1399 results about "Micelle" patented technology

The invention relates to the field of oil exploitation, and discloses a polymer with a heavy oil cold recovery function as well as a preparation method and application thereof. After the polymer disclosed by the invention enters a stratum, hydrophobic groups on a polymer chain can be adsorbed on an oil-water interface, the aggregation state of micelles is destroyed, the size of the micelles is greatly reduced, and released energy can provide energy required by emulsification. And meanwhile, after the amphiphilic groups are adsorbed to an oil-water interface, the tension of the oil-water interface is reduced, a low-surface-tension oil phase is automatically diffused to a high-surface-tension water phase, and spontaneous permeation emulsification viscosity reduction of the thick oil is realized without external force or under the low-power condition by virtue of the Malangori effect.

The present disclosure relates to methods, compositions and systems for droplet processing. For example, methods can include (a) providing a first emulsion comprising a first droplet population, wherein droplets of the first droplet population comprise a lysis reagent, and a second emulsion comprising a second droplet population, wherein a droplet of the second droplet population comprises i) a cell or a nucleus, and ii) a plurality of nucleic acid barcode molecules; (b) subjecting the first emulsion and second emulsion to conditions sufficient to transfer the lysis reagent to the second droplet population via micelles comprising the lysis reagent; and (c) lysing the cell or the nucleus within the droplet of the second droplet population with the lysis reagent.

The invention discloses a preparation method of an ultra-thin high-density fiberboard with ultra-low formaldehyde emission, which is characterized by comprising the following steps: peeling wood by using a peeling machine, chipping to obtain wood chips, washing the wood chips with water, cooking in a cooking cylinder, feeding into a defibrator, and adding molten paraffin for treatment to obtain fibers; meanwhile, formaldehyde is taken to be mixed with sodium bentonite, triethylene diamine and polyvinyl alcohol, then urea is added in five times, melamine is added in two times, a reaction is conducted, and melamine modified urea-formaldehyde resin is prepared; taking fibers, applying an adhesive formed by mixing melamine modified urea-formaldehyde resin, nano titanium dioxide and an ammonium chloride curing agent, drying and dehydrating the fibers uniformly mixed with the adhesive, sorting to remove micelles, fiber agglomerates and fiber bundles, and paving and forming to obtain a plate blank; and the plate blank is taken to be subjected to the hot pressing procedure to obtain a plate, and after the plate is cooled, the ultra-thin high-density fiberboard with the advantages of being high in strength, low in formaldehyde emission and the like is obtained after sanding.

The preparation method comprises the following steps: mixing polysaccharide gum with water, carrying out wet ultrafine grinding to obtain an ultrafine polysaccharide gum aqueous solution, and uniformly infiltrating the polysaccharide gum into cellulose or derivatives thereof by adopting high-shear mixing to form micelles; and promoting the micelles to form a honeycomb structure through microwave vacuum drying, and finally spraying ultrapure water atomized by high pressure to the honeycomb micelles and drying to obtain the hydrogel for absorbing grease. The water absorption capacity of the prepared hydrogel reaches 100 times or above, the storage modulus is 1350 Pa or above, grease can be efficiently absorbed, and the hydrogel has wide development prospects in the field of weight-reducing medicine or food.

The invention relates to hydrogel for treating ischemic brain injury and a preparation method thereof. The hydrogel is prepared from the following raw materials: methylacryloylated hyaluronic acid, methylacryloylated gelatin, curcumin loaded HA-PPS (Hydroxypropyl-Polyphenylene Sulfite) nano-micelles and dendrobium polysaccharide loaded sodium alginate microspheres. Through combination of a nanotechnology and an intelligent response material, HA-PPS is adopted to load curcumin and sodium alginate microspheres are adopted to encapsulate dendrobium polysaccharide, so that the drug activity can be more effectively protected, the drug is protected to penetrate through a blood brain barrier and be accurately delivered to a brain injury area, and targeted release of the drug is realized; the anti-oxidation and anti-inflammatory effects are better under the combined action of the curcumin and the dendrobium polysaccharides, and meanwhile, a slow release function is also achieved.

