144 results about "Hard tissue" patented technology

Devices, systems, and methods for predicting palatal geometry are provided. In some embodiments, a system for predicting an anatomy of a patient's palate includes one or more processors and a memory operably coupled to the one or more processors and storing instructions that, when executed by the one or more processors, cause the system to perform operations including accessing a first digital representation including an initial geometry of soft tissue corresponding to a patient's palate, determining an initial geometry of hard tissue of the patient's palate, predicting a change in the hard tissue during a treatment, using the predicted change in the hard tissue to predict a change in the soft tissue during the treatment, and outputting a second digital representation including a predicted geometry of the patient's palate at a future treatment stage of a treatment plan, based on the predicted change in the soft tissue.

The invention relates to the technical field of information, and particularly provides a complete denture arrangement virtual simulation method and system, and the method comprises the steps: obtaining the medical record data of a user; the medical record data comprises edentulous jaw soft and hard tissue data, jaw bone data, alveolar ridge morphological parameters, jaw position relation data and facial feature data; determining an initial dental arch curve based on the medical record data; inputting the initial dental arch curve and preset aesthetic parameters into a preset deep learning model to obtain a plurality of initial tooth arrangement schemes; screening the plurality of initial tooth arrangement schemes according to tooth arrangement constraint conditions to obtain tooth arrangement schemes meeting constraints; the tooth position and angle of each tooth arrangement scheme meeting the constraint are adjusted until the preset occlusion balance condition is met, and the first tooth arrangement scheme is obtained, so that the tooth arrangement scheme efficiency of the complete dentures can be improved on the premise that the quality of the tooth arrangement scheme of the complete dentures is guaranteed.

The invention provides a laser oral cavity therapeutic instrument which comprises a therapeutic instrument body, a laser generation assembly, a water vapor nozzle assembly and a gas-liquid-electricity external connection assembly, the laser generation assembly, the water vapor nozzle assembly and the gas-liquid-electricity external connection assembly are arranged in the therapeutic instrument body, and the laser generation assembly is used for generating a high-energy laser beam; the oral cavity treatment is performed through the high-energy laser beam; the water vapor spray head assembly is used for forming water vapor spray so as to cooperatively clean or cool the oral cavity; the gas-liquid-electricity external connection assembly is used for connecting external gas, water and electric signals so as to ensure normal work of the laser oral cavity therapeutic instrument. The laser generating assembly, the steam spray head assembly and the gas-liquid-electric external connection assembly are arranged in the therapeutic instrument body, the laser generating and emitting function and the steam mixing and cooling function are integrated into one structure, the operation requirements of basic decontamination and sterilization, soft and hard tissue cutting, bone tissue removal and the like are met, and meanwhile the therapeutic instrument has the advantages of being high in integration degree, reasonable in structure, convenient to operate and the like.

The application relates to the technical field of oral cavity diagnosis, in particular to an oral cavity diagnosis method for establishing an oral cavity diagnosis neural network model, which comprises the following steps: collecting oral cavity CT, endoscope hard tissue three-dimensional coordinates, soft tissue color parameters, tooth surface texture gray value parameters, checking and removing abnormal values to generate an oral cavity standardized original data set, extracting features and assigning weights to generate a weighted signal set, iteratively training to obtain diagnosis network weight parameters, calculating lesion matching degrees, dividing grades to establish oral cavity lesion quantitative grading data, in the application, oral cavity hard tissue three-dimensional coordinates, soft tissue color parameters and tooth surface texture gray value parameters are collected, values exceeding the normal physiological range are checked and removed to generate a standardized data set, features are extracted, converted into discrete signals and assigned with degree of distinction weights, stable diagnosis criteria are established through hierarchical transmission calculation and iterative training, accurate positioning and quantitative grading of oral cavity lesions are realized, and the diagnosis precision, efficiency and result consistency are greatly improved.

There is provided a kit for performing socket shield technique, and methods for using the kit, wherein the kit may include a wheel bur, having a first working surface disc and a second working surface disc configured to smoothen and cut hard tissues of a tooth; one or more trephine burs with stoppers configured to cut a root canal to create a first tooth fragment and a second tooth fragment, wherein each stopper is compatible with each of the one or more trephine burs; a root fragment remover configured to extract the first tooth fragment and stabilize the second tooth fragment; a split end elevator having a v-shaped notch tip configured to remove the first tooth fragment; a cylindrical bur to control the thickness of the second root fragment; and a round bur configured to separate the second root fragment from unwanted fragments.

