92 results about "Periodontium" patented technology

The invention discloses an adhesive hydrogel for oral periodontal tissue regeneration and a preparation method thereof, gelatin and polyacrylic acid are used as main raw materials, and a photo-crosslinking method is used as a basis to prepare the adhesive hydrogel; the adhesive hydrogel has good tissue adhesion, can be tightly adhered to wet soft and hard tissue surfaces, and overcomes the defect that the oral periodontal filling material is difficult to fix clinically at present. The adhesive hydrogel has high porosity after completely absorbing water and swelling, and pores in the surface and inside of the adhesive hydrogel are communicated with each other, so that the adhesive hydrogel can provide more space for growth of oral periodontal tissues, and is suitable for ingrowth of cells and regeneration of the oral periodontal tissues.

A method for measuring periodontal disease and treating diseases associated therewith includes: obtaining B-mode ultrasound images of a dentition and periodontium of a patient; identifying gingival margin (GM), alveolar bone crest (ABC), cementoenamel junction (CEJ), periodontal ligament (PDL), and gingival edge (GE) biomarkers on the B-mode ultrasound images, the GE biomarker being a part of periodontal soft tissue most distal from a tooth surface; evaluating a metric associated with periodontal disease using one or more of the GM, ABC, CEJ, PDL and GE biomarkers and based at least in part on the evaluating, performing an act that implements and / or adjusts a therapeutic treatment of a periodontal disease.

The utility model discloses a drug delivery tooth socket which comprises a tooth socket body, the tooth socket body is provided with a lip side face, a tooth groove and mounting holes communicated with the tooth groove, and the tooth socket body is provided with a plurality of mounting holes in the extension direction of the lip side face; a medicine storage cavity capable of storing medicine and a release hole communicated with the medicine storage cavity are formed in the medicine storage bag, and the medicine storage cavity is communicated with the outside through the release hole; the medicine storage bag is detachably connected with the mounting holes, and when the medicine storage bag is connected with one of the mounting holes, the release hole is communicated with the tooth socket through the mounting hole, so that the time that the medicine is attached to teeth and periodontium can be effectively prolonged, and the treatment effect of the medicine on an affected part is improved.

The invention discloses a dental pulp stem cell-derived exosome photocuring hydrogel and a preparation method and application thereof in treating severe periodontitis, and the dental pulp stem cell-derived exosome photocuring hydrogel has better biocompatibility and capability of promoting periodontal tissue regeneration by utilizing the dental pulp stem cell-derived exosome; the sustained-release effect of the hydrogel is beneficial to continuously providing treatment components and reducing the treatment times; through local administration, systemic side effects are reduced, and the safety and effectiveness of treatment are improved.

The invention relates to the technical field of oral cavity treatment instruments, and provides an oral cavity multi-professional endoscope and an image artificial intelligence processing auxiliary diagnosis method. The multi-specialty endoscope for the oral cavity comprises an insertion part, an operation part, a signal line and light-guide fibers, the front end of the operation part is connected with the insertion part, the front end of the insertion part is provided with an image acquisition element, the image acquisition element is connected with the signal line, and the signal line is connected with the host; a light source is arranged in the operation part or the main machine, and when the light source is located in the main machine, light is transmitted to the insertion part through the optical fiber; the lens tube of the insertion part is in a hook shape, a bent shape, a straight rod shape or other shapes capable of being observed. According to the embodiment of the invention, fine structures of oral tissues such as tooth pulp cavity root canal, periodontium, implant cavity and salivary gland catheter can be directly examined.

The invention relates to a dynamic simulation method and system for a tooth movement process based on a Type model, and the method comprises the steps: carrying out the data collection of an artificial tooth and a fixed appliance through three-dimensional scanning, and obtaining the three-dimensional data of a tooth jaw structure; performing overlap analysis on the crown root model according to the three-dimensional data to obtain a digital dental model containing periodontal tissues; performing material attribute assignment on an anatomical structure in the digital tooth jaw model according to preset material parameters to obtain a biomechanical tooth jaw model; and performing time recursion iteration on the biomechanical tooth jaw model through finite element analysis to obtain four-dimensional dynamic simulation data for simulating a tooth movement process, so as to provide visual orthodontic process teaching demonstration based on the four-dimensional dynamic simulation data. According to the invention, the dynamic visual simulation of the tooth movement process is realized, the feedback of the Type Dont system can be quantified, and the teaching interactivity is improved.

