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22 results about "Hard tissue" patented technology

Hard tissue (also termed calcified tissue) is tissue which is mineralized and has a firm intercellular matrix. The hard tissues of humans are bone, tooth enamel, dentin, and cementum. The term is in contrast to soft tissue.

An oral diagnosis method for establishing an oral diagnosis neural network model

The application relates to the technical field of oral cavity diagnosis, in particular to an oral cavity diagnosis method for establishing an oral cavity diagnosis neural network model, which comprises the following steps: collecting oral cavity CT, endoscope hard tissue three-dimensional coordinates, soft tissue color parameters, tooth surface texture gray value parameters, checking and removing abnormal values to generate an oral cavity standardized original data set, extracting features and assigning weights to generate a weighted signal set, iteratively training to obtain diagnosis network weight parameters, calculating lesion matching degrees, dividing grades to establish oral cavity lesion quantitative grading data, in the application, oral cavity hard tissue three-dimensional coordinates, soft tissue color parameters and tooth surface texture gray value parameters are collected, values exceeding the normal physiological range are checked and removed to generate a standardized data set, features are extracted, converted into discrete signals and assigned with degree of distinction weights, stable diagnosis criteria are established through hierarchical transmission calculation and iterative training, accurate positioning and quantitative grading of oral cavity lesions are realized, and the diagnosis precision, efficiency and result consistency are greatly improved.
Owner:SHANXI MEDICAL UNIV

A tooth three-dimensional reconstruction method and device based on multi-view geometric prior and mirror Gaussian representation

PendingCN122134946AImage analysisOthrodonticsHigh reflectivityHard tissue
This invention provides a method and apparatus for 3D tooth reconstruction based on multi-view geometric priors and specular Gaussian representation. The method first acquires multi-view image data containing teeth and gingiva. A multi-view geometric estimation module predicts and globally aligns dense 3D point maps to obtain an initial point cloud, camera intrinsic and extrinsic parameters, and a depth map. Based on this, a Gaussian primitive set is initialized and input into a specular Gaussian reconstruction module, where relevant parameters are combined to optimize the reconstruction. This module introduces depth and normal losses based on the color target, supervises and reduces the weight of highlight regions within the region of interest, and finally outputs the 3D reconstruction result. This invention can improve the stability and geometric accuracy of tooth reconstruction under high reflectivity and weak texture, enhance specular reflection and highlight expression capabilities, and balance the detailed reconstruction of tooth hard tissue with the geometric and appearance effects of gingival soft tissue, thereby improving the integrity of oral scene reconstruction and its clinical application value.
Owner:NANJING STOMATOLOGICAL HOSPITAL

Animal phantom for radiation analysis and testing and the method of making thereof

PendingPH12024050921A1Radiology studiesHard tissue
This invention provides a hybrid manufacturing assembly of anatomical and workflow procedure in fabricating radiologically accurate animal phantoms. A method in which by utilizing additive manufacturing and molding technologies to fabricate the soft tissue, lungs, and hard tissue phantom of animal of interest and a way to assemble the organs such a radiologically heterogeneous phantom and structure is created and with the option to add provisions for radiological dosimetry devices is provided. The specified workflow is intended to address the need for low to medium volume production of small animal phantoms.
Owner:DEPARTMENT OF SCIENCE & TECHNOLOGY METALS INDUSTRY RESEARCH & DEVELOPMENT CENTER (DOST MIRDC) +1

Delivery of radiation for dental hard tissue treatment

PendingUS20260183092A1Dental CuringHard tissue
Embodiments relate to a systems and methods for preventative irradiative dental treatment. In accordance with one embodiment, a system and method include using a radiation source to generate a radiation; using an optic disposed to accept the radiation to internally reflect he radiation at a first end; using at least one side of the optic to contact a dental hard tissue; using the optic to couple some of the radiation into the dental hard tissue; and, using a controller to control a parameter of the radiation to heat a surface of the dental hard tissue.
Owner:ENAMEL PURE TECHNOLOGIES LLC

