29 results about "Unsaturated fat" patented technology

The invention discloses a cationic lipid capable of being ionized and application of the cationic lipid. According to the ionizable cationic grease, adsorption is formed by the structural design of the head and biological drugs such as nucleic acid, and the encapsulation efficiency is improved; the tail part adopts a saturated or unsaturated aliphatic chain to form a branch structure, and the head part and the tail part are connected by an ester bond, so that in-vivo degradation is facilitated to reduce toxicity; due to the design of the unsaturated aliphatic chain, the membrane flowability during release of the endosome is improved, and the release efficiency of the biological medicine is effectively improved; moreover, the ionizable cationic grease provided by the invention has good temperature stability, not only can the product quality be improved, but also the accessibility of the product is expanded. In a word, the ionizable cationic lipid disclosed by the invention has the advantages of high encapsulation efficiency, low toxicity, high endosome release efficiency, good temperature stability and the like, the quality and the treatment effect of lipid nanoparticle drugs can be improved, and a new scheme and a new choice are provided for biological drug delivery.

The present application relates to the technical field of 5G high-frequency copper-clad plate, and particularly relates to polyimide, a preparation method thereof, a composition and a polyimide film. The polyimide is shown as formula 1, wherein n is an integer of 10-100; A is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups; R1 is selected from substituted or unsubstituted saturated aliphatic hydrocarbon groups; and R is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups. The present application adopts an anhydride containing a terminal carboxyl structure, seals the polyimide to form an oligomer prepolymer containing a carboxyl group, and then introduces a fatty alcohol containing a terminal hydroxyl group to form an ester group structure, so as to obtain a polyester polyimide. The material has a lower dielectric constant and higher adhesion. The polyimide is applied to thermoplastic polyimide (TPI), and the pressure bonding temperature is lower.

The roller end sealing device comprises a rubber fixing part, a sealing lip part and a framework part located between the rubber fixing part and the sealing lip part, and the inner end face of the sealing lip part is provided with a first sealing lip located on the medium side, a second sealing lip located on the air side and a third sealing lip located on the air side. Wherein the first sealing lip makes contact with the surface of the shaft body, non-contact gaps are formed between the second sealing lip and the shaft body and between the third sealing lip and the shaft body, and oleamide materials are doped in the first sealing lip and used for forming a lubricating grease film on the surface of a lip opening of the first sealing lip. According to the design scheme, the multiple sets of lip bodies making contact with or not making contact with the shaft body are integrated on the sealing lip part, oleamide is doped in the lip bodies making contact with the shaft body, an ultra-thin lubricating oil film can be formed in the using process, and the requirement for high-speed and grease lubrication can be met under the working conditions of high speed and grease lubrication; and meanwhile, the problems of lubrication, cooling, pollution prevention and leakage prevention of the sealing lip are solved.

An aqueous cosmetic composition for keratin fibers comprising: a) at least one acetylated or non-acetylated glucomannan polymer, b) at least one linear or branched, saturated or unsaturated C12-C22 fatty alcohol, c) at least one conditioning agent.

A long-chain composition has at least one long-chain alkane selected from the group consisting of C9-18 linear or branched alkanes and at least one long-chain carboxylic acid selected from the group consisting of C9-18 linear or branched, saturated or unsaturated aliphatic monocarboxylic acids. The mass ratio of the long-chain alkane to the long-chain carboxylic acid ranges from 1:1 to 40:1. The long-chain composition has a higher fermentation degree or higher substrate utilization rate and the like, when used as a starting material in the production of long-chain dibasic acids via fermentation.

The present application relates to the technical field of organic synthesis, and particularly provides a polyimide and a preparation method and a composition thereof.The polyimide of the present application is shown as formula 1, wherein n is an integer of 10-100; A is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups; R1 is selected from one or more of hydrogen, alkyl, cycloalkyl, aryl; and R is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups.The present application adopts an anhydride containing a terminal carboxyl structure, and terminates the polyimide to form an oligomer prepolymer containing a carboxyl group, and then introduces a polyphenyl ether containing a terminal hydroxyl group to form an ester group structure, so as to obtain a polyester imide.The material has a lower dielectric constant and higher adhesion, and the polyimide is applied to a thermoplastic polyimide (TPI), so that the pressure bonding temperature is lower.

