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37 results about "Periodontium" patented technology

The periodontium is the specialized tissues that both surround and support the teeth, maintaining them in the maxillary and mandibular bones. The word comes from the Greek terms περί peri-, meaning "around" and -odont, meaning "tooth". Literally taken, it means that which is "around the tooth". Periodontics is the dental specialty that relates specifically to the care and maintenance of these tissues. It provides the support necessary to maintain teeth in function. It consists of four principal components, namely...

Dynamic simulation method and system for tooth movement process based on Type model

The invention relates to a dynamic simulation method and system for a tooth movement process based on a Type model, and the method comprises the steps: carrying out the data collection of an artificial tooth and a fixed appliance through three-dimensional scanning, and obtaining the three-dimensional data of a tooth jaw structure; performing overlap analysis on the crown root model according to the three-dimensional data to obtain a digital dental model containing periodontal tissues; performing material attribute assignment on an anatomical structure in the digital tooth jaw model according to preset material parameters to obtain a biomechanical tooth jaw model; and performing time recursion iteration on the biomechanical tooth jaw model through finite element analysis to obtain four-dimensional dynamic simulation data for simulating a tooth movement process, so as to provide visual orthodontic process teaching demonstration based on the four-dimensional dynamic simulation data. According to the invention, the dynamic visual simulation of the tooth movement process is realized, the feedback of the Type Dont system can be quantified, and the teaching interactivity is improved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

A tooth-fixing pain-relieving and inflammation-clearing traditional Chinese medicine composition

PendingCN122424247ATissue repairBurning Pain
The application discloses a kind of solid teeth pain-relieving and inflammation-clearing traditional Chinese medicine composition, it is related to traditional Chinese medicine product technical field.The composition is composed of gypsum, raw rehmannia, coptis, talc, ocher, radix cyathulae and salvia miltiorrhiza seven raw medicinal materials, wherein gypsum, raw rehmannia are monarch drug, clear and purge stomach fire, cool blood and nourish yin;Coptis, talc are ministerial drug, clear heat and dry dampness, lead heat down;Ocher, radix cyathulae are auxiliary drug, heavy town counteract, lead fire down;Salvia miltiorrhiza is servant drug, promote blood circulation and remove blood stasis, promote tissue repair.Modern pharmacological research shows that each drug of the present party has the effects of anti-inflammatory, analgesic, antibacterial, improving microcirculation and protecting periodontal tissue etc.Clinical observation shows that the pain of most patients caused by stomach fire attacking upward, gum redness and swelling, burning pain, bleeding is significantly reduced after taking 1-2 doses, redness and swelling gradually subside.Compared with existing Chinese patent medicines, the present application is simple in prescription, low in cost, has the dual effects of rapid pain relief and long-term tooth fixation, and is especially suitable for patients with recurrent toothache and early periodontitis.
Owner:周桂芳 +1

Ultrasonic tooth orthodontic auxiliary treatment equipment and oral treatment device

ActiveCN223987933UUltrasound therapyOthrodonticsPeriodontiumOral treatment
The utility model relates to the technical field of oral treatment, and discloses ultrasonic tooth orthodontic auxiliary treatment equipment and an oral treatment device, a denture base body is provided with a treatment part which can be selectively attached to gingiva, tooth covering grooves with different sizes can be formed by fitting gum shapes of different patients, the treatment part can be recycled, and the treatment effect is good. The universality of the ultrasonic tooth orthodontic auxiliary treatment equipment is improved, the treatment cost is reduced, the fit degree of the treatment part and the periodontium is higher, and the orthodontic auxiliary treatment effect is stabilized; the flexible circuit board is arranged in the treatment part and deforms together with the treatment part, conductor wiring used for transmitting electric energy is arranged in the flexible circuit board to integrate circuits, additional wiring is not needed, and wiring harness arrangement is neat; the ultrasonic transduction sheets which are in one-to-one correspondence with the teeth to be orthodontic and are arranged opposite to the gingiva are arranged in the treatment part and are electrically connected with the conductor wiring at the same time, assembly is simple, the ultrasonic transduction sheets are conveniently arranged in the oral cavity of a patient, ultrasonic stimulation is carried out on targeted parts of the teeth, and the orthodontic effect is improved.
Owner:SHANGHAI ZHANBO TECH CO LTD

