490 results about "Oleic Acid Triglyceride" patented technology

This invention discloses a method for preparing low-GI special dietary noodles, belonging to the field of special dietary food development. This invention screens negatively charged dietary polysaccharides and constructs a tightly packed quaternary network structure based on amylose, oleic acid, protein, and dietary polysaccharides. It prepares an amylose-oleic acid complex (complex 1) and a complex 1-protein ternary network (complex 2) stepwise, and then regulates the cooking process to form a complex 2-dietary polysaccharide quaternary network (complex). This invention significantly reduces the GI value of the noodles and improves their texture.

The invention discloses a horse milk-derived small molecule peptide, the amino acid sequence of which is Met-Ser-Pro-Phe (MSPF), and the molecular weight of which is 480.571 Da. The small molecule peptide disclosed by the invention has the activity of inhibiting pancreatic lipase (PL), the inhibition rate on the pancreatic lipase is 61.44%, and the accumulation of the content of triglyceride (TG) in oleic acid-induced human liver cancer (HepG2) cells can be reduced, so that the small molecule peptide can be used for inhibiting the pancreatic lipase (PL). The small molecule peptide can be applied to preparation of preparations for treating or assisting in treating hyperlipidemia and obese people, is simple to prepare, and is suitable for industrial production and market popularization and application.

The invention relates to the technical field of physical property analysis, in particular to a rapeseed oil quality detection method and device and a storage medium. Determining Raman spectrum data of the rapeseed oil sample based on the oleic acid concentration and the erucic acid concentration; determining a peak intensity contribution coefficient based on the Raman spectrum data; based on the oleic acid concentration, the erucic acid concentration and the peak intensity contribution coefficient, constructing a rapeseed oil quality detection model; and performing quality detection on Raman peak characteristics of to-be-predicted rapeseed oil based on the rapeseed oil quality detection model to obtain a detection result of the to-be-predicted rapeseed oil. According to the method, the prediction precision of the rapeseed oil quality is improved.

The invention relates to a high-performance reactive asphalt cold patch mixture and a preparation process thereof. The mixture comprises a sulfonated fatty acid diluent, a graded aggregate, an atomic layer deposition (ALD) modified basalt aggregate and a solid waste-based composite curing agent. The sulfonated fatty acid diluent is prepared by sulfonating oleic acid, linoleic acid and palmitic acid through sulfamic acid, the sulfonation degree is 15-20%, and the sulfonated fatty acid diluent contains an epoxy three-membered ring structure; the 3-5mm aggregate is used as a transition layer to block the caking path of the fine aggregate; the basalt aggregate is subjected to TDMAT and TMA alternate deposition to form a Ti < x > Al < gamma > O < 2 > nano film; the curing agent comprises calcium strontium sulphoaluminate minerals, a titanium gypsum-carbide slag compound and magnesium-loaded lithium slag. During preparation, the modified aggregate, the sulfonated diluent and the curing agent are mixed at normal temperature. The problems that a traditional cold repairing material is poor in low-temperature fluidity and weak in interface bonding are solved, the viscosity at-20 DEG C is smaller than or equal to 450 mPa.s, the 7-day strength is larger than or equal to 5.2 kN, and the cold repairing material is suitable for low-temperature emergency repairing.

Disclosed herein is a method for producing a lipid or oil in a plant, the method comprising genetically modifying the plant to express a plurality of heterologous proteins selected from PaWRI1, PaWRI2, PaDGAT1, or PaPDAT1, or variants thereof. The expression of the plurality of heterologous proteins in the genetically modified plant may result in a change in the nutrient profile of the plant relative to non-genetically modified plants of the same species. Also disclosed herein is a method for producing fatty acid and triacylglycerol content in plant non-seed tissue. Further disclosed herein is a method for producing a genetically modified plant.

The present application relates to the technical field of peanut oil extraction, and particularly relates to a method for extracting peanut oil with high oleic acid and original flavor, comprising the following steps: S1, screening: screening the peanut raw material subjected to peeling treatment by using a vibrating screening device to screen out impurities in the peanut raw material, so as to obtain peanut raw material; S2, pretreatment: sequentially subjecting the screened peanut raw material to three-stage low-temperature gradient drying, and using infrared auxiliary dehydration, and controlling the total water content at 3%-4%; the method for extracting peanut oil with high oleic acid and original flavor, by adding starch-chitosan composite liquid, the starch-chitosan composite liquid is compounded by natural ingredients and strengthened by nano structure, realizing multiple functions of antioxidation, bacteriostasis and physical barrier, while retaining the original flavor of peanut oil, significantly improving the stability of oleic acid, and having clear technical effect and industrialization potential.

