27 results about "Implantation Site" patented technology

This invention discloses a composite material, its preparation method, and an implant, belonging to the field of medical materials technology. The composite material is obtained by combining a piezoelectric material and a metal ion-releasing material; the metal ion-releasing material is selected from one or more of magnesium-based biodegradable alloys, iron and iron-based biodegradable alloys, and zinc and zinc-based biodegradable alloys. The composite material can adaptively generate microcurrents of varying magnitudes at different stages of patient recovery through the piezoelectric response of the piezoelectric material. These microcurrents promote intelligent degradation of the metal ion-releasing material that matches the patient's own recovery process. The resulting metal ions and the microcurrents jointly promote healing at the implantation site, which is of great significance for the development and application of implant materials.

A holder for an annuloplasty ring that detaches with one cut. The annuloplasty ring mounts around a periphery of the holder without the use of connecting sutures. The holder has a proximal plate defining a lip on one side of the ring, and a distal retainer that defines a second lip on the other side, the two lips retaining the ring around the holder periphery. The distal retainer is formed by two hinged wings. A truss suture maintains the holder in a trussed configuration while the annuloplasty ring is delivered and secured to the implantation site. Once the ring is secured at the annulus, the truss suture is severed with one cut, enabling the hinged wings to pivot and the holder to be pulled free of the ring.

A stent graft for treating an arterial aneurysm includes loops fixed to struts of stents, wherein the struts define distal and proximal apices. The ends of a ligature can be linked by a wire in a stent graft delivery system that threads anchor loops longitudinally spanning ends of the ligature to maintain the stent in a radially constricted position during delivery to the aneurysm. A delivery system and method for implanting a stent graft prosthesis includes and employs a torque component at a distal end of the stent graft prosthesis, whereby following advancement of the stent graft to a surgical site in a constrained or partially constrained configuration, torque is applied to the torque component to rotationally align the stent graft about a longitudinal axis of the stent graft, followed by deployment of the stent graft in correct rotational alignment. A delivery system and method of its use includes an apex capture assembly, a leg clasp, and a leg stop for capturing a stent graft during orientation and stabilization at an implantation site of a surgical site.

This invention discloses a method for preparing a strontium titanate modified layer on the surface of zirconia based on an impregnation-heat treatment method, comprising: (1) mixing titanium sulfate, urea and water to obtain a precursor liquid A, placing zirconia ceramic in the precursor liquid A, heating to boiling and maintaining for a period of time, then removing the zirconia ceramic, and after heat treatment A, preparing a titanium dioxide film on the surface of zirconia; (2) mixing H2O2 aqueous solution, ammonia and deionized water, adding metatitanic acid and stirring to dissolve, obtaining a precursor liquid B, placing the zirconia with the titanium dioxide film in the precursor liquid B, and allowing it to stand and react for a period of time at room temperature, depositing zirconia modified with a titanium dioxide precursor layer; (3) dissolving strontium acetate, or a mixed salt composed of calcium acetate and / or magnesium acetate and strontium acetate in deionized water to obtain an impregnation treatment solution, placing the zirconia modified with the titanium dioxide precursor layer in the impregnation treatment solution, allowing it to stand and react for a period of time, and then removing it, and after heat treatment B, preparing a strontium titanate modified layer on the surface of zirconia. The strontium titanate layer prepared on the surface of zirconia ceramic in this invention is tightly attached to the zirconia substrate and has high hydrophilicity, which is conducive to the adhesion of proteins and cells in the human body. At the same time, it can release active factors such as strontium ions for a long time to promote bone formation and bone regeneration at the implantation site, ultimately enhancing the osseointegration capacity of the zirconia implant.

This invention relates to the field of teaching model equipment, specifically a support device for rhinoplasty surgery. It includes a fixed frame with arc-shaped sides and a straight middle section. An adjustment strap is connected to the rear of the fixed frame. An installation groove is formed on the upper front side of the fixed frame, inside which a control sleeve is placed. The support body is housed within the control sleeve. The support body is cylindrical, and a push rod is installed inside. The outer side of the push rod fits against the inner side of the support body, with one end extending out of the support body. When the fixed frame is installed on the patient's face, the prosthesis can be inserted into the opening of the support body. The support body then slides within the control sleeve. A ball joint rotates within a ball joint groove, controlling the up, down, left, and right swing angles of the support body to achieve precise alignment with the opening. Finally, pushing the push rod allows the prosthesis to be precisely inserted into the desired implantation site.

