38 results about "Large intestine" patented technology

The present invention relates to an artificial digestive tract tissue for training in endoscopic submucosal dissection (ESD) and a method for manufacturing the same. Specifically, the invention relates to an artificial digestive tract tissue configured to mimic the mucosal layer, submucosal layer, and muscle layer constituting the human digestive tract tissue in a multilayer structure, such that swelling occurs upon liquid injection and a color change occurs due to changes in salt concentration, and to a casting and curing-based hydrogel molding process for manufacturing the same. According to the present invention, the problems associated with existing animal tissue-based ESD training simulators can be resolved, repeated use is possible, and training tailored to the structural characteristics of specific organs (stomach, large intestine, small intestine, etc.) is possible.

Aspects of the present disclosure relate to compositions and methods for treating one or more inflammatory bowel diseases ("IBD"), such as ulcerative colitis ("UC") and / or Crohn's disease. Some embodiments relate to a pharmaceutical dosage form comprising a core comprising an inhibitor of a protease (e.g., a bacterial protease) and a controlled release coating applied to an outer surface of the core. In some cases, the protease inhibitor is a gligliptin or a pharmaceutically acceptable salt thereof. In some cases, the controlled release coating is configured to release the protease inhibitor in the large intestine (e.g., colon) and / or small intestine of a subject administered the pharmaceutical dosage form. Some embodiments relate to methods of treating one or more IBDs comprising delivering a therapeutically effective amount of an inhibitor of a protease (e.g., bacterial protease) to the large intestine (e.g., colon) and / or the small intestine of a subject.

[Problem] To provide a method or program for obtaining a virtual large intestine cleansing image that can remove residual matter from large intestine imaging data captured without the use of laxatives. [Solution] The method includes: an image input step, in which a captured image representing a part of a patient's large intestine is input; and a virtual large intestine cleansing step, in which a virtual large intestine cleansing image representing a part of the patient's large intestine with residual matter removed from the captured image is obtained. The invention also provides a program for causing a computer to execute the above method for obtaining virtual large intestine cleansing images.

Disclosed are a system and method for analyzing a stool image, which derive the state of the large intestine of a user by analyzing a stool image by using a pre-trained deep learning model. The system for analyzing a stool image may include an input unit configured to receive stool images of a user, a data set generation unit configured to generate a data set by grouping the stool images in chronological order, an analysis unit configured to derive information on a stool state of the user or information on a state of the large intestine of the user by analyzing the data set, and an output unit configured to output the information on the stool state or the information on the state of the large intestine. The endoscopic activity of ulcerative colitis can be predicted from a camera image of stool even without performing a colonoscopy.

1. Name of the designed product: packing box (white water intestine). 2. Use of the designed product: for packing sausage. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: perspective view.

The application discloses an LNG ship liquid cargo tank based on a large intestine structure, wherein a spherical main screen wall comprises a main screen wall body and a heat insulation material layer. A wall surface of the main screen wall body is in a large intestine wall structure, and an outer surface of the main screen wall body is coated with the heat insulation material layer. A hemispherical secondary screen wall covers an upper hemisphere of the spherical main screen wall. A pipe tower vertically penetrates from a top of the hemispherical secondary screen wall to an inside of the spherical main screen wall. The spherical main screen wall is embedded in a groove of a circular opening of a ship body. A drip receiving tray is connected with a bottom of the groove. An equator edge of the hemispherical secondary screen wall is connected with the ship body at the circular opening of the groove through a skirt support structure. A hatch cover covers a part of the hemispherical secondary screen wall exposed to the ship body. The application improves a deformation capacity of the liquid cargo tank, i.e. an expansion and contraction deformation capacity caused by temperature change, and effectively reduces thermal stress. The inner screen wall structure in the bionic large intestine wall has the effects of reducing a liquid free surface area, slowing down liquid sloshing and improving ship body stability, and enhances safety of the LNG ship liquid cargo tank.

The invention relates to a vibrating fecal evacuator. More particularly, the invention relates to a vibrating fecal evacuator that abrades and evacuates the mass in the intestine in a controlled manner and without causing side effects, especially for individuals suffering from constipation due to an excessively hardened fecal mass in the large intestine that blocks normal defecation.

