132 results about "Large intestine" patented technology

A lumen organ model and an endoscope training system are provided. A luminal organ model (3) is provided with: a model body (11) comprising a hollow lumen body having a lumen surface that simulates at least the lumen of a luminal organ such as the stomach, the large intestine, the bladder, the paranasal sinus, or the uterus; a light source device (13) that emits light in a light-emitting region disposed at at least one predetermined observation site corresponding to a training purpose on the lumen surface of a model body (11) comprising a lumen; and a processor (27) that selectively switches light-emitting regions that emit light by controlling the light source device (13).

The invention provides a preparation method, application and the like of large intestine expression recombinant A-type botulinum toxin (BONT / A). The recombinant BONT / A nucleic acid expression cassette comprises a tag, a restriction enzyme cutting site and a BONT / A nucleic acid sequence, and an exogenous protease recognition site is not introduced between a BONT / A light chain and a BONT / A heavy chain. The invention also provides a recombinant vector containing the nucleic acid expression cassette, a recombinant bacterium, a coded and expressed protein and the like, the prepared recombinant BONT / A does not introduce exogenous amino acid or only introduces two amino acids at one position, and the consistency of the recombinant BONT / A with the natural A-type botulinum toxin is ensured to the greatest extent. Through novel molecular design and preparation process, the recombinant reBONT / A with higher toxicity and low immunogenicity is efficiently obtained, and wide industrial application is facilitated.

The invention discloses a digestible quality analysis system for chicken feed, relates to the technical field of chicken feed analysis, and aims to solve the problem of poor simulation effect of digestion of the chicken feed. According to the method, low-temperature and high-temperature staged drying treatment is adopted, the characteristics of components such as moisture and fat in the residues are fully considered, the secretion rules of different alimentary canal parts of animals are simulated, sufficient and reasonable contact of digestive juice and feed is ensured, the simulation process is closer to the real physiological condition, and the situation that the digestion analysis result is affected by liquid amount errors is avoided; animal digestive tracts are scientifically segmented into stomach, small intestine and large intestine stages, corresponding external buffer solution and internal digestive juice are injected respectively, and a real digestion scene is comprehensively simulated from a physical structure to a chemical environment.

The present invention relates to vitamins for use in improving gut health in animals and humans. In particular, it was found that, upon delivery to the large intestine, vitamin B2, vitamin C, and vitamin D can be used for increasing the abundance of the beneficial bacteria Bifidobacterium animalis ssp. lactis in the intestinal tract.

A bioflexible elastomer intestinal anastomosis stent based on a PTMC-b-PEG-b-PTMC copolymer, and a preparation method. Biocompatible degradable polymer medical materials, i.e., PTMC and PEG, are selected, an electrostatic spinning method is used for preparation, the size of an anastomosis tube can be adjusted according to the size of a human lumen, and the anastomosis tube is designed to not only be suitable for an anastomat of the small intestines and large intestines, but also suitable for an anastomotic and pre-supported lumen anastomat of an esophagus, artery, vein, etc. The anastomosis tube prepared has a thin wall and excellent elasticity, and in order to facilitate suturing by a doctor during a clinical surgical operation, the anastomosis tube is innovatively and seamlessly sleeved outside a plant cellulose tube having high hardness.

The utility model provides a disposable haemorrhoids treatment suppository, which comprises a treatment suppository body, the treatment suppository body comprises a suppository head, corrugated bulges, a cap, a capacity bin, a suppository tail, external threads and helical teeth, the surface of the suppository head is provided with a plurality of corrugated bulges, and a space is arranged between every two adjacent corrugated bulges. A bolt tail is integrally formed at the top of the bolt head, an opening is formed in the end of the bolt tail, a cover cap is arranged on the surface of the bolt tail in a sleeving mode, and oblique teeth are integrally formed on the side edge of the bolt tail. According to the haemorrhoids treatment suppository, the sealing effect on the suppository tail part is achieved through the additionally arranged cap structure, the cap can only be tightened but cannot be unscrewed, it is ensured that the problem of loosening after sealing is completed cannot occur, and the probability of liquid leakage is reduced. A plurality of corrugated bulge structures are additionally arranged on the suppository head part, and the contact surface with the large intestine can be effectively increased through the corrugated bulges, so that the overall treatment effect is better.

An ingestible in-vivo gastrointestinal device constituted of: a power source; a processor and a memory; and a sensor, the processor, at least partially responsive to the sensor, to determine a location of the in-vivo gastrointestinal device as being in one of an esophagus, a stomach, a small intestine and a large intestine of a subject.