The utility model provides a stomach pacemaker electrode, namely a stomach pacemaker, and relates to the technical field of gastrointestinal pacing equipment, the stomach pacemaker electrode comprises an electrode main body; the electrode main body is provided with an implanting part, a suturing part and a wiring part; the implantation part is located at one end of the electrode main body and can penetrate into the outer wall of the stomach to fix the electrode main body; the suturing part is arranged on one side of the implanting part, and the suturing part is used for being matched with a suturing line so that the suturing line can tightly press the electrode body on the surface of the outer wall of the stomach; the wiring part is located at the other end of the electrode body and used for being connected with a wire. The wiring part is used for welding a wire to be connected with the chip, the implanting part penetrates into the outer wall of the stomach, the other end of the electrode main body is fixedly bound on the outer wall of the stomach through a suture line, the suture line is used for tightly pressing the suture line on the outer wall of the stomach, the two ends of the electrode main body are fixed to ensure that the electrode main body can be attached to the tissue of the stomach, and the fixing effect is excellent; the electrode main body is firmly attached to stomach tissue, and electric signal conduction is stable.

An implantable sensor system using one or more sensor implants comprised of micro-electrical mechanical system (MEMS) sensors for the accurate and continuous measurement of physiological hemodynamic signals such as diastolic and systolic blood pressure. Sensor implants are configured to be subcutaneously injected to a placement site adjacent a blood vessel. In some embodiments, sensors comprise micromachined ultrasonic transducers.

This application provides a method and system for recommending gold marker implantation sites, relating to the field of image-guided radiotherapy technology. The method includes acquiring a patient's CT image data; determining several gold marker implantation points based on the CT image data; combining the gold marker implantation points according to preset aggregation rules to construct several gold marker point sets; evaluating the three-dimensional geometric stability index and the two-dimensional observable stability index of each gold marker point set; combining the preset evaluation rules and the geometric stability index and observable stability index corresponding to each gold marker point set to select the optimal gold marker point set from all gold marker point sets; using the gold marker implantation points in the optimal gold marker point set as recommended gold marker implantation sites; and proactively recommending the optimal implantation point by quantitatively evaluating the geometric stability and observable stability of the gold marker based on CT images before implantation, thereby preventing distribution degradation problems, avoiding rework after implantation, and ensuring tracking accuracy and treatment efficiency from the source.

The present disclosure relates to valve replacement devices that are foldable for catheter-based deployment to the site of implantation, as well as systems for the delivery of valve prostheses, including prostheses having the special characteristics of the disclosed valve replacement devices. The devices include highly effective adhering mechanisms for secure and enduring precision implantation. The adhering mechanisms may employ a unique sealing mechanism that includes a cuff that expands slowly whereby the device is not secured in place until the completion of the implantation procedure. The implanted device, optionally together with the cuff, prevents perivalvular leaks and incorporate an appropriate leaflet system for reliable functioning in situ.

In some embodiments, a bone implant for percutaneous use is provided. The bone implant comprises a head, a body adjacent to the head and a tip opposite the head. At least the head, body or tip is configured to contact bone. An expandable member contacts at least one of the head, tip or body and is movable from an unexpanded configuration to an expanded configuration when deployed at a bone implant site. In some embodiments, a system for percutaneous bone harvesting is provided.

An apparatus configured to facilitate delivery of an embryo to an implantation site on an endometrium of a patient is provided. The apparatus comprises one or more walls defining a cavity, the walls comprising a rim configured for adhering to the endometrium and defining an opening to the cavity. The walls comprise one or more throughgoing apertures, each sized to allow passage therethrough of intrauterine environmental molecules, and to prevent passage therethrough of a blastocyst. The material of the walls is configured to degrade in the intrauterine environment within a predetermined range of time.

The invention relates to a device comprising an implant, in particular in the form of a stent, which can be expanded into an implanted state, wherein the device also has an active-substance-releasing system, which is or can be connected at least partially or in regions to the implant and can be introduced into the body of the patient separately or together with the implant in a compressed insertion state, in particular minimally invasively, and can be expanded at the implantation site into an implanted state. According to the invention, it is provided in particular that the active-substance-releasing system is designed in such a way that it is not subjected to any or at least substantially not to any non-linear elastic and / or plastic deformation during the expansion of the implant at the implantation site and / or during the expansion of the active-substance-releasing system at the implantation site and during the associated change in shape of the implant and / or of the active-substance-releasing system.

