330 results about "Implantation Site" patented technology

The present invention relates to a stent (10) for the positioning and anchoring of a valvular prosthesis (100) in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and / or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis (100) fastened to a stent (10) will occur relative the stent (10) in the implanted state of the stent (10), even given the peristaltic motion of the heart, the stent (10) according to the invention comprises at least one fastening portion (11) via which the valvular prosthesis (100) is connectable to the stent (10). The stent (10) further comprises positioning arches (15) and retaining arches (16), whereby at least one positioning arch (15) is connected to at least one retaining arch (16) via a first connecting land (17). The stent (10) moreover comprises at least one auxiliary retaining arch (18) which connects the respective arms (16′, 16″) of the at least one retaining arch (16) connected to the at least one positioning arch (15).

Compliance control stitch patterns sewn or embroidered into biotextile or medical textile substrates impart reinforcing strength, and stretch resistance and control into such substrates. Compliance control stitch patterns may be customizable to particular patients, substrate implantation sites, particular degenerative or diseased conditions, or desired time frames. Substrates having compliance control stitch patterns sewn or embroidered into them may be used in tissue repair or tissue reconstruction applications.

The invention relates to the field of medical physics, and discloses a control method and system for pulse electric field ablation of duodenum, and the method comprises the steps: determining a multi-target tissue, needing pulse electric field ablation, of the duodenum corresponding to a target user, collecting a target tissue image of the multi-target tissue, and constructing a multi-tissue three-dimensional model of the multi-target tissue; analyzing tissue parameters of the multi-target tissue, and analyzing electric field intensity and pulse parameters required for ablation of the multi-target tissue; multiple electrodes of the ablation equipment are configured, and multiple electrode implantation sites of the multiple electrodes are determined; constructing a digestive tract model from the corresponding oral cavity to the duodenum of a target user, analyzing an ideal transmission path of multiple electrodes, analyzing a path deviation coefficient of a simulation transmission path and the ideal transmission path, correcting the simulation transmission path, transmitting the multiple electrodes to a multi-electrode implantation site, and then performing multi-electrode implantation. And pulse electric field ablation of multi-target tissues is realized by utilizing multiple electrodes. The precise ablation effect of the pulsed electric field can be improved.

A prosthetic heart valve is designed to be circumferentially collapsible for less invasive delivery into the patient. At the implant site the valve re-expands to a larger circumferential size, i.e., the size that it has for operation as a replacement for one of the patient's native heart valves. The valve includes structures that, at the implant site, extend radially outwardly to engage tissue structures above and below the native heart valve annulus. These radially outwardly extending structures clamp the native tissue between them and thereby help to anchor the prosthetic valve at the desired location in the patient.

Apparatuses, systems, and methods for various devices, such as prosthetic valves. Some examples are directed to improvements in anchoring at a native heart valve, which may reduce possible trauma to a treatment or implantation site. Compliant and flexible anchoring features and methods are disclosed to reduce force upon a treatment or implantation site including heart tissue that surrounds leaflets of a mitral or tricuspid valve. Improved mechanisms for deployment of devices including motorized methods are also disclosed.

Devices, systems and methods deliver implantable medical devices for atrioventricular (VfA) cardiac treatment. The VfA device can be implanted in the right atrium (RA), where electrodes extend from the right atrium into the left ventricular myocardium. A flexible lead or other probe can be advanced to a potential implantation site and used to identify the precise location of an implanted medical device, such as an electrode, a small lead, a lead, or an intracardiac device. Some methods may include locating a potential implantation site in the Koch triangle in the right atrium of the patient's heart; attaching a retaining sheath to the right atrial endocardium of the potential implantation site; and implanting the medical device via a guidewire at the potential implantation site. An implantable medical device may include an intracardiac housing and a small lead that can be delivered by these methods.

The invention provides a photoacoustic microimaging brain electrode implantation site and path planning method and system, and the method comprises the steps: an image extraction step: employing a brain blood vessel enhanced extraction algorithm to extract an input photoacoustic microscanning imaging result, and obtaining brain blood vessel information; the cerebrovascular information comprises two-dimensional image information and a three-dimensional reconstruction result of the cerebrovascular; and an implantation site and path acquisition step: processing the cerebrovascular information by using a brain electrode implantation site path planning algorithm to obtain an implantation site on the two-dimensional image and an implantation path in the three-dimensional structure. According to the invention, the brain blood vessel enhanced extraction algorithm is adopted, so that the problems of high photoacoustic scanning imaging noise and poor imaging quality are solved, and accurate extraction and three-dimensional reconstruction of the brain blood vessel are realized.