This invention provides a method and apparatus for 3D tooth reconstruction based on multi-view geometric priors and specular Gaussian representation. The method first acquires multi-view image data containing teeth and gingiva. A multi-view geometric estimation module predicts and globally aligns dense 3D point maps to obtain an initial point cloud, camera intrinsic and extrinsic parameters, and a depth map. Based on this, a Gaussian primitive set is initialized and input into a specular Gaussian reconstruction module, where relevant parameters are combined to optimize the reconstruction. This module introduces depth and normal losses based on the color target, supervises and reduces the weight of highlight regions within the region of interest, and finally outputs the 3D reconstruction result. This invention can improve the stability and geometric accuracy of tooth reconstruction under high reflectivity and weak texture, enhance specular reflection and highlight expression capabilities, and balance the detailed reconstruction of tooth hard tissue with the geometric and appearance effects of gingival soft tissue, thereby improving the integrity of oral scene reconstruction and its clinical application value.

The utility model belongs to the technical field of animal waste, and particularly relates to an animal waste harmless treatment system which comprises a frame, a drying device is arranged on the outer surface of the frame, the drying device comprises an electric heating wire, the electric heating wire is started to dry the waste, and a grinding device is arranged to grind the waste so as to grind the waste. The grinding motor drives the rotating rod to rotate, the rotating rod is rotationally connected with the grinding roller, rotation of the grinding roller is not affected while the grinding roller is driven to revolve, and the rotating gear fixedly installed on the grinding roller is meshed with the gear ring fixedly installed on the grinding frame to enable the grinding roller to rotate, so that the waste grinding efficiency can be improved, and the problems that in the prior art, bones are hard tissues, and the grinding efficiency is poor are solved. Large bone blocks and skeletons need to be completely degraded or decomposed for a long time, and the overall waste treatment efficiency is remarkably affected.

The invention provides a porous biological ceramic hard tissue slice as well as a preparation method and application thereof. The preparation method of the porous biological ceramic hard tissue slice comprises the following steps: preparing a hydroxyl phospholime bone restoration specimen; dehydrating and transparentizing the hydroxyapatite bone restoration specimen; carrying out permeation and embedding on the hydroxyl phospholime bone restoration specimen; carrying out block trimming and slicing on the hydroxyl phospholime bone restoration specimen; mounting the hydroxyl phospholime bone restoration specimen; through the five steps, the porous biological ceramic hard tissue slice is obtained. According to the method, the defect that a tissue-material structure is easy to damage when a biological ceramic material is treated by a traditional hard tissue slicing technology is overcome; the improved hard tissue slicing technology is suitable for research of biological ceramic materials in bone tissue engineering application.

A device for mechanical securement to hard tissue of a subject, the hard tissue having an end surface defining a direction of curvature such that over at least a portion of the surface, a total curvature of at least 180 degrees is defined, the device comprising a body portion comprising at least four contact points, three contact points of the four contact point span over 180 degrees of total curvature of the end surface in a plane defined by the three contact points, and a fourth contact point outside the plane, the four contact points providing mechanical securement of the body portion to the hard tissue.

The invention discloses a dismounting and mounting structure and a repeatable loading clamp device, and belongs to the technical field of medical instruments. The dismounting and mounting structure comprises a clamp seat and a conveying seat which are detachably connected; the conveying seat is connected with a sheath tube of the conveying device, a moving channel is arranged in the conveying seat, an inner core is arranged in the moving channel, the near end of the inner core is connected with an inhaul cable, and a connecting plug is arranged at the far end of the inner core and comprises an expansion section and a necking section; a mounting channel is formed in the clamp seat, a connecting pull piece is arranged in the mounting channel, the far end of the connecting pull piece is connected with the hemostatic clamping piece, an insertion opening is formed in the near end of the connecting pull piece, a mounting area, a limiting area and a releasing area are arranged in the mounting channel, the mounting area and the releasing area allow the insertion opening to be opened in the radial direction for the expansion section to pass through, and the limiting area is used for limiting the insertion opening; the repeatable loading clip device comprises a hemostatic clip piece, a conveying device and a disassembly and assembly structure. In different positions, the clamp can be quickly mounted and released, and the hemostatic clamping piece can reliably clamp and close tissues with larger wounds, harder tissues and scabbed tissues.