An embedding device for easy fixation of hard tissue

ActiveCN224435925UChemical reactionFixation method
This invention belongs to the field of hard tissue pathology slide preparation technology and discloses an embedding device for easy fixation of hard tissue. It includes an embedding layer with a curling deformation function, and several fixing units are provided on one side of the embedding layer. When the embedding layer is curled into a ring, the fixing units surround the hard tissue and compress and fix it. This invention uses the curling deformation of the embedding layer to drive the fixing units to distribute around the hard tissue, compressing and fixing it. The embedding layer is placed in an embedding bottle to maintain its curled shape. This fixation method is simple and convenient, and can fix biological bone tissue in the desired position and direction. The embedding layer and fixing units are made of polypropylene, which has stable chemical properties, is not prone to chemical reaction with the embedding liquid, and has relatively soft physical properties, making it less likely to cause defects in the embedded block. It also does not affect subsequent cutting, deplasticizing, or other processes.
Owner:DPW (SHANGHAI) BIOTECHNOLOGY CO LTD

A method for identifying bone layers in a hard tissue surgery

The application provides a bone layer identification method in hard bone tissue surgery, establishes a finite element simulation model of hard bone tissue surgery operation, carries out geometric modeling on the hard bone tissue, discretizes the hard bone tissue into finite element grids, defines material properties of the hard bone tissue, introduces constraint conditions of the operation process into the finite element model, obtains corresponding interactive force changes according to different parameters, collects real-time interactive force signals of the surgery tool and the hard bone tissue, selects multiple different types of bone layer features for the interactive force signals, then obtains force interaction curves through the finite element simulation model, establishes a Gaussian mixture model to describe distribution conditions of the different bone layer features, and trains the network model so that the network model can accurately identify different bone layers. The application solves the identification of the cortical bone and the cancellous bone in the hard bone tissue surgery process.
Owner:BEIJING INST OF TECH

A plant quarantine tissue sectioning device

This invention relates to the field of tissue sectioning and sampling technology, and discloses a tissue sectioning device for plant quarantine. The device includes a hand-cranked drive assembly, a piston flow control assembly, an adjustment assembly, a feedback deceleration assembly, and a transfer assembly. The lifting block is linked to the piston block through the piston rod, and during the cutting stroke, it pulsarily presses liquid into the liquid flow chamber next to the slicing blade, generating a pulsed liquid flow synchronized with the slicing rhythm, realizing non-contact guiding and transferring of the wax strip. When cutting hard plant tissue, causing a sudden increase in cutting load, the load increases the pressure in the piston cylinder and pushes the adjustment assembly to switch the flow path. The feedback deceleration assembly converts the pressurized liquid into a normal clamping force of the push block on the turntable, thereby increasing the torque required for the rocker wheel to continue rotating and reducing the risk of impact damage during the cutting of hard tissue. This invention organically combines pulsed liquid flow transfer with hydraulic resistance increase and deceleration, providing a slicing solution with strong sample protection for plant quarantine.
Owner:JIANGSU WOTIAN BIOTECHNOLOGY CO LTD +1

A composite material for bionic repair of dental hard tissue, a preparation method and application thereof

PendingCN122272376Ahigh affinityincrease concentrationEnamel rodHard tissue
This invention relates to the field of biomaterials technology, providing a composite material for biomimetic repair of dental hard tissues, its preparation method, and its application. The preparation method of the composite material includes the following steps: mixing a carboxybetaine-phosphonic acid copolymer with a calcium salt to obtain solution A; adding an aqueous phosphate solution to solution A to carry out an in-situ reaction to obtain the composite material for biomimetic repair of dental hard tissues. In the composite material provided by this application, the carboxybetaine-phosphonic acid copolymer, under the action of calcium phosphate ions, can form an amelogenin-like nanoribbon structure, simultaneously driving amorphous calcium phosphate to undergo supramolecular self-assembly, constructing a composite material conforming to the "self-assembly-mineralization" synergistic mode. This composite material can directionally deposit dense enamel-like enamel pillar structures of hydroxyapatite crystals on the surface of demineralized enamel, efficiently inducing oriented structural regeneration of damaged enamel and significantly restoring the mechanical properties of demineralized enamel.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Dental model set and multi-layered root canal therapy practice model

