The invention provides a lock capable of locking a high-definition video connector and a design method thereof, and relates to the technical field of electric connectors, the lock comprises a lock body, one end of the lock body is provided with a male head end, the other end of the lock body is provided with a female seat end, the male head end comprises a male head shell, a rubber core is arranged in the male head shell, and two first connecting pieces are arranged on one side of the rubber core; the first connecting piece comprises a first lock rod, one end of the first lock rod extends out of the first through hole, the female seat end comprises a female seat shell, a second connecting piece is arranged outside the female seat shell and comprises a second lock rod, one end of the second lock rod extends into the female seat shell, and a driving mechanism is arranged on the connecting shell. The driving mechanism is used for driving the first connecting piece and the second connecting piece to rotate synchronously. According to the high-definition video connector, the male head of the high-definition video connector is connected with the female seat of the equipment through the lock body, the reliability of connection between the high-definition video connector and the equipment is improved by arranging the independent lock body, the high-definition video connector does not need to be transformed, and the use cost is reduced.