A preparation method of a double-network versatile hydrogel with antibacterial and drug sequential release capabilities is provided in the present disclosure, belonging to the technical field of biological corneas. The preparation method includes the following steps: mixing filipin protein-methacrylate, glycidyl methacrylate functionalized quaternized chitosan, polydeoxyribonucleotide, and lithium phenyl(2,4,6-trimethylbenzoyl) phosphinate with drug-loaded micelles, followed by cross-linking under irradiation of ultraviolet to construct a double-network versatile hydrogel with antibacterial and drug sequential release capabilities.

The invention relates to an anti-oxidation composition based on a reverse micelle synergistic technology and a preparation method and application thereof, the anti-oxidation composition comprises a reverse micelle structure and an aqueous solution containing an anti-oxidation active matter, and the reverse micelle structure wraps the aqueous solution containing the anti-oxidation active matter. The reverse micelle structure is used for wrapping the water-soluble antioxidant active matter, oxidation or degradation discoloration of the water-soluble antioxidant active matter is prevented, after the antioxidant active matter such as hydroxytyrosol, ergothioneine and dipotassium glycyrrhizinate is wrapped by the reverse micelle, the stability and the effect are remarkably improved, and after the reverse micelle wrapping, the effect of the antioxidant active matter is improved by 17% or above compared with an aqueous solution before wrapping.

The invention belongs to the field of nano material preparation, and particularly relates to a preparation method of nanoscale silicon dioxide alcohol-soluble sol. The method comprises the following steps: dissolving a water-soluble polymer in an ammonia water solution, and then adding absolute ethyl alcohol to form a polymer micelle; adding tetraethyl orthosilicate into the micelles, obtaining a nanoscale silicon dioxide nanoparticle mixed solution after the reaction is finished, then dispersing the nanoscale silicon dioxide nanoparticle mixed solution in deionized water through centrifugation, then centrifuging to obtain pure silicon dioxide particles, dispersing the pure silicon dioxide particles in absolute ethyl alcohol, adding a silane coupling agent KH570 at the same time, and performing ultrasonic dispersion to obtain the nanometer silicon dioxide nanoparticles. And carrying out ultrasonic dispersion to obtain the nanoscale silicon dioxide alcohol-soluble sol.

The invention relates to the field of cosmetics, and relates to a collagen-containing cosmetic, in particular to application of a reverse micelle carrier in preparation of a cosmetic for improving collagen intradermal retention volume. The cosmetic comprises a collagen composite raw material, the collagen composite raw material comprises the following components in percentage by mass: 53.55-80% of grease; 15 to 60 percent of phospholipid; 0.5 to 1.5 percent of an antioxidant; 0.1 to 2 percent of water; and 0.01% to 0.5% of collagen; the grease is prepared from any one of isopropyl myristate, isopropyl laurate or isopropyl acetate; the phospholipid comprises lecithin, and the purity of the lecithin is 90% or above. The retention amount of the collagen in the cosmetic containing the collagen in the skin can be increased, so that the collagen permeates into the skin epidermis or dermis and accumulates in the skin layer; the real collagen supplementing effect of cosmetics is greatly improved, and the skin young state is facilitated.

The invention belongs to the technical field of biomedical materials, and discloses injectable heterogeneous cascade nano-enzyme antibacterial hydrogel as well as a preparation method and application thereof. The preparation method comprises the following steps: in a process of preparing cerium dioxide nano-enzyme by a reverse micelle method, introducing molybdenum disulfide nano-particles with a nano flower-shaped structure so as to deposit the cerium dioxide nano-enzyme on the surfaces of the molybdenum disulfide nano-particles in situ to obtain nano-composite particles; through electrostatic interaction, glucose oxidase is loaded on the surfaces of the nano composite particles to form a heterogeneous cascade nano enzyme material; the preparation method comprises the following steps: uniformly mixing sodium alginate and hyaluronic acid in water, and sequentially adding an NO donor, a heterogeneous cascade nano-enzyme material and a cross-linking agent to obtain the injectable heterogeneous cascade nano-enzyme antibacterial hydrogel. The preparation method is simple, and the injectable heterogeneous cascade nano-enzyme antibacterial hydrogel has a strong antibacterial effect and can be used for preparing the antibacterial hydrogel. Particularly, the compound has a remarkable killing effect on gram-negative bacteria and gram-positive bacteria.

