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1055 results about "Living body" patented technology

MES system login authentication method based on face recognition technology

The invention discloses an MES (Manufacturing Execution System) login authentication method based on a face recognition technology, which relates to the technical field of industrial information security, and comprises the following steps of: constructing an authentication data acquiring a face image of an authorized user of an MES, extracting a reference face feature template after preprocessing, and constructing the authentication database; performing associated storage on the reference feature template, user identity information, preset operation authority and affiliated production station information to form an authentication database; according to the method, spoofing attacks are prevented through multi-mode living body detection, and the problem that a traditional password / key is easy to leak and borrow is solved in combination with uniqueness of human face biological characteristics; a person-post-terminal binding mechanism further limits permission abuse, and internal operation risks are reduced; the non-contact authentication does not need to memorize a password or carry a physical key, and is suitable for a working scene that a workshop operator wears gloves and holds tools; and the recognition passing rate in a complex industrial environment is improved through dynamic threshold optimization.
Owner:HUBEI UNIV FOR NATITIES

User Authentication, Spoofing and Replay Attack Prevention, Liveness Detection, and User-and-Document Verification using a Live Video Stream with Spatial Challenges

User authentication, spoofing and replay attack prevention, liveness detection, and user-and-document verification using a live video stream with spatial challenges. A camera of an electronic device captures and transmit a live selfie user-facing video, as part of a user registration process. The user is instructed to spatially move his body or face, such that his face would appear within a first particular on-screen shape; and to also, concurrently or simultaneously, spatially hold in his hand or move a particular an identification document such that it would appear within a second on-screen shape. Optionally, the on-screen shape moves on the screen, and the user is required to spatially move the relevant item to keep it within the boundaries of the moving on-screen shape. The system then analyzes the video via computerized vision, to determine whether the user complied with the spatial manipulation challenges.
Owner:IRONVEST INC

Multi-cell living body material constructed by adopting droplet bioreactor and method thereof

The invention discloses a method for constructing a multicellular living body material by adopting a droplet bioreactor, which belongs to the crossing field of biological materials and microbial engineering, and comprises the following steps: (1) resuspending different cells in different polymer solutions to prepare degradable or phase-separable hydrogel particles containing cells; (2) dispersing the hydrogel particles in a cross-linkable hydrogel matrix to form a composite hydrogel; and (3) curing the composite hydrogel, and then carrying out degradation treatment to obtain the liquid cavity structure multicellular system bioreactor with spatial partition and dynamic interaction characteristics. According to the invention, ordered distribution and metabolism synergy of different microorganisms in space can be realized, controllable degradability and excellent mass transfer performance are realized, bacterial slow release and metabolite exchange can be maintained, and the method is suitable for long-term stable operation of a continuous flow reactor. The method has wide application prospects in the fields of green biological manufacturing, renewable energy source production, environmental restoration, biomedical engineering and the like.
Owner:NANJING TECH UNIV

Narrow-body self-walking operation platform with hybrid power system

The invention belongs to the technical field of electric overhead working trucks, and provides a narrow-body self-walking working platform with a hybrid power system, which comprises a walking platform, a working device and a control system. The walking platform adopts a narrow-body four-wheel-drive chassis and is provided with a hybrid power system of a fuel engine and an electric pump, and the control system integrates an environment sensing unit, a stability calculation unit, a track prediction unit, an early warning unit and a control decision unit. The environment sensing unit constructs a high-precision three-dimensional environment map; the stability calculation unit calculates the overall gravity center position and the dynamic stability boundary of the platform in real time; the track prediction unit establishes a dynamic hydraulic system response model; and the early warning unit adopts an artificial potential field method to calculate a safety avoidance path. And the control decision unit automatically adjusts the control instruction according to the risk type and degree. According to the invention, the organic combination of environment perception, dynamic stable control, prediction trajectory planning and electrified body safety protection is realized, and the operation safety and efficiency of the aerial work platform are obviously improved.
Owner:QINGDAO HAIKIN VEHICLES CO LTD

