106 results about "Ultrasonic stimulation" patented technology

The invention discloses a transcranial ultrasonic brain regulating and controlling method and device. According to the transcranial ultrasonic brain regulating and controlling method, short-pulse ultrasounds generated by a focused ultrasonic transducer pass through an ultrasonic coupling medium and then are transmitted to the head of a sample, and then nervous physiological change is caused by the mechanical effect; a focused ultrasonic detector is driven by a three-dimensional electric scanning platform to achieve scanning and then ultrasonic stimulation is carried out on different parts of the head. The transcranial ultrasonic brain regulating and controlling device comprises a water tank filled with the ultrasonic coupling medium, the focused ultrasonic transducer, a power amplifier, a signal generator, the three-dimensional electric scanning platform, a driving motor, a computer provided with motor control software, a connecting rod and a plastic film, wherein the focused ultrasonic transducer, the power amplifier and a function generator are electrically connected in sequence, the three-dimensional electric scanning platform, the driving motor, and the computer provided with the motor control software are electrically connected in sequence, and the focused ultrasonic transducer is connected with the three-dimensional electric scanning platform through the connecting rod. The transcranial ultrasonic brain regulating and controlling method and device have the advantage of being capable of achieving multidirectional transcranial ultrasonic brain regulation and control.

An electronic system for determining the density and structure of bone tissue and stimulating osteogenesis in dentistry, having a diagnosis system for injecting an ultrasonic signal U(t) into a bone portion and analyzing the ultrasonic signal received after traveling through the bone portion to determine a number of characteristic data items of the signal describing physical and structural characteristics of the bone tissue. The diagnosis system performs a number of measuring steps to determine and memorize a set of characteristic data items describing progress of a bone growth process and/or a bone repair process following extraction of a tooth and/or placement of a dental prosthesis in the bone portion. The system also has an osteogenesis stimulation system for directing an ultrasonic stimulation sign al onto the bone portion to promote the bone growth and/or bone repair process.

The invention discloses a system for transcranial ultrasonic stimulation of mouse and synchronous acquisition of electroencephalogram and electromyogram signals and relates to the field of transcranial ultrasonic stimulation research and synchronous signal acquisition. The system comprises a transcranial ultrasonic stimulation module, a pulse transcranial ultrasonic signal generation module, a brain myoelectric signal acquisition and processing module and a power supply. The device has a series of advantages of stable signal acquisition, strong expansion storage capacity, portability, small size, easiness in operation and the like, and can be effectively applied to real-time synchronous acquisition of electroencephalogram and electromyogram signals of conscious and freely movable mice in transcranial ultrasonic stimulation experiments of various samples. Moreover, the storage module is expanded, and the problems of overlarge storage amount of long-time use data, distortion of wirelesstransmission data and the like are avoided. The system is convenient for subsequent off-line processing of brain myoelectric signals stimulated by transcranial ultrasound, and provides technical support for future mechanism research of transcranial ultrasound stimulation and clinical application of neuromodulation technology.

The invention provides a system for synchronizing transcranial ultrasonic stimulation and electroencephalography recording of the human body, which comprises a computer (110) containing control software, a signal generator (130), a radio frequency amplifier (140), an ultrasonic transducer (150), a synchronization control module (120), a transducer-scalp coupling module (151), an electroencephalography system (160) and a signal receiving terminal (161), and is characterized in that real-time communication between the signal generator (130) and the electroencephalography system (160) can be realized by using the synchronization control module (120), and complete synchronization of ultrasonic stimulation and electroencephalographic signal collection is realized. The system provided by the invention for synchronizing transcranial ultrasonic stimulation and electroencephalography recording of the human body can be applied to basic brain cognitive function research and clinical brain disease intervention treatment research, can realize synchronization of ultrasonic stimulation and electroencephalographic signal recording and solves the technical problems of multi-channel synchronous or asynchronous independent ultrasonic stimulation and corresponding electroencephalographic signal synchronous recording and stimulation marking.