An implantable medical device that is adapted to be implanted at an implantation site includes an expandable frame that is adapted to expand from a collapsed configuration to an expanded configuration. The expandable frame includes an upper crown portion, a lower crown portion, commissural posts that extend proximally from the upper crown portion, and stabilization arches that extend proximally from the commissural posts. One or more valve cusps are secured relative to the expandable frame. An inner skirt is disposed along an inner portion of the lower crown portion and an outer skirt is disposed along an outer portion of the lower crown portion of the expandable frame. An expandable member is secured to the outer skirt.

A medical device system is provided for guiding implantation of a medical electrical lead. The system includes processing circuitry configured to receive first patient body image data and second patient body image data and register the first patient body image data and the second patient body image data. The processing circuitry may be further configured to receive a signal from at least one location sensor disposed at a known distance from a feature of a removable outer sheath of a delivery tool configured to deliver an extravascular lead to an implant site of a patient via a non-transvenous pathway. The processing circuitry may determine from the location sensor signal a location of a feature of the removable outer sheath in a coordinate system space corresponding to the second patient body image data.

The application discloses a preparation method and application of a metal organic framework composite coating of active molecules loaded on a zinc alloy surface, and belongs to the technical field of biomedically degradable metal materials. The preparation method of the organic metal framework composite coating comprises the following steps: S1, preparing a ZnO nanostructure transition layer; S2, in-situ generating a metal organic framework coating induced by 2,5-dihydroxyterephthalic acid; and S3, preparing a metal organic framework composite coating loaded with deferoxamine. The application can effectively slow down the degradation rate of a zinc alloy substrate containing Mg, Ca and Sr, and makes the zinc alloy substrate containing Mg, Ca and Sr free of local corrosion, so that no toxicity is caused to cells and tissues around an implantation site. Slow release of the loaded deferoxamine can significantly accelerate blood supply reconstruction at a fracture / bone defect site, and can balance osteogenesis and osteoclastogenesis. The application solves the problems of uncontrollable degradation and lack of regulation on local immune inflammation and osteogenesis-osteoclastogenesis balance.

The invention relates to a medical device for treating a heart valve affected by inflammation and / or infection or for treating a heart valve defect, in particular heart valve insufficiency or heart valve stenosis, wherein the medical device comprises a stent, in particular a self-expanding stent, which can be introduced into the body of a patient in a radially compressed form in a minimally invasive manner using an introduction catheter system via the femoral route and can be converted into an expanded form at the implantation site at the heart valve to be treated.According to the invention, it is particularly provided that the stent has a base body with a proximal end region and a distal end region and at least two functional arms which are connected to the base body of the stent, wherein the at least two functional arms are oriented cranially towards the distal end region of the base body in the radially compressed form of the stent and caudally towards the proximal end region of the base body in the expanded form of the stent.

The invention relates to a device, in particular for treating a heart valve of a patient that is diseased with inflammation and / or infection, wherein the device has an implant which, in a compressed state, can be inserted into the patient's body, in particular in a minimally invasive manner, and which is expandable at the implantation site, preferably at a heart valve to be treated, and wherein the device further has a drug-releasing system which is at least partially or partially connected or connectable to the implant and can be inserted into the patient's body separately or together with the implant, in particular in a minimally invasive manner, and which is expandable at the implantation site.According to the invention, it is particularly provided that the drug-releasing system is designed in such a way that, during the expansion of the implant at the implantation site and / or during the expansion of the drug-releasing system at the implantation site and during the associated change in shape of the implant and / or the drug-releasing system, it is not subjected to any or at least substantially no non-linear elastic and / or plastic deformation.

Methods and devices for delivering bone material are disclosed. The bone delivery device may include a cannula and a cartridge in fluid communication with the cannula, wherein the cartridge comprises a base containing one or more delivery channels configured to receive bone material. The bone material within the delivery channel(s) is compacted to a second diameter smaller than the first diameter. The method includes actuating the compacted bone material from the cartridge through the cannula to deliver the bone material to an implantation site.

A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.

Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

The invention relates to a delivery catheter system for introducing and positioning a heart valve stent into a patient's body, wherein the stent comprises a base body with a proximal end region and an opposing distal end region, and at least two attachment / anchoring / positioning arcs affixed to the base body. These arcs are oriented cranially towards the distal end region of the base body in the compressed form of the stent and caudally towards the proximal end region of the base body in the expanded form of the stent. The delivery catheter system includes a catheter system through which the stent, in its compressed form, can be introduced into the patient's body, a catheter tip provided at the proximal end of the catheter system in which the stent, in its compressed form, can be received, and a handle provided at the distal end of the catheter system with which the catheter tip can be manipulated.According to the invention, it is particularly provided that the handle has actuating means which interact with the catheter tip in such a way that, when the actuating means are actuated, the at least two fastening / anchoring / positioning arcs of the stent can be successively released step by step from the catheter tip according to a predetermined or definable sequence of events.

