747results about "Transvascular endocardial electrodes" patented technology

Aspects of the present disclosure relate to flexible catheters for electrophysiological mapping and ablation using high-density electrode arrays. These catheters can be used to detect the electrophysiological properties of tissue in contact with the electrodes and perform monopolar and bipolar ablation of the tissue.

Devices, systems, and methods for generating therapy annotations for display on a graphical user interface are disclosed herein. In some embodiments, therapy annotations can correspond to a location of a tip section of a catheter relative to an anatomical structure of a patient when therapy is delivered to the anatomical structure. One or more properties of the therapy annotations can be based at least in part on signals received from sensors distributed about the tip section of the catheter and / or on other characteristics of therapy delivery. The therapy annotations can be displayed alone or in combination with a three-dimensional surface representation of the anatomical structure, a representation of the catheter, and / or other visual indicia, such as a therapy contour, a distance from a nearest therapy site and / or the most recent therapy site, and / or a representation of gaps between two therapy sites.

A separable sheath for an implantable medical device may include a shell having an outer diameter and an inner diameter. A lumen may be defined by an inner diameter and extend from a proximal end to a distal end of the shell. The electrode may be located at a distal end of the sheath. A signal line may be disposed within the housing and electrically coupled to the electrode. The guide rail may be configured to shield the signal line from a cutting path of the sheath separator. In some examples, the sheath may also include a second rail. For example, the signal line may be located between the first rail and the second rail along the length of the sheath. The cutting path may be located between the first rail and the second rail on a side of the sheath radially opposite the signal line.

The present invention includes systems, devices and methods for treating and / or diagnosing a heart arrhythmia, such as atrial fibrillation. Specifically, the present invention provides a system including a diagnostic catheter and an ablation catheter. The diagnostic catheter includes a shaft, multiple dipole mapping electrodes and multiple ultrasound transducers. The ablation catheter is slidingly received by the diagnostic catheter shaft.

A prosthetic cardiac valve (620) includes a frame (630) and a plurality of prosthetic leaflets (32) coupled to the frame (630) so as to allow blood flow in one direction. An antenna (28) is mechanically coupled to the frame (630) proximal of the prosthetic leaflets, and includes one or more prosthetic-valve coils (36). First and second proximal peaks (204 A, 204B) respectively defined by circumferentially adjacent first and second proximal- most stent cells (206A, 206B) of interconnected stent cells (192) of the frame (630) are located at respective first and second peak angular locations (208 A, 208B) about a central longitudinal axis (60) of the frame (630). The antenna (28) is mechanically coupled to the frame (630) such that a centroid (212) of the antenna (28) is at an antenna angular location (214) between the first and the second peak angular locations (208A, 208B), and a proximal-most point (216) of the antenna (28) is axially disposed between 5 mm proximal of and 5 mm distal of the first and the second proximal peaks (204 A, 204B). Other embodiments are also described.

The invention discloses a leadless pacemaker for pace-making in a left bundle branch area and a delivery sheathing canal thereof.The leadless pacemaker comprises a pacemaker body, the center of the pacemaker body is partially provided with a first internal thread section, and a pacemaker electrode is partially provided with a first external thread section; the first internal thread section and the first external thread section are matched and screwed, so that the pacemaker electrode can be controlled to extend or retract by rotating the pacemaker electrode; when the pacemaker is used, the front end of the pacemaker body is flush with the front end of the shell, and the front end of the pacemaker electrode and the electrode spiral structure of the pacemaker electrode extend out of the pacemaker body by the maximum distance of 10 mm. The device can be safely and effectively implanted into the left bundle branch area, is stable for a long time and cannot be fractured or dislocated, and pace-making of the left bundle branch area is achieved.

A medical lead includes a lead body, a lead body helix extending from a distal end of the lead body, wherein the lead body helix is configured to anchor to a patient tissue, and, a cable within the lead body, the cable including a cable conductor, a cable electrode proximate a distal end of the cable conductor, and a cable helix with a blunt tip at a distal end of the cable. The cable is slidable within the lead body to extend and retract the cable electrode along a trajectory extending from the distal end of the lead body.