The invention discloses a comprehensive oral diagnosis and treatment system, which relates to the technical field of oral medicine and medical instruments and comprises a tooth movement monitoring module, a low-intensity pulsed ultrasound module, a high-intensity focused ultrasound module, a blood flow monitoring module, a control module, a wireless communication module and a terminal module. According to the invention, comprehensive monitoring and treatment of tooth movement, periodontal tissue health, temporomandibular joint function and oral cavity related muscle dynamics of a patient can be realized. Meanwhile, the equipment integrates advanced low-intensity pulsed ultrasound and high-intensity focused ultrasound technologies, and has the functions of periodontal tissue repair, muscle relaxation and joint soft tissue treatment. Besides, through the wireless communication module and the terminal module, the system can provide real-time health data monitoring and personalized diagnosis and treatment schemes, and is widely suitable for patients with orthodontics, periodontal diseases, temporomandibular joint disorder and other related oral dysfunctions.

The invention discloses a combined lactobacillus salivarius CCFM1397 for improving osteoblast activity and relieving bone resorption and periodontal tissue damage and a metagen thereof, and belongs to the technical field of microorganisms. The lactobacillus salivarius combination CCFM1397 provided by the invention is separated from oral dental plaque of healthy teenagers, has the effects of relieving bone resorption and resisting inflammation, and is specifically reflected in that: the expression of MC3T3-E1 cell osteoprotegerin (OPG) protein and gene level is improved in vitro; the bone absorption amount of orthodontic bone absorption rat alveolar bone is reduced, the number of alveolar bone osteoclasts is reduced, and the level of rat serum OPG is improved; the secretion of inflammatory factors IL-1beta, IL-6 and TNF-alpha and myeloperoxidase MPO of the orthodontic bone absorption rats is reduced; and the pathological condition of orthodontic bone absorption rat alveolar bone tissue is improved. Therefore, the combined lactobacillus salivarius has a huge application prospect in products for relieving bone resorption and assisting in inhibiting periodontal tissue inflammation.

The invention relates to the technical field of dental oral treatment, and discloses a repair method for treating periodontitis by using dental pulp stem cells, which comprises the following steps: S1, extracting dental pulp tissues from the oral cavity of a patient; s2, obtaining dental pulp stem cells; s3, culturing the dental pulp stem cells under specific conditions; s4, inducing the dental pulp stem cells to differentiate in the direction of osteogenesis, chondrogenesis or periodontal ligament cell formation; s5, transplanting the differentiated dental pulp stem cells to a periodontitis injury area of the patient, and using a biocompatible material; s6, applying a proper local stimulation means around the cell transplantation area; s7, by applying anti-inflammatory drugs locally or systemically, local immune response and inflammatory response are retarded, and repair and regeneration of periodontium are promoted. The problems that an existing treatment method is not lasting in effect, long in recovery period and the like are solved, the damaged periodontium is repaired through the dental pulp stem cells, the treatment effect can be remarkably improved, and the dental pulp stem cells have high clinical application value.

The invention relates to the field of intelligent detection, in particular to a periodontal bone loss positioning and grading system based on a deep learning CT image, and the system comprises the steps: obtaining image data of a periodontal panoramic film and an apical film, carrying out the classified storage, and marking key anatomical points; inputting the preprocessed image data into a deep learning model for training and verification to obtain a periodontal bone loss positioning detection model; and based on the key anatomical points positioned by the periodontal bone loss positioning detection model, calculating a typing evaluation ratio, and based on the typing evaluation ratio, carrying out quantitative typing and site deviation judgment on the periodontal bone loss. According to the method, the key anatomical points can be automatically identified and analyzed from the high-resolution CT slice image, and the diagnosis precision and efficiency are remarkably improved. According to the method, the severity of periodontitis can be quantitatively evaluated, the disease progress can be tracked in real time, and reliable data support is provided for formulating a personalized treatment scheme.