The present application relates to a kind of delivery device for delivering artificial valve, the delivery device includes: covering body, is tubular and is used to cover artificial valve, the covering body is equipped with the flow-through hole being communicated with its inner cavity and the outside world;Inner sheath, can slide relative to the covering body;And sheath core mechanism, slidingly arranged in the inner sheath and connected with the covering body, the sheath core mechanism is used for with artificial valve detachably connected.In the release process of artificial valve, blood can flow out from the covering body through the flow-through hole.By artificial valve is housed in covering body, when input to implantation site, there is a certain gap between covering body and annulus, on the one hand, blood can flow through the gap between covering body and annulus, on the other hand, blood enters artificial valve and flows out from the flow-through hole on covering body.Avoid the displacement of covering body and artificial valve under the action of larger blood pressure, improve the position accuracy after artificial valve implantation.

This application relates to the field of medical device technology, and discloses a clutch assembly, a delivery system, and an interventional treatment system. The clutch assembly is disposed at the distal end of a catheter and includes at least two engaging members. In their natural state, the at least two engaging members are open relative to the central axis of the clutch assembly. A connecting portion is provided at the distal end of each engaging member. Under external force, the at least two engaging members close together, allowing the connecting portion to engage with a connector on the implant. The proximal and / or distal ends of the connecting portion have contact structures that abut against the connector, creating a contact position between the connecting portion and the connector. By providing these contact structures, this application facilitates the separation of the connecting portion and the connector while simultaneously limiting minute relative displacement between them. This ensures the implant remains stable during implantation, preventing deviation from its relative position to the implantation site and avoiding unintended movement, thus promoting a smooth surgical procedure.

This invention discloses a method comprising locating a Koch triangle region in the right atrium of a patient's heart; securing at least one electrode of an implantable lead or device from the Koch triangle region to cardiac tissue for delivery of atrium-to-ventricle (VfA) cardiac therapy; and testing the position or depth of the at least one electrode to configure the VfA cardiac therapy. Locating the target implantation area in the Koch triangle region may include detecting atrial slow path potentials (ASP) or atrial pacing outputs.

The utility model relates to technical fields, concretely is free end molar implantation positioner, including clamping part and the adjusting part of fixed above clamping part, the clamping part includes the main chuck and the auxiliary chuck of opposite setting, the limiting arm of fixed above auxiliary chuck and the locating arm of fixed in auxiliary chuck side, the limiting arm is L type, one end of limiting arm is above the space between main chuck and auxiliary chuck, be equipped with the locating hole on the locating arm, and the adjusting part is used for controlling the distance between main chuck and auxiliary chuck. This kind of implantation positioner is embraced with adjacent tooth with main auxiliary chuck, cooperates adjusting part and limiting arm, breaks through the limitation of traditional dependence on former implantation, accurately determines the implantation site, reduces the operation risk, promotes the repair efficiency, and simultaneously, its flexible adjustable, quick dismounting characteristics, adapt to different adjacent tooth size, greatly shorten the operation time, significantly enhance clinical operation convenience, also help to reduce the operation risk, bring more safe, more comfortable treatment experience for the patient.

Apparatuses, systems, and methods for prosthetic valves. Embodiments of prosthetic valves may be directed to improvements in anchoring to an implantation site and / or sealing flow at an implantation site, which may comprise a native valve. Embodiments may be configured to conform to a shape of a native valve, which may be a non-circular shape. Such native valves may include native valve annuli having oval shapes and / or shapes that include one or more recesses. Improvements in anchoring to implantation sites are disclosed as well.

A guided implant planning system and an instrument adapter, comprising: a planning module comprising at least one processor and one memory, wherein the memory stores instructions executable by the processor to: Receipt of patient-specific anatomical data corresponding to a target implantation site; to process the anatomical data in order to generate a three-dimensional representation of the target implantation site; and Determination of a virtual implant placement plan that includes at least one position, one angular orientation, and one depth of an implant relative to the anatomical structures; and an instrument adapter configured to be functionally coupled to one or more surgical instruments, wherein the instrument adapter includes at least one guide interface designed to: Alignment of one or more surgical instruments onto a predefined implant path that corresponds to the virtual implant placement plan; and to restrict the movement of one or more surgical instruments so that they essentially follow the predefined implant path during a surgical procedure, the system is configured to translate the virtual implant placement plan into a guided intraoperative execution to facilitate accurate implant placement.