The present invention relates to an artificial digestive tract tissue for training in endoscopic submucosal dissection (ESD) and a method for manufacturing the same. Specifically, the invention relates to an artificial digestive tract tissue configured to mimic the mucosal layer, submucosal layer, and muscle layer constituting the human digestive tract tissue in a multilayer structure, such that swelling occurs upon liquid injection and a color change occurs due to changes in salt concentration, and to a casting and curing-based hydrogel molding process for manufacturing the same. According to the present invention, the problems associated with existing animal tissue-based ESD training simulators can be resolved, repeated use is possible, and training tailored to the structural characteristics of specific organs (stomach, large intestine, small intestine, etc.) is possible.

The present application relates to an oral polypeptide composition system stably absorbed in the gastrointestinal tract, and specifically discloses an oral polypeptide composition. The composition comprises a polypeptide molecule (A), a surfactant (B), an amino acid monomolecular or a bimolecular combination (C). The molecular weight of a peptide drug used as a drug in the oral polypeptide composition is within a range of 0.1 kDa to 20 kDa. The action part of the composition system is small intestine or large intestine; and the polypeptide composition has obviously improved and increased stability and absorbability in the gastrointestinal tract.

1. The name of this design product: Food packaging bag (clear water large intestine). 2. Purpose of this design product: used as food packaging bag. 3. The key design point of this design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the key points of the design: main view. 5. This design is a thin product, and the left view, right view, top view, bottom view, and stereoscopic view are omitted. 6. Other situations that require explanation Other explanations: The gray area marked "B" in the rear view is made of transparent material.

According to the application plaster formula for treating abdominal distension and constipation and the application method thereof, the effective components of the medicine are absorbed by stimulating acupuncture points, so that the effect of preventing and treating abdominal distension and constipation is achieved. The traditional Chinese medicines are ground into powder, the powder is blended into paste with normal saline, the paste is applied to an adhesive plaster, and the paste is applied to the acupoints of the abdomen (Shenque and Tianshu), the back (large intestine shu and small intestine shu) and the legs (Zusanli and upper giant deficiency), the Tianshu is the acupoint of the large intestine in the abdomen, the large intestine shu and the small intestine shu are the large intestine, and the back shu-acupoint of the small intestine in the back. Zusanli and upper giant deficiency are stomach meridian and large intestine meridian at the lower he acupoints of the legs. The compatibility of the acupuncture points embodies the compatibility use of the Yu-Mu matched acupuncture point and the Xiahe acupuncture point. The effect is better than that of purely applying to the Shenque acupoint. The traditional Chinese medicine composition conforms to the traditional Chinese medicine composition principle and the acupoint compatibility principle, the effect is better than that of single medicine and single acupoint application, and application transdermal absorption is easier to accept by people compared with oral medicine.

The utility model discloses a limit structure of a intestine scraping machine, which relates to the technical field of intestine scraping machine equipment and comprises a base, an extrusion device is arranged at the upper end of the base, limit frames are symmetrically and fixedly mounted at the upper end of the base, limit mechanisms are arranged at the lower ends of the limit frames, and the same linkage mechanism is arranged on the outer sides of the limit mechanisms. By adopting the structure, the two-way screw rod in the limiting frame rotates in the mounting groove, so that the two movable rods in threaded connection with the outer side of the two-way screw rod can slide close to each other or away from each other, and safe limiting adjustment is achieved according to the guide mark frame and the graduated scale in combination with the processing amount of a large intestine; the lower half part of the moving rod is rotationally provided with the rod sleeve through the limiting rod, and the large intestines processed by the extrusion device can be conveniently limited by utilizing the rod sleeve after proper adjustment, so that the conditions of excessive deviation, displacement and the like in the processing process of the large intestines are avoided.

Aspects of the present disclosure relate to compositions and methods for treating one or more inflammatory bowel diseases ("IBD"), such as ulcerative colitis ("UC") and / or Crohn's disease. Some embodiments relate to a pharmaceutical dosage form comprising a core comprising an inhibitor of a protease (e.g., a bacterial protease) and a controlled release coating applied to an outer surface of the core. In some cases, the protease inhibitor is a gligliptin or a pharmaceutically acceptable salt thereof. In some cases, the controlled release coating is configured to release the protease inhibitor in the large intestine (e.g., colon) and / or small intestine of a subject administered the pharmaceutical dosage form. Some embodiments relate to methods of treating one or more IBDs comprising delivering a therapeutically effective amount of an inhibitor of a protease (e.g., bacterial protease) to the large intestine (e.g., colon) and / or the small intestine of a subject.