Apparatuses, systems, and methods for prosthetic valves. An implantation site may comprise a native heart valve or another implantation site in examples. Examples may be utilized for improved anchoring and sealing of flow (e.g., paravalvular leakage) with a native heart valve having calcification. Examples may include breaking up calcification of a native heart valve to improve deployment to the native heart valve.

The present invention provides a bioabsorbable photocurable composition, a bioabsorbable tissue regeneration inducing material including the same, and a transplantation method using the same. The bioabsorbable photocurable composition includes a photoreduction agent and collagen, and is applied to the top of a transplantation site filled with a transplantation material, filling the empty space at the transplantation site and covering the transplantation material. The photoreduction agent is activated by irradiation with visible light to crosslink the collagen, and the collagen crosslinked by the visible light fills the minute empty space at the transplantation site and tightly bonds with the transplantation material to fix the transplantation material.

The invention discloses a composite material, a preparation method thereof and an implant, and belongs to the technical field of medical materials. The composite material is obtained by compounding a piezoelectric material and a metal ion release material, the metal ion release material is selected from one or more of magnesium-based degradable alloy, iron and iron-based degradable alloy, and zinc and zinc-based degradable alloy. The composite material can adaptively generate micro-currents with different magnitudes at different recovery stages of a patient through piezoelectric response of a piezoelectric material, and the micro-currents promote intelligent degradation, matched with self-recovery of the patient, of a metal ion release material. And the metal ions obtained by degradation and the micro current jointly promote the healing of the implanted part, which is of great significance to the development and application of implant materials.

A pharmaceutical composition according to an aspect can be applied to the prevention, treatment or the like of endometrial damage, Asherman's syndrome, or complications thereof by: reducing the level of collagen accumulation in the endometrium; increasing the expression level of VEGF; increasing the expression level of Ki67; increasing the expression level of Itgb3; increasing the expression level of Spp1; increasing the number of implantation sites; decreasing the expression levels of fibrosis-related factors; decreasing the expression levels of metabolism-related factors; increasing ATP production; and regulating the expression levels of mitochondrial function-related factors.

A method of delivering a pacing lead may include locating a potential implantation site adjacent to or within the triangle of Koch region of a patient's heart. The method may include advancing a pacing lead to the potential implantation site. The pacing lead has an elongate body and a fixation element coupled to a distal portion and attachable to the right-atrial endocardium adjacent to or within the triangle of Koch region. The method may include implanting the pacing lead at the potential implantation site to or sense electrical activity of the left ventricle in the basal and / or septal region of the left ventricular myocardium of the patient's heart. The pacing lead may include a lumen configured to receive a guide wire. A sheath of a delivery system used to deliver the pacing lead may include two or more curves to facilitate implanting the pacing lead at the implantation site.

The invention relates to the field of biomedicine, and discloses a spine implant design method and system using the self-sensing characteristic of a piezoelectric material, and the method comprises the steps: collecting spine three-dimensional image data and clinical diagnosis information, recognizing the spine lesion characteristic and the spine implantation part of a target patient, and determining the basic structure size of a spine implant; setting a perception sensitivity level of the spine implant in the body of the target patient to generate perception performance judgment conditions of the spine implant; analyzing the biocompatibility requirement of the spine implantation part, and identifying the biological adaptation mode of the piezoelectric material in the body of the target patient; and embedding a piezoelectric signal processing module in the spine implant, and executing parameter optimization processing of the spine implant in combination with the biological adaptation mode and the perception performance judgment condition to obtain a target spine implant. According to the invention, the working state of the postoperative implant and the rehabilitation progress of the spine can be accurately evaluated.

The present disclosure relates to delivery assemblies that include a measurement device for providing an indication, in real-time, of the position of a prosthetic valve relative to an anatomic structure at the site of implantation. In an example, the delivery assembly comprises a prosthetic valve and a delivery apparatus that includes a handle and a measurement device. The measurement device includes a sensor residing within the handle, a first motion transmitting member coupled to the sensor and extending distally from the handle to a free end thereof, and a second motion transmitting member coupled to the sensor and extending distally from the handle, such that its distal end is releasably coupled to the prosthetic valve. The sensor is configured to sense, in real time, axial movement of the second member's distal end relative to the first member's free end.