The present application relates to a kind of fatty acid continuous separation system, utilize the different separation adsorption material to different saturation fatty acid adsorption ability different characteristics, realize the continuous separation of fatty acid on separation device, reach the accurate separation of different carbon chain length C12-C24 fatty acid, different double bond number fatty acid.The system can separate saturated fatty acid, unsaturated fatty acid and monounsaturated fatty acid, polyunsaturated fatty acid in fatty acid gradually, continuously;And saturated fatty acid separation rate is as high as 85% or more, unsaturated fatty acid separation rate is as high as 90% or more, wherein monounsaturated fatty acid separation rate is as high as 85% or more, polyunsaturated fatty acid separation rate is as high as 85% or more, with excellent market application prospect.

The application discloses an environment-friendly waterproof carton and a preparation method thereof, and relates to the technical field of waterproof cartons. The environment-friendly waterproof carton is prepared by coating a waterproof coating emulsion on the surface of a paperboard, solidifying, and folding; the waterproof coating emulsion comprises the following raw material components in a weight ratio: 30-40 parts of modified polyvinyl alcohol, 15-20 parts of modified starch, 6-10 parts of epoxy soybean oil, 0.2-0.4 parts of alkyl polyglycoside, and 40-50 parts of deionized water; wherein the modified polyvinyl alcohol is prepared by esterification modification grafting of polyvinyl alcohol with unsaturated fatty acyl chloride and saturated fatty acyl chloride, and then grafting with polycaprolactone-sulfhydryl through a sulfhydryl-alkene click reaction; and the modified starch is prepared by esterification modification grafting of starch with saturated fatty acyl chloride, and then carboxymethylation treatment.

The invention discloses a preparation method and a separation and purification method of all-cis and / or all-trans long-chain monounsaturated fatty acid and / or long-chain monounsaturated fatty alcohol. The structure of the all-cis and / or all-trans long-chain monounsaturated fatty acid and / or long-chain monounsaturated fatty alcohol is as shown in the following formula I. The invention further discloses a preparation method and a separation and purification method of the all-cis and / or all-trans long-chain monounsaturated fatty acid and / or long-chain monounsaturated fatty alcohol. The compound can be applied to preparation of lipid materials and ionizable lipid materials and further construction of drugs and gene delivery carriers.

Provided herein are polyesters that comprise (i) monomer units derived from sugar-based bicyclic diol; (ii) monomer units derived from an unsaturated aliphatic diacid; and (iii) monomer units derived from a saturated aliphatic diacid. The monomer units derived from the ethylenically unsaturated aliphatic diacid can be present in an amount of from greater than 0 mole % to 40 mole % of the polyester. These polyesters can be formed into articles using additive manufacturing methods. The resulting articles can be biocompatible, resorbable over a span of from 3 months to 12 months following implantation in the human body, and can exhibit desirable mechanical properties for applications, including porosity and elasticity.

The application discloses ionizable cationic lipids and application thereof. The ionizable cationic lipids of the application can form adsorption with biological drugs such as nucleic acids through structural design of a head part, so as to improve encapsulation efficiency; a saturated or unsaturated fatty chain is used to form a branched structure in a tail part, and an ester bond is used to connect the head part and the tail part, so as to facilitate in-vivo degradation and reduce toxicity; the design of the unsaturated fatty chain increases membrane fluidity during endosome release, so as to effectively improve the release efficiency of biological drugs; and the ionizable cationic lipids of the application have good temperature stability, which can not only improve product quality, but also expand product accessibility. In a word, the ionizable cationic lipids of the application have the advantages of high encapsulation efficiency, low toxicity, high endosome release efficiency and good temperature stability, can improve the quality and treatment effect of lipid nanoparticle drugs, and provide a new scheme and selection for biological drug delivery.