Soft-shell crab transportation method

The invention belongs to the technical field of aquatic product living body transportation, and particularly relates to a soft-shell crab transportation method. The method comprises the following steps: screening and cleaning, softening-keeping treatment, fresh-keeping treatment, microenvironment regulation and treatment after transportation. In the softening treatment, 0.1-3 PSU low-salt seawater containing 0.03%-0.08% of tetrasodium glutamate diacetate is used for soaking / covering, the fresh keeping is ethanol disinfection and 0.05%-0.30% of lemon grass oil emulsified spray, the temperature of the microenvironment is controlled to be 12-18 DEG C, the humidity is 85%-95%, and the oxygen content is 20.90-22.30%. After 72 hours of simulated transportation, the softness-keeping maintenance rate is greater than or equal to 88%, the survival rate is greater than or equal to 98%, the body surface bacterial colony inhibition rate is 91.4%, and the TVB-N value is 15.2 mg / 100g. The method realizes the synergy of softening, fresh keeping and live keeping, is suitable for large-scale transportation, and has high popularization value.
Owner:SOUTHERN MARINE SCIENCE & ENGINEERING GUANGDONG LABORATORY (ZHANJIANG)

Identity verification method and device, equipment, medium and product

The embodiment of the invention provides an identity verification method and device, equipment, a medium and a product, and relates to the field of biological recognition. The method comprises the following steps: acquiring multi-modal biological characteristic data of a user, and analyzing the multi-modal biological characteristic data through a living body detection technology; wherein the multi-modal biological characteristic data comprises a combination of at least two of the following biological characteristics: fingerprints, irises, voiceprints and facial images; according to the type of a service to be executed by the user, dynamically adjusting a priority strategy of biological feature verification; and generating an identity verification result based on the living body detection result and the priority strategy. According to the scheme of the invention, through combination of the multi-modal biological characteristic data and integration of a living body detection technology, diversity and anti-cheating capability of identity verification are enhanced, meanwhile, the dynamic priority strategy can be adaptively adjusted based on a service type, a verification process is optimized on the basis of improving verification safety, and thus reliability of identity verification is improved.
Owner:INDUSTRIAL AND COMMERCIAL BANK OF CHINA

Complete-set insulation baffle plate for replacing disconnecting link load side lead wire in 10kV live-line work and use method of complete-set insulation baffle plate

The invention belongs to the technical field of hot-line work, and particularly discloses a complete insulation baffle plate for replacing a disconnecting link load side lead in 10kV hot-line work and a use method, the complete insulation baffle plate comprises a hanging plate, and the hanging plate is of an insulated plane plate-shaped structure; the upper side edge and the lower side edge of the hanging plate are provided with a cross arm hook and a baffle handle respectively. The cross arm hook is used for being matched with a cross arm; one side surface of the hanging plate is provided with a disconnecting link inner side insulating cover; the carrying head baffle is arranged on the side of the hanging plate; the head carrying baffle is bent to be of a C-shaped structure, a second notch is formed in the bottom of the head carrying baffle, the second notch is provided with a disconnecting link outer side insulation cover, and the disconnecting link outer side insulation cover is matched with the disconnecting link inner side insulation cover and used for being matched with a disconnecting link. The disconnecting link shield is bent to be of a U-shaped structure; and the opening end of the disconnecting link shield is matched and connected with the bottom of the carrying head baffle plate. According to the invention, the electrified body and the grounding body can be effectively isolated, the structural stability in the operation process is improved, and the operation time and manpower consumption are reduced.
Owner:STATE GRID BEIJING ELECTRIC POWER CO

Application of salinomycin in preparation of medicine for resisting monkey pox virus infection