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory bowel diseases, comprising Lactobacillus murinus as an active ingredient. More specifically, it has been identified that drinking three times a week significantly reduces the length of the large intestine in comparison to other drinking patterns, and it has been identified that by administering Lactobacillus murinus, intestinal inflammation is improved such as with respect to large intestine length restoration and an increase in goblet cell count, and thus the present invention can be variously utilized as a therapeutic agent for inflammatory bowel disease, a health functional food composition and the like.

[Problem] To provide a method or program for obtaining a virtual large intestine cleansing image that can remove residual matter from large intestine imaging data captured without the use of laxatives. [Solution] The method includes: an image input step, in which a captured image representing a part of a patient's large intestine is input; and a virtual large intestine cleansing step, in which a virtual large intestine cleansing image representing a part of the patient's large intestine with residual matter removed from the captured image is obtained. The invention also provides a program for causing a computer to execute the above method for obtaining virtual large intestine cleansing images.

Disclosed are a system and method for analyzing a stool image, which derive the state of the large intestine of a user by analyzing a stool image by using a pre-trained deep learning model. The system for analyzing a stool image may include an input unit configured to receive stool images of a user, a data set generation unit configured to generate a data set by grouping the stool images in chronological order, an analysis unit configured to derive information on a stool state of the user or information on a state of the large intestine of the user by analyzing the data set, and an output unit configured to output the information on the stool state or the information on the state of the large intestine. The endoscopic activity of ulcerative colitis can be predicted from a camera image of stool even without performing a colonoscopy.

1. Name of the designed product: packing box (white water intestine). 2. Use of the designed product: for packing sausage. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: perspective view.

The utility model relates to a cloth-saving wave-edge hair band, which comprises a cylindrical cloth strip and rubber bands, the outer side of the cylindrical cloth strip is provided with a concave-convex wave structure, the rubber bands are arranged in the cylindrical cloth strip, the cylindrical cloth strip is connected end to end to form a ring shape, the rubber bands are connected end to end in the cylindrical cloth strip, and the rubber bands are arranged in the cylindrical cloth strip. The edge of the cloth-saving rippled-edge hair band is wavy, the rippled-edge effect generated after the cloth of a traditional large-intestine hair band is shrunk and folded can be simulated, compared with the traditional large-intestine hair band made of cloth with the same length, the waves of the cloth-saving rippled-edge hair band look more and more fluffy, the hair band with more and larger waves can be made of less cloth, and the cloth-saving rippled-edge hair band is more attractive in appearance. Therefore, the cloth is saved, the production cost is reduced, even if the rubber band in the cloth-saving rippled-edge hair band is enlarged, the rippled edge still exists all the time, and the problem that the rippled edge disappears and loses aesthetic feeling when the rubber band in a traditional large intestine hair band is enlarged and wound on hair is solved.

The invention provides a general induction method for original digestive tract partition. The method comprises the following steps: high-quality human pluripotent stem cell verification, pluripotent stem cell sensitivity test, cell inoculation and start convergence degree verification, endoderm-mesoderm co-induction, original digestive tract induction and original digestive tract partition. Compared with a traditional method, on the premise of not depending on serum, original digestive tract partition derivatives (in a 3D sphere form) of different organs such as lungs, stomachs, livers, pancreas, small intestines and large intestines can be efficiently generated, and subsequent batch preparation of final products is facilitated. The method is helpful for promoting large-scale industrial transformation and application of respiratory digestive tract organs.

The present invention relates to the field of biotechnology. Specifically, it relates to a co-fermentation method of Clostridium butyricum and Lactobacillus amylovorans. The co-fermentation method uses a compound preparation, and the compound preparation contains a Lactobacillus amylovorans and Clostridium butyricum. The Lactobacillus amylovorans is Lactobacillus amylovorus, and its strain number is RZ-D4L1, which is preserved in the China Center for Type Culture Collection, and the preservation number is: CCTCC NO: M 2024761; the Clostridium butyricum HZNDC-1 is isolated from the large intestine of cattle, and is preserved in the China Center for Type Culture Collection, and the preservation number is: CCTCC NO: M 2021874. The co-fermentation of the present invention can improve the fermentation stability of Clostridium butyricum, and at the same time, there is also a significant increase in the viable cell count and sporulation rate of Clostridium butyricum, providing a new fermentation method for the high-density fermentation of Clostridium butyricum, which can increase the probiotic performance of the fermentation supernatant, improve the utilization value of the waste liquid of Clostridium butyricum, and has great popularization and application value.

