5682 results about "Dimethyl sulfoxide" patented technology

An immunogenic composition having 13 distinct polysaccharide-protein conjugates and optionally, an aluminum-based adjuvant, is described. Each conjugate contains a capsular polysaccharide prepared from a different serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F) conjugated to a carrier protein. The immunogenic composition, formulated as a vaccine, increases coverage against pneumococcal disease in infants and young children globally, and provides coverage for serotypes 6A and 19A that is not dependent on the limitations of serogroup cross-protection. Methods for making an immunogenic conjugate comprising Streptococcus pneumoniae serotype 19A polysaccharide are also provided in which the serotype 19A polysaccharide is co-lyophilized with a carrier protein and conjugation is carried out in dimethyl sulfoxide (DMSO) via a reductive amination mechanism.

Described are oral sensory perception-affecting compositions containing dimethyl sulfoxide, complexes thereof and salts thereof, specifically:(i) dimethyl sulfoxide; and(ii) a second compound or group of compounds:(a) containing at least one menthyl moiety; and/or(b) containing at least one vanillyl moiety; and/or(c) containing at least one carboxamide moietywhen the weight ratio of "second compound(s)":dimethyl sulfoxide, is in the range of from about 1,000:1 down to about 3:10 and food grade acceptable salts thereof. Also described are oral sensory perception-affecting (e.g., "coolant")-imparting consumable articles (e.g., mouthwashes and the like) comprising a consumable article base and at least one of the aforementioned oral sensory perception-affecting compositions. Also described are complexes of (i) dimethyl sulfoxide and (ii) at least one of the aforementioned second compounds or group(s) of compounds.

A method of removing photoresist and/or resist residue from a substrate includes exposing the substrate to a supercritical fluid in combination with a co-solvent mixture comprising an organic solvent and an oxidizer. In one embodiment, the supercritical fluid is supercritical carbon dioxide and the co-solvent mixture includes 1,2-Butylene Carbonate, Dimethyl Sulfoxide and hydrogen peroxide. If desired, supercritical carbon dioxide in combination with a second co-solvent mixture may be subsequently applied to the substrate to rinse and dry the substrate. In one embodiment, the second co-solvent mixture includes isopropyl alcohol.

The invention discloses a method for preparing polyacrylonitrile carbon fiber protofilament by dry and wet methods. The method comprises the steps of polymerization, demonomerization and defoaming, filtration, coagulation, washing and drafting, oiling densification, steam drafting, heat setting and drying. Three-level coagulating baths at the temperature of between 10 DEG C below zero and 70 DEG C and with dimethyl sulfoxide with concentration of 10 to 60 mass percent are adopted in the coagulation step, and the first coagulating bath contains aqueous ammonia accounting for 0.05 to 1 percent of the mass of the first coagulating bath; and a spinning head is subjected to 1.5 to 5 times positive drafting in the first coagulating bath, and the drafting is 0 in the second and third coagulatingbathes. According to the method for preparing the polyacrylonitrile carbon fiber protofilament, the spinning process is stable, the broken filament is little, the spinning speed is high, the spinningis stable, the prepared protofilament has few defects, the density is not less than 1.180g/cm<3>, and the tensile strength is not less than 7cN/dtex. The protofilament can be prepared into a high-performance carbon fiber with tensile strength of more than 4.9GPa and elastic modulus of between 260 and 280GPa by high-temperature carbonization.

The invention provides a cell freezing medium which can be clinically safely used and is used for freezing human cells. The cell freezing medium comprises: 2-8wt% of human albumin, 5-10 volume% of dimethyl sulfoxide, 3.5-5.1wt% of dextranum-40 and 2.75-4.25wt% of glucose.