The invention relates to an aloe extract nano-vesicle as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The aloe extract nano-vesicle provided by the invention is a nano-micelle formed by an aloe extract and tocopheryl acetate, the particle size of the aloe extract nano-vesicle is 280 to 500 nm, the Zeta potential of the aloe extract nano-vesicle is-10.12 to-11.34 mV, and the polydispersity coefficient of the aloe extract nano-vesicle is 0.239 to 0.434. The aloe extract nano-vesicle disclosed by the invention has a nano-scale size, and can easily penetrate through a skin barrier and enter skin cells, so that the moisturizing effect of the aloe extract nano-vesicle is achieved. The permeability of the moisturizing composition is far better than that of the traditional moisturizing composition, so that the required moisture can be more effectively provided for the skin. The aloe extract nano-vesicle can carry other active ingredients such as moisturizing factors to deeply permeate into skin, comprehensive care is provided for the skin, the texture and appearance of the skin are improved, the preparation process is simple, and the aloe extract nano-vesicle is suitable for technological production.

The invention relates to the technical field of biological medicine, in particular to a ferroptosis inhibition type phospholipid-like material and application thereof. The ferroptosis inhibition type phospholipid-like material is one of the following structural general formulas (1)-(5). The biomimetic phospholipid-like ferroptosis inhibitor has a long retention characteristic in main positions (cell membranes, endoplasmic reticulum and other organelle membranes) of cell ferroptosis, so that the ferroptosis inhibition efficiency is remarkably improved. The novel phospholipid-like material not only can be used as an active drug molecule, but also can be used as a pharmaceutic adjuvant for constructing drug delivery carriers such as lipidosome and micelle and implant coatings, and is suitable for various administration routes such as oral administration, injection and local administration. The novel biomimetic ferroptosis inhibitor can efficiently relieve cell ferroptosis and has a wide application prospect in the field of treating or retarding ferroptosis-related diseases.

The invention belongs to the technical field of biomedical high-molecular polymer materials, and discloses a pH and temperature dual-response lignin-based amphiphilic polymer and micelle as well as a preparation method and an application of the pH and temperature dual-response lignin-based amphiphilic polymer and micelle. The preparation method of the polymer comprises the following steps: purifying the alkali lignin, preparing a macroinitiator AL-Br based on the alkali lignin, and then preparing the lignin-based amphiphilic polymer with double responses of pH and temperature. The polymerization process is controllable, and the usage amount of copper is lower than 500 ppm. The lignin polymer disclosed by the invention can be self-assembled into nano-scale micelles in a water medium, the structure is stable, and AgNPs and an entrapped hydrophobic anticancer drug CPT can be simultaneously prepared in situ. The obtained single nano-carrier system has good silver nanoparticle stabilizing capacity, in-vitro pH and temperature double-response drug release capacity and excellent cytotoxicity and antibacterial capacity, can achieve the anti-tumor and antibacterial purposes at the same time, and is well applied to preparation of drugs with anti-tumor and antibacterial effects at the same time.

The present disclosure provides micelles comprising a plurality of block co-polymers, the micelle comprising (i) a core comprising at least a portion of a poly(alkyl acrylate) block of one or more of the block co-polymers; and (ii) an outer layer comprising at least a portion of a poly(aryl acrylate) block or a poly(aryl methacrylate) block of one or more of the block co-polymers. The present disclosure also includes polymer compositions, polymer films, and devices (e.g., orthodontic equipment) including the same. Methods for making and using micelles, polymer compositions, polymer films, and devices (e.g., orthodontic equipment) are also disclosed. Further provided herein are methods of producing polymer compositions and using the same for the fabrication (e.g., via 3D printing) of medical devices, such as orthodontic appliances.

The invention relates to the technical field of lubricating oil, in particular to anti-wear and anti-attrition composite lubricating oil and a preparation method and application thereof. The anti-wear and anti-attrition composite lubricating oil is prepared from the following raw materials: base oil, an anti-wear reagent at extreme pressure, a preservative, an antioxidant, a viscosity index improver and a dispersing agent, the extreme pressure anti-wear agent is obtained by modifying layered molybdenum oxide with metal micelles formed by dodecylamine and wet and then carrying out hydrothermal treatment and vulcanization. The prepared anti-wear and anti-attrition composite lubricating oil has excellent anti-wear and anti-attrition effects and extreme pressure properties, is suitable for the lubrication requirements under high load and harsh conditions, and has a wide application prospect.