The invention discloses a standardized three-dimensional periodontal attachment quantification system and method, and relates to the technical field of digital oral medicine, and the method comprises the following steps: calibrating a cementum-enamel boundary, dividing a tooth model into a dental crown and a tooth root, and determining the total surface area of the tooth root; performing sensitivity analysis by using the candidate threshold sequence, and determining an optimal diagnosis threshold in combination with a surface integrity criterion; based on the optimal diagnostic threshold, an absolute adhesion area and a relative adhesion area ratio are calculated and output. The invention provides a quantitative method capable of truly, comprehensively and accurately reflecting the three-dimensional pathological change of the periodontal tissue, and the accuracy of a measurement result is ensured through standardized crown root segmentation and accurate geometric judgment; through data-driven parameter optimization, uncertainty caused by manual intervention is eradicated, and objectivity and repeatability of a measurement result are ensured.

The present invention provides a toothpaste composition and a preparation method, a use method and an application thereof, comprising toothpaste and a catalyst; the components of the toothpaste include a hemostatic active ingredient, a peroxide, an auxiliary material and water; the peroxide is hydrogen peroxide or sodium peroxide; the catalyst is a triethanolamine solution, a sodium bicarbonate solution or a catalase. When the present invention is used, after the peroxide contacts the catalyst, oxygen can be quickly released, the blood oxygen saturation is increased, the hypoxic state of the periodontal tissue is alleviated, and the metabolism is promoted. The toothpaste composition of the present invention is easy to use, and only needs to apply the toothpaste and the catalyst on the toothbrush head at the same time to react and release oxygen, and no complex equipment such as high pressure is required, which is convenient for promotion and use. It can help people in plateaus to effectively improve the symptoms of gingival bleeding caused by high-altitude polycythemia and reduce the probability of the occurrence of the symptom.

The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.

The present invention is directed to obtaining a cell population comprising mesenchymal stem cells that are excellent in proliferative capability and osteoblastic differentiation capability and are useful for the regeneration of periodontal tissues. The present invention is also directed to providing a cell sheet and a method for producing a cell sheet, comprising, as a material, a cell population comprising mesenchymal stem cells that are excellent in proliferative capability and osteoblastic differentiation capability and are useful for the regeneration of periodontal tissues. A cell population having alkaline phosphatase activity before calcification induction of 1 U or more is selected and obtained from a cell population comprising mesenchymal stem cells derived from a dental or periodontal tissue. A cell sheet is obtained by the following steps (a) to (c): (a) obtaining a cell population comprising mesenchymal stem cells and having alkaline phosphatase activity; (b) culturing the cell population in a calcification induction medium, and proliferating the cell population on a plastic substrate; and (c) recovering and washing a sheet-shaped cell population formed on the plastic substrate.

To provide an arch wire for orthodontics that can reduce pain and discomfort during orthodontic treatment by using a low-rigidity wire. [Solution] The orthodontic archwire 10 has a loop portion 30 formed in a predetermined shape to enable loop mechanics, and is made of a superelastic material selected from the group consisting of nitinol, titanium-molybdenum alloy (TMA), and gum metal, which have a Young's modulus of 100 GPa or less. When the loop portion is activated, a force that slowly returns to its original shape acts continuously on the target tooth, physiologically promoting tooth movement and reducing pain during treatment, and further reducing the risk of complications due to excessive force, such as root resorption and damage to periodontal tissue.

The utility model relates to the technical field of oral treatment, and discloses ultrasonic tooth orthodontic auxiliary treatment equipment and an oral treatment device, a denture base body is provided with a treatment part which can be selectively attached to gingiva, tooth covering grooves with different sizes can be formed by fitting gum shapes of different patients, the treatment part can be recycled, and the treatment effect is good. The universality of the ultrasonic tooth orthodontic auxiliary treatment equipment is improved, the treatment cost is reduced, the fit degree of the treatment part and the periodontium is higher, and the orthodontic auxiliary treatment effect is stabilized; the flexible circuit board is arranged in the treatment part and deforms together with the treatment part, conductor wiring used for transmitting electric energy is arranged in the flexible circuit board to integrate circuits, additional wiring is not needed, and wiring harness arrangement is neat; the ultrasonic transduction sheets which are in one-to-one correspondence with the teeth to be orthodontic and are arranged opposite to the gingiva are arranged in the treatment part and are electrically connected with the conductor wiring at the same time, assembly is simple, the ultrasonic transduction sheets are conveniently arranged in the oral cavity of a patient, ultrasonic stimulation is carried out on targeted parts of the teeth, and the orthodontic effect is improved.

