3560 results about "Polycaprolactone" patented technology

The present invention is directed to microparticles, to microparticle compositions containing the same, to methods of forming the same, and to uses for the same, including use for a vaccine, for raising an immune response, for treatment of a disease and for diagnosis of a disease. The microparticles comprise a biodegradable polymer, such as a poly(α-hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, or a polycyanoacrylate, and a detergent selected from a cationic detergent and an anionic detergent. The microparticles further comprise an antigen adsorbed on the surface of the microparticle.

A fully curable jettable composition having a viscosity less than 30 cps at a temperature within the range of 15-180° C., more preferably at a temperature of 15-100° C., e.g. 60-80° C. the composition comprising: (A) at least one low viscosity reactive resin selected from the group consisting of compounds containing an oxetane ring, cycloaliphatic epoxy resins, tetrahydrofurans, hexahydropyrans and mono-functional (meth)acrylates, said resin having a molecular weight of not greater than 300 Daltons, e.g. 250 Daltons or less, and a viscosity at a temperature in the said range of less than 30 cps, e.g. 5 to 15 cps; (B) at least one higher viscosity resin selected from the group consisting of epoxy resins, compounds containing an oxetane ring and acrylates, which resin acts to thicken the low viscosity resin and strengthen a jetted deposit of the composition, the higher viscosity resin having: a viscosity greater than twice that of the low viscosity resin at the said temperature in the range stated above, and a functionality of greater than or equal to 2; (C) at least one curable toughener, preferably having a functionality of at least 2, such as hydroxy, epoxy, acrylic or other reactive functionalised polymer/oligomer (e.g. derived by functionalising poly(tetrahydrofuran), polycaprolactone, polycarbonate diol, or a dendrimeric polyol; (D) at least one initiator for the polymerisation of the resins, and (E) at least one stabiliser for delaying the curing of the resins of the composition; wherein the low viscosity resin is slower to react than the higher viscosity resin and acts to solvate the higher viscosity resin prior to curing and at least partly during curing and wherein at least 30% of the components A and B are cationically curable resins. The composition can be jetted from piezo electric printing heads under the control of a computer program to form a multi-layered article, e.g. a three dimensional article, in which the adjacent droplets merge and are cured homogeneously together.

The invention discloses a composite fibre membrane with an unidirectional water permeable performance and a preparation method of the composite fibre membrane, belonging to the field of functional micron/nano composite fibre materials; the composite fibre membrane is composed of a two-layer structure; a hydrophile layer is a nano-scale fibre membrane composed of hydrophile polymers such as polyvinyl alcohol, cellulose acetate, polyacrylate and the like; fibre diameter is 100-800nm; thickness is 25-35 microns; a lyophobic layer is the micron-scale fibre membrane composed of lyophobic polymers such as polyurethane, polystyrene, polymethylmethacrylate or polycaprolactone and the like; thickness is 5-10 microns; and fibre diameter is1.0-3.0 microns. The composite fibre membrane can be controlled by regulating technical parameters and has hydrophile/lyophobic differences and an excellent directional water permeable performance; and the preparation method is characterized by simple operation, low energy consumption, high efficiency and is widely used for fields of perspiring-type waterproof dress materials, fuel cell electrolyte membranes, unidirectional liquid transmission and separation and the like.

Provided herein is a composite, comprising: a polymer host selected from the group consisting of low-density polyethylene (LDPE), linear low-density polyethylene (LLDPE), polyethylene terephthalate (PET), polytetrafluoroethylene (PTFE), and polypropylene (PP), polyurethane, polycaprolactone (PCL), polydimethylsiloxane (PDMS), polymethylmethacrylate (PMMA), and polyoxymethylene (POM); and a guest molecule comprising hyaluronic acid; wherein the guest molecule is disposed within the polymer host, and wherein the guest molecule is covalently bonded to at least one other guest molecule. Also provided herein are methods for forming the composite, and blood-contracting devices made from the composite, such as heart valves and vascular grafts.

The present invention provides a card base which is degradable by microbes in natural environment. The card base is excellent in properties necessary for card bases, such as tensile strength, impact strength, flex temperature, heat resistance, resistance to thermal expansion and contraction, blocking resistance and humidity resistance, and has rigidity, bending resistance and durability. The card base contains, as essential components, a 3-hydroxybutylate/3-hydroxyvalerate copolymer and a lactic acid polymer, and, where necessary, a polycaprolactone or a high-molecular aliphatic polyester. The card base has a single-layer structure, or a sandwich structure further having overlay layers comprising a composition containing, as essential components, a lactic acid polymer and either or both of a polycaprolactone and a high-molecular alphatic polyester.