Auxiliary diagnosis and treatment system for oral treatment

The invention relates to the technical field of auxiliary diagnosis and treatment systems, in particular to an auxiliary diagnosis and treatment system for oral treatment. Comprising an oral cavity data acquisition module, a data preprocessing module, an oral cavity three-dimensional model construction module, an oral cavity tissue health condition quantitative analysis module, an occlusion function evaluation and anomaly recognition module, a preliminary auxiliary diagnosis and treatment scheme making module, an auxiliary diagnosis and treatment scheme simulation module and an auxiliary diagnosis and treatment scheme optimization and adjustment module. According to the method, data such as teeth, periodontium and occlusion relation in the oral cavity of the patient can be comprehensively and accurately obtained through multi-dimensional oral cavity data collection in combination with a data integrity check formula, the problem that in the prior art, the data collection dimension is single and incomplete is solved, and high-quality basic data is provided for subsequent diagnosis and treatment.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY +1

A kit of periodontal surgery granulation tissue removal instruments

ActiveCN224461827UPeriodontiumPeriodontal surgery
The utility model relates to periodontal surgery technical field, especially a kind of periodontal surgery granulation tissue removal instrument set, including, placing tray, the placing tray is provided with the adaptation area that can place six appliances, the placing tray includes the square open-bottom portion with waist line type, and the limiting plate is set in its inner cavity two sides, the rotating handle is movably provided in the length direction both ends of placing tray;Six The appliance is bone defect granulation removal instrument and alveolar crypt granulation removal instrument respectively.The application scheme can effectively help doctor to realize the removal of granulation tissue in clinical process, reduce the influence of residual granulation tissue on periodontal tissue and bone regeneration, reduce the muscle fatigue of doctor, improve the debridement efficiency and regeneration success probability.
Owner:CHANGSHA TIANTIAN DENTAL EQUIP CO LTD

Operating space isolation device for oral surgery

PendingCN121549954ADentistryPeriodontiumStable fixation
The invention discloses an operation space isolation device for oral surgery, relates to the technical field of oral auxiliary instruments, and realizes stable fixation without clamping teeth through deformation clamping fit of an elastic limiting piece and a vertical part, so as to avoid tooth and periodontal injury; the straight sections, oppositely arranged, of the horizontal part are matched with the tongue side and the cheek side of the teeth, the mounting structure is stabilized by combining a cotton roll, tongue interference and saliva invasion are synchronously blocked, and fixing and interference prevention are integrated; fixing, releasing and adjusting are convenient and fast in operation, the overall structure is compact, excessive oral cavity space is not occupied, different tooth forms and clinical scenes are adapted, the diagnosis and treatment efficiency of an operator is improved, the misoperation risk is reduced, and the comfort level and diagnosis and treatment compliance of a patient are improved.
Owner:THE SECOND HOSPITAL OF HEBEI MEDICAL UNIV

A method, apparatus and appliance for manufacturing a multi-zone integrated silicone orthodontic appliance

This application provides a method for manufacturing a multi-zone integrated silicone orthodontic appliance, comprising: acquiring three-dimensional data of a user's jaw and constructing a three-dimensional digital model of the appliance based on the three-dimensional data of the user's jaw; obtaining anatomical location data of teeth and orthodontic biomechanical design data, and dividing the target appliance into functional zones with at least two different hardnesses based on the three-dimensional digital model of the appliance, and assigning a zone hardness value to each functional zone; performing mechanical simulation on the three-dimensional digital model of the appliance, analyzing the stress distribution information of each functional zone acting on the teeth and periodontal tissues under the zone hardness value configuration of the virtual appliance constructed by the three-dimensional digital model of the appliance, so as to optimize the three-dimensional digital model of the appliance based on the stress distribution information feedback; converting the manufacturing data output by the optimized stage three-dimensional digital model of the appliance into manufacturing instructions, and driving a printing device to manufacture the corresponding appliance mold or print the corresponding appliance according to the manufacturing instructions.
Owner:BJ APPLIANCE HEALTH SCI & TECH CO LTD