The invention provides a long-life restoration for oral micro-ecological regulation and an intelligent preparation method and device thereof. The preparation method comprises the following steps: collecting oral micro-ecological medical data of a patient, combining high-precision three-dimensional morphology feature extraction of the restoration, performing multi-modal data deep fusion and feature mining, and utilizing a multi-physics coupling AI design engine to construct a bionic micro-nano texture topological configuration with a specific function; a graded micro-nano composite structure is constructed on the surface of the restoration in situ by adopting an ultrafast laser micro-nano machining system, and the surface wettability is controllably converted from hydrophilic to super-hydrophobic through cooperative regulation and control of the surface wettability, hydrophilicity and hydrophobicity. The prepared prosthesis integrates the functions of passively inhibiting bacteria from being adsorbed on the surface of the prosthesis, preventing gingival atrophy, guiding periodontal tissue regeneration and the like, and the long-life dental prosthesis with the bionic micro-nano texture generated by the AI is obtained. The bionic micro-nano texture manufactured by the invention has excellent mechanical properties and the functions of passive bacteriostasis, damage resistance, gum fixation and the like.

The invention relates to the technical field of oral cavity barrier membrane manufacturing, and particularly provides a periodontal tissue regeneration barrier membrane generation method, device, medium and equipment, and the method can comprise the steps that bone defect three-dimensional data in a periodontal three-dimensional model of a target object is acquired, and the periodontal three-dimensional model comprises tooth data and bone defect area data; generating barrier membrane three-dimensional data covering a bone defect area corresponding to the bone defect three-dimensional data; converting the barrier film three-dimensional data into barrier film plane data; a barrier membrane guide plate corresponding to the barrier membrane plane data is generated, the barrier membrane guide plate is used for manufacturing a barrier membrane, and the barrier membrane covers the bone defect area of the target object. According to some embodiments of the invention, the precise barrier membrane guide plate can be intelligently generated, and digital support is provided for precise medical treatment.

The invention relates to the technical field of auxiliary diagnosis and treatment systems, in particular to an auxiliary diagnosis and treatment system for oral treatment. Comprising an oral cavity data acquisition module, a data preprocessing module, an oral cavity three-dimensional model construction module, an oral cavity tissue health condition quantitative analysis module, an occlusion function evaluation and anomaly recognition module, a preliminary auxiliary diagnosis and treatment scheme making module, an auxiliary diagnosis and treatment scheme simulation module and an auxiliary diagnosis and treatment scheme optimization and adjustment module. According to the method, data such as teeth, periodontium and occlusion relation in the oral cavity of the patient can be comprehensively and accurately obtained through multi-dimensional oral cavity data collection in combination with a data integrity check formula, the problem that in the prior art, the data collection dimension is single and incomplete is solved, and high-quality basic data is provided for subsequent diagnosis and treatment.

The utility model relates to periodontal surgery technical field, especially a kind of periodontal surgery granulation tissue removal instrument set, including, placing tray, the placing tray is provided with the adaptation area that can place six appliances, the placing tray includes the square open-bottom portion with waist line type, and the limiting plate is set in its inner cavity two sides, the rotating handle is movably provided in the length direction both ends of placing tray;Six The appliance is bone defect granulation removal instrument and alveolar crypt granulation removal instrument respectively.The application scheme can effectively help doctor to realize the removal of granulation tissue in clinical process, reduce the influence of residual granulation tissue on periodontal tissue and bone regeneration, reduce the muscle fatigue of doctor, improve the debridement efficiency and regeneration success probability.