The application provides application of SEBS in implanting a biological electrode base. The biological electrode based on the SEBS base can be implanted in biological tissues, and is used for continuously or discontinuously analyzing physiological parameters of the biological body. Compared with other flexible bases, the SEBS base has the characteristics of being thinner and more flexible, can reduce the interference of body movement on the electrical signal, reduce the volume range of the implanted tissue and reduce the inflammatory reaction, thereby improving the measurement accuracy and long-term stability, is expected to meet more implantation site requirements when used for implanting a sensor, and has a good application prospect.

A system for delivering a collapsible and re-expandable prosthetic heart valve into a patient includes a valve support structure around which the valve is disposed in a collapsed condition. A sheath structure surrounds the collapsed valve, but can be moved relative to the valve to uncover it for expansion at the desired implant site in the patient. The sheath structure may be variously mounted and moved to deploy the valve in various ways. For example, the sheath structure may include multiple parts, each of which can be moved separately to separately deploy various parts of the valve. The apparatus may have other aspects, such as the ability to reverse deployment of the valve, the ability to pass other instrumentation through the valve delivery apparatus, the ability to be smoothly withdrawn from the patient after deployment of the valve, etc.

In some examples, a prosthetic heart valve for implantation within a native heart valve includes a radially expandable frame and a valvular structure. The frame includes an annular main body having an inflow end and an outflow end. The main body is radially expandable between a radially compressed state and a radially expanded state. The valvular structure includes a plurality of leaflets disposed within and coupled to the frame. The frame includes a plurality of frame anchors coupled to the main body. Each frame anchor is configured to be positioned on or around a pair of free edges of two of the native leaflets of the native heart valve. In some examples, a prosthetic heart valve delivery assembly includes a prosthetic heart valve and a delivery apparatus for delivering the prosthetic heart valve to an implantation site.

Provided herein are lead and stylet systems and methods of using the sty let to implant the lead into the brain. The leads may be used for deep brain stimulation (DBS) and may be connected to a cranially mounted implantable pulse generator (IPG) of a DBS sy stem. The lead may comprise a lumen configured to removably house the stylet to assist in implanting electrodes disposed on the lead in the brain. The lead and stylet systems described herein may allow for minimal excess lead length between the implantation site of the lead in the brain and the IPG (e.g., implanted in the skull).

The invention name of the present invention is a deployment system, tool and method for delivering an anchoring device for a prosthetic valve. In various embodiments, the delivery catheter is configured to deliver the anchoring device to the natural valve ring of the patient's heart, wherein the anchoring device can better fix the prosthesis at the natural valve ring. The delivery catheter may include a distal section, which includes one or more ridges or is laser cut to present a specific shape to better facilitate the delivery of the anchoring device at the implantation site, and may include a flexible tube, a first pull wire and a second pull wire. The flexible tube may include a hole extending between a first end and a second end, and the hole is sized to allow the anchoring device to pass therethrough. The distal portion may include a first flexure section and a second flexure section. Actuation of the first pull wire and the second pull wire can move the flexible tube from a first configuration to a second configuration.

Provided herein are devices and methods for improved oxygenation of biological cells transplanted into a biological subject. The devices and methods may be used to promote vascularization to a transplantation site of the biological subject, and / or may be used to improve survival and functionality of cells contained within an encapsulation device.

The invention discloses an orthodontic micro-implant nail implanting method, device and system and a storage medium. The method comprises the following steps: S1, acquiring CBCT three-dimensional data; and S2, analyzing CBCT three-dimensional data through AI artificial intelligence to calculate an optimal implantation site and an implantation direction path, and designing an implantation guide plate mounted on the surface of the dental crown. By the adoption of the technical scheme, the success rate of implanting the micro-implant nail is increased, relevant soft and hard tissue indexes in the CBCT three-dimensional image are integrated, and the burden and judgment errors of an orthodontic doctor in measurement and positioning are reduced.

The present disclosure relates to a magnetoelectric-based wireless bioimplant (MEWB) that can transmit biological activities sensed via a pair of electrodes to an external transceiver by leveraging magnetoelectric (ME) transducer that is coupled to the implant. The MEWB is also capable of wirelessly receiving power and data via the ME transducer from external transceiver when brought closer to the implanted site (e.g., at few centimeters), thus structuring a batteryless and a leadless bioimplant. MEWB may be implanted epidermally through a pair of electrodes on an organ to capture accurate biological activities. The external transceiver may include a transmitter coil for generating an alternating magnetic field and to transmit downlink data and a receiver coil to sense a backscattered field generated by MEWB and to demodulate uplink data. The overall structure of the disclosed implant is adopted enabling compactness, miniaturization (e.g., <3cm in length and <4mm in diameter) and endovascular delivery.