The invention provides low-viscosity high-wear-resistance vehicle engine oil and a preparation method thereof, and belongs to the technical field of engine oil. According to the preparation method, an ionic liquid group is introduced through a reaction, a nano interlayer compound is constructed by combining surface modification of a metal-ionic liquid complex and silicon dioxide nanoparticles, and a microcapsule structure is formed through coating of a urea-formaldehyde prepolymer; the ionic liquid group provides a low friction coefficient and thermal stability, the silicon dioxide nanoparticles provide physical isolation and wear-resistant protection, and the microcapsules realize controlled release and dynamic repair of the lubricating components; a skeleton polymer is prepared through a reaction of polyamidoamine and epoxy chloropropane so as to provide abundant active sites, and oxidation resistance is improved through a synergistic effect of the skeleton polymer, hindered phenol and calixarene; by combining oleic acid modified nanoparticles, the dispersity and the wear resistance are enhanced, and meanwhile, dynamic protection is provided on a friction interface; the synergistic effect prolongs the service life of the engine oil and improves the high-temperature stability of the engine oil.

The invention relates to the technical field of nutritional foods, and particularly discloses a nutritional composition for improving muscle functions and application. The nutritional composition for improving the muscle function, provided by the invention, is prepared from the following components in parts by mass: 40 to 60 parts of 1, 3-dioleic acid-2-palmitic acid triglyceride and 20 to 70 parts of 1-oleic acid-2-palmitic acid-3-linoleic acid triglyceride. A specific amount of OPO and OPL are compounded, and the two components have a synergistic effect, so that the exercise amount and the ATP content of an organism are remarkably increased, sarcopenia is relieved by improving energy metabolism, the muscle function is improved, and the food has a wide application prospect in the field of food and is worthy of popularization and application. The food can be used in health-care food, formula food for special medical purposes, infant formula food or special diet food.

The invention discloses a preparation method of bio-based modified silicone oil, which comprises the following steps: uniformly mixing vegetable fat, allyl polyether and siloxane, heating to 100-120 DEG C, adding a catalyst, and reacting while stirring to obtain the bio-based modified silicone oil, the vegetable fat is selected from one or more of vegetable oleic acid methyl ester to vegetable oleic acid decyl ester. According to the bio-based modified silicone oil disclosed by the invention, conventional silicone oil is modified by adopting vegetable fat, so that the environment-friendly performance is improved, and meanwhile, the bio-based modified silicone oil is applied to a polyurethane material, and the related performance of the polyurethane material can be effectively improved; meanwhile, the allyl polyether is added, so that the compatibility and the stability of the system can be further improved.

This invention provides a safe, environmentally friendly and solvent free method for dispersing graphene into polymeric compositions. In this process solid particles of graphene in a fatty acid matrix are mixed into the polymeric composition. The use of these solid graphene containing particles does not create dust while being mixed into the polymer and can much more easily be mixed into the polymer. Since fatty acids, such as stearic acid, palmitic acid, and oleic acid, are frequently incorporated into the polymeric formulations used in making a wide variety of products, this technique also offers a good method for introducing the fatty acid into the polymeric formulation. In such fatty acid containing polymeric formulations this technique also offers the advantage of not introducing unwanted solvents or agents into the formulation.

The present application belongs to the technical field of polyester oil agent, and particularly relates to a smoothing agent for polyester FDY spinning oil agent. The smoothing agent for polyester FDY spinning oil agent comprises the following components in parts by weight: 20-30 parts of fatty acid ester; 15-20 parts of polyether modified oleic acid; and 10-15 parts of modified amino silicone oil. The smoothing agent provided by the present application comprises the components of fatty acid ester, polyether modified oleic acid and modified amino silicone oil, the polyether modified oleic acid and the modified amino silicone oil help to improve the comprehensive performance of the smoothing agent, endow the smoothing agent with excellent smoothness, wettability and high-temperature resistance, and are used in the polyester FDY oil agent, have high oil film strength, can also improve the antistatic performance and the flame retardant performance of the oil agent, and are suitable for being specially used in flame-retardant polyester fully drawn yarn oil agent.

