1403 results about "Delivery efficiency" patented technology

The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule to a cell, and assays for optimizing the delivery efficiency of such lipid-based formulations.

The present invention provides lipid-based formulations for delivering, e.g., introducing, nucleic acid-lipid particles comprising an interference RNA molecule to a cell, and assays for optimizing the delivery efficiency of such lipid-based formulations.

The present invention discloses simple and yet highly efficient configurations of optical coherence domain reflectometry systems. The combined use of a polarizing beam splitter with one or two polarization manipulator(s) that rotate the returned light wave polarization to an orthogonal direction, enables one to achieve high optical power delivery efficiency as well as fixed or predetermined output polarization state of the interfering light waves reaching a detector or detector array, which is especially beneficial for spectral domain optical coherence tomography. In addition, the system can be made insensitive to polarization fading resulting from the birefringence change in the sample and reference arms. Dispersion matching can also be easily achieved between the sample and the reference arm for high resolution longitudinal scanning.

An aerosol transfer device (10) for medical aerosol generators comprises a body (12), fluidically coupled to a nebulizer (14) and to a patient interface (16). An ambient air intake (20) is formed into a lower body (12C). The body is shaped and configured to optimize mixing of ambient air from the ambient air intake and the aerosol generated by the nebulizer, resulting in the formation of an aerosol plume having optimum characteristics for delivery of the aerosol to the patient's pulmonary system, such as the central or deep lung regions. The shape and dimensions of the body are further designed to minimize aerosol deposition, thus improving delivery efficiency.

The present invention discloses simple and yet highly efficient configurations of optical coherence domain reflectometry systems. The combined use of a polarizing beam splitter with one or two polarization manipulator(s) that rotate the returned light wave polarization to an orthogonal direction, enables one to achieve high optical power delivery efficiency as well as fixed or predetermined output polarization state of the interfering light waves reaching a detector or detector array, which is especially beneficial for spectral domain optical coherence tomography. In addition, the system can be made insensitive to polarization fading resulting from the birefringence change in the sample and reference arms. Dispersion matching can also be easily achieved between the sample and the reference arm for high resolution longitudinal scanning.

The invention comprises a multi-field charged particle irradiation method and apparatus. Radiation is delivered through an entry point into the tumor and Bragg peak energy is targeted to a distal or far side of the tumor from an ingress point. Delivering Bragg peak energy to the distal side of the tumor from the ingress point is repeated from multiple rotational directions. Preferably, beam intensity is proportional to radiation dose delivery efficiency. Preferably, the charged particle therapy is timed to patient respiration via control of charged particle beam injection, acceleration, extraction, and / or targeting methods and apparatus. Optionally, multi-axis control of the charged particle beam is used simultaneously with the multi-field irradiation. Combined, the system allows multi-field and multi-axis charged particle irradiation of tumors yielding precise and accurate irradiation dosages to a tumor with distribution of harmful irradiation energy about the tumor.

A biodegradable, mixed polymeric micelle used to deliver a selected nucleic acid into a targeted host cell contains an amphiphilic polyester-polycation copolymer and an amphiphilic polyester-sugar copolymer. The polyester-polycation copolymer forms an electrostatic interaction with polyanionic nucleic acids, and the polyester-sugar copolymer directs the micelle-nucleic acid complex to cells in vivo. Additional copolymers with similar properties may also be included. The composition improves delivery efficiency by providing a particulate gene carrier for which particle size and charge density are easily controlled by multivariate means. Various kinds of ligands and other functional compounds may be also be introduced using the composition. The composition may be used in a method for transforming a targeted host cell with a selected nucleic acid.