The invention discloses high-strength hydrogel with high Tlum and delta Tsol and adjustable tau c as well as a preparation method and application of the high-strength hydrogel. The hydrogel disclosed by the invention is obtained by copolymerizing raw materials including a hydrophobic monomer and a hydrophilic monomer, wherein the hydrophobic monomer is a hydrophobic monomer containing a polyether structure; the hydrophilic monomer is a monomer containing at least one hydrophilic group of carboxyl, hydroxyl and amino. The hydrogel provided by the invention is obtained by copolymerization of a hydrophobic monomer and a hydrophilic monomer, wherein the side chain of the hydrophobic monomer contains a polyether structure. Wherein hydrophobic polyethylene glycol side groups in the hydrogel are self-assembled to form micelles, the micelles are uniform and transparent and have very good light transmittance before the phase change temperature, phase separation occurs when the temperature exceeds tau c to form a polymer-rich phase and a water-rich phase, light is scattered between the two phases, the light transmittance of the hydrogel is greatly reduced, and the light transmittance of the hydrogel is greatly improved. Therefore, the solar cell has excellent thermochromism capability, and the sunlight modulation capability is effectively improved.

The invention discloses an ultrashort-sequence antibacterial peptide rich in lysine and tryptophan, an antibacterial peptide hydrogel and application of the ultrashort-sequence antibacterial peptide and the antibacterial peptide hydrogel. The preparation method comprises the following steps: combining lysine and tryptophan to obtain polypeptide containing five or six amino acids; then amidation is carried out on the C terminal of the polypeptide, fatty acid chain modification is carried out on the N terminal and side chain amino groups, the ultra-short sequence antibacterial peptide rich in lysine and tryptophan is obtained, and the antibacterial peptide has broad-spectrum antibacterial activity for resisting gram-positive and gram-negative bacteria. An antibacterial peptide micelle self-assembly experiment shows that C12-2KW can be self-assembled into stable hydrogel in a 7.17 mu M PBS (Phosphate Buffer Solution), the hydrogel internally has a compact net-shaped structure, can completely cover the peritoneal injury surface and physically isolate the peritoneal injury surface from surrounding tissues, and has a good effect on treating wound infection caused by MRSA (Methicillin-Resistant Staphylococcus Aureus); meanwhile, the compound has the effect of resisting intestinal wall and abdominal wall adhesion after an operation, is low in toxicity, has a very good application prospect in the aspect of preparing clinical antibacterial drugs, and is expected to become a candidate drug of a novel antibiotic.

The invention discloses a composite solvent for removing organic sulfur in industrial synthesis gas and a preparation method thereof, and belongs to the technical field of separation and purification, the composite solvent comprises 40-60 parts of a main desulfurizer, 8-12 parts of a dynamic modifier, 5-15 parts of a mass transfer enhancer, 20-30 parts of a temperature-sensitive phase change skeleton and 8-14 parts of an auxiliary agent, and the auxiliary agent comprises an antioxidant, a corrosion inhibitor and a polar mixed solution. According to the present invention, the multistage pore channel micelle structure of the introduced mass transfer reinforcing agent provides the rich and efficient transmission channel for the diffusion of the sulfide, such that the diffusion rate of the sulfide penetrating the ionic liquid layer is substantially accelerated, and the liquid phase mass transfer coefficient is effectively improved; the core principle is that the diffusion path of sulfide molecules in the ionic liquid environment is optimized, the mass transfer bottleneck caused by high viscosity of the traditional ionic liquid is broken through, and excessive accumulation of the sulfide molecules on the surface of an ionic liquid layer due to mass transfer obstacle is avoided, so that the desulfurization efficiency is remarkably improved; the problem of slow mass transfer caused by high viscosity of the ionic liquid in the prior art is solved.