The invention discloses nano calcium polyphosphate-containing toothpaste with a repairing effect and a preparation method of the nano calcium polyphosphate-containing toothpaste. The toothpaste is prepared from the following components in percentage by mass: 5 to 15 percent of water, 55 to 75 percent of a polyol humectant, 0.2 to 1 percent of sodium carboxymethyl cellulose, 2 to 8 percent of sodium lauryl sulfate, 15 to 20 percent of silicon dioxide, 0.01 to 0.4 percent of menthol, 0.01 to 0.07 percent of a preservative and 0.01 to 0.1 percent of nano calcium polyphosphate. The nano calcium polyphosphate is introduced into a toothpaste system, and the nano calcium polyphosphate can be effectively attached to and actively repair microscopic defects on the enamel surface by utilizing the high specific surface activity and biomimetic mineralization characteristics of the nano calcium polyphosphate. The toothpaste not only has a conventional cleaning function, but also can remarkably reduce tooth surface roughness, recover microhardness and relieve dentin sensitivity, daily active repair of tooth hard tissue is achieved, and the defect of existing toothpaste in the aspect of direct structural repair is overcome.

The invention discloses a double-layer GBR membrane for promoting soft and hard tissue repair and a preparation method and application thereof, and is applied to the field of medical materials. The double-layer GBR membrane mainly comprises an acellular dermal matrix obtained by decellularizing fetal calfskin and a piezoelectric layer prepared by electrostatic spinning of poly-L-lactic acid and chitosan, and the acellular dermal matrix and the piezoelectric layer are further combined through a polydopamine coating prepared on the surface of the piezoelectric layer. During application, the acellular dermal matrix side faces the soft tissue side, and the piezoelectric layer faces the bone tissue side, so that the acellular dermal matrix skin side which is compact in structure is in contact with the soft tissue to play a barrier role, and the relatively loose piezoelectric layer is in contact with bone defects to play a role in guiding osteoblasts to adhere; functionally, soft tissue repair is promoted through the angiogenesis promoting effect of the acellular dermal matrix and the similarity of the tissue of the acellular dermal matrix, and bone regeneration of a bone defect area is promoted through the piezoelectric osteogenesis and angiogenesis effects of the piezoelectric layer.

This invention discloses a self-assembled joint implant integrating hard and soft tissue and its forming method. The implant comprises two parts: a hard tissue structure and a soft tissue structure. The hard tissue structure includes a dense hard tissue structure and a porous, loose hard tissue structure with a bidirectional gradient porosity. The soft tissue structure includes a hard soft tissue structure and a soft soft tissue structure, with different ratios of hydroxyapatite and hydrogel. The contact surfaces of the hard and soft tissue structures have corresponding serrated structures, achieving stable assembly through a combination of interference fit and friction. Furthermore, the hard tissue undergoes surface modification and is combined with a binder to promote the stability of the hydrogel applied before and after assembly, improving the firmness of the soft-hard tissue bond. The overall structure and materials of this invention exhibit continuous gradient continuity, enabling a stable transition of properties at various interfaces and reducing instability, thereby promoting post-implantation recovery and preventing loosening.

This invention provides a hybrid manufacturing assembly of anatomical and workflow procedure in fabricating radiologically accurate animal phantoms. A method in which by utilizing additive manufacturing and molding technologies to fabricate the soft tissue, lungs, and hard tissue phantom of animal of interest and a way to assemble the organs such a radiologically heterogeneous phantom and structure is created and with the option to add provisions for radiological dosimetry devices is provided. The specified workflow is intended to address the need for low to medium volume production of small animal phantoms.

An electroactive titanium support-reinforced composite film includes a titanium support and a film material coating the titanium support. The titanium support has a structure designed according to securing sites. The electroactive titanium support-reinforced composite film of the present invention can be bent and shaped for a close fit with a hard tissue, has excellent mechanical performance and a stable electroactive bending strength of bionic magnitude, and can prevent the collapse of surrounding tissues and tissue adhesion, effectively maintain a three-dimensional space for bone osteanagenesis and effectively promote bone injury healing, featuring ease and convenience of clinical operation and capability of promoting bone marrow mesenchymal stem cell adhesion, cytoskeleton rearrangement and induced osteogenic differentiation. The support-reinforced composite film is suitable for mandible or cranium injury repair in different ranges and has significant efficacy for clinical indications such as alveolar bone vertical bone augmentation and alveolar ridge preservation after tooth extraction.