Intraoral saliva suction tube fixer

ActiveCN224023715USurgerySomatoscopePeriodontiumRetainer
The utility model discloses an intraoral saliva suction tube fixator and relates to the field of saliva suction tubes. The intraoral saliva suction tube fixator comprises a supporting frame and fixing seats fixed to the two sides of the supporting frame, saliva suction tube units are inserted into the fixing seats, and connecting tube units are arranged at the ends of the two saliva suction tube units. According to the intraoral saliva suction tube fixator, the suction tubes are arranged on the two sides of the supporting frame body and are matched with the telescopic tubes and the suction openings at the two ends of the supporting frame body to suck saliva on the two sides of the periodontium, the cleanliness and dryness of a treatment area in an oral cavity are further improved, and by pulling the telescopic tubes, the telescopic tubes drive the suction openings to move; the suction port is located at a proper position in the oral cavity, saliva suction is facilitated, the telescopic tube is temporarily fixed to the sixth tooth through the gingival protective agent, the telescopic tube and the suction port are fixed, and then saliva in the oral cavity is sucked.
Owner:TAIYUAN HENGLUN YUELUN DENTAL HOSPITAL CO LTD

Implanted tooth traction device and method

PendingCN122031114AArch wiresBracketsPeriodontiumAcid erosion
The invention discloses an embedded tooth traction device and method, and belongs to the technical field of orthodontic tools. The device comprises a bonding ring, a combined ring and a stress application unit, the bonding ring, the combined ring and the stress application unit are integrally made of orthodontic ligature wires, the bonding ring can be tightly attached according to the radian of the surface of an embedded tooth, the combined ring comprises a plurality of continuous ligature rings and can be adjusted in direction according to a preset track, and the stress application unit adopts TP elastic cotton threads or NITI wires to provide traction force. The traction method comprises the steps of surgical exposure of embedded teeth, sufficient hemostasis, acid etching and bonding, direction adjustment, surgical suture, closed traction, stress application, revival adjustment and the like. The problems that an existing traction accessory is low in sealing degree, prone to falling off, uncontrollable in traction direction, difficult in closed traction suturing and capable of damaging periodontium are solved, the traction accessory has the advantages of being firm in bonding, accurate in traction, minimally invasive, friendly, low in cost and convenient and fast to operate, the traction success rate of the embedded tooth can be effectively increased, and pain of a patient is relieved.
Owner:GUANGZHOU DELUN DENTAL CLINIC CO LTD

Periodontal probe

ActiveCN309971354SPeriodontiumBiomedical engineering
1. Name of the designed product: periodontal probe. 2. Use of the designed product: instrument for examining periodontal tissue. 3. Design points of the designed product: in the color, shape and combination thereof. 4. Picture or photograph best indicating the design points: design 1 perspective view. 5. Design 1 is designated as the basic design. 6. The designed product contains color.
Owner:METROPARK MEDICAL TECH (GUANGZHOU) CO LTD

A biomimetic mineralized dental cement with antibacterial-mineralization synergistic function and a preparation method and application thereof

ActiveCN121489794BImpression capsDentistry preparationsTooth RemineralizationBiocompatibility
The application discloses a kind of biomimetic mineralization dental cement with antibacterial-mineralization synergistic function and its preparation method and application.The biomimetic mineralization dental cement is constituted by solid phase system and liquid phase system:the solid phase system includes calcium phosphate-based inorganic particles and the antibacterial polysaccharide functional layer in situ constructed on the surface thereof by hydrogen bond and electrostatic interaction;the liquid phase system is ion-regulated solution containing complexing component.Antibacterial polysaccharide is induced to participate in mineral phase growth in solidification process by pre-composite process, and forms biological mineralization composite structure, so as to realize antibacterial and mineralization functions simultaneously.The material is in the form of injectable paste, and the solidification time can be adjusted within 5-240 min, the compressive strength after solidification reaches 5-30 MPa, and it has good X-ray resistance, biocompatibility and broad-spectrum antibacterial performance.The biomimetic mineralization dental cement of the application is suitable for dental root canal filling, tooth remineralization repair and periodontal tissue repair and other fields.
Owner:SUZHOU UNIV