PendingCN121265586AOrganic active ingredientsAntiviralsDiseaseViral illness
The invention relates to the technical field of medicines, in particular to application of salinomycin in preparation of oral medicines for preventing or treating monkey pox virus (MPXV) infection. Salinomycin is a polyether antibiotic produced by actinomycetes. It is found for the first time that salinomycin can efficiently inhibit monkey pox virus infection on the cell culture level, and can significantly improve the survival rate of mice infected with monkey pox virus in small animal living bodies. More importantly, salinomycin can be administered by oral administration, has good bioavailability and safety, and provides a brand new treatment means for monkey pox virus infection. The medicinal value of salinomycin in resistance to monkey pox virus infection is reported for the first time at home and abroad, and the application prospect of salinomycin in the field of viral disease treatment is expanded.
Owner:THE NAVAL MEDICAL UNIV OF PLA

Method for extracting anticoagulant protein of leech

The invention discloses an extraction method of leech anticoagulant protein, and belongs to the technical field of biological extraction.According to the extraction method, after components of induction liquid are optimized, mucous membranes are activated, and the living tissue environment naturally sucked by leeches is simulated, so that the leeches can be induced to better suck, the sucking amount of the leeches is guaranteed, and the anti-coagulation protein content of the leeches is improved; the leeches can be effectively stimulated to secrete more anticoagulant proteins with higher activity; meanwhile, under the coordination effect of the tranquilizer, the leech is kept in a warm state, so that the silent and relaxed physiological state of the leech can still be ensured in a dizziness stimulation or air pressure difference stimulation state, the loss of the living leech can be reduced, conditions for repeated extraction are provided for the leech, the gland secretion activity of the leech tends to be stable and vigorous, and the survival rate of the leech is increased. The extraction rate is further improved.
Owner:FOSHAN AIDI BIOTECHNOLOGY CO LTD

Real-time monitoring method and system for life entity in automobile, electronic equipment and computer readable medium

PendingCN121697573AWindowsAir-treating devicesSimulationMild hypoxia
The invention provides a real-time monitoring method for life bodies in an automobile, and belongs to the field of intelligent driving. Data are collected through a sensing layer, intelligent analysis and risk assessment are carried out through a decision-making layer, finally, corresponding relieving and rescue measures are automatically executed through an execution layer, children / pets in sleep, coma and other non-moving states are reliably recognized, and the driving safety is improved. Multiple living bodies in the vehicle are distinguished and accurately positioned, the risk level (such as mild hypoxia vs endangered) is judged by fusing physiological and environmental data, a full-automatic closed loop of'detection-decision-rescue 'is realized, and manual response lag is avoided.
Owner:DONGFENG MOTOR GRP

Monitoring of endoleaks

A system including: an antenna configured to be implanted in a region a living body, wherein a frequency response and / or attenuation response of the antenna shifts in response to changes in a physiological condition of the living body at the region; an input / output module outside the living body and configured to actuate the antenna to generate a response signal and to receive the response signal, wherein the response signal indicates a frequency response and / or attenuation response of the antenna; and a processor configured to: detect whether the frequency response and / or attenuation response indicates a shift in the frequency and / or attenuation response of the antenna; and in response to the detection of the shift issue and / or record a notice that a change occurred in the physiological condition at the region inside the living body.
Owner:PERDIX ACCELERATOR LLC

Vehicle monitoring method and device based on multi-modal fusion perception

The invention discloses a vehicle monitoring method and device based on multi-modal fusion perception. The method comprises the steps that when it is monitored that a vehicle enters a locked state, the pressure change of a seat in the vehicle or the micro-motion characteristic of a detained object in the vehicle is collected; when the pressure change or the micro-motion feature meets an event triggering condition, triggering equipment in the vehicle to start, and collecting image feature information and audio feature information of the retained object; obtaining time-frequency spectrum feature information; processing the three kinds of information by using a feature fusion model to obtain joint reliability; when the joint reliability is higher than a reliability threshold, generating an emergency processing strategy; and according to the emergency processing strategy, the vehicle is triggered to conduct air exchange or ventilation operation. According to the invention, the technical problem of accidents caused by high temperature or oxygen deficit and the like in the vehicle due to the fact that a single sensing mode of a vehicle monitoring system in the related technology is difficult to effectively detect whether life bodies are retained in the vehicle in a vehicle locking state and an emergency processing strategy cannot be taken in time is solved.
Owner:GREE ELECTRIC APPLIANCE INC OF ZHUHAI +1

