48 results about "Sonication" patented technology

Among other things, in general, methods, apparatus, systems, and compositions are provided for rendering bone tissue sufficiently acoustically transparent for ultrasound imaging or ultrasound therapy or both. The bone tissue is rendered acoustically transparent by use of a decalcifying treatment (with or without concomitant sonication) within a pre-thinned cavity of bone. Ultrasound imaging and therapy examining a region of interest within brain, spinal column, carpal tunnel, etc. is thereby enabled.

The present disclosure provides an in-vitro method of universal microbial lysis compatible with hybridization-based nucleic acid enrichment and extraction methods, comprising the steps of: (a) subjecting a sample to a combination of lysis steps to obtain a lysed sample, wherein the combination of lysis steps is selected from the group consisting of: (i) an ultrasound sonication, (ii) a combination of multiple sonication steps,- (iii) a combination of enzymatic treatment and one or more sonication steps, and (iv) a combination of enzymatic treatment, one or more sonication steps, and thermal step; and (b) treating the lysed sample of step (a) with one or more enzymes, followed by sonication for microbial lysis.

A method of preparing viable stromal and mesenchymal stem cells from adipose tissue that produces high quality and high counts of stem cells with a low risk of contamination. The apparatus provides ultrasonic waves through a constant temperature bath to the tissue held in a sterile sonication container such as a test tube or jar. No sonication probe touches the tissue or the cells during the process. The stem cells produced are ready to be administered to a patient.

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

An ultrasonic mist inhaler, including a liquid reservoir structure including a liquid chamber adapted to receive liquid to be atomized, the liquid chamber including a top surface representing a maximum level of the liquid chamber and a bottom surface representing a minimum level of the liquid chamber, a sonication chamber in fluid communication with the liquid chamber, the sonication chamber includes a piezoelectric transducer and a capillary material extending between the sonication chamber and the liquid chamber, wherein the piezoelectric transducer and the liquid chamber are arranged according to one of the following configurations: the piezoelectric transducer is disposed close to or at the bottom surface of the liquid chamber, the piezoelectric transducer is disposed close to or at the top surface of the liquid chamber as depicted in FIG. 3.

A mist generator device (400) for delivering a mist to a user, the mist generator device (400) for use with a driver device (202). The mist generator device (400) comprises a housing (204) comprising a liquid chamber (218), the liquid chamber containing a liquid to be atomised, the liquid comprising a therapeutic. A sonication assembly (425) is coupled to the housing (204) the sonication assembly (425) comprising an ultrasonic transducer (215), a first assembly portion (426) and a second assembly portion (428) coupled to the first assembly portion (426). At least one of the first assembly portion (426) and the second assembly portion (428) comprises a resiliently deformable section that forms a seal between the first assembly portion (426) and the second assembly portion (428) which minimises or prevents a fluid from leaking between the first assembly portion (426) and the second assembly portion (428).

A cell lysis device comprising: a housing comprising: an opening to receive a sample container such that the opening is closed by the container to seal the housing; and an interference fit attachment

The invention relates to an ultrasonic mist inhaler, comprising:a liquid reservoir structure comprising a liquid chamber adapted to receive liquid to be atomized,the liquid chamber comprising a top surface representing the maximum level of the liquid chamber and the bottom surface representing the minimum level of the liquid chamber,a sonication chamber in fluid communication with the liquid chamber,the sonication chamber comprising means of ultrasonic vibrations and a capillary element extending between the sonication chamber and the liquid chamber,wherein the means of ultrasonic vibrations and the liquid chamber are arranged according to one of the following configurations:the means of ultrasonic vibrations are disposed close to or at the bottom surface of the liquid chamber,the means of ultrasonic vibrations are disposed close to or at the top surface of the liquid chamber as depicted in FIG. 3.

A method for of ultrasonically impregnating nanoparticle into the fabric is provided. Further, systems for use in ultrasonically impregnation of fabrics are also provided.

A process for preparing a composition from graphite material by contacting the graphite material with a main solvent comprising at least 10% by weight, with respect to a total weight of the main solvent, of a vinyl aromatic monomer alone or in a mixture up to 50% by weight with additional copolymerizable monomers, thereby forming a starting composition; subjecting to an ultrasound treatment with a frequency spectrum ranging between 18 kHz and 1000 kHz, at a pressure equal to or higher than 2 bar absolute and in a container or sonication chamber wherein no separated phase of fluid at the gaseous phase contacts said composition; and polymerizing at least 1% of the vinyl aromatic monomer present in the main solvent, wherein the composition is at least partially polymerized and contains graphene and graphene nanoplatelets durably dispersed in the solvent, and the composition is without any evident formations of deposits or separated phases for at least 30 days.

A pod for use with a mist inhalation device. The pod comprises a housing having a first end, an opposite second end and at least one side wall. A liquid barrier is provided. A spacer is positioned within the housing and includes a hollow interior surrounded by a perimeter, the interior partly defining a sonication chamber. An ultrasonic transducer is positioned between the spacer and the second end, and a capillary extends between the liquid chamber and the sonication chamber. An air inlet conduit and a mist outlet conduit each form a channel for conducting air through the liquid chamber and the liquid contained therein.