The invention relates to a polyvinyl alcohol-polypeptide-polyethylene glycol graft copolymer and a preparation method thereof. The molecular weight of polyvinyl alcohol is 20,000-80,000; the molecular weight of a polypeptide chain segment is 4,000-8,000; and the molecular weight of a polyethylene glycol chain segment is 350-750. The preparation method comprises the following steps of: (1) synthesizing a polypeptide homopolymer which contains an end-NCO radical: adding the polypeptide homopolymer, diisocyanate, dibutyltin dilaurate serving as a catalyst and dimethyl sulfoxide serving as a solvent into a reactor for reacting to obtain a target product; (2) synthesizing a polyvinyl alcohol-polypeptide graft copolymer: adding the polypeptide homopolymer which contains the end-NCO radical, the solvent and the catalyst into the reactor, adding polyvinyl alcohol and reacting to obtain a target product; and (3) synthesizing a polyvinyl alcohol-polypeptide-polyethylene glycol graft copolymer: adding the polyvinyl alcohol-polypeptide graft copolymer, the solvent and the catalyst into a drying reactor, adding polyethylene glycol monomethyl ether and reacting to obtain a target product.

The invention relates to a Chinese medicine for treating psoriasis, in particular to Chinese medicinal powder for treating psoriasis. The Chinese medicinal powder for treating psoriasis consists of Chinese medicinal powder for oral administration and external embrocation, wherein the Chinese medicinal powder for oral administration consists of 45 Chinese medicines of angelica dahurica, cicada slough and the like; and the external embrocation consists of 18 Chinese medicines of centipede, scorpion and the like and medicinal ethanol and dimethyl sulfoxide. In the Chinese medicinal powder for treating psoriasis, on the basis of a secret recipe handed down in the family, the pathogenesis of psoriasis is found, and Chinese medicinal decoction tablets which are beneficial for clearing heat, cooling blood and detoxicating, dispelling wind, arresting itching and detoxicating, removing dampness, promoting blood circulation and detoxicating, enriching blood, moistening dryness and detoxicating or Chinese medicinal decoction tablets of insects medicines for detoxicating and eliminating toxic materials and the like are subjected to compatibility scientifically by many years of clinical experiences, and medicines for oral administration and external use are prepared by the conventional process; and due to the adoption of the conventional preparation technology, the Chinese medicinal powder for treating psoriasis is a pure Chinese medicinal preparation, has the characteristics of addressing both symptoms and root causes along with no toxic or side effect, relapse prevention and the like, is convenient to use, economic and practical, and patients can use safely and have light burden.

The invention discloses a preparation method for a graphene/aramid fibre 1414 nano-fibre composite membrane, comprising the following steps of: performing nano-fibrillation on aramid fibre 1414 yarns via the solution system of dimethyl sulfoxide and potassium hydroxide; slowly adding dimethyl sulfoxide solution for oxidizing graphene, sequentially centrifuging, dispersing, performing suction filtration and film formation, and thus obtaining oxidized graphene/aramid fibre 1414 nano-fibre composite membrane; and reducing via hydroiodic acid, washing, drying, and thus obtaining the graphene/aramid fibre 1414 nano-fibre composite membrane. The tensile strength and the Young modulus of the graphene/aramid fibre 1414 nano-fibre composite membrane obtained by the preparation method disclosed by the invention can achieve 209.4 Mpa and 29.5 GPa respectively, thus showing excellent mechanical property; simultaneously, the conductivity of the graphene/aramid fibre 1414 nano-fibre composite membrane can achieve 175 S/m, thus being excellent in conductance; and a thermogravimetric analysis shows that the graphene/aramid fibre 1414 nano-fibre composite membrane is good in heat stability.

The present invention initiates the copolymerization reaction of acrylonitrile and a comonomer with azo-bis-iso-heptonitrile in the dimethyl sulphoxide solution, and can adjust the molecular weight of an acrylonitrile copolymer with a bit of acrylonitrile, under the condition of 30 to 45 DEG C, the acrylonitrile copolymer having high molecular weight and narrow molecular weight. The present invention is characterized in that by adopting a traditional free radical polymerization method, the azo-bis-iso-heptonitrile is initiating agent, the molecular weight of a copolymer is adjusted with propenol, the synthetic molecular weight can be adjusted and controlled in 100 thousands to 900 thousands, the molecular weight distributes an acrylonitrile copolymer with an index smaller than 2.3, and the acrylonitrile copolymer solution can be used for preparing the spinning liquid of high performance carbon fiber.