The present invention relates to a combination comprising vitamin B2 and Lactobacillus rhamnosus and its use for improving gut health in animals and humans. It was found that a combination of vitamin B2 and Lactobacillus rhamnosus, when delivered to the large intestine, increases the abundance of beneficial Verrucomicrobia, Akkermansiaceae and Akkermansia bacteria in the intestinal tract.

1. The name of the design product: large intestine packaging bag (full garden). 2. The use of the design product: for packaging products. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view. 5. The design product is a flat product, omitting the left view, right view, top view, and bottom view.

The application discloses a kind of multi-organ intelligent segmentation method and device based on Eff-Unet-SE network, belong to medical image processing technical field.The method includes: obtaining MRI image dataset and label text data, and it is preprocessed;The image dataset after the pre-processing is carried out data division and data enhancement;Eff-Unet-SE network is constructed, and it is trained, verified and tested using the image dataset and label text data, to obtain optimal network;The MRI image data to be segmented is input to the optimal network, to obtain segmentation result.The application is analyzed to medical MRI image, on the basis of U type network model, in combination with the Efficient and SE network module of deep learning, can accurately separate out large intestine, small intestine and stomach, improve the reliability of segmentation result, also improve segmentation efficiency, greatly reduce the work burden of doctor.

Provided is an endoscopy assistance device, wherein object detection means detects an object included in an endoscopic image obtained by imaging the inside of the large intestine by means of an endoscopic camera. A position information acquisition means acquires position information indicating the position of the endoscopic camera in the large intestine. A display control means displays a schematic diagram having a shape imitating the intestinal tract of the large intestine and, when a predetermined instruction is given upon detection of the object, the display control means adds a mark to the position of the schematic diagram corresponding to the position of the endoscopic camera indicated by the position information. The endoscopy assistance device can be used to assist decision-making by a user conducting an endoscopy.

The application belongs to the technical field of food processing equipment, and relates to an automatic large intestine water filtering machine, which comprises a rack, a squeezing cylinder, a driving assembly and a squeezing telescopic cylinder. A working panel is arranged on the rack. The working panel is sequentially divided into a material receiving area, a water filtering area and a discharging area along the horizontal direction. The squeezing cylinder is in sliding contact with the working panel. The driving assembly is connected with the squeezing cylinder and drives the squeezing cylinder to reciprocally slide between the material receiving area, the water filtering area and the discharging area. A filtering opening and a discharging opening are arranged on the working panel. A filter screen is arranged in the filtering opening. The filtering opening is arranged in the water filtering area. The discharging opening is arranged in the discharging area. The squeezing telescopic cylinder is arranged above the water filtering area. A pressing plate is arranged on the moving end of the squeezing telescopic cylinder. The squeezing telescopic cylinder can drive the pressing plate to move downward and press against the squeezing cylinder in the water filtering area. The application reduces the labor intensity, realizes automatic and intelligent operation, makes the water yield of large intestines reach a unified standard, and improves the product quality and work efficiency.

The application provides a compound feed for improving the disease resistance of breeding ducks and a preparation process thereof, and belongs to the technical field of breeding feeds; the preparation process comprises the following steps: preparing modified resistant starch acetate; preparing a bifidobacterium composite microbial agent; preparing a composite nano carrier; preparing an extract composite additive; and preparing a compound feed; after the resistant starch acetate is activated by 1,1-carbonyl diimidazole and then a concanavalin A solution is added for reaction, the modified resistant starch acetate is obtained; after the bifidobacterium is loaded by using the modified resistant starch acetate, the bifidobacterium can be protected from damage by gastric acid and digestive enzymes, and then the number of bifidobacterium reaching the large intestine of the breeding duck is improved, which is beneficial to better inhibiting the reproduction of harmful bacteria in the large intestine of the breeding duck and improving the disease resistance of the breeding duck; in addition, after the resistant starch acetate is modified by using the concanavalin A, the loading rate of the resistant starch acetate to the bifidobacterium is improved.

