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Ginger and long pepper composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer

A composition, ginger technology, applied in the direction of drug combination, antineoplastic drugs, pharmaceutical formulations, etc., to achieve the effect of inhibiting tumors, reducing the rate of vomiting, and increasing the inhibitory effect

Inactive Publication Date: 2011-08-31
QINGDAO UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no Chinese patent medicine that can reduce the side effect of vomiting and enhance the effect of anti-cancer radiotherapy and chemotherapy

Method used

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  • Ginger and long pepper composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer
  • Ginger and long pepper composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer
  • Ginger and long pepper composition as well as preparation method and application thereof in preparation of toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0042] The first step: preparation of various extracts

[0043] (1) Preparation of concentrated extract of ginger and Piperumba decoction

[0044] According to the compatibility ratio of 1:1 or 1-4:1, take ginger and Piperumba, soak in 10 times the amount of distilled water, soak for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate and medicinal residue Add 6 times more distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brownish yellow powder, which is ginger Piper Piper decoction concentrated extract.

[0045] (2) preparation of gingerol

[0046] Cut the ginger into thin slices, dry it naturally, grind it into powder with a high-speed universal pulverizer, pass through a 30-mesh sieve, put the sifted fine powde...

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Abstract

The invention relates to a natural medicine composition as well as a preparation method and application thereof in preparation of a toxicity reducing and efficacy enhancing medicament in radiotherapy and chemotherapy of cancer. The natural medicine composition is prepared from a ginger and long pepper decorated concentrated extract, gingerol, a long pepper ethanol extract and piperine at a ratio of (2-8):(1-4):(2-4):(3-9). The composition has an extremely good efficacy for vomiting and other side effects caused by radiotherapy and chemotherapy of cancer, and simultaneously plays a role in suppression of tumors.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of gingerol, Pipera ethanol extract and piperine The preparation method of the invention and the use of the natural medicine composition in the preparation of medicines for reducing the side effect of vomiting caused by cancer radiotherapy and chemotherapy and having a synergistic effect on cancer treatment. Background technique [0002] Cancer has become a major killer facing human beings, and its mortality rate is second only to cardiovascular diseases, and it is increasing year by year. There are 1.8 million malignant tumor patients in my country every year, and 2 / 3 of them receive radiotherapy and chemotherapy. Although there is a certain curative effect, most patients will experience side effects to varying degrees after radiotherapy and chemotherapy. The most common side effects are nausea and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K36/67A61P35/00A61K31/12A61K31/4525
Inventor 石振艳岳旺王继波刘娜
Owner QINGDAO UNIV
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