The invention discloses a preparation method of fermented peony seed oil. The fermentation process is optimized, different strains such as lactic acid bacteria, saccharomycetes and bifidobacteria are innovatively combined for multiple times of fermentation, and the lactic acid bacteria and saccharomycetes mixed strains are used for primary fermentation, so that components are preliminarily decomposed, and the viscosity is reduced; a bifidobacterium strain is used for secondary fermentation, so that the components are further optimized. After fermentation, supercritical CO2 extraction and freezing purification are performed to obtain the high-quality peony seed oil. According to the process, the content of monounsaturated fatty acid oleic acid in the peony seed oil is increased to 80.06%, the content of polyunsaturated fatty acid linoleic acid and linolenic acid is reduced, the product stability is improved, the skin feeling is fresh and cool when the peony seed oil is used, the permeation rate is increased, the DPPH free radical scavenging rate is increased, and the peony seed oil has an anti-eczema effect.

The invention belongs to the technical field of lubricating oil manufacturing, and relates to composite lubricating oil used in an aluminum rolling process, which comprises the following components in parts by mass: 94-96 parts of base oil, 0.5-1.5 parts of an oiliness agent, 0.5-0.8 part of an extreme pressure anti-wear agent, 0.5-1.5 parts of a wear-resistant antioxidant, 0.5-2 parts of oleic acid diethanolamide and 0.5-1 part of an antirust agent. On the basis of the prior art, nano-sheet molybdenum disulfide is introduced and added into 2-aminoterephthalic acid and nickel nitrate to react to prepare a modified metal organic framework, then carnosic acid is grafted through an amide reaction to prepare the wear-resistant antioxidant, and a protective film can be formed on a friction interface through a sheet structure of molybdenum disulfide, so that the friction coefficient is reduced; the wear resistance is improved; a compact passive film is formed on the surface of aluminum metal through the synergistic effect of the extreme pressure anti-wear agent and the wear-resistant antioxidant, and the corrosion resistance and wear resistance of the composite lubricating oil used in aluminum plate rolling are improved.

The invention relates to the technical field of flotation, and discloses a spodumene flotation reagent and a preparation method thereof, and the spodumene flotation reagent comprises sulfonated oleic acid, phosphonic acid modified oleic acid hydroximic acid, peroxyoleic acid soap, fatty acid polyoxyethylene ether, polyether amine and an alcohol compound. According to the flotation reagent provided by the invention, the phosphonic acid modified oleic hydroximic acid is introduced, so that the phosphonic acid modified oleic hydroximic acid and spodumene can form a stable chelate on the basis of retaining the collecting property of carboxylic acid groups, and the problem of poor selectivity caused by single addition of oleic acid can be avoided; and by introducing sulfonated oleic acid, fatty acid polyoxyethylene ether and polyether amine, the collecting capacity of metal ions on the surface of spodumene can be enhanced, and flotation is facilitated.

The invention discloses a nanometer emulsion based on a citrus extract and a preparation method of the nanometer emulsion. The nano-emulsion takes citrus pectin as a main chain, gallic acid, ascorbic acid-phosphate and oleic acid are sequentially grafted, the oleic acid is lipophilic, the rest is hydrophilic, and the amphiphilic pectin can form the whitening nano-emulsion which can be stably stored for a long time. The natural citrus extract is used for replacing traditional synthetic components, has the anti-oxidation, whitening and anti-inflammatory effects, can reduce the skin sensitivity risk, and conforms to the green beauty makeup trend; meanwhile, the oil phase is anchored by a hydrophobic block, steric hindrance is formed by a hydrophilic block, the stability of the emulsion is remarkably improved, and the shelf life is prolonged to 24 months; phenolic acid and ascorbic acid contained in the traditional Chinese medicine composition can effectively scavenge free radicals, inhibit tyrosinase activity, reduce melanogenesis and reduce release of a proinflammatory factor IL-6; the composition is low in cost, environment-friendly, suitable for the fields of cosmetics and medicines and wide in market prospect.