Water-repellant, self-cleaning coatings and methods of making and using thereof are described herein. In one embodiment, a hydrophobic or super hydrophobic coating is applied to the surface of a golf ball to make the golf-ball water-repellant and self-cleaning. Suitable coating materials include silicone compounds, silicone compounds, nanoparticles, silanes, fluorocarbon polymers, perfluoroalkyl ethyl methacrylate (PPFEMA) coated polycaprolactone, hydrocarbons, polymer mats made of polystyrene and poly[tetrafluoroethylene-co-(vinylidene fluoride)-co-propylene] (PTVFP); polyethylene glycol with glucose and sucrose in conjunction with a hydrophobic substance; combinations of nanoparticles with polyethylene or polypropylene; high density polyethylene, technical waxes; films of rough particles of metal oxides, polymer binder layers containing a plurality of porous protrusions, and combinations thereof. Suitable coating techniques include, but are not limited to, spraying, dipping, painting, brushing, or wiping (such as applying the coating from a towel or sponge). The coating material or the outer layer of the golf ball may be modified to create nano- or micro roughness or patterns on the surface of the golf ball, which can induce the lotus effect. This roughness or pattern can be created using a variety of techniques known in the art including, but not limited to, etching, top/down methodologies, bottom/up methodologies, or combinations thereof.

A photoimagable composition suitable for use as a negative photoresist comprising: (A) at least one epoxidized polyfunctional bisphenol A formaldehyde novolak resin; (B) at least one polycaprolactone polyol reactive diluent, wherein the amount of component (A) is from about 95% to about 75% by weight of the sum of (A) and (B) and the amount of component (B) is from about 5% to about 25% by weight of the sum of (A) and (B); (C) at least one photoacid generator in an amount from about 2.5 to about 12.5 parts per hundred parts of resin and reactive diluent, which initiates polymerization upon exposure to actinic radiation; and (D) a sufficient amount of solvent to dissolve (A), (B) and (C); wherein the solvent comprises 2-pentanone, 3-pentanone, and 1,3-dioxolane and mixtures thereof.

A new embolic agent, bioabsorbable polymeric material (BPM) is incorporated to a Guglielmi detachable coil (GDC) to improve long-term anatomic results in the endovascular treatment of intracranial aneurysms. The embolic agent, comprised at least in part of at least one biocompatible and bioabsorbable polymer and growth factors, is carried by hybrid bioactive coils and is used to accelerate histopathologic transformation of unorganized clot into fibrous connective tissue in experimental aneurysms. An endovascular cellular manipulation and inflammatory response are elicited from implantation in a vascular compartment or any intraluminal location. Thrombogenicity of the biocompatible and bioabsorbable polymer is controlled by the composition of the polymer. The coil further is comprised at least in part of a growth factor or more particularly a vascular endothelial growth factor, a basic fibroblast growth factor or other growth factors. The biocompatible and bioabsorbable polymer is in the illustrated embodiment at least one polymer selected from the group consisting of polyglycolic acid, poly~glycolic acid/poly-L-lactic acid copolymers, polycaprolactive, polyhydroxybutyrate/hydroxyvalerate copolymers, poly-L-lactide. Polydioxanone, polycarbonates, and polyanhydrides.

The invention discloses an efficiency oil and water separation composition fiber film and a preparation method thereof, and belongs to the field of functional nanometer fiber materials. Hydrophobic polymers such as polyurethane, polystyrene and polymethyl methacrylate or polycaprolactone are used as the main raw materials of the fiber film, the main raw materials are dissolved in an organic solvent to form a polymer solution, hydrophobic nanometer particles are added into the polymer solution in the preparation process, after the mixture is evenly mixed, electro-spinning is conducted on the mixed solution by means of the electrostatic spinning method, and then a fiber film material which is formed by micro-nanometer composite structures and is in the shape of non-woven fabric is obtained. The electro-spun fiber film of the micro-nanometer structure has super-hydrophobic/super-oleophylic property in the air and excellent oil adsorption performance, and the contact angle to oil is nearly zero. The efficient oil and water separation composite fiber film is simple in preparation method, low in energy consumption, high in efficiency, high in oil and water separation speed, and capable of being widely used in the fields such as oily water efficient purification.

There is provided a method to modify biodegradable polymers using the direct reaction of a biodegradable polymer in a vinyl monomer and may take place in the presence of initiators. The initiator may be free radical initiators, heat, ionic initiators, UV irradiation, ionizing irradiation and other high energy irradiation. Suitable biodegradable polymer include polycaprolactone, poly(lactic acid), poly(glycolic acid) and poly(lactic-co-glycolic acid). Suitable vinyl monomers include acrylates, methacrylates and the like.

A protective and/or splint device, for example a distal radial splint device (200), comprises a protective and/or splint member (201) and a spacer member (13). The protective and/or splint member (201) comprises a composite protective and/or splint material and is formable at a forming temperature and is substantially rigid at ambient temperature. The material comprises a polycaprolactone and a ligno-cellulose additive material. The protective and/or splint member (201) comprises a mesh of elements (202), with a plurality of openings (203) through the protective and/or splint member (201). Away from the periphery of the splint member (201), the openings (203) are diamond-shaped. Two border elements (204) extend along the two sides of the periphery of the splint member (201). The three point bending strength to openness ratio of the member is greater than 0.1 and the unidirectional bending strength to openness ratio of the member is greater than 4. This results in a device (200) with sufficient strength, which is breathable with open surfaces, and the volume of material used is optimized. The strength of the member (201) parallel to the longitudinal direction of the arm is greater than the strength parallel too the circumferential direction. At the forming temperature the member (201) is stretchable. The member (201) is rounded between the outer surface of the member (201) and the edges around the openings (203).