A fuel injector intended for use on an internal combustion engine contains an injector needle that is longitudinally driven by an ultrasonic actuator during the time the injector valve is open to provide an atomized fuel spray output of sub-micron droplet sizes. A piezoelectric disk stack is mounted within the injector housing to surround a portion of the injector needle component and is used to provide the mechanical ultrasonic stimulation to the injector valve at the end of the injector needle and set up a corresponding wave-front at the injector valve to atomize the fuel as it leaves the injector nozzle.

The invention relates to a wirelessly-controlled wearable ultrasonic nerve stimulation apparatus which includes: a user control terminal, a control emission chip, an ultrasonic energy transducer and a surface mount device housing. The user control terminal is intended for inputting a stimulation pulse mode and relevant stimulation waveform parameters, generating a corresponding control instruction and wirelessly transmitting the control instruction to the control emission chip. The control emission chip is intended for receiving the control instruction, generating a corresponding stimulation electric impulse waveform and driving the ultrasonic energy transducer. The ultrasonic energy transducer is intended for transforming the stimulation electric impulse waveform to an ultrasonic stimulation wave beam, and acting on a stimulation target. The surface mount device housing is intended for packaging the control emission chip and the ultrasonic energy transducer, and performing contact and fixing with the stimulation target. According to the invention, the apparatus realizes minimization and intelligent control of the stimulation apparatuses, and is in particular suitable for conducting long-time stimulation process on an acting target which is under normal free state.

The invention discloses a method for controlling movement of a woundless rat robot. The conventional animal robot has the defects of difficult development process and low success rate by adopting a creative movement control mode. The invention adopts a mode of integrating ultrasonic stimulation with epidermal electrode stimulation and LED light auxiliary stimulation, wherein the ultrasonic stimulation is used for stimulating sense of hearing; the epidermal electrode stimulation is used for stimulating sense of pain; and the LED light auxiliary stimulation is used for stimulating sense of vision to make the rat robot have active escape behavior so as to control the movement of the rat robot. The method for controlling movement by adopting a woundless rat movement control mode has the advantages of solving the problems of neurolysis, difficult operation and the like in creative stimulation control, accelerating practical process, along with no need of craniotomy on the rat, short development cycle, and wide development potential in aspects of personnel search and rescue, military activities, and acquisition of physiological parameters of organisms in the future.

The invention discloses an application of a tin disulfide/carbon nanofiber composite material in degradation of organic pollutants, which comprises the following steps: putting a carbon nanofiber membrane into a precursor solution containing a tin source and a sulfur source, reacting, and drying to obtain the tin disulfide/carbon nanofiber composite material, and putting the tin disulfide/carbon nanofiber composite material into water containing organic pollutants, and then carrying out ultrasonic treatment to remove the organic pollutants in the water. According to the method, different technical ideas are utilized, the purpose of catalytically degrading the organic pollutant bisphenol A through pure SnS2 is achieved, and in the catalytic process, SnS2 can efficiently remove the organic pollutant under ultrasonic stimulation.

The invention is suitable for the technical field of medical treatment, and provides an ultrasonic stimulation method and device, wherein the method comprises the steps: obtaining an ultrasonic stimulation target region of an organ; adjusting a fixed position of an ultrasonic transducer based on each stimulation detection point determined in the ultrasonic stimulation target area; determining a target stimulation target point from the stimulation detection points based on stimulation feedback results of ultrasonic stimulation at different fixed positions; and on the basis of the target stimulation target point, carrying out ultrasonic stimulation operation, wherein the convenience of finding the target point is improved, and the accuracy of the ultrasonic stimulation operation is improved.