The present application relates to the technical field of microbial separation, and particularly relates to a separation method and application of intestinal probiotic escherichia; the separation method of intestinal probiotic escherichia is to take bovine large intestine content as raw material, to realize pre-screening of potential colonization strains through mucus anaerobic targeted enrichment, then to obtain resistant colonies through bile salt-short chain fatty acid stress primary screening, to scrape the colonies with metallic luster and fluorescence quenching ring through FITC-labeled mucus fluorescence indication secondary screening, and finally to obtain target strains through multiple PCR screening of negative virulence gene-positive functional gene, to realize directional separation of intestinal probiotic escherichia after purification of nutrient agar; the present application realizes targeted enrichment of intestinal colonization bacteria, environmental tolerance pressure screening and mucus binding visualization identification, solves the problems of strong randomness of traditional probiotic screening and inability to predict colonization potential, and provides a new strategy of efficient and safe probiotic strain screening for development of functional food and microecological preparation.

This invention discloses a method for removing odor from pig intestines, relating to a second aspect of the food processing technology field. The method comprises the following steps: enzyme treatment: papain is added at 0.9%-1.5% of the pig intestine mass, and the treatment is carried out at 45℃-50℃ for 30-60 minutes, followed by thorough rinsing with water; alkali treatment: sodium hydroxide solution is applied at a concentration of 0.8g / L-1.6g / L, and the treatment is carried out at room temperature for 20-40 minutes, followed by thorough rinsing with water; alcohol treatment: ethanol solution is applied at a concentration of 25%-45%, and the treatment is carried out at room temperature for 35-55 minutes, followed by thorough rinsing with water. This invention proposes a three-step synergistic treatment process of enzyme-alkali-alcohol, achieving an odor removal rate of over 80% under mild conditions. This process does not rely on external flavor masking and leaves no undesirable residues.

The present application relates to livestock slaughtering equipment technical field, specifically disclose a kind of casing device, including spray head and composite pipe, composite pipe is supplied with gas and water to spray head, and spray head includes independent and not through each other's air jet layer, forward water jet layer and reverse water jet layer;Wherein, air jet layer is used to transport compressed air in large intestine, forward water jet layer is used to disperse the plug in large intestine, and reverse water jet layer is used to drive large intestine to enter composite pipe.The present application provides the power of enteroclysis through reverse water jet layer, removes the hindrance inside large intestine through forward water jet layer, and the large intestine that has not entered through air jet layer is inflated to straighten the twisted large intestine quickly, directly cancels the operation action of artificial adjustment large intestine.Therefore, the present application greatly reduces the difficulty of manual operation.

The invention provides large intestine targeted release type probiotic soft sweets and a preparation method thereof. The soft sweets comprise functional microspheres and matrix slurry, the functional microsphere comprises a probiotic core layer, a chemotactic signal layer and a targeting layer from inside to outside, the matrix slurry comprises a gelling agent, a sweetening agent, an acidulant, fruit essence and water. The probiotic core layer comprises probiotics and extracellular polysaccharide secreted by the probiotics; the chemotactic signal layer comprises a specific chemotactic agent; the targeting layer comprises an antibacterial peptide which is generated by inducing the probiotics. The functional microspheres provided by the invention can realize targeted release of probiotics in the soft sweets in large intestines, and the matrix slurry enables the soft sweets to have good chewing feeling and to be quickly disintegrated in the stomach to release the microspheres without influencing the functions of the microspheres, and can effectively protect the structures and thallus activity of the microspheres; and the retention rate of viable bacteria in the shelf life is also kept at a relatively high level.

Various of the disclosed embodiments provide systems and methods for determining precise surgical instrument kinematics data, such as the pose of a colonoscope when examining a large intestine. The pose may then be used when constructing of a model of the patient interior from which reference geometries, such as a centerline, and navigational feedback, such as lacunae in the operator's review, may be produced. Some embodiments may also determine a data frame's suitability for downstream processing based upon the intraoperative field of view (e.g., downstream localization and mapping operations), such as whether the frame is undesirably blurred or depicts an obstruction. The operating surgeon, or reviewers of the surgical procedure, may then be presented, e.g., with metrics or graphical feedback related to one or more of: surgical instrument movement relative to the centerline, comprehensiveness of the operator's examination, and the amount of undesirable frames encountered during the examination.