The invention discloses an intelligent scheduling system for tail-end instant logistics. The intelligent scheduling system comprises an order receiving module, an order processing module, a deliveryman searching module, an order combination module, a merchant portrait module, a deliveryman portrait module, an order dispatching decision-making module, and a deliveryman examination module. On the basis of position information of a merchant and a user as well as positioning information generated by a deliveryman terminal APP, global optimal matching is carried out on an order and a deliveryman by considering the current position of the deliveryman, the order executed by the deliveryman, portrait image of the merchant and the deliveryman, and the requirement on allocation time by the user comprehensively and then an optimal deliveryman is determined finally to complete a delivery task. On the basis of the intelligent order dispatching way, optimal order distribution is carried out at a global angle to realize optimal utilization of the whole transport capacity; the need of instant logistics and the transport capacity supply can be balanced well; the logistics delivery efficiency can be improved; the logistics delivery cost can be lowered; and the service quality of the tail-end instant logistics can be improved.

The invention relates to an electronic commerce supply chain management system, comprising a purchasing management unit, a marketing management unit, an order-receiving management unit, a warehousing management unit, an authority management unit and a system management unit, wherein the electronic commerce supply chain management system performs unified and coordinated management on the purchasing, marketing, order-receiving, warehousing, settlement, authority-controlling, basic information, and internal and organizational structures of the system of commodities, and completes the corresponding function by each executing unit, so that the purchasing, marketing, warehousing and inventory become very clear; the electronic commerce supply chain management system does not only save a lot of manpower and material resources, but also shortens a large amount of process, and optimizes the picking, allocation and delivery procedures, so that the user saves a lot of staff and express costs; and the electronic commerce supply chain management system further greatly shortens the delivery cycle, and improves the delivery efficiency, so that the user can complete the whole logistics procedure from purchasing to delivering of the commodities more rapidly and frugally.

The invention discloses an information processing method, a server and a logistics terminal. The processing method include: receiving an inquire request sent by the logistics terminal; determining target order information corresponding to an authentication logo and containing a delivery address which uses a current position of the logistics terminal as a center and is in a delivery distance threshold value range in at least one order which is prestored; feeding decided target order information back to the logistics terminal; and pushing on-line prompt information to corresponding order user terminals according to order user accounts in target orders after arrival notice instructions sent by the logistics terminal are received. After logistics staff arrive at a delivery plate, a plurality of order users in specific delivery areas can be informed simultaneously according to a mode that the server pushes information to order user terminals, every order user does not need to be informed to take delivery of goods by phone, and purposes of improvement of goods delivery efficiency and reduction of delivery cost are achieved.

The disclosed invention relates to methods of modifying peptide compositions to increase stability and delivery efficiency. Specifically, the disclosed invention relates to methods to increase the stability and delivery efficiency of protein kinase C (PKC) modulatory peptide compositions. A “therapeutic peptide composition” comprises a “carrier peptide” and a “cargo peptide.” A “carrier peptide” is a peptide or amino acid sequence within a peptide that facilitates the cellular uptake of the therapeutic peptide composition. The “cargo peptide” is a PKC modulatory peptide. Peptide modifications to either the carrier peptide, the cargo peptide, or both, which are described herein increase the stability and delivery efficiency of therapeutic peptide compositions by reducing disulfide bond exchange, physical stability, reducing proteolytic degradation, and increasing efficiency of cellular uptake.

The invention provides a vehicle-express delivery cabinet-unmanned aerial vehicle-based express delivery method. According to the method, express items to be delivered are orderly placed in an express delivery cabinet on an intelligent transport vehicle; after the intelligent transport vehicle reaches a destination based on a planned route, recipients are informed to pick up the express items from the vehicle-mounted express delivery cabinet; if the recipients cannot come to pick up the express items and demand that the express items should be delivered via an unmanned aerial vehicle, a vehicle-mounted controller controls an inner cabinet door of the express delivery cabinet to open, a minisize piler is controlled to take the express items from the express delivery cabinet to a cargo pickup opening of the unmanned aerial vehicle, and at last the unmanned aerial vehicle picks up the express items and completes final delivery. The delivery and transport method designed in the invention is based on combination of the intelligent automobile and the express delivery cabinet and / or the unmanned aerial vehicle; consumption of resources such as labor force, vehicles, fuel and the like can be reduced; express delivery efficiency in remote areas can be improved.