Method and system for detecting a bioanalyte in the blood

A microneedle device comprises a device structure, insertable to a living body and being formed with an opened niche at least partially surrounded by walls of micrometric heights above a base of the niche for allowing the niche to be filled with a blood sample upon the insertion. The device also comprises a biosensor configured to sense a bioanalyte in the blood sample and having a sensing element formed on the base. The thickness of the sensing element is less than the micrometric heights of the walls.
Owner:RAMOT AT TEL AVIV UNIVERSITY LTD

Targeted control method and system of drug-loaded nano robot

PendingCN121668530AMedical devicesMedical equipmentDrug availabilityExecution plan
The invention relates to the technical field of drug-loaded nano-robot control, and discloses a targeted control method and system for a drug-loaded nano-robot. The method comprises the following steps: building a task-resource matching model by receiving internal region division and treatment requirements of a living body and combining the performance and real-time position of a nano-robot; and according to the model, adopting a partition strategy to deploy the robot and optimize a control signal, and realizing accurate area distribution. And then planning a task time sequence of the treatment points, and analyzing intervals to formulate an execution plan. The matching degree of drug supply and robot endurance is evaluated, parameters are detected and adjusted to solve resource conflicts, and a steady drug delivery progress scheme is formed. And finally, executing the scheme, and dynamically regulating and controlling the instruction based on the real-time environment and state data. According to the method, fine scheduling and resource collaboration of the nano-robot cluster are realized, and the accuracy and efficiency of targeted drug delivery and the reliability of the treatment process are improved.
Owner:CHONGQING THREE GORGES UNIV

Nitric oxide fluorescent probe with aggregation-induced emission characteristic as well as preparation method and application of nitric oxide fluorescent probe

The invention provides a nitric oxide fluorescent probe with aggregation-induced emission characteristics and a preparation method and application thereof. The structural formula of the nitric oxide fluorescent probe is shown in the specification. The nitric oxide fluorescent probe provided by the invention is high in detection sensitivity, high in response speed, excellent in NO selectivity and AIE characteristic, wide in application range, not only suitable for liquid-phase and gas-phase NO detection, but also capable of realizing high-efficiency real-time detection of NO in body fluid, cells and living body samples, and wide in application prospect. The method can be used for diagnosis of diseases such as inflammation (rheumatoid arthritis), tumor microenvironment and the like, high-throughput drug screening and environment monitoring.
Owner:WUHAN UNIV OF TECH

Vision-based crab weight measuring system and method

The invention provides a crab weight measuring system and method based on vision, and the method comprises the steps: collecting an Eriocheir sinensis image on a measuring platform through a fixed camera, extracting a crab shell mask region based on a YOLOv8 image recognition technology, and calculating the pixel area of a target region; calculating a physical length corresponding to a unit pixel according to a reference object with a known size, and calculating an actual physical area of the crab carapace; meanwhile, the pixel width and length of the crab carapace are detected based on a key point detection algorithm, the thickness influence is corrected through a linear regression equation, the mapping relation between the pixel size and the actual physical size is established, and the actual carapace size of the crab is calculated; and then an improved TabTransform model is provided, and the obtained morphological characteristics of the crabs are used as data input, so that the weight of the crabs is measured. Therefore, the problems that in traditional aquaculture, manual measurement is low in efficiency and prone to causing stress injury to living bodies are solved, an automatic body weight measurement mode is provided, and high-precision and high-efficiency body weight measurement of crabs is achieved.
Owner:FUYANG NORMAL UNIVERSITY

Electric cooker voice safety control system and method based on voiceprint verification

