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1'-substituted pyrimidine n-nucleoside analogs for antiviral treatment
Active
US20120263678A1
Improve cell selectivity
Inhibition of replication
Biocide
Sugar derivatives
Pyrimidine
Nucleoside Analogs
Provided are compounds of Formula I:nucleosides,
nucleoside
phosphates and prodrugs thereof, wherein R6 is CN, ethenyl, 2-haloethen-1-yl, or (C2-C8)-alkyn-1-yl. The compounds, compositions, and methods provided are useful for the treatment of
Flaviviridae
virus
infections.
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Owner:
GILEAD SCI INC
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