The invention relates to the technical field of in-vitro simulation, and discloses an in-vitro gastrointestinal tract simulation method and system. The method comprises the following steps: acquiring real-time stomach parameters of a stomach simulation area, real-time small intestine parameters of a small intestine simulation area and real-time large intestine parameters of a large intestine simulation area in an in-vitro gastrointestinal tract simulation device; performing quantitative calculation on the acquired real-time parameters to generate a quantitative stomach data set of the stomach simulation area, a quantitative small intestine data set of the small intestine simulation area and a quantitative large intestine data set of the large intestine simulation area; executing simulation state evaluation operation according to the quantitative data set, and outputting a real-time digestion state index of the stomach simulation area, a real-time absorption state index of the small intestine simulation area and a real-time fermentation state index of the large intestine simulation area; and comparing the real-time state index with a predefined threshold interval, and starting a corresponding simulation condition correction operation according to a comparison result.

The present application relates to a kind of based on selective permeable membrane and 3D printing porous carrier large intestine targeted bacteria-loaded pellets, belong to oral large intestine targeted drug delivery technical field, and large intestine targeted bacteria-loaded pellets are obtained by mixed bacteria body being wrapped by semi-permeable shell membrane as shell, the semi-permeable shell membrane is obtained by selective permeable membrane covering 3D printing porous carrier, and the 3D printing porous carrier is used as support skeleton.By mixed bacteria body being wrapped by semi-permeable shell membrane as shell, the semi-permeable shell membrane is obtained by selective permeable membrane covering 3D printing porous carrier, selective permeable membrane is evenly coated on the outer surface and pore inner wall of 3D printing porous carrier, and together form the shell with mechanical strength and large intestine targeted permeability, so that large intestine targeted bacteria-loaded pellets, release rate 3-4% in simulated gastric acid 2 hours, can effectively protect the safety of internal embedded flora through stomach, after entering intestine, release rate 94-96% in 4 hours in large intestine simulation liquid, and cumulative total release rate is as high as 97-99%.

The invention provides a traditional Chinese medicine composition for treating infantile dryness-heat internal stagnation type constipation. The traditional Chinese medicine composition is prepared from radix rehmanniae recen, radix ophiopogonis, radix scrophulariae, immature bitter orange stir-fried with bran, fried fructus cannabis, fried semen raphani, cortex magnoliae officinalis, semen trichosanthis, folium eriobotryae, dark malt, fried endothelium corneum gigeriae galli and honey-fried licorice root. The radix rehmanniae recen in the traditional Chinese medicine composition can strengthen water and nourish yin; scrophularia ningpoensis clears heat, nourishes yin, promotes salivation and activates kidney water to nourish intestinal dryness The radix ophiopogonis can nourish yin and moisten lung, tonify stomach and promote secretion of saliva or body fluid, the lung and large intestine are combined to form a monarch drug, the effects of nourishing yin and clearing heat and nourishing yin of lung, stomach and kidney can be achieved, intestine dryness can be moistened, and excrement can be relieved; the immature bitter orange and the mangnolia officinalis of the Xiaochenqi decoction are taken to lightly lower heat accumulation and are used as ministerial drugs together, and the combined use of the two drugs can enhance the efficacy of regulating qi; meanwhile, folium eriobotryae and snakegourd seeds which have the effects of clearing heat and moistening the lung are used as assistants, so that lung fluid is generated to nourish fluid of large intestines, and qi movement of the intestines and the viscera is smooth; the fructus cannabis used as an assistant and guide for relaxing bowel; as constipation children have symptoms such as inappetence and noxious breath, semen raphani, malt and endothelium corneum gigeriae galli are added to invigorate the spleen and promote digestion.