The invention provides a central nervous system delivery structure as well as a conjugate, a preparation method and application thereof. The delivery structure is represented by L-R, where L is a lipophilic group and R is a group comprising a structure for covalent attachment to a nucleic acid molecule; the lipophilic group is selected from a saturated or unsaturated hydrocarbyl group, a saturated or unsaturated fatty acid, and a saturated or unsaturated fatty alcohol; the structure covalently linked with the nucleic acid molecule comprises an-O-group in a hydroxyl group, and is covalently linked with a phosphorothioate group or a phosphate group of the nucleic acid molecule through the-O-group; r at least comprises an optionally substituted cycloalkyl group, an optionally substituted heterocyclic group, an optionally substituted heteroaryl group or an optionally substituted aryl group. The delivery structure is high in delivery efficiency, low in toxicity and simple in preparation method.

An acid-soluble nano material and a preparation method therefor and a use thereof, and a fracturing fluid, relating to petrochemical technology. The hydrodynamic particle size D10 of molecular aggregates of the acid-soluble nano material in water is 2-10 µm, D50 is 8-31µm, and D90 is 20-90µm. The preparation method for the acid-soluble nano material comprises: carrying out hydroxylation treatment on an unsaturated fatty monoacid, and carrying out a contact reaction between the hydroxylated unsaturated fatty monoacid and a nano carbonate raw material; and carrying out amination treatment on a product of the contact reaction, wherein the nano carbonate raw material contains a nano calcium carbonate raw material and / or a nano magnesium carbonate raw material. The acid-soluble nano material has the dissolution performance meeting fracturing construction requirements, can realize multi-size plugging in a compact reservoir and improve the plugging rate of a pore throat, and can enter the pore throat for adsorption and space occupation to reduce the retention amount of the fracturing fluid, thereby reducing damage to the reservoir.

The application discloses a low-temperature self-healing full-biological-based elastomer and belongs to the technical field of materials. The full-biological-based elastomer is synthesized by using a carboxyl-terminated low-molecular-weight biological-based unsaturated aliphatic prepolymer which is synthesized by polycondensation of nontoxic and renewable biological resources dihydric alcohol and diacid and then is crosslinked by an epoxy structure. The elastomer prepared by the application contains a physical crosslinking double dynamic network formed by beta hydroxy ester groups dynamic covalence and H bonds, which endows the full-biological-based elastomer with the functions of self-healing at low temperature and reprocessing of the material. The full-biological-based elastomer is prepared by using full-biological-based monomers, does not depend on fossil resources, and has simple preparation process, and can be used in multiple fields such as flexible wearable sensors and organic solar power generation.

The application discloses a kind of self-assembled nano-preparations based on hyaluronic acid-fatty acid coupling prodrug, the self-assembled nano-preparations use hyaluronic acid-fatty acid coupling prodrug as active ingredient, the hyaluronic acid-fatty acid coupling prodrug has structure shown in formula I, wherein, R is saturated or unsaturated fatty acyl;N=1~900, m=0~899.The application also discloses the preparation method of the above-mentioned self-assembled nano-preparations, and the application of the above-mentioned self-assembled nano-preparations in preparing anti-colitis drugs.The application avoids using pharmaceutical adjuvant, can avoid the allergic reaction and toxicity caused by adjuvant, has good biocompatibility and can be biodegraded, has good clinical conversion prospect.And it can realize intestinal inflammatory site and M1 macrophage target enrichment, eliminate excess ROS while inhibiting inflammatory response, has better anti-intestinal inflammation efficacy compared with clinical 5-amino salicylic acid, dexamethasone.