The invention relates to the technical field of intelligent household electrical appliance control and biological characteristic recognition, and discloses an electric cooker voice safety control system and method based on voiceprint verification, the system comprises a multi-mode sensing array, a storage unit and a core processing unit, the method comprises the following steps: generating and storing equipment physical fingerprints representing unique physical characteristics of equipment, the method comprises the following steps: generating and storing a multi-dimensional feature template comprising an acoustic voiceprint, living body interaction and a spatial vector template for an authorized user, when a voice instruction is received, synchronously acquiring a to-be-detected acoustic and structural vibration signal by a system, executing layered collaborative authentication, and sequentially performing spatial domain verification, physical interaction verification and user identity verification, the physical interaction verification identifies the living body attribute of the sound source by comparing the real-time sound vibration coupling characteristic with the equipment physical fingerprint, so that the non-living body attack is effectively identified and intercepted, and the safety and reliability of voice control are improved.
Owner:LINGNAN NORMAL UNIV

Catheter assembly

A catheter assembly includes: an inner needle configured to puncture a living body; a catheter configured to allow the inner needle to be inserted therethrough; a catheter hub located at a proximal end of the catheter; a valve body located in an internal space of the catheter hub; an opening member located on a proximal side of the valve body, the opening member comprising: a cylindrical barrel portion, a neck portion extending from a distal end of the barrel portion, wherein a diameter of the neck portion is smaller than a diameter of the cylindrical barrel portion, and a foot portion extending to a proximal side of the barrel portion, wherein the opening member is configured to move in a distal direction to open the valve body; and a movement inhibiting mechanism that resists movement of the opening member in the distal direction via a contact portion.
Owner:TERUMO KK

Intelligent console identity verification method based on face recognition

The invention relates to the technical field of biological recognition and industrial control, and discloses an intelligent console identity verification method based on face recognition, which comprises the following steps: step 1, detecting candidate persons in a preset verification area through a millimeter wave radar; 2, responding to the detected candidate member, starting a near-infrared camera, collecting an eye circumference area image of the candidate member, and synchronously detecting the micro-motion feature of the candidate member by using the millimeter wave radar; and step 3, processing the collected eye circumference area image, performing local identity comparison, performing multi-channel living body detection in combination with the detected micro-motion characteristics, and granting an operation authority when the identity comparison is authorized and the living body detection is passed. A near-infrared camera is combined with a periocular feature comparison scheme, stable recognition under complex illumination and face shielding is achieved, and compared with a traditional visible light recognition scheme, the problem of verification failure caused by hard light, dark light and mask shielding is solved.
Owner:DALI CONSOLE (TIANJIN) CO LTD +1

Active oxygen concentration control method and brain-computer interface implant accelerated life test system

The invention relates to an active oxygen concentration control method and a brain-computer interface implant accelerated life test system. The accelerated life test system is used for testing the electrochemical performance of a brain-computer interface implant by using a test solution. The method comprises the following steps: detecting a current feedback current corresponding to a current test solution; obtaining the current active oxygen concentration according to the current feedback current and a preset active oxygen concentration and current relation function; generating a filling parameter according to a concentration difference value between the current active oxygen concentration and a preset active oxygen concentration; and adding a hydrogen peroxide solution into the current test solution according to the filling parameters, so that the current test solution reaches the preset active oxygen concentration. According to the method, the active oxygen environment generated by immune reaction in a living body can be simulated through the test solution, the active oxygen concentration in the test solution can be precisely regulated and controlled, and the accuracy of the test result of the brain-computer interface implant is improved.
Owner:SHANGHAI MEDICAL DEVICE INSPECTION & RES INST

Temperature-indicating label

PCT designated stageWO2026133673A1StampsFilm/foil adhesivesColored whiteChange color
This temperature-indicating label is provided with: a base material; an adhesive layer to be affixed to the surface of a living body; and a temperature-indicating ink layer that is positioned between the base material and the adhesive layer, and that is configured so as to change color in accordance with the temperature of the temperature-indicating ink layer. The stress at 20% stretching is 0.2 N / mm2 to 10.0 N / mm2. The thickness of the temperature-indicating ink layer is 1-9 µm. In a state in which the adhesive layer is affixed to a white plate, the color difference ΔE* ab in the L*a*b* color space between a first state in which the temperature-indicating ink layer exhibits a first color and a second state in which the temperature-indicating ink layer exhibits a second color different from the first color is greater than 10. The color change between the first color and the second color is visible via the base material.
Owner:TOPPAN HOLDINGS INC +1