A system for personalized neuromodulation includes a neuroimaging recording device including sensors for detecting neural activity in a patient. An optimization module determines a personalized neuromodulation treatment protocol for the patient. The optimization module includes a neuromodulation target optimization module for determining neural targets in the patient for the personalized neuromodulation treatment protocol. The optimization module includes a neuromodulation parameters optimization module for determining optimized neural stimulation parameters for the personalized neuromodulation treatment protocol. A personalized neural stimulation device receives the neural targets from the neuromodulation target optimization module and receives the optimized neural stimulation parameters from the neuromodulation parameters optimization module. The personalized neural stimulation device delivers the personalized neuromodulation treatment protocol to the patient. The personalized neural stimulation device includes at least one neural stimulation device for stimulating the targets in the patient. A neuroimaging navigation system determines a placement of the neural stimulation device(s) about the patient.

A biostimulator includes a body having an electronics compartment containing pacing circuitry. The biostimulator includes an electrode arm pivotably coupled to the body. The electrode arm is pivotable from an undeployed state to a deployed state. A pivot angle between the electrode arm and the body is greater in the deployed state than in the undeployed state. Other embodiments are also described and claimed.

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

A method of delivering a pacing lead may include locating a potential implantation site adjacent to or within the triangle of Koch region of a patient's heart. The method may include advancing a pacing lead to the potential implantation site. The pacing lead has an elongate body and a fixation element coupled to a distal portion and attachable to the right-atrial endocardium adjacent to or within the triangle of Koch region. The method may include implanting the pacing lead at the potential implantation site to or sense electrical activity of the left ventricle in the basal and / or septal region of the left ventricular myocardium of the patient's heart. The pacing lead may include a lumen configured to receive a guide wire. A sheath of a delivery system used to deliver the pacing lead may include two or more curves to facilitate implanting the pacing lead at the implantation site.

An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative cuff body configured to be circumferentially disposed around a nerve, first and second relatively wide electrically conductive contacts carried by the cuff body that are spaced from one another in the length direction and that extend in the width direction to such an extent that they extend completely around the cuff body inner lumen when the cuff body is in the pre-set furled shape, and a plurality of relatively narrow electrically conductive contacts carried by the cuff body that are spaced from one another in the width direction and are located between the first and second relatively wide electrically conductive contacts.

An implant delivery system, a cardiac rhythm adjustment system, and a cardiac rhythm adjustment method. The implant delivery system comprises a puncture sheath (20) and an implant. The puncture sheath (20) comprises a hollow tube body (12). The implant is releasably disposed in the tube body (12), a distal end of the tube body (12) is a puncture head (13) which can pierce into the ventricular muscle and guide the tube body (12) to pass through the ventricular muscle, and the length of the tube body (12) at least is able to extend into the ventricular muscle from the outside via the apex (4). The implant is an implantable electrode (60, 61, 62, 63, 64, 65, 66), and implantation via an intramyocardial route is used for the electrode (60, 61, 62, 63, 64, 65, 66), so as to achieve real physiological position pacing and biventricular electrical synchronization by means of program control of a pulse generator (80).

The invention relates to the use of an electronic element (E) with at least one processor—and memory function (27b), for use as an arithmetic element (6) and / or computer element (6) and / or device element (2a) and / or component element (2a), the electronic element comprising an identification—(1c) and / or authentication function (1c) of a user in a digital network (12) by means of a computer-assisted, at least partly automated and / or autonomously ordered encrypted method (14e), and / or comprising a computer-assisted, at least partly automated and / or autonomously ordered control function (1b), wherein the electronic element (E) consists of at least one hardware element (27) and / or software (26).

A composite wire suitable for use as a pacing or biostimulation lead has improved durability when compared to currently available materials. Specifically, a lead includes a superelastic wire including, e.g., nitinol. The wire is coated with polyimide and subsequently wound into a strand, cable, coil, or helically stranded tube. This wound structure is thermomechanically treated to shape-set the wire construct and retain a desired wound and shaped configuration, without adversely affecting the integrity of the polyimide coating.

A delivery system and method are described that include a catheter and an active wire. The catheter has a catheter body that defines a primary lumen and a secondary lumen therethrough, which are spaced apart from each other. A distal end of the catheter body is configured to be located within a chamber of a heart proximate to myocardial tissue at a site of interest (SOI). The primary lumen has a greater cross-sectional size than the secondary lumen. The primary lumen is configured to receive at least a portion of an IMD therein and to permit the portion of the IMD to move relative to the catheter. The active wire is configured to extend through the secondary lumen so that a distal end of the active wire projects beyond the distal end of the catheter body to pierce the myocardial tissue at the SOI.