The invention provides a cell freezing medium. The cell freezing medium comprises acylated epsilon polylysine, polyhydric alcohols and equilibration buffer. According to the cell freezing medium disclosed by the invention, the polyhydric alcohols and acylated epsilon polylysine replace toxic dimethyl sulfoxide so as to serve as cryoprotective agents, so that damage to cells in the freezing resuscitation process is reduced, and the cell survival rate is improved. The invention further provides a method for performing freezing resuscitation on cells by utilizing the cell freezing medium and application of the method for freezing stem cells and immune cells. The method is simple and feasible to operate and is suitable for large-scale clinical application of cell therapy, and great convenienceis brought to clinical application of the cell freezing technology.

The invention relates to a silver-modified carbon nitride composite photocatalytic material and a preparation method thereof. The preparation method comprises: dissolving dicyanodiamide or melamine in deionized water or dimethyl sulfoxide and performing ultrasonic dispersing, so as to obtain a dicyanodiamide or melamine dispersion liquid; dissolving silver nitrate in deionized water and stirring uniformly, so as to obtain a silver nitrate solution; slowly dropwise adding the silver nitrate solution into the above dicyanodiamide or melamine dispersion liquid under the condition of magnetic stirring, and continuing stirring the solution, so as to obtain a mixed precursor solution; using anhydrous ethanol and deionized water repeatedly wash the obtained mixed precursor solution for multiple times, and performing vacuum drying; and putting the obtained product in a proper crucible and covering, putting in a high-temperature furnace, and sintering for a period under the condition of nitrogen protection, so as to obtain a powdery sample. The advantages comprise that the raw material source is wide, the preparation technology is simple and practicable, and the cost is relatively low; and the prepared composite photocatalytic material has relatively good photocatalytic degradation effect on organic dye rhodamine B under irradiation of visible light.

A process for preparing hydrofluoroether features the reaction between one of trifluoroethene, tetrafluoroethene, hexafluoro propene, etc and one of trifluoroethanol, trifluoropropanol, metanol, etc in organic solvent (DMF or DMSO). Its advantages are high output rate and easy purifying and separating.

The present invention discloses one kind of seed coating agent for raising cold resistance of super sweet corn seed. The seed coating agent is mixture of cold resisting components including dimethyl sulfoxide 0.5-5 wt% and praline 0.005-1 wt%; nutritious components including glucose 0.1-2 wt%, vitamin C 0.01-0.5 wt%, amino acid 0.5-7 wt%, zinc sulfate 0.05-0.5 wt% and potassium dihydrogen phosphate 0.05-0.9 wt%; plant growth regulator including gibberellin 0.004-0.025 wt% and naphthylacetic acid 0.01-0.35 wt%; one or two pesticides 0.3-8 wt%; germicide 5-15 wt%; filming including agent chitosan 0.15-2 wt% and gum Arabic 1-8 wt%; penetrant alcohol 2-10 wt%; red pigment as warning color 0.5-1.5 wt% and water for the rest. The present invention can raise the cold resistance of super sweet corn seed, prevent and control diseases and pests, regulate the growth of super sweet corn seed and increase yield.

The invention provides a method for preparing an iodic liquid embolic agent capable of long-time self-developing. Water-soluble polyvinyl alcohol (PVA) is added with pyridine to be stirred and evaporated for removing the pyridine. Residual reactant is dehumidified and dissolved in dimethyl sulphoxide (DMSO) organic solvent and then is added with solution of iodic compound and dichloromethane and added with triethylamine; and an obtained iodic product (I-PVA) is poured into a mixture of butyl ether and acetone to be deposited and separated. The iodic product is washed in water, is dried and then is confected into the liquid embolic agent by the dimethyl sulphoxide or N-methyl-ketopyrrolidine organic solvent. The liquid embolic agent prepared by the invention is injectable and can develop under X-ray for a long time. When contacting with blood, the organic solvent diffuses fast for depositing and separating solid to take embolic effect. The embolic agent can be used for embolotherapy of cerebral arteriovenous malformation, tumour and other vascular disease.