The invention relates to a wearable mouse brain stimulation ultrasonic transducer. The wearable mouse brain stimulation ultrasonic transducer comprises a circulator and a piezoelectric array element;a backing block is embedded in the circulator; the piezoelectric array element is connected with the backing block; the piezoelectric array element includes a piezoelectric material layer; one side surface of the piezoelectric material layer has a concave surface, and the shape of the concave surface matches the outer contour shape of a mouse brain skull; an outer electrode is arranged on the concave surface; an inner electrode is arranged on the other side surface of the piezoelectric material layer; an installation hole for installation of an SMA interface is formed in the backing block; theouter electrode is electrically connected to a threaded electrode of the SAM interface; and the inner electrode is connected to a central electrode of the SAM interface. In the technical scheme, thetransducer can achieve focusing by using the concave surface, a large amount of energy is projected to a small area to achieve nerve stimulation; MRI is the highest monitoring method for biological tissue resolution in the prior art, the mouse brain is small, MRI detection can be performed during ultrasonic stimulation so as to achieve a similar real-time detection effect.

The invention discloses a non-invasive blood pressure regulation system based on ultrasonic nerve stimulation. The system comprises a blood pressure monitoring device, a central control circuit and anultrasonic stimulation device, wherein the blood pressure monitoring device is used for monitoring, displaying and storing the blood pressure, and sending the monitored blood pressure values to the central control circuit; the central control circuit is used for receiving the blood pressure values sent by the blood pressure monitoring device, switching different ultrasonic nerve stimulation modesaccording to the changing situations of the blood pressure values and outputting control instructions; the ultrasonic stimulation device is used for receiving the control instructions output by the central control circuit and conducting ultrasonic nerve stimulation in different ultrasonic nerve stimulation modes according to the control instructions so as to achieve blood pressure regulation. Theultrasonic stimulation device comprises a random waveform generator, a power amplifier, an impedance matcher, a switching selector, a focused ultrasonic transducer group and a signal feedback device.By means of the non-invasive blood pressure regulation system, while it can be achieved that the blood pressure is monitored in real time, non-invasive blood pressure regulation can be conducted according to a set blood pressure threshold, and the blood pressure is kept to be stable.

The invention discloses retina stimulation equipment based on two-dimensional array probes, and the equipment comprises a lens frame and the two-dimensional array probes, wherein the two-dimensional array probes are installed in the lens frame, and the lens frame is provided with a camera device, an integrated circuit, and a power supply. Coupling parts are disposed between the two-dimensional array probes and eyes. The camera device is used for collecting image information and transmitting the image information to the integrated circuit. The integrated circuit is used for converting the image information into an electric signal and transmitting the electric signal to the two-dimensional array probes. The two-dimensional array probes are used for generating ultrasound under the excitation of the electric signal, and achieving the ultrasonic stimulation of the retinas. The power supply is used for supplying power to the camera device and the integrated circuit. After a dysopia person wears the equipment, the integrated circuit enables the image information collected by the camera device to be converted into the electric signal, and the electric signal is used for the excitation of the two-dimensional array probes, thereby forming a focused sound beam with a plurality of focuses. The ultrasound acts on optic nerve cells, and enables the dysopia person to sense the image information, and to recover the visual sensing function.

The invention provides a tartarian buckwheat seedling health-care beverage rich in flavone and a making method of the tartarian buckwheat seedling health-care beverage. The tartarian buckwheat seedling health-care beverage contains 20%-45% of tartarian buckwheat juice, 20%-35% of licorice root juice, 20%-35% of honeysuckle flower juice, 0.05%-0.1% of citric acid, 0.01-0.025% of malic acid, 0.01%-0.025% of sodium citrate, 3%-8% of xylitol, 3%-6% of trehalose, 0.005%-0.01% of ethyl maltol and 0.2%-0.4% of a composite stabilizer, wherein the total of the raw materials is 100%. Compared with the prior art, the tartarian buckwheat seedling health-care beverage rich in flavone provided by the invention has the advantages that flavone-enriched tartarian buckwheat seedlings which are obtained through ultrasonic stimulation and illumination culture, licorice roots and honeysuckle flowers are used as the raw materials, the xylitol and the like which have the effect of reducing blood sugar are used as auxiliary materials, the content of the flavone reaches 550-570mg/L, the tartarian buckwheat seedling health-care beverage has health-care functions, and requirements of consumers for mouth feeland health are met.

