23 results about "Sonication" patented technology

The present disclosure provides an in-vitro method of universal microbial lysis compatible with hybridization-based nucleic acid enrichment and extraction methods, comprising the steps of: (a) subjecting a sample to a combination of lysis steps to obtain a lysed sample, wherein the combination of lysis steps is selected from the group consisting of: (i) an ultrasound sonication, (ii) a combination of multiple sonication steps,- (iii) a combination of enzymatic treatment and one or more sonication steps, and (iv) a combination of enzymatic treatment, one or more sonication steps, and thermal step; and (b) treating the lysed sample of step (a) with one or more enzymes, followed by sonication for microbial lysis.

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

A process for preparing a composition from graphite material by contacting the graphite material with a main solvent comprising at least 10% by weight, with respect to a total weight of the main solvent, of a vinyl aromatic monomer alone or in a mixture up to 50% by weight with additional copolymerizable monomers, thereby forming a starting composition; subjecting to an ultrasound treatment with a frequency spectrum ranging between 18 kHz and 1000 kHz, at a pressure equal to or higher than 2 bar absolute and in a container or sonication chamber wherein no separated phase of fluid at the gaseous phase contacts said composition; and polymerizing at least 1% of the vinyl aromatic monomer present in the main solvent, wherein the composition is at least partially polymerized and contains graphene and graphene nanoplatelets durably dispersed in the solvent, and the composition is without any evident formations of deposits or separated phases for at least 30 days.

A pod for use with a mist inhalation device. The pod comprises a housing having a first end, an opposite second end and at least one side wall. A liquid barrier is provided. A spacer is positioned within the housing and includes a hollow interior surrounded by a perimeter, the interior partly defining a sonication chamber. An ultrasonic transducer is positioned between the spacer and the second end, and a capillary extends between the liquid chamber and the sonication chamber. An air inlet conduit and a mist outlet conduit each form a channel for conducting air through the liquid chamber and the liquid contained therein.

Abstract A mist generator device (400) for delivering a mist to a user, the mist generator device (400) for use with a driver device (202). The mist generator device (400) comprises a housing (204) comprising a liquid chamber (218) for containing a liquid to be atomised, a sonication assembly (425) coupled to the housing (204) the sonication assembly (425) comprising an ultrasonic transducer (215).a first assembly portion (426) and a second assembly portion (428) coupled to the first assembly portion (426). At least one of the first assembly portion (426) and the second assembly portion (428) comprises a resiliently deformable section that forms a seal between the first assembly portion (426) and the second assembly portion (428) which minimises or prevents a fluid from leaking between the first assembly portion (426) and the second assembly portion (428). 20 26 20 52 81 03 J ul 2 02 6 2 0 2 6 2 0 5 2 8 1 0 3 J u l 2 0 2 6

Various approaches for heating a target region substantially uniformly include identifying one or more locations of one or more hot spots in the target region and / or surrounding regions of the target region during an ultrasound sonication process; computing a temporal variation to an output parameter of at least one of the transducer elements based at least in part on the identified location(s) of the hot spot(s); and operating the at least one transducer element to achieve the temporal variation of the output parameter so as to minimize the hot spot(s).

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

An AI-supported, feedback-regulated ultrasonic anchoring system for the self-regulating ultrasonic anchoring of nanoparticles on polymer-carbon nanocomposites, comprising: a reaction chamber designed to hold a mixture of a polymer, a carbon material and nanoparticles; an ultrasound generator integrated into the reaction chamber, configured to expose the mixture to ultrasound irradiation; at least one sensor that is operationally connected to the ultrasound generator and is configured to continuously measure at least one system response parameter in situ during ultrasound irradiation, wherein the system response parameter changes depending on the anchoring of the nanoparticles on the polymer-carbon framework, and wherein the sensor is further configured to transmit the measured data of the system response parameter in real time; a control unit configured to receive and evaluate the system response parameter measured by the sensor, the control unit further being configured to automatically terminate or modulate the ultrasonic irradiation upon detection of the stabilized or saturated state; and a feedback control module operationally connected to the control unit, configured to detect when the system response parameter reaches a stabilized or saturated state within a predefined tolerance range, whereby the duration of the ultrasonic irradiation is determined exclusively by the measured system response parameter and not by a predetermined sonication time.