Orthodontic device and orthodontic method based on self-adaptive orthodontic force of memory alloy

PendingCN121445510AArch wiresBracketsPeriodontiumShape-memory alloy
The invention provides an orthodontic device and orthodontic method based on self-adaptive orthodontic force of memory alloy, and relates to the technical field of tooth orthodonties.The orthodontic method comprises the following steps that Sp1, the dental form, periodontal tissue response curve and orthodontic force requirement of a patient are evaluated through digital scanning and biomechanics, a personalized dentition model is generated, and an evaluation result is formed; sp2, designing and preparing a memory alloy device according to an evaluation result of Sp1, setting a multi-phase-change temperature gradient, and performing surface ion implantation to optimize biocompatibility. According to the self-adaptive orthodontic force orthodontic method based on the memory alloy in the scheme, through innovative design and application of intelligent materials, the self-adaptive orthodontic force is obtained; multiple key problems in the existing orthodontic technology are effectively solved, and the accuracy, comfort and reliability of treatment are remarkably improved.
Owner:SHANGHAI DONGHUI STOMATOLOGICAL HOSPITAL CO LTD

Periodontal brace for Uyghur medicine treatment of periodontitis

PendingCN121265302ADentistryTopical treatmentTopical drug
The invention discloses a periodontal brace for treating periodontitis in Uyghur medicine, and relates to the technical field of auxiliary devices for dental treatment. The tooth socket comprises a customized half-soft membrane tooth socket body, and a medicine storage groove is formed in the inner side of the tooth socket body corresponding to the periphery of gingiva and used for containing Uyghur medicine ointment. The tooth socket is ensured to be fit with the shape of the oral cavity through mold taking customization, the medicine storage groove can prolong the contact time of medicine and periodontium, the medicine storage groove is matched with pure natural Uyghur medicine to avoid the side effect of chemical medicine, and the tooth socket can be repeatedly used. The problems that an existing local treatment medicine is short in treatment effect and obvious in side effect are solved, the treatment effect and safety of chronic periodontitis are improved, and the traditional Chinese medicine composition is suitable for clinical periodontitis local medicine treatment scenes.
Owner:XINJIANG UYGUR MEDICAL HOSPITAL (XINJIANG UYGUR AUTONOMOUS REGION SECOND PEOPLES HOSPITAL)

Method, system, and computer program for performing periodontal measurements from ultrasound images

According to some embodiments of the invention, it is provided a method for carrying out periodontal measurements from ultrasound images. After obtaining at least one ultrasound image of a jaw portion comprising at least one tooth periodontium, a plurality of images are generated from the at least one obtained ultrasound image, each of the generated images representing a presence of at least one anatomical periodontal feature in the at least one obtained ultrasound image, and the presence of at least one anatomical periodontal feature in the at least one obtained ultrasound image is validated from the corresponding generated image. If the presence of anatomical periodontal features requested for carrying out at least one periodontal measurement, in the at least one obtained ultrasound image, is validated, the at least one periodontal measurement is carried out from anatomical periodontal features which presence is validated.
Owner:CARESTREAM DENTAL LLC +1