The present invention relates to a laser surgical system for cutting hard tissue on an object, comprising a handheld laser applicator, a collaborative robot with a robot arm to which the handheld laser applicator is attached, a navigation system with which the instantaneous position of the laser applicator relative to the object can be detected, and a controller for the collaborative robot. The laser applicator has a measuring device with which the cutting depth of a kerf produced by a processing laser beam and the residual thickness of the hard tissue in the kerf can be measured.The control system directs the collaborative robot during the execution of a cut based on data from the navigation system and the measuring device in such a way that it maintains a cutting distance of the laser applicator to the object required for cutting via the robot arm and only allows a feed movement of the laser applicator along a cutting line by the operator when a cut that has just been carried out is completely finished.

The invention relates to the field of oral digitization, and provides a three-dimensional form automatic reconstruction method and system for a mandible defect. The method comprises the following steps: importing CBCT image data of a patient with the mandible defect into three-dimensional reconstruction software, and extracting hard tissues of the mandible through threshold segmentation to obtain three-dimensional data of the mandible defect; obtaining structured mandible three-dimensional template data; performing size normalization and initial alignment on the structured mandible three-dimensional template data and the mandible defect three-dimensional data to obtain initial alignment template data; gradually deforming and registering the initial alignment template data to the mandible defect three-dimensional data based on a non-rigid registration algorithm added with symmetry constraint to obtain template deformation registration data; and outputting the template deformation registration data as a mandible defect three-dimensional reconstruction result. According to the method, the automation degree and efficiency of three-dimensional reconstruction of the mandible defect are improved.

Embodiments relate to a systems and methods for preventative irradiative dental treatment. In accordance with one embodiment, a system and method include using a radiation source to generate a radiation; using an optic disposed to accept the radiation to internally reflect he radiation at a first end; using at least one side of the optic to contact a dental hard tissue; using the optic to couple some of the radiation into the dental hard tissue; and, using a controller to control a parameter of the radiation to heat a surface of the dental hard tissue.

The present invention relates to a surgical laser system for cutting hard tissue on an object (19), comprising a hand-guidable laser applicator (18), a collaborative robot (34) having a robot arm (36) to which the hand-guidable laser applicator (18) is fastened, a navigation system (41) by means of which a respective current position of the laser applicator (18) relative to the object (19) can be detected, and a controller (42) for the collaborative robot (34). The laser applicator (18) has a measuring device (7) by means of which a cutting depth of a kerf produced by a machining laser beam (2) and a residual thickness of the hard tissue in the kerf can be measured. While the cut is being made, the controller (42) controls the collaborative robot (34) on the basis of data of the navigation system (41) and the measuring device (7) in such a way that the collaborative robot, via the robot arm (36), maintains a cutting distance, required for cutting, of the laser applicator (18) from the object (19), and allows an advancing movement of the laser applicator (18) along a cutting line by the surgeon to be carried out only when a cut that has just been made has been completed.

The invention discloses a preparation method and application of a graded delivery system which takes a pH response type metal organic framework material NH2-MIL-101 (Fe) as a carrier and takes antibacterial peptide AMP and irisin as active ingredients. The graded delivery system comprises a metal organic framework material NH2-MIL-101 (Fe), AMP (adenosine monophosphate) and Irisin, wherein the AMP and the Irisin are loaded on the pH (potential of hydrogen) response type metal organic framework material NH2-MIL-101 (Fe). According to the system, aiming at periodontal and dental pulp infectious diseases, early-stage AMP rapid release for precise bacteriostasis and middle-stage Irisin synergistic release are realized through time sequence regulation and control to achieve anti-inflammatory and anti-oxidation effects, so that alveolar bone tissue / dentin regeneration is further promoted, and an excellent'antibacterial-anti-inflammatory-hard tissue regeneration 'cascade treatment effect is shown. The invention provides a new strategy and theoretical basis for precise treatment of periodontitis and pulpitis.

A suture anchor includes a material having thermoplastic properties and is fixated in a hard tissue opening by liquefying at least part of this material and letting it penetrate into walls of the hard tissue opening. During the named fixation and preferably towards the end of it, the suture being held in a distal suture conduit is locked relative to the hard tissue by being clamped between the suture anchor and the wall of the hard tissue opening or by being clamped or braked through collapse of the suture conduit.

Fibrinogen-coated Albumin Nanospheres (FAS) has shown that it can mobilize bone marrow cells into the blood which then go to injured soft and hard tissues to achieve accelerated repair. It is hypothesize that (a) brain injuries caused by low-dose irradiation under simulated microgravity can be mitigated by the administration of FAS; and (b) the mechanism is from acceleration of neo-vascularization, proven by lineage study of GFP-labeled bone marrow cells implanted into compatible non-GFP animals before injury, which regenerate into functional GFP-brain cells after FAS treatment.