The invention relates to the technical field of oral membranes, in particular to a multilayer oral membrane and a preparation method thereof. The invention provides an oral membrane composition, which comprises semeglutide and pharmaceutically acceptable auxiliary materials, and is characterized in that the composition is formed by combining a drug-containing biological adhesion layer and a backing layer, and the backing layer mainly comprises a membrane forming material, a solvent and a plasticizer; the drug-containing biological adhesion layer mainly comprises semeglutide, a film-forming material, an adhesive, a pH regulator, a flavoring agent and a solvent. By preparing the double-layer oral membrane, the semeglutide is administrated through the oral cavity, and after the insoluble or slowly eroded / dissolved backing layer (preventing saliva from dissolving the medicine) and the adhesive layer containing the main medicine are combined together, the one-way delivery of the main medicine can be realized; through experiments, it is accidentally found that when temperature-sensitive materials such as poloxamer are added to be combined with a conventional adhesive for use, the residence time of the medicine in the oral mucosa can be remarkably prolonged, the curative effect of the medicine is improved, and the main mechanism is that after the medicine is administered, in the oral temperature environment, after the medicine makes contact with mucus on the surface of the oral mucosa, the oral mucosa does not adhere to the oral mucosa. And after the entanglement and piling effects among poloxamer micelles are intensified to form gel, the gel and a conventional adhesive are cooperated to improve the adhesion between the oral membrane and the oral mucosa. Besides, the medicine can be removed at any time, blood sugar can be better controlled, T2DM complications can be better reduced, a more ideal taking mode is provided for weight loss patients, and a new administration mode is provided for reducing blood sugar and reducing weight. The prepared oral cavity membrane is small in size, light in weight, thin, convenient to apply, carry and transport, safe and environmentally friendly to use and capable of meeting the requirements of old people and travelers.

The invention is applicable to the technical field of mesoporous materials, and relates to an ultra-small single-mesoporous carbon nanoparticle and a preparation method and application thereof. The preparation method comprises the following steps: (1) preparing a single micelle solution; (2) obtaining SiO2 nano particles; (3) obtaining the SiO2 (at) single micelle superstructure nano particles; (4) obtaining a compound of the SiO2 coated single micelle wrapped by the polydopamine; (5) obtaining a SiO2-loaded mesoporous carbon structure; the invention also discloses an application of the ultra-small single mesoporous carbon nanoparticles in a battery. The ultra-small single-mesoporous carbon nanoparticles and the preparation method thereof have the beneficial effects that the single-mesoporous carbon nanoparticles have a large specific surface area, ultra-small particle size, large aperture and a unique broken hole structure, active sites of chemical reaction are increased, a better substance transmission channel can be provided, potential safety hazards are reduced, and the service life of the single-mesoporous carbon nanoparticles is prolonged. And the assembled aqueous zinc ion battery has relatively high discharge specific capacity.

The invention discloses a high molecular weight poly (p-dioxanone) (PPDO) microsphere as well as a preparation method and application thereof. By adopting a double emulsification-solvent evaporation method, an amphiphilic polymer, such as poly (p-dioxanone) (PDO) or a copolymer of PDO and a hydrophilic fragment (such as mPEG and mPPG), is utilized to perform self-assembly on a two-phase interface formed by emulsification under the combined action of amphipathy and polyvinyl alcohol (PVA) to form a double-micelle protective layer, so that the degradation effect of water on PPDO in the microsphere forming process is effectively blocked, and the PPDO can be effectively degraded. And finally, the high-molecular-weight poly (p-dioxanone) microspheres with stable performance are obtained, so that the high-molecular-weight PPDO microspheres have long-term stability. The preparation method is high in operability, mild in condition and suitable for large-scale production, high-molecular-weight poly (p-dioxanone) microspheres are obtained, and the preparation method has wide application prospects in the aspects of tissue filling agents, drug carriers, tissue scaffolds and the like.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses a cyclophosphamide ternary nano-micelle and a preparation method thereof.The cyclophosphamide ternary nano-micelle prepared through the method can be used for treating malignant lymphoma, multiple myeloma, leukemia, breast cancer, ovarian cancer, cervical cancer, prostatic cancer, colon cancer, bronchial cancer, lung cancer and the like. Reasonable preparation steps and a preparation formula are adopted, the use of an organic reagent is reduced, the irritation of cyclophosphamide is reduced and the stability of the micelle is improved by adjusting a freeze-drying technology, and the cyclophosphamide micelle adopts amphiphilic macromolecules as a carrier material, so that the drug loading capacity and the stability of the micelle are obviously improved, and the bioavailability of the micelle is improved. The ternary nano-micelle system has the advantages that the solubility of cyclophosphamide is improved, the in-vivo bioavailability is increased, the preparation method is simple, the micelle performance is stable, and large-scale industrial production is facilitated.

