol content of the grape pomace oil is greater than or equal to 26 mg / g, and the total flavonoid content of the grape pomace oil is greater than or equal to 1 mg / g; the grape pomace oil is extracted from grape pomace; the grape pomace is mainly composed of grape skin, grape stem and grape seed. The compounds have excellent antioxidant properties and can improve the anti-aging effect of the anti-aging cosmetic. The compounds are helpful for protecting the skin from oxidative damage and play a positive role in cosmetics. The grape pomace oil maximally retains active components of all parts of the grape pomace.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a novel astragalus membranaceus and poria cocos pill composition and a production process thereof. The raw materials comprise the following components: astragalus membranaceus, codonopsis pilosula, poria cocos, radix angelicae, platycodon grandiflorum, liquorice, red dates, coix seeds, grape seeds, black sesame and spina date seeds. The traditional Chinese medicine composition comprises the following raw material components in parts by mass: 10-20 parts of astragalus membranaceus, 8-15 parts of codonopsis pilosula, 10-18 parts of poria cocos, 5-12 parts of radix angelicae, 6-14 parts of platycodon grandiflorum, 3-8 parts of liquorice, 8-16 parts of red dates, 10-20 parts of coix seeds, 5-10 parts of grape seeds, 8-15 parts of black sesame and 6-12 parts of spina date seeds. The invention has the following beneficial effects: shape optimization: 3-5mm pills are prepared, the pill is convenient to take, the dosage is easy to control, and compared with decoction and powder, the pill is more convenient to store and carry; the production process is simple, parameters of each step are clear, large-scale production can be realized by adopting conventional traditional Chinese medicine processing equipment, and the production cost is relatively low; and the quality is stable: by strictly controlling raw material moisture, crushing granularity, mixing uniformity and finished product drying parameters, the finished product is stable in quality and long in validity period.

The present invention relates to a melanin precursor composition, a preparation method and an application thereof. The melanin precursor composition comprises the following raw materials for preparation by weight: 14-20 parts of soybeans, 12-18 parts of black truffles, 10-15 parts of grape seeds, 8-12 parts of cocoa beans, 6-10 parts of Chinese gallnuts, and 6-10 parts of holly leaves. The melanin precursor composition is prepared from the above raw materials through pretreatment, primary extraction, complex protease hydrolysis, secondary extraction, Saccharomyces cerevisiae fermentation, and enzymatic reaction. The melanin precursor composition can effectively solve the problems existing in the existing hair dyes, such as low dyeing efficiency, poor dyeing effect, and poor dyeing durability, while ensuring safety and good use experience, and has good market prospects.

The invention discloses a depression-relieving and liver-soothing pill and a preparation method thereof, and belongs to the technical field of Chinese patent medicines. The depression-relieving and liver-soothing pill comprises the following active ingredients: vinegar-processed rhizoma cyperi, grape seeds, bran-fried rhizoma atractylodis macrocephalae, poria cocos, hawthorn, pericarpium citri reticulatae, ginger-fried fructus gardeniae, vinegar-processed rhizoma corydalis, fructus aurantii, betel nuts, liquorice, medicated leaven, pericarpium citri reticulatae viride, radix aucklandiae, fructus amomi and radix linderae. According to the invention, the alcohol extract of the grape seeds is added into the traditional depression-relieving and liver-soothing pill, so that the depression-relieving and liver-soothing pill is obviously improved in the effect of enhancing the activity of pepsin and pancreatin, and a better instant curative effect can be obtained when the depression-relieving and liver-soothing pill is used for treating chest and hypochondrium fullness, inappetence and other symptoms.

The anthocyanin source grape seed candy is a tabletted candy prepared from peel residues obtained after wine grape fermentation is finished through the working procedures of airing, rolling, blowing, careful selection, cleaning, drying, ultraviolet sterilization, multiple times of smashing, honey adding, stirring, tabletting, vacuum packaging and the like. Only grape seeds and honey are used as raw materials, no preservative or additive is added, and a pure natural product is not subjected to chemical treatment.