To provide a laser system for enhancing remineralization and strength of hard tissue.SOLUTION: A laser-based system and method for treatment of hard tissue enhances remineralization and fluoride uptake to improve resistance to demineralization. The system can include a laser source, an optic, and a controller for controlling the laser source and / or the optic to deliver radiation to a treatment region with desirable characteristics (e.g., to remove carbonate without damaging the tissue surface). In some cases, the system includes a handpiece having an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam to render the beam non-ablative, prior to the laser beam's delivery to the treatment region. In some embodiments, treatment with the laser can be combined with a fluoride treatment for enhanced therapeutic effect.SELECTED DRAWING: Figure 1

According to an embodiment a combined hard and / or soft tissue medical implant may be provided for orthopedic and neurosurgical management of disease. The medical implant may further include an integrated reservoir, embedded pump-assisted smart technology, a strategic high-profile port for easy and safe access just underneath the neighboring skin, and one or more embedded catheters to deliver medication or cellular therapies.

The invention relates to the technical field of biomedical materials, in particular to a tooth hard tissue regeneration material and a preparation method thereof. The dental hard tissue regeneration material is prepared from the following raw material components in parts by weight: 2 to 3 parts of CA-PEGDGE / PLL, 2 to 3 parts of quercetin-icariin, 4 to 6 parts of chitosan, 1.5 to 2 parts of hydroxyapatite and 0.4 to 0.6 part of P24 polypeptide.

1. The name of the design product: laser treatment instrument. 2. The use of the design product: the design product is used for laser treatment of soft tissue, hard tissue and bone tissue, sterilization and physiotherapy. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

1. Name of the product in this design: Thulium-doped fiber laser therapy machine. 2. Application of this design: for urinary tract lithotripsy and cutting and vaporizing of soft and hard human tissues. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention discloses a wrinkled-fruit-shaped biological ceramic particle-based composite material as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. The preparation method comprises the following steps: mixing 5-15% by weight of biological ceramic particles and 85-95% by weight of microfiber gel, and homogenizing at a high speed to obtain the composite material. According to the wrinkled-fruit-shaped biological ceramic particle-based composite material provided by the invention, the biological ceramic particles and the microfiber gel are combined, so that the wrinkled-fruit-shaped biological ceramic particle-based composite material not only has good biocompatibility, but also can promote cell adhesion and tissue regeneration at the combination part of soft and hard tissues. The composite material is particularly suitable for repairing tendon injury and can effectively promote regeneration of tendons and tendon bone dead points.

The present application is based on the anatomical features of oral periodontal alveolar bone tissue and the regeneration speed difference of soft and hard tissues, and provides a method for preparing a gradient biomimetic scaffold including a soft tissue layer, a barrier layer and a hard tissue layer by using coaxial electrospinning technology. The gradient biomimetic scaffold exhibits good mechanical properties and biocompatibility. Among them, the gradient distribution of the soft tissue layer can induce the adhesion and regeneration of fibroblasts, the barrier layer at the interface can prevent fibroblasts from invading the osteogenic layer, and the hard tissue layer can induce the differentiation and regeneration of osteoblasts. The gradient biomimetic scaffold prepared by the present application can be used as an excellent guided oral soft and hard tissue combined repair material, and has a broad application prospect in oral medicine.

The invention discloses a multi-material gradient bionic dental crown and a digital preparation method thereof, and belongs to the technical field of dental restoration materials and digital additive manufacturing. Comprising a dental crown body, the dental crown body is provided with a material structure of which the mechanical property continuously changes in a gradient manner along with the surface of a prepared tooth body, is formed by mixing two basic resin materials through voxel-level gradient in space, and is divided into two functional layers by imitating a double-layer hard tissue physiological structure of a natural tooth; comprising a high-wear-resistance bionic enamel layer used for forming the outer surface of a dental crown body and a high-toughness bionic dentin layer used for forming the dental crown body and connecting the high-wear-resistance bionic enamel layer and the surface of a prepared tooth body. By simulating a gradient structure of a natural tooth and a crack inhibition mechanism of the enamel-dentin boundary (DEJ), the fracture toughness and the anti-fatigue life of the dental crown body are far better than those of a traditional single-layer or layered all-ceramic crown, and thermal stress and mechanical stress are effectively buffered through modulus matching of the high-toughness bionic dentin layer and a resin adhesive.