A method of treating a patient in need of an orthopedic implant is described. The method includes obtaining the T-score or bone density of the patient's native bone at a site of implantation, said T-score or bone density being determined by a DEXA scan or other means of determining a T-score or bone density. The method further includes selecting an orthopedic implant that has about the same density as the native bone at the site of implantation, and implanting the orthopedic implant at the site of implantation.

An occlusion device or plug having a proximal plug section and a distal plug section. The plug sections may each be shifted between an unexpanded configuration and an expanded configuration at the deployment site to occlude the deployment site. A tubular member such as a silicone tube may be used to form an occlusion device or plug shiftable or expandable into a desired configuration. An intermediate section between a proximal plug section and a distal plug section may be configured to be manipulated at least to shift at least one of the plug sections from an expanded configuration to an unexpanded configuration. A pair of stents may be coupled together via an intermediate section in such manner such that manipulation of the intermediate section causes at least one of the stents to shift from an expanded configuration to an unexpanded configuration.

In some embodiments, a bone implant for percutaneous use is provided. The bone implant comprises a head, a body adjacent to the head and a tip opposite the head. At least the head, body or tip is configured to contact bone. An expandable member contacts at least one of the head, tip or body and is movable from an unexpanded configuration to an expanded configuration when deployed at a bone implant site. In some embodiments, a system for percutaneous bone harvesting is provided.

A method of implanting a prosthetic heart valve can include advancing a delivery apparatus with a prosthetic heart valve mounted on a distal end portion of the delivery apparatus in a radially compressed configuration distally until the prosthetic heart valve is disposed at a selected implantation site. The method can further include radially expanding the prosthetic heart valve by applying a proximally directed force to at least one actuation member of the delivery apparatus that is coupled to the prosthetic heart valve. When the proximally directed force applied to the at least one actuation member exceeds a predetermined force during the radially expanding the prosthetic heart valve, the method can include arresting movement of the at least one actuation member and stopping radially expanding the prosthetic heart valve.

A bone foundation guide system has a bone foundation guide including a body that is contoured to reversibly affix to a bone segment of a dental implant surgical site, the body being further contoured accept and to guide the cutting of a portion of the bone segment from a dental implant surgical site and as well as to alternatively support a dental implant surgical guide; the dental implant surgical guide; and a bone foundation guide prosthesis as an alternative to the dental implant surgical guide. The bone foundation guide prosthesis combines with the body to accommodate the bone segment portion as placed through the body prior to the bone segment portion being removed from the dental implant site through the use of the body.

This invention discloses a composite material, its preparation method, and an implant, belonging to the field of medical materials technology. The composite material is obtained by combining a piezoelectric material and a metal ion-releasing material; the metal ion-releasing material is selected from one or more of magnesium-based biodegradable alloys, iron and iron-based biodegradable alloys, and zinc and zinc-based biodegradable alloys. The composite material can adaptively generate microcurrents of varying magnitudes at different stages of patient recovery through the piezoelectric response of the piezoelectric material. These microcurrents promote intelligent degradation of the metal ion-releasing material that matches the patient's own recovery process. The resulting metal ions and the microcurrents jointly promote healing at the implantation site, which is of great significance for the development and application of implant materials.

This document discusses, among other things, systems and methods for robotically assisted implantation of an implant in a patient. A system includes an implant-positioning unit configured to engage an elongate member of the implant, and a control console communicatively coupled to the external positioning unit. The control console can have a user interface that enables a user to input motion control instructions. The control console can generate a motion control signal, according to a specific motion control instruction, to control the external positioning unit to propel the implant into a target implant site. The system can be used to robotically control the delivery and positing of a cochlear implant during a hearing-preservation cochlear implant surgery.

An introductory lead system can include a first implantable lead having a first electrode and a second implantable lead having a second electrode guided to an implant site by the first implantable lead. The second electrode can be implanted in a patient's heart at the same implant site as the first electrode or at a second implant site. The introductory lead system can be delivered to one or more implant sites using various methods, including at the Koch triangle for ventricular free wall to atrium (VfA) therapy, at the right ventricular septal wall for dual bundle branch pacing, or in the coronary vasculature for left-sided sensing and pacing.