The invention discloses a frozen pig mouth peculiar smell reduction type synthetic flavoring agent as well as a preparation method and a marinating process thereof, and belongs to the technical field of synthetic flavoring agents. The composite flavoring agent comprises core-shell-crown synthetic flavoring agent particles, and the core-shell-crown synthetic flavoring agent particles comprise the following components in percentage by mass: a core layer: 30-42% of sodium glutamate, 1.5-2.5% of flavor nucleotides and 3-8% of yeast extract; a shell layer: 8.3 to 13 percent of synthetic phosphatidylcholine-TBHQ (tert-butyl hydroquinone) antioxidant lipidosome; and a canopy layer: 6-10% of methacrylic acid-2-hydroxyethyl ester / itaconic acid copolymerized microgel, and responds to release in a pH range of 4.5-5.0. The flavor enhancer in the frozen pig mouth peculiar smell reduction type synthetic flavoring agent can instantly permeate into collagenous fiber gaps under the condition of 0.06 MPa pulse pressure marinating and boiling, so that the peculiar smell generated due to the fact that high fat and high unsaturated fat are extremely easy to oxidize in a subsequent 4 DEG C cold chain is reduced.

This disclosure relates to compositions comprising preservatives for edible compositions and products thereof, and methods of making and using the same. Embodiments disclosed herein may include an edible composition comprising at least one unsaturated fat; and a preservative composition having a between 40% to 100% (w / w) total rice bran extract content, wherein the preservative composition is effective to: reduce at least an oxidation value of the edible composition such that the edible composition has at least 25% lower than the shelf life of a control not comprising the preservative composition, or increase shelf life of the edible composition that is at least 15% greater than the shelf life of a control not comprising the preservative composition.

The application discloses a kind of magnetic resonance human body fat composition determination method.Method for the signal amplitude of the proton of interest extracted in the magnetic resonance spectrum measured obtained to human body;The signal amplitude of the proton of interest is corrected, and then the relative concentration and relative concentration ratio of the proton of interest are obtained by processing;According to the relative concentration of the proton of interest, the fatty acid proportion is obtained by processing.The application can non-invasively measure human body fat composition, and can accurately quantify unsaturated fat protons using the data of edited spectrum, effectively avoid spectrum overlap, remove non-fat signals, realize spectrum signal correction, and finally realize accurate determination of fat composition.

The invention relates to a functionalized polyarylethersulfone copolymer (Pf) and to processes for preparing the functionalized copolymer (Pf). The functionalized copolymer (Pf) is derived from an unsaturated copolymer (Pu) which serves as polymeric scaffold containing C=C bonds which are permitted to react with a functionalization compound to form functional moieties in the copolymer (Pf). The copolymer (Pu) is made by polycondensation of an unsaturated aliphatic diol, another diol and a dihalodiarylsulfone. The present invention also relates to the use of the copolymer (Pf) in the preparation of an article, and to an article, such as membrane or chromatography material, comprising or made from the copolymer (Pf).

A silicone-free composition for conditioning hair comprises: a) at least one volatile alkane; b) at least one fatty substance selected from unsaturated fatty compounds comprising a C12-C20 carbon chain, fatty acid ester oils, and mixtures thereof; and c) at least one thickener selected from the group consisting of ester-terminated poly (ester-amide) polymers, copolymers of styrene and olefins, and mixtures thereof. A method for conditioning hair comprises applying the composition to the hair.

The invention discloses a self-assembled nano preparation based on a hyaluronic acid-fatty acid coupled prodrug, the self-assembled nano preparation uses the hyaluronic acid-fatty acid coupled prodrug as an active ingredient, the hyaluronic acid-fatty acid coupled prodrug has a structure as shown in a formula I, R is saturated or unsaturated fatty acyl; n is equal to 1-900, and m is equal to 0-899. The invention also discloses a preparation method of the self-assembled nano preparation, and an application of the self-assembled nano preparation in preparation of anti-colitis drugs. According to the invention, the use of pharmaceutical excipients is avoided, anaphylactic reaction and toxicity caused by the excipients can be avoided, the biocompatibility is good, the material can be biodegraded, and the material has a good clinical transformation prospect. And the dexamethasone can realize targeted enrichment at intestinal inflammation parts and in M1 macrophages, eliminates excessive ROS (reactive oxygen species) and inhibits inflammatory reaction at the same time, and compared with clinical 5-aminosalicylic acid, the dexamethasone has a better anti-enteritis curative effect.