The application discloses an LNG ship liquid cargo tank based on a large intestine structure, wherein a spherical main screen wall comprises a main screen wall body and a heat insulation material layer. A wall surface of the main screen wall body is in a large intestine wall structure, and an outer surface of the main screen wall body is coated with the heat insulation material layer. A hemispherical secondary screen wall covers an upper hemisphere of the spherical main screen wall. A pipe tower vertically penetrates from a top of the hemispherical secondary screen wall to an inside of the spherical main screen wall. The spherical main screen wall is embedded in a groove of a circular opening of a ship body. A drip receiving tray is connected with a bottom of the groove. An equator edge of the hemispherical secondary screen wall is connected with the ship body at the circular opening of the groove through a skirt support structure. A hatch cover covers a part of the hemispherical secondary screen wall exposed to the ship body. The application improves a deformation capacity of the liquid cargo tank, i.e. an expansion and contraction deformation capacity caused by temperature change, and effectively reduces thermal stress. The inner screen wall structure in the bionic large intestine wall has the effects of reducing a liquid free surface area, slowing down liquid sloshing and improving ship body stability, and enhances safety of the LNG ship liquid cargo tank.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating condyloma acuminatum and application. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 15 to 20 parts of spica prunellae, 10 to 15 parts of cortex phellodendri, 10 to 15 parts of herba taxilli, 10 to 20 parts of fructus mume, 10 to 15 parts of radix sophorae flavescentis, 30 to 35 parts of gallnut and 30 to 35 parts of endothelium corneum gigeriae galli. According to the traditional Chinese medicine composition for treating condyloma acuminata, the seven medicines are properly matched, the syndrome differentiation is comprehensive, deficiency and excess are taken into consideration, and channel tropism mostly enters the liver channel of foot syncope yin and the large intestine channel of hand yangming are separated from front yin and rear yin. The acetic acid is used as a solvent, so that the channel guiding effect is better, and the effect taking speed is higher.

The invention relates to the technical field of bioengineering, in particular to a bionic modular in-vitro large intestine fermentation simulation model, an evaluation method and application. The large intestine fermentation simulation model is composed of a fermentation cavity module, a detachable mucus layer module, a detachable pH regulation and control module and a gas production monitoring module. The method comprises the following steps: constructing a modularized in-vitro large intestine fermentation simulation model, adding prebiotics and a basal culture medium, inoculating excrement homogenate, controlling parameters in an anaerobic fermentation process, monitoring the gas yield in the fermentation process, and determining the composition of metabolites and intestinal flora after fermentation is finished. The system adopts an anti-interference material and a dynamic environment control technology, so that the stability of anaerobic conditions is ensured, and the problems of material degradation and ion pollution of a traditional device are avoided. And the experiment flux and efficiency are greatly improved. The device has excellent reuse performance, key parts still keep stable functions after being sterilized for multiple times, the maintenance cost is remarkably reduced, and the consistency and repeatability of experimental data are guaranteed.

The utility model belongs to the technical field of slaughtering equipment, and particularly discloses large intestine pigment removing equipment which comprises a rubbing mechanism, a water channel mechanism, a water outlet mechanism and a water outlet mechanism, the rubbing mechanism is used for rubbing off pigment on the surface of a large intestine and comprises an inner barrel used for containing the large intestine, the periphery of the inner barrel is wrapped with an outer barrel, the outer barrel is communicated with the water channel mechanism, and a water inlet hole is formed in the inner barrel; the water path mechanism comprises a water inlet device and a water outlet device, and the water inlet device and the water outlet device are used for water inlet and water outlet of the outer barrel respectively. Red melanin on the surface of the large intestine is rubbed off by adopting a physical method, and then the large intestine is soaked and washed through the outer barrel, so that the color of the large intestine is close to yellowish white, and the sales demand is met.

