A production process of a
water soluble ginkgo leaf extract comprises the following steps of pulverizing
ginkgo leaf, and extracting with
ethanol for 2-4 times to obtain concentrated solution I; diluting with
purified water, filtering to obtain medicinal liquid II, washing the residue with
purified water for several times, filtering the supernatant to obtain medicinal liquid III, mixing with the medicinal liquid II, diluting with water, and filtering to obtain clear medicinal liquid IV; adsorbing with macroporous adsorptive resin, pre-washing with
purified water or
ethanol, and eluting with
ethanol to obtain medicinal liquid V; concentrating the medicinal liquid V to obtain
alcohol-free
concentrated extract VI; extracting the
concentrated extract VI with ethanol for 2-4 times, filtering, and concentrating the filtrate to obtain
concentrated extract VII; or alternatively completely dissolving conventional
ginkgo leaf extract in ethanol, recovering ethanol to obtain concentrated extract, extracting with ethanol for 2-4 times, filtering, and concentrating the filtrate to obtain concentrated extract VII; and extracting the concentrated extract VII with purified water for 2-4 times, cooling the extractive solution, filtering, concentrating, and
drying to obtain the
water soluble ginkgo leaf extract. The inventive production process has the advantages of simple process, stable product quality, and good economic benefit.