1101results about "Transvascular endocardial electrodes" patented technology

A tool has an outer assembly, which includes a deployment tube, extending around, and moveable with respect to an inner assembly of the tool; the inner assembly includes a single pull wire and a distal member configured to engage an end of an implantable medical device. The deployment tube includes an articulating segment located just proximal to an enlarged distal-most portion, which contains the device and the distal member. Relatively soft and stiff sections of a composite sidewall define the articulating segment and extend alongside one another, such that, when the pull wire is actuated, the composite sidewall causes bending of the segment in two directions. A handle assembly of the tool includes a control member for the pull wire, and may further include a flushing subassembly that has a connector port located at an end of the handle assembly that is opposite a proximal port of the handle.

Aspects of the present disclosure relate to flexible catheters for electrophysiological mapping and ablation using high-density electrode arrays. These catheters can be used to detect the electrophysiological properties of tissue in contact with the electrodes and perform monopolar and bipolar ablation of the tissue.

A catheter and method for detecting dyssynergy resulting from dyssynchrony There is provided a catheter for assessing cardiac function, the catheter comprising an elongate shaft extending from a proximal end to a distal end, where the shaft comprises a lumen for a guidewire and / or a saline flush. The catheter further comprises at least one electrode disposed on the shaft for sensing electrical signals in a bipolar or unipolar fashion and applying pacing to a patient's heart, at least one sensor disposed on the shaft for detecting an event relating to the rapid increase in the rate of pressure increase within the left ventricle of a patient; and communication means configured to transmit data received from the electrode(s) and the sensor(s).

Devices, systems, and methods for generating therapy annotations for display on a graphical user interface are disclosed herein. In some embodiments, therapy annotations can correspond to a location of a tip section of a catheter relative to an anatomical structure of a patient when therapy is delivered to the anatomical structure. One or more properties of the therapy annotations can be based at least in part on signals received from sensors distributed about the tip section of the catheter and / or on other characteristics of therapy delivery. The therapy annotations can be displayed alone or in combination with a three-dimensional surface representation of the anatomical structure, a representation of the catheter, and / or other visual indicia, such as a therapy contour, a distance from a nearest therapy site and / or the most recent therapy site, and / or a representation of gaps between two therapy sites.

A separable sheath for an implantable medical device may include a shell having an outer diameter and an inner diameter. A lumen may be defined by an inner diameter and extend from a proximal end to a distal end of the shell. The electrode may be located at a distal end of the sheath. A signal line may be disposed within the housing and electrically coupled to the electrode. The guide rail may be configured to shield the signal line from a cutting path of the sheath separator. In some examples, the sheath may also include a second rail. For example, the signal line may be located between the first rail and the second rail along the length of the sheath. The cutting path may be located between the first rail and the second rail on a side of the sheath radially opposite the signal line.

An example catheter includes a handle assembly having a control member, an elongated body, a pull wire, and at least one radiopaque marker. The elongated body defines a lumen configured to receive a medical electrical lead comprising at least one electrode array. The elongated body includes a proximal portion and a distal portion, the proximal portion being coupled to the handle assembly, the distal portion including an articulation segment and a preformed curved segment. The at least one radiopaque marker is positioned on the distal portion. The pull wire extends from the control member and is anchored to the elongated body distal to the articulation segment, such that actuation of the control member causes the articulation segment to be controllably bend along a first curve in a first geometric plane. The preformed curved segment defines a second curve in a second geometric plane different from the first geometric plane.

A prosthetic cardiac valve includes a frame and plurality of prosthetic leaflets coupled to the frame so as to allow blood flow in one direction. An antenna is mechanically coupled to the frame, and includes a magnetic core and one or more coils wound about the magnetic core. At at least one location along a length of the magnetic core, a planar space bound by an outer perimeter of the magnetic core, in a plane perpendicular to a central longitudinal axis of the frame, has (a) a shorter dimension, which is measured along a ray that radiates radially outward from the central longitudinal axis and intersects a centroid defined by the planar space, and (b) a longer dimension, which is measured perpendicular to the shorter dimension in the plane, and is at least 150% of the shorter dimension. Other embodiments are also described.

The present invention includes systems, devices and methods for treating and / or diagnosing a heart arrhythmia, such as atrial fibrillation. Specifically, the present invention provides a system including a diagnostic catheter and an ablation catheter. The diagnostic catheter includes a shaft, multiple dipole mapping electrodes and multiple ultrasound transducers. The ablation catheter is slidingly received by the diagnostic catheter shaft.

A prosthetic cardiac valve (620) includes a frame (630) and a plurality of prosthetic leaflets (32) coupled to the frame (630) so as to allow blood flow in one direction. An antenna (28) is mechanically coupled to the frame (630) proximal of the prosthetic leaflets, and includes one or more prosthetic-valve coils (36). First and second proximal peaks (204 A, 204B) respectively defined by circumferentially adjacent first and second proximal- most stent cells (206A, 206B) of interconnected stent cells (192) of the frame (630) are located at respective first and second peak angular locations (208 A, 208B) about a central longitudinal axis (60) of the frame (630). The antenna (28) is mechanically coupled to the frame (630) such that a centroid (212) of the antenna (28) is at an antenna angular location (214) between the first and the second peak angular locations (208A, 208B), and a proximal-most point (216) of the antenna (28) is axially disposed between 5 mm proximal of and 5 mm distal of the first and the second proximal peaks (204 A, 204B). Other embodiments are also described.