A mist inhaler pod for use with a driver. The pod comprises a housing, a liquid barrier wall positioned within the housing having at least one liquid channel, and a liquid chamber defined by the liquid barrier wall and the housing. The pod further includes a spacer positioned within the housing, and a fluid flow manifold provided within the spacer. A sonication chamber is included within a cavity of the fluid flow manifold. An ultrasonic transducer is in communication with the sonication chamber, and a capillary conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit conducts mist from the sonication chamber to the mist outlet port.

A pod for use with a mist inhalation device, the pod comprising a housing having a first end, an opposite second end and at least one side wall. A liquid barrier is provided. A spacer is positioned within the housing and includes a hollow interior surrounded by a perimeter, the interior partly defining a sonication chamber. An ultrasonic transducer is positioned between the spacer and the second end, and a capillary extends between the liquid chamber and the sonication chamber. An air inlet conduit and a mist outlet conduit each form a channel for conducting air through the liquid chamber and the liquid contained therein.

Disclosed are a dry-coupling ultrasonic transducer that can deliver either focused and non-focused ultrasound to the brain without the use of hydrogel or degassed water as coupling media, while minimizing acoustic distortion, and a wide-area transcranial ultrasound sonication device that incorporates the ultrasonic transducer. The ultrasonic transducer includes a main body configured to generate ultrasound and a dry acoustic coupler configured to transmit the ultrasound to a sonication target, wherein the coupler includes a plurality of flexible coupling pins extending from the front surface of the transducer main body, to provide direct contact with the sonication target.

A stereotactic device wearable by a patient for low-intensity focused-ultrasound neuromodulation has a support frame shaped to be fitted around a head of the patient, a first movable component having an arched shape and having a first end and a second end engaged with the support frame at respective first and second coupling points. A second movable component has an engagement portion with the first movable component adapted to allow the second movable component to move integrally with the first movable component and to slide along the first movable component to take a plurality of positions between a first position in which the second movable component is proximal to the first end and a second position in which the second movable component is proximal to the second end. A low-intensity focused-ultrasound neuromodulation module housed in a support portion of the second movable component has a low-intensity focused-ultrasound sonication probe.

Dental treatment device includes a wand having an applicator. A neck connector is provided between the wand and the applicator. An ultrasonic resonator; is provided and the ultrasonic resonator generates ultrasonic vibration in the applicator. The applicator generates ultrasonic vibration of a surface of an open cell foam. The open cell foam being impregnated with a solution and placed in contact with a surface of an individual human tooth.

A system can include a vessel having a plurality of sonication devices for separating a base hydrocarbon mixture that is disposed in the vessel. The sonication devices can be mounted on opposing walls of the vessel. A mixer can establish a flow of the vessel mixture within the vessel that increases exposure of the mixture to ultrasonic waves emitted by the sonication devices and carried in the water matrix. The flow of the vessel mixture within the vessel also facilitates removal of oil from the vessel mixture.

A mist inhaler pod (10) for use with a driver. The pod comprises a housing (11), a liquid barrier wall (20) positioned within the housing having at least one liquid channel (26), and a liquid chamber (25) defined by the liquid barrier wall and the housing. The pod further includes a spacer (21) positioned within the housing, and a fluid flow manifold (22) provided within the spacer. A sonication chamber (42) is included within a cavity (41) of the fluid flow manifold. An ultrasonic transducer (23) is in communication with the sonication chamber, and a capillary (24) conducts liquid from the liquid chamber to the sonication chamber. An air inlet conduit forms an air-tight channel for conducting air form an air inlet to the sonication chamber, and a mist outlet conduit (46) conducts mist from the sonication chamber to the mist outlet port.

This invention relates to a method for obtaining nano-calcium hydroxide by mixing commercially available calcium hydroxide (micron-sized large particles) with ethyl acetate, allowing it to stand, and then washing, sonicating, rinsing, and centrifuging. The method involves a slow reaction of large-particle calcium hydroxide with ethyl acetate, generating calcium acetate within the large-particle calcium hydroxide. The calcium acetate is then washed away, exposing numerous tiny cracks in the calcium hydroxide particles. Ultrasonic sonication causes the calcium hydroxide particles to split at these cracks, and centrifugation separates them to obtain nano-calcium hydroxide. The nano-calcium hydroxide prepared by this method has a size of ~10 nm and relatively uniform particle size. More importantly, the method is extremely simple, requiring no heating or other complex operations, and has good prospects for widespread application.

