The invention relates to a formula and a preparation method of compound desert
cistanche granules, the compound desert
cistanche granules are prepared by adding
flavor on the basis of Qingzheng dialectical
record yang-warming soup, the raw materials comprise desert
cistanche, bighead atractylodes
rhizome, monkshood, Chinese angelica,
cynomorium songaricum, fried
semen raphani and perillaseed, and the total weight of a single bag is 7g. The production process comprises the key steps of pretreatment of medicinal materials, independent first decoction of
radix aconiti carmichaeli for detoxification, extraction of
semen raphani and perillaseed volatile oil, inclusion of beta-
cyclodextrin, combined decoction and concentration of all the medicinal materials, dry
granulation and the like, and the technical effects that granules are instantly dissolved within 45 + / -5 seconds and the transfer rate of crude drugs is 91.2% are achieved by optimizing the proportion of auxiliary materials and process parameters. The quality of the finished product meets the requirements of
Chinese Pharmacopoeia, the content of
aconitine is less than or equal to 0.02%, the total number of microbial limit
aerobic bacteria is less than or equal to 100 CFU / g, the problems that a traditional compound
cistanche deserticola preparation is slow in
dissolution speed, unstable in
toxicity control and non-standard in production process are solved, and the method is suitable for large-scale industrial production.