The invention relates to the technical field of feed additives, and discloses a plant small peptide chelate for an animal feed additive and a preparation method, the chelate is a microcapsule with a multi-layer core-shell structure, the particle size range of the microcapsule is 50-200 [mu] m, and the microcapsule sequentially comprises an active inner core, an active outer core and a plant small peptide chelate from inside to outside, the plant-derived small peptide-microelement chelate composition comprises a plant-derived small peptide-microelement chelate loaded on a dendritic polymer carrier, the intestinal tract positioning release layer wraps the active core and is composed of cross-linked polysaccharide hydrogel, and the cross-linked polysaccharide hydrogel is formed by cross-linking of a cleavable substrate peptide; the anti-oxidation protection layer wraps the intestinal tract positioning release layer; the coat wraps the anti-oxidation protection layer; according to the invention, high temperature and oxidative stress in feed processing and storage are effectively resisted, programmed delivery of stomach protection, precise enzyme trigger release in small intestines and microbe response in large intestines is realized, and the availability of active ingredients is improved.

A method for indicating a part of colonoscopic examination according to the present invention comprises the steps in which: a model loading / condition setting unit loads a colonoscopy image analysis model and sets analysis conditions of the analysis model; a control unit initializes an analysis screen and displays a picture of a normal large intestine; an image preprocessing unit preprocesses a colonoscopy image received via an image reception unit so that subsequent image analysis may be smoothly performed; an image analysis unit analyzes the preprocessed colonoscopy image by using an AI-based image analysis model; the image analysis unit detects and indicates at least one of an examination part, a diverticulum part, or a lesion part from the colonoscopy image on the basis of the analyzed result; and the control unit provides the result analyzed by the image analysis unit.

The application discloses a non-grain raw material processing method and application of a product thereof in pig feed, and belongs to the technical field of feed processing. The processing method takes leaves of broussonetia papyrifera, citrus peel residues and perilla frutescens meal as raw materials, carries out mixing and crushing, adds water to prepare a slurry, adds calcium dihydrogen phosphate and citrate to control pH, carries out in-situ mineralization to make amorphous calcium phosphate and active components co-precipitate and assemble, and then carries out low-temperature drying to obtain composite particles; the product can be applied to full non-grain pig feed as a core functional component, and is suitable for different formulae of piglets, growing pigs and pregnant sows at different stages. The application discloses a trinity composite structure constructed by taking plant cell walls as a natural template, and solves the problems of easy inactivation and low bioavailability of active components of non-grain raw materials, realizes precise delivery of stomach protection-small intestine release-large intestine regulation, significantly improves pig growth performance, immunization level and reproduction efficiency, and provides an efficient technical scheme for industrialization of full non-grain feed.

The utility model relates to enteroscope training model technical field, specifically for a kind of simulation enteroscope training simulation structure, including hollow outer frame, lower digestive tract model is provided with in outer frame by fixed structure;Lower digestive tract model includes successively connected large intestine model and small intestine model, the end of large intestine model is connected with outer frame by simulation anus;The lower digestive tract model of the utility model is made based on real human CT scanning data reconstruction model, and cooperate with the fixed structure of real human pelvic bone and ligament tissue composition, can highly simulate human lower digestive tract structure and enteroscope operating feeling;By being connected with external power supply, the utility model can realize the conductive function when endoscopic operating instrument, complete operation such as electrocision;The utility model can also set up training module inside lower digestive tract model, to simulate different diseases, greatly expand training range, can be applicable to the demand of different levels of physicians for different kinds of enteroscope training simulation.

The provided is a system that provides information with high accuracy by performing voxel-based both cross-sectional and volumetric three-dimensional imaging in cancer tissues, especially in determining the necessary surgical margins of the breast tumor removed from the patient with breast cancer surgery and the presence of the tumor in the sentinel lymph node, which is the first lymph node from which the tumor drained. The provided will not be applied directly to humans and the human body, but to the tumor and / or tumorous tissue removed from the patient's cancerous organ (especially the breast). By changing the software parameters and the applied X-ray range used in breast tumors, a deep technology-based system developed can also be used in human lung, liver, pancreas, thyroid, brain, skin, small intestine, large intestine, stomach, gall bladder, esophagus, bladder, kidney, ovary, uterus, cervix, testis and prostate tumors and tumorous tissue fragments.

