Pistacia chinensis bunge and gingerol containing composition for chemotherapy for cancer with capabilities of decreasing toxicity and synergism

Abstract

The invention discloses a pistacia chinensis bunge and gingerol containing composition for chemotherapy for cancer with the capabilities of decreasing toxicity and synergism and belongs to the technical field of medicaments. The pistacia chinensis bunge and gingerol containing composition is prepared from the following components including a pistacia chinensis bunge extract and a gingerol component with the weight ratio of (10-25):(1-3), and the following medicinal raw materials including pachyma cocos, fructus amomi, fructus evodiae, cuscuta, all-grasses of desertliving cistanche, pinellia ternate, perilla, dried tangerine peels, trogopterus dung and blackberrylily rhizome can also be added. According to the pistacia chinensis bunge and gingerol containing composition, with the pistacia chinensis bunge extract and the gingerol component as the core raw materials, the natural medicament composition is prepared with matching of other auxiliary components; residues in the extraction process of gingerol are kept for replacing a part of the auxiliary components, can serve as both the auxiliary component and the effective component, are capable of effectively inhibiting emesis caused by chemotherapy for the cancer and have the actions of synergism and decreasing toxicity for treatment of the cancer; after adding the traditional Chinese medicine components, the traditional Chinese medicine components take synergistic effect to the pistacia chinensis bunge extract and the gingerol, have the action of preventing and treating the emesis caused by the chemotherapy for the cancer, also have certain therapeutic effect for the cancer and are capable of inhibiting tumors.

Description

Technical field [0001] The invention relates to a natural medicinal composition, in particular to an attenuating and synergistic composition for cancer chemotherapy containing kaimu and gingerol. The natural medicinal composition is prepared and used for the preparation of reducing vomiting caused by cancer chemotherapy Side effects and synergistic effect on cancer treatment. Background technique [0002] Cancer has become a major human disease. Although chemotherapy has certain effects, most patients will experience severe nausea and vomiting after chemotherapy, which can cause dehydration, electrolyte disorders, malnutrition, and metabolic acidosis, etc., which can easily lead to physical health in patients. The nutritional imbalance and collapse of the patient’s body seriously affect the quality of life of the patient, and sometimes even have to interrupt treatment. Commonly used antiemetics, such as histamine, acetylcholine, dopamine receptor antagonists, hormones and cannab...

AI Technical Summary

Problems solved by technology

[0002] Cancer has become a major human disease. Although chemotherapy has a certain effect, most patients will experience severe nausea and vomiting after chemotherapy, which can cause dehydration, electrolyte imbalance, malnutrition, and metabolic acidosis, etc., which can easily lead to physical symptoms in patients. The nutritional imbalance and the collapse of the patient's body seriously affect the quality of life of the patient, and sometimes the treatment has to be interrupted

Commonly used antiemetics such as histamine, acetylcholine, dopamine receptor antagonists, hormones, and cannabinoids have poor curative effect on post-chemotherapy vomiting, strong toxic and side effects, and are greatly limited in application

Novel antiemetic drugs such as NK1 receptor antagonists and 5-HT3 receptor antagonists have good antiemetic effects, but are expensive and have a narrow range of application. Therefore, the development of natural low-toxic anticancer synergistic drugs is urgently needed

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