A cage for facilitating fusion of bones, such as vertebrae, or fusion of adjacent bone surfaces is disclosed. In one form, the cage includes a plurality of spaced apart walls comprising a biodegradable polymeric material (e.g., polycaprolactone); an osteoconductive mineral coating (e.g., a calcium compound) on at least a portion of the walls; and a bioactive agent (e.g., a bone morphogenetic protein) associated with the polymeric material and/or the coating. The bioactive agent is present in amount that induces ossification between the bones or adjacent bone surfaces. The cage may also include a fixation plate connected to at least one of the walls.

A mouth guard composed of a polymer consisting essentially of polycaprolactone exhibits a low softening point, enabling it to be easily custom-fitted by the user or a health professional. The material is provided in the form of a generally U-shaped, unformed sheet of material, enabling the material to be heated with hot water or microwave energy and custom-fitted to the dentition of a user. The mouth guard may be perforated and may include a no-stick layer and/or a flavoring agent. A plurality of mouth guards may be provided in different sizes for children and adults and different shapes for different sports. In the preferred embodiments the mouth guard has a periphery including a plurality of lobes and cusps to enhance fitting. A method of fabricating an improved mouth guard according to the invention is also disclosed.

The present invention refers to a polymeric composition prepared from a biodegradable polymer defined by poly-hydroxybutyrate (PHB) or copolymers thereof, and at least one other biodegradable polymer, such as polycaprolactone (PCL) and poly (lactic acid) (PLA), so as to alter its structure, and further at least one additive of the type of natural filler and natural fibers, and, optionally, nucleant, thermal stabilizer, processing aid, with the object of preparing an environmentally degradable material. According to the production process described herein, the composition resulting from the mixture of the modified biodegradable polymer and additives can be utilized in the manufacture of injected packages for food products, injected packages for cosmetics, tubes, technical pieces and several injected products.

The invention discloses a method for improving water resisting performance of a polyvinyl alcohol film from polycaprolactone and polylactic acid. The method comprises the following steps: (1) synthesis of polycaprolactone containing terminal-NCO groups: adding polycaprolactone, diisocyanate, a catalyst and a solvent in a drying reactor, and stirring for reaction at the temperature of 50-55 DEG C so as to obtain a target product; (2) synthesis of polyvinyl alcohol-polycaprolactone graft copolymer: adding the polycaprolactone containing terminal-NCO groups, polyvinyl alcohol, a solvent and a catalyst in the drying reactor, stirring for reaction at the temperature of 50-55 DEG C so as to obtain a target product; and (3) preparation of a polyvinyl alcohol film modified by polycaprolactone and polylactic acid: adding the polyvinyl alcohol-polycaprolactone graft copolymer, polylactic acid and a solvent in the drying reactor, and stirring for mixing at the temperature of 40-50 DEG C, forming a film via a tape casting process and drying the film so as to obtain a target product. The preparation technology is simple and easy to master, and the water resisting performance of the modified membrane is improved greatly.

A multi-layer screen protector for digital display screens, such as LCD's, cell phones, tablets, laptops, and pad computer devices, that may be readily applied without the need for special tools and in dusty environments, the screen protector being designed and die-cut to match the shape of the digital display screen, including cut-outs for cameras, microphones and device buttons, where the top surface is a layer of polycaprolactone aliphatic urethane that is connected to a bottom layer made from plastic such as polystyrene, acrylic and/or polyethylene terephthalate, and a self-wetting adhesive layer provided on the bottom surface of the bottom polystyrene, acrylic and/or polyethylene terephthalate layer. The screen protector provides an optically clear view of the device and is constructed with the abrasion resistant layer being provided and supported on a plastic layer and may be removed and reinstalled.

The invention discloses an all-solid-state composite polymer electrolyte and a preparation method thereof. An adopted polymer matrix is a hyperbranched polymer or a star-like polymer. Different types of lithium salt are added into the polymers, and are compounded with substances such as inorganic fillers (such as nanoparticles, nanofibers), ionic liquid, carbonic ester compounds as well as other linear or branched polymers (such as polyether, polydioxolane, polycaprolactone, polyphosphazene, polyurethane, Makrolon, polyamide, polyimide, polyester, polyvinylidene fluoride, polytetrafluoroethylene, polyhexafluoropropylene or corresponding segmented copolymers or graft polymers thereof and the like) respectively, a film can be formed through a solution pouring process, the all-solid-state composite polymer electrolyte is prepared, and the room-temperature conductivity of the electrolyte is approximate to 10<-4> S/cm. The solid electrolyte has potential applications in electrochemical devices such as secondary lithium ion batteries, supercapacitors, electronic sensors, electrochromic devices and the like.