The invention discloses an operation space isolation device for oral surgery, relates to the technical field of oral auxiliary instruments, and realizes stable fixation without clamping teeth through deformation clamping fit of an elastic limiting piece and a vertical part, so as to avoid tooth and periodontal injury; the straight sections, oppositely arranged, of the horizontal part are matched with the tongue side and the cheek side of the teeth, the mounting structure is stabilized by combining a cotton roll, tongue interference and saliva invasion are synchronously blocked, and fixing and interference prevention are integrated; fixing, releasing and adjusting are convenient and fast in operation, the overall structure is compact, excessive oral cavity space is not occupied, different tooth forms and clinical scenes are adapted, the diagnosis and treatment efficiency of an operator is improved, the misoperation risk is reduced, and the comfort level and diagnosis and treatment compliance of a patient are improved.

This application provides a method for manufacturing a multi-zone integrated silicone orthodontic appliance, comprising: acquiring three-dimensional data of a user's jaw and constructing a three-dimensional digital model of the appliance based on the three-dimensional data of the user's jaw; obtaining anatomical location data of teeth and orthodontic biomechanical design data, and dividing the target appliance into functional zones with at least two different hardnesses based on the three-dimensional digital model of the appliance, and assigning a zone hardness value to each functional zone; performing mechanical simulation on the three-dimensional digital model of the appliance, analyzing the stress distribution information of each functional zone acting on the teeth and periodontal tissues under the zone hardness value configuration of the virtual appliance constructed by the three-dimensional digital model of the appliance, so as to optimize the three-dimensional digital model of the appliance based on the stress distribution information feedback; converting the manufacturing data output by the optimized stage three-dimensional digital model of the appliance into manufacturing instructions, and driving a printing device to manufacture the corresponding appliance mold or print the corresponding appliance according to the manufacturing instructions.

According to some embodiments of the present invention, a method for performing periodontal measurements from ultrasonic images is provided. After obtaining at least one ultrasonic image of a jaw portion including periodontal tissue of at least one tooth, from the at least one obtained ultrasonic image, a plurality of images are generated, each indicating the presence of at least one anatomical periodontal feature in the at least one obtained ultrasonic image, and the presence of at least one anatomical periodontal feature in the at least one obtained ultrasonic image is confirmed from the corresponding generated images. When the presence of an anatomical periodontal feature in the at least one obtained ultrasonic image required for performing at least one periodontal measurement is confirmed, at least one periodontal measurement is performed from the anatomical periodontal feature whose presence has been confirmed.

The utility model discloses an intraoral saliva suction tube fixator and relates to the field of saliva suction tubes. The intraoral saliva suction tube fixator comprises a supporting frame and fixing seats fixed to the two sides of the supporting frame, saliva suction tube units are inserted into the fixing seats, and connecting tube units are arranged at the ends of the two saliva suction tube units. According to the intraoral saliva suction tube fixator, the suction tubes are arranged on the two sides of the supporting frame body and are matched with the telescopic tubes and the suction openings at the two ends of the supporting frame body to suck saliva on the two sides of the periodontium, the cleanliness and dryness of a treatment area in an oral cavity are further improved, and by pulling the telescopic tubes, the telescopic tubes drive the suction openings to move; the suction port is located at a proper position in the oral cavity, saliva suction is facilitated, the telescopic tube is temporarily fixed to the sixth tooth through the gingival protective agent, the telescopic tube and the suction port are fixed, and then saliva in the oral cavity is sucked.

According to the electrical stimulation device and method for promoting orthodontic tooth movement, the synergistic effect of electrical stimulation parameters and mechanical orthodontic force is intelligently regulated and controlled, and orthodontic is achieved. The built-in microprocessor of the device can monitor the oral cavity state of a patient in real time, and parameters such as current intensity, pulse frequency and pulse width of low-frequency electrical stimulation are dynamically adjusted according to tooth movement data and alveolar bone stress feedback, so that the low-frequency electrical stimulation device accurately meets individual treatment requirements. Meanwhile, the electrical stimulation device is deeply fused with a traditional mechanical orthodontic device, the activity of periodontium cells is activated through electrical stimulation, cell proliferation and differentiation are promoted, the physiological reconstruction process of alveolar bones is accelerated, and a complementary effect with mechanical orthodontic force is formed.