The invention provides a closed-loop transcranial brain stimulation system and method. The system comprises a transcranial ultrasonic signal generation module, a transcranial ultrasonic stimulation module, an electroencephalogram and electromyogram signal acquisition and processing module and an electrode module; the electrode module is used for collecting brain muscle signals of an experimental subject; the electroencephalogram and electromyographic signal collecting and processing module is configured to be used for collecting signals of the electrode module, processing the signals and then sending detection signals to the transcranial ultrasonic signal generating module; the transcranial ultrasonic signal generation module is configured to receive the detection signal, generate a stimulation signal according to the detection signal and an adjustment strategy, and send the stimulation signal to the transcranial ultrasonic stimulation module; the transcranial ultrasonic stimulation module is configured to emit ultrasonic stimulation to the experimental subject according to the stimulation signal. The beneficial effects of the invention are that the transcranial ultrasonic signal generation module adjusts the signal parameters of the transcranial ultrasonic stimulation module to the experimental subject next time according to the brain and muscle signals collected by the electrode module and a system expected value through a configuration strategy, thereby achieving the closed-loop control of the transcranial brain stimulation.

The invention relates to an ultrasonic stimulation device and ultrasonic stimulation method for promoting proliferation and differentiation of spinal cord-derived neural stem cells. The device is provided with a power supply, a driving signal generator, a pulse repetition frequency generator, a power amplifier, an ultrasonic probe and a hydrophone, wherein the driving signal generator converts a common current into a high-frequency current, the pulse repetition frequency generator generates a pulse signal with a repetition frequency from the high-frequency current, the power amplifier amplifies the pulse signal, and finally the ultrasonic probe emits an ultrasonic wave from the amplified pulse signal, the hydrophone is used for receiving acoustic signals in liquid, the ultrasonic probe iscylindrical and an isolation vessel is arranged above the ultrasonic probe. According to the method, primary cultured spinal cord-derived neural stem cells are subjected to ultrasonic stimulation at an intensity of 10-150 mW/cm2. The method is suitable for researching influence of ultrasound on the proliferation and differentiation of the spinal cord-derived neural stem cells. The device utilizeslow-frequency pulse ultrasound to stimulate the spinal cord-derived neural stem cells, promotes the proliferation and differentiation of the spinal cord-derived neural stem cells, and further promotesrepair of spinal cord injury.

A guide framework for positioning an ultrasonic transducer which emits a focused ultrasound to a target point in carrying out surgery to apply ultrasonic stimulation to a subject's brain, includes a body in a shape of a mask that is laid on the subject's face, and a positioning hole formed through an inner surface and an outer surface of the mask body, the positioning hole into which the ultrasonic transducer is inserted, wherein the inner surface of the mask body is formed to conform a facial contour of the subject, and when the guide framework is laid on the subject's face and the ultrasonic transducer is disposed at the positioning hole, the position of the target point is naturally disposed at a preset stimulation site of the brain. An ultrasonic stimulation device includes an ultrasonic transducer and the guide framework for positioning the ultrasonic transducer.

The invention relates to an intensified biological treatment device and method for degradation-resistant organic nitrogen-rich chemical wastewater. The intensified biological treatment method comprises the following steps that when wastewater enters a water distributor from a water inlet system, sprinkled into the bottom of a hydrolytic acidification reactor, then flows into a water outlet system from bottom to top, and enters an anoxic zone of a membrane bioreactor; under the action of electrodes, the wastewater enhances the activity of denitrifying bacteria, and nitrogen removal by denitrification is achieved; the wastewater then enters an aerobic zone of the membrane bioreactor, ultrasound generated by an ultrasonic generator is transmitted into an energy converter, and ultrasonic stimulation is conducted on the wastewater to remove organic materials and ammonia nitrogen; the wastewater is pumped out of the membrane bioreactor though a membrane module and enters a water outlet end. The synergistic effect of hydrolytic acidification and the membrane bioreactor is fully utilized, the biodegradability can be improved by hydrolytic acidification, and the problems that degradation is difficult in the aerobic process, the organic materials are slow in degradation and organic loading is low are avoided; then the sludge concentration is improved by means of the membrane bioreactor, and the organic materials and ammonia nitrogen are further degraded.