The invention provides a lipidosome STING agonist delivery system based on a PD-L1 antibody as well as a preparation method and application of the lipidosome STING agonist delivery system, and belongs to the technical field of medical biology. Preparing lipidosome by adopting an ethanol injection method and an ammonium sulfate gradient technology; the PD-L1 antibody and the STING agonist can be loaded at the same time; the liposome is prepared by adopting an ethanol injection method and an ammonium sulfate gradient technology, and the STING agonist can be wrapped in the liposome in an active drug loading manner; dSPE-PEG2000-NHS and a PD-L1 antibody are mixed and incubated according to a specific proportion by utilizing a post-insertion method to form an antibody conjugated micelle, and the antibody conjugated micelle is fused with a blank liposome to realize antibody modification; secondly, the nano-liposome has good drug carrier characteristics and can effectively protect the loaded drug, reduce the risk of enzymolysis of the drug and improve the stability of the drug in vivo, so that the liposome drug delivery system simultaneously loading the nano-liposome and the nano-liposome is successfully prepared.

The present invention addresses the problem of providing a novel transparent cleaning agent having high cleaning power and excellent long-term stability even when containing water. The transparent cleaning agent for solving the problem of the present invention is characterized by being of a water-containing reverse micelle type containing the following components (A) to (F). (A) an ester of a fatty acid having 8-10 carbon atoms and a polyglycerol; (B) an ester of a branched fatty acid having 14-22 carbon atoms and / or an unsaturated fatty acid and a polyglycerol; (C) an aliphatic alcohol and / or fatty acid that is liquid at 25 DEG C; (D) an oil agent (excluding component (C)) containing a hydrocarbon oil; (E) more than 0% and 10% by mass or less of water; and (F) a polyol.

This invention provides an environmentally friendly expandable polystyrene bead and its preparation process, belonging to the field of foaming material technology. The preparation process includes the following steps: S1, injecting 65.28g of deionized water into a reaction vessel, stirring, adding 0.13g of dispersant and 0.16g of composite stabilizer, dispersing for 20min, then adding 31.95g of styrene monomer and 0.3g of composite initiator, followed by the addition of pentane and SiO2 micelle composite to obtain a base solution; wherein the mass ratio of pentane to SiO2 micelle composite is 1:(0.2-0.3); the mass of pentane is 3.1%-3.2% of the mass of the base solution; S2, subjecting the base solution to stepwise heating at 86℃-140℃ with stirring, then stopping heating, continuing stirring, and allowing it to cool naturally to 40℃, then stopping stirring, with a total reaction time of 8.5-9.5h to obtain the reaction product; S3, discharging the material, washing the reaction product with warm water, filtering, and obtaining the environmentally friendly expandable polystyrene beads. This invention improves the average particle size of expandable polystyrene beads while reducing fine powder.

The present invention relates to the technical field of oilfield chemistry, and provides a wormlike supramolecular associated micelle, a hydrophobic associated copolymer and a preparation method thereof, the wormlike supramolecular associated micelle comprises a soft template, a hydrophobic functional monomer 1, a hydrophobic functional monomer 2 and a polarity regulator, the soft template is a long-chain molecular polymer and has an active functional group, and the polarity regulator is a hydrophobic functional monomer 2. The hydrophobic functional monomer 1 is an anionic-nonionic surfactant with polymerizable double bonds, the hydrophobic functional monomer 2 is a cationic-nonionic surfactant with polymerizable double bonds, and the polarity regulator is a micromolecular organic compound. The problems of poor resistance reduction, sand carrying capacity and the like of the fracturing fluid in the construction process due to dissociation of a polymer molecular network structure and sudden reduction of rheological property and viscoelasticity are solved.