A system and device for evaluating periodontal tissue inflammation

PendingCN122297156AImprove complianceConfidencePeriodontiumDisease
This invention relates to a system and apparatus for evaluating periodontal tissue inflammation. The system includes: an attachment loss surface area calculation module for calculating the attachment loss surface area based on clinical attachment loss measurements; a recession surface area calculation module for calculating the gingival recession surface area based on gingival recession measurements; a periodontal epithelial surface area calculation module for subtracting the gingival recession surface area from the attachment loss surface area to obtain the periodontal epithelial surface area; a periodontal inflammation surface area calculation module for multiplying the periodontal epithelial surface area by the proportion of sites affected by probing bleeding to obtain the periodontal inflammation surface area; and a periodontal tissue inflammation evaluation module for calculating the sum of the periodontal inflammation surface areas of all teeth. This invention fully quantifies and objectively reflects the periodontal inflammation and periodontal tissue damage, defining the degree of inflammation in periodontitis as a new continuous variable, which can more accurately describe the degree of inflammation and minimize the subjectivity in assessing the severity of the disease.
Owner:HOSPITAL OF STOMATOLOGY CHINA MEDICAL UNIV

Compositions and delivery methods for treating dental infections, inflammation, sensitivity, and for use in dental restorations

ActiveUS12714837B2PeriodontiumDisease
The present invention provides a method of treating a condition affecting a tooth or periodontium in a subject, comprising administering to the subject's tooth or periodontium a composition comprising biocompatible magnetic, magnetizable, or magnetically responsive agents; and applying an external magnetic field, wherein the magnetic, magnetizable, or magnetically responsive agents migrate to a desired location in response to the externally applied magnetic field, thereby treating a condition affecting the tooth or periodontium in the subject.
Owner:UNIV OF MARYLAND

Antibacterial and anti-mineralization material for softening dental calculus and inhibiting formation of dental calculus

The invention provides an antibacterial and anti-mineralization material for softening dental calculus and inhibiting formation of dental calculus, a preparation method of the antibacterial and anti-mineralization material comprises the following steps: dissolving chitosan and / or carboxymethyl chitosan and 1-hydroxybenzotriazole in deionized water under a stirring condition to obtain a solution A; under the stirring condition, an organic additive solution and a 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride solution are dropwise added into the solution A obtained in the step 1), and a solution B is obtained; performing low-temperature dialysis on the solution B obtained in the step 2), and performing freeze drying to obtain a product C; under the stirring condition, adding the product C and lysozyme into deionized water, and reacting to obtain the antibacterial and anti-mineralization material for softening dental calculus and inhibiting formation of dental calculus. The material disclosed by the invention can be combined with the surface of residual dental calculus after periodontal basic treatment, surface plaque biofilm is removed, and rapid mineralization of the material is inhibited by combining calcium ions, cell colonization is promoted, and periodontal tissue recovery is promoted.
Owner:XIAN MANTES BIOTECHNOLOGY CO LTD

Periodontal targeted near-infrared light dual-jaw therapeutic instrument capable of protecting dental crown

PendingCN122251792AImprove mobile efficiencyImprove orthodontic acceleration efficiencyBracketsLight therapyLaser lightPeriodontal Membrane
This invention belongs to the field of orthodontic instrument technology, specifically a periodontal targeted near-infrared light bimaxillary therapy device that protects tooth crowns. It includes a protective brace and a bimaxillary irradiation device. The protective brace includes a maxillary protective brace and a mandibular protective brace, each comprising a lingual plate and a labial plate. The labial plate includes a cervical sleeve and a receiving groove. The bimaxillary irradiation device includes an outer irradiation plate, an inner irradiation plate, and a flexible occlusal plate. Near-infrared laser lamps are installed on the outer and inner irradiation plates. This invention achieves simultaneous irradiation of the labial and lingual periodontal tissues of both jaws, significantly improving orthodontic efficiency. It can simultaneously irradiate the entire periodontal area of ​​both jaws in a single treatment, eliminating the need for separate upper and lower jaw procedures, shortening treatment time, achieving simultaneous activation of all periodontal tissues, and improving tooth movement efficiency. The bimaxillary irradiation device uses precise lamp placement according to the periodontal ligament area, working in conjunction with the protective brace to fully cover the protective crown, synergistically avoiding thermal and light damage.
Owner:SICHUAN UNIV

Gingival tissue hemodynamic spectroscopic index construction system based on near-infrared spectroscopy