A system comprises processing circuitry and memory comprising program instructions that, when executed by the processing circuitry, cause the processing circuitry to: apply a first set of rules to first patient parameter data for a first determination of whether sudden cardiac arrest of a patient is detected; determine that a one or more context criteria of the first determination are satisfied; and in response to satisfaction of the context criteria, apply a second set of rules to second patient parameter data for a second determination of whether sudden cardiac arrest of the patient is detected. At least the second set of rules comprises a machine learning model, and the second patient parameter data comprises at least one patient parameter that is not included in the first patient parameter data.

Methods, apparatuses, and systems for performing a valve replacement or repair. Apparatuses may include systems and may include an outer catheter, one or more interchangeable inner catheters, a guidewire and an expandable chordae tendinae deflector. Also described herein are rapid pacing sheaths that may be used with any of these apparatuses and methods.

The invention discloses a leadless pacemaker for pace-making in a left bundle branch area and a delivery sheathing canal thereof.The leadless pacemaker comprises a pacemaker body, the center of the pacemaker body is partially provided with a first internal thread section, and a pacemaker electrode is partially provided with a first external thread section; the first internal thread section and the first external thread section are matched and screwed, so that the pacemaker electrode can be controlled to extend or retract by rotating the pacemaker electrode; when the pacemaker is used, the front end of the pacemaker body is flush with the front end of the shell, and the front end of the pacemaker electrode and the electrode spiral structure of the pacemaker electrode extend out of the pacemaker body by the maximum distance of 10 mm. The device can be safely and effectively implanted into the left bundle branch area, is stable for a long time and cannot be fractured or dislocated, and pace-making of the left bundle branch area is achieved.

A medical lead includes a lead body, a lead body helix extending from a distal end of the lead body, wherein the lead body helix is configured to anchor to a patient tissue, and, a cable within the lead body, the cable including a cable conductor, a cable electrode proximate a distal end of the cable conductor, and a cable helix with a blunt tip at a distal end of the cable. The cable is slidable within the lead body to extend and retract the cable electrode along a trajectory extending from the distal end of the lead body.

A urinary dysfunction treatment apparatus is provided. The apparatus comprises an implantable constriction device configured to constrict at least one portion of the tissue wall of a patient's urethra to at least restrict the flow of urine, an operation device for operating the constriction device to change the constriction of the urethra, a control unit for controlling the operation device, wherein the control unit is configured to: control the operation device to constrict the urethra, and control the operation device to release the urethra, and a source of energy for supplying energy to the operation device. The control unit is configured to determine a current state of the source of energy, and wherein the control unit is connected to an internal signal transmitter configured to transmit information related to the current state of the source of energy.

The invention provides devices and systems that help deliver agents of interest, such as therapeutic agents (e.g., nucleic acid vectors) to cells of hollow tissues, such as lung. Also provided herein are methods of using such devices, including methods of treating diseases by delivering therapeutic agents to hollow tissues.

A system for personalized neuromodulation includes a neuroimaging recording device including sensors for detecting neural activity in a patient. An optimization module determines a personalized neuromodulation treatment protocol for the patient. The optimization module includes a neuromodulation target optimization module for determining neural targets in the patient for the personalized neuromodulation treatment protocol. The optimization module includes a neuromodulation parameters optimization module for determining optimized neural stimulation parameters for the personalized neuromodulation treatment protocol. A personalized neural stimulation device receives the neural targets from the neuromodulation target optimization module and receives the optimized neural stimulation parameters from the neuromodulation parameters optimization module. The personalized neural stimulation device delivers the personalized neuromodulation treatment protocol to the patient. The personalized neural stimulation device includes at least one neural stimulation device for stimulating the targets in the patient. A neuroimaging navigation system determines a placement of the neural stimulation device(s) about the patient.

A biostimulator includes a body having an electronics compartment containing pacing circuitry. The biostimulator includes an electrode arm pivotably coupled to the body. The electrode arm is pivotable from an undeployed state to a deployed state. A pivot angle between the electrode arm and the body is greater in the deployed state than in the undeployed state. Other embodiments are also described and claimed.

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

A method of delivering a pacing lead may include locating a potential implantation site adjacent to or within the triangle of Koch region of a patient's heart. The method may include advancing a pacing lead to the potential implantation site. The pacing lead has an elongate body and a fixation element coupled to a distal portion and attachable to the right-atrial endocardium adjacent to or within the triangle of Koch region. The method may include implanting the pacing lead at the potential implantation site to or sense electrical activity of the left ventricle in the basal and / or septal region of the left ventricular myocardium of the patient's heart. The pacing lead may include a lumen configured to receive a guide wire. A sheath of a delivery system used to deliver the pacing lead may include two or more curves to facilitate implanting the pacing lead at the implantation site.