The present disclosure relates to the technical field of medical equipment, and provides a magnetic field adjustable micro-magnetic orthodontic accelerator (10), which forms an orthodontic bridge structure from a buccal plate (11), a lingual plate (12) and a support plate (13), in which a buccal magnet (1) and a lingual magnet (2) are respectively installed on the buccal plate (11) and the lingual plate (12), and the buccal magnet (1) and the lingual magnet (2) form a micro-magnetic field environment around the root of the tooth to be moved during orthodontic treatment, effectively compensate for the loss of physiological magnetic field caused by the pulling of the tooth by the orthodontic accessories, and further promote the metabolism and reconstruction of the periodontal tissue of the tooth to be moved, so as to accelerate the process of orthodontic tooth movement.

The invention discloses an embedded tooth traction device and method, and belongs to the technical field of orthodontic tools. The device comprises a bonding ring, a combined ring and a stress application unit, the bonding ring, the combined ring and the stress application unit are integrally made of orthodontic ligature wires, the bonding ring can be tightly attached according to the radian of the surface of an embedded tooth, the combined ring comprises a plurality of continuous ligature rings and can be adjusted in direction according to a preset track, and the stress application unit adopts TP elastic cotton threads or NITI wires to provide traction force. The traction method comprises the steps of surgical exposure of embedded teeth, sufficient hemostasis, acid etching and bonding, direction adjustment, surgical suture, closed traction, stress application, revival adjustment and the like. The problems that an existing traction accessory is low in sealing degree, prone to falling off, uncontrollable in traction direction, difficult in closed traction suturing and capable of damaging periodontium are solved, the traction accessory has the advantages of being firm in bonding, accurate in traction, minimally invasive, friendly, low in cost and convenient and fast to operate, the traction success rate of the embedded tooth can be effectively increased, and pain of a patient is relieved.

1. Name of the designed product: periodontal probe. 2. Use of the designed product: instrument for examining periodontal tissue. 3. Design points of the designed product: in the color, shape and combination thereof. 4. Picture or photograph best indicating the design points: design 1 perspective view. 5. Design 1 is designated as the basic design. 6. The designed product contains color.

The application discloses a kind of biomimetic mineralization dental cement with antibacterial-mineralization synergistic function and its preparation method and application.The biomimetic mineralization dental cement is constituted by solid phase system and liquid phase system:the solid phase system includes calcium phosphate-based inorganic particles and the antibacterial polysaccharide functional layer in situ constructed on the surface thereof by hydrogen bond and electrostatic interaction;the liquid phase system is ion-regulated solution containing complexing component.Antibacterial polysaccharide is induced to participate in mineral phase growth in solidification process by pre-composite process, and forms biological mineralization composite structure, so as to realize antibacterial and mineralization functions simultaneously.The material is in the form of injectable paste, and the solidification time can be adjusted within 5-240 min, the compressive strength after solidification reaches 5-30 MPa, and it has good X-ray resistance, biocompatibility and broad-spectrum antibacterial performance.The biomimetic mineralization dental cement of the application is suitable for dental root canal filling, tooth remineralization repair and periodontal tissue repair and other fields.

The invention discloses an electrostatic spinning nanofiber membrane for promoting jawbone defect osteogenesis and a preparation method, relates to the technical field of medical tissue engineering materials, and aims to solve the problem that a tissue engineering scaffold applied to periodontal tissue regeneration is mostly soaked in a solution, and the physical loading mode is not beneficial to long-term stable release of growth factors. In the prior art, metal ions are often used for activating osteoblasts, but the activation effect is limited, so that the metal ions are difficult to promote the regeneration of periodontal tissues because the metal ions are difficult to fully mobilize the initiative of the cells. The invention provides an electrostatic spinning nanofiber membrane for promoting jaw defect osteogenesis and a preparation method thereof. The preparation method comprises the following steps: preparing freeze-dried CGF powder; preparing a PVA / SA / nHA solution, and adding the freeze-dried CGF powder to obtain a spinning solution; and collecting the spinning solution on an aluminum foil roller to obtain the PVA / SA / CGF / nHA electrostatic spinning nanofiber membrane. Concentrated growth factors can be continuously and stably released, and osteogenic differentiation of peripheral jawbones is promoted.