The application discloses a kind of gingival tissue hemodynamics spectral index construction systems based on near infrared spectroscopy, it is characterized in that, including visible near infrared spectrometer and data processing unit;Wherein, the visible near infrared spectrometer is used to collect the spectral data of each target site around the tooth to be detected;The data processing unit is used to normalize the spectral curve in each spectral data collected to consistent measurement background, determine the spectral absorption characteristics of gingival tissue oxyhemoglobin and deoxyhemoglobin is extracted;Then based on the spectral absorption characteristics obtained, gingival tissue hemodynamics index is calculated.The gingival tissue hemodynamics spectral index obtained based on the application can assist in quickly, accurately, non-invasively and cost-effectively completing periodontal tissue inflammation detection, and provides accurate and effective assistance for the clinical diagnosis of periodontitis.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY

A dynamic simulation method and system for tooth movement process based on a typodont model

The application relates to a dynamic simulation method and system for tooth movement based on a Typodont model, which comprises the following steps: collecting data of artificial teeth and fixed appliances through three-dimensional scanning to obtain three-dimensional data of a dental arch structure; performing superposition analysis on a crown-root model according to the three-dimensional data to obtain a digital dental arch model containing periodontal tissue; assigning material attributes to anatomical structures in the digital dental arch model according to preset material parameters to obtain a biomechanical dental arch model; performing time recursion iteration on the biomechanical dental arch model through finite element analysis to obtain four-dimensional dynamic simulation data simulating a tooth movement process, and providing visual orthodontic process teaching demonstration based on the four-dimensional dynamic simulation data. The application realizes dynamic visual simulation of the tooth movement process, can quantize feedback of the Typodont system, and improves teaching interactivity.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

Novel periodontal flap operation matching instrument

PendingCN121622304AEndoscopesDental toolsPeriodontiumApparatus instruments
The invention relates to the technical field of medical instruments, in particular to a novel periodontal flap operation matching instrument which comprises a holding cylinder, one end of the holding cylinder is rotationally matched with a rotating cylinder, and cleaning liquid used for cleaning the oral cavity is stored in the rotating cylinder; one end, far away from the holding cylinder, of the rotating cylinder is fixedly connected with a flap cutter; a plurality of cleaning holes used for spraying cleaning liquid are formed in the side wall of the flap turning cutter, and the cleaning holes are all communicated with the rotating cylinder; a plurality of suction holes for sucking waste liquid are formed in one end, far away from the rotating cylinder, of the flap turning knife; a conveying assembly used for driving the rotating cylinder to convey cleaning liquid to the cleaning holes and a suction assembly used for driving the suction holes to suck waste liquid are arranged in the holding cylinder. An angle adjusting assembly used for adjusting the angle of the flap turning knife is further arranged in the holding cylinder. Through the design of the rotating cylinder and the flap turning knife, the periodontium of a patient is cleaned and drained synchronously while the gingiva of the patient is treated, a doctor does not need to replace surgical instruments, the continuity of the operation is effectively guaranteed, and the operation efficiency is improved.
Owner:THE FIRST MEDICAL CENT CHINESE PLA GENERAL HOSPITAL

Dental preparation comprising fibers based on hyaluronic acid with regulated biodegradability

A biodegradable dental preparation comprising at least one water-soluble fiber from hyaluronic acid or a physiologically acceptable salt thereof and at least one fiber from a non-polar derivative of hyaluronic acid is disclosed. The dental preparation may comprise an antimicrobial agent. The dental preparation may be useful in the treatment of periodontal disease or in the treatment of injuries in the periodontium and oral mucosa. Methods of preparing the dental preparations, fibers thereof, and related compositions thereto, are also disclosed.
Owner:CONTIPRO AS

Application of recombinant human glaze matrix protein in anti-periodontitis oral care product