A high stability formulation in the form of an aqueous mixture is disclosed. The formulation containing a quaternary ammonium organosilane hydrolysate includes the structure A(CH3)2N+(CH2)3Si(OZ)3-n(OH)n, wherein “A” is a saturated or unsaturated aliphatic chain having 12 to 18 carbons, “n” is an integer ranging from 0 to 2, “Z” is methyl or ethyl. A method to obtain the formulation includes a first reaction in which the tertiary amine group having the structure A(CH3)2N is quaternized by alkylation with a reactant having the structure (CH2)3Si(OR)3X, wherein X is halogen. Then, a second reaction is performed in which the tertiary amine remaining unreacted in the first reaction is quaternized with one or more supplementary reactants selected from benzyl chloride, benzyl bromide, benzyl iodide, vinyl benzyl chloride, vinyl benzyl bromide, vinyl benzyl iodide, epichlorohydrin, epibromohydrin, epiiodohydrin, chloroethanoic acid, bromoethanoic acid, iodoethanoic acid, and sultones, preferably 1,3-propane sultone or 1,4-butane sultone.

A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day.

The invention relates to a sulfur-crosslinkable rubber compound and a vehicle tire. The sulfur-crosslinkable rubber compound, containing - at least one diene rubber, - 10 to 500 phr silica, - at least one organosilicon compound of general formula I - where R is the same or different and H is a cyclic, straight-chain or branched C1 to C 12 , preferably C1 to C8, particularly preferably C1, -alkyl group, a carboxyl group (-COOH), a substituted or unsubstituted aryl group, preferably a phenyl group, or a substituted or unsubstituted aralkyl group, R' the same or different and a branched or unbranched, saturated or unsaturated, aliphatic, aromatic or mixed aliphatic / aromatic divalent C1-C 30 , preferably C1-C 20 , especially preferred C2-C 20 , especially preferred C3-C15 -hydrocarbon group is x is an average chain length of 1 to 10, - 0.5 - 5 phr zinc stearate and - less than 0.5 phr of a vulcanization accelerator selected from the group of guanidines and aldehydes.

The present disclosure provides a fryer containing a microbially derived oil; comprising a content of monounsaturated fat of at least 90% wt., a polyunsaturated fat of up to 3%, or both, where the fryer consumes less power to cook a food type, as compared to a fryer comprising a plant derived oil used to cook an identical food type, the oil having less aldehydes, alkenals, or alkadenials after cooking as compared to a plant derived oil, in which the oil or fried food comprises a reduced content of total polar materials as compared to a same food cooked in a plant derived oil at a same temperature for a same time, optionally, in which the oil prevents or reduces adhesion of a first particle of the food to a second particle of the food when cooked in the microbially derived oil.

Provided herein is an oil composition for conditioning hair, comprising: a) at least one unsaturated fatty alcohol comprising a C12-C20 carbon chain; b) at least one volatile alkane; and c) at least one fatty acid ester oil, wherein the composition does not comprise silicone. Provided herein is a method for conditioning hair comprising applying to the hair a composition as described above.

The present application relates to the technical field of polyimide, and specifically provides a polymer, a preparation method thereof, a composition and a polyimide film.The polymer is shown as formula 1, wherein n is an integer of 10-100; A is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups; R1 and R2 are independently selected from one or more of hydrogen, alkyl, cycloalkyl and aryl; and R is selected from one or more of substituted or unsubstituted aromatic hydrocarbon groups, saturated or unsaturated aliphatic groups.The present application adopts an anhydride containing a terminal carboxyl structure, seals the polyimide to form an oligomer prepolymer containing a carboxyl group, and then introduces an aromatic alcohol containing a terminal hydroxyl group to form an ester group structure, so as to obtain a polyester imide.The material has a lower dielectric constant and higher adhesion, and the polyimide is applied to thermoplastic polyimide (TPI), so that the pressure bonding temperature is lower.