An improved illuminator for generating broadband light, and for delivering the light to a sample with an improved delivery efficiency, for higher optical density and / or reduced thermal transfer, than achieved with conventional halogen bulb sources. The illuminator enables spectroscopic analysis in thermally-sensitive or spatially-constrained environments. A phosphor-coated broadband white LED and integrated collimating optics produces a continuous, collimated broadband light beam from 400 nm to 700 nm, which is then transmitted through space to a sample region, such as a living tissue in vivo. A method and system for measuring oxigeneration of mucosal or subsurface tissue is also described.

An improved illuminator for generating broadband light, and for delivering the light to a sample with an improved delivery efficiency, for higher optical density and / or reduced thermal transfer, than achieved with conventional halogen bulb sources. The illuminator enables spectroscopic analysis in thermally-sensitive or spatially-constrained environments. A phosphor-coated broadband white LED and integrated collimating optics produces a continuous, collimated broadband light beam from 400 nm to 700 nm, which is then transmitted through space to a sample region, such as a living tissue in vivo. This results in a high net efficient delivery of light to the tissue sample. An efficient conversion of power to light, and the high delivery efficiency, keeps both the illuminator and sample cool during operation, allowing the illuminator to be integrated into the tip of a medical probe or into monitoring systems.

The invention provides a self-service type article transmitting and receiving system which comprises a server, a mobile terminal and self-service deliver boxes. The server comprises a box body maintaining unit and a box opening processing unit, the mobile terminal comprises an article sending request unit and a feedback receiving unit, each self-service deliver box comprises only one identification, a plurality of box bodies of different types, an input device and a box body control unit, and the box bodies are used for storing articles. The invention further provides a self-service type article transmitting and receiving method and the mobile terminal. The mobile terminal launches the request to the server, the server controls the self-service deliver boxes to deliver articles, self-service delivery can be carried out through the popularized mobile terminal and the self-service deliver boxes, delivery procedures are simplified, and delivery efficiency is improved.

The invention discloses an intelligent logistics delivery method, an apparatus, and a system. The method includes: when it is detected that a delivery mobile client enters a network coverage of intelligent lockers, description information of a delivered item is obtained from the delivery mobile client and sent to a server in order to verify whether the delivered item is matched with the intelligent locker; a door of the locker is opened according to a door-opening instruction in verification result information returned by the server; when it is detected that the storage of the delivered item is accomplished, pick-up notification information is generated, and the pick-up notification information is sent to a reception mobile client; and when it is detected that the reception mobile client enters the network coverage of the intelligent lockers, pick-up verification information is obtained from the reception mobile client, the match between the obtained pick-up verification information and the pick-up verification information in the pick-up notification information is performed, and the door of the locker is opened if the matching is successful. According to the method, the apparatus, and the system, compared with the prior art, the delivery process can be simplified, and the delivery efficiency is improved.

The invention discloses an energy-saving heat supply system with a function of reducing the temperature of heat supply return water, and belongs to the field of improvement of energy utilization efficiency. Heat exchange can be repeatedly carried out on heat sources by multistage heat exchangers, multistage absorption heat exchange units, multistage compression heat pumps and an ice making type refrigerator, accordingly, the heat supply areas can be enlarged, and the energy utilization efficiency can be improved. The energy-saving heat supply system has the advantages that the temperature of the return water of heat supply primary pipe networks can be reduced and reach 0 DEG C, the return water contains 10% of ice particles, accordingly, route heat loss of the return water of the heat supply primary pipe networks can be reduced, the temperature difference of the return water of the heat supply primary pipe networks can be increased and reaches 118 DEG C from the original 60 DEG C, the flow rate of circulating water of the heat supply primary pipe networks can be lowered, energy consumption of circulating pumps can be reduced, heat supply flow rates of a user side can be greatly increased, the delivery efficiency of the pipe networks can be improved, the heat supply scale can be expanded, waste heat of a cooling tower can be recycled, and the like.

The invention discloses a logistic system delivery scheduling method and system. Through a system order distribution mode, rapid matching of an optimal deliveryman can be realized, an order merging rate is improved, artificial order distribution cost is substantially saved, deliveryman experience requirements are reduced, order grabbing burden and risks can be avoided, maximized order merging is realized, delivery efficiency is improved, delivery experience is enhanced, delivery cost is reduced, and integral system efficiency is improved. The system comprises a service end and a delivery end, and the two ends realize communication through the mobile Internet.