Abstract A mist generator device (400) for delivering a mist to a user, the mist generator device (400) for use with a driver device (202). The mist generator device (400) comprises a housing (204) comprising a liquid chamber (218) for containing a liquid to be atomised, a sonication assembly (425) coupled to the housing (204) the sonication assembly (425) comprising an ultrasonic transducer (215).a first assembly portion (426) and a second assembly portion (428) coupled to the first assembly portion (426). At least one of the first assembly portion (426) and the second assembly portion (428) comprises a resiliently deformable section that forms a seal between the first assembly portion (426) and the second assembly portion (428) which minimises or prevents a fluid from leaking between the first assembly portion (426) and the second assembly portion (428). 20 26 20 52 81 03 J ul 2 02 6 2 0 2 6 2 0 5 2 8 1 0 3 J u l 2 0 2 6

Various approaches for heating a target region substantially uniformly include identifying one or more locations of one or more hot spots in the target region and / or surrounding regions of the target region during an ultrasound sonication process; computing a temporal variation to an output parameter of at least one of the transducer elements based at least in part on the identified location(s) of the hot spot(s); and operating the at least one transducer element to achieve the temporal variation of the output parameter so as to minimize the hot spot(s).

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

The invention belongs to the field of environmental pollution remediation, and particularly relates to a ZnMoO4 / CoMoO4 composite material, a preparation method thereof and application of the ZnMoO4 / CoMoO4 composite material in catalytic ultrasonic degradation of RhB. The preparation method comprises the following steps: stirring a mixed solution of ZnCl2 and CoMoO4; adding a Na2MoO4. 2H2O solution into the system according to the mass ratio of ZnMoO4 to CoMoO4, and carrying out ultrasonic treatment; carrying out hydrothermal reaction; and carrying out suction filtration, washing and drying on the obtained reactant to obtain ZnMoO4 / CoMoO4 compounds with different mass ratios. The ZnMoO4 / CoMoO4 composite material prepared by the invention is combined with ultrasound to degrade RhB in water, and when the ultrasonic power is 500W and the ultrasonic time is 120min, the degradation rate of RhB in water can reach 92.78 (+ / -0.44)%.

An AI-supported, feedback-regulated ultrasonic anchoring system for the self-regulating ultrasonic anchoring of nanoparticles on polymer-carbon nanocomposites, comprising: a reaction chamber designed to hold a mixture of a polymer, a carbon material and nanoparticles; an ultrasound generator integrated into the reaction chamber, configured to expose the mixture to ultrasound irradiation; at least one sensor that is operationally connected to the ultrasound generator and is configured to continuously measure at least one system response parameter in situ during ultrasound irradiation, wherein the system response parameter changes depending on the anchoring of the nanoparticles on the polymer-carbon framework, and wherein the sensor is further configured to transmit the measured data of the system response parameter in real time; a control unit configured to receive and evaluate the system response parameter measured by the sensor, the control unit further being configured to automatically terminate or modulate the ultrasonic irradiation upon detection of the stabilized or saturated state; and a feedback control module operationally connected to the control unit, configured to detect when the system response parameter reaches a stabilized or saturated state within a predefined tolerance range, whereby the duration of the ultrasonic irradiation is determined exclusively by the measured system response parameter and not by a predetermined sonication time.

A method for regenerating a CO2-rich solvent includes producing a low-frequency ultrasound proximate the CO2-rich solvent, inducing convective mixing of the CO2-rich solvent, reducing a viscosity of the CO2-rich solvent, and releasing CO2 gas from the CO2-rich solvent. Additionally, a system for solvent regeneration includes at least one regeneration intensification unit, including an ultrasonic processor designed to apply sonication to the solvent, a transducer physically coupled to the ultrasonic processor, a horn physically coupled to the transducer, and a sonication reaction chamber physically coupled to the horn and fluidly coupled to a flask retaining the solvent, where the solvent is cycled between the flask and the sonication reaction chamber. Furthermore, a system for solvent regeneration includes a reboiler, a regenerator, a heat exchanger, an absorber, and at least one ultrasonic processor designed to apply sonication to the solvent.

Various approaches for computationally characterizing tissue in an anatomic target region include generating multiple sonications to transient acoustic reflectors at or proximate to the target region; measuring reflection signals of the sonications off the transient acoustic reflectors; based on the measurements, identifying the reflection signals originating from single transient acoustic reflectors; and based at least in part on the identified reflection signals, generating a digital map including a tissue characteristic.

The invention relates to an ultrasonic mist inhaler, comprising a liquid reservoir structure comprising a liquid chamber adapted to receive liquid to be atomized, a sonication chamber in fluid communication with the liquid chamber; wherein the liquid reservoir structure comprises the sonication chamber as depicted in FIG. 3.