Near-infrared two-region dual-channel fluorescent nanoprobe as well as preparation method and application thereof

The invention discloses a near-infrared two-region dual-channel fluorescent nanoprobe as well as a preparation method and application thereof, and relates to the technical field of biomedical imaging. A nano probe A and a nano probe B included in the near-infrared two-region dual-channel fluorescent nano probe are both of a core-shell structure, two NIR-IIb fluorescent nano probes adaptive to different excitation wavelengths (808 nm and 980 nm) are constructed by precisely regulating and controlling the types and proportions of lanthanide elements, dual-channel imaging is achieved, limitation of a single excitation wavelength is broken through, spectral crosstalk is eliminated, and the near-infrared two-region dual-channel fluorescent nano probe has the advantages of high sensitivity, high sensitivity, high sensitivity and the like. The method has the characteristics of material uniformity and biological safety. The near-infrared IIb region dual-channel imaging system has the characteristics of high temporal-spatial resolution and signal separation, and has significant application value in the field of living body multi-target synchronous observation. Compared with a traditional two-photon microscope technology, the imaging method has a wider observation view field, a local craniotomy operation does not need to be carried out on an experimental mouse, and physiological trauma is remarkably reduced.
Owner:INST OF BIOMEDICINE HENAN ACAD OF SCI

Pipeline line laying vehicle and line laying method

The invention discloses a pipeline laying vehicle and a laying method, and belongs to the technical field of communication construction. The invention aims to solve the problems of low laying efficiency, difficulty in positioning and poor environmental adaptability of wires in a pipeline in the prior art. The device provided by the invention adopts a cylindrical shell design, and a transmission system driven by double motors and an auxiliary system comprising a camera, a high beam and a loudspeaker are integrated in the device. The transmission system achieves synchronous rotation of wheels through a driving gear, a driven gear and a wheel fixing ring assembly, and the device can adapt to pipeline environments with different pipe diameters in cooperation with an elastic telescopic mechanism of a wheel support. The camera can monitor the environment in the pipeline in real time, the high beam is automatically triggered to illuminate according to light changes, and the loudspeaker is started to drive living organisms when the living organisms are detected. And the wire fixing nut frame is matched with the wire fixing bolt, so that the wire can be firmly fixed. According to the invention, automatic laying and accurate positioning of wires in the pipeline can be realized, the construction safety and efficiency are obviously improved, and the method is especially suitable for communication construction scenes in a narrow pipeline environment.
Owner:CHINA THREE GORGES UNIV

A neural network-based millimeter wave radar living body recognition method

The application discloses a kind of millimeter wave radar living body identification methods based on neural network, comprising: obtaining package original ADC data, signal pre-processing is carried out, and three-dimensional radar point cloud is generated;Three-dimensional radar point cloud is respectively subjected to space geometry feature enhancement and dynamics mode feature enhancement, and enhanced feature is obtained;Three-dimensional radar point cloud and enhanced feature are parallelly input into multimodal heterogeneous feature decoupling network, and the deep physical property feature of target is respectively decoupled and extracted;Cross-modal interaction and adaptive weighted fusion are carried out to the deep physical property feature, and obtain fusion feature vector;Fusion feature vector is input into classifier, and the discrimination result whether the target in package is living body is output.The deep physical property feature of target is extracted by the multimodal heterogeneous feature decoupling network of the application, and adaptive depth fusion is carried out using cross-modal attention mechanism, so as to effectively suppress non-living interference in complex dynamic environment, and the accuracy of living body detection is significantly improved.
Owner:CHINA JILIANG UNIV