The invention discloses a postal service robot which is applied to a logistics company. The postal service robot is characterized by comprising apery limbs, a human-machine intercom system, a navigation system and a 3D (three-dimensional) vision system, which are respectively and independently connected with a data processing module and used for transmitting the data in a bi-directional manner. The postal service robot has the advantages that the automation for delivering mails can be realized, the manual delivery is changed to the automatic delivery of the robot, the unfavorable influence of multiple factors on the delivery quality can be avoided, the manpower of the logistics company is reduced, and the delivery efficiency is greatly improved.

The invention discloses a method for delivering goods by using a password locker. The method comprises the following steps that: a courier first inputs a user ID of an owner and mobile phone numbers of the own and the courier, and selects a locker number according to feedback use state information of each locker; a central control unit automatically opens a corresponding locker door; when the goods are placed in the locker and the locker door is closed well, the courier prints a goods deposit information voucher, and sends locker number information of the deposited goods and a goods fetching password to the owner through a mobile phone short message platform; when receiving the short message and preparing to fetch the goods, the owner inputs the user ID and the goods fetching password, and pays according to feedback payment information; the central control unit automatically opens the locker door after receiving the payment information; and the owner prints a goods fetching information voucher after taking the goods out and closing the locker door well. The method can not only improve delivery efficiency, but also avoid potential safety hazard caused by home delivery.

The invention discloses an order route system. The order route system comprises an application programming interface, an order address resolution unit, an order stock analyzing unit, a delivery analyzing unit and a transportation cost analyzing unit, wherein the application programming interface is used for catching orders submitted by a user; the order address resolution unit is used for resolving information carried by the caught orders; the order stock analyzing unit is used for detecting the available stock numbers of various articles corresponding to the orders in warehouses in real time; the delivery analyzing unit is used for determining delivery platforms meeting the order demands according to delivery address information of the orders and the order distribution ranges; the transportation cost analyzing unit is used for calculating expenditure required by the delivery platforms delivering the articles of the orders one by one for the delivery platforms meeting the order demands. The invention further provides an order route method. The system and method have the advantages of being high in delivery efficiency and accuracy and are suitable for data processing of the large-scale orders.

The invention provides an express self-service cabinet and a method of using the express self-service cabinet to manage express articles. By the aid of the express self-service cabinet, the delivery efficiency of the last mile for express can be improved greatly, an efficient managing manner is provided to property management companies, property management is facilitated, and manners for article delivery between the property management companies and owners are increased.

The invention discloses a logistics delivering system and a delivering method. The logistics delivering system comprises a logistics vehicle and express cabinets which are in butt joint for delivering packets. Multiple layers of conveying belts are arranged in the logistics vehicle from top to bottom, and multiple longitudinal conveying belts used for temporarily storing packets and transverse conveying belts connected with the longitudinal conveying belts so as to transfer the packets are arranged in each layer side by side. The rear side of the interior of a cabinet body of the express cabinet is a conveying channel, and multiple conveying belts are sequentially arranged in the conveying channel from top to bottom. Each conveying belt corresponds to one row of unit cabinets, and the side edges of the conveying belts correspond to the opening portions of the rear sides of the corresponding rows of unit cabinets. The transverse conveying belts of all the layers of the logistics vehicle are in one-to-one butt joint with the conveying belts of all the layers in the express cabinets when the logistics vehicle deliveries the packets towards the express cabinets. Position identification monitoring is conducted on the packets from sorting on a cargo allocation station to distribution to all the express cabinets from a logistics city, and the packets can be directly conveyed to the corresponding positions of the reserved express cabinets through the designated conveying belts; and the delivery efficiency and the automation degree can be improved.