The invention belongs to the technical field of polyester oil, and particularly relates to a smoothing agent for polyester FDY spinning oil. The smoothing agent for the polyester FDY spinning oil comprises the following components in parts by weight: 20-30 parts of fatty acid ester; 15-20 parts of polyether modified oleic acid; 10-15 parts of modified amino silicon oil; the smoothing agent provided by the invention comprises the fatty acid ester, the polyether modified oleic acid and the modified amino silicon oil, the polyether modified oleic acid and the modified amino silicon oil are beneficial to improving the comprehensive performance of the smoothing agent, the smoothing agent is endowed with excellent smoothness, wettability and high temperature resistance, and when the smoothing agent is used in a polyester FDY oiling agent, the oil film strength is high, and the lubricating property is good. The antistatic property and the flame retardant property of the oiling agent can be improved, and the oiling agent is suitable for being specially used for the flame-retardant polyester fully-drawn yarn oiling agent.

The invention relates to the technical field of oil gas well tracing monitoring, in particular to a preparation method and application of an oil gas well tracing monitoring magnetic nano tracer agent. Comprising the following steps: dissolving FeCl3, FeSO4. 7H2O and doped metal salt in water, and introducing N2 to remove oxygen; the initial reaction temperature is 85 DEG C, rapidly adding ammonia water, reacting to generate Fe3O4 nanoparticles, doping elements, reducing the temperature to 60 DEG C, and firstly adding sodium citrate for primary carboxyl modification; adding a mixed solution of oleic acid and PEG twice; the pH value of the reaction system is controlled to be 9.5-10.5 in the whole process. The method has the beneficial effects that the doping amount is remarkably increased, the doping amount of doped elements is multiple times of that in the prior art, and the detection sensitivity is remarkably improved; in addition, oleic acid / PEG composite modification is adopted instead of single citric acid modification, so that the tracer is kept stably dispersed in high-salinity formation water; the superparamagnetism facilitates magnetic separation and recovery, and is suitable for harsh formation conditions.

The present invention relates to an artificially manipulated unsaturated fatty acid biosynthesis-associated factor and use thereof to increase the content of a specific unsaturated fatty acid of a plant body. More particularly, the present invention relates to a system capable of artificially controlling unsaturated fatty acid biosynthesis and a plant body produced thereby, which include an artificially manipulated unsaturated fatty acid biosynthesis-associated factor to control unsaturated fatty acid biosynthesis and a composition capable of artificially manipulating the factor. In a specific aspect, the present invention relates to artificially manipulated unsaturated fatty acid biosynthesis-associated factors such as FAD2, FAD3, FAD6, FAD7 and FAD8 and / or an unsaturated fatty acid biosynthesis controlling system by an expression product thereof.

The invention belongs to the technical field of mosquito larva prevention and control, and particularly relates to a mosquito-killing spreading oil agent and a preparation method and application thereof.The mosquito-killing spreading oil agent is composed of nerolidol, eugenol, methyl oleate, surfactants OP-4 and OP-10 and oleic acid, the mass percent of methyl oleate is 85%, the mass percent of a mixed preparation prepared from the surfactants OP-4 and OP-10 according to the mass ratio of 1: 1 is 5%, and the mass percent of oleic acid is 5%. The mosquito larva killing rate of the film spreading oil agent product within 60 minutes is 100%. Under the same condition, the effect of the insecticidal composition is better than that of pyrethrin, and the insecticidal speed is higher. The film spreading oil agent can reduce the chemical pesticide resistance of deet, and also can achieve the effects of environmental protection and efficient killing of mosquito larvae.

The utility model discloses a multistage extraction tower for preparing tall oleic acid, which comprises an extraction tower shell, a driving motor is arranged on the bottom surface of the extraction tower shell, a bearing is fixedly embedded on the inner bottom wall of the extraction tower shell, the inner ring of the bearing is fixedly connected with a rotating rod, and the output end of the driving motor is connected with the rotating rod through the bearing. A plurality of groups of stirring rods are fixedly connected to the outer surface of the rotating rod, a flow baffle is fixedly connected to the interior of the extraction tower shell, and a plurality of flow guide openings are formed in the upper surface of the flow baffle. According to the device, the flow baffle is matched with the flow guide opening to limit the flow of liquid, the electric push rod is matched with the flow adjusting plate, and the electric push plate drives the flow adjusting plate to linearly move, so that the flow adjusting plate blocks the flow guide opening to control the flow of the liquid, the extraction rate is controlled, and the extraction efficiency is controlled. The function is single, and the extraction rate cannot be controlled to control the extraction efficiency.