A process for producing lyophilized competent cells wherein competent cells are that can be stored or shipped as freeze-dried cells at temperatures between 0° C. and 8° C. and remain suitable for cloning genes or DNA fragments. The process includes culturing cells, rending the cells competent, and lyophilizing the cells. Once lyophilized, the cells can be stored or shipped as freeze-dried cells. The lyophilized cells are prepared for transformation protocols by being re-hydrated in a solution of dimethyl sulfoxide. Once re-hydrated, the transformation efficiency of the competent cells is at least 5x105 transformations per microgram of DNA.

The present invention relates to a method for preparing polyvinylidene fluoride membrane with modified hydrophilicity. Said method includes the following steps: (1), membrane-casting liquor preparation: using (by wt%) 10-18% of polyvinylidene fluoride, 2-10% of polyvinyl alcohol and 80% of dimethyl sulfoxide, mixing them to obtain their mixed liquor, placing said mixed liquor in a water bath with 98deg.C, stirring for 6h, then standing still and defoaming so as to obtain uniform membrane-casting liquor; and (2), membrane preparation: under the condition of room temperature utilizing said membrane-casting liquor to prepare plate membrane or utilizing wet process to spin hollow fiber membrane, then promptly soaking the plate membrane or hollow fiber membrane into a coagulation bath, retaining for 24h, then solidifying and forming, washing the formed membrane by using clean water, and soaking the formed membrane in a glycerine aqueous solution whose mass concentration is 60% for 12h, taking out said formed membrane and naturally drying in air so as to obtain the invented polyvinglidene fluoride plate membrane or hollow fiber membrane with good hydrophilicity. The above-mentioned coagulation bath is one kind of water, ethyl alcohol aqueous solution whose mass concentration is 20% or sodium chloride aqueous solution.

A cryopreservation solution of tissue engineering products uses DMEM culture solution as a basic solvent which is added with vitamin B, vitamin C, chondroitin sulfate, beta-integrin, cromolyn sodium, cytochalasin B, L-glutamine, bovine serum albumin, fetal bovine serum, trehalose, sodium carbonate, polysucrose-70, and dimethyl sulfoxide added during freezing storage. The cryopreservation solution provided by the invention has little toxicity to cells and long storage time, and can be stored for six months under 80 DEG C below zero, and 12 to 18 months in liquid nitrogen; and the cell viability of the resuscitated cells can be over 60%. The stored tissues can be simply and conveniently used after being resuscitated for only three to five min in water bath under the temperature of 37 DEG C and being washed by sterilized saline water. The invention can be widely used, and is suitable for tissue engineering skin, tissue engineering cornea, tissue engineering blood vessel, tissue engineering nerve and the like, and also is applicable to the cryopreservation of normal tissues.

The invention provides a preparation method of dimethyl sulfoxide, the method is as follows: in oxidation reaction conditions, dimethyl sulfide is contacted with at least one oxidant, and the catalyst contains at least one titanium silicon molecular sieve. According to the preparation method of the dimethyl sulfoxide, the dimethyl sulfide conversion rate is high, the effective utilization rate of the oxidant is high, the dimethyl sulfoxide selectivity is good, the usage amount of the dimethyl sulfide and the oxidant can be effectively reduced, and the production cost of the dimethyl sulfoxide can be reduced. According to the method of the invention, the activity stability of the catalyst is good, even by long-time continuous operation and multiple-times of cycle use of the catalyst, a high dimethyl sulfide conversion rate, a high effective utilization rate of the oxidant and high dimethyl sulfoxide selectivity also can be achieved. In addition, the method of the invention is mild in reaction condition, easy to control, and suitable for mass production.