The application provides a tooth model set and a multi-layer root canal treatment exercise model, wherein the hard tissue part of the teaching tooth model is colorless and transparent printing material, and the soft tissue part is colored printing material. The hard tissue part of the pulp amputation exercise model is opaque 3D printing material, and the pulp part is colored printing material with a color different from that of the hard tissue part. The tooth crown part of the root canal treatment exercise model is opaque printing material, the tooth root part is colorless and transparent printing material, and the pulp part is colorless and transparent colloidal texture printing material. The tooth crown part of the multi-layer root canal treatment exercise model is opaque printing material, the tooth root part is colorless and transparent printing material, a translucent colored layer with a preset thickness is arranged near the pulp part of the tooth root part, and the pulp part is colorless and transparent colloidal texture printing material. The tooth model set provided by the application has a higher simulation degree of teeth and a more explicit simulation result display.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY

A multifunctional device for repairing defects of soft and hard tissues in oral cavity

ActiveCN117204974BDentistryMedical devicesTooth cariesHard tissue
The application discloses a kind of for repairing oral cavity soft and hard tissue defect multifunctional device in the field of medical devices, including inside hollow gingival cover, and a plurality of inside hollow tooth cover are integrally formed on gingival cover;A plurality of broken balls are placed in tooth cover, and casein phosphopeptide calcium phosphate complex is filled in broken ball;Through hole for the outflow of casein phosphopeptide calcium phosphate complex is opened on tooth cover;A plurality of occlusal parts are integrally formed on tooth cover, and the wear resistance of different occlusal parts is different;Elastic skeleton is integrally formed on the side wall of tooth cover, and elastic skeleton is made of a plurality of inside hollow and mutually connected parallelogram supports;A plurality of small holes are opened on elastic skeleton;Storage part is integrally formed in the middle of elastic skeleton, and storage part is communicated with elastic skeleton, and anti-inflammatory drug is filled in storage part;By constructing dental caries inhibition model, occlusal surface wear inhibition model and maxillofacial skin defect repair model, oral cavity soft and hard tissue defect can be multifunctionally repaired.
Owner:SICHUAN UNIV

An endoscope slam system and method based on viscoelastic model tissue perception

PendingCN122289536ARgb imageBiomechanics
This invention discloses an endoscopic 3DGS-SLAM method and system based on a viscoelastic model for tissue perception, belonging to the field of medical robot visual perception and 3D reconstruction technology. The physical-driven Kelvin-Voigt viscoelastic model is embedded in a 3D Gaussian splash representation framework. The input consists of an endoscopic RGB image sequence and a sparse depth map. By assigning learnable elastic and viscous coefficients to each Gaussian element and constructing a viscoelastic dynamic equation to control the scale and rotation updates of the Gaussian sphere, an accurate description of the complex biomechanical behavior of soft tissue is achieved. A multimodal driving signal fusion mechanism is designed, comprehensively utilizing five complementary signals—2D gradient, color change, position change, scale change, and projection radius—to calculate a unified driving field. Simultaneously, a soft and hard tissue classification algorithm based on multiple physical quantities is proposed to achieve adaptive step size control for tissue perception, employing differentiated update strategies for soft and hard tissues.
Owner:BEIJING UNIV OF TECH