PendingCN122075334ACosmetic preparationsAntibacterial agentsPeriodontal pathogenToothpaste
The invention discloses application of recombinant human glaze matrix protein in preparation of an anti-periodontitis oral care product. The oral care product is prepared from rhEMPs, glycerin, sorbitol, poloxamer 188, sodium lauroyl sarcosinate, potassium nitrate, sucralose, xylitol, methylparaben, propylene glycol, PEG-40 hydrogenated castor oil, domiphen and water. The core innovation of the oral care product is that the stability bottleneck of rhEMPs in the physiological pH environment of the oral care product is solved by utilizing the synergistic stabilization effect of poloxamer 188 and sodium lauroyl sarcosinate, and it is found that when the oral care product is combined with components such as potassium nitrate, periodontal pathogenic bacteria can be remarkably inhibited, gingival inflammation can be relieved, and periodontal tissue repair can be promoted. The product form can be mouth wash, oral spray or toothpaste, the preparation process is simple, the stability is good, and a brand new solution is provided for daily adjuvant therapy of periodontitis.
Owner:GUANGZHOU XUELIANG BIOTECHNOLOGY DEVELOPING CO LTD

Streptococcus salivarius CCFM1399 and postbiotic for alleviating bone resorption and periodontal tissue damage

The application discloses a Streptococcus salivarius CCFM1399 and its postbiotic for relieving bone resorption and periodontal tissue damage, and belongs to the technical field of microorganisms. The Streptococcus salivarius CCFM1399 provided by the application is separated from oral plaque of healthy teenagers, has the effects of relieving bone resorption and resisting inflammation, and specifically has the following effects: improving the expression of osteoprotegerin (OPG) protein level and gene level of MC3T3-E1 cells in vitro; reducing the alveolar bone resorption amount of orthodontic bone resorption rats, reducing the number of osteoclasts in alveolar bone, and improving the OPG level in serum of rats; reducing the secretion of inflammatory factors IL-6, TNF-alpha and MPO of orthodontic bone resorption rats; and improving the pathological condition of alveolar bone tissue of orthodontic bone resorption rats. Therefore, the Streptococcus salivarius has great application prospect in products for relieving bone resorption and assisting in inhibiting periodontal tissue inflammation.
Owner:JIANGNAN UNIV

Composition for preventing, alleviating or treating periodontitis, containing potentilla chinensis extract or apigenin-7-o-beta-glucuronide as active ingredient

PCT designated stageWO2026079844A1Organic active ingredientsCosmetic preparationsApigetrinUronic acid
Disclosed in the present invention is a composition for preventing, alleviating or treating periodontitis, the composition containing, as an active ingredient, a potentilla chinensis extract, apigenin-7-O-β-glucuronide, or a sitologically acceptable salt thereof. The present invention inhibits the mRNA expression of COX-2, IL-6, and MMP-3 and reduces the CEJ-ABC distance, thus suppressing inflammation, protecting the periodontium, and mitigating bone loss. Therefore, the present invention has the effects of preventing, alleviating or treating periodontitis.
Owner:BELABELBIO INC

Preparation method of injectable antioxidant mechanical buffer porous hydrogel microsphere delivery odontogenic stem cell system and application of injectable antioxidant mechanical buffer porous hydrogel microsphere delivery odontogenic stem cell system in periodontal tissue regeneration

The invention belongs to the field of biomedical materials and periodontal tissue engineering, and relates to an injectable anti-oxidation mechanical buffer porous hydrogel microsphere delivery odontogenic stem cell system as well as a preparation method and application of the injectable anti-oxidation mechanical buffer porous hydrogel microsphere delivery odontogenic stem cell system. The microsphere is constructed by adopting a dynamic bond-covalent bond dual-network structure, has injectability, stress relaxation and mechanical support properties, and introduces a polyphenol functional group to remove active oxygen and regulate and control an inflammatory microenvironment. The communicated porous microspheres with controllable particle sizes are obtained through emulsification balling and freezing pore-forming processes and are used for loading the odontogenic stem cells to form a regeneration delivery system. The system can improve the dryness and osteogenic differentiation capacity of the odontogenic stem cells, reduce oxidative stress and inflammatory response, promote alveolar bone defect repair and bone mass recovery under the conditions of inflammation and orthodontic pressure stress, and has good biocompatibility and application prospects.
Owner:THE AFFILIATED HOSPITAL OF QINGDAO UNIV +1

periodontal probe (furcation probe)