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

Reduced Graphene Oxide was synthesized by treatment of Graphite using only H2SO4 acid, KMnO4, H2O2 and H2O, adopting the method disclosed herein, where the mix of Graphite, H2SO4 acid and KMnO4 was subjected to sonication and stirring while maintaining the temperature at < 80°C for GO / rGO composite and > 80°C for rGO followed by addition of water and H2O2 to stop the oxidation / reduction reaction. A separate reductant was not used during reduction stage and vibrational energy of the ultrasonic cell disruptor caused the detachment of functional group from GO at given temperature to form rGO. Analytical techniques such as XRD, XPS, Raman and FTIR were used to confirm the presence of reduced Graphene Oxide and Graphene Oxide.

A pod for use with a mist inhalation device, the pod comprising a housing having a first end, an opposite second end and at least one side wall. A liquid barrier is provided. A spacer is positioned within the housing and includes a hollow interior surrounded by a perimeter, the interior partly defining a sonication chamber. An ultrasonic transducer is positioned between the spacer and the second end, and a capillary extends between the liquid chamber and the sonication chamber. An air inlet conduit and a mist outlet conduit each form a channel for conducting air through the liquid chamber and the liquid contained therein.

An ultrasonic mist inhaler, including a liquid reservoir structure including a liquid chamber adapted to receive liquid to be atomized, a sonication chamber in fluid communication with the liquid chamber, a capillary material arranged between the liquid chamber and the sonication chamber, the sonication chamber including an ultrasonic oscillation component having an atomization surface, a capillary material retainer, wherein the capillary material retainer having a body surrounding the ultrasonic oscillation component, the retainer body having a radial arm extending to the atomization surface for retaining the capillary material in surface contact with the atomization surface.

Disclosed are a dry-coupling ultrasonic transducer that can deliver either focused and non-focused ultrasound to the brain without the use of hydrogel or degassed water as coupling media, while minimizing acoustic distortion, and a wide-area transcranial ultrasound sonication device that incorporates the ultrasonic transducer. The ultrasonic transducer includes a main body configured to generate ultrasound and a dry acoustic coupler configured to transmit the ultrasound to a sonication target, wherein the coupler includes a plurality of flexible coupling pins extending from the front surface of the transducer main body, to provide direct contact with the sonication target.

A stereotactic device wearable by a patient for low-intensity focused-ultrasound neuromodulation has a support frame shaped to be fitted around a head of the patient, a first movable component having an arched shape and having a first end and a second end engaged with the support frame at respective first and second coupling points. A second movable component has an engagement portion with the first movable component adapted to allow the second movable component to move integrally with the first movable component and to slide along the first movable component to take a plurality of positions between a first position in which the second movable component is proximal to the first end and a second position in which the second movable component is proximal to the second end. A low-intensity focused-ultrasound neuromodulation module housed in a support portion of the second movable component has a low-intensity focused-ultrasound sonication probe.

The present disclosure relates to a device for sonicating a biological sample. In one embodiment, a sample tube holder is pivotally suspended in a mount of a sonication device, thus allowing for a rotational degree of freedom and / or lateral movement that provides an optimized contact area between the sonotrode and the sample tube. Also disclosed is a method for sonicating a biological sample using the device described herein.

The invention relates to a personal ultrasonic atomizer device 10, which includes a cartridge 12 having a reservoir 26 for holding a liquid to be atomized, which is interchangeable prior to complete discharging of the reservoir 26 and includes an anti-tamper and anti-counterfeiting safeguard, a sonication chamber 14, placed in fluid communication with the reservoir 26, and for cavitating a liquid placed in contact with a piezoelectric oscillation piece 112; such that vape and / or mist is generated without combustion and / or heating of the liquid, where the device 10 includes a liquid retention means 76 for allowing use of the device in any orientation, and where the device is controllable by an external electronic device.

Dental treatment device includes a wand having an applicator. A neck connector is provided between the wand and the applicator. An ultrasonic resonator; is provided and the ultrasonic resonator generates ultrasonic vibration in the applicator. The applicator generates ultrasonic vibration of a surface of an open cell foam. The open cell foam being impregnated with a solution and placed in contact with a surface of an individual human tooth.

Various approaches for computationally generating a protocol for treatment of one or more target BBB regions within a tissue region of interest using a source of focused ultrasound include specifying (i) settings of sonication parameters for applying one or more sequence of sonications to the target BBB region using the source of focused ultrasound and (ii) a characteristic of microbubbles selected to be administered into the target BBB region; electronically simulating treatment in accordance with the protocol at least in part by computationally executing the sequence(s) of sonications and computationally administering the microbubbles having the characteristic; and computationally predicting a tissue disruption effect of the target BBB region resulting from the treatment.

A system can include a vessel having a plurality of sonication devices for separating a base hydrocarbon mixture that is disposed in the vessel. The sonication devices can be mounted on opposing walls of the vessel. A mixer can establish a flow of the vessel mixture within the vessel that increases exposure of the mixture to ultrasonic waves emitted by the sonication devices and carried in the water matrix. The flow of the vessel mixture within the vessel also facilitates removal of oil from the vessel mixture.