A puncture path planning method, device, equipment and storage medium

PendingCN122297107A3d imageImage segmentation
This application provides a puncture path planning method, apparatus, device, and storage medium. The method includes: acquiring three-dimensional images of the puncture area at different phases within at least one respiratory cycle; determining the hard and soft tissues in each three-dimensional image through image segmentation; setting risk weights for hard and soft tissues in each three-dimensional image, with the soft tissue having a greater weight than the hard tissue; generating a heatmap for each three-dimensional image based on the risk weights; determining the location of the puncture area and the skin boundary in each three-dimensional image based on image features of the puncture area and skin boundary; fusing the locations of the puncture areas in each three-dimensional image to obtain the puncture starting point; selecting multiple candidate paths from the puncture starting point to each skin boundary in various directions; calculating the sum of risk weights for each candidate path in each heatmap; and selecting the optimal puncture path from the candidate paths based on the sum of risk weights and the length of each candidate path.
Owner:BEIJING GREAT ROBOTICS TECH LTD

Oral care composition comprising a dicarboxylic acid

PendingCN122318964AMalonic acidMouth care
An oral care composition comprising malonic acid or a salt thereof and iron, greater than 0 ppm to about 300 ppm by weight of the oral care composition. The oral care composition may contain about 0.1% to about 15% malonic acid or a salt thereof. The oral care composition provides effective control of oral hard tissue biofilm.
Owner:PROCTER & GAMBLE CO

Oral and maxillofacial three-dimensional model construction method based on oral soft and hard tissue identification

PendingCN122391566AAnatomical structuresVoxel
The present application relates to the technical field of oral and maxillofacial three-dimensional modeling processing, in particular to an oral and maxillofacial three-dimensional model construction method based on oral soft and hard tissue recognition, comprising: acquiring original three-dimensional voxel data of the oral and maxillofacial region of a patient containing gray value information, constructing a multi-scale feature field and calculating voxel feature gradient intensity, generating an adaptive boundary tracking grid according to the spatial distribution of the feature gradient intensity. In the grid node, the soft and hard tissue boundary energy is calculated by combining the voxel gray value and the feature gradient intensity, the boundary energy field is constructed and the force line propagation is simulated, the high-energy ridge line is extracted and the corresponding grid element is marked as a set of tissue boundary voxels to be classified, and the oral and maxillofacial three-dimensional model is generated by combining a pre-trained tissue attribute classifier. The method can adaptively match the gradient change at the junction of soft and hard tissues, accurately quantify the attribution degree of the voxels at the junction, improve the positioning accuracy and continuity of boundary recognition, and make the three-dimensional model more consistent with the actual anatomical structure of the oral and maxillofacial region.
Owner:SHANGHAI XUHUI DISTRICT DENTAL HOSPITAL (SHANGHAI XUHUI DISTRICT DENTAL DISEASE CONTROL & PREVENTION INSTITUTE)

A Denture Fabrication Method Based on Virtual Frame Data Interaction

PendingCN122075169ADental prosthetics3D modellingDenture DesignRelative motion
This invention provides a denture processing method based on virtual articulator data interaction, belonging to the field of denture processing technology. The method includes: acquiring a three-dimensional model of the patient's dentition and maxillofacial soft and hard tissues; collecting the relative movement trajectory and occlusal force distribution of the upper and lower jaws; generating a digital morphology of the patient's dentition based on the three-dimensional model; initially matching the positions of the upper and lower jaws in a virtual articulator system; simulating the opening and closing, lateral movements, and occlusal force distribution of the patient's upper and lower jaws in the virtual articulator system; establishing an initial contour based on the simulation results; performing simulation adjustments through a set of interference features; and managing denture processing. This invention solves the technical problem in existing technologies where denture design cannot fully consider the individualized oral movements and dynamic occlusal characteristics of patients, resulting in poor denture processing accuracy, comfort, and adaptability. It achieves optimized denture design and processing, effectively improving the accuracy, comfort, and adaptability of denture processing.
Owner:SHANDONG INNOWAY MEDICAL TECH CO LTD

Thulium-doped fiber laser therapy machine

ActiveCN310064376SHuman bodyThulium
1. Name of the product in this design: Thulium-doped fiber laser therapy machine. 2. Application of this design: for urinary tract lithotripsy and cutting and vaporizing of soft and hard human tissues. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.
Owner:SHANGHAI RAYKEEN LASER TECH CO LTD