ActiveCN309971353SPeriodontiumBiomedical engineering
1. The name of the design product: periodontal probe (furcation probe). 2. The use of the design product: an instrument for examining periodontal tissue. 3. The design points of the design product: in the color, shape and combination thereof. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 is designated as the basic design. 6. The design for which protection is sought contains color.
Owner:METROPARK MEDICAL TECH (GUANGZHOU) CO LTD

BPDAH / VMA hydrogel sustained-release microsphere for promoting periodontal bone regeneration as well as preparation method and application of BPDAH / VMA hydrogel sustained-release microsphere

The invention discloses BPDAH / VMA hydrogel sustained-release microspheres for promoting periodontal bone regeneration as well as a preparation method and application of the BPDAH / VMA hydrogel sustained-release microspheres, and provides a new material selection for clinical treatment of periodontal bone regeneration, so that the BPDAH / VMA hydrogel sustained-release microspheres can continuously and efficiently promote periodontal bone tissue regeneration, regulate and control an osteogenesis microenvironment and reduce postoperative complications such as infection. The method is expected to become a preferable scheme widely applied to clinical treatment materials, has good clinical application potential, and is expected to provide a new direction for design of other periodontal tissue regeneration and bone regeneration repair materials. VMA is innovatively grafted on the surfaces of the GelMA hydrogel microspheres, and B (at) PH NPs are adsorbed and loaded, so that the GelMA hydrogel microspheres have the curative effects of regulating an osteogenesis microenvironment and inducing periodontal osteoblast differentiation. According to the invention, the hydrogel microsphere is directly injected into the periodontal pocket near the periodontal bone tissue defect, and the osteogenesis microenvironment can be regulated and controlled and osteoblast differentiation can be induced through the slow release effect of the hydrogel microsphere on loaded osteogenesis and anti-inflammatory components, so that periodontal bone regeneration is promoted.
Owner:CENT SOUTH UNIV +2

Periodontal targeted near-infrared light dual-jaw therapeutic instrument capable of protecting dental crown

ActiveCN122251792BLaser lightPeriodontal Membrane
The application belongs to the technical field of oral orthodontic instruments, and particularly relates to a periodontal-targeting near-infrared light double-jaw therapeutic instrument capable of protecting tooth crowns, which comprises a protective tooth cover and a double-jaw irradiation instrument. The protective tooth cover comprises a maxillary protective tooth cover and a mandibular protective tooth cover, and each of the maxillary protective tooth cover and the mandibular protective tooth cover comprises a lingual side plate and a labial side plate. The labial side plate comprises a tooth neck cover and a containing groove. The double-jaw irradiation instrument comprises an outer irradiation plate, an inner irradiation plate and a flexible occlusion plate, and near-infrared laser lamps are arranged on the outer irradiation plate and the inner irradiation plate. The application realizes synchronous irradiation of double-jaw labial and lingual periodontal tissues, and significantly improves orthodontic acceleration efficiency. The application can simultaneously irradiate the whole periodontal region of the double-jaw labial and lingual sides in one wearing process, and does not need to operate the maxilla and the mandible in turns, thereby shortening the treatment time, realizing synchronous activation of the whole periodontal tissue and improving tooth movement efficiency. The double-jaw irradiation instrument is precisely arranged according to the periodontal membrane area, and cooperates with the protective tooth cover to fully wrap and protect the tooth crowns, thereby avoiding heat damage and light damage.
Owner:SICHUAN UNIV

Pharmaceutical composition for preventing or treating a periodontal disease or dislocated traumatic tooth

PendingUS20260136597A1DiseaseBone sialoprotein
Methods for preventing or treating periodontal disease or a dislocated traumatic tooth, for for regenerating periodontium, and for promoting expression of any one or more genes of bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), cementum attachment protein (CAP), collagen type III (COL3), and periostin, are disclosed. The methods include administering an effective amount of a peptide comprising the amino acid sequence of SEQ ID NO: 29 or a pharmaceutically acceptable salt thereof or a composition containing the peptide of a salt thereof.
Owner:HYSENSBIO CO LTD