The invention discloses a preparation method of azelaic acid, which is characterized in that under a solvent-free condition, a reusable supported heteropolyacid salt catalyst is adopted to catalyze oleic acid to oxidize so as to prepare the azelaic acid. The method is characterized in that the supported heteropolyacid salt catalyst is supported phosphotungstate or supported silicotungstate, and the oxidizing agent is hydrogen peroxide. Compared with the prior art, the method has the advantages that the catalyst can be efficiently separated and reused, the production cost is reduced, the reaction process is simple, and the process is clean.

The invention provides a water-based rammed earth paint for an antique city wall. The water-based rammed earth paint comprises the following components: a main coating main material coating, a decorative layer transparent texture paint and a protective layer finish-coat paint, wherein the main material coating of the main coating comprises the following components: styrene-acrylic emulsion, modified color-selected snowflake white, coarse whiting, attapulgite, an auxiliary agent 1 and water; the decorative layer transparent texture paint comprises the following components: an acrylate copolymerized pure acrylic emulsion, a pigment, an auxiliary agent 2 and water; the protective layer finish-coat paint comprises the following components: acrylate polymerized pure acrylic emulsion, an auxiliary agent 3 and water; the modified color sorting snowflake white is obtained by reacting a modified silane coupling agent and color sorting snowflake white, and the modified silane coupling agent is obtained by modifying the silane coupling agent after copolymerizing oleic acid, hydroxypropyl acrylate and styrene. The color-selected snowflake white is modified, groups such as a long alkyl chain, polyacrylate, hydroxyl and a benzene ring are introduced, the compatibility with other components is enhanced, all the groups have a synergistic effect, and the comprehensive performance of the product is enhanced.

The invention discloses a composite material as well as a preparation method and application thereof, and relates to the technical field of high polymer materials. The composite material comprises the following components in parts by weight: 10-50 parts of epoxy resin; 10-20 parts of vegetable oleic acid; 1-3 parts of sulfur; 70-90 parts of a modified heat-conducting filler; the modified heat-conducting filler is obtained by modifying a heat-conducting filler through a double-bond-terminated silane coupling agent; the vegetable oleic acid comprises at least one of eleostearic acid, linolenic acid, linoleic acid, soybean oleic acid, oleic acid, ricinoleic acid and undecylenic acid. The composite material disclosed by the invention not only has the characteristics of high thermal conductivity and excellent electrical insulation performance, but also has good hot working performance and recycling capability, and shows a wide application prospect in the fields of high-thermal-conductivity green electronic packaging materials, electrical insulation coatings and sustainable composite materials.

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.

This invention discloses a novel siloxane defoamer synthesis and production process. The defoamer comprises 2-10 parts of hydrophobically treated fumed silica or nano-silica filler, 40-70 parts of a concentrated silicone oil composition, 40-70 parts of high-viscosity polydimethylsiloxane, and 100-150 parts of a fatty alcohol-propylene oxide polymer. Two types of concentrated silicone oil compositions are used, exhibiting diverse structures and chain lengths, totaling 16 types, with clearly defined preparation methods. The filler undergoes special hydrophobication treatment, and the preparation process includes mixing with the concentrated silicone oil, reaction heating, and centrifugal separation. The production process involves mixing the components in a specific ratio, followed by high-speed stirring, addition of oleic acid, and heating to obtain the novel siloxane defoamer. The components of this invention work synergistically to enhance defoaming and foam suppression capabilities. The process is simple, easy to operate and control, and the product has strong versatility. It performs excellently in high-viscosity oily systems, effectively solving foaming problems in various oily systems. It is low-cost, high-efficiency, and its performance is adjustable, exhibiting good stability and compatibility.