The invention discloses a fruit and vegetable extract extraction method combined with ultrasonic enhancement, and particularly relates to the field of fruit and vegetable extract extraction.The fruit and vegetable extract extraction method comprises the steps that a composite micelle structure formed by saccharides and functional factors in fruit and vegetable raw materials is recognized as a structure obstacle before extraction, and a directional unbinding path is constructed according to the binding configuration and structural responsiveness of the structure obstacle; to generate a group of ultrasonically extracted target components; and constructing an ultrasonic cooperative transmission path with continuous penetrability and cavitation energy focusing capability by taking the sound response condition and the foam interference characteristic of the liquid phase environment in which the target component group is located as dynamic parameters. By constructing a multi-dimensional synergistic extraction process of a sugar-phenol deconstruction path, a cavitation energy penetration path and a migration enrichment feedback path, the problems of low functional component release efficiency and difficult purity control caused by superposition of a wrapping effect and an acoustic resistance barrier in a high-sugar system are solved.

The invention belongs to the technical field of veterinary medicine preparation, and particularly relates to a preparation method of a scutellaria baicalensis stem and leaf extract preparation. The preparation method of the scutellaria baicalensis stem and leaf extract preparation comprises the following steps: performing alcohol extraction on scutellaria baicalensis stems and leaves to obtain an alcohol extract; and uniformly mixing the alcohol extract and the lauryl sodium sulfate / polyethylene glycol-6000 mixture to obtain the scutellaria baicalensis stem and leaf extract preparation. According to the preparation method, lauryl sodium sulfate and polyethylene glycol-6000 are jointly added into a scutellaria baicalensis stem and leaf extract obtained through an alcohol extraction method, and the scutellaria baicalensis stem and leaf extract preparation is prepared from the scutellaria baicalensis stem and leaf extract. Due to the solubilizing characteristic of the lauryl sodium sulfate and the polyethylene glycol-6000, the lauryl sodium sulfate and the polyethylene glycol-6000 are dissolved in water and then gather in water to form micelles, the scutellaria baicalensis stem and leaf extract which is insoluble in water can be wrapped in a micelle core through the method, and the solubility of the scutellaria baicalensis stem and leaf extract is further improved.

The invention discloses a novel process for producing a high-quality liquid fertilizer by using an acetylisovaleryltylosin tartrate finished product liquid, and relates to the technical field of fertilizer preparation, and the novel process comprises the following specific steps: step 1, firstly, weighing polyoxyethylene sorbitan fatty acid ester, ethylenediamine tetraacetic acid disodium salt, cellulase and protease, and uniformly stirring; the preparation method has the advantages that the polylactic acid-glycolic acid copolymer serving as a functional high-molecular polymer has good biocompatibility and controlled release performance, and when a solution prepared from the polylactic acid-glycolic acid copolymer is emulsified and mixed with an alginate oligosaccharide solution, a uniform emulsion-like active synergistic carrier solution is formed; the emulsifying and mixing process enables the effective components in the two solutions to be fully and uniformly combined together to form a stable microsphere and micelle structure, so that the continuous and slow release of the acetylisovaleryltylosin tartrate and the synergistic plant growth regulatory factors thereof in the growth cycle of crops can be ensured, the fertilizer effect of the acetylisovaleryltylosin tartrate and the synergistic plant growth regulatory factors thereof can be fully exerted, and the crop quality is improved. Therefore, the problem that the fertilizer efficiency is not obvious in the prior art is effectively solved.

The invention discloses emblic leafflower fruit polysaccharide with sugar-controlling and lipid-lowering activity as well as a preparation method and application of the emblic leafflower fruit polysaccharide. The polysaccharide is prepared by taking fresh phyllanthus emblica pulp as a raw material through hot water extraction, yeast fermentation, desorption after XAD-16 macroporous resin adsorption, alcohol precipitation, ultrafiltration and DEAE-52 cellulose column purification. The low-molecular-weight gulcomannan is separated from phyllanthus emblica for the first time, and monosaccharide composition of the gulcomannan mainly comprises glucose, mannose and galactose and contains trace rhamnose and xylose. The polysaccharide has sugar-controlling and lipid-lowering active action targets in the whole digestive tract (the upper digestive tract: glycolipid digestion and absorption enzymes alpha-amylase, alpha-glucosidase and pancreatic lipase inhibitory activity, starch hydrolysis delay, bile acid adsorption capacity and cholesterol micelle dissolution inhibition capacity; in the lower digestive tract, the multiplication promoting capacity of glycolipid metabolism-related probiotics) shows extremely high biological activity, and can be applied to food and health care products.