A cell lysis device that uses ultrasound to lyse cells.SOLUTION: A cell lysis device comprising: a housing; a sonication chamber provided in the housing, the sonication chamber being at least partially filled with an ultrasound transmitting medium, the housing including an opening configured to receive a sample container such that a portion of the sample container protrudes into the ultrasound transmitting medium; and an ultrasonic transducer for generating ultrasonic waves in the ultrasound transmitting medium in the sonication chamber, the ultrasonic transducer comprising: An ultrasonic transducer, wherein ultrasonic waves are transmitted from the ultrasonic transducer to the sample container by an ultrasonic transmission medium to lyse cells when the cells are contained in the sample container.SELECTED DRAWING: Figure 3

A mist inhaler including a pod and a driver, the pod comprising: a housing having a first end, an opposite second end and at least one side wall extending therebetween; a liquid chamber containing a liquid comprising a therapeutic; a spacer including a hollow interior surrounded by a perimeter; a fluid flow manifold positioned at least partially within the hollow interior of the spacer and including a first side proximate the first end wall, and a second side proximate the second end wall, the first side of the fluid flow manifold including a channel and a cavity, the cavity including a first aperture for allowing fluid flow in a first direction, and one or more further apertures for allowing fluid flow in a second direction; a sonication chamber including the cavity of the fluid flow manifold; an ultrasonic transducer; an air inlet conduit; anda mist outlet conduit; the driver comprising: a driver casing having an air intake aperture; a casing recess; electronic components configured to generate control signals to control the operation of the pod, and drive signals to drive the pod to generate a mist; and a bulkhead positioned within the casing recess, the bulkhead including: a body including a portion that extends from the top surface to form a seal; a plurality of apertures formed in the body and positioned in an area at least partly surrounded by the seal; and a bulkhead intake conduit in airtight fluid communication with the air intake aperture and with a first aperture of the plurality of apertures, the bulkhead intake conduit being configured to conduct air from the air intake aperture to the pod through the first aperture of the plurality of apertures in the bulkhead; wherein, when the driver is coupled to the pod, a part of the pod is received into the casing recess, the seal of the driver contacting the part of the pod forming a substantially airtight seal therebetween to prevent air leaking out from between the bulkhead and the part of the pod.

Implementations are described herein that include placing an amount of liquid metal into a container and applying sound energy at one or more locations of the container while the metal cools. Articles can be formed that include a bulk region and one or more modified regions proximate to boundaries of the articles that correspond to the one or more locations at which the sound energy was applied.

Various approaches for computationally characterizing tissue in an anatomic target region include generating multiple sonications to transient acoustic reflectors at or proximate to the target region; measuring reflection signals of the sonications off the transient acoustic reflectors; based on the measurements, identifying the reflection signals originating from single transient acoustic reflectors; and based at least in part on the identified reflection signals, generating a digital map including a tissue characteristic.

Treatment planning and aberration correction algorithms for high intensity focused ultrasound (Hifu) ablation of soft tissue targets, and associated systems and methods are described. In one embodiment, a method for planning a sonication treatment of a target in a body includes obtaining a 3D anatomical model of the target and a portion of the body that is disposed between an ultrasound transducer and the target, where the ultrasound transducer is a phased array ultrasound transducer comprising a plurality of elements. The method also includes: selecting a position of the ultrasound transducer by applying a transducer positioning algorithm for optimizing a sonication geometry; and simulating an aberrated ultrasound field at the target, where the aberrated ultrasound field is a linear high-intensity focused ultrasound (HIFU) field. The method also includes compensating for phase aberrations of the aberrated ultrasound field by: backpropagating an ultrasound field from a virtual point source at the target, through the portion of the body that is disposed between the ultrasound transducer and the target, toward the ultrasound transducer, where the ultrasound field is spherical at the virtual point; and, based on backpropagating the ultrasound field from the virtual point, determining time delays at the elements of the ultrasound transducer, where the time delays are configured for compensating the phase aberrations of the ultrasound field at the virtual point source.

1. Name of the designed product: cleaner (rabbit small high-frequency sound wave vibration). 2. Use of the designed product: for cleaning contact lenses. 3. Design points of the designed product: in shape. 4. Picture or photo best indicating the design points: perspective view 1.

The present disclosure includes systems, devices, and methods for a reactor, such as a sonication reactor, for destruction of Per- and polyfluoroalkyl substances (PFASs). In one aspect of the disclosure, the reactor includes a housing having a base and one or more walls that cooperate to define a chamber and a transducer disposed the chamber. The transducer is configured to generate a plurality of sound waves such that when PFAS solution is disposed within the chamber, the sound waves propagate through the liquid and at least some of the one or more PFAS compounds are pyrolyzed or otherwise degraded. Other aspects and features are also claimed and described.