Oral care composition comprising a dicarboxylic acid

A teeth whitening composition includes a chemical whitening agent, wherein the chemical whitening agent comprises malonic acid or a salt thereof. The teeth whitening composition may be free of, substantially free of, or substantially free of polyphosphates. A method of whitening teeth includes applying the teeth whitening composition to teeth and removing the teeth whitening composition from the teeth. This teeth whitening composition provides effective whitening of oral hard tissues with fewer of the drawbacks observed with other whitening agents.
Owner:PROCTER & GAMBLE CO

A protein matrix composition for hard and soft tissue matrix repair, reconstruction, and / or augmentation

PCT designated stageWO2026042053A8Pharmaceutical delivery mechanismUnknown materialsTissue architectureBiochemistry
The current invention involves a method of mixing POP with a tissue matrix to obtain a matrix composition for soft and hard tissue matrix repair, reconstruction, and / or augmentation. POP is a partially ordered polypeptide and the tissue matrix is a decellularized tissue matrix derived from a source tissue. The invention involves mixing these compositions in a matrix composition and implanting or injecting the matrix composition into a subject to repair, augment, or reconstruct a tissue structure.
Owner:INSOMA BIO INC +3

An irregularly shaped surgical knife with a grinding and drilling function

PendingCN122075076AIncision instrumentsDiagnosticsBone tissueHard tissue
This invention relates to the field of scalpel technology, and in particular to a non-standard scalpel with a grinding and drilling function, comprising a scalpel handle and a scalpel head. The scalpel head is assembled inside the scalpel handle, which contains a disassembly assembly including a device slot. Through the design of the trigger assembly, when the scalpel head contacts soft tissue, a ring-shaped protective sleeve extends forward under the action of a third spring to cover the cutting edge, forming a rounded working surface to protect the tissue. When bone tissue needs to be treated and greater pressure is applied, the reaction force of the bone surface automatically pushes the protective sleeve backward to expose the cutting edge. This purely mechanical trigger design ensures that the switching of working modes is completely controlled in real time and automatically by the force applied to the surgical end, eliminating the need for the surgeon to be distracted. This effectively avoids accidental damage to soft tissue and ensures high efficiency in treating hard tissue, thereby achieving intelligent and safe operation with a single instrument.
Owner:SHANGHAI RUICHANG MEDICAL TECHNOLOGY CO LTD

Bi-directional disk removal and decortication tool

PendingUS20260151140A1Endoscopic cutting instrumentsAbrasive surgical cuttersDecorticationHard tissue
The present disclosure provides a cutting tool for surgical procedures. More specifically, the present cutting tool is suitable for bi-directional cutting and removal of soft and hard tissues for surgical procedures. The cutting tool includes a substantially rigid shaft having a shaped end portion. The shaped end portion includes a plurality of shaped talons; each talon including a body bent to retain tissue, and each talon including a cutter end. The cutter end includes both acute and obtuse cutting surface relief angles for diverse cutting action with respect to hard and soft tissues.
Owner:GLOBUS MEDICAL INC

Glass-ceramic dental crown and method for manufacturing same

PendingCN122351027ANatural toothSilicic acid
The application discloses a glass ceramic dental crown and a preparation method thereof, and relates to the technical field of glass ceramic dental crown. The preparation method adopts lithium disilicate as a base material, and is combined with rare earth doped hydroxyapatite and functional crystals. By accurately controlling the synergistic ratio of each component, the unity of mechanical properties, biological adaptability and aesthetic effect is realized. The rare earth doped hydroxyapatite is prepared by a hydrothermal precipitation method, the dispersion effect of trisodium citrate is used to inhibit particle agglomeration and promote the interface combination with human hard tissues; and the rare earth doped fluorescent powder is used to construct monodisperse light emitting centers by controlling a rare earth ion doping process, so that concentration quenching is avoided, and the fluorescent properties close to natural teeth are given to the dental crown.
Owner:SHANXI MEDICAL UNIV +1