A delivery catheter for delivering a pacemaker lead into cardiac tissue. The catheter includes a distal end with a tip having an electrode configured for unipolar ablation of cardiac tissue that provides a breach of the endocardium while minimizing trauma to the patient.

Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

A valve bypass tool, and a biostimulator transport system having such a valve bypass tool, is described. The valve bypass tool includes an annular seal to seal against a protective sheath of the biostimulator transport system. The valve bypass tool is slidably mounted on the protective sheath and includes a bypass sheath to insert into an access introducer. The valve bypass tool can lock onto the access introducer by mating a locking tab of the valve bypass tool with a locking groove of the access introducer. The locking tab can have a detent that securely fastens the components to resist decoupling when the biostimulator transport system is advanced through the access introducer into a patient anatomy. Other embodiments are also described and claimed.

A system for extracting a transvenous endocardial lead includes a lead extender with a collet configured to releasably engage a pin of a connector on the lead, and a locking ring configured to maintain the engagement of the collet on the pin of the connector. The system further includes a lead extraction sheath having a sheath body with a tapered distal region, wherein a wall of the tapered distal region and a wall of the sheath body include an arrangement of openings configured to allow insertion of the lead extender and a body of the endocardial lead.

Systems, devices, and methods for promoting a patient's volume return to the heart and cardiac pre-load by inducing constriction of at least a portion of the splanchnic bed of the patient are described herein. Constriction of at least a portion of the splanchnic bed is induced via electrical stimulation to splanchnic nerve fibers of one or more splanchnic nerves. Electrical stimulation to splanchnic nerve fibers is delivered using at least one intravenous electrode disposed within a vein of the patient proximate to the splanchnic nerve fibers.

Embodiments herein relate to implantable systems and methods for treatment of pancreatic cancer. In an embodiment, a method of treating pancreatic cancer is included, the method including inserting an electrical stimulation lead through the inferior vena cava, a hepatic vein, and into the portal vein via a transjugular intrahepatic portosystem shunt (TIPS). The method can further include inserting the electrical stimulation lead into at least one of the superior mesenteric vein and the splenic vein. The method can further include positioning electrodes on the lead within at least one of the superior mesenteric vein and the splenic vein and delivering one or more electric fields through the electrodes to a treatment zone including at least a portion of the pancreas. The electric fields can be at frequencies and a field strength effective to prevent and / or disrupt cellular mitosis in a cell.

A biostimulator and a biostimulator system for septal pacing, is described. The biostimulator includes an articulation to allow an electrode axis of a pacing electrode to be directed differently than a housing axis of a housing. The housing contains electrical circuitry that is electrically connected to the pacing electrode. The differently directed axes allow the pacing electrode to affix to target tissue of an interventricular septal wall of a heart when the housing of the biostimulator is located near an apex of the heart. The articulation can include a flexible portion of an extension, a hinge, or a tether. Other embodiments are also described and claimed.

A method and system is presented for an implantable wireless power receiver for use with a medical stimulation or monitoring device. The receiver receives transmitted energy through one or more non-inductive antenna(s), utilizes microelectronics to perform rectification of the received signal for generation of a DC power supply to power an implantable device, and may also utilize microelectronics to provide parameter settings to the device, or stimulating or other waveforms to a tissue.

Methods, apparatuses, and systems for performing a valve replacement or repair. Apparatuses may include systems and may include an outer catheter, one or more interchangeable inner catheters, a guidewire and an expandable chordae tendinae deflector. Also described herein are rapid pacing sheaths that may be used with any of these apparatuses and methods.

Intra-cardiac voltage data display systems display a plurality of data sets derived at least from intra-cardiac voltage data sampled by an electrode. In some embodiments, at least some of the data sets are derived from a portion of the intra-cardiac voltage data that excludes an excludable portion of the intra-cardiac voltage data having a relationship with an occurrence of a particular cardiac event to facilitate identification of the existence of a transmural lesion in tissue adjacent the electrode. In some embodiments, the particular cardiac event is the occurrence of an R wave in the cardiac cycle, and the excludable portion is a V wave in the cardiac cycle.