The invention discloses a logistic terminal application method based on a two-dimensional code. Different from a traditional one-dimensional code which needs a special database server to store corresponding goods information, the two-dimensional code can store a large capacity of Chinese character information, and the two-dimensional code can be applied to logistics and express so as to improve delivery efficiency of a logistic and express terminal. By means of the characteristic that the two-dimensional code is large in storage capacity, text Chinese information such as a goods addressee is directly stored in the two-dimensional code. A two-dimensional code module, an intelligent mobile phone two-dimensional code recognition processing module and a computer data receiving module are included. A name, a phone number, an address and other information of the addressee are generated into the two-dimensional code to be printed on or attached to express goods. When the goods reaches the logistic and express terminal, data information is analyzed and processed by means of two-dimensional scanning and processing software, so that the functions of calling the addressee automatically, sending a short message to the addressee automatically and sending data to a computer end are achieved.

A dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment occupied by the osmotic core. The osmotic core includes an active agent composition and a light push layer. A passageway is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation. The bi-layer membrane system and the osmotic core are formulated and formed to provide controlled release of the active agent included in the active agent composition, while simultaneously facilitating increased loading of active agent within a dosage form of given dimension and increasing the delivery efficiency of such active agent relative to prior osmotic dosage forms including a push layer.

The invention relates generally to treatment of solid cancers. More particularly, a method and apparatus for efficient radiation dose delivery to a tumor is described. Preferably, radiation is delivered through an entry point into the tumor and Bragg peak energy is targeted to a distal or far side of the tumor from an ingress point. Delivering Bragg peak energy to the distal side of the tumor from the ingress point is repeated from multiple rotational directions. Beam intensity is proportional to radiation dose delivery efficiency. The multi-field irradiation process with energy levels targeting the far side of the tumor from each irradiation direction provides even and efficient charged particle radiation dose delivery to the tumor. Preferably, the charged particle therapy is timed to patient respiration via control of charged particle beam injection, acceleration, extraction, and / or targeting methods and apparatus.

The invention discloses an express cabinet and unmanned-aerial-vehicle delivery method and system based on RFID labels. The express cabinet comprises a plurality of parcel storage grids, a sorting device, a RFID reading device, a processing unit and a storage unit, wherein the multiple parcel storage grids are used for storing parcels; the sorting device is used for sorting and taking the parcels,and under control of the processing unit, a single parcel moves to the RFID reading device to read information to be sent to the corresponding parcel storage grid; the RFID reading device is used forobtaining express waybill information carried by the RFID labels on the parcels and sending the express waybill information to the processing unit; the processing unit is used for selecting free parcel storage grids according to the express waybill information and controlling the sorting device to feed the parcels into the parcel storage grids; the storage unit is used for storing information. The unmanned-aerial-vehicle delivery system comprises an unmanned aerial vehicle and the express cabinet. The express cabinet can butt joint the unmanned aerial vehicle for delivering the express parcels, the parcels delivered by the unmanned aerial vehicle are directly received, the express delivery efficiency is improved, the defects that RFID labels in the prior art are misread and low in cost are overcome, and high-efficiency and low-cost express-item accurate delivery is achieved.

The invention discloses an order intelligent scheduling method. According to the method, a lot of manual labor and operation cost of the company can be saved through control of scheduling time and the state of delivery personnel, and order processing of the same information, order processing of the same store, order processing of similar addresses, delivery capacity control of the delivery personnel and cooperative work of shortest path control so that the reasonability of scheduling can be guaranteed, and powerful support is provided for enhancing the delivery efficiency.

The invention relates generally to treatment of solid cancers. More particularly, a method and apparatus for efficient radiation dose delivery to a tumor is described. Preferably, radiation is delivered through an entry point into the tumor and Bragg peak energy is targeted to a distal or far side of the tumor from an ingress point. Delivering Bragg peak energy to the distal side of the tumor from the ingress point is repeated from multiple rotational directions. Beam intensity is proportional to radiation dose delivery efficiency. The multi-field irradiation process with energy levels targeting the far side of the tumor from each irradiation direction provides even and efficient charged particle radiation dose delivery to the tumor. Preferably, the charged particle therapy is timed to patient respiration via control of charged particle beam injection, acceleration, extraction, and / or targeting methods and apparatus.