The utility model discloses an anti-pollution enteroscope assist device, and relates to the technical field of medical equipment. Comprising a rotating plate and an auxiliary clamping structure, the auxiliary clamping structure is arranged on the rotating plate and comprises a lower half clamping frame, a rotating clamping frame, an extending half frame, a lantern ring and a rubber ring, one side of the outer wall of the lower half clamping frame is fixedly arranged on the rotating plate, one side of the outer wall of the rotating clamping frame is rotationally embedded in the rotating plate, one side of the outer wall of the extending half frame is fixedly arranged on the rotating plate, and the lantern ring is arranged in the extending half frame. The inner wall of the lantern ring is slidably arranged on the extending half frame in a sleeving mode, and one side of the outer wall of the rubber ring is fixedly arranged on the lantern ring. By means of the lower half clamping frame, the rotary clamping frame, the extending half frame, the lantern ring and the rubber ring, the auxiliary part of the enteroscope can be fixed to the bedside, the enteroscope penetrates through the auxiliary part and slowly stretches into the large intestine, the enteroscope is supported and is more stable in the stretching process, medical workers can conveniently free hands to conduct other detection operation, and the labor intensity of the medical workers is relieved. And convenience is provided for medical staff.

Various disclosed embodiments provide systems and methods for determining precise surgical instrument kinematic data, such as the pose of the colonoscope when examining the large intestine. The pose may then be used in building a model inside the patient from which reference geometry, such as a centerline, and navigation feedback, such as an omission in viewing by the operator, may be generated. Some embodiments may also determine the suitability of the data frame to downstream processing (e.g., downstream positioning and mapping operations) based on the intra-operative field of view, such as whether the frame is undesirably obscured or depicts an obstacle. Metrics or graphical feedback may then be presented to the operating surgeon or viewer of the surgical procedure, e.g., relating to one or more of the surgical instrument movement relative to the centerline, the comprehensiveness of the examination by the operator, and the amount of undesired frames encountered during the examination.

The invention relates to the technical field of animal medicines, and particularly discloses a veterinary medicine compound preparation as well as a preparation method and application thereof. The veterinary medicine compound preparation is prepared by boiling, extracting, concentrating and diluting eight Tibetan medicines including aconitum pendulum, fructus chebulae, radix inulae inula, benzoin, pterocephalus hookeri, lagotis lagotis, amomum tsao-ko and rhodiola rosea. The veterinary drug compound preparation provided by the invention has an antibacterial range of 8.67 mm to 23.77 mm on enterotoxic large intestine dried bacteria, salmonella enteritidis and pasteurella multocida, and has an inhibition rate of 60% to 72% on enterotoxigenic escherichia coli diarrhea, salmonella enteritidis diarrhea and pasteurella multocida diarrhea; therefore, the veterinary drug compound preparation provided by the invention has a remarkable inhibition effect on enterotoxic large intestine dry bacteria, salmonella enteritidis and pasteurella multocida.

The present invention relates to the use of a tomato extract for modulating the gut microbiota in a subject to confer a health benefit, and to a composition containing a tomato extract formulated for delivery to the large intestine. The tomato extract can be used to improve resistance to infection in the gut, reduce inflammation in the gut, treat or minimize inflammatory bowel disease, or treat or minimize irritable bowel syndrome. The extract can also be used to treat conditions associated with an imbalance of the gut microbiota such as anxiety, depression, type II diabetes, non-alcoholic fatty liver disease, obesity, or cognitive impairment.

To solve the problem of the present invention, a biological electrode for measuring an action potential of an intestine and predicting a defecation timing based on the potential waveform, an intestinal potential measuring device using the biological electrode, and a defecation prediction method are provided. The biological electrode (2) includes a sheet body (3) having a back surface (31) as an attachment surface (31). The sheet body (3) includes a plurality of electrode patch portions (300, 301) that can be arranged at intervals along an intestinal canal (91) of a large intestine and have electrodes (4) for acquiring an intestinal potential exposed on the back surface (31), a central device mounting portion (310, 301) that is arranged within a range in which the plurality of electrode patch portions (300, 301) are annularly connected and has a plurality of connected terminals (311) that are electrically connected to connection terminals (50) of an electrogastrograph (5) and a mounting portion (312) for temporarily fixing a temporary fixing portion (51) of the electrogastrograph (5) exposed on a surface (30), and a lead wire extension portion (320, 321) in which lead wires (322) that connect the plurality of electrode patch portions (300, 301) and the plurality of connected terminals (311) are fixed, respectively.

The invention relates to a vibrating fecal evacuator. More particularly, the invention relates to a vibrating fecal evacuator that abrades and evacuates the mass in the intestine in a controlled manner and without causing side effects, especially for individuals suffering from constipation due to an excessively hardened fecal mass in the large intestine that blocks normal defecation.