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

In some examples, an endovascular medical device system includes an elongated body configured to be introduced in a blood vessel of a patient. The system includes an expandable structure at a distal portion of the elongated body. The expandable structure includes an expandable body portion including a plurality of interconnected struts. The expandable structure further includes a plurality of electrode attachment elements, where each electrode attachment element of the plurality of electrode attachment elements includes a first projection and a second projection branching off of at least one strut of the plurality of interconnected struts. In some examples, the system includes one or more electrodes coupled to the expandable structure via the plurality of electrode attachment elements. In some examples, each electrode of the one or more electrodes is configured to receive the first projection and the second projection to couple the respective electrode to the expandable structure.

An implant delivery system, a cardiac rhythm adjustment system, and a cardiac rhythm adjustment method. The implant delivery system comprises a puncture sheath (20) and an implant. The puncture sheath (20) comprises a hollow tube body (12). The implant is releasably disposed in the tube body (12), a distal end of the tube body (12) is a puncture head (13) which can pierce into the ventricular muscle and guide the tube body (12) to pass through the ventricular muscle, and the length of the tube body (12) at least is able to extend into the ventricular muscle from the outside via the apex (4). The implant is an implantable electrode (60, 61, 62, 63, 64, 65, 66), and implantation via an intramyocardial route is used for the electrode (60, 61, 62, 63, 64, 65, 66), so as to achieve real physiological position pacing and biventricular electrical synchronization by means of program control of a pulse generator (80).

The embodiments described herein relate to a self-positioning, quick-deployment low profile transvenous electrode system for sequentially pacing both the atrium and ventricle of the heart in the "dual chamber" mode having an atraumatic tip comprising a domed head connected to a cylindrical sidewall, said cylindrical sidewall having a sloped proximal edge connected to a tapered coupling, said tapered coupling forming a smooth transition to an outer diameter of the insulated wire, and methods for deploying the same.

The invention relates to the use of an electronic element (E) with at least one processor—and memory function (27b), for use as an arithmetic element (6) and / or computer element (6) and / or device element (2a) and / or component element (2a), the electronic element comprising an identification—(1c) and / or authentication function (1c) of a user in a digital network (12) by means of a computer-assisted, at least partly automated and / or autonomously ordered encrypted method (14e), and / or comprising a computer-assisted, at least partly automated and / or autonomously ordered control function (1b), wherein the electronic element (E) consists of at least one hardware element (27) and / or software (26).

A composite wire suitable for use as a pacing or biostimulation lead has improved durability when compared to currently available materials. Specifically, a lead includes a superelastic wire including, e.g., nitinol. The wire is coated with polyimide and subsequently wound into a strand, cable, coil, or helically stranded tube. This wound structure is thermomechanically treated to shape-set the wire construct and retain a desired wound and shaped configuration, without adversely affecting the integrity of the polyimide coating.

The invention belongs to the technical field of medical instruments, and particularly relates to a rotating tail wire and an operation method thereof.According to the rotating tail wire and the operation method, by arranging a sliding ring rotating cylinder, a conductive wire assembly and an electrode interface assembly, knotting and winding at the tail wire are prevented, uninterrupted work is achieved, and the service life of the rotating tail wire is prolonged. And the working efficiency and the stability of current and resistance during working are ensured.

A biostimulator and a biostimulator system for septal pacing are described. The biostimulator includes a housing having an electronics compartment containing pacing circuitry and an electrical extension having an elongated electrical conductor, wherein the electrical extension extends from a proximal extension end at the housing to a distal extension end. The biostimulator further includes a pacing extension body mounted on the distal extension end of the electrical extension. The pacing extension body includes a pacing electrode electrically coupled to the pacing circuitry through the elongated electrical conductor, a fixation mechanism, and a drive mechanism to transmit torque to the fixation mechanism. Other embodiments are also described and claimed.

The present disclosure provides electroporation systems and methods of energizing a catheter for delivering electroporation. A catheter for delivering electroporation includes a distal section and an electrode assembly. The distal section is configured to be positioned in a vein within a body. The vein defines a central axis. The electrode assembly is coupled to the distal section and includes a structure and a plurality of electrodes distributed thereabout. The structure is configured to at least partially contact the vein. Each of the electrodes is configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein.

A delivery system and method are described that include a catheter and an active wire. The catheter has a catheter body that defines a primary lumen and a secondary lumen therethrough, which are spaced apart from each other. A distal end of the catheter body is configured to be located within a chamber of a heart proximate to myocardial tissue at a site of interest (SOI). The primary lumen has a greater cross-sectional size than the secondary lumen. The primary lumen is configured to receive at least a portion of an IMD therein and to permit the portion of the IMD to move relative to the catheter. The active wire is configured to extend through the secondary lumen so that a distal end of the active wire projects beyond the distal end of the catheter body to pierce the myocardial tissue at the SOI.

A delivery catheter for delivering a pacemaker lead into cardiac tissue. The catheter includes a distal end with a tip having an electrode configured for unipolar ablation of cardiac tissue that provides a breach of the endocardium while minimizing trauma to the patient.