Living body information measuring apparatus

A living body information measuring apparatus includes: an enclosure having an enclosure surface that comes into contact with an object under inspection in a measurement state in which living body information on the object under inspection is measured; a light measurement portion disposed in the enclosure and configured to radiate measurement light to the object under inspection and receive reflected light; and a light transmissive member configured to transmit the measurement light and the reflected light, having a contact surface that comes into contact with the object under inspection in the measurement state, and including at least one protrusion and a recess at least a part of which is surrounded by the at least one protrusion, the at least one protrusion and the recess being located at the contact surface.
Owner:SEIKO EPSON CORP

Enhancements for low-touch biometric systems

In various embodiments, enhancements for low-touch biometric systems include obtaining winnowing information when a biometric probe unsuccessfully matches against a subset gallery. The winnowing information is used to obtain biometric data from an associated group of people and the biometric probe is then compared against the biometric data. If this also fails, identity information may be obtained and used to obtain a corresponding biometric template to match the biometric probe against. In some embodiments, enhancements for low-touch biometric systems determining a dominant by selecting the largest live face in an image then performing one or more actions using the dominant. Such one or more actions may include selecting the dominant for capture, performing exposure control and / or gain control on the dominant as opposed to the rest of an image, determining guidance to provide for biometric capture based at least on a position of the dominant, providing such guidance, etc.
Owner:SECURE IDENTITY LLC

Visual micro-injection device for live cultivation of bovine gallstones

ActiveCN224685957Usimple procedureQuickly learn how to operateMinimal invasive surgeryGallstones
The utility model discloses a kind of visual microinvasive injectors for living body cultivation gall, belong to the technical field of pharmaceutical manufacturing.A kind of visual microinvasive injector for living body cultivation gall, including upper shell, lower shell, limit ring, sealing plate, bottom plate, sealing ring, buckles and support block, the upper shell is sleeved in the surface of lower shell and limit ring, the limit ring is sleeved in the surface of injector barrel, limit ring one end extends to the outside of upper shell, and the other end is penetrated to the inside of lower shell.The utility model is designed as integrally-formed injector, minimally invasive surgery and visualization technology are integrated, simplify surgical procedure, even non-professional technical personnel can quickly master operation method.Integrally-formed design reduces different tools needed to switch or use in cooperation in surgery, reduces surgery time, reduces operation complexity, improves surgery efficiency and safety.
Owner:KEHUA (SHENZHEN) DRUG RESEARCH & DEVELOPMENT CO LTD

Negative pressure isolation living body microscope experiment box

This invention provides a negative pressure isolation live microscope experimental box. The experimental box, through its closed negative pressure design, ensures the biosafety of experiments with pathogens of BSL-2 level and above, meeting the requirements of the safety committee review. At the same time, its innovative box-type integrated window structure eliminates the vibration torque caused by animal movement in traditional suspended windows from a mechanical design perspective, providing unparalleled stability for high-precision imaging. Ultimately, it makes it possible to safely and stably conduct live microscopic studies of highly pathogenic infection models in a conventional laboratory.
Owner:SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES

CXCL6-targeting blocking antibody and application thereof in preparation of antitumor drugs

The invention relates to the technical field of biological medicines, and discloses a blocking antibody targeting CXCL6 and an application of the blocking antibody in preparation of antitumor drugs. The antibody or antigen-binding fragment thereof is capable of binding specifically to human CXCL6 protein with high affinity (e.g., Kd < = 1 nM). According to the invention, the specificity and high affinity of the antibody are verified by Western Blot, immunofluorescence, immunohistochemistry and surface plasmon resonance (SPR) technologies. Functional experiments show that the antibody can effectively block CXCL6-induced neutrophil chemotaxis, including in Transwell, a three-dimensional gel model and a zebra fish living body model. Besides, in a mouse MC38 colon cancer model, the antibody shows remarkable anti-tumor activity and can inhibit tumor growth driven by CXCL6. The invention also provides a pharmaceutical composition containing the antibody, and application of the antibody in preparation of drugs for preventing or treating diseases (such as inflammatory diseases, autoimmune diseases and cancers) related to abnormal expression or activity of CXCL6.
Owner:AFFILIATED HOSPITAL OF JINING MEDICAL UNIV