The present invention relates to a laparoscopic clasp (1) that during laparoscopic bowel surgery, grasps the inner part of the small or large intestine abdomen with the curved handles (5 or 6) at the end, allowing the intestines to be held securely, pulling the intestines out of the surgical field and performing surgical suturing, resection and vascular ligation by compressing and / or hanging the intestines in the gap between the handles of the right curved handle (6) by hanging with a hooked needle (7.1) at the end of the surgical suture (7), which is passed through the circular gap (2.1 or 3.1) on the flap (2 or 3) to the anterior abdominal wall, which forms the anterior part of the abdominal cavity and spreads to the anterolateral region of the abdominal wall. Laparoscopic bowel surgery is a technique used in the surgical treatment of abdominal organs by making several small holes, usually 0.5 to 2 cm in width, instead of large incisions, and pipes called trocars are inserted into the patient through the holes and carbon dioxide gas is given to the patient's abdomen through these pipes and the patient's abdomen is inflated. Our invention, together with the spring mechanism (4) between the flaps (2 and 3), provides the capture of the segment of the intestine with the curved handles (5 and 6), and functions after it is closed and opened and fixed by hanging on the anterior abdominal wall (with the help of laparoscopic endograsper and endoclinch) lifted by the pressure generated during abdominal distension.

The utility model belongs to physiotherapy device technical field especially relates to a magnetic elbow guard for stimulating hand yangming large intestine meridian acupoints. The utility model discloses an elbow guard body, the elbow guard body is formed around the cylinder through the elastic cloth layer, magnetic particle is arranged on the elbow guard body, the magnetic particle sets up several, and at least is located hand yangming large intestine meridian acupoint's hand five li acupoint, elbow acupoint, Quchi acupoint, hand three li acupoint, lower disapproving acupoint, Wenluo acupoint place. The utility model discloses a plurality of magnetic particles on the elbow guard, for actively or passively stimulating relevant acupoints, passively stimulating relevant acupoints realizes the effect of continuous pressing, also can press the magnetic particle with another hand to realize active stimulation relevant acupoints, to obtain higher intensity stimulation. The utility model magnetic particle can concentrate the magnetism more in the acupoint vicinity, plays the effect of better magnetotherapy.

The invention discloses a medicinal moxa composition for preventing and treating hemorrhoids and abnormal leucorrhea. The medicinal moxa composition comprises radix angelicae, radix aucklandiae, betel nuts, radix puerariae and moxa. Based on the theory of'lung dominating large intestine and spleen dominating transportation and transformation ', the medicinal folium artemisiae argyi composition disclosed by the invention starts from the large intestine channel of hand-yangming, has the effects of clearing away heat and toxic materials, promoting the circulation of qi and removing stagnation, raising yang and stopping diarrhea and the like, and simultaneously improves abnormal symptoms of haemorrhoids and leucorrhea. The five medicines are compatible to form a balanced system for clearing away heat and toxic materials, promoting the circulation of qi and removing stagnation, and promoting the circulation of yang and stopping diarrhea; the radix angelicae dahuricae is used for clearing away heat and toxic materials; the radix aucklandiae is used for promoting the circulation of qi and removing stagnation; the radix puerariae is used for promoting the circulation of yang and stopping diarrhea. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for remarkably improving bleeding and pain symptoms of patients suffering from haemorrhoids and regulating vaginal micro-ecological balance of patients suffering from abnormal leucorrhea at the same time.

In the endoscopic examination support apparatus, the image acquisition means acquires an endoscopic image taken by an endoscope. The first lesion detection means detects a lesion candidate from the endoscopic image, using a machine learning model that learned a relationship between the lesion candidate and a normal state of a large intestine. The second lesion detection means detects a lesion candidate from the endoscopic image, using a machine learning model that learned a relationship between the lesion candidate and a predetermined state of the large intestine. The output means outputs at least one of a detection result of the first lesion detection means and a detection result of the second lesion detection means.