The present invention discloses a PVC / ABS / PC modified material and a preparation method thereof, belonging to the field of polymer material technology. The PVC / ABS / PC modified material comprises the following raw materials in parts by weight: 60-80 parts PVC, 30-40 parts ABS, 10-20 parts modified PC, 5-15 parts plasticizer, 2-5 parts stabilizer, 1-2 parts lubricant, and 1-2 parts antioxidant. The plasticizer is prepared by the following method: S1: bis(2-hydroxyethyl) terephthalate reacts with oleic acid chloride to form a double-chain unsaturated compound; S2: the double-chain unsaturated compound reacts with formic acid and H2O2 to form a diepoxide; S3: the diepoxide reacts with n-octanol to form the plasticizer. The PVC / ABS / PC modified material prepared by the present invention has good tensile properties and impact strength.

The invention discloses a medicine manufacturing technological process, relates to the technical field of pharmacy, and solves the technical problem that long-chain unsaturated fatty acid cannot be effectively removed in an existing technical scheme. The medicine manufacturing technological process comprises badger skin and comprises the steps that 1, badger skin fat is minced and mixed with water and sodium chloride to be heated, moisture is evaporated, and a mixture is obtained; a mixture containing badger fat and fat residues is obtained; 2, carrying out solid-liquid separation on the mixture obtained in the step 1 to obtain crude badger fat and fat residues; step 3, mixing the crude badger fat obtained in the step 2 with water, heating to boiling, then cooling, and obtaining an oleic acid intermediate by utilizing an oil-water separation technology; a pure physical method of low-temperature fractional crystallization and high-speed centrifugal separation is adopted to replace a traditional chemical alkali refining method, introduction of any chemical reagent in the production process is avoided, the risk of chemical residues is fundamentally eradicated, and the pure natural property and safety of a final product are guaranteed.

This invention discloses a method for preparing piperine starch microcapsules with sustained-release properties, belonging to the field of food processing technology. Using piperine as the core material, oleic acid as the oil phase carrier, and PG 2000 type octenyl succinate starch ester as the wall material, sustained-release piperine microcapsules are prepared through oil phase preparation, aqueous phase preparation, high-speed shearing, high-pressure homogenization, and spray drying. The microcapsules prepared by this invention have high encapsulation efficiency, small and uniformly distributed reconstituted particle size, and a stable system that is not prone to sedimentation. This allows for the slow and continuous release of piperine in simulated gastrointestinal fluid, significantly improving its poor water solubility, low stability, and low bioavailability. The resulting product can be widely used in the food, health product, and pharmaceutical fields.

The invention provides a high-temperature-resistant water shutoff agent as well as preparation and application thereof. The water shutoff agent is prepared from the following components in parts by weight: 100 to 110 parts of sodium lauryl alcohol phthalate, 45 to 55 parts of polyoxyethylene sorbitan monooleate, 60 to 70 parts of lignin surfactant, 65 to 75 parts of alpha-olefin sulfonate and 330 to 380 parts of oleic acid. The preparation process of the water shutoff agent comprises the following steps: adding the sodium lauryl alcohol ester phthalate and the polyoxyethylene sorbitan monooleate into a reaction kettle, and uniformly stirring to obtain a first reaction solution; adding a lignin surfactant and alpha-olefin sulfonate into the first reaction solution at one time, and uniformly stirring to obtain a third reaction solution; equally dividing oleic acid into two groups, adding one group of oleic acid into the third reaction solution, and uniformly stirring to obtain a fourth reaction solution; and adding another group of oleic acid into the fourth reaction liquid, uniformly stirring, and standing to obtain the water shutoff agent. The problems that a water plugging agent is poor in plugging effect in a high-temperature oil reservoir and low in crude oil recovery rate can be solved.

The invention belongs to the technical field of medical experimental animal models, and particularly relates to a construction method of a rabbit ear acne model for studying acne pathogenesis and drug curative effect. A healthy New Zealand large-ear white rabbit is selected, a testosterone solution is subcutaneously injected to induce endocrine disorder, oleic acid is smeared at an opening of an external auditory canal on the inner side of an ear, dermatobacterium acnes suspension is subcutaneously injected, and whether acne-like lesions such as erythema, papule and comedo appear on the skin of the ear or not is observed. The method is easy and convenient to operate, low in cost, good in repeatability, capable of simulating the pathological process of human acne and suitable for acne pathogenesis research and drug screening.